77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Mascarenhas R, Pietrzak M, Smith RM, Webb A, Wang D, Papp AC, Pinsonneault JK, Seweryn M, Rempala G, Sadee W. Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms. Plos One. 10: e0136798. PMID 26331722 DOI: 10.1371/Journal.Pone.0136798  0.536
2015 Lu R, Smith RM, Seweryn M, Wang D, Hartmann K, Webb A, Sadee W, Rempala GA. Analyzing allele specific RNA expression using mixture models. Bmc Genomics. 16: 566. PMID 26231172 DOI: 10.1186/S12864-015-1749-0  0.547
2015 Handelman SK, Seweryn M, Smith RM, Hartmann K, Wang D, Pietrzak M, Johnson AD, Kloczkowski A, Sadee W. Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs). Bmc Genomics. 16: S8. PMID 26111110 DOI: 10.1186/1471-2164-16-S8-S8  0.518
2014 Di Giorgio A, Smith RM, Fazio L, D'Ambrosio E, Gelao B, Tomasicchio A, Selvaggi P, Taurisano P, Quarto T, Masellis R, Rampino A, Caforio G, Popolizio T, Blasi G, Sadee W, et al. DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory. Plos One. 9: e95997. PMID 24819610 DOI: 10.1371/Journal.Pone.0095997  0.52
2014 Smith RM, Banks W, Hansen E, Sadee W, Herman GE. Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism Research : Official Journal of the International Society For Autism Research. 7: 459-67. PMID 24753316 DOI: 10.1002/Aur.1383  0.55
2013 Grevel J, Thomas J, Richards ML, Sadée W. Radioreceptor assay of narcotic analgesics in serum. Pharmaceutical Research. 1: 209-14. PMID 24277330 DOI: 10.1023/A:1016369229440  0.31
2013 Richards ML, Sadée W. Buprenorphine is an Antagonist at the ϰ Opioid Receptor. Pharmaceutical Research. 2: 178-81. PMID 24272810 DOI: 10.1023/A:1016340106299  0.339
2013 Smith RM, Webb A, Papp AC, Newman LC, Handelman SK, Suhy A, Mascarenhas R, Oberdick J, Sadee W. Whole transcriptome RNA-Seq allelic expression in human brain. Bmc Genomics. 14: 571. PMID 23968248 DOI: 10.1186/1471-2164-14-571  0.53
2013 Smith RM, Papp AC, Webb A, Ruble CL, Munsie LM, Nisenbaum LK, Kleinman JE, Lipska BK, Sadee W. Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex. Biological Psychiatry. 73: 546-54. PMID 23158458 DOI: 10.1016/J.Biopsych.2012.09.028  0.577
2012 Barrie ES, Smith RM, Sanford JC, Sadee W. mRNA transcript diversity creates new opportunities for pharmacological intervention. Molecular Pharmacology. 81: 620-30. PMID 22319206 DOI: 10.1124/Mol.111.076604  0.528
2011 Smith RM, Sadee W. Synaptic signaling and aberrant RNA splicing in autism spectrum disorders. Frontiers in Synaptic Neuroscience. 3: 1. PMID 21423409 DOI: 10.3389/Fnsyn.2011.00001  0.511
2011 Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, Johnson AD. Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy. Clinical Pharmacology and Therapeutics. 89: 355-65. PMID 21289622 DOI: 10.1038/Clpt.2010.314  0.534
2011 Moyer RA, Wang D, Papp AC, Smith RM, Duque L, Mash DC, Sadee W. Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 753-62. PMID 21150907 DOI: 10.1038/Npp.2010.208  0.528
2011 Smith RM, Alachkar H, Papp AC, Wang D, Mash DC, Wang JC, Bierut LJ, Sadee W. Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms. European Journal of Human Genetics : Ejhg. 19: 76-83. PMID 20700147 DOI: 10.1038/Ejhg.2010.120  0.549
2009 Roe BE, Tilley MR, Gu HH, Beversdorf DQ, Sadee W, Haab TC, Papp AC. Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. Plos One. 4: e6704. PMID 19693267 DOI: 10.1371/Journal.Pone.0006704  0.516
2008 Johnson AD, Zhang Y, Papp AC, Pinsonneault JK, Lim JE, Saffen D, Dai Z, Wang D, Sadée W. Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues. Pharmacogenetics and Genomics. 18: 781-91. PMID 18698231 DOI: 10.1097/Fpc.0B013E3283050107  0.506
2007 Lim JE, Pinsonneault J, Sadee W, Saffen D. Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons. Molecular Psychiatry. 12: 491-501. PMID 17453063 DOI: 10.1038/sj.mp.4001923  0.496
2006 Lim JE, Papp A, Pinsonneault J, Sadée W, Saffen D. Allelic expression of serotonin transporter (SERT) mRNA in human pons: lack of correlation with the polymorphism SERTLPR. Molecular Psychiatry. 11: 649-62. PMID 16432527 DOI: 10.1038/sj.mp.4001797  0.485
2003 Han G, Quillan JM, Carlson K, Sadée W, Hruby VJ. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist. Journal of Medicinal Chemistry. 46: 810-9. PMID 12593660 DOI: 10.1021/Jm020355O  0.348
2002 Botka CW, Wittig TW, Graul RC, Nielsen CU, Higaka K, Amidon GL, Sadée W. Human proton/oligopeptide transporter (POT) genes: identification of putative human genes using bioinformatics. Aaps Pharmsci. 2: E16. PMID 11741232 DOI: 10.1208/Ps020216  0.301
2001 Lucas JL, DeYoung JA, Sadee W. Single nucleotide polymorphisms of the human M1 muscarinic acetylcholine receptor gene Aaps Pharmsci [Electronic Resource]. 3: E31. PMID 12049494 DOI: 10.1208/Ps030431  0.352
2001 Sadee W, Hoeg E, Lucas J, Wang D. Genetic variations in human G protein-coupled receptors: implications for drug therapy. Aaps Pharmsci. 3: E22. PMID 11741273 DOI: 10.1208/Ps030322  0.378
2001 Wang D, Quillan JM, Winans K, Lucas JL, Sadée W. Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding. The Journal of Biological Chemistry. 276: 34624-30. PMID 11457836 DOI: 10.1074/Jbc.M104083200  0.375
2001 Wang D, Raehal KM, Bilsky EJ, Sadée W. Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence. Journal of Neurochemistry. 77: 1590-600. PMID 11413242 DOI: 10.1046/J.1471-4159.2001.00362.X  0.334
2001 Graul RC, Sadee W. Evolutionary relationships among G protein-coupled receptors using a clustered database approach Aaps Pharmsci. 3. DOI: 10.1208/Ps030212  0.32
2000 Wang D, Tolbert LM, Carlson KW, Sadée W. Nuclear Ca2+/calmodulin translocation activated by mu-opioid (OP3) receptor. Journal of Neurochemistry. 74: 1418-25. PMID 10737597 DOI: 10.1046/J.1471-4159.2000.0741418.X  0.342
2000 Wang Z, Sadée W. Tolerance to morphine at the mu-opioid receptor differentially induced by cAMP-dependent protein kinase activation and morphine. European Journal of Pharmacology. 389: 165-71. PMID 10688980 DOI: 10.1016/S0014-2999(99)00881-X  0.338
2000 Choi DS, Wang D, Tolbert L, Sadée W. Basal signaling activity of human dopamine D2L receptor demonstrated with an ecdysone-inducible mammalian expression system Journal of Neuroscience Methods. 94: 217-225. PMID 10661841 DOI: 10.1016/S0165-0270(99)00147-8  0.348
1999 Shockley MS, Tolbert LM, Tobin AB, Nahorski SR, Sadée W, Lameh J. Differential regulation of muscarinic M1 and M3 receptors by a putative phosphorylation domain. European Journal of Pharmacology. 377: 137-46. PMID 10448936 DOI: 10.1016/S0014-2999(99)00303-9  0.314
1999 Wang D, Sadée W, Quillan JM. Calmodulin binding to G protein-coupling domain of opioid receptors. The Journal of Biological Chemistry. 274: 22081-8. PMID 10419536 DOI: 10.1074/Jbc.274.31.22081  0.377
1999 Ito K, Haga T, Lameh J, Sadée W. Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5. European Journal of Biochemistry. 260: 112-9. PMID 10091590 DOI: 10.1046/J.1432-1327.1999.00125.X  0.344
1998 Quillan JM, Sadée W, Wei ET, Jimenez C, Ji L, Chang JK. A synthetic human Agouti-related protein-(83-132)-NH2 fragment is a potent inhibitor of melanocortin receptor function. Febs Letters. 428: 59-62. PMID 9645475 DOI: 10.1016/S0014-5793(98)00487-6  0.313
1998 Burford NT, Tolbert LM, Sadee W. Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I. European Journal of Pharmacology. 342: 123-6. PMID 9544801 DOI: 10.1016/S0014-2999(97)01556-2  0.328
1998 Tsuga H, Kameyama K, Haga T, Honma T, Lameh J, Sadée W. Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 273: 5323-30. PMID 9478991 DOI: 10.1074/Jbc.273.9.5323  0.367
1998 Lu YF, Xu H, Liu-Chen LY, Chen C, Partilla JS, Brine GA, Carroll FI, Rice KC, Lai J, Porreca F, Sadee W, Rothman RB. Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor. Synapse (New York, N.Y.). 28: 117-24. PMID 9450512 DOI: 10.1002/(Sici)1098-2396(199802)28:2<117::Aid-Syn2>3.0.Co;2-E  0.369
1997 Shockley MS, Burford NT, Sadée W, Lameh J. Residues specifically involved in down-regulation but not internalization of the m1 muscarinic acetylcholine receptor. Journal of Neurochemistry. 68: 601-9. PMID 9003046 DOI: 10.1046/J.1471-4159.1997.68020601.X  0.348
1996 Bilsky EJ, Inturrisi CE, Sadée W, Hruby VJ, Porreca F. Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective μ or δ opioid agonists in mice Pain. 68: 229-237. PMID 9121809 DOI: 10.1016/S0304-3959(96)03185-5  0.31
1996 Wang Z, Arden J, Sadée W. Basal phosphorylation of mu opioid receptor is agonist modulated and Ca2+-dependent. Febs Letters. 387: 53-7. PMID 8654566 DOI: 10.1016/0014-5793(96)00467-X  0.335
1995 Kameyama K, Haga K, Haga T, Moro O, Sadée W. Activation of a GTP-binding protein and a GTP-binding-protein-coupled receptor kinase (beta-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites. European Journal of Biochemistry. 226: 267-76. PMID 8001544 DOI: 10.1111/J.1432-1033.1994.Tb20050.X  0.341
1995 Sadée W, Wang Z. Agonist induced constitutive receptor activation as a novel regulatory mechanism. Mu receptor regulation. Advances in Experimental Medicine and Biology. 373: 85-90. PMID 7668164 DOI: 10.1007/978-1-4615-1951-5_12  0.369
1995 Shockley M, Högger P, Lameh J, Sadée W. Identification of residues in the intracellular loops of the human muscarinic cholinergic HM1 receptor involved in G-protein coupling and down-regulation Life Sciences. 56: 1030. DOI: 10.1016/0024-3205(95)93772-7  0.32
1994 Wang Z, Bilsky EJ, Porreca F, Sadee W. Constitutive μ opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence Life Sciences. 54. PMID 7514710 DOI: 10.1016/0024-3205(94)90022-1  0.33
1994 Wang Z, Arden JR, Segredo V, Sadée W. Agonist induced constitutive activation of the μ opioid receptor by phosphorylation Regulatory Peptides. 54: 323-324. DOI: 10.1016/0167-0115(94)90519-3  0.36
1994 Wang Z, Sadée W. Constitutive μ opioid receptor activity in human neuroblastoma SK-N-SH cells Regulatory Peptides. 53: S283-S284. DOI: 10.1016/0167-0115(94)90348-4  0.357
1993 Drübbisch V, Lameh J, Philip M, Sharma YK, Sadée W. Mapping the ligand binding pocket of the human muscarinic cholinergic receptor Hm1: contribution of tyrosine-82. Pharmaceutical Research. 9: 1644-7. PMID 1488411 DOI: 10.1023/A:1015885029612  0.33
1992 Cook JS, Wolsing DH, Lameh J, Olson CA, Correa PE, Sadee W, Blumenthal EM, Rosenbaum JS. Characterization of the RDC1 gene which encodes the canine homolog of a proposed human VIP receptor. Expression does not correlate with an increase in VIP binding sites. Febs Letters. 300: 149-52. PMID 1373390 DOI: 10.1016/0014-5793(92)80184-I  0.352
1992 Lameh J, Eiger S, Sadée W. Interaction among mu-opioid receptors and alpha 2-adrenoceptors on SH-SY5Y human neuroblastoma cells. European Journal of Pharmacology. 227: 19-24. PMID 1358661 DOI: 10.1016/0922-4106(92)90137-K  0.308
1992 Cone RI, Rosenfeld S, Lameh J, Sadée W. 125I-beta-endorphin binding to neuroblastoma X glioma NG108-15 cells: distribution of delta opioid receptors. Life Sciences. 51: PL219-24. PMID 1331640 DOI: 10.1016/0024-3205(92)90306-A  0.312
1991 Cone RI, Lameh J, Sadée W. Rapid agonist-induced loss of 125I-beta-endorphin opioid receptor sites in NG108-15, but not SK-N-SH neuroblastoma cells. Life Sciences. 49: PL147-52. PMID 1658508 DOI: 10.1016/0024-3205(91)90396-S  0.347
1991 Maeda S, Lameh J, Philip M, Sadee W. Functions of the third cytoplasmic loop of human m1 muscarinic cholinergic receptors : Receptor internalization and phosphatidyl inositol turnover Neuroscience Research Supplements. 14: S136. DOI: 10.1016/S0921-8696(06)80397-X  0.33
1990 Maeda S, Lameh J, Mallet WG, Philip M, Ramachandran J, Sadée W. Internalization of the Hm1 muscarinic cholinergic receptor involves the third cytoplasmic loop. Febs Letters. 269: 386-8. PMID 2401364 DOI: 10.1016/0014-5793(90)81199-X  0.344
1990 Lameh J, Cone RI, Maeda S, Philip M, Corbani M, Nádasdi L, Ramachandran J, Smith GM, Sadée W. Structure and function of G protein coupled receptors. Pharmaceutical Research. 7: 1213-21. PMID 1965663 DOI: 10.1023/A:1015969301407  0.319
1990 Yu VC, Eiger S, Duan DS, Lameh J, Sadée W. Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells. Journal of Neurochemistry. 55: 1390-6. PMID 1697894 DOI: 10.1111/J.1471-4159.1990.Tb03151.X  0.346
1988 Hochhaus G, Sadée W. A Biotin–Avidin-Based Enzyme Immunoassay for βh-Endorphin Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 5: 232-235. PMID 2977649 DOI: 10.1023/A:1015993713471  0.504
1988 Hochhaus G, Patthy A, Schwietert R, Santi DV, Sadée W. [Biocytin13]Dynorphin A 1-13 Amide: A Potential Probe for the κ-Opioid Receptor Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 5: 790-794. PMID 2907785 DOI: 10.1023/A:1015944903360  0.573
1988 Sadee W, Yu VC, Hochhaus G. Effects of opioid peptides on human neuroblastoma cells Nida Research Monograph Series. 111-117. PMID 2855093  0.469
1988 Preis PN, Saya H, Nadasdi L, Hochhaus G, Levin V, Sadee W. Neuronal Cell Differentiation of Human Neuroblastoma Cells by Retinoic Acid plus Herbimycin A Cancer Research. 48: 6530-6534. PMID 2846152  0.451
1988 Hochhaus G, Gibson BW, Sadee W. Biotinylated human β-endorphins as probes for the opioid receptor Journal of Biological Chemistry. 263: 92-97. PMID 2826453  0.517
1987 Yu VC, Sadée W. Phosphatidylinositol turnover in neuroblastoma cells: regulation by bradykinin, acetylcholine, but not mu- and delta-opioid receptors. Neuroscience Letters. 71: 219-23. PMID 3024076 DOI: 10.1016/0304-3940(86)90562-8  0.364
1986 Lybrand TP, Kollman PA, Yu VC, Sadée W. Conformation and electrostatic potential surfaces of opiates: Relationship to µ- and λ-site binding. Pharmaceutical Research. 3: 218-24. PMID 24271585 DOI: 10.1023/A:1016338730077  0.324
1986 Richards ML, Sadeé W. In vivo binding of putative delta-selective opioid antagonists to central opiate receptors. European Journal of Pharmacology. 126: 313-6. PMID 3019718 DOI: 10.1016/0014-2999(86)90064-6  0.37
1986 Hochhaus G, Yu VC, Sadée W. Delta opioid receptor in human neuroblastoma cell lines Brain Research. 382: 327-331. PMID 3019481 DOI: 10.1016/0006-8993(86)91341-7  0.557
1986 Hochhaus G, Gibson BW, Sadée W. Development of a biotin-avidin probe for detecting opioid receptors Nida Research Monograph. 75: 33-36. PMID 2828982  0.488
1985 Richards ML, Sadée W. In vivo opiate receptor binding of oripavines to mu, delta and kappa sites in rat brain as determined by an ex vivo labeling method. European Journal of Pharmacology. 114: 343-53. PMID 2998812 DOI: 10.1016/0014-2999(85)90379-6  0.364
1985 Grevel J, Yu V, Sadée W. Characterization of a labile naloxone binding site (lambda site) in rat brain. Journal of Neurochemistry. 44: 1647-56. PMID 2985759 DOI: 10.1111/J.1471-4159.1985.Tb08808.X  0.306
1984 Rosenbaum JS, Holford NH, Sadée W. Opiate receptor binding-effect relationship: sufentanil and etorphine produce analgesia at the mu-site with low fractional receptor occupancy. Brain Research. 291: 317-24. PMID 6320962 DOI: 10.1016/0006-8993(84)91264-2  0.315
1984 Sadée W, Richards ML, Grevel J, Rosenbaum JS. In vivo characterization of four types of opioid binding sites in rat brain. Life Sciences. 187-9. PMID 6141486 DOI: 10.1016/0024-3205(83)90474-5  0.347
1983 Rosenbaum JS, Kurowski M, Aman RA, Sadée W. Partial loss of opiate receptor regulation by GPP(NH)P evident in vitro. Life Sciences. 31: 1667-70. PMID 6296568 DOI: 10.1016/0024-3205(82)90181-3  0.353
1983 Perry DC, Rosenbaum JS, Sadee W. In vivo binding of 3H-etorphine in morphine-dependent rats. Life Sciences. 31: 1405-8. PMID 6292637 DOI: 10.1016/0024-3205(82)90392-7  0.355
1983 Rosenbaum JS, Sadée W. Demonstration of opiate receptor sub-types in vivo. Life Sciences. 31: 1299-301. PMID 6292617 DOI: 10.1016/0024-3205(82)90366-6  0.318
1983 Kurowski M, Rosenbaum JS, Perry DC, Sadée W. [3H]-etorphine and [3H]-diprenorphine receptor binding in vitro and in vivo: differential effect of Na+ and guanylyl imidodiphosphate. Brain Research. 249: 345-52. PMID 6291717 DOI: 10.1016/0006-8993(82)90068-3  0.346
1982 Sadée W, Perry DC, Rosenbaum JS, Herz A. [3H]diprenorphine receptor binding in vivo and in vitro. European Journal of Pharmacology. 81: 431-40. PMID 6288412 DOI: 10.1016/0014-2999(82)90108-X  0.32
1980 Perry DC, Mullis KB, Oie S, Sadée W. Opiate antagonist receptor binding in vivo: evidence for a new receptor binding model. Brain Research. 199: 49-61. PMID 6250676 DOI: 10.1016/0006-8993(80)90229-2  0.365
1973 CASTAGNOLI N, SADEE W. ChemInform Abstract: MECHANISMEN DER RK. EINES 1,4-BENZODIAZEPIN-N-OXIDES MIT ACETANHYDRID Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197306283  0.409
1972 Castagnoli N, Sadée W. Mechanism of the reaction of a 1,4-benzodiazepine N-oxide with acetic anhydride. Journal of Medicinal Chemistry. 15: 1076-8. PMID 5069778 DOI: 10.1021/Jm00280A024  0.405
1971 Sadèe W, Garland W, Castagnoli N. Microsomal 3-hydroxylation of 1,4-benzodiazepines. Journal of Medicinal Chemistry. 14: 643-5. PMID 5164455  0.435
1971 SADEE W, GARLAND W, CASTAGNOLI N. ChemInform Abstract: MIKROSOMALE 3-HYDROXYLIERUNG VON 1,4-BENZODIAZEPINEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197143360  0.388
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