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Stephen J. Meltzer - Publications

Affiliations: 
University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular Biology, Medicine and Surgery, Genetics
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Year Citation  Score
2021 Kandimalla R, Xu J, Link A, Matsuyama T, Yamamura K, Parker MI, Uetake H, Balaguer F, Borazanci E, Tsai S, Evans D, Meltzer SJ, Baba H, Brand R, Von Hoff D, et al. EpiPanGI Dx: A cell-free DNA methylation fingerprint for the early detection of gastrointestinal cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34465601 DOI: 10.1158/1078-0432.CCR-21-1982  0.304
2020 Kandimalla R, Xu J, Link A, Matsuyama T, Yamamura K, Parker I, Uetake H, Hernandez-Illan E, Lozano J, Borazanci E, Tsai S, Evans D, Meltzer SJ, Baba H, Brand R, et al. Abstract 1084: EpiPanGI-Dx: A cell-free DNA methylation fingerprint for the early detection of gastrointestinal cancers Cancer Research. 80: 1084-1084. DOI: 10.1158/1538-7445.Am2020-1084  0.405
2019 Chen L, Huang M, Plummer J, Pan J, Jiang YY, Yang Q, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan N, ... ... Meltzer SJ, et al. Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma. Gut. PMID 31409603 DOI: 10.1136/Gutjnl-2019-318325  0.365
2019 Ng CK, Ma K, Cheng Y, Miyashita T, Harmon JW, Meltzer SJ. Krüppel-like Factor 5 Promotes Sonic Hedgehog Signaling and Neoplasia in Barrett's Esophagus and Esophageal Adenocarcinoma. Translational Oncology. 12: 1432-1441. PMID 31401336 DOI: 10.1016/J.Tranon.2019.07.006  0.353
2019 Lin Y, Dong H, Deng W, Lin W, Li K, Xiong X, Guo Y, Zhou F, Ma C, Chen Y, Ren H, Yang H, Dai N, Ma L, Meltzer SJ, et al. Evaluation of salivary exosomal chimeric RNA as a potential biomarker in esophageal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30745298 DOI: 10.1158/1078-0432.Ccr-18-3169  0.312
2019 Wang Z, Ma K, Cheng Y, Meltzer SJ. Tu2030 – Novel Circular Rna Nf1 Acts As a Sponge, Promoting Gastric Cancer by Absorbing Mir-16 Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39908-1  0.332
2018 Wang Z, Ma K, Pitts S, Cheng Y, Liu X, Ke X, Kovaka S, Ashktorab H, Smoot DT, Schatz M, Wang Z, Meltzer S. Novel circular RNA NF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16. Endocrine-Related Cancer. PMID 30576282 DOI: 10.1530/Erc-18-0478  0.358
2018 Peng Y, Zhang X, Lin H, Deng S, Huang Y, Qin Y, Feng X, Yan R, Zhao Y, Cheng Y, Wei Y, Wang J, Chen W, Fan X, Ashktorab H, ... ... Meltzer SJ, et al. Inhibition of miR‑194 suppresses the Wnt/β‑catenin signalling pathway in gastric cancer. Oncology Reports. PMID 30542715 DOI: 10.3892/Or.2018.6773  0.366
2018 Xiong JX, Wang YS, Sheng J, Xiang D, Huang TX, Tan BB, Zeng CM, Li HH, Yang J, Meltzer SJ, Mori Y, Qin YR, Guan XY, Fu L. Epigenetic alterations of a novel antioxidant gene predispose susceptible individuals to increased risk of esophageal cancer. International Journal of Biological Sciences. 14: 1658-1668. PMID 30416380 DOI: 10.7150/Ijbs.28482  0.409
2018 Liu X, Abraham JM, Cheng Y, Wang Z, Wang Z, Zhang G, Ashktorab H, Smoot DT, Cole RN, Boronina TN, DeVine LR, Talbot CC, Liu Z, Meltzer SJ. Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation. Molecular Therapy. Nucleic Acids. 13: 312-321. PMID 30326427 DOI: 10.1016/J.Omtn.2018.09.010  0.303
2018 Liu X, Cheng Y, Abraham JM, Wang Z, Wang Z, Ke X, Yan R, Shin EJ, Ngamruengphong S, Khashab M, Zhang G, McNamara G, Ewald AJ, Lin D, Liu Z, ... Meltzer SJ, et al. Modeling Wnt signaling by CRISPR-Cas9 genome editing facilitates neoplasia in human Barrett epithelial organoids. Cancer Letters. PMID 30144514 DOI: 10.1016/J.Canlet.2018.08.017  0.32
2018 Zhang X, Peng Y, Huang Y, Deng S, Feng X, Hou G, Lin H, Wang J, Yan R, Zhao Y, Fan X, Meltzer SJ, Li S, Jin Z. Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression. Cell Death & Disease. 9: 778. PMID 30006518 DOI: 10.1038/S41419-018-0785-5  0.34
2018 Xie JJ, Jiang YY, Jiang Y, Li CQ, Chee LM, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, ... ... Meltzer SJ, et al. Increased Expression of the Long Non-coding RNA LINC01503, Regulated by TP63, in Squamous Cell Carcinoma and Effects on Oncogenic Activities of Cancer Cell Lines. Gastroenterology. PMID 29454790 DOI: 10.1053/J.Gastro.2018.02.018  0.37
2018 Ng CK, Cheng Y, Abraham JM, Meltzer SJ. Abstract 3077: Krüppel-like factor 5 and its connection to Sonic Hedgehog signaling in Barrett's esophagus and esophageal adenocarcinoma Cancer Research. 78: 3077-3077. DOI: 10.1158/1538-7445.Am2018-3077  0.4
2017 Wang Z, Cheng Y, Abraham JM, Yan R, Liu X, Chen W, Ibrahim S, Schroth GP, Ke X, He Y, Meltzer SJ. RNA sequencing of esophageal adenocarcinomas identifies novel fusion transcripts, including NPC1-MELK, arising from a complex chromosomal rearrangement. Cancer. PMID 28640357 DOI: 10.1002/Cncr.30837  0.322
2017 Abraham JM, Meltzer SJ. Long Noncoding RNAs in the Pathogenesis of Barrett's Esophagus and Esophageal Carcinoma. Gastroenterology. PMID 28528706 DOI: 10.1053/J.Gastro.2017.04.046  0.311
2017 Liu X, Meltzer SJ. Gastric Cancer in the Era of Precision Medicine. Cellular and Molecular Gastroenterology and Hepatology. 3: 348-358. PMID 28462377 DOI: 10.1016/J.Jcmgh.2017.02.003  0.37
2017 Sun Z, Ke X, Salzberg SL, Kim D, Antonescu V, Cheng Y, Huang B, Song JH, Abraham JM, Ibrahim S, Tian H, Meltzer SJ. The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus. Cancer. PMID 28081303 DOI: 10.1002/Cncr.30510  0.351
2016 Li L, Piontek K, Ishida M, Fausther M, Dranoff JA, Fu R, Mezey E, Gould SJ, Fordjour FK, Meltzer SJ, Sirica AE, Selaru FM. Extracellular vesicles carry miR-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. Hepatology (Baltimore, Md.). PMID 27474881 DOI: 10.1002/Hep.28735  0.312
2016 Yan R, Zhu K, Dang C, Lan K, Wang H, Yuan D, Chen W, Meltzer SJ, Li K. Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response. Oncotarget. PMID 27246972 DOI: 10.18632/Oncotarget.9606  0.371
2016 Sun Z, Liu X, Song JH, Cheng Y, Liu Y, Jia Y, Meltzer SJ, Wang Z. TNFAIP8 overexpression: a potential predictor of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma after Ivor Lewis esophagectomy. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26886285 DOI: 10.1007/S13277-016-4978-1  0.382
2016 Huang B, Song JH, Cheng Y, Abraham JM, Ibrahim S, Sun Z, Ke X, Meltzer SJ. Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression. Oncogene. PMID 26876208 DOI: 10.1038/Onc.2016.25  0.391
2016 Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, et al. Whole-exome Sequencing analyses of Inflammatory Bowel Disease-associated Colorectal Cancers. Gastroenterology. PMID 26764183 DOI: 10.1053/J.Gastro.2015.12.036  0.396
2016 Kambhampati S, Xu Y, Meltzer S. Risk Factors for Progression of Barrettʼs Esophagus to High-Grade Dysplasia and Esophageal Carcinoma: 456 The American Journal of Gastroenterology. 111. DOI: 10.14309/00000434-201610001-00456  0.321
2016 Robles AI, Traverso G, Zhang M, Roberts N, Khan MA, Joseph C, Lauwers G, Selaru F, Popoli M, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, et al. Abstract 127: The genomic landscapes of inflammatory bowel disease-associated colorectal cancers Cancer Research. 76: 127-127. DOI: 10.1158/1538-7445.Am2016-127  0.439
2015 Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S. TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling. Oncotarget. PMID 26416455 DOI: 10.18632/Oncotarget.5362  0.355
2015 Doucet-O'Hare TT, Rodić N, Sharma R, Darbari I, Abril G, Choi JA, Young Ahn J, Cheng Y, Anders RA, Burns KH, Meltzer SJ, Kazazian HH. LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 112: E4894-900. PMID 26283398 DOI: 10.1073/Pnas.1502474112  0.367
2015 Tang X, Wang Y, Fan Z, Ji G, Wang M, Lin J, Huang S, Meltzer SJ. Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26237271 DOI: 10.1038/Labinvest.2015.86  0.344
2015 Cheng Y, Kiess AP, Herman JM, Pomper MG, Meltzer SJ, Abraham JM. Phosphorus-32, a clinically available drug, inhibits cancer growth by inducing DNA double-strand breakage. Plos One. 10: e0128152. PMID 26030880 DOI: 10.1371/Journal.Pone.0128152  0.332
2014 Ning Z, Zhu H, Li F, Liu Q, Liu G, Tan T, Zhang B, Chen S, Li G, Huang D, Meltzer SJ, Zhang H. Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent. Genes & Cancer. 5: 436-44. PMID 25568668 DOI: 10.18632/Genesandcancer.38  0.309
2014 Jain S, Xie L, Boldbaatar B, Lin SY, Hamilton JP, Meltzer SJ, Chen SH, Hu CT, Block TM, Song W, Su YH. Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis. Hepatology Research : the Official Journal of the Japan Society of Hepatology. PMID 25382672 DOI: 10.1111/Hepr.12449  0.363
2014 Jin Z, Wang L, Cao Z, Cheng Y, Gao Y, Feng X, Chen S, Yu H, Wu W, Zhao Z, Dong M, Zhang X, Liu J, Fan X, Mori Y, ... Meltzer SJ, et al. Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis. Bmc Cancer. 14: 345. PMID 24885118 DOI: 10.1186/1471-2407-14-345  0.418
2014 Michailidi C, Soudry E, Brait M, Maldonado L, Jaffe A, Ili-Gangas C, Brebi-Mieville P, Perez J, Kim MS, Zhong X, Yang Q, Valle B, Meltzer SJ, Torbenson M, Esteller M, et al. Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials. Gastroenterology Research and Practice. 2014: 597164. PMID 24829571 DOI: 10.1155/2014/597164  0.334
2014 Hamilton JP, Potter JJ, Koganti L, Meltzer SJ, Mezey E. Effects of vitamin D3 stimulation of thioredoxin-interacting protein in hepatocellular carcinoma. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 44: 1357-66. PMID 24451003 DOI: 10.1111/Hepr.12302  0.313
2014 Yang X, Song JH, Cheng Y, Wu W, Bhagat T, Yu Y, Abraham JM, Ibrahim S, Ravich W, Roland BC, Khashab M, Singh VK, Shin EJ, Yang X, Verma AK, ... Meltzer SJ, et al. Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells. Gut. 63: 881-90. PMID 24000294 DOI: 10.1136/Gutjnl-2013-305266  0.374
2014 Tang X, Meltzer SJ, Zhi-ning F, Huang S. Su1964 Klotho Expression in Esophageal Squamous Cell Carcinoma and Its Association With β-Catenin and Disease Progression Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61844-8  0.331
2013 Jin Z, Wang L, Zhang Y, Cheng Y, Gao Y, Feng X, Dong M, Cao Z, Chen S, Yu H, Zhao Z, Zhang X, Liu J, Mori Y, Fan X, ... Meltzer SJ, et al. MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma. Scientific Reports. 3: 2838. PMID 24088706 DOI: 10.1038/Srep02838  0.37
2013 Jin Z, Zhao Z, Cheng Y, Dong M, Zhang X, Wang L, Fan X, Feng X, Mori Y, Meltzer SJ. Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer. Cancer. 119: 3604-9. PMID 23893879 DOI: 10.1002/Cncr.28276  0.403
2013 Merchant NB, Dutta SK, Girotra M, Arora M, Meltzer SJ. Evidence for enhanced telomerase activity in Barrett's esophagus with dysplasia and adenocarcinoma. Asian Pacific Journal of Cancer Prevention : Apjcp. 14: 679-83. PMID 23621218 DOI: 10.7314/Apjcp.2013.14.2.679  0.307
2013 Wang LD, Bi X, Song X, Pohl NM, Cheng Y, Zhou Y, Shears S, Ansong E, Xing M, Wang S, Xu XC, Huang P, Xu L, Wang L, Fan Z, ... ... Meltzer SJ, et al. A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis. Molecular Carcinogenesis. 52: E80-6. PMID 23390063 DOI: 10.1002/Mc.22016  0.405
2013 Wu W, Bhagat TD, Yang X, Song JH, Cheng Y, Agarwal R, Abraham JM, Ibrahim S, Bartenstein M, Hussain Z, Suzuki M, Yu Y, Chen W, Eng C, Greally J, ... ... Meltzer SJ, et al. Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology. 144: 956-966.e4. PMID 23333711 DOI: 10.1053/J.Gastro.2013.01.019  0.354
2013 Takahashi T, Shigematsu H, Shivapurkar N, Reddy J, Zheng Y, Feng Z, Suzuki M, Nomura M, Augustus M, Yin J, Meltzer SJ, Gazdar AF. Erratum: Aberrant promoter methylation of multiple genes during multistep pathogenesis of colorectal cancers(International Journal of Cancer (2012) 132 (499)) International Journal of Cancer. 132. PMID 23169200 DOI: 10.1002/Ijc.27883  0.401
2013 Takahashi T, Suzuki M, Shigematsu H, Shivapurkar N, Echebiri C, Nomura M, Stastny V, Augustus M, Wu CW, Wistuba II, Meltzer SJ, Gazdar AF. Erratum: Aberrant methylation of reprimo in human malignancies(International Journal of Cancer (2013) 132 (498)) International Journal of Cancer. 132. PMID 23169199 DOI: 10.1002/Ijc.27882  0.365
2013 Marimuthu A, Subbannayya Y, Sahasrabuddhe NA, Balakrishnan L, Syed N, Sekhar NR, Katte TV, Pinto SM, Srikanth SM, Kumar P, Pawar H, Kashyap MK, Maharudraiah J, Ashktorab H, Smoot DT, ... ... Meltzer SJ, et al. SILAC-based quantitative proteomic analysis of gastric cancer secretome. Proteomics. Clinical Applications. 7: 355-66. PMID 23161554 DOI: 10.1002/Prca.201200069  0.402
2013 Song JH, Meltzer SJ. Abstract 1839: Long non-coding RNA SS-001 regulates proliferation, cell cycle, and migration in esophageal adenocarcinoma cells. Cancer Research. 73: 1839-1839. DOI: 10.1158/1538-7445.Am2013-1839  0.388
2012 Agrawal N, Jiao Y, Bettegowda C, Hutfless SM, Wang Y, David S, Cheng Y, Twaddell WS, Latt NL, Shin EJ, Wang LD, Wang L, Yang W, Velculescu VE, Vogelstein B, ... ... Meltzer SJ, et al. Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer Discovery. 2: 899-905. PMID 22877736 DOI: 10.1158/2159-8290.Cd-12-0189  0.414
2012 Kathiria AS, Neumann WL, Rhees J, Hotchkiss E, Cheng Y, Genta RM, Meltzer SJ, Souza RF, Theiss AL. Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses. Cancer Research. 72: 5778-89. PMID 22869582 DOI: 10.1158/0008-5472.Can-12-0603  0.357
2012 Song JH, Meltzer SJ. MicroRNAs in pathogenesis, diagnosis, and treatment of gastroesophageal cancers. Gastroenterology. 143: 35-47.e2. PMID 22580099 DOI: 10.1053/J.Gastro.2012.05.003  0.351
2012 Cheng Y, Senthamizhchelvan S, Agarwal R, Green GM, Mease RC, Sgouros G, Huso DL, Pomper MG, Meltzer SJ, Abraham JM. [32P]ATP inhibits the growth of xenografted tumors in nude mice. Cell Cycle (Georgetown, Tex.). 11: 1878-82. PMID 22544324 DOI: 10.4161/Cc.19955  0.307
2012 Jain S, Chen S, Chang KC, Lin YJ, Hu CT, Boldbaatar B, Hamilton JP, Lin SY, Chang TT, Chen SH, Song W, Meltzer SJ, Block TM, Su YH. Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma. Plos One. 7: e35789. PMID 22536438 DOI: 10.1371/Journal.Pone.0035789  0.334
2012 Cheng Y, Jin Z, Agarwal R, Ma K, Yang J, Ibrahim S, Olaru AV, David S, Ashktorab H, Smoot DT, Duncan MD, Hutcheon DF, Abraham JM, Meltzer SJ, Mori Y. LARP7 is a potential tumor suppressor gene in gastric cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 1013-9. PMID 22488152 DOI: 10.1038/Labinvest.2012.59  0.411
2012 Yamanaka S, Olaru AV, An F, Luvsanjav D, Jin Z, Agarwal R, Tomuleasa C, Popescu I, Alexandrescu S, Dima S, Chivu-Economescu M, Montgomery EA, Torbenson M, Meltzer SJ, Selaru FM. MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 44: 589-96. PMID 22464652 DOI: 10.1016/J.Dld.2012.02.016  0.35
2012 You YJ, Chen YP, Zheng XX, Meltzer SJ, Zhang H. Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients. Cancer Letters. 315: 138-44. PMID 22099875 DOI: 10.1016/J.Canlet.2011.08.032  0.387
2012 Vega KJ, May R, Sureban SM, Lightfoot SA, Qu D, Reed A, Weygant N, Ramanujam R, Souza R, Madhoun M, Whorton J, Anant S, Meltzer SJ, Houchen CW. Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma. Journal of Gastroenterology and Hepatology. 27: 773-80. PMID 21916995 DOI: 10.1111/J.1440-1746.2011.06928.X  0.317
2012 Olaru AV, Cheng Y, Agarwal R, Yang J, David S, Abraham JM, Yu W, Kwon JH, Lazarev M, Brant SR, Marohn MR, Hutcheon DF, Harpaz N, Meltzer SJ, Mori Y. Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers. Inflammatory Bowel Diseases. 18: 641-8. PMID 21830278 DOI: 10.1002/Ibd.21826  0.366
2012 Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I, Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, ... ... Meltzer SJ, et al. A DNA methylation fingerprint of 1628 human samples. Genome Research. 22: 407-19. PMID 21613409 DOI: 10.1101/Gr.119867.110  0.328
2012 Li L, Cheng Y, Ibrahim S, Meltzer S, Mori Y. Abstract A30: DNA methylation field defects in colorectal cancer patients. Cancer Prevention Research. 5. DOI: 10.1158/1940-6207.Prev-12-A30  0.352
2012 Agarwal R, Mori Y, Cheng Y, Abraham JM, Montgomery E, Meltzer SJ. Abstract LB-384: BARX1, CYGB, and other epigenetic targets of gastric cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-384  0.453
2012 Wu W, Song JH, Cheng Y, Meltzer SJ. Abstract 5042:A-AS1, a long non-protein coding RNA overexpressed in esophageal adenocarcinoma, influences cancer cell proliferation and apoptosis Cancer Research. 72: 5042-5042. DOI: 10.1158/1538-7445.Am2012-5042  0.321
2012 Zhang H, You Y, Chen Y, Zheng X, Meltzer SJ. Abstract 4100: Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients Cancer Research. 72: 4100-4100. DOI: 10.1158/1538-7445.Am2012-4100  0.403
2012 Jain S, Chen S, Lin SY, Boldbaatar B, Xie L, Chang T, Hu C, Hamilton JP, Evans AA, Song W, Meltzer SJ, Block TM, Su Y. Abstract 4086: Location matters: The impact of the location of CpG sites on the specificity of methylation biomarkers for HCC Cancer Research. 72: 4086-4086. DOI: 10.1158/1538-7445.Am2012-4086  0.349
2012 Yang X, Wu W, Margolies N, Song JH, Cheng Y, Meltzer SJ. Abstract 190: Long noncoding RNA XY11-10-11 regulates proliferation and migration of esophageal adenocarcinoma cells Cancer Research. 72: 190-190. DOI: 10.1158/1538-7445.Am2012-190  0.42
2011 Jain S, Chang TT, Hamilton JP, Lin SY, Lin YJ, Evans AA, Selaru FM, Lin PW, Chen SH, Block TM, Hu CT, Song W, Meltzer SJ, Su YH. Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma. Plos One. 6: e26799. PMID 22073196 DOI: 10.1371/Journal.Pone.0026799  0.343
2011 David S, Meltzer SJ. MicroRNA involvement in esophageal carcinogenesis. Current Opinion in Pharmacology. 11: 612-6. PMID 21992930 DOI: 10.1016/J.Coph.2011.09.006  0.328
2011 Orloff M, Peterson C, He X, Ganapathi S, Heald B, Yang YR, Bebek G, Romigh T, Song JH, Wu W, David S, Cheng Y, Meltzer SJ, Eng C. Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma. Jama. 306: 410-9. PMID 21791690 DOI: 10.1001/Jama.2011.1029  0.382
2011 Mori Y, Olaru AV, Cheng Y, Agarwal R, Yang J, Luvsanjav D, Yu W, Selaru FM, Hutfless S, Lazarev M, Kwon JH, Brant SR, Marohn MR, Hutcheon DF, Duncan MD, ... ... Meltzer SJ, et al. Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning. Endocrine-Related Cancer. 18: 465-78. PMID 21636702 DOI: 10.1530/Erc-11-0083  0.358
2011 Yoon HH, Catalano PJ, Murphy KM, Skaar TC, Philips S, Powell M, Montgomery EA, Hafez MJ, Offer SM, Liu G, Meltzer SJ, Wu X, Forastiere AA, Benson AB, Kleinberg LR, et al. Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group. Bmc Cancer. 11: 176. PMID 21586140 DOI: 10.1186/1471-2407-11-176  0.311
2011 Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, ... ... Meltzer SJ, ... ... Meltzer S, et al. Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis. Plos Genetics. 7: e1001356. PMID 21483804 DOI: 10.1371/Journal.Pgen.1001356  0.423
2011 Ito T, Sato F, Kan T, Cheng Y, David S, Agarwal R, Paun BC, Jin Z, Olaru AV, Hamilton JP, Selaru FM, Yang J, Matsumura N, Shimizu K, Abraham JM, ... ... Meltzer SJ, et al. Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer. International Journal of Cancer. Journal International Du Cancer. 129: 2134-46. PMID 21170987 DOI: 10.1002/Ijc.25874  0.326
2011 Jin Z, Selaru FM, Cheng Y, Kan T, Agarwal R, Mori Y, Olaru AV, Yang J, David S, Hamilton JP, Abraham JM, Harmon J, Duncan M, Montgomery EA, Meltzer SJ. MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. Oncogene. 30: 1577-85. PMID 21119604 DOI: 10.1038/Onc.2010.534  0.432
2011 Wang L, Bi X, Pohl N, Cheng Y, Zhou Y, Shears S, Wang S, Xu X, Huang P, Chen Z, Wang L, Hong J, Xie H, Wei Q, Meltzer S, et al. Abstract 4704: A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis Cancer Research. 71: 4704-4704. DOI: 10.1158/1538-7445.Am2011-4704  0.409
2011 Guerrero-Preston R, Soudry E, Jaffe A, Ili-Gangas C, Brebi-Mieville P, Pérez J, Zhong X, Yang Q, Meltzer SJ, Esteller M, Sidransky D. Abstract 3172: Methylation portraits discriminate between hepatocellular carcinoma cases and controls Cancer Research. 71: 3172-3172. DOI: 10.1158/1538-7445.Am2011-3172  0.354
2011 Jankowski JA, Vakil NB, Ferguson MK, Bennett C, Moayyedi P, Bergman JJ, Harrison RF, Barr H, deCaestecker J, Inadomi JM, Shaheen NJ, Meltzer SJ, Fennerty MB, Waxman I, Ragunath K, et al. Barrett's Dysplasia Cancer Task Force – Bad Cat: A Global, Multidisciplinary, Consensus on the Management of High Grade Dysplasia and Early Mucosal Cancer in Barrett's Esophagus Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60721-X  0.306
2011 Olaru A, Cheng Y, Agarwal R, Abraham JM, David S, Kwon JH, Lazarev M, Brant SR, Duncan M, Goel A, Meltzer SJ, Mori Y. DNA Methylation Microarray Identifies Novel Methylation Biomarkers for Colorectal Cancer Detection Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60162-5  0.352
2010 Kashyap MK, Marimuthu A, Peri S, Kumar GS, Jacob HK, Prasad TS, Mahmood R, Kumar KV, Kumar MV, Meltzer SJ, Montgomery EA, Kumar RV, Pandey A. Overexpression of periostin and lumican in esophageal squamous cell carcinoma. Cancers. 2: 133-42. PMID 24281036 DOI: 10.3390/Cancers2010133  0.416
2010 David S, Meltzer SJ. Stomach - Genetic and epigenetic alterations of preneoplastic and neoplastic lesions. Cancer Biomarkers : Section a of Disease Markers. 9: 493-507. PMID 22112492 DOI: 10.3233/Cbm-2011-0169  0.397
2010 Kashyap MK, Harsha HC, Renuse S, Pawar H, Sahasrabuddhe NA, Kim MS, Marimuthu A, Keerthikumar S, Muthusamy B, Kandasamy K, Subbannayya Y, Prasad TS, Mahmood R, Chaerkady R, Meltzer SJ, et al. SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biology & Therapy. 10: 796-810. PMID 20686364 DOI: 10.4161/Cbt.10.8.12914  0.328
2010 Paun BC, Kukuruga D, Jin Z, Mori Y, Cheng Y, Duncan M, Stass SA, Montgomery E, Hutcheon D, Meltzer SJ. Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. Cancer. 116: 4495-501. PMID 20572039 DOI: 10.1002/Cncr.25348  0.373
2010 Agarwal R, Mori Y, Cheng Y, Jin Z, Olaru A, Hamilton JP, David S, Selaru FM, Yang J, Abraham J, Duncan M, Harmon J, Montgomery E, Morin PJ, Meltzer SJ. Abstract LB-89: Claudin-11 (CLDN11): A potential marker of gastric carcinogenesis Cellular and Molecular Biology. 70. DOI: 10.1158/1538-7445.Am10-Lb-89  0.335
2010 Gaston SM, Guerra AL, Nadadur RC, Meadows J, Kearney MC, Sorbara L, Srivastava S, Meltzer SJ, Pinsky P, Kearney GP. Abstract 3049: Overexpression of miR-17 family miRNAs in prostate cancer biopsies: Evidence for a stem-cell-like miRNA profile in high grade/high stage tumors Cancer Research. 70: 3049-3049. DOI: 10.1158/1538-7445.Am10-3049  0.301
2010 Olaru A, Luvsanjav D, Jin Z, Agarwal R, Cheng Y, David S, Montgomery EA, Meltzer SJ, Selaru F. M1911 Endothelin Receptor B (EDNRB) and MicroRNA-21 Expression in Gastric Cancer Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)62022-7  0.358
2009 Agarwal R, Mori Y, Cheng Y, Jin Z, Olaru AV, Hamilton JP, David S, Selaru FM, Yang J, Abraham JM, Montgomery E, Morin PJ, Meltzer SJ. Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. Plos One. 4: e8002. PMID 19956721 DOI: 10.1371/Journal.Pone.0008002  0.435
2009 Paun BC, Cheng Y, Leggett BA, Young J, Meltzer SJ, Mori Y. Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors. Plos One. 4: e7715. PMID 19888451 DOI: 10.1371/Journal.Pone.0007715  0.39
2009 Akagi T, Ito T, Kato M, Jin Z, Cheng Y, Kan T, Yamamoto G, Olaru A, Kawamata N, Boult J, Soukiasian HJ, Miller CW, Ogawa S, Meltzer SJ, Koeffler HP. Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. International Journal of Cancer. Journal International Du Cancer. 125: 2349-59. PMID 19670330 DOI: 10.1002/Ijc.24620  0.364
2009 Selaru FM, David S, Meltzer SJ, Hamilton JP. Epigenetic events in gastrointestinal cancer. The American Journal of Gastroenterology. 104: 1910-2. PMID 19661933 DOI: 10.1038/Ajg.2008.145  0.39
2009 David S, Mori Y, Paun BC, Olaru A, Kan T, Selaru FM, Cheng Y, Jin Z, Yang J, Agarwal R, Hamilton JP, Abraham JM, Meltzer SJ. T1926 Comparative Tumor-Suppressive Effects of Curcumin, Resveratrol and Quercetin in Esophageal Adenocarcinoma Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)62774-8  0.303
2009 Selaru FM, Paun BC, Hamilton JP, Olaru A, Cheng Y, Kan T, Abraham JM, Agarwal R, Yang J, David S, Mori Y, Jin Z, Gores GJ, Kwon JH, Meltzer SJ. 149 Tissue Inhibitor of Metalloproteinases 3 (TIMP3) Regulation in Cholangiocarcinoma By MicroRNA-21 and Promoter Hypermethylation Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60132-3  0.309
2008 Jin Z, Cheng Y, Olaru A, Kan T, Yang J, Paun B, Ito T, Hamilton JP, David S, Agarwal R, Selaru FM, Sato F, Abraham JM, Beer DG, Mori Y, ... ... Meltzer SJ, et al. Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors. International Journal of Cancer. Journal International Du Cancer. 123: 2331-6. PMID 18729198 DOI: 10.1002/Ijc.23804  0.4
2008 Abraham JM, Cheng Y, Hamilton JP, Paun B, Jin Z, Agarwal R, Kan T, David S, Olaru A, Yang J, Ito T, Selaru FM, Mori Y, Meltzer SJ. Generation of small 32P-labeled peptides as a potential approach to colorectal cancer therapy. Plos One. 3: e2508. PMID 18575578 DOI: 10.1371/Journal.Pone.0002508  0.331
2008 Ito T, Shimada Y, Kan T, David S, Cheng Y, Mori Y, Agarwal R, Paun B, Jin Z, Olaru A, Hamilton JP, Yang J, Abraham JM, Meltzer SJ, Sato F. Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma. Cancer Research. 68: 3214-24. PMID 18451147 DOI: 10.1158/0008-5472.Can-07-3043  0.392
2008 Jin Z, Hamilton JP, Yang J, Mori Y, Olaru A, Sato F, Ito T, Kan T, Cheng Y, Paun B, David S, Beer DG, Agarwal R, Abraham JM, Meltzer SJ. Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 111-7. PMID 18199717 DOI: 10.1158/1055-9965.Epi-07-0407  0.437
2008 Jin Z, Mori Y, Hamilton JP, Olaru A, Sato F, Yang J, Ito T, Kan T, Agarwal R, Meltzer SJ. Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis. Cancer. 112: 43-9. PMID 17999418 DOI: 10.1002/Cncr.23135  0.43
2008 Jin Z, Cheng Y, Hamilton JP, Mori Y, Olaru A, Ito T, Kang K, Paun BC, David S, Yang J, Agarwal R, Abraham JM, Meltzer SJ. M1979 Hypermethylation of the AKAP12 Promoter in Human Esophageal Cancer Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62072-7  0.342
2007 Ito T, Tanaka E, Kadowaki T, Kan T, Higashiyama M, Shiojima S, Tomoda S, Myoumoto A, Akiyama H, Nobumasa H, Matsumoto S, Miyamoto S, Mitsumori M, Sato F, Watanabe G, ... ... Meltzer SJ, et al. An ultrasensitive new DNA microarray chip provides gene expression profiles for preoperative esophageal cancer biopsies without RNA amplification. Oncology. 73: 366-75. PMID 18511875 DOI: 10.1159/000136156  0.371
2007 Selaru FM, Wang S, Yin J, Schulmann K, Xu Y, Mori Y, Olaru AV, Sato F, Hamilton JP, Abraham JM, Schneider P, Greenwald BD, Brabender J, Meltzer SJ. Beyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma. Bioinformatics and Biology Insights. 1: 127-136. PMID 18425214 DOI: 10.4137/Bbi.S311  0.383
2007 Kan T, Paun BC, Mori Y, Sato F, Jin Z, Hamilton JP, Ito T, Cheng Y, David S, Olaru AV, Yang J, Agarwal R, Abraham JM, Meltzer SJ. Rarity of Somatic Mutation and Frequency of Normal Sequence Variation Detected in Sporadic Colon Adenocarcinoma Using High-Throughput cDNA Sequencing. Bioinformatics and Biology Insights. 1: 1-16. PMID 18389087 DOI: 10.4137/Bbi.S0  0.378
2007 Jin Z, Olaru A, Yang J, Sato F, Cheng Y, Kan T, Mori Y, Mantzur C, Paun B, Hamilton JP, Ito T, Wang S, David S, Agarwal R, Beer DG, ... ... Meltzer SJ, et al. Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6293-300. PMID 17975140 DOI: 10.1158/1078-0432.Ccr-07-0818  0.397
2007 Abraham JM, Sato F, Cheng Y, Paun B, Kan T, Olaru A, Jin Z, Yang J, Agarwal R, David S, Hamilton JP, Ito T, Mori Y, Meltzer SJ. Novel decapeptides that bind avidly and deliver radioisotope to colon cancer cells. Plos One. 2: e964. PMID 17912343 DOI: 10.1371/Journal.Pone.0000964  0.359
2007 Kanner WA, Drachenberg CB, Papadimitriou JC, Wang S, Meltzer SJ, Sklar GN. Urethral stromal tumor with pacemaker cell phenotype. Ultrastructural Pathology. 31: 63-71. PMID 17455099 DOI: 10.1080/01913120601172299  0.331
2007 Jin Z, Mori Y, Yang J, Sato F, Ito T, Cheng Y, Paun B, Hamilton JP, Kan T, Olaru A, David S, Agarwal R, Abraham JM, Beer D, Montgomery E, ... Meltzer SJ, et al. Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. Oncogene. 26: 6332-40. PMID 17452981 DOI: 10.1038/Sj.Onc.1210461  0.379
2007 Konishi K, Shen L, Wang S, Meltzer SJ, Harpaz N, Issa JP. Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology. 132: 1254-60. PMID 17408633 DOI: 10.1053/J.Gastro.2007.01.035  0.349
2006 Hamilton JP, Sato F, Jin Z, Greenwald BD, Ito T, Mori Y, Paun BC, Kan T, Cheng Y, Wang S, Yang J, Abraham JM, Meltzer SJ. Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6637-42. PMID 17121882 DOI: 10.1158/1078-0432.Ccr-06-1781  0.41
2006 Mori Y, Cai K, Cheng Y, Wang S, Paun B, Hamilton JP, Jin Z, Sato F, Berki AT, Kan T, Ito T, Mantzur C, Abraham JM, Meltzer SJ. A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer. Gastroenterology. 131: 797-808. PMID 16952549 DOI: 10.1053/J.Gastro.2006.06.006  0.429
2006 Sterian A, Kan T, Berki AT, Mori Y, Olaru A, Schulmann K, Sato F, Wang S, Paun B, Cai K, Hamilton JP, Abraham JM, Meltzer SJ. Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma. Oncology. 70: 168-72. PMID 16837775 DOI: 10.1159/000094444  0.366
2006 O'Neill JP, Velalar CN, Lee DI, Zhang B, Nakanishi T, Tang Y, Selaru F, Ross D, Meltzer SJ, Hussain A. Thapsigargin resistance in human prostate cancer cells. Cancer. 107: 649-59. PMID 16770788 DOI: 10.1002/Cncr.22027  0.306
2006 Hamilton JP, Sato F, Greenwald BD, Suntharalingam M, Krasna MJ, Edelman MJ, Doyle A, Berki AT, Abraham JM, Mori Y, Kan T, Mantzur C, Paun B, Wang S, Ito T, ... ... Meltzer SJ, et al. Promoter methylation and response to chemotherapy and radiation in esophageal cancer. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 4: 701-8. PMID 16678495 DOI: 10.1016/J.Cgh.2006.03.007  0.367
2006 Hamilton JP, Meltzer SJ. A review of the genomics of gastric cancer. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 4: 416-25. PMID 16616344 DOI: 10.1016/J.Cgh.2006.01.019  0.415
2006 Shibata D, Mori Y, Cai K, Zhang L, Yin J, Elahi A, Hamelin R, Wong YF, Lo WK, Chung TK, Sato F, Karpeh MS, Meltzer SJ. RAB32 hypermethylation and microsatellite instability in gastric and endometrial adenocarcinomas. International Journal of Cancer. Journal International Du Cancer. 119: 801-6. PMID 16557577 DOI: 10.1002/Ijc.21912  0.463
2006 Sato F, Abraham JM, Yin J, Kan T, Ito T, Mori Y, Hamilton JP, Jin Z, Cheng Y, Paun B, Berki AT, Wang S, Shimada Y, Meltzer SJ. Polo-like kinase and survivin are esophageal tumor-specific promoters. Biochemical and Biophysical Research Communications. 342: 465-71. PMID 16487489 DOI: 10.1016/J.Bbrc.2006.01.177  0.41
2006 Wang S, Zhan M, Yin J, Abraham JM, Mori Y, Sato F, Xu Y, Olaru A, Berki AT, Li H, Schulmann K, Kan T, Hamilton JP, Paun B, Yu MM, ... ... Meltzer SJ, et al. Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis. Oncogene. 25: 3346-56. PMID 16449976 DOI: 10.1038/Sj.Onc.1209357  0.389
2006 Kan T, Yamasaki S, Kondo K, Teratani N, Kawabe A, Kaganoi J, Meltzer SJ, Imamura M, Shimada Y. A new specific gene expression in squamous cell carcinoma of the esophagus detected using representational difference analysis and cDNA microarray. Oncology. 70: 25-33. PMID 16446548 DOI: 10.1159/000091183  0.372
2006 Sato F, Meltzer SJ. CpG island hypermethylation in progression of esophageal and gastric cancer. Cancer. 106: 483-93. PMID 16362978 DOI: 10.1002/cncr.21657  0.324
2006 Takahashi T, Shigematsu H, Shivapurkar N, Reddy J, Zheng Y, Feng Z, Suzuki M, Nomura M, Augustus M, Yin J, Meltzer SJ, Gazdar AF. Aberrant promoter methylation of multiple genes during multistep pathogenesis of colorectal cancers. International Journal of Cancer. Journal International Du Cancer. 118: 924-31. PMID 16108009 DOI: 10.1002/Ijc.21453  0.385
2005 Brabender J, Marjoram P, Lord RV, Metzger R, Salonga D, Vallböhmer D, Schäfer H, Danenberg KD, Danenberg PV, Selaru FM, Baldus SE, Hölscher AH, Meltzer SJ, Schneider PM. The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophagus and patients with Barrett's-associated adenocarcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2113-7. PMID 16172218 DOI: 10.1158/1055-9965.Epi-05-0014  0.341
2005 Schulmann K, Mori Y, Croog V, Yin J, Olaru A, Sterian A, Sato F, Wang S, Xu Y, Deacu E, Berki AT, Hamilton JP, Kan T, Abraham JM, Schmiegel W, ... ... Meltzer SJ, et al. Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability. Gastroenterology. 129: 74-85. PMID 16012936 DOI: 10.1053/J.Gastro.2005.04.011  0.35
2005 Schulmann K, Sterian A, Berki A, Yin J, Sato F, Xu Y, Olaru A, Wang S, Mori Y, Deacu E, Hamilton J, Kan T, Krasna MJ, Beer DG, Pepe MS, ... ... Meltzer SJ, et al. Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene. 24: 4138-48. PMID 15824739 DOI: 10.1038/Sj.Onc.1208598  0.333
2005 Schulmann K, Brasch FE, Kunstmann E, Engel C, Pagenstecher C, Vogelsang H, Krüger S, Vogel T, Knaebel HP, Rüschoff J, Hahn SA, Knebel-Doeberitz MV, Moeslein G, Meltzer SJ, Schackert HK, et al. HNPCC-associated small bowel cancer: clinical and molecular characteristics. Gastroenterology. 128: 590-9. PMID 15765394 DOI: 10.1053/J.Gastro.2004.12.051  0.355
2005 Takahashi T, Suzuki M, Shigematsu H, Shivapurkar N, Echebiri C, Nomura M, Stastny V, Augustus M, Wu CW, Wistuba II, Meltzer SJ, Gazdar AF. Aberrant methylation of Reprimo in human malignancies. International Journal of Cancer. Journal International Du Cancer. 115: 503-10. PMID 15700311 DOI: 10.1002/Ijc.20910  0.465
2005 Sati F, Abraham JM, Yin J, Kan T, Mori Y, Meltzer SJ. 325. Identification of Genes Expressed Specifically in Esophageal Cancer Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.328  0.459
2004 Xu H, Chaturvedi R, Cheng Y, Bussiere FI, Asim M, Yao MD, Potosky D, Meltzer SJ, Rhee JG, Kim SS, Moss SF, Hacker A, Wang Y, Casero RA, Wilson KT. Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis. Cancer Research. 64: 8521-5. PMID 15574757 DOI: 10.1158/0008-5472.Can-04-3511  0.349
2004 Deacu E, Mori Y, Sato F, Yin J, Olaru A, Sterian A, Xu Y, Wang S, Schulmann K, Berki A, Kan T, Abraham JM, Meltzer SJ. Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes. Cancer Research. 64: 7690-6. PMID 15520171 DOI: 10.1158/0008-5472.Can-04-2082  0.406
2004 Kimos MC, Wang S, Borkowski A, Yang GY, Yang CS, Perry K, Olaru A, Deacu E, Sterian A, Cottrell J, Papadimitriou J, Sisodia L, Selaru FM, Mori Y, Xu Y, ... ... Meltzer SJ, et al. Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression. International Journal of Cancer. Journal International Du Cancer. 111: 415-7. PMID 15221970 DOI: 10.1002/Ijc.20267  0.366
2004 Ma X, Yang Q, Wilson KT, Kundu N, Meltzer SJ, Fulton AM. Promoter methylation regulates cyclooxygenase expression in breast cancer. Breast Cancer Research : Bcr. 6: R316-21. PMID 15217498 DOI: 10.1186/Bcr793  0.398
2004 Stokes NR, Zhou X, Meltzer SJ, Kaper JB. Transcriptional responses of intestinal epithelial cells to infection with Vibrio cholerae. Infection and Immunity. 72: 4240-8. PMID 15213169 DOI: 10.1128/Iai.72.7.4240-4248.2004  0.328
2004 Brabender J, Marjoram P, Salonga D, Metzger R, Schneider PM, Park JM, Schneider S, Hölscher AH, Yin J, Meltzer SJ, Danenberg KD, Danenberg PV, Lord RV. A multigene expression panel for the molecular diagnosis of Barrett's esophagus and Barrett's adenocarcinoma of the esophagus. Oncogene. 23: 4780-8. PMID 15107828 DOI: 10.1038/Sj.Onc.1207663  0.35
2004 Mori Y, Yin J, Sato F, Sterian A, Simms LA, Selaru FM, Schulmann K, Xu Y, Olaru A, Wang S, Deacu E, Abraham JM, Young J, Leggett BA, Meltzer SJ. Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning. Cancer Research. 64: 2434-8. PMID 15059896 DOI: 10.1158/0008-5472.Can-03-3508  0.436
2003 Olaru A, Mori Y, Yin J, Wang S, Kimos MC, Perry K, Xu Y, Sato F, Selaru FM, Deacu E, Sterian A, Shibata D, Abraham JM, Meltzer SJ. Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 1867-71. PMID 14691305 DOI: 10.1097/01.Lab.0000106723.75567.72  0.418
2003 Wang S, Mori Y, Sato F, Yin J, Xu Y, Zou TT, Olaru A, Kimos MC, Perry K, Selaru FM, Deacu E, Sun M, Shi YC, Shibata D, Abraham JM, ... ... Meltzer SJ, et al. An LOH and mutational investigation of the ST7 gene locus in human esophageal carcinoma. Oncogene. 22: 467-70. PMID 12545169 DOI: 10.1038/Sj.Onc.1206125  0.389
2003 Deacu E, Mori Y, Sato F, Selaru FM, Olaru A, Yin J, Wang S, Xu Y, Liu TC, Shibata D, Abraham JM, Meltzer SJ. Integrated gene expression profiling and in silico epigenomic scanning to identify genes involved in microsatellite instability status of colorectal carcinoma Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80063-X  0.454
2002 Yamashita K, Upadhyay S, Osada M, Hoque MO, Xiao Y, Mori M, Sato F, Meltzer SJ, Sidransky D. Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell. 2: 485-95. PMID 12498717 DOI: 10.1016/S1535-6108(02)00215-5  0.447
2002 Sato F, Shibata D, Harpaz N, Xu Y, Yin J, Mori Y, Wang S, Olaru A, Deacu E, Selaru FM, Kimos MC, Hytiroglou P, Young J, Leggett B, Gazdar AF, ... ... Meltzer SJ, et al. Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma. Cancer Research. 62: 6820-2. PMID 12460892  0.326
2002 Shibata DM, Sato F, Mori Y, Perry K, Yin J, Wang S, Xu Y, Olaru A, Selaru F, Spring K, Young J, Abraham JM, Meltzer SJ. Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas. Cancer Research. 62: 5637-40. PMID 12384516  0.33
2002 Zou TT, Selaru FM, Xu Y, Shustova V, Yin J, Mori Y, Shibata D, Sato F, Wang S, Olaru A, Deacu E, Liu TC, Abraham JM, Meltzer SJ. Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon. Oncogene. 21: 4855-62. PMID 12101425 DOI: 10.1038/Sj.Onc.1205613  0.433
2002 Mori Y, Sato F, Selaru FM, Olaru A, Perry K, Kimos MC, Tamura G, Matsubara N, Wang S, Xu Y, Yin J, Zou TT, Leggett B, Young J, Nukiwa T, ... ... Meltzer SJ, et al. Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers. Cancer Research. 62: 3641-5. PMID 12097267  0.354
2002 Toyooka S, Toyooka KO, Harada K, Miyajima K, Makarla P, Sathyanarayana UG, Yin J, Sato F, Shivapurkar N, Meltzer SJ, Gazdar AF. Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas. Cancer Research. 62: 3382-6. PMID 12067979  0.305
2002 Smolinski KN, Abraham JM, Souza RF, Yin J, Wang S, Xu Y, Zou TT, Kong D, Fleisher AS, Meltzer SJ. Activation of the esophagin promoter during esophageal epithelial cell differentiation. Genomics. 79: 875-80. PMID 12036303 DOI: 10.1006/Geno.2002.6775  0.783
2002 Sato K, Tamura G, Tsuchiya T, Endoh Y, Sakata K, Motoyama T, Usuba O, Kimura W, Terashima M, Nishizuka S, Zou T, Meltzer SJ. Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer. Virchows Archiv : An International Journal of Pathology. 440: 160-5. PMID 11964046 DOI: 10.1007/S004280100499  0.497
2002 Selaru FM, Xu Y, Yin J, Zou T, Liu TC, Mori Y, Abraham JM, Sato F, Wang S, Twigg C, Olaru A, Shustova V, Leytin A, Hytiroglou P, Shibata D, ... ... Meltzer SJ, et al. Artificial neural networks distinguish among subtypes of neoplastic colorectal lesions. Gastroenterology. 122: 606-13. PMID 11874992 DOI: 10.1053/Gast.2002.31904  0.333
2002 Selaru FM, Zou T, Xu Y, Shustova V, Yin J, Mori Y, Sato F, Wang S, Olaru A, Shibata D, Greenwald BD, Krasna MJ, Abraham JM, Meltzer SJ. Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays. Oncogene. 21: 475-8. PMID 11821959 DOI: 10.1038/Sj.Onc.1205111  0.355
2001 Trojan J, Plotz G, Brieger A, Raedle J, Meltzer SJ, Wolter M, Zeuzem S. Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease. The Journal of Investigative Dermatology. 117: 1650-3. PMID 11886535 DOI: 10.1046/J.0022-202X.2001.01954.X  0.3
2001 Umansky M, Yasui W, Hallak A, Brill S, Shapira I, Halpern Z, Hibshoosh H, Rattan J, Meltzer S, Tahara E, Arber N. Proton pump inhibitors reduce cell cycle abnormalities in Barrett's esophagus. Oncogene. 20: 7987-91. PMID 11753681 DOI: 10.1038/Sj.Onc.1204947  0.341
2001 Takashima H, Matsumoto Y, Matsubara N, Shirakawa Y, Kawashima R, Tanino M, Ito S, Isozaki H, Ouchida M, Meltzer SJ, Shimizu K, Tanaka N. Effect of naturally occurring E2F-4 alterations on transcriptional activation and proliferation in transfected cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 81: 1565-73. PMID 11706064 DOI: 10.1038/Labinvest.3780370  0.425
2001 Brabender J, Usadel H, Danenberg KD, Metzger R, Schneider PM, Lord RV, Wickramasinghe K, Lum CE, Park J, Salonga D, Singer J, Sidransky D, Hölscher AH, Meltzer SJ, Danenberg PV. Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival. Oncogene. 20: 3528-32. PMID 11429699 DOI: 10.1038/Sj.Onc.1204455  0.388
2001 Fleisher AS, Esteller M, Tamura G, Rashid A, Stine OC, Yin J, Zou TT, Abraham JM, Kong D, Nishizuka S, James SP, Wilson KT, Herman JG, Meltzer SJ. Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia. Oncogene. 20: 329-35. PMID 11313962 DOI: 10.1038/Sj.Onc.1204104  0.78
2000 Kawakami K, Brabender J, Lord RV, Groshen S, Greenwald BD, Krasna MJ, Yin J, Fleisher AS, Abraham JM, Beer DG, Sidransky D, Huss HT, Demeester TR, Eads C, Laird PW, ... ... Meltzer SJ, et al. Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. Journal of the National Cancer Institute. 92: 1805-11. PMID 11078757 DOI: 10.1093/Jnci/92.22.1805  0.451
2000 Hardy RG, Meltzer SJ, Jankowski JA. ABC of colorectal cancer. Molecular basis for risk factors. Bmj (Clinical Research Ed.). 321: 886-9. PMID 11021873 DOI: 10.1136/Bmj.321.7265.886  0.418
2000 Fleisher AS, Esteller M, Harpaz N, Leytin A, Rashid A, Xu Y, Liang J, Stine OC, Yin J, Zou TT, Abraham JM, Kong D, Wilson KT, James SP, Herman JG, ... Meltzer SJ, et al. Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Research. 60: 4864-8. PMID 10987299  0.754
2000 Tsuchiya T, Tamura G, Sato K, Endoh Y, Sakata K, Jin Z, Motoyama T, Usuba O, Kimura W, Nishizuka S, Wilson KT, James SP, Yin J, Fleisher AS, Zou T, ... ... Meltzer SJ, et al. Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia. Oncogene. 19: 3642-6. PMID 10951570 DOI: 10.1038/Sj.Onc.1203704  0.777
2000 Simms LA, Young J, Wicking C, Meltzer SJ, Jass JR, Leggett BA. The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers. Cell Death and Differentiation. 7: 236-7. PMID 10819599 DOI: 10.1038/Sj.Cdd.4400650  0.394
2000 Fleisher AS, Meltzer SJ, James SP. Colon polyps in Beckwith-Wiedmann syndrome: role of imprinted genes. Gastroenterology. 118: 637. PMID 10755868 DOI: 10.1016/S0016-5085(00)70277-0  0.306
2000 Tamura G, Yin J, Wang S, Fleisher AS, Zou T, Abraham JM, Kong D, Smolinski KN, Wilson KT, James SP, Silverberg SG, Nishizuka S, Terashima M, Motoyama T, Meltzer SJ. E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas. Journal of the National Cancer Institute. 92: 569-73. PMID 10749913 DOI: 10.1093/Jnci/92.7.569  0.788
2000 Akhtar M, Magno RM, Yin J, Xu Y, Meltzer SJ, Wilson KT. Promoter demethylation by 5-Azacytidjne upregulates cyclooxygenase-2 expression in gastric epithelial cells Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85168-9  0.385
2000 Steven Fleisher A, Esteller M, Rashid A, Yin J, Zou T, Kong D, Abraham JM, Colin Stein O, James SP, Herman JG, Harpaz N, Meltzer SJ. Microsatellite instability in IBD-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, HMLH1 Gastroenterology. 118: A706-A707. DOI: 10.1016/S0016-5085(00)84957-4  0.735
2000 Akhtar M, Magno RM, Yin J, Yu X, Ashktorab H, Smoot DT, Meltzer SJ, Wilson KT. Upregulation of signal transduction and pro-neoplastic genes and downregulation of antiapoptotic and cytoprotective genes in H.pylori-stimulated gastric epithelial cells Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82766-3  0.369
2000 Akhtar M, Magno RM, Yin J, Fleisher AS, Tamura G, Meltzer SJ, Wilson KT. Hypomethylation of the cyclooxygenase-2 promoter in gastric adenocarcinomas with microsatellite instability Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82280-5  0.367
1999 Krasna MJ, Mao YS, Sonett JR, Tamura G, Jones R, Suntharalingam M, Meltzer SJ. P53 gene protein overexpression predicts results of trimodality therapy in esophageal cancer patients. The Annals of Thoracic Surgery. 68: 2021-4; discussion 2. PMID 10616970 DOI: 10.1016/S0003-4975(99)01146-7  0.362
1999 Jass JR, Biden KG, Cummings MC, Simms LA, Walsh M, Schoch E, Meltzer SJ, Wright C, Searle J, Young J, Leggett BA. Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology. 52: 455-60. PMID 10562815 DOI: 10.1136/Jcp.52.6.455  0.366
1999 Yin J, Harpaz N, Souza RF, Zou T, Kong D, Wang S, Leytin AL, Medalie NS, Smolinski KN, Abraham JM, Fleisher AS, Meltzer SJ. Low prevalence of the APC I1307K sequence in Jewish and non-Jewish patients with inflammatory bowel disease. Oncogene. 18: 3902-4. PMID 10445854 DOI: 10.1038/Sj.Onc.1202638  0.784
1999 Sheikh MS, Huang Y, Fernandez-Salas EA, El-Deiry WS, Friess H, Amundson S, Yin J, Meltzer SJ, Holbrook NJ, Fornace AJ. The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract. Oncogene. 18: 4153-9. PMID 10435597 DOI: 10.1038/Sj.Onc.1202763  0.369
1999 Souza RF, Wang S, Thakar M, Smolinski KN, Yin J, Zou TT, Kong D, Abraham JM, Toretsky JA, Meltzer SJ. Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells. Oncogene. 18: 4063-8. PMID 10435587 DOI: 10.1038/Sj.Onc.1202768  0.801
1999 Fu S, Ramanujam KS, Wong A, Fantry GT, Drachenberg CB, James SP, Meltzer SJ, Wilson KT. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology. 116: 1319-29. PMID 10348815 DOI: 10.1016/S0016-5085(99)70496-8  0.352
1999 Jankowski JA, Wright NA, Meltzer SJ, Triadafilopoulos G, Geboes K, Casson AG, Kerr D, Young LS. Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. The American Journal of Pathology. 154: 965-73. PMID 10233832 DOI: 10.1016/S0002-9440(10)65346-1  0.351
1999 Fleisher AS, Esteller M, Wang S, Tamura G, Suzuki H, Yin J, Zou TT, Abraham JM, Kong D, Smolinski KN, Shi YQ, Rhyu MG, Powell SM, James SP, Wilson KT, ... ... Meltzer SJ, et al. Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Research. 59: 1090-5. PMID 10070967  0.817
1999 Biden KG, Simms LA, Cummings M, Buttenshaw R, Schoch E, Searle J, Gobe G, Jass JR, Meltzer SJ, Leggett BA, Young J. Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene. 18: 1245-9. PMID 10022131 DOI: 10.1038/Sj.Onc.1202413  0.374
1998 Zou T, Fleisher AS, Kong D, Yin J, Souza RF, Wang S, Smolinski KN, Abraham JM, Meltzer SJ. Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues. Cancer Research. 58: 4802-4. PMID 9809981  0.803
1998 Simms LA, Radford-Smith G, Biden KG, Buttenshaw R, Cummings M, Jass JR, Young J, Meltzer SJ, Leggett BA. Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers. Oncogene. 17: 2003-8. PMID 9788444 DOI: 10.1038/Sj.Onc.1202109  0.438
1998 Souza R, Wang S, Smolinski K, Yin J, Zou T, Kong D, Abraham J, Sly W, Meltzer S. The insulin-like growth factor II receptor: A potential growth suppressor gene in colorectal carcinoma cells Gastroenterology. 114: A682-A683. DOI: 10.1016/S0016-5085(98)82800-X  0.779
1997 Yin J, Kong D, Wang S, Zou TT, Souza RF, Smolinski KN, Lynch PM, Hamilton SR, Sugimura H, Powell SM, Young J, Abraham JM, Meltzer SJ. Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. Human Mutation. 10: 474-8. PMID 9401011 DOI: 10.1002/(Sici)1098-1004(1997)10:6<474::Aid-Humu9>3.0.Co;2-D  0.81
1997 Kong D, Suzuki A, Zou TT, Sakurada A, Kemp LW, Wakatsuki S, Yokoyama T, Yamakawa H, Furukawa T, Sato M, Ohuchi N, Sato S, Yin J, Wang S, Abraham JM, ... ... Meltzer SJ, et al. PTEN1 is frequently mutated in primary endometrial carcinomas. Nature Genetics. 17: 143-4. PMID 9326929 DOI: 10.1038/Ng1097-143  0.769
1997 Zou TT, Lei J, Shi YQ, Yin J, Wang S, Souza RF, Kong D, Shimada Y, Smolinski KN, Greenwald BD, Abraham JM, Harpaz N, Meltzer SJ. FHIT gene alterations in esophageal cancer and ulcerative colitis (UC). Oncogene. 15: 101-5. PMID 9233782 DOI: 10.1038/Sj.Onc.1201169  0.802
1997 Balcer-Kubiczek EK, Meltzer SJ, Han LH, Zhang XF, Shi ZM, Harrison GH, Abraham JM. Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells. Oncogene. 14: 3051-7. PMID 9223668 DOI: 10.1038/Sj.Onc.1201151  0.382
1997 Wang S, Souza RF, Kong D, Yin J, Smolinski KN, Zou TT, Frank T, Young J, Flanders KC, Sugimura H, Abraham JM, Meltzer SJ. Deficient transforming growth factor-beta1 activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors. Cancer Research. 57: 2543-6. PMID 9205049  0.774
1997 Souza RF, Yin J, Smolinski KN, Zou TT, Wang S, Shi YQ, Rhyu MG, Cottrell J, Abraham JM, Biden K, Simms L, Leggett B, Bova GS, Frank T, Powell SM, ... ... Meltzer SJ, et al. Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. Cancer Research. 57: 2350-3. PMID 9192806  0.781
1997 Simms LA, Zou TT, Young J, Shi YQ, Lei J, Appel R, Rhyu MG, Sugimura H, Chenevix-Trench G, Souza RF, Meltzer SJ, Leggett BA. Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers. Oncogene. 14: 2613-8. PMID 9191061 DOI: 10.1038/Sj.Onc.1201094  0.368
1997 Souza RF, Lei J, Yin J, Appel R, Zou TT, Zhou X, Wang S, Rhyu MG, Cymes K, Chan O, Park WS, Krasna MJ, Greenwald BD, Cottrell J, Abraham JM, ... ... Meltzer SJ, et al. A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms. Gastroenterology. 112: 40-5. PMID 8978341 DOI: 10.1016/S0016-5085(97)70217-8  0.422
1996 Balcer-Kubiczek EK, Zhang XF, Harrison GH, McCready WA, Shi ZM, Han LH, Abraham JM, Ampey LL, Meltzer SJ, Jacobs MC, Davis CC. Rodent cell transformation and immediate early gene expression following 60-Hz magnetic field exposure. Environmental Health Perspectives. 104: 1188-98. PMID 8959408 DOI: 10.1289/Ehp.961041188  0.315
1996 Lei J, Zou TT, Shi YQ, Zhou X, Smolinski KN, Yin J, Souza RF, Appel R, Wang S, Cymes K, Chan O, Abraham JM, Harpaz N, Meltzer SJ. Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms. Oncogene. 13: 2459-62. PMID 8957088  0.771
1996 Souza RF, Appel R, Yin J, Wang S, Smolinski KN, Abraham JM, Zou TT, Shi YQ, Lei J, Cottrell J, Cymes K, Biden K, Simms L, Leggett B, Lynch PM, ... ... Meltzer SJ, et al. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nature Genetics. 14: 255-7. PMID 8896552 DOI: 10.1038/Ng1196-255  0.74
1996 Souza RF, Appel R, Yin J, Wang S, Smolinski KN, Abraham JM, Zou T, Shi Y, Lei J, Cottrell J, Cymes K, Biden K, Simms L, Leggett B, Lynch PM, ... ... Meltzer SJ, et al. Erratum: Corrigendum: The insulin–like growth factor II receptor gene is a target of microsatellite instability in human gastrointestinal tumours Nature Genetics. 14: 488-488. DOI: 10.1038/Ng1296-488A  0.74
1995 Balcer-Kubiczek EK, Yin J, Lin K, Harrison GH, Abraham JM, Meltzer SJ. p53 mutational status and survival of human breast cancer MCF-7 cell variants after exposure to X rays or fission neutrons. Radiation Research. 142: 256-62. PMID 7761574 DOI: 10.2307/3579133  0.348
1995 Itzkowitz SH, Greenwald B, Meltzer SJ. Colon carcinogenesis in inflammatory bowel disease. Inflammatory Bowel Diseases. 1: 142-158. DOI: 10.1002/Ibd.3780010208  0.42
1994 Largey JS, Meltzer SJ, Sauk JJ, Hebert CA, Archibald DW. Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas. Oral Surgery, Oral Medicine, and Oral Pathology. 77: 260-3. PMID 8170656 DOI: 10.1016/0030-4220(94)90295-X  0.441
1994 Powell SM, Papadopoulos N, Kinzler KW, Smolinski KN, Meltzer SJ. APC gene mutations in the mutation cluster region are rare in esophageal cancers. Gastroenterology. 107: 1759-63. PMID 7958689 DOI: 10.1016/0016-5085(94)90818-4  0.756
1994 Togawa K, Jaskiewicz K, Takahashi H, Meltzer SJ, Rustgi AK. Human papillomavirus DNA sequences in esophagus squamous cell carcinoma. Gastroenterology. 107: 128-36. PMID 7912679 DOI: 10.1016/0016-5085(94)90070-1  0.378
1993 Yin J, Harpaz N, Tong Y, Huang Y, Laurin J, Greenwald BD, Hontanosas M, Newkirk C, Meltzer SJ. p53 point mutations in dysplastic and cancerous ulcerative colitis lesions. Gastroenterology. 104: 1633-9. PMID 8500720 DOI: 10.1016/0016-5085(93)90639-T  0.407
1993 Largey JS, Meltzer SJ, Yin J, Norris K, Sauk JJ, Archibald DW. Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction. Cancer. 71: 1933-7. PMID 8443743 DOI: 10.1002/1097-0142(19930315)71:6<1933::Aid-Cncr2820710602>3.0.Co;2-D  0.449
1992 Boynton RF, Blount PL, Yin J, Brown VL, Huang Y, Tong Y, McDaniel T, Newkirk C, Resau JH, Raskind WH, Haggitt RC, Reid BJ, Meltzer SJ. Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers. Proceedings of the National Academy of Sciences of the United States of America. 89: 3385-8. PMID 1565631 DOI: 10.1073/Pnas.89.8.3385  0.402
1991 Meltzer SJ, Yin J, Huang Y, McDaniel TK, Newkirk C, Iseri O, Vogelstein B, Resau JH. Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction. Proceedings of the National Academy of Sciences of the United States of America. 88: 4976-80. PMID 2052580 DOI: 10.1073/Pnas.88.11.4976  0.391
1990 Mane SM, Meltzer SJ, Gutheil JC, Kapil V, Lee EJ, Needleman SW. RAS gene activation in acute myelogenous leukemia: analysis by in vitro amplification and DNA base sequence determination. Genes, Chromosomes & Cancer. 2: 71-7. PMID 2278967 DOI: 10.1002/Gcc.2870020113  0.334
Low-probability matches (unlikely to be authored by this person)
2008 Ito T, Sato F, Kang K, David S, Cheng Y, Mori Y, Agarwal R, Paun BC, Jin Z, Olaru A, Hamilton JP, Selaru FM, Yang J, Shimada Y, Abraham JM, ... Meltzer SJ, et al. M2005 Down-Regulation of PTTG1 By siRNA Suppresses Tumorigenesis and Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma In Vivo Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62098-3  0.3
2009 Kan T, Meltzer SJ. MicroRNAs in Barrett's esophagus and esophageal adenocarcinoma. Current Opinion in Pharmacology. 9: 727-32. PMID 19773200 DOI: 10.1016/J.Coph.2009.08.009  0.3
2016 Peng Y, Zhang X, Ma Q, Yan R, Qin Y, Zhao Y, Cheng Y, Yang M, Wang Q, Feng X, Huang Y, Huang W, Zhao Z, Wang L, Wei Y, ... ... Meltzer SJ, et al. MiRNA-194 activates the Wnt/β-catenin signaling pathway in gastric cancer by targeting the negative Wnt regulator, SUFU. Cancer Letters. PMID 27810403 DOI: 10.1016/J.Canlet.2016.10.035  0.299
1996 Wilson KT, Ramanujam KS, Mobley HL, Musselman RF, James SP, Meltzer SJ. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology. 111: 1524-33. PMID 8942731 DOI: 10.1016/S0016-5085(96)70014-8  0.298
2011 Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, Cuatrecasas M, Arnold M, Meltzer SJ, Syngal S, Stoffel E, Jover R, Llor X, Castells A, Boland CR, et al. Colorectal cancers with microsatellite instability display unique miRNA profiles. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6239-49. PMID 21844009 DOI: 10.1158/1078-0432.Ccr-11-1424  0.295
2004 Selaru FM, Yin J, Olaru A, Mori Y, Xu Y, Epstein SH, Sato F, Deacu E, Wang S, Sterian A, Fulton A, Abraham JM, Shibata D, Baquet C, Stass SA, ... Meltzer SJ, et al. An unsupervised approach to identify molecular phenotypic components influencing breast cancer features. Cancer Research. 64: 1584-8. PMID 14996713 DOI: 10.1158/0008-5472.Can-03-3208  0.295
2011 Cheng Y, Yang J, Agarwal R, Green GM, Mease RC, Pomper MG, Meltzer SJ, Abraham JM. Strong inhibition of xenografted tumor growth by low-level doses of [(32)P]ATP. Oncotarget. 2: 461-6. PMID 21646686 DOI: 10.18632/Oncotarget.289  0.291
2001 Souza RF, Meltzer SJ. Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas. Methods in Molecular Medicine. 50: 137-48. PMID 21318823 DOI: 10.1385/1-59259-084-5:137  0.291
2004 McManus DT, Olaru A, Meltzer SJ. Biomarkers of esophageal adenocarcinoma and Barrett's esophagus. Cancer Research. 64: 1561-9. PMID 14996709 DOI: 10.1158/0008-5472.Can-03-2438  0.291
2020 Kambhampati S, Tieu AH, Luber B, Wang H, Meltzer SJ. Risk Factors for Progression of Barrett's Esophagus to High Grade Dysplasia and Esophageal Adenocarcinoma. Scientific Reports. 10: 4899. PMID 32184470 DOI: 10.1038/S41598-020-61874-7  0.291
2020 Meltzer SJ. Molecular epigenomic subtypes of Barrett neoplasia. Nature Reviews. Gastroenterology & Hepatology. PMID 32214233 DOI: 10.1038/S41575-020-0292-X  0.29
2011 Song JH, Cheng Y, Yang J, Wu W, Mori Y, Olaru AV, Bootwalla M, Sharpf R, Meltzer SJ. Abstract 4960: Circulating miRNAs as noninvasive biomarkers in esophageal adenocarcinoma patients Cancer Research. 71: 4960-4960. DOI: 10.1158/1538-7445.Am2011-4960  0.29
2019 Kelly RJ, Ansari AM, Miyashita T, Zahurak M, Lay F, Ahmed AK, Born LJ, Pezhouh MK, Salimian KJ, Ng C, Matsangos AE, Stricker-Krongrad AH, Mukaisho KI, Marti GP, Chung CH, ... ... Meltzer SJ, et al. Targeting the Hedgehog Pathway Using Itraconazole to Prevent Progression of Barrett's Esophagus to Invasive Esophageal Adenocarcinoma. Annals of Surgery. PMID 31290765 DOI: 10.1097/Sla.0000000000003455  0.29
2015 Zhang X, Peng Y, Jin Z, Huang W, Cheng Y, Liu Y, Feng X, Yang M, Huang Y, Zhao Z, Wang L, Wei Y, Fan X, Zheng D, Meltzer SJ. Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma. Oncotarget. PMID 26460735 DOI: 10.18632/Oncotarget.5419  0.289
2014 Yellore V, Meltzer SJ, Cheng Y, Stover J. Sa1820 Analytical Validation of a Novel Multi-Gene Assay for Patients With Barrett's Esophagus Gastroenterology. 146: S-303. DOI: 10.1016/S0016-5085(14)61089-1  0.289
2013 Olaru AV, Yamanaka S, Vazquez C, Mori Y, Cheng Y, Abraham JM, Bayless TM, Harpaz N, Selaru FM, Meltzer SJ. MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease. Inflammatory Bowel Diseases. 19: 471-80. PMID 23399735 DOI: 10.1097/Mib.0B013E31827E78Eb  0.288
2009 Jin Z, Cheng Y, Gu W, Zheng Y, Sato F, Mori Y, Olaru AV, Paun BC, Yang J, Kan T, Ito T, Hamilton JP, Selaru FM, Agarwal R, David S, ... ... Meltzer SJ, et al. A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus. Cancer Research. 69: 4112-5. PMID 19435894 DOI: 10.1158/0008-5472.Can-09-0028  0.288
1993 Blount PL, Meltzer SJ, Yin J, Huang Y, Krasna MJ, Reid BJ. Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 90: 3221-5. PMID 8475062 DOI: 10.1073/Pnas.90.8.3221  0.286
1997 Souza RF, Meltzer SJ. The molecular basis for carcinogenesis in metaplastic columnar-lined esophagus. Gastroenterology Clinics of North America. 26: 583-97. PMID 9309406 DOI: 10.1016/S0889-8553(05)70315-0  0.286
2019 Wang Z, Kambhampati S, Cheng Y, Ma K, Simsek C, Tieu AH, Abraham JM, Liu X, Prasath V, Duncan MD, Stark A, Trick A, Tsai HL, Wang H, He Y, ... ... Meltzer SJ, et al. Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett's Esophagus: A Prospective Validation Study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30670490 DOI: 10.1158/1078-0432.Ccr-18-3696  0.285
2001 Meltzer SJ. Tumor genomics vs. tumor genetics: a paradigm shift? Gastroenterology. 121: 726-9. PMID 11522757 DOI: 10.1053/Gast.2001.27808  0.285
2017 Kambhampati S, Luber B, Wang H, Meltzer SJ. Risk Factors for Progression of Barrett's Esophagus to High Grade Dysplasia and Esophageal Adenocarcinoma: A Large Retrospective Cohort Study Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31725-0  0.283
2017 Zhang X, Peng Y, Huang Y, Yang M, Yan R, Zhao Y, Cheng Y, Liu X, Deng S, Feng X, Lin H, Yu H, Chen S, Zhao Z, Li S, ... ... Meltzer SJ, et al. SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling. Cancer Medicine. PMID 29239144 DOI: 10.1002/Cam4.1237  0.282
2009 Selaru FM, Olaru A, Singh V, Kan T, David S, Cheng Y, Mori Y, Yang J, Paun BC, Jin Z, Agarwal R, Hamilton JP, Abraham JM, Torbenson M, Maitra A, ... ... Meltzer SJ, et al. 1073 Micro-RNA 21 Is Overexpressed and Can Accurately Diagnose Human Cholangiocarcinoma Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60746-0  0.282
2009 Olaru A, Cheng Y, Paun BC, Kan T, Selaru FM, Hamilton JP, Jin Z, David S, Agarwal R, Yang J, Abraham JM, Meltzer SJ, Mori Y. S1174 Global DNA Hypomethylation and DNA Methyltransferase-1 Downregulation in Nonneoplastic Colonic Mucosae of Ulcerative Colitis Patients Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60924-0  0.281
2008 Sato F, Jin Z, Schulmann K, Wang J, Greenwald BD, Ito T, Kan T, Hamilton JP, Yang J, Paun B, David S, Olaru A, Cheng Y, Mori Y, Abraham JM, ... ... Meltzer SJ, et al. Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features. Plos One. 3: e1890. PMID 18382671 DOI: 10.1371/Journal.Pone.0001890  0.281
2022 Zhao H, Cheng Y, Kalra A, Ma K, Zheng Y, Ziman B, Tressler C, Glunde K, Shin EJ, Ngamruengphong S, Khashab M, Singh V, Anders RA, Jit S, Wyhs N, ... ... Meltzer SJ, et al. Generation and multiomic profiling of a double-knockout gastroesophageal junction organoid model. Science Translational Medicine. 14: eabq6146. PMID 36449602 DOI: 10.1126/scitranslmed.abq6146  0.28
1993 Rosenblum-Vos LS, Meltzer SJ, Leana-Cox J, Schwartz S. Cytogenetic studies of primary cultures of esophageal squamous cell carcinoma. Cancer Genetics and Cytogenetics. 70: 127-31. PMID 8242593 DOI: 10.1016/0165-4608(93)90182-L  0.279
2020 Deng S, Zhang X, Qin Y, Chen W, Fan H, Feng X, Wang J, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Meltzer SJ, et al. miRNA-192 and -215 activate Wnt/β-catenin signaling pathway in gastric cancer via APC. Journal of Cellular Physiology. PMID 32091625 DOI: 10.1002/Jcp.29550  0.279
2015 Zhang X, Feng X, Peng Y, Yang M, Huang Y, Fan X, Meltzer SJ, Jin Z. Abstract 3996: Integrated analysis of miRNA profiling and bioinformatics reveals the potential key miRNAs in gastric cancer Cancer Research. 75: 3996-3996. DOI: 10.1158/1538-7445.Am2015-3996  0.276
2011 Sato F, Tsuchiya S, Meltzer SJ, Shimizu K. MicroRNAs and epigenetics. The Febs Journal. 278: 1598-609. PMID 21395977 DOI: 10.1111/J.1742-4658.2011.08089.X  0.275
2016 Ch B, Rol e, Lee D, Salem A, Ibrahim S, Mori Y, Meltzer S. Prevalence and Associated Risk Factors of Helicobacter pylori Negative Gastritis Journal of Gastrointestinal and Digestive System. 6. DOI: 10.4172/2161-069X.1000392  0.275
2009 Selaru FM, Olaru AV, Kan T, David S, Cheng Y, Mori Y, Yang J, Paun B, Jin Z, Agarwal R, Hamilton JP, Abraham J, Georgiades C, Alvarez H, Vivekanandan P, ... ... Meltzer SJ, et al. MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology (Baltimore, Md.). 49: 1595-601. PMID 19296468 DOI: 10.1002/Hep.22838  0.275
2017 Ke X, Yan R, Sun Z, Cheng Y, Meltzer A, Lu N, Shu X, Wang Z, Huang B, Liu X, Wang Z, Song JH, Ng CK, Ibrahim S, Abraham JM, ... ... Meltzer SJ, et al. Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids. Neoplasia (New York, N.Y.). 19: 941-949. PMID 28968550 DOI: 10.1016/J.Neo.2017.06.007  0.272
2011 Olaru AV, Selaru FM, Mori Y, Vazquez C, David S, Paun B, Cheng Y, Jin Z, Yang J, Agarwal R, Abraham JM, Dassopoulos T, Harris M, Bayless TM, Kwon J, ... ... Meltzer SJ, et al. Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation. Inflammatory Bowel Diseases. 17: 221-31. PMID 20848542 DOI: 10.1002/Ibd.21359  0.27
2010 Wu F, Zhang S, Dassopoulos T, Harris ML, Bayless TM, Meltzer SJ, Brant SR, Kwon JH. Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflammatory Bowel Diseases. 16: 1729-38. PMID 20848482 DOI: 10.1002/Ibd.21267  0.27
2014 Salem A, Matthews S, Mori Y, Ibrahim S, Meltzer S, Roland BC. Prevalence and Associated Risk Factors of Helicobacter Pylori-Negative Gastritis: 124 The American Journal of Gastroenterology. 109. DOI: 10.14309/00000434-201410002-00124  0.27
2024 Jiang Y, Zhao H, Kong S, Zhou D, Dong J, Cheng Y, Zhang S, Wang F, Kalra A, Yang N, Wei DD, Chen J, Zhang YW, Lin DC, Meltzer SJ, et al. Establishing mouse and human oral esophageal organoids to investigate the tumor immune response. Disease Models & Mechanisms. 17. PMID 38258518 DOI: 10.1242/dmm.050319  0.267
2018 Ansari A, Miyashita T, Lay F, Ahmed AK, Matsangos AE, Born L, Ng C, Cohen RM, Stricker-Krongrad A, Salimian K, Marti GP, Mukaisho K, Pezhouh MK, Marrone K, Meltzer SJ, et al. Targeting the hedgehog pathway in esophageal adenocarcinoma (EAC) using Itraconazole. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E13552  0.266
1998 Balcer-Kubiczek EK, Zhang X, Han L, Harrison GH, Davis CC, Zhou X, Ioffe V, McCready WA, Abraham JM, Meltzer SJ. BIGEL Analysis of Gene Expression in HL60 Cells Exposed to X Rays or 60 Hz Magnetic Fields Radiation Research. 150: 663. DOI: 10.2307/3579889  0.266
2017 Song Y, Kilburn D, Song JH, Cheng Y, Saeui CT, Cheung DG, Croce CM, Yarema KJ, Meltzer SJ, Liu KJ, Wang TH. Determination of absolute expression profiles using multiplexed miRNA analysis. Plos One. 12: e0180988. PMID 28704432 DOI: 10.1371/Journal.Pone.0180988  0.266
2011 Qu D, Sureban SM, May R, Asfa S, Meltzer SJ, Anant S, Houchen CW. Comparative Evaluation of Novel Putative Stem Cell Markers and Tumor Suppressor MicroRNAs in Barrett's Esophagus Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60906-2  0.265
2013 Jin Z, Feng X, Jian Q, Cheng Y, Gao Y, Zhang X, Wang L, Zhang Y, Huang W, Fan X, Chen S, Yu H, Zhao Z, Dong M, Liu J, ... ... Meltzer SJ, et al. Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer. Anticancer Research. 33: 5199-203. PMID 24222170  0.263
2009 Kan T, Sato F, Ito T, Matsumura N, David S, Cheng Y, Agarwal R, Paun BC, Jin Z, Olaru AV, Selaru FM, Hamilton JP, Yang J, Abraham JM, Mori Y, ... Meltzer SJ, et al. The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim. Gastroenterology. 136: 1689-700. PMID 19422085 DOI: 10.1053/J.Gastro.2009.02.002  0.263
2014 Li L, Masica D, Ishida M, Tomuleasa C, Umegaki S, Kalloo AN, Georgiades C, Singh VK, Khashab M, Amateau S, Li Z, Okolo P, Lennon AM, Saxena P, Geschwind JF, ... ... Meltzer SJ, et al. Human bile contains microRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis. Hepatology (Baltimore, Md.). 60: 896-907. PMID 24497320 DOI: 10.1002/Hep.27050  0.262
2008 Arora M, Dutta S, Merchant N, Meltzer S. Evidence for Enhanced Telomerase Activity in Barrettʼs Esophagus with Dysplasia and Adenocarcinoma: 1014 The American Journal of Gastroenterology. 103. DOI: 10.14309/00000434-200809001-01014  0.262
2009 Jin Z, Cheng Y, Gu J, Zheng Y, Mori Y, Olaru A, Paun BC, Kan T, Hamilton JP, Selaru FM, David S, Wolfsen HC, Wallace MB, Shaheen NJ, Washington MK, ... ... Meltzer SJ, et al. 197 A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60168-2  0.258
2017 Hu Q, Sun TT, Hong J, Fang JY, Xiong H, Meltzer SJ. Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis. Plos One. 12: e0169691. PMID 28072858 DOI: 10.1371/Journal.Pone.0169691  0.257
2017 Kroep S, Heberle CR, Curtius K, Kong CY, Lansdorp-Vogelaar I, Ali A, Wolf WA, Shaheen NJ, Spechler SJ, Rubenstein JH, Nishioka NS, Meltzer SJ, Hazelton WD, van Ballegooijen M, Tramontano AC, et al. Impact of Radiofrequency Ablation Treatment of Barrett's Esophagus on Esophageal Adenocarcinoma: A Comparative Modeling Analysis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 28089850 DOI: 10.1016/J.Cgh.2016.12.034  0.257
2007 Kan T, Paun BC, Mori Y, Sato F, Jin Z, Hamilton JP, Ito T, Cheng Y, David S, Olaru AV, Yang J, Agarwal R, Abraham JM, Meltzer SJ. Rarity of Somatic Mutation and Frequency of Normal Sequence Variation Detected in Sporadic Colon Adenocarcinoma Using High-Throughput cDNA Sequencing Bioinformatics and Biology Insights. 1: 117793220700100. DOI: 10.1177/117793220700100001  0.256
2009 Wu F, Zhang S, Mori Y, Bayless TM, Meltzer SJ, Kwon JH. 184 MicroRNAs Are Differentially Expressed in Crohn's Disease Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60155-4  0.255
2020 Yamaguchi K, Soares AO, Goff LA, Talasila A, Choi JA, Ivenitsky D, Karma S, Brophy B, Devine SE, Meltzer SJ, Kazazian HH. Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 33277430 DOI: 10.1073/pnas.2019450117  0.255
2004 Schulmann K, Yin J, Sterian A, Xu T, Sato F, Bryant L, Mori Y, Olaru A, Deacu E, Wang S, Brenner DE, Krasna MJ, Abraham JM, Baron JA, Greenwald BD, ... Meltzer SJ, et al. Methylation profiling for the prediction of Barrett’s esophagus progression Gastroenterology. 127: 331. DOI: 10.1053/J.Gastro.2004.05.007  0.255
2012 Bennett C, Vakil N, Bergman J, Harrison R, Odze R, Vieth M, Sanders S, Gay L, Pech O, Longcroft-Wheaton G, Romero Y, Inadomi J, Tack J, Corley DA, Manner H, ... ... Meltzer SJ, et al. Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process. Gastroenterology. 143: 336-46. PMID 22537613 DOI: 10.1053/J.Gastro.2012.04.032  0.253
2019 Wang Z, Ma K, Cheng Y, Abraham JM, Liu X, Ke X, Wang Z, Meltzer SJ. Synthetic circular multi-miR sponge simultaneously inhibits miR-21 and miR-93 in esophageal carcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31217510 DOI: 10.1038/S41374-019-0273-2  0.253
2022 Luo X, Chang S, Xiao S, Peng Y, Gao Y, Hu F, Liang J, Xu Y, Du K, Chen Y, Qin J, Meltzer SJ, Deng S, Feng X, Fan X, et al. PAD4-dependent citrullination of nuclear translocation of GSK3β promotes colorectal cancer progression via the degradation of nuclear CDKN1A. Neoplasia (New York, N.Y.). 33: 100835. PMID 36113195 DOI: 10.1016/j.neo.2022.100835  0.252
2002 Xu Y, Selaru FM, Yin J, Zou TT, Shustova V, Mori Y, Sato F, Liu TC, Olaru A, Wang S, Kimos MC, Perry K, Desai K, Greenwald BD, Krasna MJ, ... ... Meltzer SJ, et al. Artificial neural networks and gene filtering distinguish between global gene expression profiles of Barrett's esophagus and esophageal cancer. Cancer Research. 62: 3493-7. PMID 12067993  0.251
2008 Selaru FM, Olaru A, Kang K, Jin Z, Maitra A, Torbenson MS, Yang J, Cheng Y, Mori Y, Hamilton JP, Paun BC, Ito T, David S, Agarwal R, Abraham JM, ... ... Meltzer SJ, et al. 431 A Novel MicroRNA Panel Accurately Diagnoses Cholangiocarcinoma Using Nearest Shrunken Centroids Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60293-0  0.25
2021 Li LY, Yang Q, Jiang YY, Yang W, Jiang Y, Li X, Hazawa M, Zhou B, Huang GW, Xu XE, Gery S, Zhang Y, Ding LW, Ho AS, Zumsteg ZS, ... ... Meltzer SJ, et al. Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer. Nature Communications. 12: 4362. PMID 34272396 DOI: 10.1038/s41467-021-24656-x  0.247
2002 Shustova VI, Meltzer SJ. Amplified RNA for gene array hybridizations. Methods in Molecular Biology (Clifton, N.J.). 193: 227-36. PMID 12325513 DOI: 10.1385/1-59259-283-X:227  0.246
2008 Sampliner RE, Wang KK, Shaheen NJ, Wolfsen HC, Wang JS, Meltzer SJ, Washington K, Gu J, Zheng Y. M1995 InterSPORE/EDRN Barrett's Esophagus (BE) Study: Interim Report of a Multicenter Case-Control Study of Progressors to High-Grade Dysplasia/Adenocarcinoma vs. Nonprogressors Gastroenterology. 134: A-447. DOI: 10.1016/S0016-5085(08)62088-0  0.244
2008 Olaru A, Selaru FM, Mori Y, Kang K, Jin Z, David S, Paun BC, Ito T, Cheng Y, Agarwal R, Yang J, Hamilton JP, Abraham JM, Meltzer SJ. S1204 Prediction Analysis of Microarrays to Develop An Accurate MicroRNA Panel for the Diagnosis of IBD-Neoplasia Gastroenterology. 134: A-200-A-201. DOI: 10.1016/S0016-5085(08)60926-9  0.243
2018 Miyoshi J, Gao F, Toden S, Shrubsole MJ, Scarpa M, Whitsett T, Inge L, Meltzer SJ, Teodoro B, Coleman HG, Anderson LA, Wang X, Goel A. 371 - A Novel Non-Invasive Circulating Mirna Signature for Detection of Esophageal Adenocarcinoma Gastroenterology. 154: S-87. DOI: 10.1016/S0016-5085(18)30739-X  0.242
2001 Toretsky JA, Zitomersky NL, Eskenazi AE, Voigt RW, Strauch ED, Sun CC, Huber R, Meltzer SJ, Schlessinger D. Glypican-3 expression in Wilms tumor and hepatoblastoma. Journal of Pediatric Hematology/Oncology. 23: 496-9. PMID 11878776 DOI: 10.1097/00043426-200111000-00006  0.241
2022 Ma K, Kalra A, Tsai HL, Okello S, Cheng Y, Meltzer SJ. Accurate Non-Endoscopic Detection of Esophageal Squamous Cell Carcinoma (ESCC) Using Methylated DNA Biomarkers. Gastroenterology. PMID 35483446 DOI: 10.1053/j.gastro.2022.04.021  0.238
2008 David S, Ito T, Mori Y, Olaru A, Paun BC, Selaru FM, Kang K, Cheng Y, Hamilton JP, Yang J, Agarwal R, Sato F, Abraham JM, Meltzer SJ. M1593 Setting the Stage for Inflammatory Actors: Acid-Induced NF-κB Signaling Decreases the Apoptotic Effects of TNFα in Esophageal Adenocarcinoma Cells Gastroenterology. 134: A-378. DOI: 10.1016/S0016-5085(08)61763-1  0.237
1988 Meltzer SJ, Korelitz BI. Pancreatitis and duodenopancreatic reflux in Crohn's disease. Case report and review of the literature. Journal of Clinical Gastroenterology. 10: 555-8. PMID 3053877 DOI: 10.1097/00004836-198810000-00016  0.233
2012 Agarwal R, Jin Z, Yang J, Mori Y, Song JH, Kumar S, Sato M, Cheng Y, Olaru AV, Abraham JM, Verma A, Meltzer SJ. Epigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways. Endocrine-Related Cancer. 19: L5-9. PMID 22194443 DOI: 10.1530/Erc-11-0364  0.233
2002 Sato F, Harpaz N, Shibata D, Xu Y, Yin J, Mori Y, Zou TT, Wang S, Desai K, Leytin A, Selaru FM, Abraham JM, Meltzer SJ. Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis. Cancer Research. 62: 1148-51. PMID 11861396  0.232
2014 Li L, Masica D, Ishida M, Kalloo AN, Singh VK, Khashab M, Li Z, Okolo P, Lennon AM, Saxena P, Canto MI, Law JK, Goggins MG, Shin EJ, Kumbhari V, ... ... Meltzer SJ, et al. 850d Human bile contains microRNA-laden exosomes that can be used for cholangiocarcinoma diagnosis Gastroenterology. 146: S-145. DOI: 10.1016/S0016-5085(14)60515-1  0.23
2015 Stover J, Meltzer SJ, Haydek JM, Cattau EL, Reiss G. Sa1082 Comparison of Traditional Histology and Histology With Molecular Diagnostic Testing for Risk Stratification of Barrett's Esophagus: A Multi-Center Study Gastroenterology. 148: S-218. DOI: 10.1016/S0016-5085(15)30722-8  0.23
1991 Resau JH, Sakamoto K, Cottrell JR, Hudson EA, Meltzer SJ. Explant organ culture: a review. Cytotechnology. 7: 137-49. PMID 1368116 DOI: 10.1007/Bf00365924  0.226
1998 Cawley HM, Meltzer SJ, De Benedetti VM, Hollstein MC, Muehlbauer KR, Liang L, Bennett WP, Souza RF, Greenwald BD, Cottrell J, Salabes A, Bartsch H, Trivers GE. Anti-p53 antibodies in patients with Barrett's esophagus or esophageal carcinoma can predate cancer diagnosis. Gastroenterology. 115: 19-27. PMID 9649454 DOI: 10.1016/S0016-5085(98)70360-9  0.225
2007 Liu Z, Jiang F, Tian G, Wang S, Sato F, Meltzer SJ, Tan M. Sparse logistic regression with Lp penalty for biomarker identification. Statistical Applications in Genetics and Molecular Biology. 6: Article6. PMID 17402921 DOI: 10.2202/1544-6115.1248  0.224
2015 Bennett C, Moayyedi P, Corley DA, DeCaestecker J, Falck-Ytter Y, Falk G, Vakil N, Sanders S, Vieth M, Inadomi J, Aldulaimi D, Ho KY, Odze R, Meltzer SJ, Quigley E, et al. BOB CAT: a Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia. The American Journal of Gastroenterology. 110: 662-82; quiz 683. PMID 25869390 DOI: 10.1038/Ajg.2015.55  0.224
1989 Present DH, Meltzer SJ, Krumholz MP, Wolke A, Korelitz BI. 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity. Annals of Internal Medicine. 111: 641-9. PMID 2802419 DOI: 10.7326/0003-4819-111-8-641  0.221
2008 Kang K, Sato F, Ito T, David S, Cheng Y, Mori Y, Agarwal R, Paun BC, Jin Z, Olaru A, Selaru F, Hamilton JP, Yang J, Abraham JM, Meltzer SJ. M1600 Upregulation of the Mir-25-93-106b Cluster in Barrett's-Associated Neoplastic Progression Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)61770-9  0.22
1995 Meltzer SJ. Dr. Strange DNA, or how I learned to stop cloning and love the computer. Gastroenterology. 109: 611-4. PMID 7615212 DOI: 10.1016/0016-5085(95)90352-6  0.219
2003 Selaru FM, Mori Y, Sato F, Yin J, Xu Y, Wang S, Olaru A, Deacu E, Liu TC, Abraham JM, Shibata D, Meltzer SJ. Principal components analysis exposes a genomic basis for microsatellite instability status Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80639-X  0.219
2021 Tan X, Ren S, Fu MZ, Ren S, Yang C, Wu X, Chen T, Latham PS, Meltzer SJ, Fu SW. microRNA-196b promotes esophageal squamous cell carcinogenesis and chemoradioresistance by inhibiting EPHA7, thereby restoring EPHA2 activity. American Journal of Cancer Research. 11: 3594-3610. PMID 34354862  0.218
2011 Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, ... ... Meltzer S, et al. Correction: Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis Plos Genetics. 7. DOI: 10.1371/annotation/8dcded85-a924-40f4-a7ea-56961b87447f  0.214
2001 Selaru FM, Xu Y, Yin J, Shustova V, Zou T, Twigg C, Abraham JM, Mori Y, Sato F, Cotaria I, Greenwald BD, Meltzer SJ. Microarray and bioinformatics analyses discriminate among biologic subtypes of esophageal neoplasia Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82206-8  0.214
2002 Whitehall VL, Wynter CV, Walsh MD, Simms LA, Purdie D, Pandeya N, Young J, Meltzer SJ, Leggett BA, Jass JR. Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer. Cancer Research. 62: 6011-4. PMID 12414620  0.213
2009 Wang KK, Fritcher EB, Halling KC, Nelson MA, Bhattacharyya AK, Zheng Y, Gu J, Shaheen NJ, Canto MI, Wang JS, Wolfsen HC, Lutzke LS, Romero Y, Meltzer SJ, Ding IY, et al. 1035 The Use of FISH in a Multi-Center Blinded Study to Predict Development of Neoplasia in Barrett's Esophagus Gastroenterology. 136: A-157. DOI: 10.1016/S0016-5085(09)60708-3  0.212
2015 Bennett C, Moayyedi P, Corley DA, DeCaestecker J, Falck-Ytter Y, Falk G, Vakil N, Sanders S, Vieth M, Inadomi J, Aldulaimi D, Ho KY, Odze R, Meltzer SJ, Quigley E, et al. Addendum: BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia. The American Journal of Gastroenterology. 110: 943. PMID 26052782 DOI: 10.1038/Ajg.2015.151  0.207
2021 Peng Y, Xu Y, Zhang X, Deng S, Yuan Y, Luo X, Hossain MT, Zhu X, Du K, Hu F, Chen Y, Chang S, Feng X, Fan X, Ashktorab H, ... ... Meltzer SJ, et al. A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression. Molecular Cancer. 20: 158. PMID 34863211 DOI: 10.1186/s12943-021-01457-w  0.203
2019 Tsuge S, Saberi B, Cheng Y, Wang Z, Kim A, Luu H, Abraham JM, Ybanez MD, Hamilton JP, Selaru FM, Villacorta-Martin C, Schlesinger F, Philosophe B, Cameron AM, Zhu Q, ... ... Meltzer SJ, et al. Detection of Novel Fusion Transcript VTI1A-CFAP46 in Hepatocellular Carcinoma. Gastrointestinal Tumors. 6: 11-27. PMID 31602373 DOI: 10.1159/000496795  0.202
2017 Eluri S, Parian AM, Limketkai BN, Ha CY, Brant SR, Dudley-Brown S, Efron JE, Fang SG, Gearhart SL, Marohn MR, Meltzer SJ, Bashar S, Truta B, Montgomery EA, Lazarev MG. Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease. Digestive Diseases and Sciences. PMID 28631086 DOI: 10.1007/S10620-017-4652-5  0.198
2014 Stover J, Yellore V, Meltzer S, Cheng Y. Clinical Impact of a Genetic Test in the Treatment and Surveillance of Barrett’s Esophagus: A National Community-Based Study of Gastroenterologists: 91 The American Journal of Gastroenterology. 109. DOI: 10.14309/00000434-201410002-00091  0.194
2002 Jass JR, Whitehall VL, Young J, Leggett B, Meltzer SJ, Matsubara N, Fishel R. Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002. Cancer Research. 62: 5988-9; author reply. PMID 12384567  0.194
2021 Song JH, Tieu AH, Cheng Y, Ma K, Akshintala VS, Simsek C, Prasath V, Shin EJ, Ngamruengphong S, Khashab MA, Abraham JM, Meltzer SJ. Novel Long Noncoding RNA miR205HG Functions as an Esophageal Tumor-Suppressive Hedgehog Inhibitor. Cancers. 13. PMID 33916875 DOI: 10.3390/cancers13071707  0.191
2003 Mori Y, Selaru FM, Sato F, Yin J, Simms LA, Xu Y, Olaru A, Deacu E, Wang S, Taylor JM, Young J, Leggett B, Jass JR, Abraham JM, Shibata D, ... Meltzer SJ, et al. The impact of microsatellite instability on the molecular phenotype of colorectal tumors. Cancer Research. 63: 4577-82. PMID 12907634  0.187
2009 Mori Y, Meltzer SJ. Honey, I shrunk the telomere: UC speeds aging. Inflammatory Bowel Diseases. 15: 1432-3. PMID 19226514 DOI: 10.1002/Ibd.20887  0.183
2016 Meltzer SJ. Leaky transporters and sphincters in Barrett's oesophagus? The Lancet. Oncology. PMID 27527255 DOI: 10.1016/S1470-2045(16)30365-5  0.183
2004 Kan T, Shimada Y, Sato F, Ito T, Kondo K, Watanabe G, Maeda M, Yamasaki S, Meltzer SJ, Imamura M. Prediction of lymph node metastasis with use of artificial neural networks based on gene expression profiles in esophageal squamous cell carcinoma. Annals of Surgical Oncology. 11: 1070-8. PMID 15545505 DOI: 10.1245/ASO.2004.03.007  0.178
2020 Zhang X, Peng Y, Yuan Y, Gao Y, Hu F, Wang J, Zhu X, Feng X, Cheng Y, Wei Y, Fan X, Xie Y, Lv Y, Ashktorab H, Smoot D, ... ... Meltzer SJ, et al. Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells. Cell Death & Disease. 11: 937. PMID 33127874 DOI: 10.1038/s41419-020-03130-4  0.177
2007 Karpathiou G, Argiana E, Koutsopoulos A, Froudarakis ME, Park JY, Kim YS, Bang S, Hyung WJ, Noh SH, Choi SH, Song SY, Wang P, Yang X, Wu P, Zhang J, ... ... Meltzer SJ, et al. Subject Index Vol. 73, 2007 Oncology. 73: 445-446. DOI: 10.1159/000140674  0.173
2007 Karpathiou G, Argiana E, Koutsopoulos A, Froudarakis ME, Park JY, Kim YS, Bang S, Hyung WJ, Noh SH, Choi SH, Song SY, Wang P, Yang X, Wu P, Zhang J, ... ... Meltzer SJ, et al. Contents Vol. 73, 2007 Oncology. 73. DOI: 10.1159/000140682  0.171
2021 Li L, Halpert G, Lerner MG, Hu H, Dimitrion P, Weiss MJ, He J, Philosophe B, Burkhart R, Burns WR, Wesson RN, Cameron AM, Wolfgang CL, Georgiades C, Kawamoto S, ... ... Meltzer SJ, et al. Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma. Jci Insight. PMID 34003798 DOI: 10.1172/jci.insight.138197  0.164
2021 Peng Y, Zhang X, Lin H, Deng S, Qin Y, He J, Hu F, Zhu X, Feng X, Wang J, Wei Y, Fan X, Lin H, Ashktorab H, Smoot D, ... ... Meltzer SJ, et al. Dual activation of Hedgehog and Wnt/β-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer. Aging. 13. PMID 33848981 DOI: 10.18632/aging.202895  0.162
1989 Meltzer SJ, Zhou D, Weinstein WM. Tissue-specific expression of c-Ha-ras in premalignant gastrointestinal mucosae. Experimental and Molecular Pathology. 51: 264-74. PMID 2557232 DOI: 10.1016/0014-4800(89)90024-5  0.158
2000 Dutta SK, Choi YI, Lagerholm S, Fleisher A, Nair PP, Meltzer S. Evidence for enhanced expression of telomerase activity in patients with Barrett's esophagus with dysplasia and adenocarcinoma Gastroenterology. 118: A707. DOI: 10.1016/S0016-5085(00)84959-8  0.157
2005 Sato F, Shimada Y, Selaru FM, Shibata D, Maeda M, Watanabe G, Mori Y, Stass SA, Imamura M, Meltzer SJ. Prediction of survival in patients with esophageal carcinoma using artificial neural networks. Cancer. 103: 1596-605. PMID 15751017 DOI: 10.1002/cncr.20938  0.156
2020 Peng Y, Zhang X, Lin H, Deng S, Qin Y, Yuan Y, Feng X, Wang J, Chen W, Hu F, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, ... ... Meltzer SJ, et al. SUFU mediates EMT and Wnt/β-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. Cell Cycle (Georgetown, Tex.). 1-14. PMID 33017570 DOI: 10.1080/15384101.2020.1826632  0.147
2022 Gong D, Lunz D, Stover JS, Meltzer SJ. The utility of a genetic progression risk test for Barrett esophagus. Medicine. 101: e30503. PMID 36123898 DOI: 10.1097/MD.0000000000030503  0.131
2005 Baquet CR, Commiskey P, Mack K, Meltzer S, Mishra SI. Esophageal cancer epidemiology in blacks and whites: racial and gender disparities in incidence, mortality, survival rates and histology. Journal of the National Medical Association. 97: 1471-8. PMID 16334494  0.13
2021 Peng Y, Qin Y, Zhang X, Deng S, Yuan Y, Feng X, Chen W, Hu F, Gao Y, He J, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, ... ... Meltzer SJ, et al. MiRNA-20b/SUFU/Wnt axis accelerates gastric cancer cell proliferation, migration and EMT. Heliyon. 7: e06695. PMID 33912703 DOI: 10.1016/j.heliyon.2021.e06695  0.126
2020 Chang KH, Shoureshi P, Lay F, Sebastian R, Alikhassy Habibabady Z, Born LJ, Marti GP, Meltzer SJ, Abraham JM, Harmon JW. Preconditioning of surgical pedicle flaps with DNA plasmid expressing hypoxia-inducible factor-1α (HIF-1α) promotes tissue viability. Gene Therapy. PMID 33024315 DOI: 10.1038/s41434-020-00199-6  0.12
2010 Olaru A, Selaru FM, Vazquez C, David S, Mori Y, Luvsanjav D, Cheng Y, Jin Z, Agarwal R, Abraham JM, Harpaz N, Bayless TM, Kwon JH, Meltzer SJ. 253 Dynamic Changes in the Expression of MicroRNA-31 During Inflammatory Bowel Disease Associated Neoplastic Transformation Gastroenterology. 138: S-46. DOI: 10.1016/s0016-5085(10)60211-9  0.104
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