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Yang Sunny Sun - Publications

Affiliations: 
MGH/Harvard, Boston, MA, United States 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Azzi A, Tao Z, Sun Y, Erb H, Guarino C, Wu X. The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway. Iscience. 26: 107449. PMID 37593458 DOI: 10.1016/j.isci.2023.107449  0.464
2022 Hu L, Sun Y, Liu S, Erb H, Singh A, Mao J, Luo X, Wu X. Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode. Elife. 11. PMID 36398861 DOI: 10.7554/eLife.80210  0.463
2022 Sun Y, Hu L, Tao Z, Jarugumilli GK, Erb H, Singh A, Li Q, Cotton JL, Greninger P, Egan RK, Tony Ip Y, Benes CH, Che J, Mao J, Wu X. Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells. Nature Communications. 13: 6744. PMID 36347861 DOI: 10.1038/s41467-022-34559-0  0.764
2022 Cotton JL, Dang K, Hu L, Sun Y, Singh A, Rajurkar MS, Li Q, Wu X, Mao J. PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis. Cell Reports. 40: 111125. PMID 35858546 DOI: 10.1016/j.celrep.2022.111125  0.437
2022 Gao C, Xiao F, Zhang L, Sun Y, Wang L, Liu X, Sun H, Xie Z, Liang Y, Xu Q, Wang L. inhibition suppresses the growth of lung cancer cells through activation of -mediated ferroptosis. Annals of Translational Medicine. 10: 224. PMID 35280420 DOI: 10.21037/atm-21-6909  0.307
2020 Niu J, Sun Y, Chen B, Zheng B, Jarugumilli GK, Walker SR, Hata AN, Mino-Kenudson M, Frank DA, Wu X. Retraction Note: Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. Nature. PMID 32555452 DOI: 10.1038/S41586-020-2414-6  0.686
2020 Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell. PMID 32259481 DOI: 10.1016/J.Stem.2020.03.002  0.728
2019 Zheng Q, Zhang L, Zhang Q, Pang Z, Sun Y, Yin Z, Lou Z. Discovery of Interacting Proteins of ABA Receptor PYL5 Via Covalent Chemical Capture. Acs Chemical Biology. PMID 31617999 DOI: 10.1021/Acschembio.9B00806  0.331
2019 Niu J, Sun Y, Chen B, Zheng B, Jarugumilli GK, Walker SR, Hata AN, Mino-Kenudson M, Frank DA, Wu X. Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. Nature. PMID 31462771 DOI: 10.1038/S41586-019-1511-X  0.708
2019 Liu Q, Sun Y, Fei Z, Yang Z, Duan K, Zi J, Cui Q, Yu M, Xiong W. Leptin promotes fatty acid oxidation and OXPHOS via the c-Myc/PGC-1 pathway in cancer cells. Acta Biochimica Et Biophysica Sinica. PMID 31187140 DOI: 10.1093/abbs/gmz058  0.322
2018 Chen B, Sun Y, Niu J, Jarugumilli GK, Wu X. Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic Opportunities. Cell Chemical Biology. PMID 29861273 DOI: 10.1016/J.Chembiol.2018.05.003  0.715
2018 Jarugumilli GK, Choi JR, Chan P, Yu M, Sun Y, Chen B, Niu J, DeRan M, Zheng B, Zoeller R, Lin C, Wu X. Chemical probe to identify the cellular targets of the reactive lipid metabolite 2-trans-hexadecenal. Acs Chemical Biology. PMID 29608264 DOI: 10.1021/Acschembio.7B01063  0.651
2018 Xin M, Sun Y, Chen H, Li Q, Dun Y, Guan H, Hao J, Li C. Propylene glycol guluronate sulfate (PGGS) reduces lipid accumulation via AMP-activated kinase activation in palmitate-induced HepG2 cells. International Journal of Biological Macromolecules. PMID 29550423 DOI: 10.1016/j.ijbiomac.2018.03.068  0.307
2017 Berman AY, Manna S, Schwartz NS, Katz YE, Sun Y, Behrmann CA, Yu JJ, Plas DR, Alayev A, Holz MK. ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism. Signal Transduction and Targeted Therapy. 2. PMID 28890840 DOI: 10.1038/Sigtrans.2017.35  0.345
2017 Li C, Liu X, Liu Y, Zhang E, Medepalli K, Masuda K, Li N, Kopras EJ, Kwiatkowski DJ, Borchers MT, Wikenheiser-Brokamp KA, Osterburg A, Mays M, Sun Y, Plas DR, et al. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular Cancer Research : McR. PMID 28710231 DOI: 10.1158/1541-7786.Mcr-17-0077  0.349
2016 Li C, Li N, Liu X, Zhang EY, Sun Y, Masuda K, Li J, Sun J, Morrison T, Li X, Chen Y, Wang J, Karim NA, Zhang Y, Blenis J, et al. Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. Jci Insight. 1: e86629. PMID 27882343 DOI: 10.1172/Jci.Insight.86629  0.362
2016 Goldberg AA, Joung KB, Mansuri A, Kang Y, Echavarria R, Nikolajev L, Sun Y, Yu JJ, Laporte SA, Schwertani A, Kristof AS. Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2. Oncotarget. PMID 27458154 DOI: 10.18632/Oncotarget.10748  0.324
2016 Meng J, Zhang XT, Liu XL, Fan L, Li C, Sun Y, Liang XH, Wang JB, Mei QB, Zhang F, Zhang T. WSTF promotes proliferation and invasion of lung cancer cells by inducing EMT via PI3K/Akt and IL-6/STAT3 signaling pathways. Cellular Signalling. PMID 27449264 DOI: 10.1016/j.cellsig.2016.07.008  0.302
2016 Li J, Shin S, Sun Y, Yoon SO, Li C, Zhang E, Yu J, Zhang J, Blenis J. mTORC1-driven tumor cells are highly sensitive to therapeutic targeting by antagonists of oxidative stress. Cancer Research. PMID 27197195 DOI: 10.1158/0008-5472.Can-15-2629  0.385
2015 He M, Zheng B, Zhang Y, Zhang XH, Wang C, Yang Z, Sun Y, Wu XL, Wen JK. KLF4 mediates the link between TGF-β1-induced gene transcription and H3 acetylation in vascular smooth muscle cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26082460 DOI: 10.1096/fj.15-272658  0.649
2015 Alayev A, Salamon RS, Sun Y, Schwartz NS, Li C, Yu JJ, Holz MK. The Combination of Rapamycin and Resveratrol Causes Apoptosis and Reduces Growth of TSC2-deficient Xenograft Tumors. American Journal of Respiratory Cell and Molecular Biology. PMID 25844891 DOI: 10.1165/Rcmb.2015-0022Oc  0.334
2015 Medvetz D, Sun Y, Li C, Khabibullin D, Balan M, Parkhitko A, Priolo C, Asara JM, Pal S, Yu J, Henske EP. High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting. Molecular Cancer Research : McR. 13: 50-62. PMID 25185584 DOI: 10.1158/1541-7786.Mcr-14-0440  0.361
2015 Li C, Lee P, Sun Y, Zhang E, Gu X, Li J, Xu K, Csibi A, Blenis J, Henske EP, Levy B, Kwiatkowski D, Yu JJ. Abstract B10: Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in tuberous sclerosis complex Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-B10  0.394
2014 Li C, Zhang E, Sun Y, Lee PS, Zhan Y, Guo Y, Osorio JC, Rosas IO, Xu KF, Kwiatkowski DJ, Yu JJ. Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis. Plos One. 9: e104809. PMID 25347447 DOI: 10.1371/Journal.Pone.0104809  0.374
2014 Sun Y, Zhang E, Lao T, Pereira AM, Li C, Xiong L, Morrison T, Haley KJ, Zhou X, Yu JJ. Progesterone and estradiol synergistically promote the lung metastasis of tuberin-deficient cells in a preclinical model of lymphangioleiomyomatosis. Hormones & Cancer. 5: 284-98. PMID 25069840 DOI: 10.1007/S12672-014-0192-Z  0.354
2014 Sun Y, Gallacchi D, Zhang EY, Reynolds SB, Robinson L, Malinowska IA, Chiou TT, Pereira AM, Li C, Kwiatkowski DJ, Lee PS, Yu JJ. Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis. American Journal of Respiratory Cell and Molecular Biology. 51: 738-49. PMID 24874429 DOI: 10.1165/Rcmb.2014-0033Oc  0.339
2014 Li C, Lee PS, Sun Y, Gu X, Zhang E, Guo Y, Wu CL, Auricchio N, Priolo C, Li J, Csibi A, Parkhitko A, Morrison T, Planaguma A, Kazani S, et al. Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. The Journal of Experimental Medicine. 211: 15-28. PMID 24395886 DOI: 10.1084/Jem.20131080  0.36
2014 Alayev A, Sun Y, Snyder RB, Berger SM, Yu JJ, Holz MK. Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells. Cell Cycle (Georgetown, Tex.). 13: 371-82. PMID 24304514 DOI: 10.4161/Cc.27355  0.376
2014 Li C, Lee P, Sun Y, Gu X, Zhang E, Wu C, Parkhitko A, Aurrichio N, Morrison T, Blenis J, Xu K, Henske EP, Levy B, Kwiatkowski D, Yu J. Abstract B09: Aspirin inhibits cyclooxygenase 2-mediated prostaglandin production and tumorigenesisin a preclinical model of tuberous sclerosis complex Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B09  0.366
2013 Li C, Lee P, Gu X, Sun Y, Zhang E, Csibi A, Li J, Priolo C, Guo Y, Wu C, Blenis J, Xu K, Henske EP, Levy B, Kwiatkowski D, et al. Abstract C59: Estradiol and mTORC2 orchestrate to enhance prostaglandin biosynthesis andtumorigenesis in tuberous sclerosis complex Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C59  0.368
2013 Sun Y, Li C, Marks K, Zhang E, Morrison T, Park M, Wang S, Dillon S, Bhasin M, Libermann T, Driggers E, Gerbaudo V, Henske EP, Yu J. Abstract LB-129: Evidence from expression profiling, proteomics, metabolomics and FDG-PET of an estrogen-dependent metabolic switch in tuberin-null cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-129  0.397
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