Year |
Citation |
Score |
2024 |
Xie SC, Wang Y, Morton CJ, Metcalfe RD, Dogovski C, Pasaje CFA, Dunn E, Luth MR, Kumpornsin K, Istvan ES, Park JS, Fairhurst KJ, Ketprasit N, Yeo T, Yildirim O, ... ... Rutledge PJ, et al. Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature Communications. 15: 937. PMID 38297033 DOI: 10.1038/s41467-024-45224-z |
0.506 |
|
2023 |
Tilley L, Xie S, Wang Y, Morton C, Metcalfe R, Dogovski C, Pasaje CF, Dunn E, Luth M, Kumpornsin K, Istvan E, Park J, Fairhurst K, Yeo T, Yildirim O, ... ... Rutledge P, et al. Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Research Square. PMID 37546892 DOI: 10.21203/rs.3.rs-3198291/v1 |
0.506 |
|
2022 |
Ball SR, Adamson JSP, Sullivan MA, Zimmermann MR, Lo V, Sanz-Hernandez M, Jiang X, Kwan AH, McKenzie ADJ, Werry EL, Knowles TPJ, Kassiou M, Meisl G, Todd MH, Rutledge PJ, et al. Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid. Acs Chemical Neuroscience. PMID 36542544 DOI: 10.1021/acschemneuro.2c00498 |
0.469 |
|
2021 |
Counsell AJ, Yu M, Shi M, Jones AT, Batten JM, Turner P, Todd MH, Rutledge PJ. Copper(II) complexes of -propargyl cyclam ligands reveal a range of coordination modes and colours, and unexpected reactivity. Dalton Transactions (Cambridge, England : 2003). PMID 33635937 DOI: 10.1039/d0dt03736b |
0.766 |
|
2020 |
Frei A, Zuegg J, Elliott AG, Baker M, Braese S, Brown C, Chen F, Dowson CG, Dujardin G, Jung N, King AP, Mansour AM, Massi M, Moat J, Mohamed HA, ... ... Rutledge PJ, et al. Correction: Metal complexes as a promising source for new antibiotics. Chemical Science. 11: 4531. PMID 34122912 DOI: 10.1039/d0sc90075c |
0.49 |
|
2020 |
Korsik M, Tse E, Smith DG, Lewis W, Rutledge PJ, Todd MH. Tele-substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3-a]pyrazine-Based Antimalarials. The Journal of Organic Chemistry. PMID 32786609 DOI: 10.1021/Acs.Joc.0C01045 |
0.576 |
|
2020 |
Frei A, Zuegg J, Elliott AG, Baker M, Braese S, Brown C, Chen F, G Dowson C, Dujardin G, Jung N, King AP, Mansour AM, Massi M, Moat J, Mohamed HA, ... ... Rutledge PJ, et al. Metal complexes as a promising source for new antibiotics. Chemical Science. 11: 2627-2639. PMID 32206266 DOI: 10.1039/C9Sc06460E |
0.562 |
|
2020 |
Frei A, Zuegg J, Elliott AG, Baker M, Braese S, Brown C, Chen F, Dowson CG, Dujardin G, Jung N, King AP, Mansour AM, Massi M, Moat J, Mohamed HA, ... ... Rutledge PJ, et al. Correction: Metal complexes as a promising source for new antibiotics Chemical Science. 11: 4531-4531. DOI: 10.1039/D0Sc90075C |
0.537 |
|
2018 |
Guardia A, Baiget J, Cacho M, Pérez A, Ortega-Guerra M, Nxumalo W, Khanye S, Rullas J, Ortega F, Jimenez E, Perez-Herran E, Fraile-Gabaldón MT, Esquivias J, Fernández R, Porras-De Francisco E, ... ... Rutledge PJ, et al. Easy-to-Synthesize Spirocyclic Compounds Possess Remarkable In Vivo Activity Against Mycobacterium Tuberculosis. Journal of Medicinal Chemistry. PMID 30457865 DOI: 10.1021/Acs.Jmedchem.8B01533 |
0.548 |
|
2018 |
Spain M, Wong JK, Nagalingam G, Batten JM, Hortle E, Oehlers S, Jiang XF, Murage HE, Orford JT, Crisologo P, Triccas JA, Rutledge PJ, Todd MH. Anti-Tubercular bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and In Vivo Studies. Journal of Medicinal Chemistry. PMID 29558124 DOI: 10.1021/Acs.Jmedchem.7B01569 |
0.752 |
|
2017 |
Lau YH, Clegg JK, Price JR, Marquart RB, Todd MH, Rutledge PJ. Molecular Switches for any pH: A Systematic Study of the Versatile Coordination Behaviour of Cyclam Scorpionands. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29052259 DOI: 10.1002/Chem.201703488 |
0.591 |
|
2017 |
McNeill L, Brown T, Sami M, Clifton I, Burzlaff N, Claridge T, Adlington R, Baldwin J, Rutledge PJ, Schofield C. Terminally truncated isopenicillin N synthase generates a dithioester product: evidence for a thioaldehyde intermediate and a new mode of reaction for non-heme iron oxidases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28703303 DOI: 10.1002/Chem.201701592 |
0.76 |
|
2017 |
Hossain MA, Canning J, Yu Z, Ast S, Rutledge PJ, Wong JK, Jamalipour A, Crossley MJ. Time-resolved and temperature tuneable measurements of fluorescent intensity using a smartphone fluorimeter. The Analyst. PMID 28474014 DOI: 10.1039/C7An00535K |
0.772 |
|
2017 |
Wong JK, Todd MH, Rutledge PJ. Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing. Molecules (Basel, Switzerland). 22. PMID 28125069 DOI: 10.3390/Molecules22020200 |
0.707 |
|
2017 |
Devi P, Rutledge PJ. Cyclobutanone Analogues of β-Lactam Antibiotics: β-Lactamase Inhibitors with Untapped Potential? Chembiochem : a European Journal of Chemical Biology. 18: 338-351. PMID 27992105 DOI: 10.1002/Cbic.201600529 |
0.586 |
|
2017 |
Wong JK, Proschogo N, Todd MH, Rutledge PJ. Selective Displacement of a Scorpionand Triazole Ligand from Metallocyclam Complexes Visualised with NMR Spectroscopy European Journal of Inorganic Chemistry. 2017: 1075-1086. DOI: 10.1002/Ejic.201601474 |
0.57 |
|
2016 |
Counsell AJ, Jones AT, Todd MH, Rutledge PJ. A direct method for the N-tetraalkylation of azamacrocycles. Beilstein Journal of Organic Chemistry. 12: 2457-2461. PMID 28144313 DOI: 10.3762/Bjoc.12.239 |
0.769 |
|
2016 |
Wong JK, Ast S, Yu M, Flehr R, Counsell AJ, Turner P, Crisologo P, Todd MH, Rutledge PJ. Synthesis and Evaluation of 1,8-Disubstituted-Cyclam/Naphthalimide Conjugates as Probes for Metal Ions. Chemistryopen. 5: 375-85. PMID 27547648 DOI: 10.1002/Open.201600010 |
0.776 |
|
2016 |
Yu M, Nagalingam G, Ellis S, Martinez E, Sintchenko V, Spain M, Rutledge PJ, Todd MH, Triccas JA. Non-toxic metal-cyclam complexes, a new class of compounds with potency against drug-resistant Mycobacterium tuberculosis. Journal of Medicinal Chemistry. PMID 27214150 DOI: 10.1021/Acs.Jmedchem.6B00432 |
0.531 |
|
2015 |
Porter D, Poon BM, Rutledge PJ. Iron complexes of tetramine ligands catalyse allylic hydroxyamination via a nitroso-ene mechanism. Beilstein Journal of Organic Chemistry. 11: 2549-56. PMID 26734101 DOI: 10.3762/Bjoc.11.275 |
0.355 |
|
2015 |
Devi P, Barry SM, Houlihan KM, Murphy MJ, Turner P, Jensen P, Rutledge PJ. Synthesis and structural characterisation of amides from picolinic acid and pyridine-2,6-dicarboxylic acid. Scientific Reports. 5: 9950. PMID 25954918 DOI: 10.1038/Srep09950 |
0.636 |
|
2015 |
Arafat Hossain M, Canning J, Ast S, Cook K, Rutledge PJ, Jamalipour A. Combined "dual" absorption and fluorescence smartphone spectrometers. Optics Letters. 40: 1737-40. PMID 25872061 DOI: 10.1364/Ol.40.001737 |
0.754 |
|
2015 |
Yu M, Wong JK, Tang C, Turner P, Todd MH, Rutledge PJ. Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids. Beilstein Journal of Organic Chemistry. 11: 37-41. PMID 25670990 DOI: 10.3762/Bjoc.11.6 |
0.664 |
|
2015 |
Canning J, Ast S, Hossain MA, Chan H, Rutledge PJ, Jamalipour A. Bend and twist intramolecular charge transfer and emission for selective metal ion sensing Optical Materials Express. 5: 2675. DOI: 10.1364/Ome.5.002675 |
0.761 |
|
2015 |
Hossain MA, Canning J, Cook K, Ast S, Rutledge PJ, Jamalipour A. Absorption and fluorescence spectroscopy on a smartphone Proceedings of Spie - the International Society For Optical Engineering. 9655. DOI: 10.1117/12.2184354 |
0.738 |
|
2015 |
Hossain MA, Ast S, Canning J, Cook K, Rutledge PJ, Jamalipour A. Fluorescent measurements of Zn2+ on a smartphone Proceedings of Spie - the International Society For Optical Engineering. 9655. DOI: 10.1117/12.2184246 |
0.741 |
|
2015 |
Hossain A, Canning J, Ast S, Rutledge PJ, Yen TL, Jamalipour A. Lab-in-a-Phone: Smartphone-Based Portable Fluorometer for pH Measurements of Environmental Water Ieee Sensors Journal. 15: 5095-5102. DOI: 10.1109/Jsen.2014.2361651 |
0.741 |
|
2015 |
Hossain MA, Canning J, Ast S, Rutledge PJ, Jamalipour A. Early warning smartphone diagnostics for water security and analysis using real-time pH mapping Photonic Sensors. 5: 289-297. DOI: 10.1007/S13320-015-0256-X |
0.723 |
|
2015 |
Ast S, Kuke S, Rutledge PJ, Todd MH. Using click chemistry to tune the properties and the fluorescence response mechanism of structurally similar probes for metal ions European Journal of Inorganic Chemistry. 2015: 58-66. DOI: 10.1002/Ejic.201402811 |
0.804 |
|
2014 |
Byrne C, Houlihan KM, Devi P, Jensen P, Rutledge PJ. Bio-inspired nitrile hydration by peptidic ligands based on L-cysteine, L-methionine or L-penicillamine and pyridine-2,6-dicarboxylic acid. Molecules (Basel, Switzerland). 19: 20751-67. PMID 25514220 DOI: 10.3390/Molecules191220751 |
0.66 |
|
2014 |
Ast S, Rutledge PJ, Todd MH. The properties and performance of a pH-responsive functionalised nanoparticle. Faraday Discussions. 175: 171-87. PMID 25483149 DOI: 10.1039/C4Fd00110A |
0.772 |
|
2014 |
Ast S, Rutledge PJ, Todd MH. pH-Responsive quantum dots (RQDs) that combine a fluorescent nanoparticle with a pH-sensitive dye. Physical Chemistry Chemical Physics : Pccp. 16: 25255-7. PMID 25338264 DOI: 10.1039/C4Cp03914A |
0.765 |
|
2014 |
Yu M, Ryan TM, Ellis S, Bush AI, Triccas JA, Rutledge PJ, Todd MH. Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β. Metallomics : Integrated Biometal Science. 6: 1931-40. PMID 25132118 DOI: 10.1039/C4Mt00122B |
0.587 |
|
2014 |
Yu M, Ast S, Yu Q, Lo AT, Flehr R, Todd MH, Rutledge PJ. Incorporating a piperidinyl group in the fluorophore extends the fluorescence lifetime of click-derived cyclam-naphthalimide conjugates. Plos One. 9: e100761. PMID 24983863 DOI: 10.1371/Journal.Pone.0100761 |
0.798 |
|
2014 |
Canning J, Hossain A, Ast S, Yen TL, Rutledge P, Jamalipour A. A smartphone fluorometer – the lab-in-a-phone Sensors. DOI: 10.1364/Sensors.2014.Seth2C.1 |
0.742 |
|
2013 |
Yu M, Lim NH, Ellis S, Nagase H, Triccas JA, Rutledge PJ, Todd MH. Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity. Chemistryopen. 2: 99-105. PMID 24551546 DOI: 10.1002/Open.201300014 |
0.576 |
|
2013 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site Febs Letters. 587: 2705-2709. PMID 23860486 DOI: 10.1016/J.Febslet.2013.07.016 |
0.638 |
|
2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ-(L-α-Aminoadipoyl)-L-homocysteinyl-D-Xaa Characterised by Protein Crystallography Chembiochem. 14: 599-606. PMID 23468426 DOI: 10.1002/Cbic.201200728 |
0.626 |
|
2013 |
Yu M, Yu Q, Rutledge PJ, Todd MH. A fluorescent "allosteric scorpionand" complex visualizes a biological recognition event. Chembiochem : a European Journal of Chemical Biology. 14: 224-9. PMID 23303717 DOI: 10.1002/Cbic.201200637 |
0.72 |
|
2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue Archives of Biochemistry and Biophysics. 530: 48-53. PMID 23262315 DOI: 10.1016/J.Abb.2012.12.012 |
0.628 |
|
2013 |
Dungan VJ, Poon BML, Barrett ES, Rutledge PJ. L-Proline derived mimics of the non-haem iron active site catalyse allylic oxidation in acetonitrile solutions Tetrahedron Letters. 54: 1236-1238. DOI: 10.1016/J.Tetlet.2012.12.095 |
0.333 |
|
2012 |
Barry SM, Mueller-Bunz H, Rutledge PJ. Investigating the oxidation of alkenes by non-heme iron enzyme mimics. Organic & Biomolecular Chemistry. 10: 7372-81. PMID 22858835 DOI: 10.1039/C2Ob25834J |
0.322 |
|
2012 |
Dungan VJ, Wong SM, Barry SM, Rutledge PJ. l-Proline-derived ligands to mimic the ‘2-His-1-carboxylate’ triad of the non-haem iron oxidase active site Tetrahedron. 68: 3231-3236. DOI: 10.1016/J.Tet.2012.02.031 |
0.353 |
|
2012 |
Ast S, Rutledge PJ, Todd MH. Reversing the triazole topology in a cyclam-triazole-dye ligand gives a 10-fold brighter signal response to Zn 2+ in aqueous solution European Journal of Inorganic Chemistry. 5611-5615. DOI: 10.1002/Ejic.201201072 |
0.794 |
|
2011 |
Yu M, Price JR, Jensen P, Lovitt CJ, Shelper T, Duffy S, Windus LC, Avery VM, Rutledge PJ, Todd MH. Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic. Inorganic Chemistry. 50: 12823-35. PMID 22111787 DOI: 10.1021/Ic2020012 |
0.597 |
|
2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with δ-(l-α- aminoadipoyl)-l-cysteinyl-d-methionine reveals thioether coordination to iron Archives of Biochemistry and Biophysics. 516: 103-107. PMID 22001738 DOI: 10.1016/J.Abb.2011.09.014 |
0.645 |
|
2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N Synthase Binds δ-(L-α-Aminoadipoyl)-L-Cysteinyl-D-Thia-allo-Isoleucine through both Sulfur Atoms Chembiochem. 12: 1881-1885. PMID 21678539 DOI: 10.1002/Cbic.201100149 |
0.638 |
|
2011 |
Lo AT, Salam NK, Hibbs DE, Rutledge PJ, Todd MH. Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal. Plos One. 6: e17446. PMID 21573061 DOI: 10.1371/Journal.Pone.0017446 |
0.581 |
|
2011 |
Lau YH, Rutledge PJ, Watkinson M, Todd MH. Chemical sensors that incorporate click-derived triazoles. Chemical Society Reviews. 40: 2848-66. PMID 21380414 DOI: 10.1039/C0Cs00143K |
0.549 |
|
2011 |
Lau YH, Price JR, Todd MH, Rutledge PJ. A click fluorophore sensor that can distinguish Cu(II) and Hg(II) via selective anion-induced demetallation. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 2850-8. PMID 21305620 DOI: 10.1002/Chem.201002477 |
0.595 |
|
2011 |
Hosseini SS, Bhadbhade M, Clarke RJ, Rutledge PJ, Rendina LM. Synthesis, carbohydrate- and DNA-binding studies of cationic 2,2':6',2''-terpyridineplatinum(II) complexes containing N- and S-donor boronic acid ligands. Dalton Transactions (Cambridge, England : 2003). 40: 506-13. PMID 21088793 DOI: 10.1039/C0Dt00892C |
0.343 |
|
2011 |
Bridgeman AJ, Rutledge PJ, Todd MH, Connor R. A treasure hunt for chemistry Journal of Chemical Education. 88: 437-439. DOI: 10.1021/Ed100867M |
0.502 |
|
2011 |
Scully CCG, Lau YH, Jensen P, Rutledge PJ. Synthesis, electrochemistry and metal binding properties of monosubstituted ferrocenoyl peptides with thioether-containing sidechains Journal of Organometallic Chemistry. 696: 715-721. DOI: 10.1016/J.Jorganchem.2010.09.056 |
0.345 |
|
2010 |
Morrison DE, Issa F, Bhadbhade M, Groebler L, Witting PK, Kassiou M, Rutledge PJ, Rendina LM. Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 1305-18. PMID 20694490 DOI: 10.1007/S00775-010-0690-6 |
0.307 |
|
2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase Biochemical and Biophysical Research Communications. 398: 659-664. PMID 20603104 DOI: 10.1016/J.Bbrc.2010.06.129 |
0.628 |
|
2010 |
Dungan VJ, Ortin Y, Mueller-Bunz H, Rutledge PJ. Design and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site. Organic & Biomolecular Chemistry. 8: 1666-73. PMID 20237680 DOI: 10.1039/B921934J |
0.4 |
|
2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase Organic and Biomolecular Chemistry. 8: 122-127. PMID 20024142 DOI: 10.1039/B910170E |
0.659 |
|
2010 |
Scully CC, Rutledge PJ. Synthesis and electrochemical studies of disubstituted ferrocene/dipeptide conjugates with sulfur-containing side chains Tetrahedron. 66: 5653-5659. DOI: 10.1016/J.Tet.2010.05.070 |
0.357 |
|
2009 |
Ge W, Clifton IJ, Howard-Jones AR, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue Chembiochem. 10: 2025-2031. PMID 19598184 DOI: 10.1002/Cbic.200900080 |
0.632 |
|
2008 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: Implications for oxygen binding and a link to nitrile hydratase? Journal of the American Chemical Society. 130: 10096-10102. PMID 18620394 DOI: 10.1021/Ja8005397 |
0.652 |
|
2008 |
Rutledge P, Barry S. cis-Dihydroxylation of Alkenes by a Non-Heme Iron Enzyme Mimic Synlett. 2008: 2172-2174. DOI: 10.1055/S-2008-1078248 |
0.302 |
|
2008 |
Scully CC, Jensen P, Rutledge PJ. Mercury binding by ferrocenoyl peptides with sulfur-containing side chains: Electrochemical, spectroscopic and structural studies Journal of Organometallic Chemistry. 693: 2869-2876. DOI: 10.1016/J.Jorganchem.2008.06.005 |
0.334 |
|
2007 |
Stewart AC, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. A cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthase Chembiochem. 8: 2003-2007. PMID 17907118 DOI: 10.1002/Cbic.200700176 |
0.622 |
|
2007 |
Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762. PMID 17397141 DOI: 10.1021/Bi062314Q |
0.753 |
|
2006 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase Chembiochem. 7: 351-358. PMID 16444759 DOI: 10.1002/Cbic.200500282 |
0.65 |
|
2005 |
Howard-Jones AR, Rutledge PJ, Clifton IJ, Adlington RM, Baldwin JE. Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase Biochemical and Biophysical Research Communications. 336: 702-708. PMID 16143309 DOI: 10.1016/J.Bbrc.2005.08.155 |
0.598 |
|
2005 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Rutledge PJ, Schofield CJ. Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine. Biochemistry. 44: 6619-28. PMID 15850395 DOI: 10.1021/Bi047478Q |
0.593 |
|
2005 |
Krall JA, Rutledge PJ, Baldwin JE. Design and synthesis of an isopenicillin N synthase mimic Tetrahedron. 61: 137-143. DOI: 10.1016/J.Tet.2004.10.041 |
0.521 |
|
2004 |
Grummitt AR, Rutledge PJ, Clifton IJ, Baldwin JE. Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase. The Biochemical Journal. 382: 659-66. PMID 15175003 DOI: 10.1042/Bj20040529 |
0.488 |
|
2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60. PMID 12926272 DOI: 10.1039/B212270G |
0.794 |
|
2003 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Schofield CJ, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate. The Biochemical Journal. 372: 687-93. PMID 12622704 DOI: 10.1042/Bj20021627 |
0.584 |
|
2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460. DOI: 10.1039/b212270g |
0.775 |
|
2003 |
Ferguson AC, Adlington RM, Martyres DH, Rutledge PJ, Cowley A, Baldwin JE. Total synthesis of a novel 2-thiabicyclo[3.2.0]heptan-6-one analogue of penicillin N Tetrahedron. 59: 8233-8243. DOI: 10.1016/J.Tet.2003.08.004 |
0.573 |
|
2002 |
Rutledge PJ, Burzlaff NI, Elkins JM, Pickford M, Baldwin JE, Roach PL. A device for the high-pressure oxygenation of protein crystals. Analytical Biochemistry. 308: 265-8. PMID 12419338 DOI: 10.1016/S0003-2697(02)00246-4 |
0.745 |
|
2001 |
Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. Chemistry & Biology. 8: 1231-7. PMID 11755401 DOI: 10.1016/S1074-5521(01)00090-4 |
0.792 |
|
2001 |
Hamilton CS, Yasuhara A, Baldwin JE, Lloyd MD, Rutledge PJ. Contrasting fates for 6-α-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS) Bioorganic and Medicinal Chemistry Letters. 11: 2511-2514. PMID 11549458 DOI: 10.1016/S0960-894X(01)00470-X |
0.43 |
|
1999 |
Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. The reaction cycle of isopenicillin N synthase observed by X-ray diffraction. Nature. 401: 721-4. PMID 10537113 DOI: 10.1038/44400 |
0.738 |
|
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