| Year |
Citation |
Score |
| 2023 |
Akbar I, Tang R, Baillargeon J, Roy AP, Doss PMIA, Zhu C, Kuchroo VK, Rangachari M. Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 37909848 DOI: 10.4049/jimmunol.2300526 |
0.456 |
|
| 2023 |
Schnell A, Huang L, Regan BML, Singh V, Vonficht D, Bollhagen A, Wang M, Hou Y, Bod L, Sobel RA, Chihara N, Madi A, Anderson AC, Regev A, Kuchroo VK. Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation. Nature Immunology. 24: 1908-1920. PMID 37828379 DOI: 10.1038/s41590-023-01645-4 |
0.475 |
|
| 2023 |
Ding Q, Wu Y, Triglia ET, Gommerman JL, Subramanian A, Kuchroo VK, Rothstein DM. TIM-4 Identifies Effector B Cells Expressing An IL-23-Driven Proinflammatory Cytokine Module That Promotes Immune Responses. Biorxiv : the Preprint Server For Biology. PMID 37790513 DOI: 10.1101/2023.09.22.558524 |
0.327 |
|
| 2023 |
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, ... ... Kuchroo VK, et al. Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature. PMID 37558878 DOI: 10.1038/s41586-023-06409-6 |
0.338 |
|
| 2023 |
Bod L, Kye YC, Shi J, Torlai Triglia E, Schnell A, Fessler J, Ostrowski SM, Von-Franque MY, Kuchroo JR, Barilla RM, Zaghouani S, Christian E, Delorey TM, Mohib K, Xiao S, ... ... Kuchroo VK, et al. B-cell-specific checkpoint molecules that regulate anti-tumour immunity. Nature. PMID 37344597 DOI: 10.1038/s41586-023-06231-0 |
0.394 |
|
| 2023 |
Cadinu P, Sivanathan KN, Misra A, Xu RJ, Mangani D, Yang E, Rone JM, Tooley K, Kye YC, Bod L, Geistlinger L, Lee T, Ono N, Wang G, Sanmarco L, ... ... Kuchroo VK, et al. Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling. Biorxiv : the Preprint Server For Biology. PMID 37214800 DOI: 10.1101/2023.05.08.539701 |
0.301 |
|
| 2023 |
Sanmarco LM, Rone JM, Polonio CM, Giovannoni F, Lahore GF, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Akl CF, Nanda P, Heck ES, Li Z, Lee HG, ... ... Kuchroo VK, et al. Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Biorxiv : the Preprint Server For Biology. PMID 36993446 DOI: 10.1101/2023.03.17.532101 |
0.369 |
|
| 2023 |
Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, ... ... Kuchroo VK, et al. Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut. Immunity. PMID 36917985 DOI: 10.1016/j.immuni.2023.02.018 |
0.392 |
|
| 2023 |
G Moreira T, Gauthier CD, Murphy L, Lanser TB, Paul A, Matos KTF, Mangani D, Izzy S, Rezende RM, Healy BC, Baecher-Allan CM, Chitnis T, Kuchroo V, Weiner HL. Nasal administration of anti-CD3 mAb (Foralumab) downregulates and increases and expression in T cells in subjects with COVID-19. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220272120. PMID 36881624 DOI: 10.1073/pnas.2220272120 |
0.428 |
|
| 2023 |
Noel S, Lee K, Gharaie S, Kurzhagen JT, Pierorazio PM, Arend LJ, Kuchroo VK, Cahan P, Rabb H. Immune Checkpoint Molecule TIGIT Regulates Kidney T Cell Functions and Contributes to AKI. Journal of the American Society of Nephrology : Jasn. PMID 36747315 DOI: 10.1681/ASN.0000000000000063 |
0.463 |
|
| 2023 |
Schnell A, Littman DR, Kuchroo VK. T17 cell heterogeneity and its role in tissue inflammation. Nature Immunology. 24: 19-29. PMID 36596896 DOI: 10.1038/s41590-022-01387-9 |
0.457 |
|
| 2022 |
Pei W, Kuchroo VK. tRNA-mA modification: a translational checkpoint for T cell expansion. Cell Research. PMID 36550269 DOI: 10.1038/s41422-022-00764-1 |
0.387 |
|
| 2022 |
Pawlak M, DeTomaso D, Schnell A, Meyer Zu Horste G, Lee Y, Nyman J, Dionne D, Regan BML, Singh V, Delorey T, Schramm MA, Wang C, Wallrapp A, Burkett PR, Riesenfeld SJ, ... ... Kuchroo VK, et al. Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Immunity. PMID 36070768 DOI: 10.1016/j.immuni.2022.08.007 |
0.471 |
|
| 2022 |
Spiljar M, Kuchroo VK. Metabolic regulation and function of T helper cells in neuroinflammation. Seminars in Immunopathology. PMID 36068310 DOI: 10.1007/s00281-022-00959-z |
0.464 |
|
| 2022 |
Hernández-Malmierca P, Vonficht D, Schnell A, Uckelmann HJ, Bollhagen A, Mahmoud MAA, Landua SL, van der Salm E, Trautmann CL, Raffel S, Grünschläger F, Lutz R, Ghosh M, Renders S, Correia N, ... ... Kuchroo VK, et al. Antigen presentation safeguards the integrity of the hematopoietic stem cell pool. Cell Stem Cell. 29: 760-775.e10. PMID 35523139 DOI: 10.1016/j.stem.2022.04.007 |
0.344 |
|
| 2022 |
Song Z, Yuan W, Zheng L, Wang X, Kuchroo VK, Mohib K, Rothstein DM. B Cell IL-4 Drives Th2 Responses , Ameliorates Allograft Rejection, and Promotes Allergic Airway Disease. Frontiers in Immunology. 13: 762390. PMID 35359977 DOI: 10.3389/fimmu.2022.762390 |
0.33 |
|
| 2022 |
Pagliano O, Morrison RM, Chauvin JM, Banerjee H, Davar D, Ding Q, Tanegashima T, Gao W, Chakka SR, DeBlasio R, Lowin A, Kara K, Ka M, Zidi B, Amin R, ... ... Kuchroo VK, et al. Tim-3 mediates T cell trogocytosis to limit antitumor immunity. The Journal of Clinical Investigation. PMID 35316223 DOI: 10.1172/JCI152864 |
0.425 |
|
| 2022 |
Sumida TS, Dulberg S, Schupp JC, Lincoln MR, Stillwell HA, Axisa PP, Comi M, Unterman A, Kaminski N, Madi A, Kuchroo VK, Hafler DA. Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells. Nature Immunology. PMID 35301508 DOI: 10.1038/s41590-022-01152-y |
0.372 |
|
| 2022 |
Tang R, Acharya N, Subramanian A, Purohit V, Tabaka M, Hou Y, He D, Dixon KO, Lambden C, Xia J, Rozenblatt-Rosen O, Sobel RA, Wang C, Regev A, Anderson AC, ... Kuchroo VK, et al. Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function. Science Immunology. 7: eabm0631. PMID 35275752 DOI: 10.1126/sciimmunol.abm0631 |
0.799 |
|
| 2022 |
Krovi SH, Kuchroo VK. Activation pathways that drive CD4 T cells to break tolerance in autoimmune diseases. Immunological Reviews. PMID 35142369 DOI: 10.1111/imr.13071 |
0.377 |
|
| 2022 |
Purohit V, Wagner A, Yosef N, Kuchroo VK. Systems-based approaches to study immunometabolism. Cellular & Molecular Immunology. 19: 409-420. PMID 35121805 DOI: 10.1038/s41423-021-00783-9 |
0.724 |
|
| 2021 |
Schnell A, Huang L, Singer M, Singaraju A, Barilla RM, Regan BML, Bollhagen A, Thakore PI, Dionne D, Delorey TM, Pawlak M, Meyer Zu Horste G, Rozenblatt-Rosen O, Irizarry RA, Regev A, ... Kuchroo VK, et al. Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity. Cell. 184: 6281-6298.e23. PMID 34875227 DOI: 10.1016/j.cell.2021.11.018 |
0.421 |
|
| 2021 |
Puleston DJ, Baixauli F, Sanin DE, Edwards-Hicks J, Villa M, Kabat AM, Kamiński MM, Stanckzak M, Weiss HJ, Grzes KM, Piletic K, Field CS, Corrado M, Haessler F, Wang C, ... ... Kuchroo VK, et al. Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell. PMID 34216540 DOI: 10.1016/j.cell.2021.06.007 |
0.511 |
|
| 2021 |
Wagner A, Wang C, Fessler J, DeTomaso D, Avila-Pacheco J, Kaminski J, Zaghouani S, Christian E, Thakore P, Schellhaass B, Akama-Garren E, Pierce K, Singh V, Ron-Harel N, Douglas VP, ... ... Kuchroo VK, et al. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. PMID 34216539 DOI: 10.1016/j.cell.2021.05.045 |
0.44 |
|
| 2021 |
Hafler D, Sumida T, Dulberg S, Schupp J, Stillwell H, Axisa PP, Comi M, Lincoln M, Unterman A, Kaminski N, Madi A, Kuchroo V. Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. Research Square. PMID 34127967 DOI: 10.21203/rs.3.rs-133494/v1 |
0.399 |
|
| 2021 |
Dixon KO, Tabaka M, Schramm MA, Xiao S, Tang R, Dionne D, Anderson AC, Rozenblatt-Rosen O, Regev A, Kuchroo VK. TIM-3 restrains anti-tumour immunity by regulating inflammasome activation. Nature. PMID 34108686 DOI: 10.1038/s41586-021-03626-9 |
0.485 |
|
| 2021 |
Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, ... ... Kuchroo V, et al. Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion. Science Advances. 7. PMID 33931442 DOI: 10.1126/sciadv.abd2710 |
0.524 |
|
| 2021 |
Rudak PT, Choi J, Parkins KM, Summers KL, Jackson DN, Foster PJ, Skaro AI, Leslie K, McAlister VC, Kuchroo VK, Inoue W, Lantz O, Haeryfar SMM. Chronic stress physically spares but functionally impairs innate-like invariant T cells. Cell Reports. 35: 108979. PMID 33852855 DOI: 10.1016/j.celrep.2021.108979 |
0.403 |
|
| 2020 |
Zhang H, Madi A, Yosef N, Chihara N, Awasthi A, Pot C, Lambden C, Srivastava A, Burkett PR, Nyman J, Christian E, Etminan Y, Lee A, Stroh H, Xia J, ... ... Kuchroo VK, et al. An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets. Cell Reports. 33: 108433. PMID 33238123 DOI: 10.1016/j.celrep.2020.108433 |
0.421 |
|
| 2020 |
Hu D, Tjon EC, Andersson KM, Molica GM, Pham MC, Healy B, Murugaiyan G, Pochet N, Kuchroo VK, Bokarewa MI, Weiner HL. Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 33203678 DOI: 10.1073/pnas.2007935117 |
0.361 |
|
| 2020 |
Sungnak W, Wagner A, Kowalczyk MS, Bod L, Kye YC, Sage PT, Sharpe AH, Sobel RA, Quintana FJ, Rozenblatt-Rosen O, Regev A, Wang C, Yosef N, Kuchroo VK. T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 33168576 DOI: 10.4049/jimmunol.2000748 |
0.537 |
|
| 2020 |
Sumida TS, Dulberg S, Schupp J, Stillwell HA, Axisa PP, Comi M, Lincoln M, Unterman A, Kaminski N, Madi A, Kuchroo VK, Hafler DA. Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. Biorxiv : the Preprint Server For Biology. PMID 33140047 DOI: 10.1101/2020.10.30.362947 |
0.409 |
|
| 2020 |
Pawlak M, Ho AW, Kuchroo VK. Cytokines and transcription factors in the differentiation of CD4 T helper cell subsets and induction of tissue inflammation and autoimmunity. Current Opinion in Immunology. 67: 57-67. PMID 33039897 DOI: 10.1016/j.coi.2020.09.001 |
0.511 |
|
| 2020 |
Thangavelu G, Wang C, Loschi M, Saha A, Osborn M, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, ... ... Kuchroo VK, et al. Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses. Blood. PMID 32976550 DOI: 10.1182/blood.2020005628 |
0.514 |
|
| 2020 |
Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, Christian E, Ferreira M, Dixon KO, Fell G, Tooley K, Mangani D, Xia J, Singer M, Bosenberg M, ... ... Kuchroo VK, et al. Endogenous Glucocorticoid Signaling Regulates CD8 T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment. Immunity. 53: 658-671.e6. PMID 32937153 DOI: 10.1016/J.Immuni.2020.08.005 |
0.448 |
|
| 2020 |
Dixon KO, Kuchroo VK. IL-18: throwing off the shackles to boost anti-tumor immunity. Cell Research. PMID 32811976 DOI: 10.1038/S41422-020-00396-3 |
0.331 |
|
| 2020 |
Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, ... Kuchroo VK, et al. Checkpoint Receptor TIGIT Expressed on Tim-1 B Cells Regulates Tissue Inflammation. Cell Reports. 32: 107892. PMID 32668241 DOI: 10.1016/J.Celrep.2020.107892 |
0.448 |
|
| 2020 |
Schnell A, Bod L, Madi A, Kuchroo VK. The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity. Cell Research. PMID 31974523 DOI: 10.1038/S41422-020-0277-X |
0.417 |
|
| 2020 |
Ozmadenci D, Narayanan JSS, Andrew JR, Barrie AM, Jiang S, Bilir E, Bertotto T, White RR, Kuchroo VK, Pachter JA, Stupack DG, Schlaepfer DD. Abstract A26: Modeling the ovarian cancer immune response and tumor microenvironment Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-A26 |
0.432 |
|
| 2019 |
Schorer M, Kuchroo VK, Joller N. Role of Co-stimulatory Molecules in T Helper Cell Differentiation. Advances in Experimental Medicine and Biology. 1189: 153-177. PMID 31758534 DOI: 10.1007/978-981-32-9717-3_6 |
0.585 |
|
| 2019 |
Wang W, Cohen JA, Wallrapp A, Trieu KG, Barrios J, Shao F, Krishnamoorthy N, Kuchroo VK, Jones MR, Fine A, Bai Y, Ai X. Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung. Immunity. PMID 31757673 DOI: 10.1016/J.Immuni.2019.10.002 |
0.39 |
|
| 2019 |
Wolf Y, Anderson AC, Kuchroo VK. TIM3 comes of age as an inhibitory receptor. Nature Reviews. Immunology. PMID 31676858 DOI: 10.1038/S41577-019-0224-6 |
0.468 |
|
| 2019 |
Zhang H, Kuchroo V. Epigenetic and transcriptional mechanisms for the regulation of IL-10. Seminars in Immunology. 44: 101324. PMID 31676122 DOI: 10.1016/J.Smim.2019.101324 |
0.429 |
|
| 2019 |
Delaney C, Schnell A, Cammarata LV, Yao-Smith A, Regev A, Kuchroo VK, Singer M. Combinatorial prediction of marker panels from single-cell transcriptomic data. Molecular Systems Biology. 15: e9005. PMID 31657111 DOI: 10.15252/Msb.20199005 |
0.304 |
|
| 2019 |
Xu H, Ding J, Porter CBM, Wallrapp A, Tabaka M, Ma S, Fu S, Guo X, Riesenfeld SJ, Su C, Dionne D, Nguyen LT, Lefkovith A, Ashenberg O, Burkett PR, ... ... Kuchroo VK, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 51: 696-708.e9. PMID 31618654 DOI: 10.1016/J.Immuni.2019.09.004 |
0.424 |
|
| 2019 |
Wallrapp A, Burkett PR, Riesenfeld SJ, Kim SJ, Christian E, Abdulnour RE, Thakore PI, Schnell A, Lambden C, Herbst RH, Khan P, Tsujikawa K, Xavier RJ, Chiu IM, Levy BD, ... ... Kuchroo VK, et al. Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses. Immunity. PMID 31604686 DOI: 10.1016/J.Immuni.2019.09.005 |
0.399 |
|
| 2019 |
Tang R, Rangachari M, Kuchroo VK. Tim-3: A co-receptor with diverse roles in T cell exhaustion and tolerance. Seminars in Immunology. 42: 101302. PMID 31604535 DOI: 10.1016/J.Smim.2019.101302 |
0.581 |
|
| 2019 |
Clement RL, Daccache J, Mohammed MT, Diallo A, Blazar BR, Kuchroo VK, Lovitch SB, Sharpe AH, Sage PT. Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses. Nature Immunology. PMID 31477921 DOI: 10.1038/S41590-019-0472-4 |
0.557 |
|
| 2019 |
Sungnak W, Wang C, Kuchroo VK. Multilayer regulation of CD4 T cell subset differentiation in the era of single cell genomics. Advances in Immunology. 141: 1-31. PMID 30904130 DOI: 10.1016/Bs.Ai.2018.12.001 |
0.613 |
|
| 2019 |
Kurtulus S, Madi A, Escobar G, Klapholz M, Nyman J, Christian E, Pawlak M, Dionne D, Xia J, Rozenblatt-Rosen O, Kuchroo VK, Regev A, Anderson AC. Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1CD8 Tumor-Infiltrating T Cells. Immunity. 50: 181-194.e6. PMID 30635236 DOI: 10.1016/J.Immuni.2018.11.014 |
0.465 |
|
| 2019 |
Ho A, Xiao S, Madi A, Chihara N, Regev A, Kuchroo V. 087 Molecular and cellular mechanisms of tolerogenic signature induction in CD4+ T cells by apoptotic cells Journal of Investigative Dermatology. 139: S15. DOI: 10.1016/J.Jid.2019.03.163 |
0.514 |
|
| 2018 |
Gandhi AK, Kim WM, Sun ZJ, Huang YH, Bonsor DA, Sundberg EJ, Kondo Y, Wagner G, Kuchroo VK, Petsko G, Blumberg RS. High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3. Scientific Reports. 8: 17512. PMID 30504845 DOI: 10.1038/S41598-018-35754-0 |
0.334 |
|
| 2018 |
Aschenbrenner D, Foglierini M, Jarrossay D, Hu D, Weiner HL, Kuchroo VK, Lanzavecchia A, Notarbartolo S, Sallusto F. Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human T17 cells. Nature Immunology. PMID 30448856 DOI: 10.1038/S41590-018-0264-2 |
0.449 |
|
| 2018 |
Dixon KO, Das M, Kuchroo VK. Human disease mutations highlight the inhibitory function of TIM-3. Nature Genetics. PMID 30405215 DOI: 10.1038/S41588-018-0289-3 |
0.329 |
|
| 2018 |
Biton M, Haber AL, Rogel N, Burgin G, Beyaz S, Schnell A, Ashenberg O, Su CW, Smillie C, Shekhar K, Chen Z, Wu C, Ordovas-Montanes J, Alvarez D, Herbst RH, ... ... Kuchroo V, et al. T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation. Cell. PMID 30392957 DOI: 10.1016/J.Cell.2018.10.008 |
0.523 |
|
| 2018 |
Wallrapp A, Riesenfeld SJ, Burkett PR, Kuchroo VK. Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation. Immunological Reviews. 286: 53-73. PMID 30294962 DOI: 10.1111/Imr.12702 |
0.366 |
|
| 2018 |
Aschenbrenner D, Foglierini M, Jarrossay D, Hu D, Weiner HL, Kuchroo VK, Lanzavecchia A, Notarbartolo S, Sallusto F. An immunoregulatory and tissue-residency program modulated by c-MAF in human T17 cells. Nature Immunology. PMID 30201991 DOI: 10.1038/S41590-018-0200-5 |
0.553 |
|
| 2018 |
Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM. Author Correction: Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Nature Medicine. PMID 30013196 DOI: 10.1038/S41591-018-0093-8 |
0.313 |
|
| 2018 |
Chihara N, Madi A, Kondo T, Zhang H, Acharya N, Singer M, Nyman J, Marjanovic ND, Kowalczyk MS, Wang C, Kurtulus S, Law T, Etminan Y, Nevin J, Buckley CD, ... ... Kuchroo VK, et al. Induction and transcriptional regulation of the co-inhibitory gene module in T cells. Nature. PMID 29899446 DOI: 10.1038/S41586-018-0206-Z |
0.596 |
|
| 2018 |
Biswas A, Shouval DS, Griffith A, Goettel JA, Field M, Kang YH, Konnikova L, Janssen E, Redhu NS, Thrasher AJ, Chatila T, Kuchroo VK, Geha RS, Notarangelo LD, Pai SY, et al. WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nature Communications. 9: 1779. PMID 29725003 DOI: 10.1038/S41467-018-03670-6 |
0.354 |
|
| 2018 |
Meyer Zu Horste G, Przybylski D, Schramm MA, Wang C, Schnell A, Lee Y, Sobel R, Regev A, Kuchroo VK. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 48: 556-569.e7. PMID 29562202 DOI: 10.1016/J.Immuni.2018.03.008 |
0.593 |
|
| 2018 |
Sage PT, Schildberg FA, Sobel RA, Kuchroo VK, Freeman GJ, Sharpe AH. Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 29531164 DOI: 10.4049/Jimmunol.1701231 |
0.358 |
|
| 2018 |
Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM. Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Nature Medicine. PMID 29505031 DOI: 10.1038/Nm.4501 |
0.32 |
|
| 2018 |
Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Sobel RA, Fukumura D, Jain RK, Anderson AC, Kuchroo VK, Joller N. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29500245 DOI: 10.4049/Jimmunol.1700407 |
0.461 |
|
| 2018 |
Wu C, Chen Z, Xiao S, Thalhamer T, Madi A, Han T, Kuchroo V. SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells. Cell Reports. 22: 653-665. PMID 29346764 DOI: 10.1016/J.Celrep.2017.12.068 |
0.565 |
|
| 2018 |
Nakashima H, Alayo QA, Penaloza-MacMaster P, Freeman GJ, Kuchroo VK, Reardon DA, Fernandez S, Caligiuri M, Chiocca EA. Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells. Scientific Reports. 8: 208. PMID 29317703 DOI: 10.1038/S41598-017-18540-2 |
0.464 |
|
| 2018 |
Sabatos-Peyton CA, Nevin J, Brock A, Venable JD, Tan DJ, Kassam N, Xu F, Taraszka J, Wesemann L, Pertel T, Acharya N, Klapholz M, Etminan Y, Jiang X, Huang YH, ... ... Kuchroo VK, et al. Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy. Oncoimmunology. 7: e1385690. PMID 29308307 DOI: 10.1080/2162402X.2017.1385690 |
0.303 |
|
| 2018 |
Razawy W, Salioska N, Asmawidjaja P, Mus A-, Meurs MV, Haspels-Brouwers I, Kops N, Oukka M, Kuchroo V, Lubberts E. THU0032 Ccr6+cd4+ t cells drive antigen-induced arthritis via the il-23r pathway Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2018-Eular.6385 |
0.485 |
|
| 2017 |
Hu D, Notarbartolo S, Croonenborghs T, Patel B, Cialic R, Yang TH, Aschenbrenner D, Andersson KM, Gattorno M, Pham M, Kivisakk P, Pierre IV, Lee Y, Kiani K, Bokarewa M, ... ... Kuchroo VK, et al. Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis. Nature Communications. 8: 1600. PMID 29150604 DOI: 10.1038/S41467-017-01571-8 |
0.512 |
|
| 2017 |
Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JYH, Nevin J, Herbst RH, Yanai I, ... ... Kuchroo VK, et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 171: 1221-1223. PMID 29149608 DOI: 10.1016/j.cell.2017.11.006 |
0.391 |
|
| 2017 |
Brauner S, Jiang X, Thorlacius GE, Lundberg AM, Östberg T, Yan ZQ, Kuchroo VK, Hansson GK, Wahren-Herlenius M. Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content. Cardiovascular Research. PMID 29016728 DOI: 10.1093/Cvr/Cvx181 |
0.316 |
|
| 2017 |
Jacquelot N, Roberti MP, Enot DP, Rusakiewicz S, Ternès N, Jegou S, Woods DM, Sodré AL, Hansen M, Meirow Y, Sade-Feldman M, Burra A, Kwek SS, Flament C, Messaoudene M, ... ... Kuchroo VK, et al. Predictors of responses to immune checkpoint blockade in advanced melanoma. Nature Communications. 8: 592. PMID 28928380 DOI: 10.1038/S41467-017-00608-2 |
0.4 |
|
| 2017 |
Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, ... ... Kuchroo VK, et al. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. PMID 28902842 DOI: 10.1038/Nature24029 |
0.405 |
|
| 2017 |
Joller N, Kuchroo VK. Tim-3, Lag-3, and TIGIT. Current Topics in Microbiology and Immunology. PMID 28900677 DOI: 10.1007/82_2017_62 |
0.538 |
|
| 2017 |
Nylander AN, Ponath GD, Axisa PP, Mubarak M, Tomayko M, Kuchroo VK, Pitt D, Hafler DA. Podoplanin is a negative regulator of Th17 inflammation. Jci Insight. 2. PMID 28878118 DOI: 10.1172/Jci.Insight.92321 |
0.56 |
|
| 2017 |
Ding Q, Mohib K, Kuchroo VK, Rothstein DM. TIM-4 Identifies IFN-γ-Expressing Proinflammatory B Effector 1 Cells That Promote Tumor and Allograft Rejection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28848066 DOI: 10.4049/Jimmunol.1602107 |
0.486 |
|
| 2017 |
Gabriely G, da Cunha AP, Rezende RM, Kenyon B, Madi A, Vandeventer T, Skillin N, Rubino S, Garo L, Mazzola MA, Kolypetri P, Lanser AJ, Moreira T, Faria AMC, Lassmann H, ... Kuchroo V, et al. Targeting latency-associated peptide promotes antitumor immunity. Science Immunology. 2. PMID 28763794 DOI: 10.1126/Sciimmunol.Aaj1738 |
0.483 |
|
| 2017 |
Das M, Zhu C, Kuchroo VK. Tim-3 and its role in regulating anti-tumor immunity. Immunological Reviews. 276: 97-111. PMID 28258697 DOI: 10.1111/Imr.12520 |
0.385 |
|
| 2017 |
Karwacz K, Miraldi ER, Pokrovskii M, Madi A, Yosef N, Wortman I, Chen X, Watters A, Carriero N, Awasthi A, Regev A, Bonneau R, Littman D, Kuchroo VK. Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nature Immunology. PMID 28166218 DOI: 10.1038/Ni.3683 |
0.473 |
|
| 2017 |
Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, Han T, Oukka M, Kuchroo V. The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program. Nature Immunology. PMID 28114290 DOI: 10.1038/Ni.3667 |
0.539 |
|
| 2017 |
Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JY, Nevin J, Herbst RH, Yanai I, ... ... Kuchroo VK, et al. Abstract A10: A distinct gene module for T cell dysfunction uncoupled from T cell activation and controlled by metallothioneins Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A10 |
0.549 |
|
| 2017 |
Razawy W, Asmawidjaja PS, Mus AM, Schreuders-Koedam M, Molendijk M, Oukka M, Kuchroo VK, Eerden BCvd, Lubberts E. 08.14 IL-23 receptor signalling is critical in normal bone remodelling and influences osteoclast activity in vitro and t cell-driven inflammatory bone damage in vivo Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2016-211055.14 |
0.365 |
|
| 2017 |
Chihara N, Madi A, Anderson A, Regev A, Kuchroo V. A gene module driving co-inhibitory receptors expression on T cells Journal of the Neurological Sciences. 381: 531-532. DOI: 10.1016/J.Jns.2017.08.3708 |
0.445 |
|
| 2016 |
Suzuki E, Maverakis E, Sarin R, Bouchareychas L, Kuchroo VK, Nestle FO, Adamopoulos IE. T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798153 DOI: 10.4049/Jimmunol.1600383 |
0.383 |
|
| 2016 |
Sage PT, Ron-Harel N, Juneja VR, Sen DR, Maleri S, Sungnak W, Kuchroo VK, Haining WN, Chevrier N, Haigis M, Sharpe AH. Suppression by TFR cells leads to durable and selective inhibition of B cell effector function. Nature Immunology. PMID 27695002 DOI: 10.1038/Ni.3578 |
0.506 |
|
| 2016 |
Kishi Y, Kondo T, Xiao S, Yosef N, Gaublomme J, Wu C, Wang C, Chihara N, Regev A, Joller N, Kuchroo VK. Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. The Journal of Experimental Medicine. PMID 27670590 DOI: 10.1084/Jem.20151118 |
0.61 |
|
| 2016 |
Singer M, Wang C, Cong L, Marjanovic ND, Kowalczyk MS, Zhang H, Nyman J, Sakuishi K, Kurtulus S, Gennert D, Xia J, Kwon JY, Nevin J, Herbst RH, Yanai I, ... ... Kuchroo VK, et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 166: 1500-1511.e9. PMID 27610572 DOI: 10.1016/J.Cell.2016.08.052 |
0.557 |
|
| 2016 |
Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt RW, Tessier PA, Fuhlbrigge R, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. The Journal of Experimental Medicine. PMID 27551155 DOI: 10.1084/Jem.20150376 |
0.386 |
|
| 2016 |
Meyer Zu Horste G, Wu C, Wang C, Cong L, Pawlak M, Lee Y, Elyaman W, Xiao S, Regev A, Kuchroo VK. RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Reports. PMID 27346359 DOI: 10.1016/J.Celrep.2016.05.088 |
0.492 |
|
| 2016 |
Shim H, Wu C, Ramsamooj S, Bosch KN, Chen Z, Emerling BM, Yun J, Liu H, Choo-Wing R, Yang Z, Wulf GM, Kuchroo VK, Cantley LC. Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune system. Proceedings of the National Academy of Sciences of the United States of America. PMID 27313209 DOI: 10.1073/Pnas.1600934113 |
0.474 |
|
| 2016 |
Anderson AC, Joller N, Kuchroo VK. Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation. Immunity. 44: 989-1004. PMID 27192565 DOI: 10.1016/J.Immuni.2016.05.001 |
0.391 |
|
| 2016 |
Chihara N, Madi A, Karwacz K, Awasthi A, Kuchroo VK. Differentiation and Characterization of Tr1 Cells. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. 113: 3.27.1-3.27.10. PMID 27038462 DOI: 10.1002/0471142735.Im0327S113 |
0.609 |
|
| 2016 |
Jayaraman P, Jacques MK, Zhu C, Steblenko KM, Stowell BL, Madi A, Anderson AC, Kuchroo VK, Behar SM. TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection. Plos Pathogens. 12: e1005490. PMID 26967901 DOI: 10.1371/Journal.Ppat.1005490 |
0.487 |
|
| 2016 |
Razawy W, Alves C, Asmawidjaja P, Mus A, Molendijk M, Dankers W, Oukka M, Kuchroo V, Lubberts E. A2.31 Immunisation with type II collagen (CII) alters the IL-23 receptor expression profile compared to naïve conditions Annals of the Rheumatic Diseases. 75: A27.3-A28. DOI: 10.1136/Annrheumdis-2016-209124.66 |
0.446 |
|
| 2016 |
Frei SM, Shouval DS, Biswas A, Goettel JA, Kang YH, Wu C, Kuchroo V, Snapper SB. 194 Interleukin-23 Receptor Signaling on CD4+ T Cells Is Required for Colitis Mediated by Interleukin-10 Receptor-Deficient Innate Immune Cells Gastroenterology. 150: S51. DOI: 10.1016/S0016-5085(16)30295-5 |
0.504 |
|
| 2015 |
Lee Y, Kuchroo V. Defining the functional states of Th17 cells. F1000research. 4: 132. PMID 27006754 DOI: 10.12688/F1000Research.6116.1 |
0.518 |
|
| 2015 |
Patel DD, Kuchroo VK. Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions. Immunity. 43: 1040-51. PMID 26682981 DOI: 10.1016/J.Immuni.2015.12.003 |
0.469 |
|
| 2015 |
Gaublomme JT, Yosef N, Lee Y, Gertner RS, Yang LV, Wu C, Pandolfi PP, Mak T, Satija R, Shalek AK, Kuchroo VK, Park H, Regev A. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. PMID 26607794 DOI: 10.1016/J.Cell.2015.11.009 |
0.459 |
|
| 2015 |
Wang C, Yosef N, Gaublomme J, Wu C, Lee Y, Clish CB, Kaminski J, Xiao S, Zu Horste GM, Pawlak M, Kishi Y, Joller N, Karwacz K, Zhu C, Ordovas-Montanes M, ... ... Kuchroo VK, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. PMID 26607793 DOI: 10.1016/J.Cell.2015.10.068 |
0.548 |
|
| 2015 |
Hernandez AL, Kitz A, Wu C, Lowther DE, Rodriguez DM, Vudattu N, Deng S, Herold KC, Kuchroo VK, Kleinewietfeld M, Hafler DA. Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells. The Journal of Clinical Investigation. 125: 4212-22. PMID 26524592 DOI: 10.1172/Jci81151 |
0.48 |
|
| 2015 |
Shakya A, Goren A, Shalek A, German CN, Snook J, Kuchroo VK, Yosef N, Chan RC, Regev A, Williams MA, Tantin D. Oct1 and OCA-B are selectively required for CD4 memory T cell function. The Journal of Experimental Medicine. PMID 26481684 DOI: 10.1084/Jem.20150363 |
0.423 |
|
| 2015 |
Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, et al. Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 26438525 DOI: 10.4049/Jimmunol.1402654 |
0.372 |
|
| 2015 |
Kurtulus S, Sakuishi K, Ngiow SF, Joller N, Tan DJ, Teng MW, Smyth MJ, Kuchroo VK, Anderson AC. TIGIT predominantly regulates the immune response via regulatory T cells. The Journal of Clinical Investigation. 125: 4053-62. PMID 26413872 DOI: 10.1172/Jci81187 |
0.56 |
|
| 2015 |
Lee Y, Mitsdoerffer M, Xiao S, Gu G, Sobel RA, Kuchroo VK. IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. PMID 26413871 DOI: 10.1172/Jci75933 |
0.445 |
|
| 2015 |
Peters A, Fowler KD, Chalmin F, Merkler D, Kuchroo VK, Pot C. IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling. Journal of Immunology (Baltimore, Md. : 1950). 195: 4144-53. PMID 26408664 DOI: 10.4049/Jimmunol.1302246 |
0.372 |
|
| 2015 |
Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH. Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. The Journal of Experimental Medicine. 212: 1603-21. PMID 26371185 DOI: 10.1084/Jem.20141030 |
0.574 |
|
| 2015 |
Farez MF, Mascanfroni ID, Méndez-Huergo SP, Yeste A, Murugaiyan G, Garo LP, Balbuena Aguirre ME, Patel B, Ysrraelit MC, Zhu C, Kuchroo VK, Rabinovich GA, Quintana FJ, Correale J. Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses. Cell. 162: 1338-52. PMID 26359987 DOI: 10.1016/J.Cell.2015.08.025 |
0.457 |
|
| 2015 |
Wang C, Collins M, Kuchroo VK. Effector T cell differentiation: are master regulators of effector T cells still the masters? Current Opinion in Immunology. 37: 6-10. PMID 26319196 DOI: 10.1016/J.Coi.2015.08.001 |
0.582 |
|
| 2015 |
Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 7657. PMID 26153760 DOI: 10.1038/Ncomms8657 |
0.497 |
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| 2015 |
Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, ... ... Kuchroo VK, et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron. PMID 26119026 DOI: 10.1016/J.Neuron.2015.06.007 |
0.382 |
|
| 2015 |
Andersson KM, Cavallini NF, Hu D, Brisslert M, Cialic R, Valadi H, Erlandsson MC, Silfverswärd S, Pullerits R, Kuchroo VK, Weiner HL, Bokarewa MI. Pathogenic Transdifferentiation of Th17 Cells Contribute to Perpetuation of Rheumatoid Arthritis during Anti-TNF Treatment. Molecular Medicine (Cambridge, Mass.). 21: 436-543. PMID 26062018 DOI: 10.2119/Molmed.2015.00057 |
0.481 |
|
| 2015 |
Dardalhon V, Collins M, Kuchroo VK. Physical attraction of Th9 cells is skin deep. Annals of Translational Medicine. 3: 74. PMID 25992373 DOI: 10.3978/J.Issn.2305-5839.2015.01.28 |
0.566 |
|
| 2015 |
Burkett PR, Meyer zu Horste G, Kuchroo VK. Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity. The Journal of Clinical Investigation. 125: 2211-9. PMID 25961452 DOI: 10.1172/Jci78085 |
0.472 |
|
| 2015 |
Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV. KIM-1-mediated phagocytosis reduces acute injury to the kidney. The Journal of Clinical Investigation. 125: 1620-36. PMID 25751064 DOI: 10.1172/Jci75417 |
0.366 |
|
| 2015 |
Anderson AC, Sullivan JM, Tan DJ, Lee DH, Kuchroo VK. A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation. Journal of Autoimmunity. 59: 38-42. PMID 25725581 DOI: 10.1016/J.Jaut.2015.02.001 |
0.467 |
|
| 2015 |
Wu C, Chen Z, Kuchroo VK. Ezh2 lines up the chromatin in T regulatory cells. Immunity. 42: 201-3. PMID 25692693 DOI: 10.1016/J.Immuni.2015.01.019 |
0.53 |
|
| 2015 |
Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM. TIM-1 signaling is required for maintenance and induction of regulatory B cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 942-53. PMID 25645598 DOI: 10.1111/Ajt.13087 |
0.486 |
|
| 2015 |
Wu C, Chen Z, Kuchroo VK. DUBA-UBR5 axis: other than transactivation. Cell Research. 25: 273-4. PMID 25633593 DOI: 10.1038/Cr.2015.13 |
0.408 |
|
| 2015 |
Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 6072. PMID 25614966 DOI: 10.1038/Ncomms7072 |
0.533 |
|
| 2015 |
Xiao S, Brooks CR, Sobel RA, Kuchroo VK. Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 1602-8. PMID 25582854 DOI: 10.4049/Jimmunol.1402632 |
0.457 |
|
| 2015 |
Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour RE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN, Levy BD. Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 863-7. PMID 25539814 DOI: 10.4049/Jimmunol.1402534 |
0.445 |
|
| 2015 |
Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of Hepatology. 62: 563-72. PMID 25450716 DOI: 10.1016/J.Jhep.2014.10.034 |
0.481 |
|
| 2015 |
Peters A, Burkett PR, Sobel RA, Buckley CD, Watson SP, Bettelli E, Kuchroo VK. Podoplanin negatively regulates CD4+ effector T cell responses. The Journal of Clinical Investigation. 125: 129-40. PMID 25415436 DOI: 10.1172/Jci74685 |
0.599 |
|
| 2015 |
Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, ... ... Kuchroo VK, et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature. 518: 337-43. PMID 25363779 DOI: 10.1038/Nature13835 |
0.474 |
|
| 2015 |
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, ... ... Kuchroo VK, et al. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 517: 386-90. PMID 25363763 DOI: 10.1038/Nature13848 |
0.546 |
|
| 2015 |
Wang C, Collins M, Kuchroo VK. Effector T cell differentiation: Are master regulators of effector T cells still the masters? Current Opinion in Immunology. 37: 6-10. DOI: 10.1016/j.coi.2015.08.001 |
0.453 |
|
| 2014 |
Quiniou C, Domínguez-Punaro M, Cloutier F, Erfani A, Ennaciri J, Sivanesan D, Sanchez M, Chognard G, Hou X, Rivera JC, Beauchamp C, Charron G, Vilquin M, Kuchroo V, Michnick S, et al. Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R1216-30. PMID 25354400 DOI: 10.1152/Ajpregu.00540.2013 |
0.354 |
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| 2014 |
Speck S, Lim J, Shelake S, Matka M, Stoddard J, Farr A, Kuchroo V, Laouar Y. TGF-β signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation. Plos One. 9: e102390. PMID 25072375 DOI: 10.1371/Journal.Pone.0102390 |
0.319 |
|
| 2014 |
Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 60: 2052-64. PMID 25066922 DOI: 10.1002/Hep.27334 |
0.384 |
|
| 2014 |
Wu C, Thalhamer T, Franca RF, Xiao S, Wang C, Hotta C, Zhu C, Hirashima M, Anderson AC, Kuchroo VK. Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells. Immunity. 41: 270-82. PMID 25065622 DOI: 10.1016/J.Immuni.2014.06.011 |
0.551 |
|
| 2014 |
Kuchroo VK, Anderson AC, Petrovas C. Coinhibitory receptors and CD8 T cell exhaustion in chronic infections. Current Opinion in Hiv and Aids. 9: 439-45. PMID 25010894 DOI: 10.1097/Coh.0000000000000088 |
0.418 |
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| 2014 |
Kuchroo VK, Anderson AC, Freeman GJ. Comment on "Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection". Journal of Immunology (Baltimore, Md. : 1950). 193: 467. PMID 24994907 DOI: 10.4049/Jimmunol.1401123 |
0.449 |
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| 2014 |
Thornley TB, Fang Z, Balasubramanian S, Larocca RA, Gong W, Gupta S, Csizmadia E, Degauque N, Kim BS, Koulmanda M, Kuchroo VK, Strom TB. Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory. The Journal of Clinical Investigation. 124: 3443-54. PMID 24983317 DOI: 10.1172/Jci73527 |
0.36 |
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| 2014 |
Kofler DM, Marson A, Dominguez-Villar M, Xiao S, Kuchroo VK, Hafler DA. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. The Journal of Clinical Investigation. 124: 2513-22. PMID 24812667 DOI: 10.1172/Jci72973 |
0.561 |
|
| 2014 |
da Silva IP, Gallois A, Jimenez-Baranda S, Khan S, Anderson AC, Kuchroo VK, Osman I, Bhardwaj N. Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade. Cancer Immunology Research. 2: 410-22. PMID 24795354 DOI: 10.1158/2326-6066.Cir-13-0171 |
0.54 |
|
| 2014 |
Lee Y, Collins M, Kuchroo VK. Unexpected targets and triggers of autoimmunity. Journal of Clinical Immunology. 34: S56-60. PMID 24789684 DOI: 10.1007/S10875-014-0040-5 |
0.497 |
|
| 2014 |
Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V, Sharpe AH, Quintana FJ, Mathis D, Benoist C, Hafler DA, ... Kuchroo VK, et al. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity. 40: 569-81. PMID 24745333 DOI: 10.1016/J.Immuni.2014.02.012 |
0.594 |
|
| 2014 |
Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, ... ... Kuchroo VK, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 40: 477-89. PMID 24745332 DOI: 10.1016/J.Immuni.2014.04.004 |
0.529 |
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| 2014 |
Czuczman MA, Fattouh R, van Rijn JM, Canadien V, Osborne S, Muise AM, Kuchroo VK, Higgins DE, Brumell JH. Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. Nature. 509: 230-4. PMID 24739967 DOI: 10.1038/Nature13168 |
0.399 |
|
| 2014 |
Angiari S, Donnarumma T, Rossi B, Dusi S, Pietronigro E, Zenaro E, DellaBianca V, Toffali L, Piacentino G, Budui S, Rennert P, Xiao S, Laudanna C, Casasnovas JM, Kuchroo VK, et al. TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity Immunity. 40: 542-553. PMID 24703780 DOI: 10.1016/J.Immuni.2014.03.004 |
0.536 |
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| 2014 |
Clarkson BD, Ling C, Shi Y, Harris MG, Rayasam A, Sun D, Salamat MS, Kuchroo V, Lambris JD, Sandor M, Fabry Z. T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice. The Journal of Experimental Medicine. 211: 595-604. PMID 24616379 DOI: 10.1084/Jem.20131377 |
0.407 |
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| 2014 |
Chognard G, Bellemare L, Pelletier AN, Dominguez-Punaro MC, Beauchamp C, Guyon MJ, Charron G, Morin N, Sivanesan D, Kuchroo V, Xavier R, Michnick SW, Chemtob S, Rioux JD, Lesage S. The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation. Plos One. 9: e89092. PMID 24586521 DOI: 10.1371/Journal.Pone.0089092 |
0.403 |
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| 2014 |
Vega-Carrascal I, Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K, Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG. Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung. Journal of Immunology (Baltimore, Md. : 1950). 192: 2418-31. PMID 24477913 DOI: 10.4049/Jimmunol.1300711 |
0.371 |
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| 2014 |
Joller N, Kuchroo VK. Good guys gone bad: exTreg cells promote autoimmune arthritis. Nature Medicine. 20: 15-7. PMID 24398957 DOI: 10.1038/Nm.3439 |
0.559 |
|
| 2014 |
Fourcade J, Sun Z, Pagliano O, Chauvin JM, Sander C, Janjic B, Tarhini AA, Tawbi HA, Kirkwood JM, Moschos S, Wang H, Guillaume P, Luescher IF, Krieg A, Anderson AC, ... Kuchroo VK, et al. PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8⁺ T cells induced by melanoma vaccines. Cancer Research. 74: 1045-55. PMID 24343228 DOI: 10.1158/0008-5472.Can-13-2908 |
0.431 |
|
| 2014 |
Pires da Silva I, Gallois A, Jimenez-Baranda S, Anderson A, Kuchroo V, Osman I, Bhardwaj N. Melanoma progression is associated with NK cell exhaustion Journal For Immunotherapy of Cancer. 2: O6. DOI: 10.1186/2051-1426-2-S3-O6 |
0.479 |
|
| 2014 |
Kurtulus S, Sakuishi K, Zhang H, Joller N, Tan D, Smyth M, Kuchroo V, Anderson A. Mechanisms of TIGIT-driven immune suppression in cancer Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-O13 |
0.458 |
|
| 2014 |
Ding Q, Xiao S, Kuchroo V, Najafian N, Rothstein D, Yeung M. TIM-1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells through Apoptotic Cell Binding or TIM-1 Ligation. Transplantation. 98: 39-40. DOI: 10.1097/00007890-201407151-00131 |
0.401 |
|
| 2014 |
Angiari S, Donnarumma T, Rossi B, Dusi S, Pietronigro E, Zenaro E, Bianca VD, Piacentino G, Rennert P, Xiao S, Casasnovas JM, Kuchroo VK, Constantin G. TIM-1 is a novel trafficking receptor controlling T cell recruitment in the CNS and induction of experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 275: 196. DOI: 10.1016/J.Jneuroim.2014.08.526 |
0.482 |
|
| 2014 |
Horste GMz, Wu C, Lee Y, Elyaman W, Kuchroo VK. Identification of a transcriptional regulator of pathogenicity of Th17 cells Journal of Neuroimmunology. 275: 164. DOI: 10.1016/J.Jneuroim.2014.08.441 |
0.427 |
|
| 2014 |
Mascanfroni I, Yeste A, Vieira S, Burns E, Patel B, Sloma I, Wu Y, Mayo L, Ben-hamo R, Efroni S, Kuchroo V, Robson S, Quintana F. IL-27 acts on DCs to suppress CNS autoimmunity by inducing CD39 expression Journal of Neuroimmunology. 275: 88. DOI: 10.1016/J.Jneuroim.2014.08.236 |
0.394 |
|
| 2013 |
Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S, Kuchroo VK, Robson SC, Quintana FJ. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nature Immunology. 14: 1054-63. PMID 23995234 DOI: 10.1038/Ni.2695 |
0.543 |
|
| 2013 |
Lozano E, Joller N, Cao Y, Kuchroo VK, Hafler DA. The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans. Journal of Immunology (Baltimore, Md. : 1950). 191: 3673-80. PMID 23980210 DOI: 10.4049/Jimmunol.1300945 |
0.492 |
|
| 2013 |
Sjöstrand M, Ambrosi A, Brauner S, Sullivan J, Malin S, Kuchroo VK, Espinosa A, Wahren-Herlenius M. Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors. Journal of Immunology (Baltimore, Md. : 1950). 191: 3753-63. PMID 23975864 DOI: 10.4049/Jimmunol.1202341 |
0.411 |
|
| 2013 |
Rangachari M, Kuchroo VK. Using EAE to better understand principles of immune function and autoimmune pathology. Journal of Autoimmunity. 45: 31-9. PMID 23849779 DOI: 10.1016/J.Jaut.2013.06.008 |
0.562 |
|
| 2013 |
Jianjun Yang, Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, ... ... Kuchroo VK, et al. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. The Journal of Experimental Medicine. 210: 1447-62. PMID 23797094 DOI: 10.1084/Jem.20122494 |
0.562 |
|
| 2013 |
Sakuishi K, Ngiow SF, Sullivan JM, Teng MW, Kuchroo VK, Smyth MJ, Anderson AC. TIM3(+)FOXP3(+) regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer. Oncoimmunology. 2: e23849. PMID 23734331 DOI: 10.4161/Onci.23849 |
0.56 |
|
| 2013 |
Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 7802-7. PMID 23630250 DOI: 10.1073/Pnas.1211776110 |
0.43 |
|
| 2013 |
Mitsdoerffer M, Kuchroo V, Korn T. Immunology of neuromyelitis optica: a T cell-B cell collaboration. Annals of the New York Academy of Sciences. 1283: 57-66. PMID 23617588 DOI: 10.1111/Nyas.12118 |
0.495 |
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| 2013 |
Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF. Regulatory T cells: recommendations to simplify the nomenclature. Nature Immunology. 14: 307-8. PMID 23507634 DOI: 10.1038/Ni.2554 |
0.538 |
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| 2013 |
Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson AC, Kuchroo VK, Remold HG, Behar SM. IL-1β promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation. Journal of Immunology (Baltimore, Md. : 1950). 190: 4196-204. PMID 23487424 DOI: 10.4049/Jimmunol.1202688 |
0.369 |
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| 2013 |
Sutherland AP, Joller N, Michaud M, Liu SM, Kuchroo VK, Grusby MJ. IL-21 promotes CD8+ CTL activity via the transcription factor T-bet. Journal of Immunology (Baltimore, Md. : 1950). 190: 3977-84. PMID 23479229 DOI: 10.4049/Jimmunol.1201730 |
0.522 |
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| 2013 |
Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, ... ... Kuchroo VK, et al. Dynamic regulatory network controlling TH17 cell differentiation. Nature. 496: 461-8. PMID 23467089 DOI: 10.1038/Nature11981 |
0.507 |
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| 2013 |
Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y, Regev A, Kuchroo VK. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature. 496: 513-7. PMID 23467085 DOI: 10.1038/Nature11984 |
0.468 |
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| 2013 |
Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH. MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 2270-5. PMID 23341605 DOI: 10.1073/Pnas.1206048110 |
0.581 |
|
| 2013 |
Ichinose K, Zhang Z, Koga T, Juang YT, Kis-Tóth K, Sharpe AH, Kuchroo V, Crispín JC, Tsokos GC. Brief report: increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice. Arthritis and Rheumatism. 65: 764-9. PMID 23203389 DOI: 10.1002/Art.37790 |
0.478 |
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| 2013 |
Wang C, Wu L, Bulek K, Martin BN, Zepp JA, Kang Z, Liu C, Herjan T, Misra S, Carman JA, Gao J, Dongre A, Han S, Bunting KD, Ko JS, ... ... Kuchroo VK, et al. The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90. Nature Immunology. 14: 72-81. PMID 23202271 DOI: 10.1038/Ni.2479 |
0.394 |
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| 2013 |
Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Erratum: Corrigendum: Aiolos promotes TH17 differentiation by directly silencing Il2 expression Nature Immunology. 15: 109-109. DOI: 10.1038/Ni0114-109B |
0.304 |
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| 2013 |
Wang C, Wu L, Bulek K, Martin BN, Zepp JA, Kang Z, Liu C, Herjan T, Misra S, Carman JA, Gao J, Dongre A, Han S, Bunting KD, Ko JS, ... ... Kuchroo VK, et al. 272 : The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone Hsp90 Cytokine. 63: 307. DOI: 10.1016/J.Cyto.2013.06.275 |
0.383 |
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| 2013 |
Pot C, Quintana FJ, Kuchroo VK. Fine tuning of the immune response by the Aryl Hydrocarbon Receptor Seminars in Immunopathology. 35: 613-613. DOI: 10.1007/S00281-013-0398-0 |
0.366 |
|
| 2012 |
Balasubramanian S, Kota SK, Kuchroo VK, Humphreys BD, Strom TB. TIM family proteins promote the lysosomal degradation of the nuclear receptor NUR77. Science Signaling. 5: ra90. PMID 23233528 DOI: 10.1126/Scisignal.2003200 |
0.457 |
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| 2012 |
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9. PMID 22961052 DOI: 10.1038/Ni.2416 |
0.519 |
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| 2012 |
Kuchroo VK, Awasthi A. Emerging new roles of Th17 cells. European Journal of Immunology. 42: 2211-4. PMID 22949318 DOI: 10.1002/Eji.201242872 |
0.425 |
|
| 2012 |
Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, ... ... Kuchroo V, et al. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity. 37: 276-89. PMID 22884313 DOI: 10.1016/J.Immuni.2012.05.022 |
0.396 |
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| 2012 |
Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, ... Kuchroo VK, et al. Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. Nature Medicine. 18: 1394-400. PMID 22863785 DOI: 10.1038/Nm.2871 |
0.576 |
|
| 2012 |
Vignali DA, Kuchroo VK. IL-12 family cytokines: immunological playmakers. Nature Immunology. 13: 722-8. PMID 22814351 DOI: 10.1038/Ni.2366 |
0.32 |
|
| 2012 |
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 12105-10. PMID 22773818 DOI: 10.1073/Pnas.1120914109 |
0.446 |
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| 2012 |
Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nature Medicine. 18: 1248-53. PMID 22772464 DOI: 10.1038/Nm.2856 |
0.472 |
|
| 2012 |
Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nature Immunology. 13: 770-7. PMID 22751139 DOI: 10.1038/Ni.2363 |
0.508 |
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| 2012 |
Joller N, Peters A, Anderson AC, Kuchroo VK. Immune checkpoints in central nervous system autoimmunity. Immunological Reviews. 248: 122-39. PMID 22725958 DOI: 10.1111/J.1600-065X.2012.01136.X |
0.555 |
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| 2012 |
Gupta S, Thornley TB, Gao W, Larocca R, Turka LA, Kuchroo VK, Strom TB. Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs. The Journal of Clinical Investigation. 122: 2395-404. PMID 22684103 DOI: 10.1172/Jci45138 |
0.503 |
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| 2012 |
Veenstra RG, Taylor PA, Zhou Q, Panoskaltsis-Mortari A, Hirashima M, Flynn R, Liu D, Anderson AC, Strom TB, Kuchroo VK, Blazar BR. Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells. Blood. 120: 682-90. PMID 22677125 DOI: 10.1182/Blood-2011-10-387977 |
0.558 |
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| 2012 |
Fowler KD, Kuchroo VK, Chakraborty AK. A model for how signal duration can determine distinct outcomes of gene transcription programs. Plos One. 7: e33018. PMID 22427931 DOI: 10.1371/Journal.Pone.0033018 |
0.333 |
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| 2012 |
Lozano E, Dominguez-Villar M, Kuchroo V, Hafler DA. The TIGIT/CD226 axis regulates human T cell function. Journal of Immunology (Baltimore, Md. : 1950). 188: 3869-75. PMID 22427644 DOI: 10.4049/Jimmunol.1103627 |
0.573 |
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| 2012 |
Cedeno-Laurent F, Opperman M, Barthel SR, Kuchroo VK, Dimitroff CJ. Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. Journal of Immunology (Baltimore, Md. : 1950). 188: 3127-37. PMID 22345665 DOI: 10.4049/Jimmunol.1103433 |
0.571 |
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| 2012 |
Anderson AC, Chandwaskar R, Lee DH, Sullivan JM, Solomon A, Rodriguez-Manzanet R, Greve B, Sobel RA, Kuchroo VK. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2084-92. PMID 22279107 DOI: 10.4049/Jimmunol.1102186 |
0.82 |
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| 2012 |
Kuchroo VK, Ohashi PS, Sartor RB, Vinuesa CG. Dysregulation of immune homeostasis in autoimmune diseases. Nature Medicine. 18: 42-7. PMID 22227671 DOI: 10.1038/Nm.2621 |
0.403 |
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| 2012 |
Fourcade J, Sun Z, Pagliano O, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Olive D, Kuchroo V, Zarour HM. CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Research. 72: 887-96. PMID 22205715 DOI: 10.1158/0008-5472.Can-11-2637 |
0.523 |
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| 2012 |
Liu SM, Sutherland APR, Zhang Z, Rainbow DB, Quintana FJ, Paterson AM, Sharpe AH, Oukka M, Wicker LS, Kuchroo VK. Overexpression of the CTLA-4 isoform lacking exons 2 and 3 causes autoimmunity Journal of Immunology. 188: 155-162. PMID 22124121 DOI: 10.4049/Jimmunol.1102042 |
0.539 |
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| 2012 |
Pires Da Silva IED, Jimenez-Baranda S, Gallois A, Kuchroo V, Osman I, Bhardwaj N. Tim-3 expression and function in natural killer cells from advanced melanoma patients. Journal of Clinical Oncology. 30: 8571-8571. DOI: 10.1200/Jco.2012.30.15_Suppl.8571 |
0.465 |
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| 2012 |
Silva IPd, Jimenez-Baranda S, Gallois A, Kuchroo VK, Osman I, Bhardwaj N. Abstract 5410: Tim-3 expression and function in natural killer cells from metastatic melanoma patients Cancer Research. 72: 5410-5410. DOI: 10.1158/1538-7445.Am2012-5410 |
0.535 |
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| 2012 |
Fourcade J, Sun Z, Pagliano O, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Olive D, Kuchroo V, Zarour HM. Abstract 5407: The upregulation of BTLA and PD-1 defines a novel subset of dysfunctional tumor antigen-specific CD8+ T cells Cancer Research. 72: 5407-5407. DOI: 10.1158/1538-7445.Am2012-5407 |
0.482 |
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| 2012 |
Maldonado R, Perdomo L, Vascotto F, Francisco L, Bauquet A, Kuchroo V, Sharpe A, von Andrian U. Induced-Tolerogenic Dendritic Cells That Promote Tolerance And De Novo Differentiation Of Regulatory T Cells Journal of Allergy and Clinical Immunology. 129: AB116. DOI: 10.1016/J.Jaci.2011.12.563 |
0.537 |
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| 2011 |
Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity. 35: 986-96. PMID 22177922 DOI: 10.1016/J.Immuni.2011.10.015 |
0.498 |
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| 2011 |
Sharma S, Sundararajan A, Suryawanshi A, Kumar N, Veiga-Parga T, Kuchroo VK, Thomas PG, Sangster MY, Rouse BT. T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 19001-6. PMID 22052881 DOI: 10.1073/Pnas.1107087108 |
0.459 |
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| 2011 |
Liu SM, Lee DH, Sullivan JM, Chung D, Jäger A, Shum BO, Sarvetnick NE, Anderson AC, Kuchroo VK. Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice. The Journal of Clinical Investigation. 121: 4303-10. PMID 22019586 DOI: 10.1172/Jci46187 |
0.425 |
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| 2011 |
Peters A, Lee Y, Kuchroo VK. The many faces of Th17 cells. Current Opinion in Immunology. 23: 702-6. PMID 21899997 DOI: 10.1016/J.Coi.2011.08.007 |
0.507 |
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| 2011 |
Pot C, Apetoh L, Awasthi A, Kuchroo VK. Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27. Seminars in Immunology. 23: 438-45. PMID 21893418 DOI: 10.1016/J.Smim.2011.08.003 |
0.481 |
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| 2011 |
Awasthi A, Kuchroo VK. Value added: neural progenitor cells suppress inflammation and autoimmunity. Immunity. 35: 156-7. PMID 21867924 DOI: 10.1016/J.Immuni.2011.08.005 |
0.425 |
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| 2011 |
Pot C, Apetoh L, Kuchroo VK. Type 1 regulatory T cells (Tr1) in autoimmunity. Seminars in Immunology. 23: 202-8. PMID 21840222 DOI: 10.1016/J.Smim.2011.07.005 |
0.54 |
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| 2011 |
Lee J, Su EW, Zhu C, Hainline S, Phuah J, Moroco JA, Smithgall TE, Kuchroo VK, Kane LP. Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways. Molecular and Cellular Biology. 31: 3963-74. PMID 21807895 DOI: 10.1128/Mcb.05297-11 |
0.517 |
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| 2011 |
Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, et al. Control of TH17 cells occurs in the small intestine. Nature. 475: 514-8. PMID 21765430 DOI: 10.1038/Nature10228 |
0.534 |
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| 2011 |
Thakker P, Marusic S, Stedman NL, Lee KL, McKew JC, Wood A, Goldman SJ, Leach MW, Collins M, Kuchroo VK, Wolf SF, Clark JD, Hassan-Zahraee M. Cytosolic phospholipase A2α blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs. Journal of Immunology (Baltimore, Md. : 1950). 187: 1986-97. PMID 21746963 DOI: 10.4049/Jimmunol.1002789 |
0.364 |
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| 2011 |
Sakuishi K, Jayaraman P, Behar SM, Anderson AC, Kuchroo VK. Emerging Tim-3 functions in antimicrobial and tumor immunity. Trends in Immunology. 32: 345-9. PMID 21697013 DOI: 10.1016/J.It.2011.05.003 |
0.579 |
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| 2011 |
Xiao S, Zhu B, Jin H, Zhu C, Umetsu DT, DeKruyff RH, Kuchroo VK. Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells. European Journal of Immunology. 41: 1539-49. PMID 21469101 DOI: 10.1002/Eji.201040993 |
0.592 |
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| 2011 |
Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy WJ, Azuma M, Anderson AC, Kuchroo VK, Blazar BR. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood. 117: 4501-10. PMID 21385853 DOI: 10.1182/Blood-2010-10-310425 |
0.467 |
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| 2011 |
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Cutting edge: TIGIT has T cell-intrinsic inhibitory functions. Journal of Immunology (Baltimore, Md. : 1950). 186: 1338-42. PMID 21199897 DOI: 10.4049/Jimmunol.1003081 |
0.581 |
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| 2011 |
Lazarevic V, Chen X, Shim JH, Hwang ES, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nature Immunology. 12: 96-104. PMID 21151104 DOI: 10.1038/Ni.1969 |
0.502 |
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| 2011 |
Zhu C, Anderson AC, Kuchroo VK. TIM-3 and its regulatory role in immune responses. Current Topics in Microbiology and Immunology. 350: 1-15. PMID 20700701 DOI: 10.1007/82_2010_84 |
0.6 |
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| 2011 |
Fourcade J, Sun Z, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Kuchroo V, Zarour HM. Abstract 3657: Upregulation of PD-1 and Tim-3 expression on tumor antigen-specific CD4+ T cells is associated with reversible T cell dysfunction in patients with advanced melanoma Cancer Research. 71: 3657-3657. DOI: 10.1158/1538-7445.Am2011-3657 |
0.473 |
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| 2010 |
Jayaraman P, Sada-Ovalle I, Beladi S, Anderson AC, Dardalhon V, Hotta C, Kuchroo VK, Behar SM. Tim3 binding to galectin-9 stimulates antimicrobial immunity. The Journal of Experimental Medicine. 207: 2343-54. PMID 20937702 DOI: 10.1084/Jem.20100687 |
0.531 |
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| 2010 |
Petermann F, Rothhammer V, Claussen MC, Haas JD, Blanco LR, Heink S, Prinz I, Hemmer B, Kuchroo VK, Oukka M, Korn T. γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. Immunity. 33: 351-63. PMID 20832339 DOI: 10.1016/J.Immuni.2010.08.013 |
0.571 |
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| 2010 |
Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, Anderson AC. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. The Journal of Experimental Medicine. 207: 2187-94. PMID 20819927 DOI: 10.1084/Jem.20100643 |
0.414 |
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| 2010 |
Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Kuchroo V, Zarour HM. Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. The Journal of Experimental Medicine. 207: 2175-86. PMID 20819923 DOI: 10.1084/Jem.20100637 |
0.457 |
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| 2010 |
Jäger A, Kuchroo VK. Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation. Scandinavian Journal of Immunology. 72: 173-84. PMID 20696013 DOI: 10.1111/J.1365-3083.2010.02432.X |
0.599 |
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| 2010 |
Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 14733-8. PMID 20679213 DOI: 10.1073/Pnas.1009731107 |
0.517 |
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| 2010 |
Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, Burns EJ, Sherr DH, Weiner HL, Kuchroo VK. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nature Immunology. 11: 854-61. PMID 20676095 DOI: 10.1038/Ni.1912 |
0.489 |
|
| 2010 |
Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK, Cantor H, Bettellie E, Kuchroo VK. Proinflammatory T helper type 17 cells are effective B-cell helpers Proceedings of the National Academy of Sciences of the United States of America. 107: 14292-14297. PMID 20660725 DOI: 10.1073/Pnas.1009234107 |
0.546 |
|
| 2010 |
Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, Cornejo M, Nishi N, Yamauchi A, Quintana FJ, Sobel RA, Hirashima M, Kuchroo VK. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 1383-92. PMID 20574007 DOI: 10.4049/Jimmunol.0903275 |
0.522 |
|
| 2010 |
Pot C, Apetoh L, Awasthi A, Kuchroo VK. Molecular pathways in the induction of interleukin-27-driven regulatory type 1 cells Journal of Interferon &Amp; Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 381-388. PMID 20540648 DOI: 10.1089/Jir.2010.0047 |
0.401 |
|
| 2010 |
Beriou G, Bradshaw EM, Lozano E, Costantino CM, Hastings WD, Orban T, Elyaman W, Khoury SJ, Kuchroo VK, Baecher-Allan C, Hafler DA. TGF-beta induces IL-9 production from human Th17 cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 46-54. PMID 20498357 DOI: 10.4049/Jimmunol.1000356 |
0.404 |
|
| 2010 |
Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 8706-11. PMID 20368430 DOI: 10.1073/Pnas.0910359107 |
0.8 |
|
| 2010 |
Kyttaris VC, Zhang Z, Kuchroo VK, Oukka M, Tsokos GC. Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 4605-9. PMID 20308633 DOI: 10.4049/Jimmunol.0903595 |
0.425 |
|
| 2010 |
Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M. IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. Journal of Immunology (Baltimore, Md. : 1950). 184: 1710-20. PMID 20083652 DOI: 10.4049/Jimmunol.0902796 |
0.463 |
|
| 2010 |
Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. T-bet, a Th1 transcription factor regulates the expression of Tim-3. European Journal of Immunology. 40: 859-66. PMID 20049876 DOI: 10.1002/Eji.200939842 |
0.525 |
|
| 2010 |
Korn T, Mitsdoerffer M, Kuchroo VK. Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis. Results and Problems in Cell Differentiation. 51: 43-74. PMID 19513635 DOI: 10.1007/400_2008_17 |
0.503 |
|
| 2010 |
Franco Salinas G, Cantaert T, Nolte M, Bettelli E, Kuchroo VK, Tak PP, Van Lier RA, Baeten DL. Constitutive co-stimulation by B cells is sufficient to trigger T cell-driven autoimmune disease Annals of the Rheumatic Diseases. 69: A71-A71. DOI: 10.1136/Ard.2010.129668Q |
0.548 |
|
| 2010 |
Saleh MA, Ishii K, Kim Y, Murakami A, Amagai M, Shibaguchi H, Tsuru H, Kuroki M, Murata A, Okuyama K, Sawada A, Egawa Y, Sakano S, Yagita H, Zúñiga-Pflücker JC, ... ... Kuchroo VK, et al. Cell adhesion in immunity (WS-103) Chairpersons: Tatsuo Kinashi, Sirpa Jalkanen International Immunology. 22. DOI: 10.1093/Intimm/Dxq365 |
0.417 |
|
| 2010 |
Sakaguchi S, Shevach E, Rudensky A, Cua D, Kuchroo V, Littman D. Th17 / Treg (SY2-1) Chairpersons: Shimon Sakaguchi, Daniel Cua International Immunology. 22. DOI: 10.1093/Intimm/Dxq145 |
0.391 |
|
| 2010 |
Sakuishi K, Apetoh L, Kuchroo V, Anderson A. Tim-3/Tim-3L Pathway as a Target for Restoring Effector Functions in Exhausted CD8 Lymphocytes in Tumors Clinical Immunology. 135: S12. DOI: 10.1016/J.Clim.2010.03.044 |
0.312 |
|
| 2010 |
Apetoh L, Pot C, Quintana F, Weiner H, Kuchroo V. Transcriptional Regulation of IL-10-producing Regulatory Type 1 Cells Clinical Immunology. 135: S5. DOI: 10.1016/J.Clim.2010.03.022 |
0.387 |
|
| 2009 |
Francisco LM, Salinas VH, Brown KE, Vanguri VK, Freeman GJ, Kuchroo VK, Sharpe AH. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. The Journal of Experimental Medicine. 206: 3015-29. PMID 20008522 DOI: 10.1084/Jem.20090847 |
0.396 |
|
| 2009 |
Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. Journal of Immunology (Baltimore, Md. : 1950). 183: 7169-77. PMID 19890056 DOI: 10.4049/Jimmunol.0901906 |
0.546 |
|
| 2009 |
Araki M, Chung D, Liu S, Rainbow DB, Chamberlain G, Garner V, Hunter KM, Vijayakrishnan L, Peterson LB, Oukka M, Sharpe AH, Sobel R, Kuchroo VK, Wicker LS. Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5146-57. PMID 19783679 DOI: 10.4049/Jimmunol.0802610 |
0.371 |
|
| 2009 |
Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. The New England Journal of Medicine. 361: 888-98. PMID 19710487 DOI: 10.1056/Nejmra0707449 |
0.556 |
|
| 2009 |
Awasthi A, Kuchroo VK. The yin and yang of follicular helper t cells Science. 325: 953-955. PMID 19696339 DOI: 10.1126/Science.1178752 |
0.53 |
|
| 2009 |
Hastings WD, Anderson DE, Kassam N, Koguchi K, Greenfield EA, Kent SC, Zheng XX, Strom TB, Hafler DA, Kuchroo VK. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. European Journal of Immunology. 39: 2492-501. PMID 19676072 DOI: 10.1002/Eji.200939274 |
0.573 |
|
| 2009 |
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana FJ, Sjöstrand M, Eloranta ML, Nà Gabhann J, Winqvist O, Sundelin B, Jefferies CA, Rozell B, Kuchroo VK, Wahren-Herlenius M. Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway. The Journal of Experimental Medicine. 206: 1661-71. PMID 19635858 DOI: 10.1084/Jem.20090585 |
0.368 |
|
| 2009 |
Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, Castelblanco N, Kuchroo V, Gretch DR, Rosen HR. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. Journal of Virology. 83: 9122-30. PMID 19587053 DOI: 10.1128/Jvi.00639-09 |
0.498 |
|
| 2009 |
Pot C, Jin H, Awasthi A, Liu SM, Lai CY, Madan R, Sharpe AH, Karp CL, Miaw SC, Ho IC, Kuchroo VK. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 797-801. PMID 19570826 DOI: 10.4049/Jimmunol.0901233 |
0.365 |
|
| 2009 |
Awasthi A, Kuchroo VK. IL-17A directly inhibits TH1 cells and thereby suppresses development of intestinal inflammation Nature Immunology. 10: 568-570. PMID 19448657 DOI: 10.1038/Ni0609-568 |
0.514 |
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| 2009 |
Elyaman W, Bradshaw EM, Uyttenhove C, Dardalhon V, Awasthi A, Imitola J, Bettelli E, Oukka M, van Snick J, Renauld JC, Kuchroo VK, Khoury SJ. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 12885-90. PMID 19433802 DOI: 10.1016/J.Clim.2009.03.093 |
0.537 |
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| 2009 |
Rodriguez-Manzanet R, DeKruyff R, Kuchroo VK, Umetsu DT. The costimulatory role of TIM molecules. Immunological Reviews. 229: 259-70. PMID 19426227 DOI: 10.1111/J.1600-065X.2009.00772.X |
0.84 |
|
| 2009 |
Awasthi A, Riol-Blanco L, Jäger A, Korn T, Pot C, Galileos G, Bettelli E, Kuchroo VK, Oukka M. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5904-8. PMID 19414740 DOI: 10.4049/Jimmunol.0900732 |
0.373 |
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| 2009 |
Kaufmann SH, Kuchroo VK. Th17 cells. Microbes and Infection. 11: 579-83. PMID 19379826 DOI: 10.1016/j.micinf.2009.04.011 |
0.365 |
|
| 2009 |
Awasthi A, Kuchroo VK. Th17 cells: From precursors to players in inflammation and infection International Immunology. 21: 489-498. PMID 19261692 DOI: 10.1093/Intimm/Dxp021 |
0.544 |
|
| 2009 |
Beriou G, Costantino CM, Ashley CW, Yang L, Kuchroo VK, Baecher-Allan C, Hafler DA. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood. 113: 4240-9. PMID 19171879 DOI: 10.1182/Blood-2008-10-183251 |
0.443 |
|
| 2009 |
Mariat C, Degauque N, Balasubramanian S, Kenny J, DeKruyff RH, Umetsu DT, Kuchroo V, Zheng XX, Strom TB. Tim-1 Signaling Substitutes for Conventional Signal 1 and Requires Costimulation to Induce T Cell Proliferation Journal of Immunology. 182: 1379-1385. PMID 19155484 DOI: 10.4049/Jimmunol.182.3.1379 |
0.589 |
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| 2009 |
Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 Cells. Annual Review of Immunology. 27: 485-517. PMID 19132915 DOI: 10.1146/Annurev.Immunol.021908.132710 |
0.546 |
|
| 2009 |
Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH, Kuchroo VK. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH -17 cells Nature Immunology. 10: 167-175. PMID 19098919 DOI: 10.1038/Ni.1690 |
0.545 |
|
| 2009 |
Espinosa A, Brauner S, Ambrosi A, Kuchroo V, Wahren-Herlenius M. Response to Comment on “Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF-κB-Dependent Cytokine Expression in Fibroblasts”:
FIGURE 1. The Journal of Immunology. 183: 7620-7621. DOI: 10.4049/Jimmunol.0990104 |
0.317 |
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| 2009 |
Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho I, Khoury S, Oukka M, Kuchroo VK. Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cells Nature Immunology. 10: 551-551. DOI: 10.1038/Ni0509-551B |
0.438 |
|
| 2009 |
Tajima G, O’Leary F, Hanschen M, Ikeda K, Delisle A, Oukka M, Kuchroo V, Lederer J. Regulatory T cells demonstrate an injury-specific recall response Cytokine. 48: 101. DOI: 10.1016/J.Cyto.2009.07.427 |
0.439 |
|
| 2009 |
Francisco L, Salinas V, Brown K, Vanguri V, Freeman G, Kuchroo V, Sharpe A. OR.100. PD-L1 Regulates the Development, Maintenance and Function of Induced-regulatory T Cells Clinical Immunology. 131: S41. DOI: 10.1016/J.Clim.2009.03.115 |
0.403 |
|
| 2009 |
Elyaman W, Bradshaw E, Renauld J, Kuchroo V, Khoury S. OR.78. IL-9 Induces Differentiation of TH17 Cells and Enhances Function of FoxP3+Natural Regulatory T Cells Clinical Immunology. 131: S33. DOI: 10.1016/j.clim.2009.03.093 |
0.462 |
|
| 2009 |
Awasthi A, Dardalhon V, Galileos G, Gao W, Strom T, Sobel R, Ho IC, Oukka M, Kuchroo V. OR.57. IL-4 Inhibits TGF-β-induced Foxp3+T Cells and, Together with TGF-β, Generates IL-9+IL-10+Foxp3-Effector T Cells Clinical Immunology. 131: S25. DOI: 10.1016/J.Clim.2009.03.069 |
0.423 |
|
| 2009 |
Salinas GF, Cantaert T, Nolte M, Bettelli E, Kuchroo V, Tak PP, van Lier R, Baeten D. OR.42. Constitutive Expression of the Costimulatory Molecule CD70 by Non-antigen Specific B Cells is Sufficient to Drive T Cell-driven Autoimmune Disease Clinical Immunology. 131: S20. DOI: 10.1016/J.Clim.2009.03.054 |
0.529 |
|
| 2009 |
Rangachari M, Zhu C, Xiao S, Kuchroo V. OR.36. Bat3 is a Negative Regulator of Tim-3-mediated Th1 Cell Death Clinical Immunology. 131: S17. DOI: 10.1016/J.Clim.2009.03.043 |
0.43 |
|
| 2009 |
Hastings W, Anderson D, Kuchroo V, Hafler D. OR.31. Human TIM-3 Regulates Th1 and Th17 Cytokines Clinical Immunology. 131: S15. DOI: 10.1016/J.Clim.2009.03.038 |
0.376 |
|
| 2008 |
Nagahara K, Arikawa T, Oomizu S, Kontani K, Nobumoto A, Tateno H, Watanabe K, Niki T, Katoh S, Miyake M, Nagahata S, Hirabayashi J, Kuchroo VK, Yamauchi A, Hirashima M. Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions. Journal of Immunology (Baltimore, Md. : 1950). 181: 7660-9. PMID 19017954 DOI: 10.4049/Jimmunol.181.11.7660 |
0.548 |
|
| 2008 |
Anderson AC, Chandwaskar R, Lee DH, Kuchroo VK. Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC. Journal of Immunology (Baltimore, Md. : 1950). 181: 7449-52. PMID 19017931 DOI: 10.4049/Jimmunol.181.11.7449 |
0.544 |
|
| 2008 |
Korn T, Mitsdoerffer M, Croxford AL, Awasthi A, Dardalhon VA, Galileos G, Vollmar P, Stritesky GL, Kaplan MH, Waisman A, Kuchroo VK, Oukka M. IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 18460-5. PMID 19015529 DOI: 10.1073/Pnas.0809850105 |
0.583 |
|
| 2008 |
Hafler DA, Kuchroo V. TIMs: central regulators of immune responses. The Journal of Experimental Medicine. 205: 2699-701. PMID 19015312 DOI: 10.1084/Jem.20082429 |
0.481 |
|
| 2008 |
Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nature Immunology. 9: 1347-55. PMID 18997793 DOI: 10.1038/Ni.1677 |
0.493 |
|
| 2008 |
Awasthi A, Murugaiyan G, Kuchroo VK. Interplay between effector Th17 and regulatory T cells Journal of Clinical Immunology. 28: 660-670. PMID 18810613 DOI: 10.1007/S10875-008-9239-7 |
0.574 |
|
| 2008 |
Xiao S, Jin H, Korn T, Liu SM, Oukka M, Lim B, Kuchroo VK. Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. Journal of Immunology (Baltimore, Md. : 1950). 181: 2277-84. PMID 18684916 DOI: 10.4049/Jimmunol.181.4.2277 |
0.494 |
|
| 2008 |
Laouar Y, Town T, Jeng D, Tran E, Wan Y, Kuchroo VK, Flavell RA. TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 105: 10865-70. PMID 18669656 DOI: 10.1073/Pnas.0805058105 |
0.533 |
|
| 2008 |
Kuchroo VK, Dardalhon V, Xiao S, Anderson AC. New roles for TIM family members in immune regulation. Nature Reviews. Immunology. 8: 577-80. PMID 18617884 DOI: 10.1038/Nri2366 |
0.489 |
|
| 2008 |
Elyaman W, Kivisäkk P, Reddy J, Chitnis T, Raddassi K, Imitola J, Bradshaw E, Kuchroo VK, Yagita H, Sayegh MH, Khoury SJ. Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. The American Journal of Pathology. 173: 411-22. PMID 18583313 DOI: 10.2353/Ajpath.2008.080142 |
0.522 |
|
| 2008 |
Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of T(H)17 cells. Nature. 453: 1051-7. PMID 18563156 DOI: 10.1038/Nature07036 |
0.538 |
|
| 2008 |
Dardalhon V, Korn T, Kuchroo VK, Anderson AC. Role of Th1 and Th17 cells in organ-specific autoimmunity. Journal of Autoimmunity. 31: 252-6. PMID 18502610 DOI: 10.1016/J.Jaut.2008.04.017 |
0.559 |
|
| 2008 |
Chen ML, Yan BS, Bando Y, Kuchroo VK, Weiner HL. Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 180: 7327-37. PMID 18490732 DOI: 10.4049/Jimmunol.180.11.7327 |
0.402 |
|
| 2008 |
Yang L, Anderson DE, Baecher-Allan C, Hastings WD, Bettelli E, Oukka M, Kuchroo VK, Hafler DA. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature. 454: 350-2. PMID 18469800 DOI: 10.1038/Nature07021 |
0.5 |
|
| 2008 |
Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW. Functional Th1 cells are required for surgical adhesion formation in a murine model. Journal of Immunology (Baltimore, Md. : 1950). 180: 6970-6. PMID 18453619 DOI: 10.4049/Jimmunol.180.10.6970 |
0.538 |
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| 2008 |
Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 expressed on APCs induces T cell expansion and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 4706-13. PMID 18354194 DOI: 10.4049/Jimmunol.180.7.4706 |
0.823 |
|
| 2008 |
Seki M, Oomizu S, Sakata Km, Sakata A, Arikawa T, Watanabe K, Ito K, Takeshita K, Niki T, Saita N, Nishi N, Yamauchi A, Katoh S, Matsukawa A, Kuchroo V, et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis Clinical Immunology. 127: 78-88. PMID 18282810 DOI: 10.1016/J.Clim.2008.01.006 |
0.612 |
|
| 2008 |
Degauque N, Mariat C, Kenny J, Zhang D, Gao W, Vu MD, Alexopoulos S, Oukka M, Umetsu DT, DeKruyff RH, Kuchroo V, Zheng XX, Strom TB. Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. The Journal of Clinical Investigation. 118: 735-41. PMID 18079964 DOI: 10.1172/Jci32562 |
0.581 |
|
| 2008 |
Strandberg L, Ambrosi A, Espinosa A, Ottosson L, Eloranta ML, Zhou W, Elfving A, Greenfield E, Kuchroo VK, Wahren-Herlenius M. Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies. Journal of Clinical Immunology. 28: 220-31. PMID 18071879 DOI: 10.1007/S10875-007-9157-0 |
0.317 |
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| 2008 |
Xiao S, Kuchroo VK. Promotion of proinflammatory Th1 and Th17 responses by Tim-1 expressed on dendritic cells The Faseb Journal. 22: 459-459. DOI: 10.1096/Fasebj.22.2_Supplement.459 |
0.455 |
|
| 2008 |
Tajima G, MacConmara M, O’Leary F, Stallwood C, Delisle A, Goode T, Kearney M, Kuchroo V, Mannick J, Lederer J. QS379. Injury Activates and Expands Regulatory T Cells Journal of Surgical Research. 144: 418. DOI: 10.1016/J.Jss.2007.12.633 |
0.432 |
|
| 2008 |
Baecher-Allan C, Beriou G, Yang L, Hastings W, Anderson D, Kuchroo VK, Hafler DA. SY-23 Human CD4+CD25high natural Tregs and Th17 effector cells are related Cytokine. 43: 305. DOI: 10.1016/J.Cyto.2008.07.340 |
0.444 |
|
| 2008 |
Liu S, Zhang Z, Oukka M, Kuchroo V. Sa.107. Mice Overexpressing the Truncated 1/4 CTLA-4 Isoform Have Hyperactive T Cells and Accumulate Memory Cells Without Developing Spontaneous Autoimmune Disease Clinical Immunology. 127: S115-S116. DOI: 10.1016/J.Clim.2008.03.328 |
0.474 |
|
| 2008 |
Xiao S, Jin H, Liu S, Korn T, Oukka M, Lim B, Kuchroo V. F.37. Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF-b-driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression Clinical Immunology. 127: S55. DOI: 10.1016/J.Clim.2008.03.149 |
0.465 |
|
| 2008 |
Oukka M, Korn T, Awasthi A, Dardalhon V, Galileos G, Riol Blanco L, Kuchroo V, Bettelli E. OR.98. IL-23 Receptor (IL-23R) GFP Reporter Mice Reveal New Populations of IL-17-producing and IL-23-responsive Cells Clinical Immunology. 127: S39. DOI: 10.1016/J.Clim.2008.03.105 |
0.328 |
|
| 2008 |
Korn T, Mitsdoerffer M, Awasthi A, Galileos G, Oukka M, Kuchroo V. OR.44. Incomplete Freund's Adjuvant Skews the Balance Between TH17 and Foxp3+ T-regs and Induces Antigen-specific Tolerance Due to the Lack of IL-6 Induction Clinical Immunology. 127: S19-S20. DOI: 10.1016/J.Clim.2008.03.050 |
0.475 |
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| 2008 |
Anderson D, Yang L, Baecher-Allan C, Bettelli E, Oukka M, Kuchroo V, Hafler D. OR.41. IL-21 and TGF-β are Required for Differentiation of Human Th17 Cells Clinical Immunology. 127: S18-S19. DOI: 10.1016/J.Clim.2008.03.047 |
0.371 |
|
| 2008 |
Dardalhon V, Anderson A, Karman J, Chandwaskar R, Lee D, Cornejo M, Nishi N, Yamauchi A, Sobel R, Hirashima M, Kuchroo V. OR.26. Tim-3:Galectin-9 Pathway Expands Myeloid Suppressor Cells Clinical Immunology. 127: S12. DOI: 10.1016/J.Clim.2008.03.031 |
0.397 |
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| 2008 |
Xiao S, Kuchroo V. OR.25. Promotion of Proinflammatory Th1 and Th17 Responses by Tim-1 Expressed on Dendritic Cells Clinical Immunology. 127: S12. DOI: 10.1016/J.Clim.2008.03.030 |
0.455 |
|
| 2007 |
Korn T, Oukka M, Kuchroo V, Bettelli E. Th17 cells: effector T cells with inflammatory properties. Seminars in Immunology. 19: 362-71. PMID 18035554 DOI: 10.1016/J.Smim.2007.10.007 |
0.576 |
|
| 2007 |
Anderson AC, Anderson DE, Bregoli L, Hastings WD, Kassam N, Lei C, Chandwaskar R, Karman J, Su EW, Hirashima M, Bruce JN, Kane LP, Kuchroo VK, Hafler DA. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science (New York, N.Y.). 318: 1141-3. PMID 18006747 DOI: 10.1126/Science.1148536 |
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| 2007 |
Awasthi A, Carrier Y, Peron JPS, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M, Weiner HL. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells Nature Immunology. 8: 1380-1389. PMID 17994022 DOI: 10.1038/Ni1541 |
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| 2007 |
Zhu B, Bando Y, Xiao S, Yang K, Anderson AC, Kuchroo VK, Khoury SJ. CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 5228-37. PMID 17911608 DOI: 10.4049/Jimmunol.179.8.5228 |
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| 2007 |
Illés Z, Waldner H, Reddy J, Anderson AC, Sobel RA, Kuchroo VK. Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background. International Immunology. 19: 1235-48. PMID 17804690 DOI: 10.1093/Intimm/Dxm094 |
0.533 |
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| 2007 |
Bettelli E, Korn T, Kuchroo VK. Th17: the third member of the effector T cell trilogy. Current Opinion in Immunology. 19: 652-7. PMID 17766098 DOI: 10.1016/J.Coi.2007.07.020 |
0.556 |
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| 2007 |
Degauque N, Mariat C, Kenny J, Sanchez-Fueyo A, Alexopoulos SP, Kuchroo V, Zheng XX, Strom TB. Regulation of T-cell immunity by T-cell immunoglobulin and mucin domain proteins. Transplantation. 84: S12-6. PMID 17632405 DOI: 10.1097/01.Tp.0000269111.87719.D8 |
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Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, ... ... Kuchroo VK, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. The Journal of Experimental Medicine. 204: 1691-702. PMID 17606630 DOI: 10.1084/Jem.20062498 |
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| 2007 |
Korn T, Bettelli E, Gao W, Awasthi A, Jäger A, Strom TB, Oukka M, Kuchroo VK. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 448: 484-487. PMID 17581588 DOI: 10.1038/Nature05970 |
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| 2007 |
Greve B, Weissert R, Hamdi N, Bettelli E, Sobel RA, Coyle A, Kuchroo VK, Rajewsky K, Schmidt-Supprian M. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 179-85. PMID 17579036 DOI: 10.4049/Jimmunol.179.1.179 |
0.55 |
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| 2007 |
Gao W, Lu Y, El Essawy B, Oukka M, Kuchroo VK, Strom TB. Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 1722-32. PMID 17511761 DOI: 10.1111/J.1600-6143.2007.01842.X |
0.54 |
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| 2007 |
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. The Journal of Experimental Medicine. 204: 1257-65. PMID 17502665 DOI: 10.1084/Jem.20062512 |
0.518 |
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| 2007 |
Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nature Medicine. 13: 423-31. PMID 17384649 DOI: 10.1038/Nm1564 |
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| 2007 |
Anderson AC, Xiao S, Kuchroo VK. Tim protein structures reveal a unique face for ligand binding. Immunity. 26: 273-5. PMID 17376389 DOI: 10.1016/J.Immuni.2007.03.004 |
0.326 |
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| 2007 |
Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nature Immunology. 8: 345-50. PMID 17375096 DOI: 10.1038/Ni0407-345 |
0.533 |
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| 2007 |
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-β T cell-transgenic mice Journal of Immunology. 178: 179-185. PMID 17182553 DOI: 10.4049/Jimmunol.178.1.179 |
0.51 |
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| 2007 |
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. II. TGF-β-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity Journal of Immunology. 178: 172-178. PMID 17182552 DOI: 10.4049/Jimmunol.178.1.172 |
0.518 |
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Manzanet RR, Hartt-Meyers J, Slavik J, Dardalhon V, Kassam N, Greenfield EA, Sobel RA, Strom TB, Hafler DA, Kuchroo VK. Tim-4 Expressed on Antigen-presenting Cells Induces T Cell Expansion and Survival Clinical Immunology. 123: S124-S125. DOI: 10.1016/J.Clim.2007.03.533 |
0.516 |
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| 2007 |
Hastings W, Greer A, Kuchroo V, Hafler D, Kent S, Anderson D. Dysregulation of the TIM-3-Galectin-9 Pathway in Type I Diabetic T Cells Clinical Immunology. 123: S21. DOI: 10.1016/J.Clim.2007.03.228 |
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| 2007 |
Chung D, Korn T, Richard J, Kohm A, Ruzek M, Oukka M, Miller S, Nahill S, Kuchroo V. Anti-Thymocyte Globulin Prevents Autoimmune Encephalomyelitis by Expanding Myelin Antigen Specific Foxp3+ Regulatory T Cells Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.200 |
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Korn T, Oukka M, Reddy J, Bettelli E, Awasthi A, Sobel R, Wucherpfennig K, Kuchroo V. Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation Clinical Immunology. 123: S152-S153. DOI: 10.1016/J.Clim.2007.03.073 |
0.542 |
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| 2007 |
Yang L, Anderson DE, Kuchroo VK, Hafler DA. Defect in TIM-3 Regulation of CD4+ T Cells in a Human Autoimmune Disease Clinical Immunology. 123: S139-S140. DOI: 10.1016/J.Clim.2007.03.035 |
0.49 |
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Bettelli E, Baeten D, Jäger A, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of Clinical Investigation. 116: 2393-402. PMID 16955141 DOI: 10.1172/Jci28334 |
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Kuchroo VK, Meyers JH, Umetsu DT, DeKruyff RH. TIM family of genes in immunity and tolerance. Advances in Immunology. 91: 227-49. PMID 16938542 DOI: 10.1016/S0065-2776(06)91006-2 |
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Koguchi K, Anderson DE, Yang L, O'Connor KC, Kuchroo VK, Hafler DA. Dysregulated T cell expression of TIM3 in multiple sclerosis. The Journal of Experimental Medicine. 203: 1413-8. PMID 16754722 DOI: 10.1084/Jem.20060210 |
0.526 |
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Espinosa A, Zhou W, Ek M, Hedlund M, Brauner S, Popovic K, Horvath L, Wallerskog T, Oukka M, Nyberg F, Kuchroo VK, Wahren-Herlenius M. The Sjogren's syndrome-associated autoantigen Ro52 is an E3 ligase that regulates proliferation and cell death. Journal of Immunology (Baltimore, Md. : 1950). 176: 6277-85. PMID 16670339 DOI: 10.4049/Jimmunol.176.10.6277 |
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Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature. 441: 235-238. PMID 16648838 DOI: 10.1038/Nature04753 |
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Waldner H, Sobel RA, Price N, Kuchroo VK. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 5455-62. PMID 16622013 DOI: 10.4049/Jimmunol.176.9.5455 |
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Zhang X, Reddy J, Ochi H, Frenkel D, Kuchroo VK, Weiner HL. Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells. International Immunology. 18: 495-503. PMID 16540527 DOI: 10.1093/Intimm/Dxh390 |
0.46 |
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Dardalhon V, Schubart AS, Kuchroo VK. Response to Comment on “CD226 Is Specifically Expressed on the Surface of Th1 Cells and Regulates Their Expansion and Effector Functions” The Journal of Immunology. 176: 3856.1-3856. DOI: 10.4049/Jimmunol.176.7.3856 |
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Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Anderson A, Zhang Z, Gutierrez C, Sobel R, Umetsu D, Yagita H, Akiba H, Sayegh M, DeKruyff R, Khoury S, ... Kuchroo V, et al. TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity Clinical Immunology. 119: S44-S45. DOI: 10.1016/J.Clim.2006.04.412 |
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| 2006 |
Hastings W, Kent S, Kuchroo V, Hafler D. Analysis of Autoreactive T-Cells in Type I Diabetes Clinical Immunology. 119: S44. DOI: 10.1016/J.Clim.2006.04.411 |
0.395 |
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Korn T, Reddy J, Gao W, Strom T, Oukka M, Kuchroo V. OR.76. Myelin Specific Regulatory T-Cells Expand from Naturally Occurring Regulatory T-Cells and Accumulate in the Cns during EAE Clinical Immunology. 119: S33. DOI: 10.1016/J.Clim.2006.04.381 |
0.528 |
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Zhu C, Anderson A, Zhang Z, Xiao S, Schubart A, Xiong H, Imitola J, Khoury S, Xiao Zheng X, Strom T, Kuchroo V. Sa.15. The TIM-3 and its Ligand Mediated Signaling Negatively Regulates T Helper Type 1 Immunity Clinical Immunology. 119: S110. DOI: 10.1016/J.Clim.2006.04.247 |
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Miyamoto K, Kingsley CI, Zhang X, Jabs C, Izikson L, Sobel RA, Weiner HL, Kuchroo VK, Sharpe AH. The ICOS molecule plays a crucial role in the development of mucosal tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 7341-7. PMID 16301640 DOI: 10.4049/Jimmunol.175.11.7341 |
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Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, Zheng XX, Strom TB, Kuchroo VK. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nature Immunology. 6: 1245-52. PMID 16286920 DOI: 10.1038/Ni1271 |
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Illes Z, Stern JN, Keskin DB, Reddy J, Brosnan CF, Waldner H, Santambrogio L, Kuchroo VK, Strominger JL. Copolymer effects on microglia and T cells in the central nervous system of humanized mice. European Journal of Immunology. 35: 3683-93. PMID 16259003 DOI: 10.1002/Eji.200526121 |
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Reddy J, Waldner H, Zhang X, Illes Z, Wucherpfennig KW, Sobel RA, Kuchroo VK. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 5591-5. PMID 16237044 DOI: 10.4049/Jimmunol.175.9.5591 |
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Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Tim-2 regulates T helper type 2 responses and autoimmunity. The Journal of Experimental Medicine. 202: 437-44. PMID 16043519 DOI: 10.1084/Jem.20050308 |
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Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. Journal of Immunology (Baltimore, Md. : 1950). 175: 1558-65. PMID 16034094 DOI: 10.4049/Jimmunol.175.3.1558 |
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Illés Z, Waldner H, Reddy J, Bettelli E, Nicholson LB, Kuchroo VK. T cell tolerance induced by cross-reactive TCR ligands can be broken by superagonist resulting in anti-inflammatory T cell cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 175: 1491-7. PMID 16034086 DOI: 10.4049/Jimmunol.175.3.1491 |
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Meyers JH, Sabatos CA, Chakravarti S, Kuchroo VK. The TIM gene family regulates autoimmune and allergic diseases. Trends in Molecular Medicine. 11: 362-9. PMID 16002337 DOI: 10.1016/J.Molmed.2005.06.008 |
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Vijayakrishnan L, Slavik JM, Illés Z, Rainbow D, Peterson LB, Sharpe AS, Wicker LS, Kuchroo VK. An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells. Novartis Foundation Symposium. 267: 200-12; discussion 2. PMID 15999808 DOI: 10.1002/047002139X.Ch13 |
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Yu P, Gregg RK, Bell JJ, Ellis JS, Divekar R, Lee HH, Jain R, Waldner H, Hardaway JC, Collins M, Kuchroo VK, Zaghouani H. Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigen. Journal of Immunology (Baltimore, Md. : 1950). 174: 6772-80. PMID 15905518 DOI: 10.4049/Jimmunol.174.11.6772 |
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Meyers JH, Chakravarti S, Schlesinger D, Illes Z, Waldner H, Umetsu SE, Kenny J, Zheng XX, Umetsu DT, DeKruyff RH, Strom TB, Kuchroo VK. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation. Nature Immunology. 6: 455-64. PMID 15793576 DOI: 10.1038/Ni1185 |
0.826 |
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Ellmerich S, Mycko M, Takacs K, Waldner H, Wahid FN, Boyton RJ, King RH, Smith PA, Amor S, Herlihy AH, Hewitt RE, Jutton M, Price DA, Hafler DA, Kuchroo VK, et al. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. Journal of Immunology (Baltimore, Md. : 1950). 174: 1938-46. PMID 15699121 DOI: 10.4049/Jimmunol.174.4.1938 |
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Stern JN, Illés Z, Reddy J, Keskin DB, Fridkis-Hareli M, Kuchroo VK, Strominger JL. Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration of experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 102: 1620-5. PMID 15665083 DOI: 10.1073/Pnas.0409022102 |
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Bettelli E, Kuchroo VK. IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together. The Journal of Experimental Medicine. 201: 169-71. PMID 15657286 DOI: 10.1084/Jem.20042279 |
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Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Correction Journal of Experimental Medicine. 202: 877-877. DOI: 10.1084/Jem.20050308082505C |
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Reddy J, Illes Z, Zhang X, Encinas J, Pyrdol J, Nicholson L, Sobel RA, Wucherpfennig KW, Kuchroo VK. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15434-9. PMID 15492218 DOI: 10.1073/Pnas.0404444101 |
0.46 |
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Tadokoro CE, Vallochi AL, Rios LS, Martins GA, Schlesinger D, Mosca T, Kuchroo VK, Rizzo LV, Abrahamsohn IA. Experimental autoimmune encephalomyelitis can be prevented and cured by infection with Trypanosoma cruzi. Journal of Autoimmunity. 23: 103-15. PMID 15324929 DOI: 10.1016/J.Jaut.2004.05.003 |
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| 2004 |
Stern JN, Illés Z, Reddy J, Keskin DB, Sheu E, Fridkis-Hareli M, Nishimura H, Brosnan CF, Santambrogio L, Kuchroo VK, Strominger JL. Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 101: 11743-8. PMID 15292514 DOI: 10.1073/Pnas.0403832101 |
0.505 |
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Illés Z, Stern JN, Reddy J, Waldner H, Mycko MP, Brosnan CF, Ellmerich S, Altmann DM, Santambrogio L, Strominger JL, Kuchroo VK. Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 11749-54. PMID 15292513 DOI: 10.1073/Pnas.0403833101 |
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Mycko MP, Waldner H, Anderson DE, Bourcier KD, Wucherpfennig KW, Kuchroo VK, Hafler DA. Cross-reactive TCR responses to self antigens presented by different MHC class II molecules. Journal of Immunology (Baltimore, Md. : 1950). 173: 1689-98. PMID 15265898 DOI: 10.4049/Jimmunol.173.3.1689 |
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Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, Kuchroo VK, Freeman GJ, Sharpe AH. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 10691-6. PMID 15249675 DOI: 10.1073/Pnas.0307252101 |
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Anderson AC, Reddy J, Nazareno R, Sobel RA, Nicholson LB, Kuchroo VK. IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 828-34. PMID 15240669 DOI: 10.4049/Jimmunol.173.2.828 |
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Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/Jem.20031819 |
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Ellmerich S, Takacs K, Mycko M, Waldner H, Wahid F, Boyton RJ, Smith PA, Amor S, Baker D, Hafler DA, Kuchroo VK, Altmann DM. Disease-related epitope spread in a humanized T cell receptor transgenic model of multiple sclerosis. European Journal of Immunology. 34: 1839-48. PMID 15214032 DOI: 10.1002/Eji.200324044 |
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Greve B, Reddy J, Waldner HP, Sobel RA, Kuchroo VK. Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes. European Journal of Immunology. 34: 1828-38. PMID 15214031 DOI: 10.1002/Eji.200425116 |
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| 2004 |
Greve B, Vijayakrishnan L, Kubal A, Sobel RA, Peterson LB, Wicker LS, Kuchroo VK. The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 157-63. PMID 15210770 DOI: 10.4049/Jimmunol.173.1.157 |
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Hawiger D, Masilamani RF, Bettelli E, Kuchroo VK, Nussenzweig MC. Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity. 20: 695-705. PMID 15189735 DOI: 10.1016/J.Immuni.2004.05.002 |
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Khademi M, Illés Z, Gielen AW, Marta M, Takazawa N, Baecher-Allan C, Brundin L, Hannerz J, Martin C, Harris RA, Hafler DA, Kuchroo VK, Olsson T, Piehl F, Wallström E. T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis Journal of Immunology. 172: 7169-7176. PMID 15153541 DOI: 10.4049/Jimmunol.172.11.7169 |
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Petersen TR, Gülland S, Bettelli E, Kuchroo V, Palmer E, Bäckström BT. A chimeric T cell receptor with super-signaling properties International Immunology. 16: 889-894. PMID 15148288 DOI: 10.1093/Intimm/Dxh098 |
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Vijayakrishnan L, Slavik JM, Illés Z, Greenwald RJ, Rainbow D, Greve B, Peterson LB, Hafler DA, Freeman GJ, Sharpe AH, Wicker LS, Kuchroo VK. An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells. Immunity. 20: 563-75. PMID 15142525 DOI: 10.1016/S1074-7613(04)00110-4 |
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Waldner H, Collins M, Kuchroo VK. Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. The Journal of Clinical Investigation. 113: 990-7. PMID 15057305 DOI: 10.1172/Jci19388 |
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Petersen TR, Bettelli E, Sidney J, Sette A, Kuchroo V, Bäckström BT. Characterization of MHC- and TCR-binding residues of the myelin oligodendrocyte glycoprotein 38-51 peptide European Journal of Immunology. 34: 165-173. PMID 14971042 DOI: 10.1002/Eji.200324669 |
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Zhang X, Koldzic DN, Izikson L, Reddy J, Nazareno RF, Sakaguchi S, Kuchroo VK, Weiner HL. IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells. International Immunology. 16: 249-56. PMID 14734610 DOI: 10.1093/Intimm/Dxh029 |
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Bettelli E, Nicholson LB, Kuchroo VK. IL-10, a key effector regulatory cytokine in experimental autoimmune encephalomyelitis. Journal of Autoimmunity. 20: 265-7. PMID 12791309 DOI: 10.1016/S0896-8411(03)00048-9 |
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Sabatos CA, Chakravarti S, Cha E, Schubart A, Sánchez-Fueyo A, Zheng XX, Coyle AJ, Strom TB, Freeman GJ, Kuchroo VK. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nature Immunology. 4: 1102-10. PMID 14556006 DOI: 10.1038/Ni988 |
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Sánchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, Manlongat N, Bender O, Kamradt T, Kuchroo VK, Gutiérrez-Ramos JC, Coyle AJ, Strom TB. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance Nature Immunology. 4: 1093-1101. PMID 14556005 DOI: 10.1038/Ni987 |
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Robinson WH, Fontoura P, Lee BJ, de Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, ... Kuchroo VK, et al. Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nature Biotechnology. 21: 1033-9. PMID 12910246 DOI: 10.1038/Nbt859 |
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Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. European Journal of Immunology. 33: 2022-2032. PMID 12884869 DOI: 10.1002/Eji.200323180 |
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Kuchroo VK, Umetsu DT, DeKruyff RH, Freeman GJ. The TIM gene family: emerging roles in immunity and disease Nature Reviews Immunology. 3: 454-462. PMID 12776205 DOI: 10.1038/Nri1111 |
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Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of Experimental Medicine. 197: 1073-81. PMID 12732654 DOI: 10.1084/Jem.20021603 |
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|
| 2003 |
Reddy J, Bettelli E, Nicholson L, Waldner H, Jang MH, Wucherpfennig KW, Kuchroo VK. Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers. Journal of Immunology (Baltimore, Md. : 1950). 170: 870-7. PMID 12517952 DOI: 10.4049/Jimmunol.170.2.870 |
0.511 |
|
| 2003 |
Wahren-Herlenius M, Kuchroo VK. Killers come to the rescue. Nature Biotechnology. 20: 1205-6. PMID 12454670 DOI: 10.1038/Nbt1202-1205 |
0.531 |
|
| 2003 |
Munder M, Bettelli E, Monney L, Slavik JM, Nicholson LB, Kuchroo VK. Reduced self-reactivity of an autoreactive T cell after activation with cross-reactive non-self-ligand. The Journal of Experimental Medicine. 196: 1151-62. PMID 12417626 DOI: 10.1084/Jem.20020390 |
0.495 |
|
| 2002 |
Meyers JH, Ryu A, Monney L, Nguyen K, Greenfield EA, Freeman GJ, Kuchroo VK. Cutting edge: CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions. Journal of Immunology (Baltimore, Md. : 1950). 169: 5382-6. PMID 12421909 DOI: 10.4049/Jimmunol.169.10.5382 |
0.808 |
|
| 2002 |
Howie D, Okamoto S, Rietdijk S, Clarke K, Wang N, Gullo C, Bruggeman JP, Manning S, Coyle AJ, Greenfield E, Kuchroo V, Terhorst C. The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. Blood. 100: 2899-907. PMID 12351401 DOI: 10.1182/Blood-2002-02-0445 |
0.539 |
|
| 2002 |
Freeman GJ, Sharpe AH, Kuchroo VK. Protect the killer: CTLS need defenses against the tumor Nature Medicine. 8: 787-789. PMID 12152031 DOI: 10.1038/Nm0802-787 |
0.43 |
|
| 2002 |
Baroja ML, Vijayakrishnan L, Bettelli E, Darlington PJ, Chau TA, Ling V, Collins M, Carreno BM, Madrenas J, Kuchroo VK. Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A. Journal of Immunology (Baltimore, Md. : 1950). 168: 5070-8. PMID 11994459 DOI: 10.4049/Jimmunol.168.10.5070 |
0.304 |
|
| 2002 |
Chang TT, Kuchroo VK, Sharpe AH. Role of the B7-CD28/CTLA-4 pathway in autoimmune disease. Current Directions in Autoimmunity. 5: 113-30. PMID 11826754 DOI: 10.1159/000060550 |
0.335 |
|
| 2002 |
Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 415: 536-41. PMID 11823861 DOI: 10.1038/415536A |
0.847 |
|
| 2001 |
Kuchroo VK, Anderson AC, Waldner H, Munder M, Bettelli E, Nicholson LB. T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire. Annual Review of Immunology. 20: 101-23. PMID 11861599 DOI: 10.1146/Annurev.Immunol.20.081701.141316 |
0.545 |
|
| 2001 |
Gaglia JL, Mattoo A, Greenfield EA, Freeman GJ, Kuchroo VK. Characterization of endogenous Chinese hamster ovary cell surface molecules that mediate T cell costimulation. Cellular Immunology. 213: 83-93. PMID 11831870 DOI: 10.1006/Cimm.2001.1867 |
0.504 |
|
| 2001 |
McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, Freeman GJ, Umetsu DT, DeKruyff RH. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nature Immunology. 2: 1109-16. PMID 11725301 DOI: 10.1038/Ni739 |
0.42 |
|
| 2001 |
Stremmel C, Exley M, Balk S, Hohenberger W, Kuchroo VK. Characterization of the phenotype and function of CD8(+), alpha / beta(+) NKT cells from tumor-bearing mice that show a natural killer cell activity and lyse multiple tumor targets. European Journal of Immunology. 31: 2818-28. PMID 11536181 DOI: 10.1002/1521-4141(200109)31:9<2818::Aid-Immu2818>3.0.Co;2-1 |
0.558 |
|
| 2001 |
Anderson AC, Nicholson LB, Kuchroo VK. The origin and regulation of autopathogenic T cells. Journal of Clinical Immunology. 21: 74-80. PMID 11332656 DOI: 10.1023/A:1011027020890 |
0.545 |
|
| 2001 |
Theien BE, Vanderlugt CL, Eagar TN, Nickerson-Nutter C, Nazareno R, Kuchroo VK, Miller SD. Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. 107: 995-1006. PMID 11306603 DOI: 10.1172/Jci11717 |
0.477 |
|
| 2001 |
Nicholson LB, Kuchroo VK. Selecting killers: the line between life and death. Nature Immunology. 1: 192-4. PMID 10973273 DOI: 10.1038/79726 |
0.488 |
|
| 2001 |
Yoles E, Hauben E, Palgi O, Agranov E, Gothilf A, Cohen A, Kuchroo V, Cohen IR, Weiner H, Schwartz M. Protective Autoimmunity Is a Physiological Response to CNS Trauma The Journal of Neuroscience. 21: 3740-3748. DOI: 10.1523/Jneurosci.21-11-03740.2001 |
0.377 |
|
| 2000 |
Gaglia JL, Greenfield EA, Mattoo A, Sharpe AH, Freeman GJ, Kuchroo VK. Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells Journal of Immunology. 165: 6091-6098. PMID 11086041 DOI: 10.4049/Jimmunol.165.11.6091 |
0.503 |
|
| 2000 |
McAdam AJ, Chang TT, Lumelsky AE, Greenfield EA, Boussiotis VA, Duke-Cohan JS, Chernova T, Malenkovich N, Jabs C, Kuchroo VK, Ling V, Collins M, Sharpe AH, Freeman GJ. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 5035-40. PMID 11046032 DOI: 10.4049/Jimmunol.165.9.5035 |
0.497 |
|
| 2000 |
Anderson AC, Waldner H, Turchin V, Jabs C, Prabhu Das M, Kuchroo VK, Nicholson LB. Autoantigen-responsive T cell clones demonstrate unfocused TCR cross-reactivity toward multiple related ligands: implications for autoimmunity. Cellular Immunology. 202: 88-96. PMID 10896768 DOI: 10.1006/Cimm.2000.1660 |
0.432 |
|
| 2000 |
Waldner H, Whitters MJ, Sobel RA, Collins M, Kuchroo VK. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 3412-7. PMID 10737797 DOI: 10.1073/Pnas.97.7.3412 |
0.502 |
|
| 2000 |
Young DA, Lowe LD, Booth SS, Whitters MJ, Nicholson L, Kuchroo VK, Collins M. IL-4, IL-10, IL-13, and TGF-beta from an altered peptide ligand-specific Th2 cell clone down-regulate adoptive transfer of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 164: 3563-72. PMID 10725711 DOI: 10.4049/Jimmunol.164.7.3563 |
0.436 |
|
| 2000 |
Anderson AC, Nicholson LB, Legge KL, Turchin V, Zaghouani H, Kuchroo VK. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire. The Journal of Experimental Medicine. 191: 761-70. PMID 10704458 DOI: 10.1084/Jem.191.5.761 |
0.494 |
|
| 2000 |
Nicholson LB, Anderson AC, Kuchroo VK. Tuning T cell activation threshold and effector function with cross-reactive peptide ligands. International Immunology. 12: 205-13. PMID 10653856 DOI: 10.1093/Intimm/12.2.205 |
0.506 |
|
| 1999 |
Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 190: 733-40. PMID 10477557 DOI: 10.1084/Jem.190.5.733 |
0.448 |
|
| 1999 |
Maron R, Hancock WW, Slavin A, Hattori M, Kuchroo V, Weiner HL. Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines. International Immunology. 11: 1573-80. PMID 10464178 DOI: 10.1093/Intimm/11.9.1573 |
0.407 |
|
| 1999 |
Murtaza A, Kuchroo VK, Freeman GJ. Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands. International Immunology. 11: 407-16. PMID 10221652 DOI: 10.1093/Intimm/11.3.407 |
0.497 |
|
| 1999 |
Stremmel C, Greenfield EA, Howard E, Freeman GJ, Kuchroo VK. B7-2 expressed on EL4 lymphoma suppresses antitumor immunity by an interleukin 4-dependent mechanism Journal of Experimental Medicine. 189: 919-930. PMID 10075975 DOI: 10.1084/Jem.189.6.919 |
0.463 |
|
| 1998 |
Kuchroo VK, Weiner HL. Antigen-driven regulation of experimental autoimmune encephalomyelitis Research in Immunology. 149: 759-771. PMID 9923631 DOI: 10.1016/S0923-2494(99)80003-0 |
0.34 |
|
| 1998 |
Greenfield EA, Nguyen KA, Kuchroo VK. CD28/B7 costimulation: A review Critical Reviews in Immunology. 18: 389-418. PMID 9784967 DOI: 10.1615/Critrevimmunol.V18.I5.10 |
0.498 |
|
| 1998 |
Carrizosa AM, Nicholson LB, Farzan M, Southwood S, Sette A, Sobel RA, Kuchroo VK. Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen. Journal of Immunology (Baltimore, Md. : 1950). 161: 3307-14. PMID 9759846 DOI: 10.1016/S0165-5728(98)91376-5 |
0.406 |
|
| 1998 |
Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 161: 3299-306. PMID 9759845 DOI: 10.1016/S0165-5728(98)91500-4 |
0.379 |
|
| 1998 |
Nicholson LB, Waldner H, Carrizosa AM, Sette A, Collins M, Kuchroo VK. Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: implications for autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 95: 264-9. PMID 9419364 DOI: 10.1073/Pnas.95.1.264 |
0.493 |
|
| 1998 |
Young DA, Lowe LD, Booth SS, Whitters M, Kuchroo VK, Collins M. Role of Th2 cytokines in adoptive transfer of EAE Journal of Neuroimmunology. 90: 86. DOI: 10.1016/S0165-5728(98)91695-2 |
0.351 |
|
| 1998 |
Nicholson L, Carrizosa A, Turchin V, Kuchroo V. Autoantigen specific cross-reactive T cell clones adapt to superagonist ligands by modulating the co-receptor CD4 Journal of Neuroimmunology. 90: 18. DOI: 10.1016/S0165-5728(98)91286-3 |
0.453 |
|
| 1997 |
Das MP, Nicholson LB, Greer JM, Kuchroo VK. Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein. The Journal of Experimental Medicine. 186: 867-76. PMID 9294141 DOI: 10.1084/Jem.186.6.867 |
0.411 |
|
| 1997 |
Nicholson LB, Murtaza A, Hafler BP, Sette A, Kuchroo VK. A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens. Proceedings of the National Academy of Sciences of the United States of America. 94: 9279-84. PMID 9256473 DOI: 10.1073/Pnas.94.17.9279 |
0.448 |
|
| 1997 |
Nicholson LB, Kuchroo VK. Manipulation of the Th1/Th2 balance in autoimmune disease. Current Opinion in Immunology. 8: 837-42. PMID 8994864 DOI: 10.1016/S0952-7915(96)80013-6 |
0.517 |
|
| 1997 |
Encinas JA, Weiner HL, Kuchroo VK. Inheritance of susceptibility to experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 45: 655-69. PMID 8892077 DOI: 10.1002/(Sici)1097-4547(19960915)45:6<655::Aid-Jnr2>3.0.Co;2-7 |
0.319 |
|
| 1997 |
Hafler DA, Saadeh MG, Kuchroo VK, Milford E, Steinman L. TCR usage in human and experimental demyelinating disease. Immunology Today. 17: 152-9. PMID 8871344 DOI: 10.1016/0167-5699(96)80611-6 |
0.481 |
|
| 1996 |
Ausubel LJ, Kwan CK, Sette A, Kuchroo V, Hafler DA. Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones. Proceedings of the National Academy of Sciences of the United States of America. 93: 15317-22. PMID 8986809 DOI: 10.1073/Pnas.93.26.15317 |
0.436 |
|
| 1996 |
Prabhu Das MR, Cohen A, Zamvil SS, Offner H, Kuchroo VK. Prior exposure to superantigen can inhibit or exacerbate autoimmune encephalomyelitis: T-cell repertoire engaged by the autoantigen determines clinical outcome Journal of Neuroimmunology. 71: 3-10. PMID 8982096 DOI: 10.1016/S0165-5728(96)00107-5 |
0.486 |
|
| 1996 |
Windhagen A, Nicholson LB, Weiner HL, Kuchroo VK, Hafler DA. Role of Th1 and Th2 cells in neurologic disorders. Chemical Immunology. 63: 171-86. PMID 8934837 DOI: 10.1159/000319485 |
0.396 |
|
| 1996 |
Ranger AM, Das MP, Kuchroo VK, Glimcher LH. B7-2 (CD86) is essential for the development of IL-4-producing T cells International Immunology. 8: 1549-1560. PMID 8921434 DOI: 10.1093/Intimm/8.10.1549 |
0.49 |
|
| 1996 |
Chen Y, Inobe JI, Kuchroo VK, Baron JL, Janeway CA, Weiner HL. Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells Proceedings of the National Academy of Sciences of the United States of America. 93: 388-391. PMID 8552644 DOI: 10.1073/Pnas.93.1.388 |
0.523 |
|
| 1995 |
Chen Y, Inobe J, Marks R, Gonnella P, Kuchroo VK, Weiner HL. Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature. 376: 177-80. PMID 7603570 DOI: 10.1038/376177A0 |
0.517 |
|
| 1995 |
Nicholson LB, Greer JM, Sobel RA, Lees MB, Kuchroo VK. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity. 3: 397-405. PMID 7584131 DOI: 10.1016/1074-7613(95)90169-8 |
0.475 |
|
| 1995 |
Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6 |
0.443 |
|
| 1995 |
Prabhu Das MR, Zamvil SS, Borriello F, Weiner HL, Sharpe AH, Kuchroo VK. Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation European Journal of Immunology. 25: 207-211. PMID 7531145 DOI: 10.1002/Eji.1830250134 |
0.46 |
|
| 1995 |
Chen Y, Inobe J, Marks R, Gonnella P, Kuchroo VK, Weiner HL. Peripheral deletion of antigen-reactive T cells in oral tolerance Nature. 377: 257-257. DOI: 10.1038/377257c0 |
0.398 |
|
| 1994 |
Kuchroo VK, Collins M, al-Sabbagh A, Sobel RA, Whitters MJ, Zamvil SS, Dorf ME, Hafler DA, Seidman JG, Weiner HL. T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. The Journal of Experimental Medicine. 179: 1659-64. PMID 8163944 DOI: 10.1084/Jem.179.5.1659 |
0.535 |
|
| 1994 |
Sobel RA, Greer JM, Kuchroo VK. Minireview: autoimmune responses to myelin proteolipid protein. Neurochemical Research. 19: 915-21. PMID 7528354 DOI: 10.1007/Bf00968701 |
0.44 |
|
| 1994 |
Zamvil SS, al-Sabbagh A, Nelson PA, Kaul D, Charles MS, Mitchell DJ, Steinman L, Weiner HL, Kuchroo VK. 'Lupus-prone' mice are susceptible to organ-specific autoimmune disease, experimental allergic encephalomyelitis. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 62: 113-9. PMID 7524528 DOI: 10.1159/000163887 |
0.456 |
|
| 1994 |
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science (New York, N.Y.). 265: 1237-40. PMID 7520605 DOI: 10.1126/Science.7520605 |
0.585 |
|
| 1994 |
Franco A, Southwood S, Arrhenius T, Kuchroo VK, Grey HM, Sette A, Ishioka GY. T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis. European Journal of Immunology. 24: 940-6. PMID 7512036 DOI: 10.1002/Eji.1830240424 |
0.482 |
|
| 1994 |
Chen Y, Kuchroo V, Weiner HL. Myelin basic protein (MBP)-specific TGFβ-secreting CD4+ T-cell clones derived from orally tolerized animals suppress experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 54: 205. DOI: 10.1016/0165-5728(94)90580-0 |
0.479 |
|
| 1994 |
Markovic-Plese S, Fukoara H, Al-Sabbagh A, Sette A, Kuchroo VK, Hafler DA. T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans Journal of Neuroimmunology. 54: 179. DOI: 10.1016/0165-5728(94)90423-5 |
0.459 |
|
| 1994 |
Prabhu Das M, Weiner H, Kuchroo V. Myelin proteolipid protein specific TH2 clones suppress autoimmune encephalomyelitis Journal of Neuroimmunology. 54: 174. DOI: 10.1016/0165-5728(94)90397-2 |
0.351 |
|
| 1993 |
Byrne MC, O'Hara RM, Kuchroo VK, Jayaraman S, Rao A, Dorf ME, Collins M. The role of the cell receptor α in antigen-specific immune suppression Annals of the New York Academy of Sciences. 685: 611-613. PMID 8363270 DOI: 10.1111/J.1749-6632.1993.Tb35924.X |
0.384 |
|
| 1992 |
Dorf ME, Kuchroo VK, Collins M. Suppressor T cells: some answers but more questions. Immunology Today. 13: 241-3. PMID 1388648 DOI: 10.1016/0167-5699(92)90002-O |
0.479 |
|
| 1991 |
Kuchroo VK, Byrne MC, Atsumi Y, Greenfield E, Connolly JB, Whitters MJ, O'Hara RM, Collins M, Dorf ME. T-cell receptor α chain plays a critical role in antigen-specific suppressor cell function Proceedings of the National Academy of Sciences of the United States of America. 88: 8700-8704. PMID 1833764 DOI: 10.1073/Pnas.88.19.8700 |
0.426 |
|
| 1991 |
Kuchroo VK, Sobel RA, Yamamura T, Greenfield E, Dorf ME, Lees MB. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 59: 305-12. PMID 1716908 DOI: 10.1159/000163668 |
0.366 |
|
| 1991 |
Kuchroo VK, Sobel RA, Laning JC, Greenfield E, Ju S, Dorf ME, Lees MB. Heterogeneity of T cell clones specific for an encephalitogenic determinant of myelin proteolipid protein (PLP) Journal of Neuroimmunology. 35: 44. DOI: 10.1016/0165-5728(91)90913-R |
0.458 |
|
| 1991 |
Sobel RA, Kuchroo VK, Wang Y, Dorf ME, Lees MB. Heterogeneous T cell receptor (TcR) Vβs of acute experimental allergic encephalomyelitis (EAE) induced with a myelin proteolipid protein (PLP) peptide and peptide-specific T cell clones Journal of Neuroimmunology. 35: 43. DOI: 10.1016/0165-5728(91)90912-Q |
0.45 |
|
| 1988 |
Dorf ME, Kuchroo VK, Steele JK, O'Hara RM. Understanding suppressor cells: where have we gone wrong? International Reviews of Immunology. 3: 375-92. PMID 2977613 DOI: 10.3109/08830188809051205 |
0.309 |
|
| 1988 |
Kuchroo VK, Steele JK, Billings PR, Selvaraj P, Dorf ME. Expression of CD3-associated antigen-binding receptors on suppressor T cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 9209-13. PMID 2973609 DOI: 10.1073/Pnas.85.23.9209 |
0.422 |
|
| 1987 |
Nelson M, Nelson DS, Kuchroo VK, Spradbrow PB, Jennings PA. Depression of cell-mediated immunity by tumour cell products: induction of resistance by immunotherapeutically active extracts of bovine ocular squamous cell carcinoma. Cancer Immunology, Immunotherapy : Cii. 24: 231-6. PMID 3594486 DOI: 10.1007/Bf00205635 |
0.374 |
|
| 1987 |
Kuchroo VK, Lee VK, Hellström I, Hellström KE, Halliday WJ. Tumor-specific idiotopes on suppressor factors and suppressor cells revealed by monoclonal anti-idiotope antibodies. Cellular Immunology. 104: 105-14. PMID 2948672 DOI: 10.1016/0008-8749(87)90011-6 |
0.34 |
|
| 1985 |
Kuchroo VK, Spradbrow PB. Tumour-associated antigens in bovine ocular squamous cell carcinoma: studies with sera from tumour-bearing animals. Veterinary Immunology and Immunopathology. 9: 23-36. PMID 3895721 DOI: 10.1016/0165-2427(85)90127-8 |
0.395 |
|
| 1985 |
Lee VK, Harriott TG, Kuchroo VK, Halliday WJ, Hellström I, Hellström KE. Monoclonal antiidiotypic antibodies related to a murine oncofetal bladder tumor antigen induce specific cell-mediated tumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 82: 6286-90. PMID 3875859 DOI: 10.1073/Pnas.82.18.6286 |
0.339 |
|
| 1983 |
Kuchroo VK, Jennings PA. Rosetting of bovine T-lymphocytes with autologous and allogeneic red blood cells. Veterinary Immunology and Immunopathology. 3: 461-74. PMID 6983177 DOI: 10.1016/0165-2427(82)90012-5 |
0.465 |
|
| 1982 |
Kuchroo VK, Dutta BM, Gupta RK. Tumour associated antigens in bovine horn cancer. Australian Veterinary Journal. 58: 16-9. PMID 6805457 DOI: 10.1111/J.1751-0813.1982.Tb00571.X |
0.308 |
|
| 1981 |
Kuchroo V, Gupta R, Kalra D. Thymus derived rosette forming cell counts and lymphocyte response to phytohaemagglutinin in animals affected with squamous cell carcinoma of horn Research in Veterinary Science. 31: 144-146. DOI: 10.1016/S0034-5288(18)32483-4 |
0.34 |
|
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