Xiao-Bing Gao - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Neurophysiology, synaptic plasticity

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lv H, Catarino J, Li D, Liu B, Gao XB, Horvath TL, Huang Y. A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300015120. PMID 37036983 DOI: 10.1073/pnas.2300015120  0.351
2022 Xie D, Stutz B, Li F, Chen F, Lv H, Sestan-Pesa M, Catarino J, Gu J, Zhao H, Stoddard CE, Carmichael GG, Shanabrough M, Taylor HS, Liu ZW, Gao XB, et al. TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons. The Journal of Clinical Investigation. 132. PMID 36189793 DOI: 10.1172/JCI162365  0.35
2022 Stutz B, Waterson MJ, Šestan-Peša M, Dietrich MO, Škarica M, Sestan N, Racz B, Magyar A, Sotonyi P, Liu ZW, Gao XB, Matyas F, Stoiljkovic M, Horvath TL. AgRP neurons control structure and function of the medial prefrontal cortex. Molecular Psychiatry. PMID 35906488 DOI: 10.1038/s41380-022-01691-8  0.355
2021 Yasumoto Y, Stoiljkovic M, Kim JD, Sestan-Pesa M, Gao XB, Diano S, Horvath TL. Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior. Molecular Psychiatry. PMID 33879866 DOI: 10.1038/s41380-021-01105-1  0.305
2021 Varela L, Stutz B, Song JE, Kim JG, Liu ZW, Gao XB, Horvath TL. Hunger-promoting AgRP neurons trigger an astrocyte-mediated feed-forward auto-activation loop in mice. The Journal of Clinical Investigation. PMID 33848272 DOI: 10.1172/JCI144239  0.371
2020 Crouse RB, Kim K, Batchelor HM, Girardi EM, Kamaletdinova R, Chan J, Rajebhosale P, Pittenger ST, Role LW, Talmage DA, Jing M, Li Y, Gao XB, Mineur YS, Picciotto MR. Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances learning of cue-reward contingency. Elife. 9. PMID 32945260 DOI: 10.7554/Elife.57335  0.313
2020 Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajos M, Lu L, de Lecea L, de Araujo I, Picciotto M, Horvath TL, ... Gao XB, et al. Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. The Journal of Clinical Investigation. PMID 32516139 DOI: 10.1172/Jci130889  0.372
2019 Berger JM, Singh P, Khrimian L, Morgan DA, Chowdhury S, Arteaga-Solis E, Horvath TL, Domingos AI, Marsland AL, Kumal Yadav V, Rahmouni K, Gao XB, Karsenty G. Mediation of the Acute Stress Response by the Skeleton. Cell Metabolism. PMID 31523009 DOI: 10.1016/J.Cmet.2019.08.012  0.332
2019 Stutz B, Nasrallah C, Nigro M, Curry D, Liu ZW, Gao XB, Elsworth JD, Mintz L, Horvath TL. Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity. Molecular Metabolism. PMID 30833218 DOI: 10.1016/J.Molmet.2019.02.005  0.421
2018 Han W, Tellez LA, Perkins MH, Perez IO, Qu T, Ferreira J, Ferreira TL, Quinn D, Liu ZW, Gao XB, Kaelberer MM, Bohórquez DV, Shammah-Lagnado SJ, de Lartigue G, de Araujo IE. A Neural Circuit for Gut-Induced Reward. Cell. PMID 30245012 DOI: 10.1016/J.Cell.2018.08.049  0.309
2017 Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G. Gpr158 mediates osteocalcin's regulation of cognition. The Journal of Experimental Medicine. PMID 28851741 DOI: 10.1084/Jem.20171320  0.329
2017 Suyama S, Ralevski A, Liu ZW, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao XB, Diano S, Horvath TL. Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons. Elife. 6. PMID 28762946 DOI: 10.7554/Elife.25755  0.338
2017 Varela L, Suyama S, Huang Y, Shanabrough M, Tschoep MH, Gao XB, Giordano FJ, Horvath TL. Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons. Diabetes. PMID 28292966 DOI: 10.2337/db16-1106  0.369
2017 Suyama S, Ralevski A, Liu Z, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao X, Diano S, Horvath TL. Author response: Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons Elife. DOI: 10.7554/Elife.25755.014  0.367
2016 Gao XB, Horvath TL. Feeding Behavior: Hypocretin/Orexin Neurons Act between Food Seeking and Eating. Current Biology : Cb. 26: R845-R847. PMID 27676302 DOI: 10.1016/j.cub.2016.07.069  0.31
2016 Zhu Y, Hu J, He W, Gao X, Ren P, Chen H. DDPH, a novel antihypertensive agent, is a potential dual inhibitor of hepatic CYP2D and CYP3A. Chemico-Biological Interactions. PMID 26827781 DOI: 10.1016/j.cbi.2016.01.019  0.347
2015 Gao XB, Hermes G. Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals. Frontiers in Systems Neuroscience. 9: 142. PMID 26539086 DOI: 10.3389/Fnsys.2015.00142  0.406
2015 Zhou WL, Gao XB, Picciotto MR. Acetylcholine Acts through Nicotinic Receptors to Enhance the Firing Rate of a Subset of Hypocretin Neurons in the Mouse Hypothalamus through Distinct Presynaptic and Postsynaptic Mechanisms(.) Eneuro. 2. PMID 26322330 DOI: 10.1523/ENEURO.0052-14.2015  0.328
2015 Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, ... Gao XB, et al. Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature. 519: 45-50. PMID 25707796 DOI: 10.1038/Nature14260  0.43
2013 Rao Y, Mineur YS, Gan G, Wang AH, Liu ZW, Wu X, Suyama S, de Lecea L, Horvath TL, Picciotto MR, Gao XB. Repeated in vivo exposure of cocaine induces long-lasting synaptic plasticity in hypocretin/orexin-producing neurons in the lateral hypothalamus in mice. The Journal of Physiology. 591: 1951-66. PMID 23318871 DOI: 10.1113/jphysiol.2012.246983  0.397
2013 Aldad TS, Gan G, Gao X, Taylor HS. Erratum: CORRIGENDUM: Fetal Radiofrequency Radiation Exposure From 800-1900 Mhz-Rated Cellular Telephones Affects Neurodevelopment and Behavior in Mice Scientific Reports. 3. DOI: 10.1038/srep01320  0.337
2012 Dietrich MO, Bober J, Ferreira JG, Tellez LA, Mineur YS, Souza DO, Gao XB, Picciotto MR, Araújo I, Liu ZW, Horvath TL. AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors. Nature Neuroscience. 15: 1108-10. PMID 22729177 DOI: 10.1038/Nn.3147  0.435
2012 Gao XB. Plasticity in neurons synthesizing wake/arousal promoting hormone hypocretin/orexin. Vitamins and Hormones. 89: 35-59. PMID 22640607 DOI: 10.1016/B978-0-12-394623-2.00003-2  0.446
2012 Aldad TS, Gan G, Gao XB, Taylor HS. Fetal radiofrequency radiation exposure from 800-1900 mhz-rated cellular telephones affects neurodevelopment and behavior in mice. Scientific Reports. 2: 312. PMID 22428084 DOI: 10.1038/srep00312  0.337
2011 Trinko R, Gan G, Gao XB, Sears RM, Guarnieri DJ, DiLeone RJ. Erk1/2 mediates leptin receptor signaling in the ventral tegmental area. Plos One. 6: e27180. PMID 22076135 DOI: 10.1371/Journal.Pone.0027180  0.347
2011 Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, ... ... Gao XB, et al. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nature Medicine. 17: 1121-7. PMID 21873987 DOI: 10.1038/Nm.2421  0.305
2011 Liu ZW, Gan G, Suyama S, Gao XB. Intracellular energy status regulates activity in hypocretin/orexin neurones: a link between energy and behavioural states. The Journal of Physiology. 589: 4157-66. PMID 21727218 DOI: 10.1113/jphysiol.2011.212514  0.355
2011 Mineur YS, Abizaid A, Rao Y, Salas R, DiLeone RJ, Gündisch D, Diano S, De Biasi M, Horvath TL, Gao XB, Picciotto MR. Nicotine decreases food intake through activation of POMC neurons. Science (New York, N.Y.). 332: 1330-2. PMID 21659607 DOI: 10.1126/Science.1201889  0.33
2011 Wolff EF, Gao XB, Yao KV, Andrews ZB, Du H, Elsworth JD, Taylor HS. Endometrial stem cell transplantation restores dopamine production in a Parkinson's disease model. Journal of Cellular and Molecular Medicine. 15: 747-55. PMID 20406327 DOI: 10.1111/J.1582-4934.2010.01068.X  0.319
2010 Gyengesi E, Liu ZW, D'Agostino G, Gan G, Horvath TL, Gao XB, Diano S. Corticosterone regulates synaptic input organization of POMC and NPY/AgRP neurons in adult mice. Endocrinology. 151: 5395-402. PMID 20843996 DOI: 10.1210/En.2010-0681  0.423
2010 Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao XB, Horvath TL. Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11815-25. PMID 20810901 DOI: 10.1523/Jneurosci.2234-10.2010  0.462
2010 Korosi A, Shanabrough M, McClelland S, Liu ZW, Borok E, Gao XB, Horvath TL, Baram TZ. Early-life experience reduces excitation to stress-responsive hypothalamic neurons and reprograms the expression of corticotropin-releasing hormone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 703-13. PMID 20071535 DOI: 10.1523/Jneurosci.4214-09.2010  0.42
2010 Gao XB, Wang AH. Experience-dependent plasticity in hypocretin/orexin neurones: re-setting arousal threshold. Acta Physiologica (Oxford, England). 198: 251-62. PMID 19785627 DOI: 10.1111/j.1748-1716.2009.02047.x  0.446
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/Jneurosci.3890-09.2009  0.345
2009 Gao XB. Electrophysiological effects of MCH on neurons in the hypothalamus. Peptides. 30: 2025-30. PMID 19463877 DOI: 10.1016/j.peptides.2009.05.006  0.451
2008 Rao Y, Lu M, Ge F, Marsh DJ, Qian S, Wang AH, Picciotto MR, Gao XB. Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9101-10. PMID 18784290 DOI: 10.1523/JNEUROSCI.1766-08.2008  0.457
2008 Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 454: 846-51. PMID 18668043 DOI: 10.1038/Nature07181  0.463
2007 Rao Y, Liu ZW, Borok E, Rabenstein RL, Shanabrough M, Lu M, Picciotto MR, Horvath TL, Gao XB. Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons. The Journal of Clinical Investigation. 117: 4022-33. PMID 18060037 DOI: 10.1172/JCI32829  0.393
2007 Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metabolism. 5: 21-33. PMID 17189204 DOI: 10.1016/J.Cmet.2006.12.002  0.369
2007 Liu ZW, Gao XB. Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect. Journal of Neurophysiology. 97: 837-48. PMID 17093123 DOI: 10.1152/jn.00873.2006  0.397
2006 Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal of Clinical Investigation. 116: 3229-39. PMID 17060947 DOI: 10.1172/Jci29867  0.423
2005 Horvath TL, Gao XB. Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia. Cell Metabolism. 1: 279-86. PMID 16054072 DOI: 10.1016/j.cmet.2005.03.003  0.434
2003 Gao XB, Ghosh PK, van den Pol AN. Neurons synthesizing melanin-concentrating hormone identified by selective reporter gene expression after transfection in vitro: transmitter responses. Journal of Neurophysiology. 90: 3978-85. PMID 14573562 DOI: 10.1152/jn.00593.2003  0.453
2002 Li Y, Gao XB, Sakurai T, van den Pol AN. Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron. 36: 1169-81. PMID 12495630 DOI: 10.1016/S0896-6273(02)01132-7  0.359
2002 Obrietan K, Gao XB, Van Den Pol AN. Excitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism--a positive feedback circuit in developing neurons. Journal of Neurophysiology. 88: 1005-15. PMID 12163549 DOI: 10.1152/Jn.2002.88.2.1005  0.359
2002 Gao XB, van den Pol AN. Melanin-concentrating hormone depresses L-, N-, and P/Q-type voltage-dependent calcium channels in rat lateral hypothalamic neurons. The Journal of Physiology. 542: 273-86. PMID 12096069 DOI: 10.1113/jphysiol.2002.019372  0.411
2002 van den Pol AN, Ghosh PK, Liu RJ, Li Y, Aghajanian GK, Gao XB. Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus. The Journal of Physiology. 541: 169-85. PMID 12015428 DOI: 10.1113/jphysiol.2002.017426  0.429
2001 Wang YF, Gao XB, van den Pol AN. Membrane properties underlying patterns of GABA-dependent action potentials in developing mouse hypothalamic neurons. Journal of Neurophysiology. 86: 1252-65. PMID 11535674 DOI: 10.1152/Jn.2001.86.3.1252  0.353
2001 Gao XB, van den Pol AN. Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus. The Journal of Physiology. 533: 237-52. PMID 11351031 DOI: 10.1111/j.1469-7793.2001.0237b.x  0.441
2001 Van Den Pol AN, Patrylo PR, Ghosh PK, Gao XB. Lateral hypothalamus: early developmental expression and response to hypocretin (orexin). The Journal of Comparative Neurology. 433: 349-63. PMID 11298360 DOI: 10.1002/Cne.1144  0.434
2001 Gao XB, van den Pol AN. GABA, not glutamate, a primary transmitter driving action potentials in developing hypothalamic neurons. Journal of Neurophysiology. 85: 425-34. PMID 11152743 DOI: 10.1152/Jn.2001.85.1.425  0.433
2000 Gao XB, van den Pol AN. GABA release from mouse axonal growth cones. The Journal of Physiology. 523: 629-37. PMID 10718743 DOI: 10.1111/J.1469-7793.2000.T01-1-00629.X  0.347
1999 Liu QS, Patrylo PR, Gao XB, van den Pol AN. Kainate acts at presynaptic receptors to increase GABA release from hypothalamic neurons. Journal of Neurophysiology. 82: 1059-62. PMID 10444697 DOI: 10.1152/Jn.1999.82.2.1059  0.391
1999 Gao XB, van den Pol AN. Neurotrophin-3 potentiates excitatory GABAergic synaptic transmission in cultured developing hypothalamic neurones of the rat. The Journal of Physiology. 518: 81-95. PMID 10373691 DOI: 10.1111/j.1469-7793.1999.0081r.x  0.42
1998 van den Pol AN, Gao XB, Patrylo PR, Ghosh PK, Obrietan K. Glutamate inhibits GABA excitatory activity in developing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10749-61. PMID 9852609 DOI: 10.1523/Jneurosci.18-24-10749.1998  0.395
1998 van den Pol AN, Gao XB, Obrietan K, Kilduff TS, Belousov AB. Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7962-71. PMID 9742163 DOI: 10.1523/Jneurosci.18-19-07962.1998  0.391
1998 Gao XB, Chen G, van den Pol AN. GABA-dependent firing of glutamate-evoked action potentials at AMPA/kainate receptors in developing hypothalamic neurons. Journal of Neurophysiology. 79: 716-26. PMID 9463435 DOI: 10.1152/Jn.1998.79.2.716  0.37
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