Scot A. Lieser, Ph.D.

Affiliations: 
2007 Chemistry University of California, San Diego, La Jolla, CA 
Area:
protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies
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"Scot Lieser"
Mean distance: 9.81
 
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Patricia A. Jennings grad student 2007 UCSD
 (Mechanistic characterization of Csk: The role of structural transitions and inter-domain crosstalk in enzyme function.)
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Publications

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Lieser SA, Shaffer J, Adams JA. (2006) SRC tail phosphorylation is limited by structural changes in the regulatory tyrosine kinase Csk. The Journal of Biological Chemistry. 281: 38004-12
Lieser SA, Aubol BE, Wong L, et al. (2005) Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochimica Et Biophysica Acta. 1754: 191-9
Wong L, Lieser SA, Miyashita O, et al. (2005) Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation. Journal of Molecular Biology. 351: 131-43
Lieser SA, Shindler C, Aubol BE, et al. (2005) Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition. The Journal of Biological Chemistry. 280: 7769-76
Wong L, Lieser S, Chie-Leon B, et al. (2004) Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. Journal of Molecular Biology. 341: 93-106
Lieser SA, Davis TC, Helmann JD, et al. (2003) DNA-binding and oligomerization studies of the manganese(II) metalloregulatory protein MntR from Bacillus subtilis. Biochemistry. 42: 12634-42
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