| Year |
Citation |
Score |
| 2023 |
Asano M, Kajita K, Fuwa M, Kajita T, Mori I, Akahoshi N, Ishii I, Morita H. Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice. Endocrinology. PMID 36690339 DOI: 10.1210/endocr/bqad019 |
0.322 |
|
| 2020 |
Ellmers LJ, Templeton EM, Pilbrow AP, Frampton C, Ishii I, Moore PK, Bhatia M, Richards AM, Cameron VA. Hydrogen Sulfide Treatment Improves Post-Infarct Remodeling and Long-Term Cardiac Function in CSE Knockout and Wild-Type Mice. International Journal of Molecular Sciences. 21. PMID 32560137 DOI: 10.3390/Ijms21124284 |
0.316 |
|
| 2020 |
Akiyama M, Unoki T, Yoshida E, Ding Y, Yamakawa H, Shinkai Y, Ishii I, Kumagai Y. Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain. Toxicology Letters. PMID 32413476 DOI: 10.1016/J.Toxlet.2020.05.007 |
0.332 |
|
| 2020 |
Akahoshi N, Minakawa T, Miyashita M, Sugiyama U, Saito C, Takemoto R, Honda A, Kamichatani W, Kamata S, Anan Y, Ishii I. Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria. International Journal of Molecular Sciences. 21. PMID 32012740 DOI: 10.3390/Ijms21030818 |
0.35 |
|
| 2019 |
Akahoshi N, Handa H, Takemoto R, Kamata S, Yoshida M, Onaka T, Ishii I. Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase-An Animal Model of Cystathioninuria. International Journal of Molecular Sciences. 20. PMID 31319489 DOI: 10.3390/Ijms20143507 |
0.342 |
|
| 2019 |
Gaddam RR, Chambers S, Fraser R, Cogger VC, Le Couteur DG, Ishii I, Bhatia M. Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis. International Journal of Molecular Sciences. 20. PMID 31261857 DOI: 10.3390/Ijms20133191 |
0.361 |
|
| 2019 |
Akahoshi N, Yokoyama A, Nagata T, Miura A, Kamata S, Ishii I. Abnormal Amino Acid Profiles of Blood and Cerebrospinal Fluid from Cystathionine β-Synthase-Deficient Mice, an Animal Model of Homocystinuria. Biological & Pharmaceutical Bulletin. 42: 1054-1057. PMID 31155583 DOI: 10.1248/Bpb.B19-00127 |
0.338 |
|
| 2019 |
Akahoshi N, Anan Y, Hashimoto Y, Tokoro N, Mizuno R, Hayashi S, Yamamoto S, Shimada KI, Kamata S, Ishii I. Dietary selenium deficiency or selenomethionine excess drastically alters organ selenium contents without altering the expression of most selenoproteins in mice. The Journal of Nutritional Biochemistry. 69: 120-129. PMID 31078905 DOI: 10.1016/J.Jnutbio.2019.03.020 |
0.319 |
|
| 2018 |
Kamata S, Yamamoto J, Ohtani H, Tosaka Y, Yoshikawa S, Akahoshi N, Ishii I. 2D DIGE proteomic analysis reveals fasting-induced protein remodeling through organ-specific transcription factor(s) in mice. Febs Open Bio. 8: 1524-1543. PMID 30186752 DOI: 10.1002/2211-5463.12497 |
0.329 |
|
| 2017 |
Castelblanco M, Lugrin J, Ehirchiou D, Nasi S, Ishii I, So A, Martinon F, Busso N. Hydrogen sulfide inhibits the NLRP3 inflammasome and reduces cytokine production both in vitro and in a mouse model of inflammation. The Journal of Biological Chemistry. PMID 29279328 DOI: 10.1074/Jbc.M117.806869 |
0.32 |
|
| 2016 |
Gaddam RR, Fraser R, Badiei A, Chambers S, Cogger VC, Le Couteur DG, Ishii I, Bhatia M. Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis. Plos One. 11: e0160521. PMID 27518439 DOI: 10.1371/Journal.Pone.0160521 |
0.337 |
|
| 2016 |
Kitada Y, Kajita K, Taguchi K, Mori I, Yamauchi M, Ikeda T, Kawashima M, Asano M, Kajita T, Ishizuka T, Banno Y, Kojima I, Chun J, Kamata S, Ishii I, et al. Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice. Endocrinology. en20151768. PMID 26943364 DOI: 10.1210/En.2015-1768 |
0.549 |
|
| 2015 |
Ishii I, Kamata S, Hagiya Y, Abiko Y, Kasahara T, Kumagai Y. Protective effects of hydrogen sulfide anions against acetaminophen-induced hepatotoxicity in mice. The Journal of Toxicological Sciences. 40: 837-41. PMID 26558465 DOI: 10.2131/Jts.40.837 |
0.342 |
|
| 2015 |
Kamata S, Akahoshi N, Ishii I. 2D DIGE proteomic analysis highlights delayed postnatal repression of α-fetoprotein expression in homocystinuria model mice. Febs Open Bio. 5: 535-41. PMID 26199862 DOI: 10.1016/J.Fob.2015.06.008 |
0.336 |
|
| 2015 |
Abiko Y, Yoshida E, Ishii I, Fukuto JM, Akaike T, Kumagai Y. Involvement of Reactive Persulfides in Biological Bismethylmercury Sulfide Formation. Chemical Research in Toxicology. 28: 1301-6. PMID 25874357 DOI: 10.1021/Acs.Chemrestox.5B00101 |
0.321 |
|
| 2015 |
Nakano S, Ishii I, Shinmura K, Tamaki K, Hishiki T, Akahoshi N, Ida T, Nakanishi T, Kamata S, Kumagai Y, Akaike T, Fukuda K, Sano M, Suematsu M. Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions. Journal of Molecular Medicine (Berlin, Germany). PMID 25740079 DOI: 10.1007/S00109-015-1271-5 |
0.341 |
|
| 2015 |
Shinmura K, Tamaki K, Ito K, Yan X, Yamamoto T, Katsumata Y, Matsuhashi T, Sano M, Fukuda K, Suematsu M, Ishii I. Indispensable role of endothelial nitric oxide synthase in caloric restriction-induced cardioprotection against ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 308: H894-903. PMID 25681423 DOI: 10.1152/Ajpheart.00333.2014 |
0.346 |
|
| 2015 |
Hagiya Y, Kamata S, Mitsuoka S, Okada N, Yoshida S, Yamamoto J, Ohkubo R, Abiko Y, Yamada H, Akahoshi N, Kasahara T, Kumagai Y, Ishii I. Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice. Toxicology and Applied Pharmacology. 282: 195-206. PMID 25499718 DOI: 10.1016/J.Taap.2014.11.015 |
0.354 |
|
| 2014 |
Akahoshi N, Kamata S, Kubota M, Hishiki T, Nagahata Y, Matsuura T, Yamazaki C, Yoshida Y, Yamada H, Ishizaki Y, Suematsu M, Kasahara T, Ishii I. Neutral aminoaciduria in cystathionine β-synthase-deficient mice; an animal model of homocystinuria. American Journal of Physiology. Renal Physiology. 306: F1462-76. PMID 24761004 DOI: 10.1152/Ajprenal.00623.2013 |
0.33 |
|
| 2013 |
Okamoto M, Yamaoka M, Takei M, Ando T, Taniguchi S, Ishii I, Tohya K, Ishizaki T, Niki I, Kimura T. Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes. Biochemical and Biophysical Research Communications. 442: 227-33. PMID 24246677 DOI: 10.1016/J.Bbrc.2013.11.023 |
0.323 |
|
| 2013 |
Ang AD, Rivers-Auty J, Hegde A, Ishii I, Bhatia M. The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G712-21. PMID 24008358 DOI: 10.1152/Ajpgi.00044.2013 |
0.364 |
|
| 2012 |
Yamada H, Akahoshi N, Kamata S, Hagiya Y, Hishiki T, Nagahata Y, Matsuura T, Takano N, Mori M, Ishizaki Y, Izumi T, Kumagai Y, Kasahara T, Suematsu M, Ishii I. Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria. Free Radical Biology & Medicine. 52: 1716-26. PMID 22387178 DOI: 10.1016/J.Freeradbiomed.2012.02.033 |
0.307 |
|
| 2012 |
Morikawa T, Kajimura M, Nakamura T, Hishiki T, Nakanishi T, Yukutake Y, Nagahata Y, Ishikawa M, Hattori K, Takenouchi T, Takahashi T, Ishii I, Matsubara K, Kabe Y, Uchiyama S, et al. Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway. Proceedings of the National Academy of Sciences of the United States of America. 109: 1293-8. PMID 22232681 DOI: 10.1073/Pnas.1119658109 |
0.312 |
|
| 2012 |
Taniguchi S, Kimura T, Umeki T, Kimura Y, Kimura H, Ishii I, Itoh N, Naito Y, Yamamoto H, Niki I. Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell. Molecular and Cellular Endocrinology. 350: 31-8. PMID 22133746 DOI: 10.1016/J.Mce.2011.11.016 |
0.527 |
|
| 2011 |
Akahoshi N, Ishizaki Y, Yasuda H, Murashima YL, Shinba T, Goto K, Himi T, Chun J, Ishii I. Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2. Epilepsy & Behavior : E&B. 22: 659-65. PMID 22019019 DOI: 10.1016/J.Yebeh.2011.09.002 |
0.574 |
|
| 2010 |
Ishii I, Akahoshi N, Yamada H, Nakano S, Izumi T, Suematsu M. Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury. The Journal of Biological Chemistry. 285: 26358-68. PMID 20566639 DOI: 10.1074/Jbc.M110.147439 |
0.321 |
|
| 2010 |
Imasawa T, Koike K, Ishii I, Chun J, Yatomi Y. Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells. Biochemical and Biophysical Research Communications. 392: 207-11. PMID 20060809 DOI: 10.1016/J.Bbrc.2010.01.016 |
0.599 |
|
| 2010 |
Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, ... ... Ishii I, et al. S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species. Cardiovascular Research. 85: 484-93. PMID 19755413 DOI: 10.1093/Cvr/Cvp312 |
0.603 |
|
| 2009 |
Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Iitsuka S, Fujita R, Omata M, Chun J, Yatomi Y. Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. Journal of Lipid Research. 50: 556-64. PMID 18955732 DOI: 10.1194/Jlr.M800496-Jlr200 |
0.58 |
|
| 2007 |
Akahoshi N, Murashima YL, Himi T, Ishizaki Y, Ishii I. Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures. Neuroscience Letters. 429: 136-41. PMID 17997037 DOI: 10.1016/J.Neulet.2007.10.007 |
0.337 |
|
| 2007 |
Means CK, Xiao CY, Li Z, Zhang T, Omens JH, Ishii I, Chun J, Brown JH. Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2944-51. PMID 17293497 DOI: 10.1152/Ajpheart.01331.2006 |
0.643 |
|
| 2007 |
Akahoshi N, Murashima YL, Himi T, Ishizaki Y, Ishii I. GeneChip analysis of the neocortical and hippocampal gene expression in kainate- and nicotine-injected mice Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.1397 |
0.308 |
|
| 2006 |
Schicho R, Krueger D, Zeller F, Von Weyhern CW, Frieling T, Kimura H, Ishii I, De Giorgio R, Campi B, Schemann M. Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. Gastroenterology. 131: 1542-52. PMID 17101327 DOI: 10.1053/J.Gastro.2006.08.035 |
0.315 |
|
| 2006 |
Akahoshi N, Izumi T, Ishizaki Y, Ishii I. Differential induction of cystathionine gamma-lyase in the livers and kidneys of mouse dams during gestation and lactation. Biological & Pharmaceutical Bulletin. 29: 1799-802. PMID 16946488 DOI: 10.1248/Bpb.29.1799 |
0.307 |
|
| 2005 |
Goparaju SK, Jolly PS, Watterson KR, Bektas M, Alvarez S, Sarkar S, Mel L, Ishii I, Chun J, Milstien S, Spiegel S. The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation. Molecular and Cellular Biology. 25: 4237-49. PMID 15870293 DOI: 10.1128/Mcb.25.10.4237-4249.2005 |
0.628 |
|
| 2004 |
Namekata K, Enokido Y, Ishii I, Nagai Y, Harada T, Kimura H. Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia. The Journal of Biological Chemistry. 279: 52961-9. PMID 15466479 DOI: 10.1074/Jbc.M406820200 |
0.332 |
|
| 2004 |
Ishii I, Fukushima N, Ye X, Chun J. Lysophospholipid receptors: signaling and biology. Annual Review of Biochemistry. 73: 321-54. PMID 15189145 DOI: 10.1146/Annurev.Biochem.73.011303.073731 |
0.798 |
|
| 2004 |
Ishii I, Akahoshi N, Yu XN, Kobayashi Y, Namekata K, Komaki G, Kimura H. Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. The Biochemical Journal. 381: 113-23. PMID 15038791 DOI: 10.1042/Bj20040243 |
0.32 |
|
| 2004 |
Nofer JR, van der Giet M, Tölle M, Wolinska I, von Wnuck Lipinski K, Baba HA, Tietge UJ, Gödecke A, Ishii I, Kleuser B, Schäfers M, Fobker M, Zidek W, Assmann G, Chun J, et al. HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. The Journal of Clinical Investigation. 113: 569-81. PMID 14966566 DOI: 10.1172/Jci18004 |
0.591 |
|
| 2004 |
Baudhuin LM, Jiang Y, Zaslavsky A, Ishii I, Chun J, Xu Y. S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 341-3. PMID 14657000 DOI: 10.1096/Fj.03-0302Fje |
0.628 |
|
| 2003 |
Olivera A, Rosenfeldt HM, Bektas M, Wang F, Ishii I, Chun J, Milstien S, Spiegel S. Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. The Journal of Biological Chemistry. 278: 46452-60. PMID 12963721 DOI: 10.1074/Jbc.M308749200 |
0.64 |
|
| 2003 |
Liu H, Toman RE, Goparaju SK, Maceyka M, Nava VE, Sankala H, Payne SG, Bektas M, Ishii I, Chun J, Milstien S, Spiegel S. Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis. The Journal of Biological Chemistry. 278: 40330-6. PMID 12835323 DOI: 10.1074/Jbc.M304455200 |
0.533 |
|
| 2002 |
Ye X, Ishii I, Kingsbury MA, Chun J. Lysophosphatidic acid as a novel cell survival/apoptotic factor. Biochimica Et Biophysica Acta. 1585: 108-13. PMID 12531543 DOI: 10.1016/S1388-1981(02)00330-X |
0.769 |
|
| 2002 |
Contos JJ, Ishii I, Fukushima N, Kingsbury MA, Ye X, Kawamura S, Brown JH, Chun J. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Molecular and Cellular Biology. 22: 6921-9. PMID 12215548 DOI: 10.1128/Mcb.22.19.6921-6929.2002 |
0.797 |
|
| 2002 |
Fukushima N, Ishii I, Habara Y, Allen CB, Chun J. Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rho. Molecular Biology of the Cell. 13: 2692-705. PMID 12181339 DOI: 10.1091/Mbc.01-09-0465 |
0.703 |
|
| 2002 |
Yang AH, Ishii I, Chun J. In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice. Biochimica Et Biophysica Acta. 1582: 197-203. PMID 12069829 DOI: 10.1016/S1388-1981(02)00172-5 |
0.745 |
|
| 2002 |
Ishii I, Ye X, Friedman B, Kawamura S, Contos JJ, Kingsbury MA, Yang AH, Zhang G, Brown JH, Chun J. Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. The Journal of Biological Chemistry. 277: 25152-9. PMID 12006579 DOI: 10.1074/Jbc.M200137200 |
0.755 |
|
| 2002 |
Ishii I, Chun J. Anandamide-induced neuroblastoma cell rounding via the CBI cannabinoid receptors Neuroreport. 13: 593-596. PMID 11973452 DOI: 10.1097/00001756-200204160-00011 |
0.611 |
|
| 2001 |
Ishii I, Friedman B, Ye X, Kawamura S, McGiffert C, Contos JJ, Kingsbury MA, Zhang G, Brown JH, Chun J. Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. The Journal of Biological Chemistry. 276: 33697-704. PMID 11443127 DOI: 10.1074/Jbc.M104441200 |
0.695 |
|
| 2001 |
Kimura Y, Schmitt A, Fukushima N, Ishii I, Kimura H, Nebreda AR, Chun J. Two novel Xenopus homologs of mammalian LP(A1)/EDG-2 function as lysophosphatidic acid receptors in Xenopus oocytes and mammalian cells. The Journal of Biological Chemistry. 276: 15208-15. PMID 11278944 DOI: 10.1074/Jbc.M011588200 |
0.734 |
|
| 2001 |
Contos JJ, Ishii I, Chun J. Lysophosphatidic acid receptors. Molecular Pharmacology. 58: 1188-96. PMID 11093753 DOI: 10.1124/Mol.58.6.1188 |
0.635 |
|
| 2000 |
Ishii I, Contos JJ, Fukushima N, Chun J. Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Molecular Pharmacology. 58: 895-902. PMID 11040035 DOI: 10.1124/Mol.58.5.895 |
0.741 |
|
| 2000 |
Chun J, Weiner JA, Fukushima N, Contos JJ, Zhang G, Kimura Y, Dubin A, Ishii I, Hecht JH, Akita C, Kaushal D. Neurobiology of receptor-mediated lysophospholipid signaling. From the first lysophospholipid receptor to roles in nervous system function and development. Annals of the New York Academy of Sciences. 905: 110-7. PMID 10818447 DOI: 10.1111/J.1749-6632.2000.Tb06543.X |
0.724 |
|
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