| Year |
Citation |
Score |
| 2023 |
Chitraju C, Fischer AW, Ambaw YA, Wang K, Yuan B, Hui S, Walther TC, Farese RV. Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity. Elife. 12. PMID 37782317 DOI: 10.7554/eLife.88049 |
0.593 |
|
| 2023 |
Chung J, Park J, Lai ZW, Lambert TJ, Richards RC, Zhang J, Walther TC, Farese RV. The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets. Nature Cell Biology. PMID 37443287 DOI: 10.1038/s41556-023-01178-w |
0.658 |
|
| 2023 |
Wang K, Lee CW, Sui X, Kim S, Wang S, Higgs AB, Baublis AJ, Voth GA, Liao M, Walther TC, Farese RV. The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification. Nature Communications. 14: 3533. PMID 37316513 DOI: 10.1038/s41467-023-38932-5 |
0.617 |
|
| 2023 |
Sui X, Wang K, Song K, Xu C, Song J, Lee CW, Liao M, Farese RV, Walther TC. Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis. Nature Communications. 14: 3100. PMID 37248213 DOI: 10.1038/s41467-023-38934-3 |
0.594 |
|
| 2023 |
Walther TC, Kim S, Arlt H, Voth GA, Farese RV. Structure and function of lipid droplet assembly complexes. Current Opinion in Structural Biology. 80: 102606. PMID 37150040 DOI: 10.1016/j.sbi.2023.102606 |
0.7 |
|
| 2023 |
Bond LM, Ibrahim A, Lai ZW, Walzem RL, Bronson RT, Ilkayeva OR, Walther TC, Farese RV. Fitm2 is required for ER homeostasis and normal function of murine liver. The Journal of Biological Chemistry. 103022. PMID 36805337 DOI: 10.1016/j.jbc.2023.103022 |
0.619 |
|
| 2022 |
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, ... ... Walther TC, et al. Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nature Communications. 13: 5924. PMID 36207292 DOI: 10.1038/s41467-022-33500-9 |
0.679 |
|
| 2022 |
Farese RV, Walther TC. Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum. Cold Spring Harbor Perspectives in Biology. PMID 36096640 DOI: 10.1101/cshperspect.a041246 |
0.656 |
|
| 2022 |
Song J, Mizrak A, Lee CW, Cicconet M, Lai ZW, Tang WC, Lu CH, Mohr SE, Farese RV, Walther TC. Identification of two pathways mediating protein targeting from ER to lipid droplets. Nature Cell Biology. PMID 36050470 DOI: 10.1038/s41556-022-00974-0 |
0.681 |
|
| 2022 |
Kim S, Chung J, Arlt H, Pak AJ, Farese RV, Walther TC, Voth GA. Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane. Elife. 11. PMID 35583926 DOI: 10.7554/eLife.75808 |
0.65 |
|
| 2022 |
Arlt H, Sui X, Folger B, Adams C, Chen X, Remme R, Hamprecht FA, DiMaio F, Liao M, Goodman JM, Farese RV, Walther TC. Seipin forms a flexible cage at lipid droplet formation sites. Nature Structural & Molecular Biology. PMID 35210614 DOI: 10.1038/s41594-021-00718-y |
0.62 |
|
| 2022 |
Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer N, Song J, Kuruvilla L, Chitraju C, Boland S, Jang DK, von Grotthuss M, Costanzo MC, Rydén M, Olzmann JA, Flannick J, Burtt NP, ... ... Walther TC, et al. The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology. Developmental Cell. 57: 387-397.e4. PMID 35134345 DOI: 10.1016/j.devcel.2022.01.003 |
0.828 |
|
| 2022 |
Kim S, Li C, Farese RV, Walther TC, Voth GA. Key Factors Governing Initial Stages of Lipid Droplet Formation. The Journal of Physical Chemistry. B. PMID 34990551 DOI: 10.1021/acs.jpcb.1c09683 |
0.664 |
|
| 2021 |
Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, ... Walther TC, et al. Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues. Nature. PMID 34732896 DOI: 10.1038/s41586-021-04132-8 |
0.523 |
|
| 2021 |
Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, ... Walther TC, et al. An open-access volume electron microscopy atlas of whole cells and tissues. Nature. PMID 34616045 DOI: 10.1038/s41586-021-03992-4 |
0.553 |
|
| 2021 |
Olarte MJ, Swanson JMJ, Walther TC, Farese RV. The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting. Trends in Biochemical Sciences. PMID 34583871 DOI: 10.1016/j.tibs.2021.08.007 |
0.702 |
|
| 2021 |
Kumar S, Chitraju C, Farese R, Walther T, Burd CG. Conditional targeting of phosphatidylserine decarboxylase to lipid droplets. Biology Open. PMID 33593792 DOI: 10.1242/bio.058516 |
0.701 |
|
| 2021 |
Farese RV, Walther TC. The power of two: lessons from a scientific partnership. The Journal of Clinical Investigation. 131. PMID 33463550 DOI: 10.1172/JCI145966 |
0.493 |
|
| 2020 |
Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai ZW, Farese RV, Walther TC. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Reports. 33: 108378. PMID 33176155 DOI: 10.1016/j.celrep.2020.108378 |
0.761 |
|
| 2020 |
Chitraju C, Fischer AW, Farese RV, Walther TC. Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis. Cell Reports. 33: 108348. PMID 33147469 DOI: 10.1016/j.celrep.2020.108348 |
0.605 |
|
| 2020 |
Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. The Journal of Cell Biology. 219. PMID 32915949 DOI: 10.1083/Jcb.202006111 |
0.813 |
|
| 2020 |
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7 |
0.6 |
|
| 2020 |
Olarte MJ, Kim S, Sharp ME, Swanson JMJ, Farese RV, Walther TC. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting. Developmental Cell. PMID 32730754 DOI: 10.1016/J.Devcel.2020.07.001 |
0.711 |
|
| 2020 |
Sui X, Wang K, Gluchowski NL, Elliott SD, Liao M, Walther TC, Farese RV. Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature. 581: 323-328. PMID 32433611 DOI: 10.1038/S41586-020-2289-6 |
0.675 |
|
| 2020 |
Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant mice, a model of motor neuron degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345721 DOI: 10.1073/Pnas.1913956117 |
0.766 |
|
| 2020 |
Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Molecular Cell. PMID 32023484 DOI: 10.1016/J.Molcel.2020.01.014 |
0.797 |
|
| 2019 |
Chung J, Wu X, Lambert TJ, Lai ZW, Walther TC, Farese RV. LDAF1 and Seipin Form a Lipid Droplet Assembly Complex. Developmental Cell. PMID 31708432 DOI: 10.1016/J.Devcel.2019.10.006 |
0.706 |
|
| 2019 |
Walther TC, Farese RV. Un-phased: Lipid Droplets Modulate the Bioavailability of Antibiotics. Developmental Cell. 50: 530-532. PMID 31505174 DOI: 10.1016/J.Devcel.2019.08.009 |
0.634 |
|
| 2019 |
Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV, Walther TC. Hepatocyte Deletion of Triglyceride-Synthesis Enzyme DGAT2 Reduces Steatosis without Increasing Inflammation or Fibrosis. Hepatology (Baltimore, Md.). PMID 31081165 DOI: 10.1002/Hep.30765 |
0.769 |
|
| 2019 |
Chitraju C, Walther TC, Farese RV. The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes. Journal of Lipid Research. 60: 1112-1120. PMID 30936184 DOI: 10.1194/Jlr.M093112 |
0.624 |
|
| 2019 |
Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/J.Molcel.2019.01.036 |
0.661 |
|
| 2018 |
Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 7. PMID 30582518 DOI: 10.7554/Elife.43036 |
0.58 |
|
| 2018 |
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, ... ... Walther TC, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028 |
0.731 |
|
| 2018 |
Krahmer N, Najafi B, Schueder F, Quagliarini F, Steger M, Seitz S, Kasper R, Salinas F, Cox J, Uhlenhaut NH, Walther TC, Jungmann R, Zeigerer A, Borner GHH, Mann M. Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Developmental Cell. 47: 205-221.e7. PMID 30352176 DOI: 10.1016/J.Devcel.2018.09.017 |
0.799 |
|
| 2018 |
Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV, Walther TC. Cryo-electron microscopy structure of the lipid droplet-formation protein seipin. The Journal of Cell Biology. PMID 30327422 DOI: 10.1083/Jcb.201809067 |
0.716 |
|
| 2018 |
Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV. Progranulin in the hematopoietic compartment protects mice from atherosclerosis. Atherosclerosis. 277: 145-154. PMID 30212683 DOI: 10.1016/J.Atherosclerosis.2018.08.042 |
0.676 |
|
| 2018 |
Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, et al. Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop. Circulation. 138: 305-315. PMID 30012703 DOI: 10.1161/Circulationaha.118.033704 |
0.329 |
|
| 2018 |
Jayson CBK, Arlt H, Fischer AW, Lai ZW, Farese RV, Walther TC. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Molecular Biology of the Cell. mbcE18050282. PMID 29949452 DOI: 10.1091/Mbc.E18-05-0282 |
0.722 |
|
| 2018 |
Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511098 DOI: 10.1073/Pnas.1722344115 |
0.685 |
|
| 2018 |
Li Z, Lai ZW, Christiano R, Gazos-Lopes F, Walther TC, Farese RV. Global Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity. Molecular & Cellular Proteomics : McP. PMID 29414761 DOI: 10.1074/Mcp.Ra117.000560 |
0.584 |
|
| 2018 |
Prévost C, Sharp ME, Kory N, Lin Q, Voth GA, Farese RV, Walther TC. Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets. Developmental Cell. 44: 73-86.e4. PMID 29316443 DOI: 10.1016/J.Devcel.2017.12.011 |
0.837 |
|
| 2018 |
Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. Author response: The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 Elife. DOI: 10.7554/Elife.43036.025 |
0.56 |
|
| 2018 |
Sharp ME, Prevost C, Olarte M, Farese RV, Walther TC, Voth GA. Mechanism of Protein Targeting to Lipid Droplets Biophysical Journal. 114: 70a. DOI: 10.1016/J.Bpj.2017.11.431 |
0.482 |
|
| 2017 |
Inloes JM, Kiosses WB, Wang H, Walther TC, Farese RV, Cravatt BF. Functional Contribution of the Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2 to the Formation and Content of Lipid Droplets. Biochemistry. PMID 29278326 DOI: 10.1021/Acs.Biochem.7B01028 |
0.694 |
|
| 2017 |
Walther TC, Chung J, Farese RV. Lipid Droplet Biogenesis. Annual Review of Cell and Developmental Biology. PMID 28793795 DOI: 10.1146/Annurev-Cellbio-100616-060608 |
0.717 |
|
| 2017 |
Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV. Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis. Cell Metabolism. 26: 407-418.e3. PMID 28768178 DOI: 10.1016/J.Cmet.2017.07.012 |
0.774 |
|
| 2017 |
Christiano R, Kolev NG, Shi H, Ullu E, Walther TC, Tschudi C. The proteome and transcriptome of the infectious metacyclic form of Trypanosoma brucei define quiescent cells primed for mammalian invasion. Molecular Microbiology. PMID 28742275 DOI: 10.1111/Mmi.13754 |
0.362 |
|
| 2017 |
Gluchowski NL, Becuwe M, Walther TC, Farese RV. Lipid droplets and liver disease: from basic biology to clinical implications. Nature Reviews. Gastroenterology & Hepatology. 14: 343-355. PMID 28428634 DOI: 10.1038/Nrgastro.2017.32 |
0.682 |
|
| 2017 |
Gluchowski NL, Chitraju C, Picoraro JA, Mejhert N, Pinto S, Xin W, Kamin DS, Winter HS, Chung WK, Walther TC, Farese RV. Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea. Journal of Lipid Research. PMID 28373485 DOI: 10.1194/Jlr.P075119 |
0.757 |
|
| 2016 |
Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Fröhlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV, Walther TC. Mice Lacking Lipid Droplet-Associated Hydrolase, a Gene Linked to Human Prostate Cancer, Have Normal Cholesterol Ester Metabolism. Journal of Lipid Research. PMID 27836991 DOI: 10.1194/Jlr.M072538 |
0.812 |
|
| 2016 |
Fröhlich F, Olson DK, Christiano R, Farese RV, Walther TC. Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion. Proteomics. 16: 2759-2763. PMID 27717283 DOI: 10.1002/Pmic.201600269 |
0.694 |
|
| 2016 |
Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Walther TC, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 5. PMID 27564575 DOI: 10.7554/Elife.16582 |
0.819 |
|
| 2016 |
Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets. Trends in Cell Biology. 26: 535-546. PMID 26995697 DOI: 10.1016/J.Tcb.2016.02.007 |
0.837 |
|
| 2016 |
Olson DK, Fröhlich F, Farese RV, Walther TC. Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis. Biochimica Et Biophysica Acta. 1861: 784-92. PMID 26747648 DOI: 10.1016/J.Bbalip.2015.12.021 |
0.432 |
|
| 2016 |
Farese RV, Walther TC. Lipid droplets go nuclear. The Journal of Cell Biology. 212: 7-8. PMID 26728852 DOI: 10.1083/Jcb.201512056 |
0.687 |
|
| 2016 |
Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte M, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Walther TC, et al. Author response: Seipin is required for converting nascent to mature lipid droplets Elife. DOI: 10.7554/Elife.16582.033 |
0.703 |
|
| 2016 |
Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets Trends in Cell Biology. 26: 535-546. DOI: 10.1016/j.tcb.2016.02.007 |
0.846 |
|
| 2015 |
Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, et al. The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Nature Cell Biology. PMID 26571211 DOI: 10.1038/Ncb3271 |
0.378 |
|
| 2015 |
Fröhlich F, Petit C, Kory N, Christiano R, Hannibal-Bach HK, Graham M, Liu X, Ejsing CS, Farese RV, Walther TC. The GARP complex is required for cellular sphingolipid homeostasis. Elife. 4. PMID 26357016 DOI: 10.7554/Elife.08712 |
0.816 |
|
| 2015 |
Siragusa M, Fröhlich F, Park EJ, Schleicher M, Walther TC, Sessa WC. Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation. Science Signaling. 8: ra81. PMID 26286023 DOI: 10.1126/Scisignal.Aaa2819 |
0.309 |
|
| 2015 |
Kory N, Thiam AR, Farese RV, Walther TC. Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Developmental Cell. 34: 351-63. PMID 26212136 DOI: 10.1016/J.Devcel.2015.06.007 |
0.825 |
|
| 2015 |
Shibuya A, Margulis N, Christiano R, Walther TC, Barlowe C. The Erv41-Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins. The Journal of Cell Biology. 208: 197-209. PMID 25583996 DOI: 10.1083/Jcb.201408024 |
0.389 |
|
| 2015 |
Olson DK, Fröhlich F, Christiano R, Hannibal-Bach HK, Ejsing CS, Walther TC. Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids. The Journal of Biological Chemistry. 290: 4238-47. PMID 25519905 DOI: 10.1074/Jbc.M114.629279 |
0.422 |
|
| 2015 |
Fröhlich F, Petit C, Kory N, Christiano R, Hannibal-Bach H, Graham M, Liu X, Ejsing CS, Farese RV, Walther TC. Author response: The GARP complex is required for cellular sphingolipid homeostasis Elife. DOI: 10.7554/Elife.08712.023 |
0.734 |
|
| 2015 |
Olson DK, Fröhlich F, Farese RV, Walther TC. Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. DOI: 10.1016/j.bbalip.2015.12.021 |
0.571 |
|
| 2014 |
Christiano R, Nagaraj N, Fröhlich F, Walther TC. Global proteome turnover analyses of the Yeasts S. cerevisiae and S. pombe. Cell Reports. 9: 1959-65. PMID 25466257 DOI: 10.1016/J.Celrep.2014.10.065 |
0.384 |
|
| 2014 |
Fröhlich F, Christiano R, Olson DK, Alcazar-Roman A, DeCamilli P, Walther TC. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Molecular Biology of the Cell. 25: 2797-806. PMID 25057013 DOI: 10.1091/Mbc.E13-11-0639 |
0.379 |
|
| 2014 |
Payne F, Lim K, Girousse A, Brown RJ, Kory N, Robbins A, Xue Y, Sleigh A, Cochran E, Adams C, Borman AD, Russel-Jones D, Gorden P, Semple RK, Saudek V, ... ... Walther TC, et al. Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease Proceedings of the National Academy of Sciences of the United States of America. 111: 8901-8906. PMID 24889630 DOI: 10.1073/Pnas.1408523111 |
0.774 |
|
| 2014 |
Currie E, Guo X, Christiano R, Chitraju C, Kory N, Harrison K, Haas J, Walther TC, Farese RV. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. Journal of Lipid Research. 55: 1465-1477. PMID 24868093 DOI: 10.1194/Jlr.M050229 |
0.831 |
|
| 2014 |
Wilfling F, Haas JT, Walther TC, Farese RV. Lipid droplet biogenesis. Current Opinion in Cell Biology. 29: 39-45. PMID 24736091 DOI: 10.1016/J.Ceb.2014.03.008 |
0.834 |
|
| 2014 |
Wilfling F, Thiam AR, Olarte MJ, Wang J, Beck R, Gould TJ, Allgeyer ES, Pincet F, Bewersdorf J, Farese RV, Walther TC. Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting. Elife. 3: e01607. PMID 24497546 DOI: 10.7554/Elife.01607 |
0.847 |
|
| 2014 |
Harrison MS, Hung CS, Liu TT, Christiano R, Walther TC, Burd CG. A mechanism for retromer endosomal coat complex assembly with cargo. Proceedings of the National Academy of Sciences of the United States of America. 111: 267-72. PMID 24344282 DOI: 10.1073/Pnas.1316482111 |
0.43 |
|
| 2013 |
Thiam AR, Farese RV, Walther TC. The biophysics and cell biology of lipid droplets. Nature Reviews. Molecular Cell Biology. 14: 775-86. PMID 24220094 DOI: 10.1038/Nrm3699 |
0.807 |
|
| 2013 |
Thiam AR, Antonny B, Wang J, Delacotte J, Wilfling F, Walther TC, Beck R, Rothman JE, Pincet F. COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. Proceedings of the National Academy of Sciences of the United States of America. 110: 13244-9. PMID 23901109 DOI: 10.1073/Pnas.1307685110 |
0.835 |
|
| 2013 |
Currie E, Schulze A, Zechner R, Walther TC, Farese RV. Cellular fatty acid metabolism and cancer. Cell Metabolism. 18: 153-61. PMID 23791484 DOI: 10.1016/J.Cmet.2013.05.017 |
0.641 |
|
| 2013 |
Krahmer N, Farese RV, Walther TC. Balancing the fat: Lipid droplets and human disease Embo Molecular Medicine. 5: 905-915. PMID 23740690 DOI: 10.1002/Emmm.201100671 |
0.823 |
|
| 2013 |
Fröhlich F, Christiano R, Walther TC. Native SILAC: metabolic labeling of proteins in prototroph microorganisms based on lysine synthesis regulation. Molecular & Cellular Proteomics : McP. 12: 1995-2005. PMID 23592334 DOI: 10.1074/Mcp.M112.025742 |
0.349 |
|
| 2013 |
Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV, ... Walther TC, et al. Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Developmental Cell. 24: 384-99. PMID 23415954 DOI: 10.1016/J.Devcel.2013.01.013 |
0.818 |
|
| 2013 |
Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/Jbc.M112.441949 |
0.712 |
|
| 2013 |
Krahmer N, Hilger M, Kory N, Wilfling F, Stoehr G, Mann M, Farese RV, Walther TC. Protein correlation profiles identify lipid droplet proteins with high confidence. Molecular & Cellular Proteomics : McP. 12: 1115-26. PMID 23319140 DOI: 10.1074/Mcp.M112.020230 |
0.812 |
|
| 2013 |
Wilfling F, Thiam AR, Olarte M, Wang J, Beck R, Gould TJ, Allgeyer ES, Pincet F, Bewersdorf J, Farese RV, Walther TC. Author response: Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting Elife. DOI: 10.7554/Elife.01607.020 |
0.826 |
|
| 2012 |
Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV. DGAT1 mutation is linked to a congenital diarrheal disorder. The Journal of Clinical Investigation. 122: 4680-4. PMID 23114594 DOI: 10.1172/Jci64873 |
0.597 |
|
| 2012 |
Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P. Seg1 controls eisosome assembly and shape. The Journal of Cell Biology. 198: 405-20. PMID 22869600 DOI: 10.1083/Jcb.201202097 |
0.807 |
|
| 2012 |
Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 11: 1510-22. PMID 22865919 DOI: 10.1074/Mcp.M112.017251 |
0.392 |
|
| 2012 |
Roczniak-Ferguson A, Petit CS, Froehlich F, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Science Signaling. 5: ra42. PMID 22692423 DOI: 10.1126/Scisignal.2002790 |
0.679 |
|
| 2012 |
Farese RV, Zechner R, Newgard CB, Walther TC. The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance Cell Metabolism. 15: 570-573. PMID 22560209 DOI: 10.1016/J.Cmet.2012.03.004 |
0.564 |
|
| 2012 |
Walther TC, Farese RV. Lipid droplets and cellular lipid metabolism Annual Review of Biochemistry. 81: 687-714. PMID 22524315 DOI: 10.1146/Annurev-Biochem-061009-102430 |
0.722 |
|
| 2012 |
Berchtold D, Piccolis M, Chiaruttini N, Riezman I, Riezman H, Roux A, Walther TC, Loewith R. Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. Nature Cell Biology. 14: 542-7. PMID 22504275 DOI: 10.1038/Ncb2480 |
0.446 |
|
| 2012 |
Walther T. Tobias Walther: floating ideas on lipids. Interview by Caitlin Sedwick. The Journal of Cell Biology. 196: 182-3. PMID 22270913 DOI: 10.1083/jcb.1962pi |
0.325 |
|
| 2012 |
Ziółkowska NE, Christiano R, Walther TC. Organized living: formation mechanisms and functions of plasma membrane domains in yeast. Trends in Cell Biology. 22: 151-8. PMID 22245053 DOI: 10.1016/J.Tcb.2011.12.002 |
0.477 |
|
| 2011 |
Karotki L, Huiskonen JT, Stefan CJ, Ziółkowska NE, Roth R, Surma MA, Krogan NJ, Emr SD, Heuser J, Grünewald K, Walther TC. Eisosome proteins assemble into a membrane scaffold. The Journal of Cell Biology. 195: 889-902. PMID 22123866 DOI: 10.1083/Jcb.201104040 |
0.441 |
|
| 2011 |
Krahmer N, Guo Y, Wilfling F, Hilger M, Lingrell S, Heger K, Newman HW, Schmidt-Supprian M, Vance DE, Mann M, Farese RV, Walther TC. Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metabolism. 14: 504-15. PMID 21982710 DOI: 10.1016/J.Cmet.2011.07.013 |
0.815 |
|
| 2011 |
Fei W, Shui G, Zhang Y, Krahmer N, Ferguson C, Kapterian TS, Lin RC, Dawes IW, Brown AJ, Li P, Huang X, Parton RG, Wenk MR, Walther TC, Yang H. A role for phosphatidic acid in the formation of "supersized" lipid droplets. Plos Genetics. 7: e1002201. PMID 21829381 DOI: 10.1371/Journal.Pgen.1002201 |
0.757 |
|
| 2011 |
Ziółkowska NE, Karotki L, Rehman M, Huiskonen JT, Walther TC. Eisosome-driven plasma membrane organization is mediated by BAR domains. Nature Structural & Molecular Biology. 18: 854-6. PMID 21685922 DOI: 10.1038/Nsmb.2080 |
0.407 |
|
| 2011 |
Bewersdorf J, Farese RV, Walther TC. A new way to look at fat Nature Methods. 8: 132-133. PMID 21278725 DOI: 10.1038/Nmeth0211-132 |
0.619 |
|
| 2010 |
Walther TC, Olsen JV, Mann M. Yeast expression proteomics by high-resolution mass spectrometry. Methods in Enzymology. 470: 259-80. PMID 20946814 DOI: 10.1016/S0076-6879(10)70011-2 |
0.478 |
|
| 2010 |
Walther TC, Mann M. Mass spectrometry-based proteomics in cell biology. The Journal of Cell Biology. 190: 491-500. PMID 20733050 DOI: 10.1083/Jcb.201004052 |
0.42 |
|
| 2010 |
Aguilar PS, Fröhlich F, Rehman M, Shales M, Ulitsky I, Olivera-Couto A, Braberg H, Shamir R, Walter P, Mann M, Ejsing CS, Krogan NJ, Walther TC. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nature Structural & Molecular Biology. 17: 901-8. PMID 20526336 DOI: 10.1038/Nsmb.1829 |
0.626 |
|
| 2010 |
Walther TC. Keeping sphingolipid levels nORMal. Proceedings of the National Academy of Sciences of the United States of America. 107: 5701-2. PMID 20304791 DOI: 10.1073/Pnas.1001503107 |
0.528 |
|
| 2010 |
Aguilar PS, Heiman MG, Walther TC, Engel A, Schwudke D, Gushwa N, Kurzchalia T, Walter P. Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating. Proceedings of the National Academy of Sciences of the United States of America. 107: 4170-5. PMID 20150508 DOI: 10.1073/Pnas.0914094107 |
0.747 |
|
| 2009 |
Krahmer N, Guo Y, Farese RV, Walther TC. SnapShot: Lipid Droplets Cell. 139. PMID 19945384 DOI: 10.1016/J.Cell.2009.11.023 |
0.827 |
|
| 2009 |
Farese RV, Walther TC. Lipid Droplets Finally Get a Little R-E-S-P-E-C-T Cell. 139: 855-860. PMID 19945371 DOI: 10.1016/J.Cell.2009.11.005 |
0.658 |
|
| 2009 |
Soufi B, Kelstrup CD, Stoehr G, Fröhlich F, Walther TC, Olsen JV. Global analysis of the yeast osmotic stress response by quantitative proteomics. Molecular Biosystems. 5: 1337-46. PMID 19823750 DOI: 10.1039/B902256B |
0.352 |
|
| 2009 |
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science (New York, N.Y.). 325: 834-40. PMID 19608861 DOI: 10.1126/Science.1175371 |
0.508 |
|
| 2009 |
Fröhlich F, Moreira K, Aguilar PS, Hubner NC, Mann M, Walter P, Walther TC. A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling. The Journal of Cell Biology. 185: 1227-42. PMID 19564405 DOI: 10.1083/Jcb.200811081 |
0.805 |
|
| 2009 |
Guo Y, Cordes KR, Farese RV, Walther TC. Lipid droplets at a glance Journal of Cell Science. 122: 749-752. PMID 19261844 DOI: 10.1242/Jcs.037630 |
0.687 |
|
| 2009 |
Wang H, Kakaradov B, Collins SR, Karotki L, Fiedler D, Shales M, Shokat KM, Walther TC, Krogan NJ, Koller D. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Molecular & Cellular Proteomics : McP. 8: 1361-81. PMID 19176519 DOI: 10.1074/Mcp.M800490-Mcp200 |
0.313 |
|
| 2009 |
Berchtold D, Walther TC. TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain. Molecular Biology of the Cell. 20: 1565-75. PMID 19144819 DOI: 10.1091/Mbc.E08-10-1001 |
0.412 |
|
| 2009 |
Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. The Journal of Biological Chemistry. 284: 5352-61. PMID 19049983 DOI: 10.1074/Jbc.M805768200 |
0.694 |
|
| 2009 |
Walther TC, Farese RV. The life of lipid droplets Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1791: 459-466. PMID 19041421 DOI: 10.1016/J.Bbalip.2008.10.009 |
0.681 |
|
| 2009 |
Moreira KE, Walther TC, Aguilar PS, Walter P. Pil1 controls eisosome biogenesis. Molecular Biology of the Cell. 20: 809-18. PMID 19037108 DOI: 10.1091/Mbc.E08-03-0313 |
0.804 |
|
| 2008 |
de Godoy LM, Olsen JV, Cox J, Nielsen ML, Hubner NC, Fröhlich F, Walther TC, Mann M. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature. 455: 1251-4. PMID 18820680 DOI: 10.1038/Nature07341 |
0.526 |
|
| 2008 |
Matic I, Macek B, Hilger M, Walther TC, Mann M. Phosphorylation of SUMO-1 occurs in vivo and is conserved through evolution. Journal of Proteome Research. 7: 4050-7. PMID 18707152 DOI: 10.1021/Pr800368M |
0.478 |
|
| 2008 |
Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 453: 657-61. PMID 18408709 DOI: 10.1038/Nature06928 |
0.771 |
|
| 2007 |
Walther TC, Aguilar PS, Fröhlich F, Chu F, Moreira K, Burlingame AL, Walter P. Pkh-kinases control eisosome assembly and organization. The Embo Journal. 26: 4946-55. PMID 18034155 DOI: 10.1038/Sj.Emboj.7601933 |
0.794 |
|
| 2006 |
Walther TC, Brickner JH, Aguilar PS, Bernales S, Pantoja C, Walter P. Eisosomes mark static sites of endocytosis. Nature. 439: 998-1003. PMID 16496001 DOI: 10.1038/Nature04472 |
0.824 |
|
| 2005 |
Hetzer MW, Walther TC, Mattaj IW. Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annual Review of Cell and Developmental Biology. 21: 347-80. PMID 16212499 DOI: 10.1146/Annurev.Cellbio.21.090704.151152 |
0.733 |
|
| 2003 |
Walther TC, Askjaer P, Gentzel M, Habermann A, Griffiths G, Wilm M, Mattaj IW, Hetzer M. RanGTP mediates nuclear pore complex assembly. Nature. 424: 689-94. PMID 12894213 DOI: 10.1038/Nature01898 |
0.715 |
|
| 2003 |
Walther TC, Alves A, Pickersgill H, Loïodice I, Hetzer M, Galy V, Hülsmann BB, Köcher T, Wilm M, Allen T, Mattaj IW, Doye V. The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell. 113: 195-206. PMID 12705868 DOI: 10.1016/S0092-8674(03)00235-6 |
0.701 |
|
| 2002 |
Kuersten S, Arts GJ, Walther TC, Englmeier L, Mattaj IW. Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains. Molecular and Cellular Biology. 22: 5708-20. PMID 12138183 DOI: 10.1128/Mcb.22.16.5708-5720.2002 |
0.525 |
|
| 2002 |
Walther TC, Pickersgill HS, Cordes VC, Goldberg MW, Allen TD, Mattaj IW, Fornerod M. The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import. The Journal of Cell Biology. 158: 63-77. PMID 12105182 DOI: 10.1083/Jcb.200202088 |
0.578 |
|
| 2001 |
Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW. Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nature Cell Biology. 3: 1086-91. PMID 11781570 DOI: 10.1038/Ncb1201-1086 |
0.721 |
|
| 2001 |
Walther TC, Fornerod M, Pickersgill H, Goldberg M, Allen TD, Mattaj IW. The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. The Embo Journal. 20: 5703-14. PMID 11598013 DOI: 10.1093/Emboj/20.20.5703 |
0.581 |
|
| 2000 |
Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW. GTP hydrolysis by Ran is required for nuclear envelope assembly. Molecular Cell. 5: 1013-24. PMID 10911995 DOI: 10.1016/S1097-2765(00)80266-X |
0.712 |
|
| Show low-probability matches. |