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Ronald J. Vagnozzi, Ph.D. - Publications

Affiliations: 
2013 Cell and Developmental Biology Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Pathology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Baldwin TA, Teuber JP, Kuwabara Y, Subramani A, Lin SJ, Kanisicak O, Vagnozzi RJ, Zhang W, Brody MJ, Molkentin JD. Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Minor Effects on Cardiac Hypertrophy. The Journal of Biological Chemistry. 105426. PMID 37926281 DOI: 10.1016/j.jbc.2023.105426  0.397
2023 Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Gonzalez Teran B, Flanigan W, Kim CK, Lumbao-Conradson K, ... ... Vagnozzi RJ, et al. Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 36711864 DOI: 10.1101/2023.01.06.522937  0.34
2022 McKinsey TA, Foo R, Anene-Nzelu CG, Travers JG, Vagnozzi RJ, Weber N, Thum T. Emerging epigenetic therapies of cardiac fibrosis and remodeling in heart failure: from basic mechanisms to early clinical development. Cardiovascular Research. PMID 36004821 DOI: 10.1093/cvr/cvac142  0.34
2021 Vagnozzi RJ, Kasam RK, Sargent MA, Molkentin JD. Cardiac Cell Therapy Fails to Rejuvenate the Chronically Scarred Rodent Heart. Circulation. 144: 328-331. PMID 34310160 DOI: 10.1161/CIRCULATIONAHA.120.053080  0.341
2020 Vagnozzi RJ, Molkentin JD. Resident macrophages keep mitochondria running in the heart. Cell Research. PMID 33139923 DOI: 10.1038/s41422-020-00427-z  0.304
2020 Vagnozzi RJ, Sargent MA, Molkentin JD. Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion. Circulation. 141: 1037-1039. PMID 32202933 DOI: 10.1161/Circulationaha.119.044686  0.459
2020 Kim AJ, Xu N, Umeyama K, Hulin A, Ponny SR, Vagnozzi RJ, Green EA, Hanson P, McManus BM, Nagashima H, Yutzey KE. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 141: 132-146. PMID 31928435 DOI: 10.1161/Circulationaha.119.042391  0.367
2019 Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen AK, Schwanekamp JA, York AJ, Huang V, Nahrendorf M, Sadayappan S, Molkentin JD. An acute immune response underlies the benefit of cardiac stem-cell therapy. Nature. PMID 31775156 DOI: 10.1038/S41586-019-1802-2  0.495
2019 Vagnozzi RJ, Johansen AKZ, Molkentin JD. CARdiac Immunotherapy: T Cells Engineered to Treat the Fibrotic Heart. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31585799 DOI: 10.1016/J.Ymthe.2019.09.021  0.419
2019 Khalil H, Kanisicak O, Vagnozzi RJ, Johansen AK, Maliken BD, Prasad V, Boyer JG, Brody MJ, Schips T, Kilian KK, Correll RN, Kawasaki K, Nagata K, Molkentin JD. Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart Jci Insight. 4: e128722. PMID 31393098 DOI: 10.1172/Jci.Insight.128722  0.491
2018 Vagnozzi RJ, Sargent MA, Lin SJ, Palpant NJ, Murry CE, Molkentin JD. Genetic Lineage Tracing of Sca-1 Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart. Circulation. PMID 29991486 DOI: 10.1161/Circulationaha.118.035210  0.503
2018 Vagnozzi RJ, Molkentin JD, Houser SR. New Myocyte Formation in the Adult Heart: Endogenous Sources and Therapeutic Implications. Circulation Research. 123: 159-176. PMID 29976685 DOI: 10.1161/Circresaha.118.311208  0.5
2018 Fu X, Khalil H, Kanisicak O, Boyer JG, Vagnozzi RJ, Maliken BD, Sargent MA, Prasad V, Valiente-Alandi I, Blaxall BC, Molkentin JD. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. The Journal of Clinical Investigation. PMID 29664017 DOI: 10.1172/Jci98215  0.436
2017 Kanisicak O, Vagnozzi RJ, Molkentin JD. Identity Crisis for Regenerative Cardiac cKit(+) Cells. Circulation Research. 121: 1130-1132. PMID 29074532 DOI: 10.1161/Circresaha.117.311921  0.467
2017 Khalil H, Kanisicak O, Prasad V, Correll RN, Fu X, Schips T, Vagnozzi RJ, Liu R, Huynh T, Lee SJ, Karch J, Molkentin JD. Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis. The Journal of Clinical Investigation. PMID 28891814 DOI: 10.1172/Jci94753  0.464
2016 Wallner M, Duran JM, Mohsin S, Troupes CD, Vanhoutte D, Borghetti G, Vagnozzi RJ, Gross P, Yu D, Trappanese DM, Kubo H, Toib A, Sharp TE, Harper SC, Volkert MA, et al. Acute Catecholamine Exposure Causes Reversible Myocyte Injury Without Cardiac Regeneration. Circulation Research. PMID 27461939 DOI: 10.1161/Circresaha.116.308687  0.479
2016 Liu R, van Berlo JH, York AJ, Maillet M, Vagnozzi RJ, Molkentin JD. DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling. Circulation Research. PMID 27225478 DOI: 10.1161/Circresaha.115.308238  0.438
2016 Schwanekamp JA, Lorts A, Vagnozzi RJ, Vanhoutte D, Molkentin JD. Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 60-8. PMID 26564821 DOI: 10.1161/Atvbaha.115.306397  0.33
2015 Liu R, Correll RN, Davis J, Vagnozzi RJ, York AJ, Sargent MA, Nairn AC, Molkentin JD. Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations. Journal of Molecular and Cellular Cardiology. 87: 204-13. PMID 26334248 DOI: 10.1016/J.Yjmcc.2015.08.018  0.514
2015 Kwong JQ, Lu X, Correll RN, Schwanekamp JA, Vagnozzi RJ, Sargent MA, York AJ, Zhang J, Bers DM, Molkentin JD. The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart. Cell Reports. PMID 26119742 DOI: 10.1016/J.Celrep.2015.06.002  0.405
2014 Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. Journal of the American College of Cardiology. 64: 696-706. PMID 25125302 DOI: 10.1016/J.Jacc.2014.04.068  0.656
2014 Lal H, Ahmad F, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai EJ, Woodgett J, Gao E, Force T. Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation. 130: 419-30. PMID 24899689 DOI: 10.1161/Circulationaha.113.008364  0.689
2014 van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC, Middleton RC, Marbán E, Molkentin JD. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 509: 337-41. PMID 24805242 DOI: 10.1038/Nature13309  0.454
2014 Duran JM, Makarewich CA, Trappanese D, Gross P, Husain S, Dunn J, Lal H, Sharp TE, Starosta T, Vagnozzi RJ, Berretta RM, Barbe M, Yu D, Gao E, Kubo H, et al. Sorafenib cardiotoxicity increases mortality after myocardial infarction. Circulation Research. 114: 1700-12. PMID 24718482 DOI: 10.1161/Circresaha.114.303200  0.664
2013 Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, et al. MICU1 motifs define mitochondrial calcium uniporter binding and activity. Cell Reports. 5: 1576-88. PMID 24332854 DOI: 10.1016/J.Celrep.2013.11.026  0.546
2013 Vagnozzi RJ, Gatto GJ, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T. Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Science Translational Medicine. 5: 207ra141. PMID 24132636 DOI: 10.1126/Scitranslmed.3006479  0.645
2013 Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y, Ma XL, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3α is a central regulator of age-related pathologies in mice. The Journal of Clinical Investigation. 123: 1821-32. PMID 23549082 DOI: 10.1172/Jci64398  0.594
2012 Vagnozzi RJ, Hoffman NE, Elrod JW, Madesh M, Force T. Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease. Drug Discovery Today. Therapeutic Strategies. 9: e173-e182. PMID 24839450 DOI: 10.1016/J.Ddstr.2013.12.001  0.66
2012 Lal H, Zhou J, Ahmad F, Zaka R, Vagnozzi RJ, Decaul M, Woodgett J, Gao E, Force T. Glycogen synthase kinase-3α limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and death. Circulation. 125: 65-75. PMID 22086876 DOI: 10.1161/Circulationaha.111.050666  0.647
2010 Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. The Journal of Clinical Investigation. 120: 3680-7. PMID 20890047 DOI: 10.1172/Jci43171  0.631
2010 Woulfe KC, Gao E, Lal H, Harris D, Fan Q, Vagnozzi R, DeCaul M, Shang X, Patel S, Woodgett JR, Force T, Zhou J. Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo. Circulation Research. 106: 1635-45. PMID 20360256 DOI: 10.1161/Circresaha.109.211482  0.703
2009 Kerkela R, Woulfe KC, Durand JB, Vagnozzi R, Kramer D, Chu TF, Beahm C, Chen MH, Force T. Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase. Clinical and Translational Science. 2: 15-25. PMID 20376335 DOI: 10.1111/J.1752-8062.2008.00090.X  0.709
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