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Phillip Crews - Publications

Affiliations: 
Chemistry & Biochemistry University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
chemistry of tropical marine sponges and marine-derived fungi
Website:
http://www.chemistry.ucsc.edu/faculty/singleton.php?&singleton=true&cruz_id=pcrews

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Torres TC, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, ... ... Crews P, et al. Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging. Biorxiv : the Preprint Server For Biology. PMID 38077060 DOI: 10.1101/2023.11.27.568896  0.486
2022 Takahashi-Ruiz L, Morris JD, Crews P, Johnson TA, Risinger AL. In Vivo Evaluation of (-)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site. Molecules (Basel, Switzerland). 27. PMID 35807495 DOI: 10.3390/molecules27134244  0.51
2022 Morris JD, Takahashi-Ruiz L, Persi LN, Summers JC, McCauley EP, Chan PYW, Amberchan G, Lizama-Chamu I, Coppage DA, Crews P, Risinger AL, Johnson TA. Re-evaluation of the Fijianolide/Laulimalide Chemotype Suggests an Alternate Mechanism of Action for C-15/C-20 Analogs. Acs Omega. 7: 8824-8832. PMID 35309480 DOI: 10.1021/acsomega.1c07146  0.547
2020 McCauley EP, Piña IC, Thompson AD, Bashir K, Weinberg M, Kurz SL, Crews P. Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates. The Journal of Antibiotics. PMID 32507851 DOI: 10.1038/S41429-020-0330-5  0.373
2020 Shi Y, Bray W, Smith AJ, Zhou W, Calaoagan J, Lagisetti C, Sambucetti L, Crews P, Lokey RS, Webb TR. An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications. Plos One. 15: e0233672. PMID 32469945 DOI: 10.1371/Journal.Pone.0233672  0.362
2020 Johnson TA, Morris JD, Coppage DA, Cook CV, Persi LN, Ogarrio MA, Garcia TC, McIntosh NL, McCauley EP, Media J, Maheshwari M, Valeriote FA, Shaw J, Crews P. Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 Configuration. Acs Medicinal Chemistry Letters. 11: 108-113. PMID 32071675 DOI: 10.1021/Acsmedchemlett.9B00302  0.566
2020 McCauley EP, Smith GC, Crews P. Unraveling Structures Containing Highly Conjugated Pyrrolo[4,3,2-]quinoline Cores That Are Deficient in Diagnostic Proton NMR Signals. Journal of Natural Products. PMID 31904956 DOI: 10.1021/Acs.Jnatprod.9B01111  0.472
2019 Trianto A, Radjasa OK, Sabdono A, Muchlissin SI, Afriyanto R, Sulistiowati S, Radjasa SK, Crews P, Mccauley E. Exploration culturable bacterial symbionts of sponges from Ternate Islands, Indonesia Biodiversitas. 20: 776-782. DOI: 10.13057/Biodiv/D200323  0.404
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h  0.481
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/C7Np00064B  0.529
2018 Lorig-Roach N, Hamkins-Indik F, Johnson TA, Tenney K, Valeriote FA, Crews P. The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells. Tetrahedron. 74: 217-223. PMID 29576661 DOI: 10.1016/J.Tet.2017.11.029  0.61
2018 McCauley E, Radjasa OK, Trianto A, Crews MS, Smith A, Smith GC, Zerebinski P, Sabdono A, Crews P. The UNDIP-UCSC campaign to culture chemically prolific gram-negative bacteria from Indonesian Jaspis sponges Arkivoc. 2018: 123-131. DOI: 10.24820/Ark.5550190.P010.505  0.404
2017 McCauley EP, Lam H, Lorig-Roach N, Luu J, Lloyd C, Tenney K, Pietraszkiewicz H, Diaz C, Valeriote FA, Auerbuch V, Crews P. Investigation of the Physical and Bioactive Properties of Bromo- and Iodo-Containing Sponge-Derived Compounds Possessing an Oxyphenylethanamine Core. Journal of Natural Products. PMID 29144750 DOI: 10.1021/Acs.Jnatprod.7B00694  0.451
2017 Zhang H, Dong M, Chen J, Wang H, Tenney K, Crews P. Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas. Marine Drugs. 15. PMID 29117128 DOI: 10.3390/Md15110351  0.375
2017 Fraley AE, Garcia-Borràs M, Tripathi A, Khare D, Mercado-Marin EV, Tran H, Dan Q, Webb G, Watts K, Crews P, Sarpong R, Williams RM, Smith JL, Houk KN, Sherman DH. Function and structure of MalA/MalA', iterative halogenases for late-stage C-H functionalization of indole alkaloids. Journal of the American Chemical Society. PMID 28777910 DOI: 10.1021/Jacs.7B06773  0.795
2017 Lorig-Roach N, Still PC, Coppage D, Compton JE, Crews MS, Navarro G, Tenney K, Crews P. Evaluating Nitrogen-Containing Biosynthetic Products Produced by Saltwater Culturing of Several California Littoral Zone Gram-Negative Bacteria. Journal of Natural Products. PMID 28777571 DOI: 10.1021/Acs.Jnatprod.7B00302  0.796
2017 Lin S, McCauley EP, Lorig-Roach N, Tenney K, Naphen CN, Yang AM, Johnson TA, Hernadez T, Rattan R, Valeriote FA, Crews P. Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues. Marine Drugs. 15. PMID 28353633 DOI: 10.3390/Md15040098  0.64
2017 White KN, Tenney K, Crews P. The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects. Journal of Natural Products. PMID 28185457 DOI: 10.1021/Acs.Jnatprod.6B00970  0.396
2017 Zhang H, Dong M, Wang H, Crews P. Secondary Metabolites from the Marine Sponge Genus Phyllospongia. Marine Drugs. 15. PMID 28067826 DOI: 10.3390/Md15010012  0.354
2016 Zhang H, Crews P, Tenney K, Valeriote FA. Cytotoxic Phyllactone Analogs from the Marine Sponge Phyllospongia papyrecea. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 27748180 DOI: 10.2174/1573406412666161007150828  0.396
2016 Johnson TA, Milan-Lobo L, Che T, Ferwerda M, Lambo E, McIntosh NL, Li F, He L, Lorig-Roach N, Crews P, Whistler JL. Identification of the first marine-derived opioid receptor "balanced" agonist with a signaling profile that resembles the endorphins. Acs Chemical Neuroscience. PMID 27744679 DOI: 10.1021/Acschemneuro.6B00167  0.564
2016 Zhai MM, Li J, Jiang CX, Shi YP, Di DL, Crews P, Wu QX. The Bioactive Secondary Metabolites from Talaromyces species. Natural Products and Bioprospecting. PMID 26746215 DOI: 10.1007/S13659-015-0081-3  0.407
2015 Zhai MM, Niu HT, Li J, Xiao H, Shi YP, Di DL, Crews P, Wu QX. Talaromycolides A-C, Novel Phenyl-Substituted Phthalides Isolated from the Green Chinese Onion-Derived Fungus Talaromyces pinophilus AF-02. Journal of Agricultural and Food Chemistry. PMID 26466717 DOI: 10.1021/Acs.Jafc.5B04296  0.475
2015 Zhang H, Loveridge ST, Tenney K, Crews P. A new 3-alkylpyridine alkaloid from the marine sponge Haliclona sp. and its cytotoxic activity. Natural Product Research. 1-4. PMID 26165203 DOI: 10.1080/14786419.2015.1054826  0.479
2015 Ahlbach CL, Lexa KW, Bockus AT, Chen V, Crews P, Jacobson MP, Lokey RS. Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products. Future Medicinal Chemistry. 1-10. PMID 26067057 DOI: 10.4155/Fmc.15.78  0.314
2015 Theodore CM, Lorig-Roach N, Still PC, Johnson TA, Draškovi? M, Schwochert JA, Naphen CN, Crews MS, Barker SA, Valeriote FA, Lokey RS, Crews P. Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides. Journal of Natural Products. 78: 441-52. PMID 25699470 DOI: 10.1021/Np500840N  0.827
2015 Lorig-Roach N, Johnson T, Valeriote F, Crews P. A new brominated indole from Haplosclerida with selective cytotoxicity against the PANC-1 tumor cell line Planta Medica. 81. DOI: 10.1055/S-0035-1556364  0.304
2014 Wang XZ, Luo XH, Xiao J, Zhai MM, Yuan Y, Zhu Y, Crews P, Yuan CS, Wu QX. Pyrone derivatives from the endophytic fungus Alternaria tenuissima SP-07 of Chinese herbal medicine Salvia przewalskii Fitoterapia. 99: 184-190. PMID 25284429 DOI: 10.1016/J.Fitote.2014.09.017  0.46
2014 La Clair JJ, Loveridge ST, Tenney K, O'Neil-Johnson M, Chapman E, Crews P. In situ natural product discovery via an artificial marine sponge. Plos One. 9: e100474. PMID 25004127 DOI: 10.1371/Journal.Pone.0100474  0.373
2014 Still PC, Johnson TA, Theodore CM, Loveridge ST, Crews P. Scrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stage. Journal of Natural Products. 77: 690-702. PMID 24571234 DOI: 10.1021/Np500041X  0.808
2014 Mejia EJ, Loveridge ST, Stepan G, Tsai A, Jones GS, Barnes T, White KN, DraÅ¡ković M, Tenney K, Tsiang M, Geleziunas R, Cihlar T, Pagratis N, Tian Y, Yu H, ... Crews P, et al. Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells. Journal of Natural Products. 77: 618-24. PMID 24495105 DOI: 10.1021/Np400889X  0.365
2014 Rodríguez J, Nieto RM, Blanco M, Valeriote FA, Jiménez C, Crews P. Thelepamide: An unprecedented ketide-amino acid from thelepus crispus, a marine annelid worm Organic Letters. 16: 464-467. PMID 24359301 DOI: 10.1021/Ol403350E  0.369
2013 Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z  0.324
2013 Rohena CC, Peng J, Johnson TA, Crews P, Mooberry SL. Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases. Biochemical Pharmacology. 85: 1104-14. PMID 23399639 DOI: 10.1016/J.Bcp.2013.01.030  0.524
2013 Mejia EJ, Magranet LB, De Voogd NJ, Tendyke K, Qiu D, Shen YY, Zhou Z, Crews P. Structures and cytotoxic evaluation of new and known acyclic Ene-Ynes from an American Samoa Petrosia sp. Sponge Journal of Natural Products. 76: 425-432. PMID 23368996 DOI: 10.1021/Np3008446  0.418
2013 Rohena CC, Peng J, Johnson TA, Crews P, Mooberry SL. Abstract 4501: Diverse microtubule stabilizers cause differential expression of mitotic kinases leading to distinct centrosomal and mitotic defects. Cancer Research. 73: 4501-4501. DOI: 10.1158/1538-7445.Am2013-4501  0.51
2013 Jiang HL, Wang XZ, Xiao J, Luo XH, Yao XJ, Zhao YY, Chen YJ, Crews P, Wu QX. New abietane diterpenoids from the roots of Salvia przewalskii Tetrahedron. 69: 6687-6692. DOI: 10.1016/J.Tet.2013.05.115  0.377
2012 Valeriote FA, Tenney K, Media J, Pietraszkiewicz H, Edelstein M, Johnson TA, Amagata T, Crews P. Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program. Journal of Experimental Therapeutics & Oncology. 10: 119-34. PMID 23350352  0.588
2012 Jiang HL, Luo XH, Wang XZ, Yang JL, Yao XJ, Crews P, Valeriote FA, Wu QX. New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker Fitoterapia. 83: 1275-1280. PMID 22735600 DOI: 10.1016/J.Fitote.2012.06.005  0.414
2012 Johnson TA, Sohn J, Vaske YM, White KN, Cohen TL, Vervoort HC, Tenney K, Valeriote FA, Bjeldanes LF, Crews P. Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. Bioorganic & Medicinal Chemistry. 20: 4348-55. PMID 22705020 DOI: 10.1016/J.Bmc.2012.05.043  0.614
2012 Luo XH, Wang XZ, Jiang HL, Yang JL, Crews P, Valeriote FA, Wu QX. The biosynthetic products of Chinese insect medicine, Aspongopus chinensis Fitoterapia. 83: 754-758. PMID 22430116 DOI: 10.1016/J.Fitote.2012.03.002  0.474
2012 Wu QX, Jin XJ, Draskovic M, Crews MS, Tenney K, Valeriote FA, Yao XJ, Crews P. Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola. Phytochemistry Letters. 5: 114-117. PMID 22368725 DOI: 10.1016/J.Phytol.2011.11.005  0.39
2011 Johnson TA, Sohn J, Inman WD, Estee SA, Loveridge ST, Vervoort HC, Tenney K, Liu J, Ang KK, Ratnam J, Bray WM, Gassner NC, Shen YY, Lokey RS, McKerrow JH, ... ... Crews P, et al. Natural product libraries to accelerate the high-throughput discovery of therapeutic leads. Journal of Natural Products. 74: 2545-55. PMID 22129061 DOI: 10.1021/Np200673B  0.65
2011 Radjasa OK, Vaske YM, Navarro G, Vervoort HC, Tenney K, Linington RG, Crews P. Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants. Bioorganic & Medicinal Chemistry. 19: 6658-74. PMID 21835627 DOI: 10.1016/J.Bmc.2011.07.017  0.434
2011 Watts KR, Loveridge ST, Tenney K, Media J, Valeriote FA, Crews P. Utilizing DART mass spectrometry to pinpoint halogenated metabolites from a marine invertebrate-derived fungus. The Journal of Organic Chemistry. 76: 6201-8. PMID 21682275 DOI: 10.1021/Jo2009593  0.807
2011 Watts KR, Morinaka BI, Amagata T, Robinson SJ, Tenney K, Bray WM, Gassner NC, Lokey RS, Media J, Valeriote FA, Crews P. Biostructural features of additional jasplakinolide (jaspamide) analogues. Journal of Natural Products. 74: 341-51. PMID 21241058 DOI: 10.1021/Np100721G  0.797
2011 Vervoort HC, Drašković M, Crews P. Histone deacetylase inhibitors as a tool to up-regulate new fungal biosynthetic products: Isolation of EGM-556, a cyclodepsipeptide, from Microascus sp. Organic Letters. 13: 410-413. PMID 21174394 DOI: 10.1021/Ol1027199  0.383
2011 Calcul L, Tenney K, Ratnam J, McKerrow JH, Crews P. Corrigendum to: Structural Variations to the 9-N-Methyladeninium Diterpenoid Hybrid Commonly Isolated from Agelas Sponges Australian Journal of Chemistry. 64: 846-846. DOI: 10.1071/Ch10036_Co  0.48
2010 Hochmuth T, Niederkrüger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J. Linking chemical and microbial diversity in marine sponges: Possible role for poribacteria as producers of methyl-branched fatty acids Chembiochem. 11: 2572-2578. PMID 21077090 DOI: 10.1002/Cbic.201000510  0.329
2010 Watts KR, Tenney K, Crews P. The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules. Current Opinion in Biotechnology. 21: 808-18. PMID 20956079 DOI: 10.1016/J.Copbio.2010.09.015  0.791
2010 Wu QX, Crews MS, Draskovic M, Sohn J, Johnson TA, Tenney K, Valeriote FA, Yao XJ, Bjeldanes LF, Crews P. Azonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola. Organic Letters. 12: 4458-61. PMID 20866076 DOI: 10.1021/Ol101396N  0.578
2010 Morgan JB, Mahdi F, Liu Y, Coothankandaswamy V, Jekabsons MB, Johnson TA, Sashidhara KV, Crews P, Nagle DG, Zhou YD. The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor. Bioorganic & Medicinal Chemistry. 18: 5988-94. PMID 20637638 DOI: 10.1016/J.Bmc.2010.06.072  0.607
2010 Watts KR, Ratnam J, Ang KH, Tenney K, Compton JE, McKerrow J, Crews P. Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi. Bioorganic & Medicinal Chemistry. 18: 2566-74. PMID 20303767 DOI: 10.1016/J.Bmc.2010.02.034  0.797
2010 Robinson SJ, Morinaka BI, Amagata T, Tenney K, Bray WM, Gassner NC, Scott Lokey R, Crews P. New structures and bioactivity properties of jasplakinolide (jaspamide) analogues from marine sponges Journal of Medicinal Chemistry. 53: 1651-1661. PMID 20121114 DOI: 10.1021/Jm9013554  0.53
2010 Calcul L, Inman WD, Morris AA, Tenney K, Ratnam J, McKerrow JH, Valeriote FA, Crews P. Additional insights on the bastadins: Isolation of analogues from the sponge ianthella cf. reticulata and exploration of the oxime configurations Journal of Natural Products. 73: 365-372. PMID 20102170 DOI: 10.1021/Np9005986  0.408
2010 Shaw J, Valeriote FA, Media J, Johnson TA, Amagata T, Tenney K, Crews P. Development and validation of a rapid method for the detection of latrunculol A in plasma. Analytical and Bioanalytical Chemistry. 396: 1741-4. PMID 20043220 DOI: 10.1007/S00216-009-3385-5  0.461
2010 Johnson TA, Morgan MV, Aratow NA, Estee SA, Sashidhara KV, Loveridge ST, Segraves NL, Crews P. Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products. Journal of Natural Products. 73: 359-64. PMID 20030364 DOI: 10.1021/Np900565A  0.557
2010 Inman WD, Bray WM, Gassner NC, Scott Lokey R, Tenney K, Shen YY, Tendyke K, Suh T, Crews P. A β-carboline alkaloid from the Papua New Guinea Marine sponge Hyrtios reticulatus Journal of Natural Products. 73: 255-257. PMID 20000782 DOI: 10.1021/Np9005426  0.434
2010 Calcul L, Tenney K, Ratnam J, McKerrow JH, Crews P. Structural variations to the 9-N-methyladeninium diterpenoid hybrid commonly isolated from agelas sponges Australian Journal of Chemistry. 63: 915-921. DOI: 10.1071/Ch10036  0.48
2009 Robinson SJ, Hoobler EK, Riener M, Loveridge ST, Tenney K, Valeriote FA, Holman TR, Crews P. Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes. Journal of Natural Products. 72: 1857-63. PMID 19848434 DOI: 10.1021/Np900465E  0.463
2009 Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J. Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting. Nature Chemical Biology. 5: 494-501. PMID 19448639 DOI: 10.1038/Nchembio.176  0.784
2009 Johnson TA, Amagata T, Sashidhara KV, Oliver AG, Tenney K, Matainaho T, Ang KK, McKerrow JH, Crews P. The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis. Organic Letters. 11: 1975-8. PMID 19385671 DOI: 10.1021/Ol900446D  0.582
2009 Calcul L, Chow R, Oliver AG, Tenney K, White KN, Wood AW, Fiorilla C, Crews P. NMR strategy for unraveling structures of bioactive sponge-derived oxy-polyhalogenated diphenyl ethers. Journal of Natural Products. 72: 443-9. PMID 19323567 DOI: 10.1021/Np800737Z  0.476
2009 Sashidhara KV, White KN, Crews P. A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products Journal of Natural Products. 72: 588-603. PMID 19209899 DOI: 10.1021/Np800817Y  0.361
2009 Rubio BK, Tenney K, Ang KH, Abdulla M, Arkin M, McKerrow JH, Crews P. The marine sponge Diacarnus bismarckensis as a source of peroxiterpene inhibitors of Trypanosoma brucei, the causative agent of sleeping sickness Journal of Natural Products. 72: 218-222. PMID 19159277 DOI: 10.1021/Np800711A  0.806
2008 Amagata T, Johnson TA, Cichewicz RH, Tenney K, Mooberry SL, Media J, Edelstein M, Valeriote FA, Crews P. Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges. Journal of Medicinal Chemistry. 51: 7234-42. PMID 18942825 DOI: 10.1021/Jm8008585  0.729
2008 White KN, Amagata T, Oliver AG, Tenney K, Wenzel PJ, Crews P. Structure revision of spiroleucettadine, a sponge alkaloid with a bicyclic core meager in H-atoms. The Journal of Organic Chemistry. 73: 8719-22. PMID 18925788 DOI: 10.1021/Jo800960W  0.353
2008 Johnson TA, Amagata T, Oliver AG, Tenney K, Valeriote FA, Crews P. The unexpected isolation of CTP-431, a novel thiopyrone from the sponge Cacospongia mycofijiensis. The Journal of Organic Chemistry. 73: 7255-9. PMID 18715038 DOI: 10.1021/Jo801096M  0.593
2008 Rubio BK, Robinson SJ, Avalos CE, Valeriote FA, De Voogd NJ, Crews P. Revisiting the sponge sources, stereostructure, and biological activity of cyclocinamide A Journal of Natural Products. 71: 1475-1478. PMID 18590311 DOI: 10.1021/Np800230D  0.809
2008 Johnson TA, Morgan M, Aratow N, Tenney K, Loveridge ST, Valeriote FA, Crews P. Using Accelerated Solvent Extraction (ASE) followed by parallel chromatography to rapidly pinpoint new chemistry and scale-up the isolation of bioactive marine natural products for in vivo evaluation Planta Medica. 74. DOI: 10.1055/S-0028-1084543  0.375
2008 Robinson S, Riener M, Tenney K, Loveridge S, Mooberry S, Valeriote F, Crews P. Isolation of Puupehenone analogs and further development of the structure activity relationship within this compound class Planta Medica. 74. DOI: 10.1055/S-0028-1084502  0.46
2007 Boot CM, Amagata T, Tenney K, Compton JE, Pietraszkiewicz H, Valeriote FA, Crews P. Four Classes of Structurally Unusual Peptides from Two Marine-Derived Fungi: Structures and Bioactivities. Tetrahedron. 63: 9903-9914. PMID 18820723 DOI: 10.1016/J.Tet.2007.06.034  0.753
2007 Boot CM, Gassner NC, Compton JE, Tenney K, Tamble CM, Lokey RS, Holman TR, Crews P. Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen Journal of Natural Products. 70: 1672-1675. PMID 17929896 DOI: 10.1021/Np070307C  0.764
2007 Deschamps JD, Gautschi JT, Whitman S, Johnson TA, Gassner NC, Crews P, Holman TR. Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. Bioorganic & Medicinal Chemistry. 15: 6900-8. PMID 17826100 DOI: 10.1016/J.Bmc.2007.08.015  0.59
2007 Johnson TA, Tenney K, Cichewicz RH, Morinaka BI, White KN, Amagata T, Subramanian B, Media J, Mooberry SL, Valeriote FA, Crews P. Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties. Journal of Medicinal Chemistry. 50: 3795-803. PMID 17622130 DOI: 10.1021/Jm070410Z  0.751
2007 Robinson SJ, Tenney K, Yee DF, Martinez L, Media JE, Valeriote FA, Van Soest RWM, Crews P. Probing the bioactive constituents from chemotypes of the sponge Psammocinia aff. bulbosa Journal of Natural Products. 70: 1002-1009. PMID 17559267 DOI: 10.1021/Np070171I  0.449
2007 Li HJ, Amagata T, Tenney K, Crews P. Additional scalarane sesterterpenes from the sponge Phyllospongia papyracea Journal of Natural Products. 70: 802-807. PMID 17455979 DOI: 10.1021/Np070020F  0.436
2007 Rubio BK, Van Soest RWM, Crews P. Extending the record of meroditerpenes from Cacospongia marine sponges Journal of Natural Products. 70: 628-631. PMID 17346077 DOI: 10.1021/Np060633C  0.79
2007 Piña IC, White KN, Cabrera G, Rivero E, Crews P. Bromopyrrole carboxamide biosynthetic products from the Caribbean sponge Agelas dispar Journal of Natural Products. 70: 613-617. PMID 17335245 DOI: 10.1021/Np0606042  0.481
2007 Gassner NC, Tamble CM, Bock JE, Cotton N, White KN, Tenney K, St. Onge RP, Proctor MJ, Giaever G, Nislow C, Davis RW, Crews P, Holman TR, Lokey RS. Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay Journal of Natural Products. 70: 383-390. PMID 17291044 DOI: 10.1021/Np060555T  0.382
2007 Ralifo P, Sanchez L, Gassner NC, Tenney K, Lokey RS, Holman TR, Valeriote FA, Crews P. Pyrroloacridine alkaloids from Plakortis quasiamphiaster: Structures and bioactivity Journal of Natural Products. 70: 95-99. PMID 17253856 DOI: 10.1021/Np060585W  0.817
2007 Wegerski CJ, Hammond J, Tenney K, Matainaho T, Crews P. A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei Journal of Natural Products. 70: 89-94. PMID 17253855 DOI: 10.1021/Np060464W  0.36
2007 Ralifo P, Tenney K, Valeriote FA, Crews P. A distinctive structural twist in the aminoimidazole alkaloids from a calcareous marine sponge: Isolation and characterization of leucosolenamines A and B Journal of Natural Products. 70: 33-38. PMID 17253846 DOI: 10.1021/Np060462B  0.821
2007 Gautschi JT, Tenney K, Compton J, Crews P. Chemical Investigations of a Deep Water Marine-Derived Fungus: Simple Amino Acid Derivatives from an Arthrinium sp Natural Product Communications. 2. DOI: 10.1177/1934578X0700200506  0.312
2007 Boot CM, Amagata T, Tenney K, Compton JE, Pietraszkiewicz H, Valeriote FA, Crews P. Four classes of structurally unusual peptides from two marine-derived fungi: structures and bioactivities Tetrahedron. 63: 9903-9914. DOI: 10.1016/j.tet.2007.06.034  0.7
2006 Amagata T, Morinaka BI, Amagata A, Tenney K, Valeriote FA, Lobkovsky E, Clardy J, Crews P. A chemical study of cyclic depsipeptides produced by a sponge-derived fungus Journal of Natural Products. 69: 1560-1565. PMID 17125221 DOI: 10.1021/Np060178K  0.44
2006 Sonnenschein RN, Johnson TA, Tenney K, Valeriote FA, Crews P. A reassignment of (-)-mycothiazole and the isolation of a related diol. Journal of Natural Products. 69: 145-7. PMID 16441088 DOI: 10.1021/Np0503597  0.65
2006 Boot CM, Tenney K, Valeriote FA, Crews P. Highly N-methylated linear peptides produced by an atypical sponge-derived Acremonium sp. Journal of Natural Products. 69: 83-92. PMID 16441074 DOI: 10.1021/Np0503653  0.743
2006 Wegerski CJ, Sonnenschein RN, Cabriales F, Valeriote FA, Matainaho T, Crews P. Stereochemical challenges in characterizing nitrogenous spiro-axane sesquiterpenes from the Indo-Pacific sponges Amorphinopsis and Axinyssa Tetrahedron. 62: 10393-10399. DOI: 10.1016/J.Tet.2006.08.070  0.441
2005 Christian OE, Compton J, Christian KR, Mooberry SL, Valeriote FA, Crews P. Using jasplakinolide to turn on pathways that enable the isolation of new chaetoglobosins from Phomospis asparagi Journal of Natural Products. 68: 1592-1597. PMID 16309305 DOI: 10.1021/Np050293F  0.473
2005 Segraves NL, Crews P. Investigation of brominated tryptophan alkaloids from two thorectidae sponges: Thorectandra and Smenospongia Journal of Natural Products. 68: 1484-1488. PMID 16252912 DOI: 10.1021/Np0501334  0.44
2005 Cichewicz RH, Clifford LJ, Lassen PR, Cao X, Freedman TB, Nafie LA, Deschamps JD, Kenyon VA, Flanary JR, Holman TR, Crews P. Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis. Bioorganic & Medicinal Chemistry. 13: 5600-12. PMID 16039133 DOI: 10.1016/J.Bmc.2005.06.020  0.669
2005 Segraves NL, Crews P. A Madagascar sponge Batzella sp. as a source of alkylated iminosugars Journal of Natural Products. 68: 118-121. PMID 15679333 DOI: 10.1021/Np049763G  0.458
2004 Ralifo P, Crews P. A new structural theme in the imidazole-containing alkaloids from a calcareous Leucetta sponge Journal of Organic Chemistry. 69: 9025-9029. PMID 15609934 DOI: 10.1021/Jo048789+  0.814
2004 Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: Archetypes for a unique class of selective and recyclable inhibitors Journal of the American Chemical Society. 126: 14910-14920. PMID 15535718 DOI: 10.1021/Ja046082Z  0.658
2004 Wegerski CJ, France D, Cornell-Kennon S, Crews P. Using a kinase screen to investigate the constituents of the sponge Stelletta clavosa obtained from diverse habitats Bioorganic and Medicinal Chemistry. 12: 5631-5637. PMID 15465341 DOI: 10.1016/J.Bmc.2004.07.061  0.397
2004 Gautschi JT, Whitman S, Holman TR, Crews P. An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge Journal of Natural Products. 67: 1256-1261. PMID 15332838 DOI: 10.1021/Np0340495  0.434
2004 Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. Journal of Medicinal Chemistry. 47: 4060-5. PMID 15267244 DOI: 10.1021/Jm049872S  0.727
2004 Vilozny B, Amagata T, Mooberry SL, Crews P. A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica Journal of Natural Products. 67: 1055-1057. PMID 15217296 DOI: 10.1021/Np0340753  0.428
2004 Cichewicz RH, Valeriote FA, Crews P. Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family Organic Letters. 6: 1951-1954. PMID 15176791 DOI: 10.1021/Ol049503Q  0.589
2004 Segraves NL, Robinson SJ, Garcia D, Said SA, Fu X, Schmitz FJ, Pietraszkiewicz H, Valeriote FA, Crews P. Comparison of fascaplysin and related alkaloids: A study of structures, cytotoxicities, and sources Journal of Natural Products. 67: 783-792. PMID 15165138 DOI: 10.1021/Np049935+  0.488
2004 Gautschi JT, Amagata T, Amagata A, Valeriote FA, Mooberry SL, Crews P. Expanding the Strategies in Natural Product Studies of Marine-Derived Fungi: A Chemical Investigation of Penicillium Obtained from Deep Water Sediment Journal of Natural Products. 67: 362-367. PMID 15043411 DOI: 10.1021/Np030388M  0.417
2004 Sonnenschein RN, Farias JJ, Tenney K, Mooberry SL, Lobkovsky E, Clardy J, Crews P. A further study of the cytotoxic constituents of a milnamide-producing sponge Organic Letters. 6: 779-782. PMID 14986973 DOI: 10.1021/Ol036446C  0.498
2004 Lepourcelet M, Chen YNP, France DS, Wang H, Crews P, Petersen F, Bruseo C, Wood AW, Shivdasani RA. Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex Cancer Cell. 5: 91-102. PMID 14749129 DOI: 10.1016/S1535-6108(03)00334-9  0.329
2004 Gautschi JT, Amagata T, Amagata A, Valeriote FA, Mooberry SL, Crews P. Erratum: Expanding the strategies in natural product studies of marine-derived fungi: A chemical investigation of Penicillium obtained from deep water sediment (Journal of Natural Products (2004) 67 (362-367)) Journal of Natural Products. 67. DOI: 10.1021/Np040155A  0.323
2003 Amagata T, Amagata A, Tenney K, Valeriote FA, Lobkovsky E, Clardy J, Crews P. Unusual C25 Steroids Produced by a Sponge-Derived Penicillium citrinum Organic Letters. 5: 4393-4396. PMID 14602008 DOI: 10.1021/Ol0356800  0.458
2003 Amagata T, Rath C, Rigot JF, Tarlov N, Tenney K, Valeriote FA, Crews P. Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria Journal of Medicinal Chemistry. 46: 4342-4350. PMID 13678412 DOI: 10.1021/Jm030090T  0.482
2003 Edrada RA, Stessman CC, Crews P. Uniquely modified imidazole alkaloids from a calcareous Leucetta sponge. Journal of Natural Products. 66: 939-42. PMID 12880310 DOI: 10.1021/Np020503D  0.508
2003 Piña IC, Gautschi JT, Wang GY, Sanders ML, Schmitz FJ, France D, Cornell-Kennon S, Sambucetti LC, Remiszewski SW, Perez LB, Bair KW, Crews P. Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase. The Journal of Organic Chemistry. 68: 3866-73. PMID 12737565 DOI: 10.1021/Jo034248T  0.421
2003 Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases Journal of Natural Products. 66: 230-235. PMID 12608855 DOI: 10.1021/Np020462L  0.62
2003 Crews P, Clark DP, Tenney K. Variation in the alkaloids among indo-pacific Leucetta sponges. Journal of Natural Products. 66: 177-82. PMID 12608847 DOI: 10.1021/Np020371O  0.627
2003 Piña IC, Sanders ML, Crews P. Puupehenone congeners from an indo-pacific hyrtios sponge. Journal of Natural Products. 66: 2-6. PMID 12542334 DOI: 10.1021/Np020279S  0.407
2003 Crews P, Gerwick WH, Schmitz FJ, France D, Bair KW, Wright AE, Hallock Y. Molecular approaches to discover marine natural product anticancer leads - An update from a Drug Discovery Group Collaboration Pharmaceutical Biology. 41: 39-52. DOI: 10.1080/1388020039051743  0.348
2003 Segraves NL, Lopez S, Johnson TA, Said SA, Fu X, Schmitz FJ, Pietraszkiewicz H, Valeriote FA, Crews P. Structures and cytotoxicities of fascaplysin and related alkaloids from two marine phyla - Fascaplysinopsis sponges and Didemnum tunicates Tetrahedron Letters. 44: 3471-3475. DOI: 10.1016/S0040-4039(03)00671-3  0.681
2002 Thale Z, Johnson T, Tenney K, Wenzel PJ, Lobkovsky E, Clardy J, Media J, Pietraszkiewicz H, Valeriote FA, Crews P. Structures and cytotoxic properties of sponge-derived bisannulated acridines. The Journal of Organic Chemistry. 67: 9384-91. PMID 12492342 DOI: 10.1021/Jo026459O  0.81
2001 Kinder FR, Versace RW, Bair KW, Bontempo JM, Cesarz D, Chen S, Crews P, Czuchta AM, Jagoe CT, Mou Y, Nemzek R, Phillips PE, Tran LD, Wang RM, Weltchek S, et al. Synthesis and antitumor activity of ester-modified analogues of bengamide B. Journal of Medicinal Chemistry. 44: 3692-9. PMID 11606134 DOI: 10.1021/Jm010188C  0.389
2001 Carroll J, Jonsson EN, Ebel R, Hartman MS, Holman TR, Crews P. Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors Journal of Organic Chemistry. 66: 6847-6851. PMID 11597201 DOI: 10.1021/Jo015784T  0.386
2001 Thale Z, Kinder FR, Bair KW, Bontempo J, Czuchta AM, Versace RW, Phillips PE, Sanders ML, Wattanasin S, Crews P. Bengamides revisited: new structures and antitumor studies. The Journal of Organic Chemistry. 66: 1733-41. PMID 11262120 DOI: 10.1021/Jo001380+  0.789
2000 Wood WF, Hanke FJ, Kubo I, Carroll JA, Crews P. Buzonamine, a new alkaloid from the defensive secretion of the millipede, Buzonium crassipes. Biochemical Systematics and Ecology. 28: 305-312. PMID 10725589 DOI: 10.1016/S0305-1978(99)00068-X  0.304
2000 Varoglu M, Crews P. Biosynthetically diverse compounds from a saltwater culture of sponge-derived Aspergillus niger. Journal of Natural Products. 63: 41-3. PMID 10650076 DOI: 10.1021/Np9902892  0.445
2000 Crews P, Harrison B. New triterpene-ketides (Merotriterpenes), haliclotriol A and B, from an Indo-Pacific Haliclona sponge Tetrahedron. 56: 9039-9046. DOI: 10.1016/S0040-4020(00)00758-4  0.422
1998 Rahbaek L, Sperry S, Piper JE, Crews P. Deoxynortrichoharzin, a new polyketide from the saltwater culture of a sponge-derived Paecilomyces fungus. Journal of Natural Products. 61: 1571-3. PMID 9868170 DOI: 10.1021/Np980230F  0.343
1998 Harrison B, Crews P. Cyclic polyketide peroxides and acyclic diol analogues from the sponge Plakortis lita. Journal of Natural Products. 61: 1033-7. PMID 9722494 DOI: 10.1021/Np980093M  0.411
1998 Sperry S, Crews P. Dihydrotubastrines: phenethylguanidine analogues from the Indo-Pacific marine sponge Petrosia cf. contignata. Journal of Natural Products. 61: 859-61. PMID 9644088 DOI: 10.1021/Np980061Z  0.47
1998 Sperry S, Valeriote FA, Corbett TH, Crews P. Isolation and cytotoxic evaluation of marine sponge-derived norterpene peroxides. Journal of Natural Products. 61: 241-7. PMID 9514009 DOI: 10.1021/Np970467W  0.49
1998 Clark DP, Carroll J, Naylor S, Crews P. An antifungal cyclodepsipeptide, cyclolithistide A, from the sponge Theonella swinhoei Journal of Organic Chemistry. 63: 8757-8764. DOI: 10.1021/Jo980758P  0.612
1998 Wang GYS, Abrell LM, Avelar A, Borgeson BM, Crews P. New hirsutane based sesquiterpenes from salt water cultures of a marine sponge-derived fungus and the terrestrial fungus Coriolus consors Tetrahedron. 54: 7335-7342. DOI: 10.1016/S0040-4020(98)00398-6  0.368
1997 Varoglu M, Corbett TH, Valeriote FA, Crews P. Asperazine, a Selective Cytotoxic Alkaloid from a Sponge-Derived Culture of Aspergillus niger. The Journal of Organic Chemistry. 62: 7078-7079. PMID 11671801 DOI: 10.1021/Jo970568Z  0.319
1997 Harrison B, Crews P. The Structure and Probable Biogenesis of Helianane, a Heterocyclic Sesquiterpene, from the Indo-Pacific Sponge Haliclona?fascigera. The Journal of Organic Chemistry. 62: 2646-2648. PMID 11671613 DOI: 10.1021/Jo962175Q  0.337
1997 Jaspars M, Jackson E, Lobkovsky E, Clardy J, Diaz MC, Crews P. Using scalarane sesterterpenes to examine a sponge taxonomic anomaly. Journal of Natural Products. 60: 556-61. PMID 9214728 DOI: 10.1021/np960147x  0.531
1997 Sperry S, Crews P. Haliclostanone sulfate and halistanol sulfate from an Indo-Pacific Haliclona sponge. Journal of Natural Products. 60: 29-32. PMID 9014348 DOI: 10.1021/np960592s  0.393
1997 Murray LM, Johnson A, Diaz MC, Crews P. Geographic Variation in the Tropical Marine Sponge Jaspis cf. Johnstoni: An Unexpected Source of New Terpene-Benzenoids Journal of Organic Chemistry. 62: 5638-5641. DOI: 10.1021/Jo970036I  0.31
1997 Clark WD, Corbett T, Valeriote F, Crews P. Cyclocinamide A. An unusual cytotoxic halogenated hexapeptide from the marine sponge Psammocinia Journal of the American Chemical Society. 119: 9285-9286. DOI: 10.1021/Ja971638M  0.421
1997 Wang GYS, Borgeson BM, Crews P. Pitholides A-D, polyketides from a marine tunicate-derived culture of pithomyces sp Tetrahedron Letters. 38: 8449-8452. DOI: 10.1016/S0040-4039(97)10277-5  0.37
1996 Harrison B, Talapatra S, Lobkovsky E, Clardy J, Crews P. The structure and biogenetic origin of (-) halicyclamine B from a Xestospongia sponge Tetrahedron Letters. 37: 9151-9154. DOI: 10.1016/S0040-4039(96)02165-X  0.402
1996 Abrell LM, Borgeson B, Crews P. Chloro polyketides from the cultured fungus (Aspergillus) separated from a marine sponge Tetrahedron Letters. 37: 2331-2334. DOI: 10.1016/0040-4039(96)00277-8  0.418
1995 Adamczeski M, Reed AR, Crews P. New and known diketopiperazines from the Caribbean sponge, Calyx cf. podatypa. Journal of Natural Products. 58: 201-8. PMID 7769388 DOI: 10.1021/Np50116A007  0.424
1995 Horton PA, Crews P. The arenarans, sesquiterpene ethers from the marine sponge Dysidea arenaria. Journal of Natural Products. 58: 44-50. PMID 7760077 DOI: 10.1021/Np50115A005  0.445
1995 Varoglu M, Peters BM, Crews P. The structures and cytotoxic properties of polyketide peroxides from a Plakortis sponge. Journal of Natural Products. 58: 27-36. PMID 7760075 DOI: 10.1021/Np50115A003  0.446
1995 Jaspars M, Horton PA, Madrid LH, Crews P. The cyclorenierins, sesquiterpenoid quinols from the sponge Haliclona sp. collected in Vanuatu. Journal of Natural Products. 58: 609-12. PMID 7623039 DOI: 10.1021/Np50118A023  0.599
1995 Fu X, Schmitz FJ, Govindan M, Abbas SA, Hanson KM, Horton PA, Crews P, Laney M, Schatzman RC, Schatzman C. Enzyme inhibitors: new and known polybrominated phenols and diphenyl ethers from four Indo-Pacific Dysidea sponges. Journal of Natural Products. 58: 1384-91. PMID 7494145 DOI: 10.1021/Np50123A008  0.335
1995 Cheng X, Varoglu M, Abrell L, Crews P, Lobkovsky E, Clardy J. Chloriolins A-C, Chlorinated Sesquiterpenes Produced by Fungal Cultures Separated from a Jaspis Marine Sponge. [Erratum to document cited in CA121:250796] Journal of Organic Chemistry. 60: 1478-1478. DOI: 10.1021/Jo00110A067  0.637
1995 Clark WD, Crews P. A novel chlorinated ketide amino acid, herbamide A, from the marine sponge Dysidea herbacea Tetrahedron Letters. 36: 1185-1188. DOI: 10.1016/0040-4039(95)00029-C  0.349
1994 Slate DL, Lee RH, Rodriguez J, Crews P. The marine natural product, halistanol trisulfate, inhibits pp60v-src protein tyrosine kinase activity. Biochemical and Biophysical Research Communications. 203: 260-4. PMID 8074664 DOI: 10.1006/Bbrc.1994.2176  0.318
1994 Jaspers M, Pasupathy V, Crews P. A tetracyclic diamine alkaloid, halicyclamine A, from the marine sponge Haliclona sp Journal of Organic Chemistry. 59: 3253-3255. DOI: 10.1021/Jo00091A005  0.395
1994 Crews P, Farias JJ, Emrich R, Keifer PA. Milnamide A, an unusual cytotoxic tripeptide from the marine sponge Auletta cf. constricta Journal of Organic Chemistry. 59: 2932-2934. DOI: 10.1021/Jo00090A008  0.364
1994 Alvi KA, Jaspars M, Crews P, Strulovici B, Oto E. Penazetidine A, an alkaloid inhibitor of protein kinase C Bioorganic and Medicinal Chemistry Letters. 4: 2447-2450. DOI: 10.1016/S0960-894X(01)80407-8  0.578
1994 Jaspars M, Crews P. A triterpene tetrasaccharide, formoside, from the Caribbean Choristida sponge Erylus formosus Tetrahedron Letters. 35: 7501-7504. DOI: 10.1016/S0040-4039(00)78328-6  0.549
1994 Rodríguez J, Crews P. Revised structure of xestocyclamine A and description of a new analogue Tetrahedron Letters. 35: 4719-4722. DOI: 10.1016/S0040-4039(00)76950-4  0.38
1994 Jiménez C, Crews P. Mauritamide A and accompanying oroidin alkaloids from the sponge agelas mauritiana Tetrahedron Letters. 35: 1375-1378. DOI: 10.1016/S0040-4039(00)76222-8  0.471
1994 Jaspars M, Rali T, Laney M, Schatzman RC, Diaz MC, Schmitz FJ, Pordesimo EO, Crews P. The search for inosine 5′-Phosphate dehydrogenase (IMPDH) inhibitors from marine sponges. Evaluation of the bastadin alkaloids Tetrahedron. 50: 7367-7374. DOI: 10.1016/S0040-4020(01)90467-3  0.639
1994 Rodríguez J, Nieto RM, Hunter LM, Diaz MC, Crews P, Lobkovsky E, Clardy J. Variation among known kalihinol and new kalihinene diterpenes from the sponge Acanthella cavernosa Tetrahedron. 50: 11079-11090. DOI: 10.1016/S0040-4020(01)89411-4  0.457
1994 Crews P, Cheng XC, Adamczeski M, Rodríguez J, Jaspars M, Schmitz FJ, Traeger SC, Pordesimo EO. 1,2,3,4-tetrahydro-8-hydroxymanzamines, alkaloids from two different haplosclerid sponges Tetrahedron. 50: 13567-13574. DOI: 10.1016/S0040-4020(01)85671-4  0.564
1994 Avery MA, Gao F, Chong WKM, Hendrickson TF, Inman WD, Crews P. Synthesis, conformational analysis, and antimalarial activity of tricyclic analogs of artemisinin Tetrahedron. 50: 957-972. DOI: 10.1016/S0040-4020(01)80810-3  0.326
1994 Abrell LM, Cheng XC, Crews P. New nectriapyrones by salt water culture of a fungus separated from an Indo-Pacific sponge Tetrahedron Letters. 35: 9159-9160. DOI: 10.1016/0040-4039(94)88453-6  0.386
1993 Rodríguez J, Nieto RM, Crews P. New structures and bioactivity patterns of bengazole alkaloids from a choristid marine sponge. Journal of Natural Products. 56: 2034-40. PMID 8133293 DOI: 10.1021/Np50102A002  0.436
1993 Jiménez C, Crews P. 13C-NMR assignments and cytotoxicity assessment of zoanthoxanthin alkaloids from zoanthid corals. Journal of Natural Products. 56: 9-14. PMID 8095518 DOI: 10.1021/Np50091A002  0.397
1993 Alvi KA, Rodríguez J, Diaz MC, Moretti R, Wilhelm RS, Lee RH, Slate DL, Crews P. Protein tyrosine kinase inhibitory properties of planar polycyclics obtained from the marine sponge Xestospongia cf. carbonaria and from total synthesis Journal of Organic Chemistry. 58: 4871-4880. DOI: 10.1021/Jo00070A023  0.487
1993 Todd JS, Zimmerman RC, Crews P, Alberte RS. The antifouling activity of natural and synthetic phenolic acid sulphate esters Phytochemistry. 34: 401-404. DOI: 10.1016/0031-9422(93)80017-M  0.373
1992 Alvi KA, Crews P. Homoscalarane sesterterpenes from Lendenfeldia frondosa. Journal of Natural Products. 55: 859-65. PMID 1402955 DOI: 10.1021/Np50085A004  0.42
1992 Lee RH, Slate DL, Moretti R, Alvi KA, Crews P. Marine sponge polyketide inhibitors of protein tyrosine kinase. Biochemical and Biophysical Research Communications. 184: 765-72. PMID 1315532 DOI: 10.1016/0006-291X(92)90656-6  0.306
1992 Alvi KA, Diaz MC, Crews P, Slate DL, Lee RH, Moretti R. Evaluation of new sesquiterpene quinones from two Dysidea sponge species as inhibitors of protein tyrosine kinase Journal of Organic Chemistry. 57: 6604-6607. DOI: 10.1021/Jo00050A043  0.377
1992 Espada A, Jiménez C, Rodríguez J, Crews P, Riguera R. Sarasinosides D-G: four new triterpenoid saponins from the sponge asteropus sarasinosum Tetrahedron. 48: 8685-8696. DOI: 10.1016/S0040-4020(01)89444-8  0.471
1992 Rodríguez J, Quiñoá E, Riguera R, Peters BM, Abrell LM, Crews P. The structures and stereochemistry of cytotoxic sesquiterpene quinones from dactylospongia elegans Tetrahedron. 48: 6667-6680. DOI: 10.1016/S0040-4020(01)80012-0  0.511
1991 Alvi KA, Tenenbaum L, Crews P. Anthelmintic polyfunctional nitrogen-containing terpenoids from marine sponges. Journal of Natural Products. 54: 71-8. PMID 2045823 DOI: 10.1021/Np50073A002  0.37
1991 Alvi KA, Crews P, Loughhead DG. Structures and total synthesis of 2-aminoimidazoles from A Notodoris nudibranch Journal of Natural Products. 54: 1509-1515. DOI: 10.1021/Np50078A004  0.319
1991 Jiménez C, Crews P. Novel marine sponge derived amino acids 13. Additional psammaplin derivatives from Psammaplysilla purpurea Tetrahedron. 47: 2097-2102. DOI: 10.1016/S0040-4020(01)96120-4  0.44
1991 Crews P, Jiménez C, O'Neil-Johnson M. Using spectroscopic and database strategies to unravel structures of polycyclic bioactive marine sponge sesterterpenes Tetrahedron. 47: 3585-3600. DOI: 10.1016/S0040-4020(01)80872-3  0.441
1990 Jiménez C, Crews P. Novel marine sponge amino acids, 10. Xestoaminols from Xestospongia sp. Journal of Natural Products. 53: 978-82. PMID 1710256 DOI: 10.1021/Np50070A033  0.395
1990 Adamczeski M, Quinoa E, Crews P. Novel sponge-derived amino acids. 11. The entire absolute stereochemistry of the bengamides Journal of Organic Chemistry. 55: 240-242. DOI: 10.1021/Jo00288A039  0.316
1990 Inman WD, O'Neill-Johnson M, Crews P. Novel marine sponge alkaloids. 1. Plakinidine A and B, anthelmintic active alkaloids from a Plakortis sponge Journal of the American Chemical Society. 112: 1-4. DOI: 10.1021/Ja00157A001  0.378
1989 Adamczeski M, Quinoa E, Crews P. Novel sponge-derived amino acids. 5. Structures, stereochemistry, and synthesis of several new heterocycles Journal of the American Chemical Society. 111: 647-654. DOI: 10.1021/Ja00184A037  0.356
1988 Omar S, Albert C, Fanni T, Crews P. Polyfunctional diterpene isonitriles from marine sponge Acanthella carvenosa Journal of Organic Chemistry. 53: 5971-5972. DOI: 10.1021/Jo00260A034  0.373
1988 Quinoa E, Kakou Y, Crews P. Fijianolides, polyketide heterocycles from a marine sponge Journal of Organic Chemistry. 53: 3642-3644. DOI: 10.1021/Jo00250A052  0.401
1988 Manes LV, Crews P, Kernan MR, Faulkner DJ, Fronczek FR, Gandour RD. Chemistry and revised structure of suvanine The Journal of Organic Chemistry. 53: 570-575. DOI: 10.1021/Jo00238A017  0.311
1988 Adamczeski M, Quinoa E, Crews P. Unusual anthelminthic oxazoles from a marine sponge Journal of the American Chemical Society. 110: 1598-1602. DOI: 10.1021/Ja00213A037  0.366
1988 Quiñoà E, Crews P. Melynes, polyacetylene constituents from a vanuatu marine sponge Tetrahedron Letters. 29: 2037-2040. DOI: 10.1016/S0040-4039(00)87828-4  0.343
1987 Quiñoà E, Crews P. Phenolic constituents of Psammaplysilla Tetrahedron Letters. 28: 3229-3232. DOI: 10.1016/S0040-4039(00)95478-9  0.393
1987 Quiñoà E, Crews P. Niphatynes, methoxylamine pyridines from the marine sponge, niphates SP. Tetrahedron Letters. 28: 2467-2468. DOI: 10.1016/S0040-4039(00)95442-X  0.401
1986 Crews P, Bescansa P. Sesterterpenes from a common marine sponge, Hyrtios erecta. Journal of Natural Products. 49: 1041-52. PMID 3572416 DOI: 10.1021/Np50048A012  0.363
1986 Quinoa E, Adamczeski M, Crews P, Bakus GJ. Bengamides, heterocyclic anthelmintics from a Jaspidae marine sponge Journal of Organic Chemistry. 51: 4494-4497. DOI: 10.1021/Jo00373A036  0.385
1986 Quinoa E, Kho E, Manes LV, Crews P, Bakus GJ. Heterocycles from the marine sponge Xestospongia sp Journal of Organic Chemistry. 51: 4260-4264. DOI: 10.1021/Jo00372A029  0.302
1986 Crews P, Manes LV, Boehler M. Jasplakinolide, a cyclodepsipeptide from the marine sponge, Jaspis SP. Tetrahedron Letters. 27: 2797-2800. DOI: 10.1016/S0040-4039(00)84645-6  0.329
1985 Manes LV, Naylor S, Crews P, Bakus GJ. Suvanine, a novel sesterterpene from an Ircinia marine sponge Journal of Organic Chemistry. 50: 284-286. DOI: 10.1021/Jo00202A030  0.376
1985 Manes LV, Naylor S, Crews P, Bakus GJ. Suvanine, A Novel Sesterterpene From An Ircinia Marine Sponge Cheminform. 16. DOI: 10.1002/Chin.198525346  0.376
1984 Manes LV, Bakus GJ, Crews P. Bioactive marine sponge norditerpene and norsesterterpene peroxides Tetrahedron Letters. 25: 931-934. DOI: 10.1016/S0040-4039(01)80065-4  0.346
1984 Crews P, Myers BL, Naylor S, Clason EL, Jacobs RS, Staal GB. Bio-active monoterpenes from red seaweeds Phytochemistry. 23: 1449-1451. DOI: 10.1016/S0031-9422(00)80484-7  0.33
1982 Crews P, Klein TE, Hogue ER, Myers BL. Tricyclic diterpenes from the brown marine algae Dictyota divaricata and Dictyota linearis Journal of Organic Chemistry. 13: 811-815. DOI: 10.1021/Jo00344A012  0.36
1981 Selover SJ, Crews P, Tagle B, Clardy J. New diterpenes from the common Caribbean gorgonian Briareum asbestinum (Pallus) Journal of Organic Chemistry. 46: 964-970. DOI: 10.1021/Jo00318A023  0.326
1981 Selover SJ, Crews P, Tagle B, Clardy J. New Diterpenes From The Common Caribbean Gorgonian Briareum Asbestinum (Pallus) Cheminform. 12. DOI: 10.1002/Chin.198128346  0.326
1980 Selover SJ, Crews P. Kylinone, a new sesquiterpene skeleton from the marine alga Laurencia pacifica Journal of Organic Chemistry. 11: 69-72. DOI: 10.1021/Jo01289A015  0.371
1978 Crews P, Kho-Wiseman E. Stereochemical assignments in marine natural products by 13C NMR γ effects Tetrahedron Letters. 19: 2483-2486. DOI: 10.1016/S0040-4039(01)94806-3  0.328
1976 Crews P, Ng P, Kho-Wiseman E, Pace C. Halogenated monoterpenes of the red alga Microcladia Phytochemistry. 15: 1707-1711. DOI: 10.1016/S0031-9422(00)97461-2  0.328
1975 Crews P, Kho E. Plocamene B. New cyclic monoterpene skeleton from a red marine alga Journal of Organic Chemistry. 40: 2568-2570. DOI: 10.1021/Jo00905A048  0.366
1974 Crews P, Kho E. Cartilagineal. Unusual monoterpene aldehyde from marine alga Journal of Organic Chemistry. 39: 3303-3304. DOI: 10.1021/Jo00936A039  0.36
1971 Crews P, Loffgren M, Bertelli DJ. Cycloaddition reactions of benzyne with cyclic olefins Tetrahedron Letters. 12: 4697-4700. DOI: 10.1016/S0040-4039(01)97565-3  0.681
1968 Bertelli DJ, Crews P. The formation and reactivity of benzocyclobutenone anion Journal of the American Chemical Society. 90: 3889-3890. DOI: 10.1021/Ja01016A067  0.683
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