| Year |
Citation |
Score |
| 2016 |
David N, Pasceri R, Kitson RR, Pradal A, Moody CJ. Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27346186 DOI: 10.1002/Chem.201601605 |
0.47 |
|
| 2015 |
Xiong R, Zhou W, Siegel D, Kitson RR, Freed CR, Moody CJ, Ross D. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity. Molecular Pharmacology. PMID 26405178 DOI: 10.1124/Mol.115.101451 |
0.449 |
|
| 2015 |
Chang C, Ross D, Siegel D, Moody CJ, Kitson R. Abstract 1732: Effect of 19-substituted benzoquinone ansamycin Hsp90 inhibitors on Hsp90/Cdc37/co-chaperone complexes and casein kinase 2 (CK2) activity Cancer Research. 75: 1732-1732. DOI: 10.1158/1538-7445.Am2015-1732 |
0.485 |
|
| 2014 |
Chang CH, Drechsel DA, Kitson RR, Siegel D, You Q, Backos DS, Ju C, Moody CJ, Ross D. 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. Molecular Pharmacology. 85: 849-57. PMID 24682466 DOI: 10.1124/Mol.113.090654 |
0.546 |
|
| 2014 |
Nawrat CC, Kitson RR, Moody CJ. Toward the total synthesis of hygrocin B and divergolide C: construction of the naphthoquinone-azepinone core. Organic Letters. 16: 1896-9. PMID 24661134 DOI: 10.1021/Ol5003847 |
0.503 |
|
| 2014 |
Dutton BL, Kitson RR, Parry-Morris S, Roe SM, Prodromou C, Moody CJ. Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90. Organic & Biomolecular Chemistry. 12: 1328-40. PMID 24435512 DOI: 10.1039/C3Ob42211A |
0.507 |
|
| 2014 |
Drechsel DA, Chang C, Kitson R, Siegel D, Moody CJ, Ross D. Abstract 1791: 19-Substituted benzoquinone ansamycin Hsp90 inhibitors: Effects on Hsp90 co-chaperones and Hsp90-Hsf1 complexes in cellular systems Cancer Research. 74: 1791-1791. DOI: 10.1158/1538-7445.Am2014-1791 |
0.537 |
|
| 2013 |
Kitson RR, Moody CJ. An improved route to 19-substituted geldanamycins as novel Hsp90 inhibitors--potential therapeutics in cancer and neurodegeneration. Chemical Communications (Cambridge, England). 49: 8441-3. PMID 23770604 DOI: 10.1039/C3Cc43457E |
0.517 |
|
| 2013 |
Kitson RR, Chang CH, Xiong R, Williams HE, Davis AL, Lewis W, Dehn DL, Siegel D, Roe SM, Prodromou C, Ross D, Moody CJ. Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nature Chemistry. 5: 307-14. PMID 23511419 DOI: 10.1038/Nchem.1596 |
0.545 |
|
| 2013 |
Kitson RR, Moody CJ. Learning from nature: advances in geldanamycin- and radicicol-based inhibitors of Hsp90. The Journal of Organic Chemistry. 78: 5117-41. PMID 23496136 DOI: 10.1021/Jo4002849 |
0.521 |
|
| 2012 |
Chang C, Kitson R, Siegel D, Moody CJ, Ross D. Abstract 2769: The development of 19-substituted benzoquinone ansamycins as potential anticancer drugs Cancer Research. 72: 2769-2769. DOI: 10.1158/1538-7445.Am2012-2769 |
0.517 |
|
| 2011 |
Chang C, Kitson R, Reigan P, Siegel D, Moody CJ, Ross D. Abstract B102: 19-Substituted benzoquinone ansamycins: Decreasing the toxicity of the benzoquinone ansamycin class of Hsp90 inhibitors. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B102 |
0.578 |
|
| 2011 |
Kitson RR, McAllister GD, Taylor RJ. Synthesis of yomogin using a telescoped α-methylene-γ-butyrolactone annelation procedure Tetrahedron Letters. 52: 561-564. DOI: 10.1016/J.Tetlet.2010.11.143 |
0.499 |
|
| 2009 |
Kitson RR, Millemaggi A, Taylor RJ. The renaissance of alpha-methylene-gamma-butyrolactones: new synthetic approaches. Angewandte Chemie (International Ed. in English). 48: 9426-51. PMID 19938025 DOI: 10.1002/Anie.200903108 |
0.443 |
|
| 2009 |
Kitson RR, Taylor RJ, Wood JL. A one-pot, base-free annelation approach to alpha-alkylidene-gamma-butyrolactones. Organic Letters. 11: 5338-41. PMID 19860387 DOI: 10.1021/Ol902191D |
0.452 |
|
| 2009 |
Kitson R, Millemaggi A, Taylor R. Die Renaissance der α-Methylen-γ-butyrolactone: neue Syntheseansätze Angewandte Chemie. 121: 9590-9615. DOI: 10.1002/Ange.200903108 |
0.376 |
|
| 2008 |
Edwards MG, Kenworthy MN, Kitson RR, Scott MS, Taylor RJ. The telescoped intramolecular michael/olefination (TIMO) approach to alpha-alkylidene-gamma-butyrolactones: synthesis of (+)-paeonilactone B. Angewandte Chemie (International Ed. in English). 47: 1935-7. PMID 18228235 DOI: 10.1002/Anie.200705329 |
0.582 |
|
| 2008 |
Taylor R, Edwards M, Kenworthy M, Kitson R, Scott M. Synthesis of (+)-Paeonilactone B Synfacts. 2008: 0675-0675. DOI: 10.1055/S-2008-1077860 |
0.561 |
|
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