| Year |
Citation |
Score |
| 2024 |
Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, ... ... Gao G, et al. A Comprehensive Atlas of AAV Tropism in the Mouse. Biorxiv : the Preprint Server For Biology. PMID 39314496 DOI: 10.1101/2024.09.10.612279 |
0.379 |
|
| 2024 |
Du A, Yang K, Zhou X, Ren L, Liu N, Zhou C, Liang J, Yan N, Gao G, Wang D. Systemic gene therapy corrects neurological phenotype in a mouse model of NGLY1 deficiency. Jci Insight. PMID 39137042 DOI: 10.1172/jci.insight.183189 |
0.407 |
|
| 2024 |
Wang J, Gao G, Wang D. Developing AAV-delivered nonsense suppressor tRNAs for neurological disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 21: e00391. PMID 38959711 DOI: 10.1016/j.neurot.2024.e00391 |
0.35 |
|
| 2024 |
Liang SQ, Navia A, Ramseier M, Zhou X, Martinez ML, Lee CC, Zhou C, Wu J, Xie J, Su Q, Wang D, Flotte TR, Anderson DG, Tarantal AF, Shalek A, ... Gao G, et al. AAV5 delivery of CRISPR/Cas9 mediates genome editing in the lungs of young rhesus monkeys. Human Gene Therapy. PMID 38767512 DOI: 10.1089/hum.2024.035 |
0.314 |
|
| 2024 |
Wang JH, Gessler DJ, Zhan W, Gallagher TL, Gao G. Adeno-associated virus as a delivery vector for gene therapy of human diseases. Signal Transduction and Targeted Therapy. 9: 78. PMID 38565561 DOI: 10.1038/s41392-024-01780-w |
0.336 |
|
| 2024 |
Liu H, Zhang Y, Yip M, Ren L, Liang J, Chen X, Liu N, Du A, Wang J, Chang H, Oh H, Zhou C, Xing R, Xu M, Guo P, ... ... Gao G, et al. Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection. Molecular Therapy. Methods & Clinical Development. 32: 101230. PMID 38558570 DOI: 10.1016/j.omtm.2024.101230 |
0.364 |
|
| 2024 |
Xie Q, Chen X, Ma H, Zhu Y, Ma Y, Jalinous L, Cox GF, Weaver F, Yang J, Kennedy Z, Gruntman A, Du A, Su Q, He R, Tai PW, ... Gao G, et al. Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. Embo Molecular Medicine. PMID 38413838 DOI: 10.1038/s44321-024-00037-x |
0.353 |
|
| 2023 |
Chang H, Du A, Jiang J, Ren L, Liu N, Zhou X, Liang J, Gao G, Wang D. Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice. Molecular Therapy. Methods & Clinical Development. 31: 101129. PMID 37886602 DOI: 10.1016/j.omtm.2023.101129 |
0.404 |
|
| 2023 |
Yang YS, Lin C, Ma H, Xie J, Kaplan FS, Gao G, Shim JH. AAV-Mediated Targeting of the Activin A-ACVR1 Signaling in Fibrodysplasia Ossificans Progressiva. Biomolecules. 13. PMID 37759764 DOI: 10.3390/biom13091364 |
0.31 |
|
| 2023 |
Corti M, Byrne BJ, Gessler DJ, Thompson G, Norman S, Lammers J, Coleman KE, Liberati C, Elder ME, Escolar ML, Tuna IS, Mesaros C, Kleiner GI, Barbouth DS, Gray-Edwards HL, ... ... Gao G, et al. Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation. Molecular Therapy. Methods & Clinical Development. 30: 303-314. PMID 37601414 DOI: 10.1016/j.omtm.2023.06.001 |
0.306 |
|
| 2023 |
Yip M, Chen J, Zhi Y, Tran NT, Namkung S, Pastor E, Gao G, Tai PWL. Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing. Viruses. 15. PMID 37376529 DOI: 10.3390/v15061228 |
0.36 |
|
| 2023 |
Yang H, Brown R, Wang D, Strauss KA, Gao G. Rescue of GM3 synthase deficiency by spatially controlled rAAV-mediated ST3GAL5 delivery. Jci Insight. PMID 37014712 DOI: 10.1172/jci.insight.168688 |
0.384 |
|
| 2022 |
Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong J, Chun H, Shore EM, Kaplan FS, Gao G, Shim JH. Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nature Communications. 13: 6175. PMID 36258013 DOI: 10.1038/s41467-022-33956-9 |
0.309 |
|
| 2022 |
Zhang H, Bamidele N, Liu P, Ojelabi O, Gao XD, Rodriguez T, Cheng H, Kelly K, Watts JK, Xie J, Gao G, Wolfe SA, Xue W, Sontheimer EJ. Adenine Base Editing with a Single Adeno-Associated Virus Vector. Gen Biotechnology. 1: 285-299. PMID 35811581 DOI: 10.1089/genbio.2022.0015 |
0.334 |
|
| 2022 |
Sabatino DE, Bushman CFD, Chandler RJ, Crystal RG, Davidson BL, Dolmetsch R, Eggan KC, Gao G, Gil-Farina I, Kay MA, McCarty DM, Montini E, Ndu A, Yuan J. Evaluating the State of the Science for Adeno-Associated Virus (AAV) Integration:An Integrated Perspective. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35690906 DOI: 10.1016/j.ymthe.2022.06.004 |
0.313 |
|
| 2022 |
Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J, Jiang Z, Kucukural A, Shaffer SA, Gao G, Wang D. AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature. 604: 343-348. PMID 35322228 DOI: 10.1038/s41586-022-04533-3 |
0.392 |
|
| 2022 |
Muhuri M, Levy DI, Schulz M, McCarty D, Gao G. Durability of transgene expression after rAAV gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35283274 DOI: 10.1016/j.ymthe.2022.03.004 |
0.332 |
|
| 2021 |
Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, ... ... Gao G, et al. Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. Nature Communications. 12: 6267. PMID 34725353 DOI: 10.1038/s41467-021-26518-y |
0.387 |
|
| 2021 |
Kumar SRP, Xie J, Hu S, Ko J, Huang Q, Brown HC, Srivastava A, Markusic DM, Doering CB, Spencer HT, Srivastava A, Gao G, Herzog RW. Coagulation factor IX gene transfer to non-human primates using engineered AAV3 capsid and hepatic optimized expression cassette. Molecular Therapy. Methods & Clinical Development. 23: 98-107. PMID 34631930 DOI: 10.1016/j.omtm.2021.08.001 |
0.371 |
|
| 2021 |
Yang H, Brown RH, Wang D, Strauss KA, Gao G. AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies. Trends in Molecular Medicine. PMID 33714697 DOI: 10.1016/j.molmed.2021.02.004 |
0.34 |
|
| 2021 |
Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, ... ... Gao G, et al. Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Science Translational Medicine. 13. PMID 33568518 DOI: 10.1126/scitranslmed.abd3438 |
0.32 |
|
| 2021 |
Bulcha JT, Wang Y, Ma H, Tai PWL, Gao G. Viral vector platforms within the gene therapy landscape. Signal Transduction and Targeted Therapy. 6: 53. PMID 33558455 DOI: 10.1038/s41392-021-00487-6 |
0.306 |
|
| 2020 |
Tang Q, Keeler AM, Zhang S, Su Q, Lyu Z, Cheng Y, Gao G, Flotte TR. Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus. Bioresearch Open Access. 9: 219-228. PMID 33117614 DOI: 10.1089/biores.2020.0031 |
0.385 |
|
| 2020 |
Tran NT, Heiner C, Weber K, Weiand M, Wilmot D, Xie J, Wang D, Brown A, Manokaran S, Su Q, Zapp ML, Gao G, Tai PWL. AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity. Molecular Therapy. Methods & Clinical Development. 18: 639-651. PMID 32775498 DOI: 10.1016/J.Omtm.2020.07.007 |
0.466 |
|
| 2020 |
Su Q, Sena-Esteves M, Gao G. Analysis of Recombinant Adeno-Associated Virus (rAAV) Purity Using Silver-Stained SDS-PAGE. Cold Spring Harbor Protocols. 2020: pdb.prot095679. PMID 32747582 DOI: 10.1101/Pdb.Prot095679 |
0.336 |
|
| 2020 |
Su Q, Sena-Esteves M, Gao G. Purification of Recombinant Adeno-Associated Viruses (rAAVs) by Cesium Chloride Gradient Sedimentation. Cold Spring Harbor Protocols. 2020: pdb.prot095604. PMID 32747580 DOI: 10.1101/Pdb.Prot095604 |
0.326 |
|
| 2020 |
Hsu HL, Brown A, Loveland AB, Lotun A, Xu M, Luo L, Xu G, Li J, Ren L, Su Q, Gessler DJ, Wei Y, Tai PWL, Korostelev AA, Gao G. Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties. Nature Communications. 11: 3279. PMID 32606306 DOI: 10.1038/S41467-020-17047-1 |
0.699 |
|
| 2020 |
Sena-Esteves M, Gao G. Introducing Genes into Mammalian Cells: Viral Vectors. Cold Spring Harbor Protocols. PMID 32457039 DOI: 10.1101/Pdb.Top095513 |
0.441 |
|
| 2020 |
Yang YS, Xie J, Chaugule S, Wang D, Kim JM, Kim J, Tai PWL, Seo SK, Gravallese E, Gao G, Shim JH. Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy. Molecular Therapy. Methods & Clinical Development. 17: 922-935. PMID 32405514 DOI: 10.1016/J.Omtm.2020.04.010 |
0.334 |
|
| 2020 |
Lock M, Wilson J, Sena-Esteves M, Gao G. Sensitive Determination of Infectious Titer of Recombinant Adeno-Associated Viruses (rAAVs) Using TCID End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2020: pdb.prot095653. PMID 32358050 DOI: 10.1101/Pdb.Prot095653 |
0.519 |
|
| 2020 |
Su Q, Sena-Esteves M, Gao G. Titration of Recombinant Adeno-Associated Virus (rAAV) Genome Copy Number Using Real-Time Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2020: pdb.prot095646. PMID 32358049 DOI: 10.1101/Pdb.Prot095646 |
0.354 |
|
| 2020 |
Martinez-Navio JM, Fuchs SP, Mendes DE, Rakasz EG, Gao G, Lifson JD, Desrosiers RC. Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV. Frontiers in Immunology. 11: 449. PMID 32256496 DOI: 10.3389/Fimmu.2020.00449 |
0.338 |
|
| 2020 |
Wang D, Zhang F, Gao G. CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors. Cell. 181: 136-150. PMID 32243786 DOI: 10.1016/J.Cell.2020.03.023 |
0.441 |
|
| 2020 |
Sena-Esteves M, Gao G. Enrichment of Fully Packaged Virions in Column-Purified Recombinant Adeno-Associated Virus (rAAV) Preparations by Iodixanol Gradient Centrifugation Followed by Anion-Exchange Column Chromatography. Cold Spring Harbor Protocols. 2020: pdb.prot095638. PMID 32015003 DOI: 10.1101/Pdb.Prot095638 |
0.321 |
|
| 2020 |
Sena-Esteves M, Gao G. Purification of Recombinant Adeno-Associated Viruses (rAAVs) by Iodixanol Gradient Centrifugation. Cold Spring Harbor Protocols. 2020: pdb.prot095612. PMID 32015002 DOI: 10.1101/Pdb.Prot095612 |
0.424 |
|
| 2020 |
Su Q, Sena-Esteves M, Gao G. Production of Recombinant Adeno-Associated Viruses (rAAVs) by Transient Transfection. Cold Spring Harbor Protocols. 2020: pdb.prot095596. PMID 32015001 DOI: 10.1101/Pdb.Prot095596 |
0.383 |
|
| 2020 |
Flotte TR, Gao G. 2020: Gene Therapy Enters Its Fourth Decade. Human Gene Therapy. 31: 2-3. PMID 31967921 DOI: 10.1089/Hum.2019.29101.Trf |
0.354 |
|
| 2020 |
Fuchs SP, Martinez-Navio JM, Rakasz EG, Gao G, Desrosiers RC. Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys. Molecular Therapy. Methods & Clinical Development. 16: 94-102. PMID 31890736 DOI: 10.1016/J.Omtm.2019.11.010 |
0.405 |
|
| 2019 |
Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C, Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, ... Gao G, et al. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31843447 DOI: 10.1016/J.Ymthe.2019.11.018 |
0.386 |
|
| 2019 |
Mietzsch M, Barnes C, Hull JA, Chipman P, Xie J, Bhattacharya N, Sousa D, McKenna R, Gao G, Agbandje-McKenna M. Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8. Journal of Virology. PMID 31826994 DOI: 10.1128/Jvi.01769-19 |
0.419 |
|
| 2019 |
Lock M, Alvira M, Wilson J, Sena-Esteves M, Gao G. Detection Assay for Replication-Competent Adenovirus by Concentration Passage and Real-Time Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095588. PMID 31792138 DOI: 10.1101/Pdb.Prot095588 |
0.49 |
|
| 2019 |
Su Q, Sena-Esteves M, Gao G. Characterization of the Purified Recombinant Adenovirus for Viral Genome Structure by Restriction Enzyme Digestions. Cold Spring Harbor Protocols. 2019: pdb.prot095554. PMID 31792137 DOI: 10.1101/Pdb.Prot095554 |
0.334 |
|
| 2019 |
Wang D, Niu Y, Ren L, Kang Y, Tai PWL, Si C, Mendonca CA, Ma H, Gao G, Ji W. Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno-Associated Virus. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1900440. PMID 31728271 DOI: 10.1002/Advs.201900440 |
0.473 |
|
| 2019 |
Rashnonejad A, Amini Chermahini G, Gündüz C, Onay H, Aykut A, Durmaz B, Baka M, Su Q, Gao G, Özkınay F. Fetal Gene Therapy Using a Single Injection of Recombinant AAV9 Rescued SMA Phenotype in Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31543414 DOI: 10.1016/J.Ymthe.2019.08.017 |
0.436 |
|
| 2019 |
Lock M, Korn M, Wilson J, Sena-Esteves M, Gao G. Preparation of a DNA Standard for Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095570. PMID 31371468 DOI: 10.1101/Pdb.Prot095570 |
0.349 |
|
| 2019 |
Lock M, Korn M, Wilson J, Sena-Esteves M, Gao G. Measuring the Infectious Titer of Recombinant Adenovirus Using Tissue Culture Infection Dose 50% (TCID) End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095562. PMID 31371467 DOI: 10.1101/Pdb.Prot095562 |
0.436 |
|
| 2019 |
Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, et al. AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges. Science Translational Medicine. 11. PMID 31341061 DOI: 10.1126/Scitranslmed.Aau5409 |
0.367 |
|
| 2019 |
Yang YS, Xie J, Wang D, Kim JM, Tai PWL, Gravallese E, Gao G, Shim JH. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nature Communications. 10: 2958. PMID 31273195 DOI: 10.1038/S41467-019-10809-6 |
0.358 |
|
| 2019 |
Saatcioglu HD, Kano M, Horn H, Zhang L, Samore W, Nagykery N, Meinsohn MC, Hyun M, Suliman R, Poulo J, Hsu J, Sacha C, Wang D, Gao G, Lage K, et al. Single-cell sequencing of neonatal uterus reveals an endometrial progenitor indispensable for fertility. Elife. 8. PMID 31232694 DOI: 10.7554/Elife.46349.001 |
0.353 |
|
| 2019 |
Xiao Y, Muhuri M, Li S, Qin W, Xu G, Luo L, Li J, Letizia AJ, Wang SK, Chan YK, Wang C, Fuchs SP, Wang D, Su Q, Nahid MA, ... ... Gao G, et al. Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity. Jci Insight. 5. PMID 31112525 DOI: 10.1172/Jci.Insight.99052 |
0.458 |
|
| 2019 |
Xu M, Li J, Xie J, He R, Su Q, Gao G, Tai PWL. High-throughput quantification of in vivo AAV transduction with barcoded non-coding RNAs. Human Gene Therapy. PMID 31072208 DOI: 10.1089/Hum.2018.253 |
0.676 |
|
| 2019 |
Su Q, Sena-Esteves M, Gao G. Purification of the Recombinant Adenovirus by Cesium Chloride Gradient Centrifugation. Cold Spring Harbor Protocols. 2019: pdb.prot095547. PMID 31043560 DOI: 10.1101/Pdb.Prot095547 |
0.345 |
|
| 2019 |
Su Q, Sena-Esteves M, Gao G. Release of the Cloned Recombinant Adenovirus Genome for Rescue and Expansion. Cold Spring Harbor Protocols. 2019: pdb.prot095539. PMID 31043559 DOI: 10.1101/Pdb.Prot095539 |
0.365 |
|
| 2019 |
Zhou X, Sena-Esteves M, Gao G. Construction of Recombinant Adenovirus Genomes by Direct Cloning. Cold Spring Harbor Protocols. 2019: pdb.prot095521. PMID 31043558 DOI: 10.1101/Pdb.Prot095521 |
0.366 |
|
| 2019 |
Martinez-Navio JM, Fuchs SP, Pantry SN, Lauer WA, Duggan NN, Keele BF, Rakasz EG, Gao G, Lifson JD, Desrosiers RC. Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression. Immunity. PMID 30850342 DOI: 10.1016/J.Immuni.2019.02.005 |
0.342 |
|
| 2019 |
Gessler DJ, Tai PWL, Li J, Gao G. Intravenous Infusion of AAV for Widespread Gene Delivery to the Nervous System. Methods in Molecular Biology (Clifton, N.J.). 1950: 143-163. PMID 30783972 DOI: 10.1007/978-1-4939-9139-6_8 |
0.377 |
|
| 2019 |
Sanmiguel J, Gao G, Vandenberghe LH. Quantitative and Digital Droplet-Based AAV Genome Titration. Methods in Molecular Biology (Clifton, N.J.). 1950: 51-83. PMID 30783968 DOI: 10.1007/978-1-4939-9139-6_4 |
0.412 |
|
| 2019 |
Wang D, Tai PWL, Gao G. Adeno-associated virus vector as a platform for gene therapy delivery. Nature Reviews. Drug Discovery. PMID 30710128 DOI: 10.1038/S41573-019-0012-9 |
0.516 |
|
| 2019 |
Saatcioglu HD, Kano M, Horn H, Zhang L, Samore W, Nagykery N, Meinsohn M, Hyun M, Suliman R, Poulo J, Hsu J, Sacha C, Wang D, Gao G, Lage K, et al. Author response: Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility Elife. DOI: 10.7554/Elife.46349.036 |
0.326 |
|
| 2018 |
Luo X, Zhang D, Xie J, Su Q, He X, Bai R, Gao G, Pan W. Promotes Schistosomiasis Hepatic Fibrosis in Mice by Suppressing . Molecular Therapy. Methods & Clinical Development. 11: 73-82. PMID 30406154 DOI: 10.1016/J.Omtm.2018.10.002 |
0.335 |
|
| 2018 |
Wang D, Zhong L, Li M, Li J, Tran K, Ren L, He R, Xie J, Moser RP, Fraser C, Kuchel T, Sena-Esteves M, Flotte TR, Aronin N, Gao G. Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer. Molecular Therapy. Methods & Clinical Development. 11: 65-72. PMID 30397628 DOI: 10.1016/J.Omtm.2018.09.003 |
0.514 |
|
| 2018 |
Gong Y, Berenson A, Laheji F, Gao G, Wang D, Ng C, Volak A, Kok R, Kreouzis V, Dijkstra I, Kemp S, Maguire CA, Eichler F. Intrathecal Adeno-Associated Virus Vector-mediated Gene Delivery for Adrenomyeloneuropathy. Human Gene Therapy. PMID 30358470 DOI: 10.1089/Hum.2018.079 |
0.463 |
|
| 2018 |
Mondo E, Moser R, Gao G, Mueller C, Sena-Esteves M, Sapp E, Pfister E, O'Connell D, Takle K, Erger KE, Liu W, Conlon TJ, DiFiglia M, Gounis MJ, Aronin N. Selective Neuronal Uptake and Distribution of AAVrh8, AAV9, and AAVrh10 in Sheep After Intra-Striatal Administration. Journal of Huntington's Disease. PMID 30320596 DOI: 10.3233/Jhd-180302 |
0.415 |
|
| 2018 |
Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G. Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nature Biotechnology. PMID 30102296 DOI: 10.1038/Nbt.4219 |
0.352 |
|
| 2018 |
Liang X, Liu L, Wei YQ, Gao G, Wei X. Toxicity and Efficacy of Nanoparticle-Mediated Gene Therapy in Clinical Study. Human Gene Therapy. PMID 29893153 DOI: 10.1089/Hum.2018.069 |
0.4 |
|
| 2018 |
Xiao W, Gao G, Ling C, Herzog RW, Xiao X, Samulski RJ. Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. Nature Medicine. PMID 29867233 DOI: 10.1038/S41591-018-0062-2 |
0.346 |
|
| 2018 |
Wang D, Li S, Gessler DJ, Xie J, Zhong L, Li J, Tran K, Van Vliet K, Ren L, Su Q, He R, Goetzmann JE, Flotte TR, Agbandje-McKenna M, Gao G. A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates. Molecular Therapy. Methods & Clinical Development. 9: 234-246. PMID 29766031 DOI: 10.1016/J.Omtm.2018.03.004 |
0.521 |
|
| 2018 |
Tai PWL, Xie J, Fong K, Seetin M, Heiner C, Su Q, Weiand M, Wilmot D, Zapp ML, Gao G. Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras. Molecular Therapy. Methods & Clinical Development. 9: 130-141. PMID 29766023 DOI: 10.1016/J.Omtm.2018.02.002 |
0.367 |
|
| 2018 |
Sena-Esteves M, Gao G. Monitoring Lentivirus Vector Stocks for Replication-Competent Viruses. Cold Spring Harbor Protocols. 2018: pdb.prot095703. PMID 29610364 DOI: 10.1101/Pdb.Prot095703 |
0.354 |
|
| 2018 |
Sena-Esteves M, Gao G. Titration of Lentivirus Vectors. Cold Spring Harbor Protocols. 2018: pdb.prot095695. PMID 29610363 DOI: 10.1101/Pdb.Prot095695 |
0.388 |
|
| 2018 |
Sena-Esteves M, Gao G. Production of High-Titer Retrovirus and Lentivirus Vectors. Cold Spring Harbor Protocols. 2018: pdb.prot095687. PMID 29610362 DOI: 10.1101/Pdb.Prot095687 |
0.393 |
|
| 2018 |
Song CQ, Wang D, Jiang T, O'Connor K, Tang Q, Cai L, Li X, Weng Z, Yin H, Gao G, Mueller C, Flotte TR, Xue W. In vivo genome editing partially restores alpha1-antitrypsin in a murine model of AAT deficiency. Human Gene Therapy. PMID 29597895 DOI: 10.1089/Hum.2017.225 |
0.437 |
|
| 2018 |
Wang D, Li J, Tran K, Burt DR, Zhong L, Gao G. Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space. Human Gene Therapy Methods. PMID 29596011 DOI: 10.1089/Hgtb.2017.250 |
0.435 |
|
| 2018 |
He X, Xie J, Wang Y, Fan X, Su Q, Sun Y, Lei N, Zhang D, Gao G, Pan W. Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33. Plos Pathogens. 14: e1006957. PMID 29554131 DOI: 10.1371/Journal.Ppat.1006957 |
0.305 |
|
| 2018 |
Yoon Y, Wang D, Tai PWL, Riley J, Gao G, Rivera-Pérez JA. Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses. Nature Communications. 9: 412. PMID 29379011 DOI: 10.1038/S41467-017-02706-7 |
0.433 |
|
| 2018 |
Luo L, Yang Y, Du T, Kang T, Xiong M, Cheng H, Liu Y, Wu Y, Li Y, Chen Y, Zhang Q, Liu X, Wei X, Mi P, She Z, ... Gao G, et al. Cancer Therapy: Targeted Nanoparticle-Mediated Gene Therapy Mimics Oncolytic Virus for Effective Melanoma Treatment (Adv. Funct. Mater. 29/2018) Advanced Functional Materials. 28: 1870197. DOI: 10.1002/Adfm.201870197 |
0.351 |
|
| 2018 |
Luo L, Yang Y, Du T, Kang T, Xiong M, Cheng H, Liu Y, Wu Y, Li Y, Chen Y, Zhang Q, Liu X, Wei X, Mi P, She Z, ... Gao G, et al. Targeted Nanoparticle-Mediated Gene Therapy Mimics Oncolytic Virus for Effective Melanoma Treatment Advanced Functional Materials. 28: 1800173. DOI: 10.1002/Adfm.201800173 |
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| 2017 |
Pfister E, Dinardo N, Mondo E, Borel F, Conroy F, Fraser C, Gernoux G, Han X, Hu D, Johnson E, Kennington L, Liu P, Reid S, Sapp E, Vodicka P, ... ... Gao G, et al. Artificial miRNAs reduce human mutant Huntingtin throughout the striatum in a transgenic sheep model of Huntington's disease. Human Gene Therapy. PMID 29207890 DOI: 10.1089/Hum.2017.199 |
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| 2017 |
Tao Y, Huang M, Shu Y, Ruprecht A, Wang H, Tang Y, Vandenberghe LH, Wang Q, Gao G, Kong WJ, Chen ZY. Delivery of Adeno-Associated Viral Vectors in Adult Mammalian Inner Ear Cell Subtypes without Auditory Dysfunction. Human Gene Therapy. PMID 29130354 DOI: 10.1089/Hum.2017.120 |
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| 2017 |
Li D, Liu C, Yang C, Wang D, Wu D, Qi Y, Su Q, Gao G, Xu Z, Guo Y. Slow intrathecal injection of rAAVrh10 enhances its transduction of spinal cord and therapeutic efficacy in a mutant SOD1 model of ALS. Neuroscience. PMID 29024785 DOI: 10.1016/J.Neuroscience.2017.10.001 |
0.427 |
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| 2017 |
Magnani DM, Ricciardi MJ, Bailey VK, Gutman MJ, Pedreño-Lopez N, Silveira CGT, Maxwell HS, Domingues A, Gonzalez-Nieto L, Su Q, Newman RM, Pack M, Martins MA, Martinez-Navio JM, Fuchs SP, ... ... Gao G, et al. Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28750738 DOI: 10.1016/J.Ymthe.2017.06.020 |
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| 2017 |
Guggino W, Benson J, Seagrave J, Yan Z, Engelhardt JF, Gao G, Conlon TJ, Cebotaru L. A PRECLINICAL STUDY IN RHESUS MACAQUES FOR CYSTIC FIBROSIS TO ASSESS GENE TRANSFER AND TRANSDUCTION BY AAV1 AND AAV5 WITH A DUAL-LUCIFERASE REPORTER SYSTEM. Human Gene Therapy. Clinical Development. PMID 28726496 DOI: 10.1089/Humc.2017.067 |
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| 2017 |
Zhang W, Li L, Su Q, Gao G, Khanna H. Gene therapy using a miniCEP290 fragment delays photoreceptor degeneration in a mouse model of Leber congenital amaurosis (LCA). Human Gene Therapy. PMID 28679290 DOI: 10.1089/Hum.2017.049 |
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| 2017 |
Petit L, Ma S, Cheng SY, Gao G, Punzo C. Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection. Human Gene Therapy. PMID 28510482 DOI: 10.1089/Hum.2017.020 |
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| 2017 |
Ai J, Ibraheim R, Tai PWL, Gao G. A Scalable and Accurate Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate. Human Gene Therapy Methods. PMID 28488944 DOI: 10.1089/Hgtb.2016.173 |
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| 2017 |
Xie J, Mao Q, Tai PWL, He R, Ai J, Su Q, Zhu Y, Ma H, Li J, Gong S, Wang D, Gao Z, Li M, Zhong L, Zhou H, ... Gao G, et al. Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28462820 DOI: 10.1016/J.Ymthe.2017.03.028 |
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| 2017 |
Gessler DJ, Li D, Xu H, Su Q, Sanmiguel J, Tuncer S, Moore C, King J, Matalon R, Gao G. Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease. Jci Insight. 2: e90807. PMID 28194442 DOI: 10.1172/Jci.Insight.90807 |
0.352 |
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| 2017 |
Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, Sabatini ME, Gao G, Donahoe PK, Pépin D. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137855 DOI: 10.1073/Pnas.1620729114 |
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| 2017 |
Ai J, Li J, Gessler DJ, Su Q, Wei Q, Li H, Gao G. Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery. Scientific Reports. 7: 40336. PMID 28067312 DOI: 10.1038/Srep40336 |
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| 2016 |
Murlidharan G, Sakamoto K, Rao L, Corriher T, Wang D, Gao G, Sullivan P, Asokan A. CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector. Molecular Therapy. Nucleic Acids. 5: e338. PMID 28131242 DOI: 10.1038/mtna.2016.49 |
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| 2016 |
GuhaSarkar D, Neiswender J, Su Q, Gao G, Sena-Esteves M. Intracranial AAV-IFN-β gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model. Molecular Oncology. PMID 28098415 DOI: 10.1002/1878-0261.12020 |
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| 2016 |
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A. RNA activation of haploinsufficient Foxg1 gene in murine neocortex. Scientific Reports. 6: 39311. PMID 27995975 DOI: 10.1038/Srep39311 |
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| 2016 |
Schober AL, Gagarkin DA, Chen Y, Gao G, Jacobson L, Mongin AA. Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo. Frontiers in Cellular Neuroscience. 10: 262. PMID 27891076 DOI: 10.3389/Fncel.2016.00262 |
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| 2016 |
Zhong G, Wang H, Bailey CC, Gao G, Farzan M. Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells. Elife. 5. PMID 27805569 DOI: 10.7554/Elife.18858 |
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| 2016 |
Murlidharan G, Sakamoto K, Rao L, Corriher T, Wang D, Gao G, Sullivan P, Asokan A. CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector. Molecular Therapy. Nucleic Acids. 5: e338. PMID 27434683 DOI: 10.1038/Mtna.2016.49 |
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| 2016 |
Fuchs SP, Martinez-Navio JM, Gao G, Desrosiers RC. Recombinant AAV Vectors for Enhanced Expression of Authentic IgG. Plos One. 11: e0158009. PMID 27332822 DOI: 10.1371/Journal.Pone.0158009 |
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| 2016 |
Zhang H, Lin Y, Li K, Liang J, Xiao X, Cai J, Tan Y, Xing F, Mai J, Li Y, Chen W, Sheng L, Gu J, Zhu W, Yin W, ... ... Gao G, et al. Naturally Existing Oncolytic Virus M1 Is Nonpathogenic for the Non-human Primates after Multiple Rounds of Repeated Intravenous Injections. Human Gene Therapy. PMID 27296553 DOI: 10.1089/Hum.2016.038 |
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| 2016 |
GuhaSarkar D, Su Q, Gao G, Sena-Esteves M. Systemic AAV9-IFNβ gene delivery treats highly invasive glioblastoma. Neuro-Oncology. PMID 27194146 DOI: 10.1093/Neuonc/Now097 |
0.355 |
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| 2016 |
Ahmed SS, Schattgen SA, Frakes AE, Sikoglu EM, Su Q, Li J, Hampton TG, Denninger AR, Kirschner DA, Kaspar B, Matalon R, Gao G. rAAV gene therapy in a Canavan's disease mouse model reveals immune impairments and an extended pathology beyond the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27039844 DOI: 10.1038/Mt.2016.68 |
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| 2016 |
Lu Y, Ai J, Gessler D, Su Q, Tran K, Zheng Q, Xu X, Gao G. Efficient Transduction of Corneal Stroma by Adeno-Associated Virus Serotype Vectors for Implications in Gene Therapy of Corneal Diseases. Human Gene Therapy. PMID 27001051 DOI: 10.1089/Hum.2015.167 |
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| 2016 |
Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, et al. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo. Nature Biotechnology. PMID 26829318 DOI: 10.1038/Nbt.3471 |
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| 2016 |
Gessler DJ, Gao G. Gene Therapy for the Treatment of Neurological Disorders: Metabolic Disorders. Methods in Molecular Biology (Clifton, N.J.). 1382: 429-65. PMID 26611604 DOI: 10.1007/978-1-4939-3271-9_30 |
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| 2016 |
Zhong G, Wang H, Bailey CC, Gao G, Farzan M. Author response: Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells Elife. DOI: 10.7554/Elife.18858.018 |
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| 2016 |
Wang D, Mou H, Tran K, Li J, Wang BY, Gessler DJ, Tai PW, Su Q, Xue W, Gao G. 733. Somatically Repairing Compound Heterozygous Recessive Mutations by Chromosomal Cut-and-Paste for In Vivo Gene Therapy Molecular Therapy. 24: S289. DOI: 10.1016/S1525-0016(16)33541-9 |
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| 2016 |
Wang D, Tran K, Wang BY, Xu G, Li M, Ma H, He R, Su Q, Zamore PD, Gao G. 570. Transient Reconstitution of Cas9 Protein for Safer Gene Editing In Vivo - A Ferry Tale Starring rAAV Capsid Molecular Therapy. 24: S227-S228. DOI: 10.1016/S1525-0016(16)33378-0 |
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| 2016 |
Gessler DJ, Li D, Xu H, Su Q, Matalon R, Gao G. 366. Hitting Two Birds with One Stone: How Efficacious Pre-Clinical Gene Therapy Cures Canavan Disease and Sheds Light onto the Pathomechanism Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33175-6 |
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| 2016 |
Gessler DJ, Li D, Xu H, Su Q, Matalon R, Gao G. 351. Efficacious Non-Oligodendrocyte Gene Therapy Suggests a New Dogma About CNS Compartmentalization of NAA Metabolism and Supports a Metabolic Sink Theory Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33160-4 |
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| 2016 |
Gessler DJ, Li D, Xu H, Su Q, Gao G. 349. The Cure of Canavan Disease: Is It a Scientific Fiction or Clinical Reality? Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33158-6 |
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| 2016 |
Gong Y, Kok R, Mu D, Gao G, Eichler F. 295. Intrathecal Delivery of rAAV9-ABCD1 by Osmotic Pump in a Mouse Model of Adrenomyeloneuropathy Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33104-5 |
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| 2016 |
Ai J, Al-Abbasee R, Gao G. 290. A High-Throughput, Sensitive, Accurate and Reproducible Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33099-4 |
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| 2016 |
Gessler DJ, Huang W, Li D, Xu H, Su Q, King J, Moore C, Gao G. 157. High-Field In Vivo Neuroimaging to Determine CNS Gene Therapy Outcome and Probe Disease Pathomechanism Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32966-5 |
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| 2016 |
Gernoux G, Borel F, Gao G, Brown RH, Mueller C. 90. Vector Biodistribution After Recombinant AAVrh10 Intrathecal Delivery in Non-Human Primates Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32899-4 |
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| 2016 |
Xiao Y, Li S, Su Q, Luo L, Xu G, Qin W, Wang C, Lu Y, Yang L, Wei Y, Gao G. 81. Downregulation of Immune Responsive Chemokines Are Associated AAV8-Mediated Transgene Immune Tolerance Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32890-8 |
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| 2016 |
Gessler DJ, Li D, Xu H, Su Q, Matalon R, Gao G. 58. Pushing the Limits for Canavan Gene Therapy into Adulthood: Is There an Age Limit for Gene Therapy in CNS Disorders? Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32867-2 |
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| 2016 |
Xie J, He R, Su Q, Tai PW, Ma H, Li J, Gao G. 9. rAAV Designs Harboring DNA Secondary Structures with High Thermal Stabilities Produce Heterogenic Viral Genome Populations Molecular Therapy. 24: S5. DOI: 10.1016/S1525-0016(16)32818-0 |
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| 2016 |
Xu G, Luo L, Tai PW, Qin W, Xiao Y, Wang C, Su Q, Ma H, He R, Wei Y, Gao G. 7. High-Throughput Sequencing of AAV Proviral Libraries from the Human Population Reveals Novel Variants with Unprecedented Intra-and Inter-Tissue Diversity Molecular Therapy. 24: S4. DOI: 10.1016/S1525-0016(16)32816-7 |
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| 2016 |
Casal ML, Wang P, ODonnell PA, Sikora T, Langan T, O'Malley T, Ferla R, Auricchio A, Wilson JM, Gao G, Ponder K, Haskins ME. Urinary glycosaminoglycan concentration as a biomarker for effectiveness of enzyme replacement and gene therapy in large animal models of mucopolysaccharidoses Molecular Genetics and Metabolism. 117: S32. DOI: 10.1016/J.Ymgme.2015.12.214 |
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| 2015 |
Choudhury SR, Harris AF, Cabral DJ, Keeler AM, Sapp E, Ferreira JS, Gray-Edwards HL, Johnson JA, Johnson AK, Su Q, Stoica L, DiFiglia M, Aronin N, Martin DR, Gao G, et al. Widespread CNS gene transfer and silencing after systemic delivery of novel AAV-AS vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26708003 DOI: 10.1038/Mt.2015.231 |
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| 2015 |
Rashnonejad A, Chermahini GA, Li S, Ozkinay F, Gao G. Large-Scale Production of Adeno-Associated Viral Vector Serotype-9 Carrying the Human Survival Motor Neuron Gene. Molecular Biotechnology. PMID 26607476 DOI: 10.1007/S12033-015-9899-5 |
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| 2015 |
Schattgen SA, Gao G, Kurt-Jones EA, Fitzgerald KA. Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2. Journal of Immunology (Baltimore, Md. : 1950). PMID 26590313 DOI: 10.4049/Jimmunol.1501048 |
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| 2015 |
Ai J, Wang D, Wei Q, Li H, Gao G. Adeno-associated Virus Serotype Vectors Efficiently Transduce Normal Prostate Tissue and Prostate Cancer Cells. European Urology. PMID 26526960 DOI: 10.1016/J.Eururo.2015.10.019 |
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| 2015 |
Gurda BL, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, Bagel J, Vite CH, Sikora T, Hinderer C, Calcedo R, Yox AD, Steet RA, Ruane T, O'Donnell P, ... Gao G, et al. Evaluation of AAV-mediated gene therapy for central nervous system disease in canine mucopolysaccharidosis VII. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26447927 DOI: 10.1038/Mt.2015.189 |
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| 2015 |
Li S, Ling C, Zhong L, Li M, Su Q, He R, Tang Q, Greiner DL, Shultz LD, Brehm MA, Flotte TR, Mueller C, Srivastava A, Gao G. Efficient and targeted transduction of nonhuman primate liver with systemically delivered optimized AAV3B vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26403887 DOI: 10.1038/Mt.2015.174 |
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| 2015 |
Cahoon JM, Rai RR, Carroll LS, Uehara H, Zhang X, O'Neil CL, Medina RJ, Das SK, Muddana SK, Olson PR, Nielson S, Walker K, Flood MM, Messenger WB, Archer BJ, ... ... Gao G, et al. Intravitreal AAV2.COMP-Ang1 prevents neurovascular degeneration in a murine model of diabetic retinopathy. Diabetes. PMID 26340930 DOI: 10.2337/Db14-1030 |
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| 2015 |
Fuchs SP, Martinez-Navio JM, Piatak M, Lifson JD, Gao G, Desrosiers RC. AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity. Plos Pathogens. 11: e1005090. PMID 26248318 DOI: 10.1371/Journal.Ppat.1005090 |
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| 2015 |
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216943 DOI: 10.1073/Pnas.1510604112 |
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| 2015 |
Li L, He ZY, Wei XW, Gao GP, Wei YQ. Challenges in CRISPR/CAS9 Delivery: Potential Roles of Nonviral Vectors. Human Gene Therapy. 26: 452-62. PMID 26176432 DOI: 10.1089/Hum.2015.069 |
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| 2015 |
Wang D, Mou H, Li S, Li Y, Hough S, Tran K, Li J, Yin H, Anderson DG, Sontheimer EJ, Weng Z, Gao G, Xue W. Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses. Human Gene Therapy. 26: 432-42. PMID 26086867 DOI: 10.1089/Hum.2015.087 |
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| 2015 |
Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, Xu Z. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Molecular Neurobiology. PMID 26050084 DOI: 10.1007/S12035-015-9223-1 |
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| 2015 |
Prendiville TW, Guo H, Lin Z, Zhou P, Stevens SM, He A, VanDusen N, Chen J, Zhong L, Wang DZ, Gao G, Pu WT. Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase. Plos One. 10: e0128105. PMID 26023924 DOI: 10.1371/Journal.Pone.0128105 |
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| 2015 |
Weismann CM, Ferreira J, Keeler AM, Su Q, Qui L, Shaffer SA, Xu Z, Gao G, Sena-Esteves M. Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan. Human Molecular Genetics. 24: 4353-64. PMID 25964428 DOI: 10.1093/Hmg/Ddv168 |
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| 2015 |
Gruntman AM, Su L, Su Q, Gao G, Mueller C, Flotte TR. Stability and compatibility of recombinant adeno-associated virus under conditions commonly encountered in human gene therapy trials. Human Gene Therapy Methods. 26: 71-6. PMID 25819833 DOI: 10.1089/Hgtb.2015.040 |
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| 2015 |
Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, ... ... Gao G, et al. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 519: 87-91. PMID 25707797 DOI: 10.1038/Nature14264 |
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| 2015 |
Pepin D, Sosulski A, Hendren K, Zhang LH, Nicolaou F, Wang D, Gao G, Donahoe PK. Abstract AS25: An adeno-associated virus (AAV) 9 vector delivering modified human mullerian inhibiting substance (MIS) as a gene therapy for ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-As25 |
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| 2015 |
Xie J, Mao Q, He R, Zhu Y, Li J, Su Q, Li M, Zhong L, Muller C, Zhou H, Gao G. 676. DNA Sequences Encoding shRNAs Can Replace Mutant ITR in scAAV Genome for Efficient Replication and Packaging and Transcribe shRNAs by pol III Promoter Activity of wt ITR for Efficient Gene Silencing Molecular Therapy. 23: S269. DOI: 10.1016/S1525-0016(16)34285-X |
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| 2015 |
Kells AP, Goulet M, Aubin J, Yuan S, Dismuke D, Reed RP, Su Q, Gao G, Sah DW, Stewart GR. 502. Optimization of Intrathecal Delivery of AAV for Targeting the Spinal Compartment Molecular Therapy. 23: S200-S201. DOI: 10.1016/S1525-0016(16)34111-9 |
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| 2015 |
Gessler DJ, Li J, Su Q, Matalon R, Gao G. 496. From Gene Therapy to Gene Enhancement: Optimized Pre-Clinical Gene Therapy Transforms Mice with the Severest Canavan Disease Phenotype Into “Supermice” Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34105-3 |
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| 2015 |
Li S, Xiao Y, Su Q, Qin W, Xu G, Luo L, Wang C, Lu Y, Yang L, Wei Y, Gao G. 457. Both Regulatory T and B Cells May Play Roles in Systemic Immune Tolerance Induced by rAAV-Mediated Gene Transfer to Liver Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34066-7 |
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| 2015 |
Gernoux G, Borel F, Gao G, Brown R, Mueller C. 92. Detection and Characterization of Immune Response Against AAVrh10 Vector After Intrathecal Vector Delivery in Non-Human Primates Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33697-8 |
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| 2015 |
Goulet M, Aubin J, Kells AP, Su Q, Yuan S, Ramamoorthi K, Kotin R, McLaughlin J, Gao G, Sah DWY. 86. Comparison of CNS Transduction by Different AAV Capsids in Mouse and Non-Human Primate Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33691-7 |
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| 2015 |
Murlidharan G, Rao L, Wang D, Corriher T, Seok-Oh K, Gao G, Jude Samulski R, Tarantal AF, Asokan A. 14. Next Generation AAV Vectors for Limiting Systemic Leakage and Improving Safety Following CNS Administration Molecular Therapy. 23: S6. DOI: 10.1016/S1525-0016(16)33618-8 |
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| 2014 |
Gao K, Li M, Zhong L, Su Q, Li J, Li S, He R, Zhang Y, Hendricks G, Wang J, Gao G. Empty Virions In AAV8 Vector Preparations Reduce Transduction Efficiency And May Cause Total Viral Particle Dose-Limiting Side-Effects. Molecular Therapy. Methods & Clinical Development. 1: 20139. PMID 25485285 DOI: 10.1038/Mtm.2013.9 |
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| 2014 |
Ling C, Wang Y, Zhang Y, Ejjigani A, Yin Z, Lu Y, Wang L, Wang M, Li J, Hu Z, Aslanidi GV, Zhong L, Gao G, Srivastava A, Ling C. Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model. Human Gene Therapy. 25: 1023-34. PMID 25296041 DOI: 10.1089/Hum.2014.099 |
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| 2014 |
Ayuso E, Blouin V, Lock M, McGorray S, Leon X, Alvira MR, Auricchio A, Bucher S, Chtarto A, Clark KR, Darmon C, Doria M, Fountain W, Gao G, Gao K, et al. Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material. Human Gene Therapy. 25: 977-87. PMID 25275822 DOI: 10.1089/Hum.2014.057 |
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| 2014 |
Wang D, Gao G. State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications. Discovery Medicine. 18: 151-61. PMID 25227756 |
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| 2014 |
Wang D, Gao G. State-of-the-art human gene therapy: part I. Gene delivery technologies. Discovery Medicine. 18: 67-77. PMID 25091489 |
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| 2014 |
Vincent M, Gao G, Jacobson L. Comparison of the efficacy of five adeno-associated virus vectors for transducing dorsal raphé nucleus cells in the mouse. Journal of Neuroscience Methods. 235: 189-92. PMID 25046366 DOI: 10.1016/J.Jneumeth.2014.07.005 |
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| 2014 |
Yang B, Li S, Wang H, Guo Y, Gessler DJ, Cao C, Su Q, Kramer J, Zhong L, Ahmed SS, Zhang H, He R, Desrosiers RC, Brown R, Xu Z, ... Gao G, et al. Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1299-309. PMID 24781136 DOI: 10.1038/Mt.2014.68 |
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| 2014 |
Xu H, Zhang L, Gu L, Lu L, Gao G, Li W, Xu G, Wang J, Gao F, Xu JY, Yao J, Wang F, Zhang J, Xu GT. Subretinal delivery of AAV2-mediated human erythropoietin gene is protective and safe in experimental diabetic retinopathy. Investigative Ophthalmology & Visual Science. 55: 1519-30. PMID 24508793 DOI: 10.1167/Iovs.13-13155 |
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| 2014 |
Wang D, Zhong L, Nahid MA, Gao G. The potential of adeno-associated viral vectors for gene delivery to muscle tissue. Expert Opinion On Drug Delivery. 11: 345-64. PMID 24386892 DOI: 10.1517/17425247.2014.871258 |
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| 2014 |
Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, Guo Y, Brown RH, Gao G, Xu Z. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 668-81. PMID 24108104 DOI: 10.1093/Hmg/Ddt454 |
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| 2013 |
van der Bom IM, Moser RP, Gao G, Mondo E, O'Connell D, Gounis MJ, McGowan S, Chaurette J, Bishop N, Sena-Esteves MS, Mueller C, Aronin N. Finding the striatum in sheep: use of a multi-modal guided approach for convection enhanced delivery. Journal of Huntington's Disease. 2: 41-5. PMID 25063428 DOI: 10.3233/Jhd-130053 |
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| 2013 |
Limberis MP, Racine T, Kobasa D, Li Y, Gao GF, Kobinger G, Wilson JM. Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9. Clinical and Vaccine Immunology : Cvi. 20: 1836-7. PMID 24132603 DOI: 10.1128/Cvi.00545-13 |
0.364 |
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| 2013 |
Zhong L, Li S, Li M, Xie J, Zhang Y, Lee B, Batshaw ML, Wilson JM, Gao G. Vector sequences are not detected in tumor tissue from research subjects with ornithine transcarbamylase deficiency who previously received adenovirus gene transfer. Human Gene Therapy. 24: 814-9. PMID 24010702 DOI: 10.1089/Hum.2013.118 |
0.487 |
|
| 2013 |
Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, ... ... Gao G, et al. A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2136-47. PMID 23817205 DOI: 10.1038/Mt.2013.138 |
0.404 |
|
| 2013 |
Ahmed SS, Li J, Godwin J, Gao G, Zhong L. Gene transfer in the liver using recombinant adeno-associated virus. Current Protocols in Microbiology. Unit14D.6. PMID 23686826 DOI: 10.1002/9780471729259.Mc14D06S29 |
0.439 |
|
| 2013 |
Stoica L, Ahmed SS, Gao G, Sena-Esteves M. Gene transfer to the CNS using recombinant adeno-associated virus. Current Protocols in Microbiology. Unit14D.5. PMID 23686825 DOI: 10.1002/9780471729259.Mc14D05S29 |
0.448 |
|
| 2013 |
Zhong L, Malani N, Li M, Brady T, Xie J, Bell P, Li S, Jones H, Wilson JM, Flotte TR, Bushman FD, Gao G. Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction. Human Gene Therapy. 24: 520-5. PMID 23621841 DOI: 10.1089/Hum.2012.112 |
0.481 |
|
| 2013 |
Song L, Li X, Jayandharan GR, Wang Y, Aslanidi GV, Ling C, Zhong L, Gao G, Yoder MC, Ling C, Tan M, Srivastava A. High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. Plos One. 8: e58757. PMID 23516552 DOI: 10.1371/Journal.Pone.0058757 |
0.418 |
|
| 2013 |
Luo L, Zhang X, Hirano Y, Tyagi P, Barabás P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, ... ... Gao G, et al. Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration. Acs Nano. 7: 3264-75. PMID 23464925 DOI: 10.1021/Nn305958Y |
0.321 |
|
| 2013 |
Ahmed SS, Gao G. Gene therapy for Canavan's disease takes a step forward. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 505-6. PMID 23449107 DOI: 10.1038/Mt.2013.25 |
0.388 |
|
| 2013 |
Venkatesh A, Ma S, Langellotto F, Gao G, Punzo C. Retinal gene delivery by rAAV and DNA electroporation. Current Protocols in Microbiology. Unit 14D.4. PMID 23408132 DOI: 10.1002/9780471729259.Mc14D04S28 |
0.391 |
|
| 2013 |
Gruntman AM, Bish LT, Mueller C, Sweeney HL, Flotte TR, Gao G. Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus. Current Protocols in Microbiology. Unit 14D.3. PMID 23408131 DOI: 10.1002/9780471729259.Mc14D03S28 |
0.45 |
|
| 2013 |
Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, ... ... Gao G, et al. Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 266-8. PMID 23369965 DOI: 10.1038/Mt.2013.4 |
0.487 |
|
| 2013 |
Velez G, Weingarden AR, Lei H, Kazlauskas A, Gao G. SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified Müller cell-induced rabbit models. Investigative Ophthalmology & Visual Science. 54: 1392-7. PMID 23341018 DOI: 10.1167/Iovs.12-10320 |
0.301 |
|
| 2013 |
Sun L, Tu L, Gao G, Sun X, Duan J, Lu Y. Assessment of a passive immunity mouse model to quantitatively analyze the impact of neutralizing antibodies on adeno-associated virus-mediated gene transfer. Journal of Immunological Methods. 387: 114-20. PMID 23063691 DOI: 10.1016/J.Jim.2012.10.003 |
0.422 |
|
| 2012 |
Gruntman AM, Mueller C, Flotte TR, Gao G. Gene transfer in the lung using recombinant adeno-associated virus. Current Protocols in Microbiology. Unit14D.2. PMID 22875566 DOI: 10.1002/9780471729259.Mc14D02S26 |
0.415 |
|
| 2012 |
Mueller C, Ratner D, Zhong L, Esteves-Sena M, Gao G. Production and discovery of novel recombinant adeno-associated viral vectors. Current Protocols in Microbiology. Unit14D.1. PMID 22875565 DOI: 10.1002/9780471729259.Mc14D01S26 |
0.408 |
|
| 2012 |
Beckett T, Bonneau L, Howard A, Blanchard J, Borda J, Weiner DJ, Wang L, Gao GP, Kolls JK, Bohm R, Liggitt D, Weiss DJ. Inhalation of nebulized perfluorochemical enhances recombinant adenovirus and adeno-associated virus-mediated gene expression in lung epithelium. Human Gene Therapy Methods. 23: 98-110. PMID 22568624 DOI: 10.1089/Hgtb.2012.014 |
0.324 |
|
| 2011 |
Gao G, Zhong L, Danos O. Exploiting natural diversity of AAV for the design of vectors with novel properties. Methods in Molecular Biology (Clifton, N.J.). 807: 93-118. PMID 22034027 DOI: 10.1007/978-1-61779-370-7_4 |
0.411 |
|
| 2011 |
Bell P, Wang L, Gao G, Haskins ME, Tarantal AF, McCarter RJ, Zhu Y, Yu H, Wilson JM. Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates. Molecular Genetics and Metabolism. 104: 395-403. PMID 21778099 DOI: 10.1016/J.Ymgme.2011.06.002 |
0.53 |
|
| 2011 |
Zhang H, Yang B, Mu X, Ahmed SS, Su Q, He R, Wang H, Mueller C, Sena-Esteves M, Brown R, Xu Z, Gao G. Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1440-8. PMID 21610699 DOI: 10.1038/Mt.2011.98 |
0.409 |
|
| 2011 |
Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM. The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice. The Journal of Clinical Investigation. 121: 2427-35. PMID 21576824 DOI: 10.1172/Jci57367 |
0.529 |
|
| 2011 |
Gao G, Bish LT, Sleeper MM, Mu X, Sun L, Lou Y, Duan J, Hu C, Wang L, Sweeney HL. Transendocardial delivery of AAV6 results in highly efficient and global cardiac gene transfer in rhesus macaques. Human Gene Therapy. 22: 979-84. PMID 21563985 DOI: 10.1089/Hum.2011.042 |
0.451 |
|
| 2011 |
Bish LT, Sleeper MM, Reynolds C, Gazzara J, Withnall E, Singletary GE, Buchlis G, Hui D, High KA, Gao G, Wilson JM, Sweeney HL. Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines. Human Gene Therapy. 22: 969-77. PMID 21542669 DOI: 10.1089/Hum.2011.035 |
0.481 |
|
| 2011 |
Lu J, Wang Q, Wang H, Li G, Gao G. Molecular characterization of adenoviruses in fecal samples of captively bred rhesus macaques in China. Veterinary Microbiology. 149: 461-6. PMID 21215533 DOI: 10.1016/J.Vetmic.2010.12.005 |
0.3 |
|
| 2011 |
Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM. Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs. Human Gene Therapy. 22: 985-97. PMID 21204705 DOI: 10.1089/Hum.2010.194 |
0.54 |
|
| 2011 |
Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, ... ... Gao G, et al. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 526-35. PMID 21179009 DOI: 10.1038/Mt.2010.279 |
0.324 |
|
| 2010 |
Goodman AL, Epp C, Moss D, Holder AA, Wilson JM, Gao GP, Long CA, Remarque EJ, Thomas AW, Ammendola V, Colloca S, Dicks MD, Biswas S, Seibel D, van Duivenvoorde LM, et al. New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1. Infection and Immunity. 78: 4601-12. PMID 20713623 DOI: 10.1128/Iai.00315-10 |
0.382 |
|
| 2010 |
Jakovcevski M, Guo Y, Su Q, Gao G, Akbarian S. rAAV9--a human-derived adeno-associated virus vector for efficient transgene expression in mouse cingulate cortex. Cold Spring Harbor Protocols. 2010: pdb.prot5417. PMID 20360371 DOI: 10.1101/Pdb.Prot5417 |
0.425 |
|
| 2010 |
Sun X, Lu Y, Bish LT, Calcedo R, Wilson JM, Gao G. Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate models. Human Gene Therapy. 21: 750-61. PMID 20113166 DOI: 10.1089/Hum.2009.214 |
0.518 |
|
| 2010 |
Maguire CA, Gianni D, Meijer DH, Shaket LA, Wakimoto H, Rabkin SD, Gao G, Sena-Esteves M. Directed evolution of adeno-associated virus for glioma cell transduction. Journal of Neuro-Oncology. 96: 337-47. PMID 19618115 DOI: 10.1007/S11060-009-9972-7 |
0.423 |
|
| 2009 |
Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A, Johnston J, Debyser Z, Agbandje-McKenna M, Wilson JM. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. Gene Therapy. 16: 1416-28. PMID 19727141 DOI: 10.1038/Gt.2009.101 |
0.52 |
|
| 2009 |
Zhang H, Xie J, Xie Q, Wilson JM, Gao G. Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production. Human Gene Therapy. 20: 922-9. PMID 19618999 DOI: 10.1089/Hum.2009.125 |
0.514 |
|
| 2009 |
Gao G, Wang Q, Calcedo R, Mays L, Bell P, Wang L, Vandenberghe LH, Grant R, Sanmiguel J, Furth EE, Wilson JM. Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses. Human Gene Therapy. 20: 930-42. PMID 19441963 DOI: 10.1089/Hum.2009.060 |
0.556 |
|
| 2009 |
Pichla-Gollon SL, Lin SW, Hensley SE, Lasaro MO, Herkenhoff-Haut L, Drinker M, Tatsis N, Gao GP, Wilson JM, Ertl HC, Bergelson JM. Effect of preexisting immunity on an adenovirus vaccine vector: in vitro neutralization assays fail to predict inhibition by antiviral antibody in vivo. Journal of Virology. 83: 5567-73. PMID 19279092 DOI: 10.1128/Jvi.00405-09 |
0.515 |
|
| 2009 |
Calcedo R, Vandenberghe LH, Gao G, Lin J, Wilson JM. Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses. The Journal of Infectious Diseases. 199: 381-90. PMID 19133809 DOI: 10.1086/595830 |
0.484 |
|
| 2009 |
Vandenberghe LH, Wilson JM, Gao G. Tailoring the AAV vector capsid for gene therapy. Gene Therapy. 16: 311-9. PMID 19052631 DOI: 10.1038/Gt.2008.170 |
0.549 |
|
| 2008 |
Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Lee Sweeney H. Percutaneous Transendocardial Delivery of Self-complementary Adeno-associated Virus 6 Achieves Global Cardiac Gene Transfer in Canines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1953-1959. PMID 28189009 DOI: 10.1038/Mt.2008.202 |
0.538 |
|
| 2008 |
Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL. Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1953-9. PMID 18813281 DOI: 10.1038/mt.2008.202 |
0.468 |
|
| 2008 |
Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL. Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Human Gene Therapy. 19: 1359-68. PMID 18795839 DOI: 10.1089/Hum.2008.123 |
0.485 |
|
| 2008 |
Gao G, Wang Q, Dai Z, Calcedo R, Sun X, Li G, Wilson JM. Adenovirus-based vaccines generate cytotoxic T lymphocytes to epitopes of NS1 from dengue virus that are present in all major serotypes. Human Gene Therapy. 19: 927-36. PMID 18788905 DOI: 10.1089/Hum.2008.011 |
0.461 |
|
| 2008 |
Reyes-Sandoval A, Sridhar S, Berthoud T, Moore AC, Harty JT, Gilbert SC, Gao G, Ertl HC, Wilson JC, Hill AV. Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei. European Journal of Immunology. 38: 732-41. PMID 18266272 DOI: 10.1002/Eji.200737672 |
0.354 |
|
| 2008 |
Sridhar S, Reyes-Sandoval A, Draper SJ, Moore AC, Gilbert SC, Gao GP, Wilson JM, Hill AV. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. Journal of Virology. 82: 3822-33. PMID 18256155 DOI: 10.1128/Jvi.02568-07 |
0.47 |
|
| 2008 |
Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney L. AAV9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat Human Gene Therapy. 81015093227032. DOI: 10.1089/Hgt.2008.123 |
0.479 |
|
| 2007 |
Alton E, Ferrari S, Griesenbach U, Aiuti A, Bachoud-Lévi AC, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, et al. Progress and prospects: gene therapy clinical trials (part 2). Gene Therapy. 14: 1555-63. PMID 17984995 DOI: 10.1038/sj.gt.3303033 |
0.342 |
|
| 2007 |
Kobinger GP, Figueredo JM, Rowe T, Zhi Y, Gao G, Sanmiguel JC, Bell P, Wivel NA, Zitzow LA, Flieder DB, Hogan RJ, Wilson JM. Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques. Vaccine. 25: 5220-31. PMID 17559989 DOI: 10.1016/J.Vaccine.2007.04.065 |
0.453 |
|
| 2007 |
Tatsis N, Blejer A, Lasaro MO, Hensley SE, Cun A, Tesema L, Li Y, Gao GP, Xiang ZQ, Zhou D, Wilson JM, Ertl HC. A CD46-binding chimpanzee adenovirus vector as a vaccine carrier. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 608-17. PMID 17228314 DOI: 10.1038/Sj.Mt.6300078 |
0.524 |
|
| 2007 |
Pichla-Gollon SL, Drinker M, Zhou X, Xue F, Rux JJ, Gao GP, Wilson JM, Ertl HC, Burnett RM, Bergelson JM. Structure-based identification of a major neutralizing site in an adenovirus hexon. Journal of Virology. 81: 1680-9. PMID 17108028 DOI: 10.1128/Jvi.02023-06 |
0.44 |
|
| 2006 |
Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates". Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 150. PMID 28192691 DOI: 10.1016/J.Ymthe.2006.04.002 |
0.509 |
|
| 2006 |
Vandenberghe LH, Wang L, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, Wilson JM. Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid. Nature Medicine. 12: 967-71. PMID 16845388 DOI: 10.1038/Nm1445 |
0.507 |
|
| 2006 |
Kelkar S, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL. A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes. Journal of Virology. 80: 7781-5. PMID 16840360 DOI: 10.1128/Jvi.00481-06 |
0.416 |
|
| 2006 |
Kitajima K, Marchadier DH, Miller GC, Gao GP, Wilson JM, Rader DJ. Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1852-7. PMID 16763161 DOI: 10.1161/01.Atv.0000231520.26490.54 |
0.523 |
|
| 2006 |
Gao GP, Lu Y, Sun X, Johnston J, Calcedo R, Grant R, Wilson JM. High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes. Journal of Virology. 80: 6192-4. PMID 16731960 DOI: 10.1128/Jvi.00526-06 |
0.548 |
|
| 2006 |
Zhi Y, Figueredo J, Kobinger GP, Hagan H, Calcedo R, Miller JR, Gao G, Wilson JM. Efficacy of severe acute respiratory syndrome vaccine based on a nonhuman primate adenovirus in the presence of immunity against human adenovirus. Human Gene Therapy. 17: 500-6. PMID 16716107 DOI: 10.1089/Hum.2006.17.500 |
0.474 |
|
| 2006 |
Bell P, Moscioni AD, McCarter RJ, Wu D, Gao G, Hoang A, Sanmiguel JC, Sun X, Wivel NA, Raper SE, Furth EE, Batshaw ML, Wilson JM. Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 34-44. PMID 16682254 DOI: 10.1016/J.Ymthe.2006.03.008 |
0.5 |
|
| 2006 |
Moscioni D, Morizono H, McCarter RJ, Stern A, Cabrera-Luque J, Hoang A, Sanmiguel J, Wu D, Bell P, Gao GP, Raper SE, Wilson JM, Batshaw ML. Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 25-33. PMID 16677864 DOI: 10.1016/J.Ymthe.2006.03.009 |
0.525 |
|
| 2006 |
Kobinger GP, Feldmann H, Zhi Y, Schumer G, Gao G, Feldmann F, Jones S, Wilson JM. Chimpanzee adenovirus vaccine protects against Zaire Ebola virus. Virology. 346: 394-401. PMID 16356525 DOI: 10.1016/J.Virol.2005.10.042 |
0.447 |
|
| 2006 |
Tatsis N, Tesema L, Robinson ER, Giles-Davis W, McCoy K, Gao GP, Wilson JM, Ertl HC. Chimpanzee-origin adenovirus vectors as vaccine carriers. Gene Therapy. 13: 421-9. PMID 16319951 DOI: 10.1038/Sj.Gt.3302675 |
0.385 |
|
| 2006 |
De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG. High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 67-76. PMID 16260185 DOI: 10.1016/J.Ymthe.2005.09.003 |
0.542 |
|
| 2006 |
Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 77-87. PMID 16219492 DOI: 10.1016/J.Ymthe.2005.08.017 |
0.561 |
|
| 2006 |
Shifrin AL, Chirmule N, Gao GP, Wilson JM, Raper SE. Innate immune responses to adenoviral vector-mediated acute pancreatitis. Pancreas. 30: 122-9. PMID 15714134 DOI: 10.1097/01.Mpa.0000151578.99413.88 |
0.431 |
|
| 2006 |
Vandenberge LH, Breous K, Gao G, McMenamin D, Munden RL, Duc TN, Wilson JM. 744. Novel Vectors for Gene Therapy: Covering the Spectrum of Primate AAV Diversity Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.826 |
0.566 |
|
| 2006 |
Somanthan S, Zhang Z, Gao G, Lock MW, Bell PL, Roy S, Sandhi AK, Wilson JM. 609. Acute-Phase Toxicity Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Mice Molecular Therapy. 13: S235. DOI: 10.1016/J.Ymthe.2006.08.683 |
0.481 |
|
| 2006 |
Bell PL, Moscioni AD, McCarter RJ, Wu D, Gao G, Hoang A, San Miguel J, Sun X, Wivel N, Raper SE, Furth EE, Batshaw ML, Wilson JM. 206. Frequency and Analysis of Liver Tumors in AAV-Treated B6C3F1 Hybrid Mice Molecular Therapy. 13: S80. DOI: 10.1016/J.Ymthe.2006.08.231 |
0.496 |
|
| 2006 |
Zhang Z, Zhi Y, Figueredo JM, Calcedo R, Miller JR, Gao G, Wilson JM. 77. TLR and Myd88 Signaling Pathway Is Required for the Full Induction of Host Adaptive Immune Responses to Adenoviral Vectors and Transgenes Molecular Therapy. 13: S33. DOI: 10.1016/J.Ymthe.2006.08.094 |
0.472 |
|
| 2006 |
Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates" (DOI:10.1016/j.ymthe.2005.08.017) Molecular Therapy. 14: 150. DOI: 10.1016/j.ymthe.2006.04.002 |
0.435 |
|
| 2005 |
Zhang H, Gao G, Clayburne G, Schumacher HR. Elimination of rheumatoid synovium in situ using a Fas ligand 'gene scalpel'. Arthritis Research & Therapy. 7: R1235-43. PMID 16277676 DOI: 10.1186/Ar1811 |
0.347 |
|
| 2005 |
Bell P, Wang L, Lebherz C, Flieder DB, Bove MS, Wu D, Gao GP, Wilson JM, Wivel NA. No evidence for tumorigenesis of AAV vectors in a large-scale study in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 299-306. PMID 16043099 DOI: 10.1016/J.Ymthe.2005.03.020 |
0.39 |
|
| 2005 |
Gao G, Vandenberghe LH, Wilson JM. New recombinant serotypes of AAV vectors. Current Gene Therapy. 5: 285-97. PMID 15975006 DOI: 10.2174/1566523054065057 |
0.572 |
|
| 2005 |
Bell P, Limberis M, Gao G, Wu D, Bove MS, Sanmiguel JC, Wilson JM. An optimized protocol for detection of E. coli beta-galactosidase in lung tissue following gene transfer. Histochemistry and Cell Biology. 124: 77-85. PMID 15947941 DOI: 10.1007/S00418-005-0793-2 |
0.452 |
|
| 2005 |
Zhi Y, Kobinger GP, Jordan H, Suchma K, Weiss SR, Shen H, Schumer G, Gao G, Boyer JL, Crystal RG, Wilson JM. Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein. Virology. 335: 34-45. PMID 15823604 DOI: 10.1016/J.Virol.2005.01.050 |
0.466 |
|
| 2005 |
Jennings K, Miyamae T, Traister R, Marinov A, Katakura S, Sowders D, Trapnell B, Wilson JM, Gao G, Hirsch R. Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 600-7. PMID 15771962 DOI: 10.1016/J.Ymthe.2004.10.020 |
0.474 |
|
| 2005 |
Varnavski AN, Calcedo R, Bove M, Gao G, Wilson JM. Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice. Gene Therapy. 12: 427-436. PMID 15647774 DOI: 10.1038/Sj.Gt.3302347 |
0.489 |
|
| 2005 |
Rivera VM, Gao GP, Grant RL, Schnell MA, Zoltick PW, Rozamus LW, Clackson T, Wilson JM. Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood. 105: 1424-30. PMID 15507527 DOI: 10.1182/Blood-2004-06-2501 |
0.552 |
|
| 2005 |
Kobinger GP, Rowe T, Gao G, Figueredo JM, Sanmiguel J, Bell P, Hogan RJ, Wilson JM. 1092. Adenovirus-Based Vaccine Prevents Pneumonia in Ferrets Challenged with the SARS Coronavirus Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.639 |
0.477 |
|
| 2005 |
Zhi Y, Wu D, Jordan H, Gao G, Wilson JM. 1089. Examine the Cross-Reactivity of Vector-Specific T Cells between Human Adenoviral H5 and Simian Adenoviral C7 Vector in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.636 |
0.53 |
|
| 2005 |
Somanathan S, Roy S, Gao G, Sandhu A, Wilson JM. 872. Chimpanzee Derived Adenoviral Vectors Transduce and Activate Human Dendritic Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.415 |
0.51 |
|
| 2005 |
Kelkar SA, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL. 847. Adeno-Associated Virus Capsids from Divergent AAV Clades and Subgroup C Adenovirus Capsids Share a Common Microtubule-Binding Mechanism Relevant to Virus Trafficking Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.390 |
0.456 |
|
| 2005 |
De BP, Heguy A, Hackett NR, Lee J, Gao G, Wilson JM, Crystal RG. 812. Non-Human Primate Serotype rh.10 AAV Directed Therapeutic Serum Levels of |[alpha]|1-antitrypsin Following Intrapleural Administration in Mice with Pre-Existing Immunity to AAV Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.349 |
0.404 |
|
| 2005 |
Sondhi D, Peterson DA, Vassallo E, Sanders CT, Stratton JA, Hackett NR, Gao G, Wilson JM, Crystal RG. 660. Quantitative Comparison of AAV Serotypes AAV2, AAV5, and AAVrh.10 Efficiency for CNS Gene Therapy Following Intracranial Gene Delivery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.200 |
0.557 |
|
| 2005 |
De BP, Heguy A, Hackett NR, Gao G, Wilson JM, Crystal RG. 508. Impact of Sex on Serum |[alpha]|1-Antitrypsin Levels Following Intrapleural and Intravenous Administration of AAVrh.10 Vectors to Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.048 |
0.45 |
|
| 2005 |
Lu Y, Gao G, Sanmiguel J, Calcedo R, Bell P, Wivel N, Wilson JM. 506. Transductional and Genome Biodistribution of Novel AAV Serotype Vectors after Systemic Delivery and Their Liver Specific Dose Response Profiles in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.046 |
0.506 |
|
| 2005 |
Vandenberghe LH, Yang MH, Johnston J, Gao G, Wilson JM. 503. Mutational Strategy To Enhance or Rescue Functionality of Existing AAV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.043 |
0.53 |
|
| 2005 |
Gao G, Lu Y, Calcedo R, Grant R, Sanmiguel J, Wang L, Johnston J, Figueredo J, Lock M, Wilson JM. 500. Biology of Novel AAV Serotype Vectors in the Liver Directed Gene Transfer to Nonhuman Primates Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.040 |
0.575 |
|
| 2005 |
Zhou X, Gao G, Owens RA, Lu Y, Calcedo R, Miller J, Wilson JM. 404. Roles of Inverted Terminal Repeats (ITRs) and Capsid Proteins from Novel NHP AAVs in rAAV Mediated Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.407 |
0.554 |
|
| 2005 |
Kobinger GP, Feldmann H, Zhi Y, Schumer G, Gao G, Feldmann F, Jones S, Wilson JM. 141. Adenovirus Vaccine to Ebola Virus: Mechanism of Protection and Impact of Pre-Existing Immunity to the Vaccine Carrier Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.146 |
0.481 |
|
| 2005 |
Figueredo J, Calcedo R, Miller J, Kobinger G, Grant R, Gao G, Wilson JM. 139. Priming and Boosting Efficiency of Chimp and Human Adenoviral Vectors in the Setting of Pre-Existing Immunity in Non-Human Primates Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.144 |
0.479 |
|
| 2005 |
Zhi Y, Johnston J, Wu D, Figueredo J, Lock M, Bell P, Gao G, Wilson JM. 112. Strong Transgene-Specific Immune Responses Can Be Elicited with Novel Adeno-Associated Virus Vectors in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.117 |
0.538 |
|
| 2004 |
Katakura S, Jennings K, Watanabe S, Adachi E, Thornton S, Gao GP, Wilson JM, Burstein H, Trapnell B, Hirsch R. Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy. Modern Rheumatology / the Japan Rheumatism Association. 14: 18-24. PMID 17028800 DOI: 10.1007/S10165-003-0260-7 |
0.523 |
|
| 2004 |
Vais H, Gao GP, Yang M, Tran P, Louboutin JP, Somanathan S, Wilson JM, Reenstra WW. Novel adenoviral vectors coding for GFP-tagged wtCFTR and ΔF508-CFTR: Characterization of expression and electrophysiological properties in A549 cells Pflugers Archiv European Journal of Physiology. 449: 278-287. PMID 15452712 DOI: 10.1007/S00424-004-1331-0 |
0.452 |
|
| 2004 |
Hogan RJ, Gao G, Rowe T, Bell P, Flieder D, Paragas J, Kobinger GP, Wivel NA, Crystal RG, Boyer J, Feldmann H, Voss TG, Wilson JM. Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1. Journal of Virology. 78: 11416-21. PMID 15452265 DOI: 10.1128/Jvi.78.20.11416-11421.2004 |
0.44 |
|
| 2004 |
Rowe T, Gao G, Hogan RJ, Crystal RG, Voss TG, Grant RL, Bell P, Kobinger GP, Wivel NA, Wilson JM. Macaque model for severe acute respiratory syndrome. Journal of Virology. 78: 11401-4. PMID 15452262 DOI: 10.1128/Jvi.78.20.11401-11404.2004 |
0.404 |
|
| 2004 |
Roy S, Gao G, Clawson DS, Vandenberghe LH, Farina SF, Wilson JM. Complete nucleotide sequences and genome organization of four chimpanzee adenoviruses. Virology. 324: 361-72. PMID 15207622 DOI: 10.1016/J.Virol.2004.03.047 |
0.45 |
|
| 2004 |
Lebherz C, Gao G, Louboutin JP, Millar J, Rader D, Wilson JM. Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia. The Journal of Gene Medicine. 6: 663-72. PMID 15170737 DOI: 10.1002/Jgm.554 |
0.547 |
|
| 2004 |
Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, Wilson JM. Clades of Adeno-associated viruses are widely disseminated in human tissues. Journal of Virology. 78: 6381-8. PMID 15163731 DOI: 10.1128/Jvi.78.12.6381-6388.2004 |
0.518 |
|
| 2004 |
Roy S, Gao G, Lu Y, Zhou X, Lock M, Calcedo R, Wilson JM. Characterization of a family of chimpanzee adenoviruses and development of molecular clones for gene transfer vectors. Human Gene Therapy. 15: 519-30. PMID 15144581 DOI: 10.1089/10430340460745838 |
0.563 |
|
| 2004 |
Ziegler RJ, Lonning SM, Armentano D, Li C, Souza DW, Cherry M, Ford C, Barbon CM, Desnick RJ, Gao G, Wilson JM, Peluso R, Godwin S, Carter BJ, Gregory RJ, et al. AAV2 vector harboring a liver-restricted promoter facilitates sustained expression of therapeutic levels of alpha-galactosidase A and the induction of immune tolerance in Fabry mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 231-40. PMID 14759807 DOI: 10.1016/J.Ymthe.2003.11.015 |
0.522 |
|
| 2004 |
Gao G, Lebherz C, Weiner DJ, Grant R, Calcedo R, McCullough B, Bagg A, Zhang Y, Wilson JM. Erythropoietin gene therapy leads to autoimmune anemia in macaques. Blood. 103: 3300-2. PMID 14695227 DOI: 10.1182/Blood-2003-11-3852 |
0.551 |
|
| 2004 |
Sarkar R, Tetreault R, Gao G, Wang L, Bell P, Chandler R, Wilson JM, Kazazian HH. Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype. Blood. 103: 1253-60. PMID 14551134 DOI: 10.1182/Blood-2003-08-2954 |
0.562 |
|
| 2004 |
Rivera VM, Berk L, Wardwell S, Tang H, Gao G, Grant RL, Wilson JM, Clackson T. 1048. Long-Term Regulated Gene Expression in Non-Human Primates Using a Single Non-Recombinogenic AAV Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.993 |
0.525 |
|
| 2004 |
Roy S, Zhi Y, Clawson D, Gao G, Kobinger GP, Wilson JM. 1016. Novel Chimeric Adenovirus Vaccine Vectors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.961 |
0.564 |
|
| 2004 |
Limberis M, Gao G, Weiner DJ, Wang L, Bell P, Wilson JM. 692. A novel AAV vector for the treatment of cystic fibrosis airway disease Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.598 |
0.519 |
|
| 2004 |
Zhi Y, Wang L, Gao G, Wilson JM. 569. Increased Antigen-Specific Humoral Response by Adenoviral Vector Prime and Adeno-Associated Viral Vector Boost Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.492 |
0.51 |
|
| 2004 |
Zhi Y, Kobinger GP, Jordan H, Gao G, Wilson JM. 568. Comparison of Antigen-Specific Immune Responses Elicited by Recombinant Simian Adenoviral Vectors with Deletions in Either E1, or E1/E3, or E1/E4 Regions Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.491 |
0.489 |
|
| 2004 |
Kobinger GP, Feldmann H, Zhi Y, Schumer GP, Gao G, Feldmann F, Jones S, Wilson JM. 373. Simian Adenoviral Vector Based-Vaccine Fully Protect Against Ebola Virus Even in the Presence of Pre-Existing Immunity to Human Adenovirus Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.317 |
0.485 |
|
| 2004 |
De BP, Wasif N, Hackett NR, Gao G, Wilson JM, Crystal RG. 338. Therapeutic Levels for |[alpha]|1-Antitrypsin Following Intrapleural Administration of a Non-Human Primate Serotype rh10 AAV Vector Expressing |[alpha]|1-Antitrypsin Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.280 |
0.497 |
|
| 2004 |
Zhou X, Gao G, Owens RA, Calcedo R, Wilson JM. 90. Evaluation of Novel Gene Transfer Vectors Derived from Infectious Molecular Clones of Primate AAVs Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.025 |
0.569 |
|
| 2004 |
Vandenberghe LH, Gao G, Alvira MR, Calcedo R, Wilson JM. 88. AAV clades: Their Ability To Recombine and Cross Species-Barriers Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.024 |
0.497 |
|
| 2003 |
Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP, Wilson JM, Batshaw ML. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Molecular Genetics and Metabolism. 80: 148-58. PMID 14567964 DOI: 10.1016/J.Ymgme.2003.08.016 |
0.513 |
|
| 2003 |
Xiang Z, Li Y, Gao G, Wilson JM, Ertl HC. Mucosally delivered E1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 4287-93. PMID 14530353 DOI: 10.4049/Jimmunol.171.8.4287 |
0.516 |
|
| 2003 |
Gao G, Zhou X, Alvira MR, Tran P, Marsh J, Lynd K, Xiao W, Wilson JM. High throughput creation of recombinant adenovirus vectors by direct cloning, green-white selection and I-Sce I-mediated rescue of circular adenovirus plasmids in 293 cells. Gene Therapy. 10: 1926-30. PMID 14502222 DOI: 10.1038/Sj.Gt.3302088 |
0.55 |
|
| 2003 |
Johnston J, Tazelaar J, Rivera VM, Clackson T, Gao GP, Wilson JM. Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 493-7. PMID 12727112 DOI: 10.1016/S1525-0016(03)00043-1 |
0.541 |
|
| 2003 |
Varnavski AN, Schlienger K, Bergelson JM, Gao GP, Wilson JM. Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector. Human Gene Therapy. 14: 533-44. PMID 12718764 DOI: 10.1089/104303403764539323 |
0.489 |
|
| 2003 |
Gao G, Alvira MR, Somanathan S, Lu Y, Vandenberghe LH, Rux JJ, Calcedo R, Sanmiguel J, Abbas Z, Wilson JM. Adeno-associated viruses undergo substantial evolution in primates during natural infections. Proceedings of the National Academy of Sciences of the United States of America. 100: 6081-6. PMID 12716974 DOI: 10.1073/Pnas.0937739100 |
0.503 |
|
| 2003 |
Fitzgerald JC, Gao GP, Reyes-Sandoval A, Pavlakis GN, Xiang ZQ, Wlazlo AP, Giles-Davis W, Wilson JM, Ertl HC. A simian replication-defective adenoviral recombinant vaccine to HIV-1 gag. Journal of Immunology (Baltimore, Md. : 1950). 170: 1416-22. PMID 12538702 DOI: 10.4049/Jimmunol.170.3.1416 |
0.471 |
|
| 2002 |
Green AP, Huang JJ, Scott MO, Kierstead TD, Beaupré I, Gao GP, Wilson JM. A new scalable method for the purification of recombinant adenovirus vectors. Human Gene Therapy. 13: 1921-34. PMID 12427304 DOI: 10.1089/10430340260355338 |
0.478 |
|
| 2002 |
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 99: 11854-9. PMID 12192090 DOI: 10.1073/Pnas.182412299 |
0.582 |
|
| 2002 |
Auricchio A, O'Connor E, Weiner D, Gao GP, Hildinger M, Wang L, Calcedo R, Wilson JM. Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins. The Journal of Clinical Investigation. 110: 499-504. PMID 12189244 DOI: 10.1172/Jci15780 |
0.561 |
|
| 2002 |
Varnavski AN, Zhang Y, Schnell M, Tazelaar J, Louboutin JP, Yu QC, Bagg A, Gao GP, Wilson JM. Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity. Journal of Virology. 76: 5711-9. PMID 11991999 DOI: 10.1128/Jvi.76.11.5711-5719.2002 |
0.517 |
|
| 2002 |
Gao GP, Lu F, Sanmiguel JC, Tran PT, Abbas Z, Lynd KS, Marsh J, Spinner NB, Wilson JM. Rep/Cap gene amplification and high-yield production of AAV in an A549 cell line expressing Rep/Cap. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 644-9. PMID 11991756 DOI: 10.1006/Mthe.2001.0591 |
0.493 |
|
| 2002 |
Xiang Z, Gao G, Reyes-Sandoval A, Cohen CJ, Li Y, Bergelson JM, Wilson JM, Ertl HC. Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. Journal of Virology. 76: 2667-75. PMID 11861833 DOI: 10.1128/Jvi.76.6.2667-2675.2002 |
0.484 |
|
| 2002 |
Raper SE, Yudkoff M, Chirmule N, Gao GP, Nunes F, Haskal ZJ, Furth EE, Propert KJ, Robinson MB, Magosin S, Simoes H, Speicher L, Hughes J, Tazelaar J, Wivel NA, et al. A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency. Human Gene Therapy. 13: 163-75. PMID 11779420 DOI: 10.1089/10430340152712719 |
0.492 |
|
| 2002 |
Cohen CJ, Xiang ZQ, Gao GP, Ertl HC, Wilson JM, Bergelson JM. Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor. The Journal of General Virology. 83: 151-5. PMID 11752711 DOI: 10.1099/0022-1317-83-1-151 |
0.501 |
|
| 2001 |
Farina SF, Gao GP, Xiang ZQ, Rux JJ, Burnett RM, Alvira MR, Marsh J, Ertl HC, Wilson JM. Replication-defective vector based on a chimpanzee adenovirus. Journal of Virology. 75: 11603-13. PMID 11689642 DOI: 10.1128/Jvi.75.23.11603-11613.2001 |
0.501 |
|
| 2001 |
Hildinger M, Auricchio A, Gao G, Wang L, Chirmule N, Wilson JM. Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer. Journal of Virology. 75: 6199-203. PMID 11390622 DOI: 10.1128/Jvi.75.13.6199-6203.2001 |
0.542 |
|
| 2001 |
Schnell MA, Zhang Y, Tazelaar J, Gao GP, Yu QC, Qian R, Chen SJ, Varnavski AN, LeClair C, Raper SE, Wilson JM. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 708-22. PMID 11356076 DOI: 10.1006/Mthe.2001.0330 |
0.514 |
|
| 2001 |
Zoltick PW, Chirmule N, Schnell MA, Gao G, Hughes JV, Wilson JM. Biology of E1-Deleted Adenovirus Vectors in Nonhuman Primate Muscle Journal of Virology. 75: 5222-5229. PMID 11333904 DOI: 10.1128/Jvi.75.11.5222-5229.2001 |
0.559 |
|
| 2001 |
Cordier L, Gao GP, Hack AA, McNally EM, Wilson JM, Chirmule N, Sweeney HL. Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. Human Gene Therapy. 12: 205-15. PMID 11177557 DOI: 10.1089/104303401750061267 |
0.539 |
|
| 2001 |
Auricchio A, Hildinger M, O'Connor E, Gao GP, Wilson JM. Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. Human Gene Therapy. 12: 71-6. PMID 11177544 DOI: 10.1089/104303401450988 |
0.525 |
|
| 2001 |
Tao N, Gao GP, Parr M, Johnston J, Baradet T, Wilson JM, Barsoum J, Fawell SE. Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 28-35. PMID 11162308 DOI: 10.1006/Mthe.2000.0227 |
0.486 |
|
| 2001 |
Gao GP, Wilson JM, Wivel NA. Production of recombinant adeno-associated virus. Advances in Virus Research. 55: 529-43. PMID 11050955 DOI: 10.1016/S0065-3527(00)55016-7 |
0.576 |
|
| 2001 |
Jennings K, Katakura S, Burstein H, Gao G, Wilson J, Hirsch R. Adeno-associated virus preferentially transduces human compared to mouse synovium Arthritis Research & Therapy. 3: 1-14. DOI: 10.1186/Ar334 |
0.538 |
|
| 2000 |
Gao G, Qu G, Burnham MS, Huang J, Chirmule N, Joshi B, Yu QC, Marsh JA, Conceicao CM, Wilson JM. Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo Human Gene Therapy. 11: 2079-2091. PMID 11044910 DOI: 10.1089/104303400750001390 |
0.546 |
|
| 2000 |
Chen SJ, Rader DJ, Tazelaar J, Kawashiri M, Gao G, Wilson JM. Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 256-61. PMID 10985956 DOI: 10.1006/Mthe.2000.0122 |
0.495 |
|
| 2000 |
Watanabe S, Imagawa T, Boivin GP, Gao G, Wilson JM, Hirsch R. Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 147-52. PMID 10947942 DOI: 10.1006/Mthe.2000.0111 |
0.532 |
|
| 2000 |
Zhang Y, Chirmule N, Gao G, Wilson J. CD40 Ligand-Dependent Activation of Cytotoxic T Lymphocytes by Adeno-Associated Virus Vectors In Vivo: Role of Immature Dendritic Cells Journal of Virology. 74: 8003-8010. PMID 10933709 DOI: 10.1128/Jvi.74.17.8003-8010.2000 |
0.549 |
|
| 2000 |
Gao GP, Engdahl RK, Wilson JM. A cell line for high-yield production of E1-deleted adenovirus vectors without the emergence of replication-competent virus. Human Gene Therapy. 11: 213-9. PMID 10646652 DOI: 10.1089/10430340050016283 |
0.516 |
|
| 2000 |
Yu Q, Ma X, Croyle M, Qu G, Huang J, Gao G, Hughes J, Wilson J. Electron Microscopic Evaluation of Vector Quality for Gene Therapy Microscopy and Microanalysis. 6: 858-859. DOI: 10.1017/S1431927600036783 |
0.459 |
|
| 1999 |
Grifman M, Chen NN, Gao GP, Cathomen T, Wilson JM, Weitzman MD. Overexpression of cyclin A inhibits augmentation of recombinant adeno-associated virus transduction by the adenovirus E4orf6 protein. Journal of Virology. 73: 10010-9. PMID 10559315 DOI: 10.1128/Jvi.73.12.10010-10019.1999 |
0.512 |
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| 1999 |
Bennett J, Maguire AM, Cideciyan AV, Schnell M, Glover E, Anand V, Aleman TS, Chirmule N, Gupta AR, Huang Y, Gao GP, Nyberg WC, Tazelaar J, Hughes J, Wilson JM, et al. Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proceedings of the National Academy of Sciences of the United States of America. 96: 9920-5. PMID 10449795 DOI: 10.1073/Pnas.96.17.9920 |
0.535 |
|
| 1999 |
Xiao W, Chirmule N, Berta SC, McCullough B, Gao G, Wilson JM. Gene therapy vectors based on adeno-associated virus type 1. Journal of Virology. 73: 3994-4003. PMID 10196295 DOI: 10.1128/Jvi.73.5.3994-4003.1999 |
0.571 |
|
| 1999 |
Lanuti M, Gao GP, Force SD, Chang MY, El Kouri C, Amin KM, Hughes JV, Wilson JM, Kaiser LR, Albelda SM. Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy. Human Gene Therapy. 10: 463-75. PMID 10048398 DOI: 10.1089/10430349950018904 |
0.57 |
|
| 1999 |
Ye X, Rivera VM, Zoltick P, Cerasoli F, Schnell MA, Gao G, Hughes JV, Gilman M, Wilson JM. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. Science (New York, N.Y.). 283: 88-91. PMID 9872748 DOI: 10.1126/Science.283.5398.88 |
0.536 |
|
| 1999 |
Wivel NA, Gao G, Wilson JM. 5 Adenovirus Vectors Cold Spring Harbor Monograph Archive. 36: 87-110. DOI: 10.1101/087969528.36.87 |
0.555 |
|
| 1998 |
Gao GP, Qu G, Faust LZ, Engdahl RK, Xiao W, Hughes JV, Zoltick PW, Wilson JM. High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus. Human Gene Therapy. 9: 2353-62. PMID 9829534 DOI: 10.1089/Hum.1998.9.16-2353 |
0.564 |
|
| 1998 |
Chirmule N, Hughes JV, Gao G, Raper SE, Wilson JM. Role of E4 in Eliciting CD4 T-Cell and B-Cell Responses to Adenovirus Vectors Delivered to Murine and Nonhuman Primate Lungs Journal of Virology. 72: 6138-6145. PMID 9621078 DOI: 10.1128/Jvi.72.7.6138-6145.1998 |
0.477 |
|
| 1998 |
Raper SE, Haskal ZJ, Ye X, Pugh C, Furth EE, Gao GP, Wilson JM. Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses. Human Gene Therapy. 9: 671-9. PMID 9551615 DOI: 10.1089/Hum.1998.9.5-671 |
0.505 |
|
| 1998 |
Raper S, Batshaw ML, Ye X, Gao G, Wilson JM. Comparative toxicity of E4 deleted vectors expressing human ornithine transcarbamylase (OTC) cDNA ♦ 730 Pediatric Research. 43: 127-127. DOI: 10.1203/00006450-199804001-00751 |
0.475 |
|
| 1996 |
Fisher KJ, Gao GP, Weitzman MD, DeMatteo R, Burda JF, Wilson JM. Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. Journal of Virology. 70: 520-32. PMID 8523565 DOI: 10.1128/Jvi.70.1.520-532.1996 |
0.558 |
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