Year |
Citation |
Score |
2023 |
Irobalieva RN, Manolaridis I, Jackson SM, Ni D, Pardon E, Stahlberg H, Steyaert J, Locher KP. Structural basis of the allosteric inhibition of human ABCG2 by nanobodies. Journal of Molecular Biology. 168234. PMID 37597690 DOI: 10.1016/j.jmb.2023.168234 |
0.348 |
|
2021 |
Yu Q, Ni D, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP. Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nature Communications. 12: 4376. PMID 34282134 DOI: 10.1038/s41467-021-24651-2 |
0.345 |
|
2021 |
Kowal J, Ni D, Jackson SM, Manolaridis I, Stahlberg H, Locher KP. Structural basis of drug recognition by the multidrug transporter ABCG2. Journal of Molecular Biology. 166980. PMID 33838147 DOI: 10.1016/j.jmb.2021.166980 |
0.327 |
|
2020 |
Antoni F, Bause M, Scholler M, Bauer S, Stark SA, Jackson SM, Manolaridis I, Locher KP, König B, Buschauer A, Bernhardt G. Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). European Journal of Medicinal Chemistry. 191: 112133. PMID 32105979 DOI: 10.1016/J.Ejmech.2020.112133 |
0.317 |
|
2019 |
Hassan KA, Naidu V, Edgerton JR, Mettrick KA, Liu Q, Fahmy L, Li L, Jackson SM, Ahmad I, Sharples D, Henderson PJF, Paulsen IT. Short-chain diamines are the physiological substrates of PACE family efflux pumps. Proceedings of the National Academy of Sciences of the United States of America. PMID 31416917 DOI: 10.1073/Pnas.1901591116 |
0.655 |
|
2018 |
Manolaridis I, Jackson SM, Taylor NMI, Kowal J, Stahlberg H, Locher KP. Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature. PMID 30405239 DOI: 10.1038/s41586-018-0680-3 |
0.494 |
|
2018 |
Jackson SM, Manolaridis I, Kowal J, Zechner M, Taylor NMI, Bause M, Bauer S, Bartholomaeus R, Bernhardt G, Koenig B, Buschauer A, Stahlberg H, Altmann KH, Locher KP. Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature Structural & Molecular Biology. PMID 29610494 DOI: 10.1038/S41594-018-0049-1 |
0.455 |
|
2017 |
Calabrese AN, Jackson SM, Jones LN, Beckstein O, Heinkel F, Gsponer J, Sharples D, Sans M, Kokkinidou M, Pearson AR, Radford SE, Ashcroft AE, Henderson PJF. Topological dissection of the membrane transport protein Mhp1 derived from cysteine accessibility and mass spectrometry. Analytical Chemistry. PMID 28726379 DOI: 10.1021/Acs.Analchem.7B01310 |
0.58 |
|
2017 |
Taylor NMI, Manolaridis I, Jackson SM, Kowal J, Stahlberg H, Locher KP. Structure of the human multidrug transporter ABCG2. Nature. PMID 28554189 DOI: 10.1038/Nature22345 |
0.456 |
|
2015 |
Hassan KA, Elbourne LD, Li L, Gamage HK, Liu Q, Jackson SM, Sharples D, Kolstø AB, Henderson PJ, Paulsen IT. An ace up their sleeve: a transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens. Frontiers in Microbiology. 6: 333. PMID 25954261 DOI: 10.3389/Fmicb.2015.00333 |
0.573 |
|
2015 |
Polyakova A, Jackson S, Cameron A, Henderson PJF, Pearson AR. The ins-and-out of a membrane protein; structure-function through alternative crystallisation and harvesting approaches Acta Crystallographica Section a Foundations and Advances. 71: s49-s49. DOI: 10.1107/S2053273315099246 |
0.415 |
|
2014 |
Simmons KJ, Jackson SM, Brueckner F, Patching SG, Beckstein O, Ivanova E, Geng T, Weyand S, Drew D, Lanigan J, Sharples DJ, Sansom MS, Iwata S, Fishwick CW, Johnson AP, et al. Molecular mechanism of ligand recognition by membrane transport protein, Mhp1. The Embo Journal. 33: 1831-44. PMID 24952894 DOI: 10.15252/Embj.201387557 |
0.719 |
|
2013 |
Hassan KA, Jackson SM, Penesyan A, Patching SG, Tetu SG, Eijkelkamp BA, Brown MH, Henderson PJ, Paulsen IT. Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 20254-9. PMID 24277845 DOI: 10.1073/Pnas.1317052110 |
0.705 |
|
2010 |
Weyand S, Ma P, Saidijam M, Baldwin J, Beckstein O, Jackson S, Suzuki S, Patching SG, Shimamura T, Sansom MSP, Iwata S, Cameron AD, Baldwin SA, Henderson PJF. The Nucleobase‐Cation‐Symport‐1 family of membrane transport proteins Handbook of Metalloproteins. |
0.68 |
|
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