Year |
Citation |
Score |
2023 |
Liu X, Wang Y, Weng Z, Xu Q, Zhou C, Tang J, Chen XZ. Inhibition of TRPP3 by calmodulin through Ca/calmodulin-dependent protein kinase II. Cell Insight. 2: 100088. PMID 37193065 DOI: 10.1016/j.cellin.2023.100088 |
0.364 |
|
2023 |
Cai R, Chen XZ. Roles of Intramolecular Interactions in the Regulation of TRP Channels. Reviews of Physiology, Biochemistry and Pharmacology. 186: 29-56. PMID 35882668 DOI: 10.1007/112_2022_74 |
0.791 |
|
2022 |
Liu X, Zhang R, Fatehi M, Wang Y, Long W, Tian R, Deng X, Weng Z, Xu Q, Light PE, Tang J, Chen XZ. Regulation of the PKD2 channel function by TACAN. The Journal of Physiology. PMID 36420836 DOI: 10.1113/JP283895 |
0.433 |
|
2022 |
Wang L, Cai R, Chen XZ, Peng JB. Molecular insights into the structural and dynamical changes of calcium channel TRPV6 induced by its interaction with phosphatidylinositol 4,5-bisphosphate. Journal of Biomolecular Structure & Dynamics. 1-10. PMID 35950523 DOI: 10.1080/07391102.2022.2109752 |
0.772 |
|
2022 |
Ahmed KT, Amin MR, Razmara P, Roy B, Cai R, Tang J, Chen XZ, Ali DW. Expression and development of TARP γ-4 in embryonic zebrafish. Developmental Neuroscience. PMID 35728564 DOI: 10.1159/000525578 |
0.697 |
|
2022 |
Huang Y, Li S, Liu Q, Wang Z, Li S, Liu L, Zhao W, Wang K, Zhang R, Wang L, Wang M, William Ali D, Michalak M, Chen XZ, Zhou C, et al. The LCK-14-3-3ζ-TRPM8 axis regulates TRPM8 function/assembly and promotes pancreatic cancer malignancy. Cell Death & Disease. 13: 524. PMID 35665750 DOI: 10.1038/s41419-022-04977-5 |
0.426 |
|
2021 |
Cai R, Tang J, Chen XZ. Ion permeation controlled by hydrophobic residues and proton binding in the proton-activated chloride channel. Iscience. 24: 103395. PMID 34825147 DOI: 10.1016/j.isci.2021.103395 |
0.746 |
|
2021 |
Cai R, Wang L, Liu X, Michalak M, Tang J, Peng JB, Chen XZ. Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion. Communications Biology. 4: 990. PMID 34413465 DOI: 10.1038/s42003-021-02521-3 |
0.75 |
|
2020 |
Huang Y, Li S, Jia Z, Zhao W, Zhou C, Zhang R, Ali DW, Michalak M, Chen XZ, Tang J. Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy. Frontiers in Oncology. 10: 573127. PMID 33344232 DOI: 10.3389/fonc.2020.573127 |
0.352 |
|
2020 |
Huang Y, Li S, Jia Z, Li S, He W, Zhou C, Zhang R, Xu R, Sun B, Ali DW, Michalak M, Chen XZ, Tang J. TRIM4 interacts with TRPM8 and regulates its channel function through K423-mediated ubiquitination. Journal of Cellular Physiology. PMID 33037615 DOI: 10.1002/jcp.30065 |
0.427 |
|
2020 |
Cai R, Liu X, Zhang R, Hofmann L, Zheng W, Amin MR, Wang L, Hu Q, Peng JB, Michalak M, Flockerzi V, Ali DW, Chen XZ, Tang J. Autoinhibition of TRPV6 Channel and Regulation by PIP2. Iscience. 23: 101444. PMID 32829285 DOI: 10.1016/J.Isci.2020.101444 |
0.783 |
|
2019 |
Wang Z, Ng C, Liu X, Wang Y, Li B, Kashyap P, Chaudhry HA, Castro A, Kalontar EM, Ilyayev L, Walker R, Alexander RT, Qian F, Chen XZ, Yu Y. The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex. Embo Reports. e48336. PMID 31441214 DOI: 10.15252/Embr.201948336 |
0.488 |
|
2019 |
Wang L, Jiang C, Cai R, Chen XZ, Peng JB. Unveiling the distinct mechanisms by which disease-causing mutations in the Kelch domain of KLHL3 disrupt the interaction with the acidic motif of WNK4 through molecular dynamics simulation. Biochemistry. PMID 30931564 DOI: 10.1021/acs.biochem.9b00066 |
0.712 |
|
2019 |
Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkley D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ. Author Correction: Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nature Communications. 10: 1452. PMID 30914650 DOI: 10.1038/S41467-019-09422-4 |
0.727 |
|
2018 |
Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkey D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nature Communications. 9: 2302. PMID 29899465 DOI: 10.1038/S41467-018-04586-X |
0.786 |
|
2018 |
Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, ... Chen XZ, et al. Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2. Cell Reports. 22: 1560-1573. PMID 29425510 DOI: 10.1016/J.Celrep.2018.01.042 |
0.781 |
|
2017 |
Zheng W, Hu R, Cai R, Hofmann L, Hu Q, Fatehi M, Long W, Kong T, Tang J, Light P, Flockerzi V, Cao Y, Chen XZ. Identification and characterization of hydrophobic gate residues in TRP channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28970257 DOI: 10.1096/fj.201700599RR |
0.782 |
|
2017 |
Hofmann L, Wang H, Zheng W, Philipp SE, Hidalgo P, Cavalié A, Chen XZ, Beck A, Flockerzi V. The S4---S5 linker - gearbox of TRP channel gating. Cell Calcium. PMID 28416203 DOI: 10.1016/j.ceca.2017.04.002 |
0.514 |
|
2016 |
Zheng W, Yang J, Beauchamp E, Cai R, Hussein S, Hofmann L, Li Q, Flockerzi V, Berthiaume LG, Tang J, Chen XZ. Regulation of TRPP3 channel function by N-terminal domain palmitoylation and phosphorylation. The Journal of Biological Chemistry. PMID 27754867 DOI: 10.1074/Jbc.M116.756544 |
0.772 |
|
2015 |
Hussein S, Zheng W, Dyte C, Wang Q, Yang J, Zhang F, Tang J, Cao Y, Chen XZ. Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca(2.). Scientific Reports. 5: 15752. PMID 26502994 DOI: 10.1038/srep15752 |
0.306 |
|
2015 |
Schorr S, Klein MC, Gamayun I, Melnyk A, Jung M, Schäuble N, Wang Q, Hemmis B, Bochen F, Greiner M, Lampel P, Urban SK, Hassdenteufel S, Dudek J, Chen XZ, et al. Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum. The Journal of Biological Chemistry. 290: 18621-35. PMID 26085089 DOI: 10.1074/jbc.M115.636639 |
0.391 |
|
2015 |
Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Zeng H, Tang J, Chen XZ. A novel PKD2L1 C-terminal domain critical for trimerization and channel function. Scientific Reports. 5: 9460. PMID 25820328 DOI: 10.1038/Srep09460 |
0.499 |
|
2012 |
Wang Q, Dai XQ, Li Q, Tuli J, Liang G, Li SS, Chen XZ. Filamin interacts with epithelial sodium channel and inhibits its channel function. The Journal of Biological Chemistry. 288: 264-73. PMID 23161538 DOI: 10.1074/jbc.M112.396408 |
0.482 |
|
2012 |
Wang Q, Dai XQ, Li Q, Wang Z, Cantero Mdel R, Li S, Shen J, Tu JC, Cantiello H, Chen XZ. Structural interaction and functional regulation of polycystin-2 by filamin. Plos One. 7: e40448. PMID 22802962 DOI: 10.1371/Journal.Pone.0040448 |
0.523 |
|
2011 |
Yang J, Wang Q, Zheng W, Tuli J, Li Q, Wu Y, Hussein S, Dai XQ, Shafiei S, Li XG, Shen PY, Tu JC, Chen XZ. Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction. The Journal of Biological Chemistry. 287: 6551-61. PMID 22174419 DOI: 10.1074/jbc.M111.305854 |
0.517 |
|
2009 |
Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J. Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 11558-63. PMID 19556541 DOI: 10.1073/Pnas.0903684106 |
0.301 |
|
2009 |
Raychowdhury MK, Ramos AJ, Zhang P, McLaughin M, Dai XQ, Chen XZ, Montalbetti N, Del Rocío Cantero M, Ausiello DA, Cantiello HF. Vasopressin receptor-mediated functional signaling pathway in primary cilia of renal epithelial cells. American Journal of Physiology. Renal Physiology. 296: F87-97. PMID 18945824 DOI: 10.1152/Ajprenal.90509.2008 |
0.315 |
|
2008 |
Chen XZ, Li Q, Wu Y, Liang G, Lara CJ, Cantiello HF. Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton. The Febs Journal. 275: 4675-83. PMID 18754774 DOI: 10.1111/j.1742-4658.2008.06616.x |
0.334 |
|
2008 |
Liang G, Li Q, Tang Y, Kokame K, Kikuchi T, Wu G, Chen XZ. Polycystin-2 is regulated by endoplasmic reticulum-associated degradation. Human Molecular Genetics. 17: 1109-19. PMID 18178578 DOI: 10.1093/hmg/ddm383 |
0.304 |
|
2007 |
Cantiello HF, Montalbetti N, Li Q, Chen XZ. The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism: Lessons from Polycystin-2 (TRPP2). Current Topics in Membranes. 59: 233-96. PMID 25168140 DOI: 10.1016/S1063-5823(06)59010-6 |
0.481 |
|
2007 |
Li Q, Dai XQ, Shen PY, Wu Y, Long W, Chen CX, Hussain Z, Wang S, Chen XZ. Direct binding of alpha-actinin enhances TRPP3 channel activity. Journal of Neurochemistry. 103: 2391-400. PMID 17944866 DOI: 10.1111/j.1471-4159.2007.04940.x |
0.35 |
|
2007 |
Dai XQ, Ramji A, Liu Y, Li Q, Karpinski E, Chen XZ. Inhibition of TRPP3 channel by amiloride and analogs. Molecular Pharmacology. 72: 1576-85. PMID 17804601 DOI: 10.1124/mol.107.037150 |
0.388 |
|
2007 |
Montalbetti N, Li Q, Wu Y, Chen XZ, Cantiello HF. Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures. The Journal of Physiology. 579: 717-28. PMID 17204494 DOI: 10.1113/jphysiol.2006.125583 |
0.429 |
|
2007 |
Li F, Dai XQ, Li Q, Wu Y, Chen XZ. Inhibition of polycystin-L channel by the Chinese herb Sparganum stoloniferum Buch.-Ham. Canadian Journal of Physiology and Pharmacology. 84: 923-7. PMID 17111037 DOI: 10.1139/y06-040 |
0.423 |
|
2006 |
Wu Y, Dai XQ, Li Q, Chen CX, Mai W, Hussain Z, Long W, Montalbetti N, Li G, Glynne R, Wang S, Cantiello HF, Wu G, Chen XZ. Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin. Human Molecular Genetics. 15: 3280-92. PMID 17008358 DOI: 10.1093/hmg/ddl404 |
0.317 |
|
2006 |
Li Q, Montalbetti N, Wu Y, Ramos A, Raychowdhury MK, Chen XZ, Cantiello HF. Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells. The Journal of Biological Chemistry. 281: 37566-75. PMID 16950792 DOI: 10.1074/jbc.M603643200 |
0.362 |
|
2006 |
Dai XQ, Karpinski E, Chen XZ. Permeation and inhibition of polycystin-L channel by monovalent organic cations. Biochimica Et Biophysica Acta. 1758: 197-205. PMID 16564495 DOI: 10.1016/j.bbamem.2006.01.020 |
0.426 |
|
2005 |
Montalbetti N, Li Q, González-Perrett S, Semprine J, Chen XZ, Cantiello HF. Effect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblast. PflüGers Archiv : European Journal of Physiology. 451: 294-303. PMID 16025301 DOI: 10.1007/s00424-005-1458-7 |
0.373 |
|
2005 |
Montalbetti N, Li Q, Timpanaro GA, González-Perrett S, Dai XQ, Chen XZ, Cantiello HF. Cytoskeletal regulation of calcium-permeable cation channels in the human syncytiotrophoblast: role of gelsolin. The Journal of Physiology. 566: 309-25. PMID 15845576 DOI: 10.1113/jphysiol.2005.087072 |
0.379 |
|
2004 |
Li Q, Dai XQ, Shen PY, Cantiello HF, Karpinski E, Chen XZ. A modified mammalian tandem affinity purification procedure to prepare functional polycystin-2 channel. Febs Letters. 576: 231-6. PMID 15474043 DOI: 10.1016/j.febslet.2004.09.017 |
0.315 |
|
2003 |
Li Q, Liu Y, Shen PY, Dai XQ, Wang S, Smillie LB, Sandford R, Chen XZ. Troponin I binds polycystin-L and inhibits its calcium-induced channel activation. Biochemistry. 42: 7618-25. PMID 12809519 DOI: 10.1021/Bi034210A |
0.425 |
|
2002 |
Liu Y, Li Q, Tan M, Zhang YY, Karpinski E, Zhou J, Chen XZ. Modulation of the human polycystin-L channel by voltage and divalent cations. Febs Letters. 525: 71-6. PMID 12163164 DOI: 10.1016/S0014-5793(02)03071-5 |
0.38 |
|
2002 |
Li Q, Liu Y, Zhao W, Chen XZ. The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation. Febs Letters. 516: 270-8. PMID 11959145 DOI: 10.1016/S0014-5793(02)02513-9 |
0.419 |
|
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