Christopher G Ellis - Publications

Affiliations: 
Medical Biophysics University of Western Ontario, London, Ontario, Canada 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mawdsley L, Eskandari R, Kamar F, Rajaram A, Yip LCM, Abayomi N, Milkovich S, Carson JJL, St Lawrence K, Ellis CG, Diop M. In vivo optical assessment of cerebral and skeletal muscle microvascular response to phenylephrine. Faseb Bioadvances. 6: 390-399. PMID 39399479 DOI: 10.1096/fba.2024-00063  0.38
2022 Kowalewska PM, Piazza JE, Milkovich SL, Sové RJ, Wang L, Whitehead SN, Ellis CG. Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model. Scientific Reports. 12: 6339. PMID 35428849 DOI: 10.1038/s41598-022-10208-w  0.757
2022 Christie JR, Kong I, Mawdsley L, Milkovich S, Doornekamp A, Baek J, Fraser GM, Ellis CG, Sové RJ. Optical method to determine in vivo capillary hematocrit, hemoglobin concentration, and 3-D network geometry in skeletal muscle. Microcirculation (New York, N.Y. : 1994). e12751. PMID 35146836 DOI: 10.1111/micc.12751  0.729
2022 Mendelson AA, Ho E, Scott S, Vijay R, Hunter T, Milkovich S, Ellis CG, Goldman D. Capillary module hemodynamics and mechanisms of blood flow regulation in skeletal muscle capillary networks: Experimental and computational analysis. The Journal of Physiology. PMID 35067970 DOI: 10.1113/JP282342  0.306
2021 Sové RJ, Milkovich S, Nikolov HN, Holdsworth DW, Ellis CG, Fraser GM. Localized Oxygen Exchange Platform for Intravital Video Microscopy Investigations of Microvascular Oxygen Regulation. Frontiers in Physiology. 12: 654928. PMID 34168569 DOI: 10.3389/fphys.2021.654928  0.766
2021 Ghonaim NW, Fraser GM, Goldman D, Milkovich S, Yang J, Ellis CG. Evidence for Role of Capillaries in Regulation of Skeletal Muscle Oxygen Supply. Microcirculation (New York, N.Y. : 1994). e12699. PMID 33853202 DOI: 10.1111/micc.12699  0.799
2021 Mendelson AA, Lansdell C, Fox-Robichaud AE, Liaw P, Arora J, Cailhier JF, Cepinskas G, Charbonney E, Dos Santos C, Dwivedi D, Ellis CG, Fergusson D, Fiest K, Gill SE, Hendrick K, et al. National Preclinical Sepsis Platform: developing a framework for accelerating innovation in Canadian sepsis research. Intensive Care Medicine Experimental. 9: 14. PMID 33738642 DOI: 10.1186/s40635-020-00366-4  0.587
2021 Mendelson AA, Milkovich S, Hunter T, Vijay R, Choi YH, Milkovich S, Ho E, Goldman D, Ellis CG. The Capillary Fascicle in skeletal muscle: structural and functional physiology of RBC distribution in capillary networks. The Journal of Physiology. PMID 33595111 DOI: 10.1113/JP281172  0.426
2020 Mendelson AA, Rajaram A, Bainbridge D, Lawrence KS, Bentall T, Sharpe M, Diop M, Ellis CG. Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study. Journal of Clinical Monitoring and Computing. PMID 33104968 DOI: 10.1007/s10877-020-00611-x  0.315
2020 McClatchey PM, Williams IM, Xu Z, Mignemi NA, Hughey CC, McGuinness OP, Beckman JA, Wasserman DH, Poole DC, Akerstrom T, Goldman D, Fraser GM, Ellis CG. Reply to Letter to the Editor: Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo. American Journal of Physiology. Endocrinology and Metabolism. 318: E313-E317. PMID 32068464 DOI: 10.1152/Ajpendo.00508.2019  0.743
2020 Nwadozi E, Rudnicki M, De Ciantis M, Milkovich S, Pulbere A, Roudier E, Birot O, Gustafsson T, Ellis CG, Haas TL. High fat diet pre-conditioning improves microvascular remodeling during regeneration of ischemic mouse skeletal muscle. Acta Physiologica (Oxford, England). PMID 32012450 DOI: 10.1111/apha.13449  0.297
2019 Akerstrom T, Goldman D, Nilsson F, Milkovich SL, Fraser GM, Brand CL, Hellsten Y, Ellis CG. Hyperinsulinaemia does not cause de novo capillary recruitment in rat skeletal muscle. Microcirculation (New York, N.Y. : 1994). PMID 31605649 DOI: 10.1111/micc.12593  0.768
2019 Rudziak P, Ellis CG, Kowalewska PM. Role and Molecular Mechanisms of Pericytes in Regulation of Leukocyte Diapedesis in Inflamed Tissues. Mediators of Inflammation. 2019: 4123605. PMID 31205449 DOI: 10.1155/2019/4123605  0.303
2018 Sové RJ, Drakos NE, Fraser GM, Ellis CG. Using digital inpainting to estimate incident light intensity for the calculation of red blood cell oxygen saturation from microscopy images. Journal of Biophotonics. e201800103. PMID 29797788 DOI: 10.1002/Jbio.201800103  0.731
2018 O'Neil MP, Alie R, Guo LR, Myers ML, Murkin J, Ellis C. Microvascular Responsiveness to Pulsatile and Non-Pulsatile Flow during Cardiopulmonary Bypass. The Annals of Thoracic Surgery. PMID 29391150 DOI: 10.1016/j.athoracsur.2018.01.007  0.319
2017 Bateman RM, Sharpe MD, Singer M, Ellis CG. The Effect of Sepsis on the Erythrocyte. International Journal of Molecular Sciences. 18. PMID 28885563 DOI: 10.3390/ijms18091932  0.319
2017 Arpino JM, Nong Z, Li F, Yin H, Ghonaim NW, Milkovich S, Balint B, O'Neil C, Fraser GM, Goldman D, Ellis CG, Pickering JG. 4D Microvascular Analysis Reveals that Regenerative Angiogenesis in Ischemic Muscle Produces a Flawed Microcirculation. Circulation Research. PMID 28174322 DOI: 10.1161/CIRCRESAHA.116.310535  0.766
2017 Mason McClatchey P, Wu F, Olfert IM, Ellis CG, Goldman D, Reusch JE, Frisbee JC. Impaired Tissue Oxygenation in Metabolic Syndrome Requires Increased Microvascular Perfusion Heterogeneity. Journal of Cardiovascular Translational Research. PMID 28168652 DOI: 10.1007/s12265-017-9732-6  0.451
2016 Sové RJ, Fraser GM, Goldman D, Ellis CG. Finite Element Model of Oxygen Transport for the Design of Geometrically Complex Microfluidic Devices Used in Biological Studies. Plos One. 11: e0166289. PMID 27829071 DOI: 10.1371/journal.pone.0166289  0.754
2016 Secor D, Swarbreck S, Ellis CG, Sharpe MD, Feng Q, Tyml K. Ascorbate inhibits platelet-endothelial adhesion in an in-vitro model of sepsis via reduced endothelial surface P-selectin expression. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. PMID 26829365 DOI: 10.1097/Mbc.0000000000000528  0.246
2015 Bateman RM, Sharpe MD, Jagger JE, Ellis CG. Sepsis impairs microvascular autoregulation and delays capillary response within hypoxic capillaries. Critical Care (London, England). 19: 389. PMID 26537126 DOI: 10.1186/s13054-015-1102-7  0.435
2015 Ellsworth ML, Ellis CG, Sprague RS. Role of erythrocyte-released ATP in the regulation of microvascular oxygen supply in skeletal muscle. Acta Physiologica (Oxford, England). PMID 26336065 DOI: 10.1111/apha.12596  0.479
2015 Yin H, Frontini MJ, Arpino JM, Nong Z, O'Neil C, Xu Y, Balint B, Ward AD, Chakrabarti S, Ellis CG, Gros R, Pickering JG. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. The Journal of Biological Chemistry. PMID 26183774 DOI: 10.1074/jbc.M115.652222  0.257
2015 Fraser GM, Sharpe MD, Goldman D, Ellis CG. Impact of Incremental Perfusion Loss on Oxygen Transport in a Capillary Network Mathematical Model. Microcirculation (New York, N.Y. : 1994). 22: 348-59. PMID 25817391 DOI: 10.1111/micc.12202  0.789
2015 Swarbreck SB, Secor D, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Effect of ascorbate on plasminogen activator inhibitor-1 expression and release from platelets and endothelial cells in an in-vitro model of sepsis. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 26: 436-42. PMID 25730478 DOI: 10.1097/Mbc.0000000000000273  0.263
2014 Swarbreck S, Secor D, Li F, Gross PL, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Effect of ascorbate on fibrinolytic factors in septic mouse skeletal muscle. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 25: 745-53. PMID 24824492 DOI: 10.1097/Mbc.0000000000000138  0.367
2014 Swarbreck SB, Secor D, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Short-term effect of ascorbate on bacterial content, plasminogen activator inhibitor-1, and myeloperoxidase in septic mice. The Journal of Surgical Research. 191: 432-40. PMID 24814200 DOI: 10.1016/J.Jss.2014.04.017  0.293
2013 Sove RJ, Ghonaim N, Goldman D, Ellis CG. A computational model of a microfluidic device to measure the dynamics of oxygen-dependent ATP release from erythrocytes. Plos One. 8: e81537. PMID 24312316 DOI: 10.1371/journal.pone.0081537  0.777
2013 Ghonaim NW, Fraser GM, Ellis CG, Yang J, Goldman D. Modeling steady state SO2-dependent changes in capillary ATP concentration using novel O2 micro-delivery methods. Frontiers in Physiology. 4: 260. PMID 24069001 DOI: 10.3389/fphys.2013.00260  0.765
2013 Fraser GM, Goldman D, Ellis CG. Comparison of generated parallel capillary arrays to three-dimensional reconstructed capillary networks in modeling oxygen transport in discrete microvascular volumes. Microcirculation (New York, N.Y. : 1994). 20: 748-63. PMID 23841679 DOI: 10.1111/micc.12075  0.783
2013 Nyberg M, Al-Khazraji BK, Mortensen SP, Jackson DN, Ellis CG, Hellsten Y. Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305: R281-90. PMID 23761642 DOI: 10.1152/ajpregu.00189.2013  0.301
2012 Goldman D, Fraser GM, Ellis CG, Sprague RS, Ellsworth ML, Stephenson AH. Toward a multiscale description of microvascular flow regulation: o(2)-dependent release of ATP from human erythrocytes and the distribution of ATP in capillary networks. Frontiers in Physiology. 3: 246. PMID 22934004 DOI: 10.3389/fphys.2012.00246  0.772
2012 Ellis CG, Milkovich S, Goldman D. What is the efficiency of ATP signaling from erythrocytes to regulate distribution of O(2) supply within the microvasculature? Microcirculation (New York, N.Y. : 1994). 19: 440-50. PMID 22587367 DOI: 10.1111/j.1549-8719.2012.00196.x  0.388
2012 Fraser GM, Goldman D, Ellis CG. Microvascular flow modeling using in vivo hemodynamic measurements in reconstructed 3D capillary networks. Microcirculation (New York, N.Y. : 1994). 19: 510-20. PMID 22429386 DOI: 10.1111/j.1549-8719.2012.00178.x  0.768
2012 Fraser GM, Milkovich S, Goldman D, Ellis CG. Mapping 3-D functional capillary geometry in rat skeletal muscle in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 302: H654-64. PMID 22140042 DOI: 10.1152/ajpheart.01185.2010  0.784
2011 Ghonaim NW, Lau LW, Goldman D, Ellis CG, Yang J. A micro-delivery approach for studying microvascular responses to localized oxygen delivery. Microcirculation (New York, N.Y. : 1994). 18: 646-54. PMID 21914035 DOI: 10.1111/j.1549-8719.2011.00132.x  0.457
2011 Frontini MJ, Nong Z, Gros R, Drangova M, O'Neil C, Rahman MN, Akawi O, Yin H, Ellis CG, Pickering JG. Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells. Nature Biotechnology. 29: 421-7. PMID 21499246 DOI: 10.1038/Nbt.1845  0.348
2011 Moschandreou TE, Ellis CG, Goldman D. Influence of tissue metabolism and capillary oxygen supply on arteriolar oxygen transport: a computational model. Mathematical Biosciences. 232: 1-10. PMID 21439980 DOI: 10.1016/j.mbs.2011.03.010  0.426
2010 Moschandreou TE, Ellis CG, Goldman D. Mass Transfer in a Rigid Tube With Pulsatile Flow and Constant Wall Concentration. Journal of Fluids Engineering. 132: 81202. PMID 21603585 DOI: 10.1115/1.4002213  0.251
2010 Jackson DN, Ellis CG, Shoemaker JK. Estrogen modulates the contribution of neuropeptide Y to baseline hindlimb blood flow control in female Sprague-Dawley rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R1351-7. PMID 20219870 DOI: 10.1152/ajpregu.00420.2009  0.328
2010 Ellis CG, Goldman D, Hanson M, Stephenson AH, Milkovich S, Benlamri A, Ellsworth ML, Sprague RS. Defects in oxygen supply to skeletal muscle of prediabetic ZDF rats. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1661-70. PMID 20207810 DOI: 10.1152/ajpheart.01239.2009  0.419
2009 Chin-Yee IH, Gray-Statchuk L, Milkovich S, Ellis CG. Transfusion of stored red blood cells adhere in the rat microvasculature. Transfusion. 49: 2304-10. PMID 19624601 DOI: 10.1111/j.1537-2995.2009.02315.x  0.385
2009 Ellsworth ML, Ellis CG, Goldman D, Stephenson AH, Dietrich HH, Sprague RS. Erythrocytes: oxygen sensors and modulators of vascular tone. Physiology (Bethesda, Md.). 24: 107-16. PMID 19364913 DOI: 10.1152/physiol.00038.2008  0.33
2008 Bateman RM, Sharpe MD, Goldman D, Lidington D, Ellis CG. Inhibiting nitric oxide overproduction during hypotensive sepsis increases local oxygen consumption in rat skeletal muscle. Critical Care Medicine. 36: 225-31. PMID 18090362 DOI: 10.1097/01.Ccm.0000295307.92027.2F  0.501
2006 Goldman D, Bateman RM, Ellis CG. Effect of decreased O2 supply on skeletal muscle oxygenation and O2 consumption during sepsis: role of heterogeneous capillary spacing and blood flow. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2277-85. PMID 16399873 DOI: 10.1152/ajpheart.00547.2005  0.32
2005 Ellis CG, Jagger J, Sharpe M. The microcirculation as a functional system. Critical Care (London, England). S3-8. PMID 16168072 DOI: 10.1186/cc3751  0.44
2005 Japee SA, Pittman RN, Ellis CG. Automated method for tracking individual red blood cells within capillaries to compute velocity and oxygen saturation. Microcirculation (New York, N.Y. : 1994). 12: 507-15. PMID 16147467 DOI: 10.1080/10739680591003341  0.306
2005 Japee SA, Pittman RN, Ellis CG. A new video image analysis system to study red blood cell dynamics and oxygenation in capillary networks. Microcirculation (New York, N.Y. : 1994). 12: 489-506. PMID 16147466 DOI: 10.1080/10739680591003332  0.392
2005 Varghese HJ, Mackenzie LT, Groom AC, Ellis CG, Ryan A, MacDonald IC, Chambers AF. In vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model. Angiogenesis. 7: 157-64. PMID 15516836 DOI: 10.1007/s10456-004-1941-3  0.284
2004 Varghese HJ, MacKenzie LT, Groom AC, Ellis CG, Chambers AF, MacDonald IC. Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy. American Journal of Physiology. Heart and Circulatory Physiology. 288: H185-93. PMID 15388500 DOI: 10.1152/AJPHEART.01022.2003  0.337
2004 Goldman D, Bateman RM, Ellis CG. Effect of sepsis on skeletal muscle oxygen consumption and tissue oxygenation: interpreting capillary oxygen transport data using a mathematical model. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2535-44. PMID 15319199 DOI: 10.1152/ajpheart.00889.2003  0.387
2003 Bateman RM, Sharpe MD, Ellis CG. Bench-to-bedside review: microvascular dysfunction in sepsis--hemodynamics, oxygen transport, and nitric oxide. Critical Care (London, England). 7: 359-73. PMID 12974969 DOI: 10.1186/cc2353  0.488
2003 Filion RJ, Ellis CG. A finite difference model of O2 transport in aortic valve cusps: importance of intrinsic microcirculation. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2099-104. PMID 12869378 DOI: 10.1152/ajpheart.00330.2003  0.377
2002 Weind KL, Ellis CG, Boughner DR. Aortic valve cusp vessel density: relationship with tissue thickness. The Journal of Thoracic and Cardiovascular Surgery. 123: 333-40. PMID 11828294 DOI: 10.1067/MTC.2002.119696  0.298
2001 Jagger JE, Ellis CG, Sibbald WJ, Eichelbrönner O. Measurement temperature plays a pivotal role in the distribution of erythrocyte deformability after LPS. Biorheology. 38: 439-48. PMID 12016326  0.307
2001 Bateman RM, Jagger JE, Sharpe MD, Ellsworth ML, Mehta S, Ellis CG. Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis. American Journal of Physiology. Heart and Circulatory Physiology. 280: H2848-56. PMID 11356644 DOI: 10.1152/AJPHEART.2001.280.6.H2848  0.311
2001 Jagger JE, Bateman RM, Ellsworth ML, Ellis CG. Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenation. American Journal of Physiology. Heart and Circulatory Physiology. 280: H2833-9. PMID 11356642 DOI: 10.1152/ajpheart.2001.280.6.H2833  0.404
1999 Bloos F, Martin CM, Ellis CG, Sibbald WJ. Effects of modest anemia on systemic and coronary circulation of septic sheep. The American Journal of Physiology. 277: H2195-204. PMID 10600837 DOI: 10.1152/ajpheart.1999.277.6.H2195  0.332
1999 Eichelbrönner O, Sielenkämper A, D'Almeida M, Ellis CG, Sibbald WJ, Chin-Yee IH. Effects of FI(O(2)) on hemodynamic responses and O(2) transport during RSR13-induced reduction in P(50). The American Journal of Physiology. 277: H290-8. PMID 10409208  0.279
1997 Pickering JG, Uniyal S, Ford CM, Chau T, Laurin MA, Chow LH, Ellis CG, Fish J, Chan BM. Fibroblast growth factor-2 potentiates vascular smooth muscle cell migration to platelet-derived growth factor: upregulation of alpha2beta1 integrin and disassembly of actin filaments. Circulation Research. 80: 627-37. PMID 9130443 DOI: 10.1161/01.Res.80.5.627  0.273
1995 Groom AC, Ellis CG, Wrigley SJ, Potter RF. Capillary network morphology and capillary flow. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 15: 223-30. PMID 8852619 DOI: 10.1159/000179022  0.409
1994 Ellsworth ML, Ellis CG, Popel AS, Pittman RN. Role of Microvessels in Oxygen Supply to Tissue. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 9: 119-123. PMID 29209101 DOI: 10.1152/Physiologyonline.1994.9.3.119  0.578
1994 Ellis CG, Wrigley SM, Groom AC. Heterogeneity of red blood cell perfusion in capillary networks supplied by a single arteriole in resting skeletal muscle. Circulation Research. 75: 357-68. PMID 8033345 DOI: 10.1161/01.res.75.2.357  0.418
1994 Potter RF, Ellis CG, Tyml K, Groom AC. Effect of superoxide dismutase and 21-aminosteroids (lazaroids) on microvascular perfusion following ischemia-reperfusion in skeletal muscle. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 14: 313-8. PMID 7635646 DOI: 10.1159/000178849  0.379
1993 Potter RF, Dietrich HH, Tyml K, Ellis CG, Cronkwright J, Groom AC. Ischemia-reperfusion induced microvascular dysfunction in skeletal muscle: application of intravital video microscopy. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 13: 173-86. PMID 8125707  0.378
1992 Ellis CG, Ellsworth ML, Pittman RN, Burgess WL. Application of image analysis for evaluation of red blood cell dynamics in capillaries. Microvascular Research. 44: 214-25. PMID 1474928 DOI: 10.1016/0026-2862(92)90081-Y  0.387
1990 Ellis CG, Mathieu-Costello O, Potter RF, MacDonald IC, Groom AC. Effect of sarcomere length on total capillary length in skeletal muscle: in vivo evidence for longitudinal stretching of capillaries. Microvascular Research. 40: 63-72. PMID 2398830 DOI: 10.1016/0026-2862(90)90008-F  0.374
1990 Ellis CG, Ellsworth ML, Pittman RN. Determination of red blood cell oxygenation in vivo by dual video densitometric image analysis. The American Journal of Physiology. 258: H1216-23. PMID 2331009  0.442
1990 Ellis CG, Wrigley SM, Potter RF, Groom AC. Temporal distributions of red cell supply rate to individual capillaries of resting skeletal muscle, in frog and rat. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 9: 67-84. PMID 2323898  0.404
1989 Tyml K, Ellis CG. Localized Heterogeneity of Red Cell Velocity in Skeletal Muscle at Rest and After Contraction Advances in Experimental Medicine and Biology. 248: 735-743. PMID 2789469 DOI: 10.1007/978-1-4684-5643-1_83  0.454
1989 Ellis CG, Tyml K, Strang BK. Variation in axial velocity profile of red cells passing through a single capillary. Advances in Experimental Medicine and Biology. 248: 543-550. PMID 2782173 DOI: 10.1007/978-1-4684-5643-1_60  0.301
1979 Schneiderman G, Ellis CG, Goldstick TK. Mass transport to walls of stenosed arteries: variation with Reynolds number and blood flow separation. Journal of Biomechanics. 12: 869-77. PMID 500744 DOI: 10.1016/0021-9290(79)90172-6  0.736
Show low-probability matches.