Daniel Lai - Publications

Affiliations: 
2014-2016 University of British Columbia, Vancouver, Vancouver, BC, Canada 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, ... ... Lai D, et al. Single-cell genomic variation induced by mutational processes in cancer. Nature. PMID 36289342 DOI: 10.1038/s41586-022-05249-0  0.329
2020 Cochrane DR, Campbell KR, Greening K, Ho GC, Hopkins J, Bui M, Douglas JM, Sharlandjieva V, Munzur AD, Lai D, DeGrood M, Gibbard EW, Leung S, Boyd N, Cheng AS, et al. Single cell transcriptomes of normal endometrial derived organoids uncover novel cell type markers and cryptic differentiation of primary tumours. The Journal of Pathology. PMID 32686114 DOI: 10.1002/Path.5511  0.362
2020 Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, ... ... Lai D, et al. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nature Medicine. PMID 32094924 DOI: 10.1038/S41591-020-0757-Z  0.384
2019 Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, et al. Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing. Cell. 179: 1207-1221.e22. PMID 31730858 DOI: 10.1016/J.Cell.2019.10.026  0.373
2019 O'Flanagan CH, Campbell KR, Zhang AW, Kabeer F, Lim JLP, Biele J, Eirew P, Lai D, McPherson A, Kong E, Bates C, Borkowski K, Wiens M, Hewitson B, Hopkins J, et al. Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses. Genome Biology. 20: 210. PMID 31623682 DOI: 10.1186/S13059-019-1830-0  0.343
2019 Zhang AW, O'Flanagan C, Chavez EA, Lim JLP, Ceglia N, McPherson A, Wiens M, Walters P, Chan T, Hewitson B, Lai D, Mottok A, Sarkozy C, Chong L, Aoki T, et al. Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling. Nature Methods. PMID 31501550 DOI: 10.1038/S41592-019-0529-1  0.397
2019 Campbell KR, Steif A, Laks E, Zahn H, Lai D, McPherson A, Farahani H, Kabeer F, O'Flanagan C, Biele J, Brimhall J, Wang B, Walters P, Consortium I, Bouchard-Côté A, et al. clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers. Genome Biology. 20: 54. PMID 30866997 DOI: 10.1186/S13059-019-1645-Z  0.416
2019 Ennishi D, Takata K, Beguelin W, Duns G, Mottok A, Farinha P, Bashashati A, Saberi S, Boyle M, Meissner B, Ben-Neriah S, Woolcock BW, Telenius A, Lai D, Teater M, et al. Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition. Cancer Discovery. PMID 30705065 DOI: 10.1158/2159-8290.Cd-18-1090  0.363
2019 Pilsworth JA, Cochrane DR, Neilson S, Färkkilä AEM, Horlings HM, Yanagida S, Senz J, Wang YK, Moussavi B, Lai D, Bashashati A, Keul J, Wong A, Meurs Hv, Brucker SY, et al. Abstract GMM-047: GENOMIC CHARACTERIZATION OF ADULT-TYPE GRANULOSA CELL TUMORS: IMPLICATIONS FOR PATHOGENESIS AND TREATMENT OF RECURRENT DISEASE Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Gmm-047  0.373
2019 Healy S, Ennishi D, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, Vigano E, ... ... Lai D, et al. Abstract 3480:TMEM30Aloss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma Cancer Research. 79: 3480-3480. DOI: 10.1158/1538-7445.Am2019-3480  0.397
2018 Arthur SE, Jiang A, Grande BM, Alcaide M, Cojocaru R, Rushton CK, Mottok A, Hilton LK, Lat PK, Zhao EY, Culibrk L, Ennishi D, Jessa S, Chong L, Thomas N, ... ... Lai D, et al. Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma. Nature Communications. 9: 4001. PMID 30275490 DOI: 10.1038/S41467-018-06354-3  0.39
2018 Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, ... ... Lai D, et al. Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer. Cell. PMID 29754820 DOI: 10.1016/J.Cell.2018.03.073  0.382
2018 Ennishi D, Takata K, Béguelin W, Duns G, Mottok A, Farinha P, Bashashati A, Scott D, Boyle M, Meissner B, Ben-Neriah S, Woolcock BW, Telenius A, Lai D, Teater MR, et al. Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma Blood. 132: 1560-1560. DOI: 10.1182/Blood-2018-99-112010  0.345
2017 Farahani H, de Souza CPE, Billings R, Yap D, Shumansky K, Wan A, Lai D, Mes-Masson AM, Aparicio S, P Shah S. Engineered in-vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer. Scientific Reports. 7: 13467. PMID 29044127 DOI: 10.1038/S41598-017-13338-8  0.347
2017 Wang YK, Bashashati A, Anglesio MS, Cochrane DR, Grewal DS, Ha G, McPherson A, Horlings HM, Senz J, Prentice LM, Karnezis AN, Lai D, Aniba MR, Zhang AW, Shumansky K, et al. Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes. Nature Genetics. PMID 28436987 DOI: 10.1038/Ng.3849  0.385
2017 Ennishi D, Mottok A, Ben-Neriah S, Shulha HP, Farinha P, Chan FC, Meissner B, Boyle M, Hother C, Kridel R, Lai D, Saberi S, Bashashati A, Shah SP, Morin RD, et al. Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell of origin-specific clinical impact. Blood. PMID 28351934 DOI: 10.1182/Blood-2016-11-747022  0.341
2016 Leung K, Klaus A, Lin BK, Laks E, Biele J, Lai D, Bashashati A, Huang YF, Aniba R, Moksa M, Steif A, Mes-Masson AM, Hirst M, Shah SP, Aparicio S, et al. Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates. Proceedings of the National Academy of Sciences of the United States of America. PMID 27412862 DOI: 10.1073/Pnas.1520964113  0.374
2015 Lai D, Meyer IM. A comprehensive comparison of general RNA-RNA interaction prediction methods. Nucleic Acids Research. PMID 26673718 DOI: 10.1093/Nar/Gkv1477  0.307
2014 Lai D, Meyer IM. e-RNA: a collection of web servers for comparative RNA structure prediction and visualisation. Nucleic Acids Research. 42: W373-6. PMID 24810851 DOI: 10.1093/Nar/Gku292  0.313
2012 Ha G, Roth A, Lai D, Bashashati A, Ding J, Goya R, Giuliany R, Rosner J, Oloumi A, Shumansky K, Chin SF, Turashvili G, Hirst M, Caldas C, Marra MA, et al. Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer. Genome Research. 22: 1995-2007. PMID 22637570 DOI: 10.1101/Gr.137570.112  0.408
2012 Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, ... ... Lai D, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature. 486: 395-9. PMID 22495314 DOI: 10.1038/Nature10933  0.375
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