| Year |
Citation |
Score |
| 2020 |
Santos LPA, Assunção LDP, Lima PS, Tristão GB, Brock M, Borges CL, Silva-Bailão MG, Soares CMA, Bailão AM. Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses. Ima Fungus. 11: 9. PMID 32617258 DOI: 10.1186/s43008-020-00029-9 |
0.312 |
|
| 2019 |
Vanherp L, Ristani A, Poelmans J, Hillen A, Lagrou K, Janbon G, Brock M, Himmelreich U, Velde GV. Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis. Disease Models & Mechanisms. PMID 31101657 DOI: 10.1242/Dmm.039123 |
0.32 |
|
| 2019 |
Araújo DS, Pereira M, Portis IG, Dos Santos Junior ACM, Fontes W, de Sousa MV, Assunção LDP, Baeza LC, Bailão AM, Ricart CAO, Brock M, Soares CMA. Metabolic Peculiarities of Dimorphism as Demonstrated by iTRAQ Labeling Proteomics. Frontiers in Microbiology. 10: 555. PMID 30949151 DOI: 10.3389/Fmicb.2019.00555 |
0.344 |
|
| 2018 |
de Assis LJ, Manfiolli A, Mattos E, Fabri JHTM, Malavazi I, Jacobsen ID, Brock M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH. Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in . Mbio. 9. PMID 30538182 DOI: 10.1128/Mbio.01952-18 |
0.359 |
|
| 2018 |
Geib E, Baldeweg F, Doerfer M, Nett M, Brock M. Cross-Chemistry Leads to Product Diversity from Atromentin Synthetases in Aspergilli from Section Nigri. Cell Chemical Biology. PMID 30527997 DOI: 10.1016/J.Chembiol.2018.10.021 |
0.351 |
|
| 2018 |
Persyn A, Rogiers O, Brock M, Vande Velde G, Lamkanfi M, Jacobsen ID, Himmelreich U, Lagrou K, Van Dijck P, Kucharíková S. Monitoring of fluconazole and caspofungin activity against in vivo biofilms by bioluminescence imaging. Antimicrobial Agents and Chemotherapy. PMID 30420485 DOI: 10.1128/Aac.01555-18 |
0.31 |
|
| 2018 |
Poelmans J, Himmelreich U, Vanherp L, Zhai L, Hillen A, Holvoet B, Belderbos S, Brock M, Maertens J, Velde GV, Lagrou K. A multimodal imaging approach enables assessment of antifungal treatment in a mouse model of invasive pulmonary aspergillosis. Antimicrobial Agents and Chemotherapy. PMID 29760132 DOI: 10.1128/Aac.00240-18 |
0.311 |
|
| 2017 |
Hsieh SH, Brock M. Lipid components of bile increase the protective effect of conjugated bile salts against antifungal drugs. Fungal Biology. 121: 929-938. PMID 29029700 DOI: 10.1016/J.Funbio.2017.08.002 |
0.314 |
|
| 2017 |
Brandenburger E, Gressler M, Leonhardt R, Lackner G, Habel A, Hertweck C, Brock M, Hoffmeister D. A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore. Applied and Environmental Microbiology. PMID 28842536 DOI: 10.1128/Aem.01478-17 |
0.359 |
|
| 2017 |
Hsieh SH, Brunke S, Brock M. Encapsulation of Antifungals in Micelles Protects Candida albicans during Gall-Bladder Infection. Frontiers in Microbiology. 8: 117. PMID 28203228 DOI: 10.3389/Fmicb.2017.00117 |
0.375 |
|
| 2016 |
Naranjo-Ortíz MA, Brock M, Brunke S, Hube B, Marcet-Houben M, Gabaldón T. Widespread Inter- and Intra-Domain Horizontal Gene Transfer of d-Amino Acid Metabolism Enzymes in Eukaryotes. Frontiers in Microbiology. 7: 2001. PMID 28066338 DOI: 10.3389/Fmicb.2016.02001 |
0.353 |
|
| 2016 |
Kalleda N, Amich J, Arslan B, Poreddy S, Mattenheimer K, Mokhtari Z, Einsele H, Brock M, Heinze KG, Beilhack A. Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens. Frontiers in Microbiology. 7: 1107. PMID 27468286 DOI: 10.3389/Fmicb.2016.01107 |
0.327 |
|
| 2016 |
Geib E, Gressler M, Viediernikova I, Hillmann F, Jacobsen ID, Nietzsche S, Hertweck C, Brock M. A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress. Cell Chemical Biology. PMID 27133313 DOI: 10.1016/J.Chembiol.2016.03.014 |
0.39 |
|
| 2016 |
Funk J, Schaarschmidt B, Slesiona S, Hallström T, Horn U, Brock M. The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species. International Journal of Medical Microbiology : Ijmm. 306: 59-68. PMID 26679571 DOI: 10.1016/J.Ijmm.2015.11.005 |
0.38 |
|
| 2016 |
Kalleda N, Amich J, Poreddy S, Arslan B, Friedrich M, Mokhtari Z, Ottmüller K, Jordán-Garrote A, Einsele H, Brock M, Heinze KG, Beilhack A. Corticosteroids Impair Granulocyte Transfusion Therapy By Targeting NET Formation and Neutrophil Antifungal Functions Via ROS/Dectin1 Pathways Blood. 128: 2506-2506. DOI: 10.1182/Blood.V128.22.2506.2506 |
0.341 |
|
| 2015 |
Gressler M, Meyer F, Heine D, Hortschansky P, Hertweck C, Brock M. Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals. Elife. 4. PMID 26173180 DOI: 10.7554/Elife.07861 |
0.305 |
|
| 2015 |
Gressler M, Hortschansky P, Geib E, Brock M. A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster. Frontiers in Microbiology. 6: 184. PMID 25852654 DOI: 10.3389/Fmicb.2015.00184 |
0.322 |
|
| 2014 |
Papon N, Courdavault V, Lanoue A, Clastre M, Brock M. Illuminating fungal infections with bioluminescence. Plos Pathogens. 10: e1004179. PMID 25010008 DOI: 10.1371/Journal.Ppat.1004179 |
0.312 |
|
| 2014 |
Jacobsen ID, Lüttich A, Kurzai O, Hube B, Brock M. In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. The Journal of Antimicrobial Chemotherapy. 69: 2785-96. PMID 24951534 DOI: 10.1093/Jac/Dku198 |
0.346 |
|
| 2014 |
Zaehle C, Gressler M, Shelest E, Geib E, Hertweck C, Brock M. Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity. Chemistry & Biology. 21: 719-31. PMID 24816227 DOI: 10.1016/J.Chembiol.2014.03.010 |
0.364 |
|
| 2014 |
Brunke S, Seider K, Richter ME, Bremer-Streck S, Ramachandra S, Kiehntopf M, Brock M, Hube B. Histidine degradation via an aminotransferase increases the nutritional flexibility of Candida glabrata. Eukaryotic Cell. 13: 758-65. PMID 24728193 DOI: 10.1128/Ec.00072-14 |
0.415 |
|
| 2014 |
Ramachandra S, Linde J, Brock M, Guthke R, Hube B, Brunke S. Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. Plos One. 9: e92734. PMID 24651113 DOI: 10.1371/Journal.Pone.0092734 |
0.371 |
|
| 2014 |
Otzen C, Bardl B, Jacobsen ID, Nett M, Brock M. Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA. The Journal of Biological Chemistry. 289: 8151-69. PMID 24497638 DOI: 10.1074/Jbc.M113.517672 |
0.462 |
|
| 2013 |
Otzen C, Müller S, Jacobsen ID, Brock M. Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans. Fems Yeast Research. 13: 553-64. PMID 23758791 DOI: 10.1111/1567-1364.12057 |
0.396 |
|
| 2013 |
Fazius F, Zaehle C, Brock M. Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production. Applied Microbiology and Biotechnology. 97: 3763-72. PMID 23504110 DOI: 10.1007/S00253-013-4805-1 |
0.31 |
|
| 2012 |
Fazius F, Shelest E, Gebhardt P, Brock M. The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate Molecular Microbiology. 86: 1508-1530. PMID 23106124 DOI: 10.1111/Mmi.12076 |
0.415 |
|
| 2012 |
Citiulo F, Jacobsen ID, Miramón P, Schild L, Brunke S, Zipfel P, Brock M, Hube B, Wilson D. Candida albicans scavenges host zinc via Pra1 during endothelial invasion. Plos Pathogens. 8: e1002777. PMID 22761575 DOI: 10.1371/Journal.Ppat.1002777 |
0.334 |
|
| 2012 |
Slesiona S, Ibrahim-Granet O, Olias P, Brock M, Jacobsen ID. Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration. The Journal of Infectious Diseases. 205: 1268-77. PMID 22438397 DOI: 10.1093/Infdis/Jis193 |
0.337 |
|
| 2012 |
Fekkar A, Pionneau C, Brossas JY, Marinach-Patrice C, Snounou G, Brock M, Ibrahim-Granet O, Mazier D. DIGE enables the detection of a putative serum biomarker of fungal origin in a mouse model of invasive aspergillosis. Journal of Proteomics. 75: 2536-49. PMID 22370163 DOI: 10.1016/J.Jprot.2012.01.040 |
0.347 |
|
| 2012 |
Slesiona S, Gressler M, Mihlan M, Zaehle C, Schaller M, Barz D, Hube B, Jacobsen ID, Brock M. Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages Plos One. 7. PMID 22319619 DOI: 10.1371/Journal.Pone.0031223 |
0.347 |
|
| 2012 |
Jouvion G, Brock M, Droin-Bergère S, Ibrahim-Granet O. Duality of liver and kidney lesions after systemic infection of immunosuppressed and immunocompetent mice with Aspergillus fumigatus. Virulence. 3: 43-50. PMID 22286702 DOI: 10.4161/Viru.3.1.18654 |
0.315 |
|
| 2012 |
Brock M. Application of bioluminescence imaging for in vivo monitoring of fungal infections. International Journal of Microbiology. 2012: 956794. PMID 22121368 DOI: 10.1155/2012/956794 |
0.343 |
|
| 2011 |
Fleck CB, Schöbel F, Brock M. Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization. International Journal of Medical Microbiology : Ijmm. 301: 400-7. PMID 21550848 DOI: 10.1016/J.Ijmm.2011.04.007 |
0.382 |
|
| 2011 |
Cruz AH, Brock M, Zambuzzi-Carvalho PF, Santos-Silva LK, Troian RF, Góes AM, Soares CM, Pereira M. Phosphorylation is the major mechanism regulating isocitrate lyase activity in Paracoccidioides brasiliensis yeast cells. The Febs Journal. 278: 2318-32. PMID 21535474 DOI: 10.1111/J.1742-4658.2011.08150.X |
0.382 |
|
| 2011 |
Müller S, Fleck CB, Wilson D, Hummert C, Hube B, Brock M. Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases. Environmental Microbiology. 13: 1534-48. PMID 21453403 DOI: 10.1111/J.1462-2920.2011.02458.X |
0.395 |
|
| 2011 |
Gressler M, Zaehle C, Scherlach K, Hertweck C, Brock M. Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. Chemistry & Biology. 18: 198-209. PMID 21236704 DOI: 10.1016/J.Chembiol.2010.12.011 |
0.36 |
|
| 2011 |
Olias P, Gruber AD, Hafez HM, Lierz M, Slesiona S, Brock M, Jacobsen ID. Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment. Veterinary Microbiology. 148: 348-55. PMID 20880638 DOI: 10.1016/J.Vetmic.2010.08.029 |
0.351 |
|
| 2010 |
Fleck CB, Brock M. Aspergillus fumigatus catalytic glucokinase and hexokinase: expression analysis and importance for germination, growth, and conidiation. Eukaryotic Cell. 9: 1120-35. PMID 20453072 DOI: 10.1128/Ec.00362-09 |
0.402 |
|
| 2010 |
Jacobsen ID, Grosse K, Slesiona S, Hube B, Berndt A, Brock M. Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infection and Immunity. 78: 2995-3006. PMID 20421382 DOI: 10.1128/Iai.00268-10 |
0.369 |
|
| 2010 |
Ibrahim-Granet O, Jouvion G, Hohl TM, Droin-Bergère S, Philippart F, Kim OY, Adib-Conquy M, Schwendener R, Cavaillon JM, Brock M. In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis. Bmc Microbiology. 10: 105. PMID 20377900 DOI: 10.1186/1471-2180-10-105 |
0.304 |
|
| 2010 |
Schöbel F, Jacobsen ID, Brock M. Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. Eukaryotic Cell. 9: 878-93. PMID 20363898 DOI: 10.1128/Ec.00020-10 |
0.451 |
|
| 2010 |
Brunke S, Seider K, Almeida RS, Heyken A, Fleck CB, Brock M, Barz D, Rupp S, Hube B. Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Molecular Microbiology. 76: 25-47. PMID 20199593 DOI: 10.1111/J.1365-2958.2010.07052.X |
0.395 |
|
| 2009 |
Brock M. Back to the roots. Microbial Biotechnology. 2: 132-3. PMID 21261892 DOI: 10.1111/J.1751-7915.2009.00090_4.X |
0.344 |
|
| 2009 |
Domin N, Wilson D, Brock M. Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA-generating carbon sources. Microbiology (Reading, England). 155: 3903-12. PMID 19661181 DOI: 10.1099/Mic.0.031781-0 |
0.402 |
|
| 2009 |
Brock M. Fungal metabolism in host niches. Current Opinion in Microbiology. 12: 371-6. PMID 19535285 DOI: 10.1016/J.Mib.2009.05.004 |
0.373 |
|
| 2009 |
Fleck CB, Brock M. Re-characterisation of Saccharomyces cerevisiae Ach1p: fungal CoA-transferases are involved in acetic acid detoxification. Fungal Genetics and Biology : Fg & B. 46: 473-85. PMID 19298859 DOI: 10.1016/J.Fgb.2009.03.004 |
0.391 |
|
| 2008 |
Brock M, Jouvion G, Droin-Bergère S, Dussurget O, Nicola MA, Ibrahim-Granet O. Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis. Applied and Environmental Microbiology. 74: 7023-35. PMID 18820063 DOI: 10.1128/Aem.01288-08 |
0.338 |
|
| 2008 |
Fleck CB, Brock M. Characterization of an acyl-CoA: carboxylate CoA-transferase from Aspergillus nidulans involved in propionyl-CoA detoxification. Molecular Microbiology. 68: 642-56. PMID 18331473 DOI: 10.1111/J.1365-2958.2008.06180.X |
0.443 |
|
| 2008 |
Ibrahim-Granet O, Dubourdeau M, Latgé JP, Ave P, Huerre M, Brakhage AA, Brock M. Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis. Cellular Microbiology. 10: 134-48. PMID 17973657 DOI: 10.1111/J.1462-5822.2007.01025.X |
0.445 |
|
| 2007 |
Schöbel F, Ibrahim-Granet O, Avé P, Latgé JP, Brakhage AA, Brock M. Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis. Infection and Immunity. 75: 1237-44. PMID 17178786 DOI: 10.1128/Iai.01416-06 |
0.393 |
|
| 2006 |
Sugareva V, Härtl A, Brock M, Hübner K, Rohde M, Heinekamp T, Brakhage AA. Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus. Archives of Microbiology. 186: 345-55. PMID 16988817 DOI: 10.1007/S00203-006-0144-2 |
0.37 |
|
| 2006 |
Ebel F, Schwienbacher M, Beyer J, Heesemann J, Brakhage AA, Brock M. Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development. Fungal Genetics and Biology : Fg & B. 43: 476-89. PMID 16603391 DOI: 10.1016/J.Fgb.2006.01.015 |
0.419 |
|
| 2005 |
Brock M. Generation and phenotypic characterization of Aspergillus nidulans methylisocitrate lyase deletion mutants: methylisocitrate inhibits growth and conidiation. Applied and Environmental Microbiology. 71: 5465-75. PMID 16151139 DOI: 10.1128/Aem.71.9.5465-5475.2005 |
0.38 |
|
| 2005 |
Maerker C, Rohde M, Brakhage AA, Brock M. Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia. The Febs Journal. 272: 3615-30. PMID 16008561 DOI: 10.1111/J.1742-4658.2005.04784.X |
0.467 |
|
| 2004 |
Zhang YQ, Brock M, Keller NP. Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans. Genetics. 168: 785-94. PMID 15514053 DOI: 10.1534/Genetics.104.027540 |
0.399 |
|
| 2004 |
Brock M, Buckel W. On the mechanism of action of the antifungal agent propionate. Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans European Journal of Biochemistry. 271: 3227-3241. PMID 15265042 DOI: 10.1111/J.1432-1033.2004.04255.X |
0.579 |
|
| 2004 |
Liebmann B, Mühleisen TW, Müller M, Hecht M, Weidner G, Braun A, Brock M, Brakhage AA. Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis. Archives of Microbiology. 181: 378-83. PMID 15052376 DOI: 10.1007/S00203-004-0667-3 |
0.404 |
|
| 2003 |
Grimm C, Evers A, Brock M, Maerker C, Klebe G, Buckel W, Reuter K. Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre Journal of Molecular Biology. 328: 609-621. PMID 12706720 DOI: 10.1016/S0022-2836(03)00358-9 |
0.554 |
|
| 2003 |
Hetzel M, Brock M, Selmer T, Pierik AJ, Golding BT, Buckel W. Acryloyl-CoA reductase from Clostridium propionicum: An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein European Journal of Biochemistry. 270: 902-910. PMID 12603323 DOI: 10.1046/J.1432-1033.2003.03450.X |
0.563 |
|
| 2002 |
Brock M, Maerker C, Schütz A, Völker U, Buckel W. Oxidation of propionate to pyruvate in Escherichia coli: Involvement of methylcitrate dehydratase and aconitase European Journal of Biochemistry. 269: 6184-6194. PMID 12473114 DOI: 10.1046/J.1432-1033.2002.03336.X |
0.578 |
|
| 2001 |
Geißenhöner A, Sievers N, Brock M, Fischer R. Aspergillus nidulans DigA, a potential homolog of Saccharomyces cerevisiae Pep3 (Vps18), is required for nuclear migration, mitochondrial morphology and polarized growth. Molecular Genetics and Genomics. 266: 672-685. PMID 11810240 DOI: 10.1007/S00438-001-0589-6 |
0.342 |
|
| 2001 |
Brock M, Darley D, Textor S, Buckel W. 2-Methylisocitrate lyases from the bacterium Escherichia coli and the filamentous fungus Aspergillus nidulans: Characterization and comparison of both enzymes European Journal of Biochemistry. 268: 3577-3586. PMID 11422389 DOI: 10.1046/J.1432-1327.2001.02262.X |
0.582 |
|
| 2000 |
Brock M, Fischer R, Linder D, Buckel W. Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent. Molecular Microbiology. 35: 961-73. PMID 10712680 DOI: 10.1046/J.1365-2958.2000.01737.X |
0.604 |
|
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