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Louis Y P Luk - Publications

Affiliations: 
Cardiff University, Cardiff, Wales, United Kingdom 
Area:
Biocatalysis
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Galmés MÀ, Nödling AR, Luk L, Świderek K, Moliner V. Combined Theoretical and Experimental Study to Unravel the Differences in Promiscuous Amidase Activity of Two Nonhomologous Enzymes. Acs Catalysis. 11: 8635-8644. PMID 35875595 DOI: 10.1021/acscatal.1c02150  0.344
2021 Allemann RK, Adresina AS, Luk L. Cryo-kinetics reveal dynamic effects on the chemistry of human dihydrofolate reductase. Chembiochem : a European Journal of Chemical Biology. PMID 33876533 DOI: 10.1002/cbic.202100017  0.407
2019 Scott AF, Cresser-Brown J, Williams TL, Rizkallah PJ, Jin Y, Luk LY, Allemann RK. Crystal Structure and Biophysical Analysis of Furfural Detoxifying Aldehyde Reductase from . Applied and Environmental Microbiology. PMID 31101612 DOI: 10.1128/Aem.00978-19  0.343
2019 Allemann RK, Scott AF, Luk LY, Tuñón I, Moliner V. Heavy enzymes and the rational redesign of protein catalysts. Chembiochem : a European Journal of Chemical Biology. PMID 31016852 DOI: 10.1002/Cbic.201900134  0.408
2018 Allemann RK, Ruiz-Pernia JJ, Luk L, Tunon I, Moliner V, Behiry E. Isotope substitution of promiscuous alcohol dehydrogenase reveals origin of substrate preference in transition state. Angewandte Chemie (International Ed. in English). PMID 29341402 DOI: 10.1002/Anie.201712826  0.425
2017 Loveridge EJ, Hroch L, Hughes RL, Williams T, Davies RL, Angelastro A, Luk LY, Maglia G, Allemann RK. Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima. Biochemistry. PMID 28319664 DOI: 10.1021/Acs.Biochem.6B01268  0.39
2016 Castillo JP, Sánchez-Rodríguez JE, Hyde HC, Zaelzer CA, Aguayo D, Sepúlveda RV, Luk LY, Kent SB, Gonzalez-Nilo FD, Bezanilla F, Latorre R. β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 27217576 DOI: 10.1073/Pnas.1606381113  0.339
2015 Luk LY, Ruiz-Pernía JJ, Adesina AS, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Chemical Ligation and Isotope Labeling to Locate Dynamic Effects during Catalysis by Dihydrofolate Reductase. Angewandte Chemie (International Ed. in English). 54: 9016-20. PMID 26079622 DOI: 10.1002/Anie.201503968  0.402
2015 Luk LY, Loveridge EJ, Allemann RK. Protein motions and dynamic effects in enzyme catalysis. Physical Chemistry Chemical Physics : Pccp. 17: 30817-27. PMID 25854702 DOI: 10.1039/C5Cp00794A  0.424
2014 Luk LY, Ruiz-Pernía JJ, Dawson WM, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Protein isotope effects in dihydrofolate reductase from Geobacillus stearothermophilus show entropic-enthalpic compensatory effects on the rate constant. Journal of the American Chemical Society. 136: 17317-23. PMID 25396728 DOI: 10.1021/Ja5102536  0.436
2014 Behiry EM, Luk LY, Matthews SM, Loveridge EJ, Allemann RK. Role of the occluded conformation in bacterial dihydrofolate reductases. Biochemistry. 53: 4761-8. PMID 25014833 DOI: 10.1021/Bi500507V  0.325
2014 Luk LY, Loveridge EJ, Allemann RK. Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases. Journal of the American Chemical Society. 136: 6862-5. PMID 24779446 DOI: 10.1021/Ja502673H  0.473
2014 Guo J, Luk LY, Loveridge EJ, Allemann RK. Thermal adaptation of dihydrofolate reductase from the moderate thermophile Geobacillus stearothermophilus. Biochemistry. 53: 2855-63. PMID 24730604 DOI: 10.1021/Bi500238Q  0.31
2013 Ruiz-Pernia JJ, Luk LY, García-Meseguer R, Martí S, Loveridge EJ, Tuñón I, Moliner V, Allemann RK. Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society. 135: 18689-96. PMID 24252106 DOI: 10.1021/Ja410519H  0.444
2013 Luk LY, Javier Ruiz-Pernía J, Dawson WM, Roca M, Loveridge EJ, Glowacki DR, Harvey JN, Mulholland AJ, Tuñón I, Moliner V, Allemann RK. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis. Proceedings of the National Academy of Sciences of the United States of America. 110: 16344-9. PMID 24065822 DOI: 10.1073/Pnas.1312437110  0.467
2013 Guo J, Loveridge EJ, Luk LY, Allemann RK. Effect of dimerization on dihydrofolate reductase catalysis. Biochemistry. 52: 3881-7. PMID 23672258 DOI: 10.1021/Bi4005073  0.397
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