Julian F. Hillyer, Ph.D. - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Parasitology/Medical Entomology, Mosquito-Parasite Relationships, Innate Immunity in Mosquitoes

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yan Y, Sigle LT, Rinker DC, Estévez-Lao TY, Capra JA, Hillyer JF. The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes. Open Biology. 12: 220111. PMID 36069078 DOI: 10.1098/rsob.220111  0.369
2022 Yan Y, Ramakrishnan A, Estévez-Lao TY, Hillyer JF. Transglutaminase 3 negatively regulates immune responses on the heart of the mosquito, Anopheles gambiae. Scientific Reports. 12: 6715. PMID 35468918 DOI: 10.1038/s41598-022-10766-z  0.41
2020 Yan Y, Hillyer JF. The immune and circulatory systems are functionally integrated across insect evolution. Science Advances. 6. PMID 33239286 DOI: 10.1126/sciadv.abb3164  0.334
2020 Estévez-Lao TY, Sigle LT, Gomez SN, Hillyer JF. Nitric oxide produced by periostial hemocytes modulates the bacterial infection induced reduction of the mosquito heart rate. The Journal of Experimental Biology. PMID 32561636 DOI: 10.1242/Jeb.225821  0.401
2020 Powers JC, Turangan R, Joosse BA, Hillyer JF. Adult Mosquitoes Infected with Bacteria Early in Life Have Stronger Antimicrobial Responses and More Hemocytes after Reinfection Later in Life. Insects. 11. PMID 32481519 DOI: 10.3390/Insects11060331  0.41
2020 Adema CM, Hillyer JF. Immunity in invertebrate disease vectors: editorial introduction to the special issue. Developmental and Comparative Immunology. 103684. PMID 32194143 DOI: 10.1016/J.Dci.2020.103684  0.381
2019 Hillyer JF, Pass G. The Insect Circulatory System: Structure, Function, and Evolution. Annual Review of Entomology. PMID 31585504 DOI: 10.1146/Annurev-Ento-011019-025003  0.339
2019 Brown LD, Shapiro LLM, Thompson GA, Estévez-Lao TY, Hillyer JF. Transstadial immune activation in a mosquito: Adults that emerge from infected larvae have stronger antibacterial activity in their hemocoel yet increased susceptibility to malaria infection. Ecology and Evolution. 9: 6082-6095. PMID 31161020 DOI: 10.1002/Ece3.5192  0.459
2019 Yan Y, Hillyer JF. Complement-like proteins TEP1, TEP3 and TEP4 are positive regulators of periostial hemocyte aggregation in the mosquito Anopheles gambiae. Insect Biochemistry and Molecular Biology. PMID 30690067 DOI: 10.1016/J.Ibmb.2019.01.007  0.481
2018 Hillyer JF. Insect heart rhythmicity is modulated by evolutionarily conserved neuropeptides and neurotransmitters. Current Opinion in Insect Science. 29: 41-48. PMID 30551824 DOI: 10.1016/J.Cois.2018.06.002  0.335
2018 Sigle LT, Hillyer JF. Mosquito Hemocytes Associate With Circulatory Structures That Support Intracardiac Retrograde Hemolymph Flow. Frontiers in Physiology. 9: 1187. PMID 30210361 DOI: 10.3389/Fphys.2018.01187  0.423
2018 Sigle LT, Hillyer JF. Structural and functional characterization of the contractile aorta and associated hemocytes of the mosquito . The Journal of Experimental Biology. PMID 29724775 DOI: 10.1242/Jeb.181107  0.31
2018 Sigle LT, Hillyer JF. Eater and draper are involved in the periostial haemocyte immune response in the mosquito Anopheles gambiae. Insect Molecular Biology. 27: 429-438. PMID 29520896 DOI: 10.1111/Imb.12383  0.495
2017 Brown LD, Thompson GA, Hillyer JF. Transstadial transmission of larval hemocoelic infection negatively affects development and adult female longevity in the mosquito Anopheles gambiae. Journal of Invertebrate Pathology. PMID 29111355 DOI: 10.1016/J.Jip.2017.10.008  0.392
2017 League GP, Estévez-Lao TY, Yan Y, Garcia-Lopez VA, Hillyer JF. Anopheles gambiae larvae mount stronger immune responses against bacterial infection than adults: evidence of adaptive decoupling in mosquitoes. Parasites & Vectors. 10: 367. PMID 28764812 DOI: 10.1186/S13071-017-2302-6  0.456
2017 Doran CR, Estévez-Lao TY, Hillyer JF. Mosquito aging modulates the heart rate and the proportional directionality of heart contractions. Journal of Insect Physiology. PMID 28655496 DOI: 10.1016/J.Jinsphys.2017.06.013  0.3
2016 League GP, Hillyer JF. Functional integration of the circulatory, immune, and respiratory systems in mosquito larvae: pathogen killing in the hemocyte-rich tracheal tufts. Bmc Biology. 14: 78. PMID 27643786 DOI: 10.1186/S12915-016-0305-Y  0.442
2016 Suggs JM, Jones TH, Murphree CS, Hillyer JF. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. The Journal of Experimental Biology. PMID 27247317 DOI: 10.1242/Jeb.141655  0.302
2015 Hillyer JF. Insect immunology and hematopoiesis. Developmental and Comparative Immunology. PMID 26695127 DOI: 10.1016/J.Dci.2015.12.006  0.476
2015 Sigle LT, Hillyer JF. Mosquito hemocytes preferentially aggregate and phagocytose pathogens in the periostial regions of the heart that experience the most hemolymph flow. Developmental and Comparative Immunology. 55: 90-101. PMID 26526332 DOI: 10.1016/J.Dci.2015.10.018  0.448
2015 Hillyer JF. Integrated Immune and Cardiovascular Function in Pancrustacea: Lessons from the Insects. Integrative and Comparative Biology. PMID 25898841 DOI: 10.1093/Icb/Icv021  0.491
2015 Ellison HE, Estévez-Lao TY, Murphree CS, Hillyer JF. Deprivation of both sucrose and water reduces the mosquito heart contraction rate while increasing the expression of nitric oxide synthase. Journal of Insect Physiology. 74: 1-9. PMID 25640058 DOI: 10.1016/J.Jinsphys.2015.01.011  0.303
2015 League GP, Onuh OC, Hillyer JF. Comparative structural and functional analysis of the larval and adult dorsal vessel and its role in hemolymph circulation in the mosquito Anopheles gambiae. The Journal of Experimental Biology. 218: 370-80. PMID 25524976 DOI: 10.1242/Jeb.114942  0.321
2015 Kong L, Lu A, Guan J, Yang B, Li M, Hillyer JF, Ramarao N, Söderhäll K, Liu C, Ling E. Thermolysin damages animal life through degradation of plasma proteins enhanced by rapid cleavage of serpins and activation of proteases. Archives of Insect Biochemistry and Physiology. 88: 64-84. PMID 25042057 DOI: 10.1002/Arch.21178  0.322
2014 Hillyer JF. Editorial overview: Vectors and medical and veterinary entomology: Immune responses to pathogen infections in insect vectors. Current Opinion in Insect Science. 3: v-vii. PMID 32846698 DOI: 10.1016/J.Cois.2014.08.010  0.446
2014 Hillyer JF, Strand MR. Mosquito hemocyte-mediated immune responses. Current Opinion in Insect Science. 3: 14-21. PMID 25309850 DOI: 10.1016/J.Cois.2014.07.002  0.496
2014 Hillyer JF, Estévez-Lao TY, de la Parte LE. Myotropic effects of FMRFamide containing peptides on the heart of the mosquito Anopheles gambiae. General and Comparative Endocrinology. 202: 15-25. PMID 24747482 DOI: 10.1016/J.Ygcen.2014.03.048  0.329
2014 Estévez-Lao TY, Hillyer JF. Involvement of the Anopheles gambiae Nimrod gene family in mosquito immune responses. Insect Biochemistry and Molecular Biology. 44: 12-22. PMID 24200842 DOI: 10.1016/J.Ibmb.2013.10.008  0.381
2014 Hillyer JF. Editorial overview: Vectors and medical and veterinary entomology: Immune responses to pathogen infections in insect vectors Current Opinion in Insect Science. 3: v-vii. DOI: 10.1016/j.cois.2014.08.010  0.345
2013 Chen W, Hillyer JF. FlyNap (triethylamine) increases the heart rate of mosquitoes and eliminates the cardioacceleratory effect of the neuropeptide CCAP. Plos One. 8: e70414. PMID 23875027 DOI: 10.1371/Journal.Pone.0070414  0.364
2013 King JG, Hillyer JF. Spatial and temporal in vivo analysis of circulating and sessile immune cells in mosquitoes: hemocyte mitosis following infection. Bmc Biology. 11: 55. PMID 23631603 DOI: 10.1186/1741-7007-11-55  0.485
2013 Xu J, Hillyer JF, Coulibaly B, Sacko M, Dao A, Niaré O, Riehle MM, Traoré SF, Vernick KD. Wild Anopheles funestus mosquito genotypes are permissive for infection with the rodent malaria parasite, Plasmodium berghei. Plos One. 8: e61181. PMID 23593423 DOI: 10.1371/Journal.Pone.0061181  0.341
2013 Estévez-Lao TY, Boyce DS, Honegger HW, Hillyer JF. Cardioacceleratory function of the neurohormone CCAP in the mosquito Anopheles gambiae. The Journal of Experimental Biology. 216: 601-13. PMID 23364571 DOI: 10.1242/Jeb.077164  0.364
2012 King JG, Hillyer JF. Infection-induced interaction between the mosquito circulatory and immune systems. Plos Pathogens. 8: e1003058. PMID 23209421 DOI: 10.1371/Journal.Ppat.1003058  0.518
2012 Murdock CC, Paaijmans KP, Bell AS, King JG, Hillyer JF, Read AF, Thomas MB. Complex effects of temperature on mosquito immune function. Proceedings. Biological Sciences / the Royal Society. 279: 3357-66. PMID 22593107 DOI: 10.1098/Rspb.2012.0638  0.439
2012 Hillyer JF, Estévez-Lao TY, Funkhouser LJ, Aluoch VA. Anopheles gambiae corazonin: gene structure, expression and effect on mosquito heart physiology. Insect Molecular Biology. 21: 343-55. PMID 22404523 DOI: 10.1111/J.1365-2583.2012.01140.X  0.358
2012 Coggins SA, Estévez-Lao TY, Hillyer JF. Increased survivorship following bacterial infection by the mosquito Aedes aegypti as compared to Anopheles gambiae correlates with increased transcriptional induction of antimicrobial peptides. Developmental and Comparative Immunology. 37: 390-401. PMID 22326457 DOI: 10.1016/J.Dci.2012.01.005  0.502
2011 King JG, Vernick KD, Hillyer JF. Members of the salivary gland surface protein (SGS) family are major immunogenic components of mosquito saliva. The Journal of Biological Chemistry. 286: 40824-34. PMID 21965675 DOI: 10.1074/Jbc.M111.280552  0.424
2010 Hillyer JF. Mosquito immunity. Advances in Experimental Medicine and Biology. 708: 218-38. PMID 21528701 DOI: 10.1007/978-1-4419-8059-5-12  0.405
2010 Aliota MT, Fuchs JF, Rocheleau TA, Clark AK, Hillyer JF, Chen CC, Christensen BM. Mosquito transcriptome profiles and filarial worm susceptibility in Armigeres subalbatus. Plos Neglected Tropical Diseases. 4: e666. PMID 20421927 DOI: 10.1371/Journal.Pntd.0000666  0.687
2010 Glenn JD, King JG, Hillyer JF. Structural mechanics of the mosquito heart and its function in bidirectional hemolymph transport. The Journal of Experimental Biology. 213: 541-50. PMID 20118304 DOI: 10.1242/Jeb.035014  0.321
2010 Hillyer JF, Estévez-Lao TY. Nitric oxide is an essential component of the hemocyte-mediated mosquito immune response against bacteria. Developmental and Comparative Immunology. 34: 141-9. PMID 19733588 DOI: 10.1016/J.Dci.2009.08.014  0.334
2009 Hillyer JF. Transcription in mosquito hemocytes in response to pathogen exposure. Journal of Biology. 8: 51. PMID 19519953 DOI: 10.1186/Jbiol151  0.477
2007 Hillyer JF, Barreau C, Vernick KD. Efficiency of salivary gland invasion by malaria sporozoites is controlled by rapid sporozoite destruction in the mosquito haemocoel. International Journal For Parasitology. 37: 673-81. PMID 17275826 DOI: 10.1016/J.Ijpara.2006.12.007  0.387
2005 Hillyer JF, Christensen BM. Mosquito phenoloxidase and defensin colocalize in melanization innate immune responses. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 689-98. PMID 15928318 DOI: 10.1369/Jhc.4A6564.2005  0.631
2005 Hillyer JF, Schmidt SL, Fuchs JF, Boyle JP, Christensen BM. Age-associated mortality in immune challenged mosquitoes (Aedes aegypti) correlates with a decrease in haemocyte numbers. Cellular Microbiology. 7: 39-51. PMID 15617522 DOI: 10.1111/J.1462-5822.2004.00430.X  0.569
2005 Wang X, Fuchs JF, Infanger LC, Rocheleau TA, Hillyer JF, Chen CC, Christensen BM. Mosquito innate immunity: involvement of beta 1,3-glucan recognition protein in melanotic encapsulation immune responses in Armigeres subalbatus. Molecular and Biochemical Parasitology. 139: 65-73. PMID 15610820 DOI: 10.1016/J.Molbiopara.2004.09.009  0.579
2004 Wang X, Rocheleau TA, Fuchs JF, Hillyer JF, Chen CC, Christensen BM. A novel lectin with a fibrinogen-like domain and its potential involvement in the innate immune response of Armigeres subalbatus against bacteria. Insect Molecular Biology. 13: 273-82. PMID 15157228 DOI: 10.1111/J.0962-1075.2004.00484.X  0.587
2004 Hillyer JF, Schmidt SL, Christensen BM. The antibacterial innate immune response by the mosquito Aedes aegypti is mediated by hemocytes and independent of Gram type and pathogenicity. Microbes and Infection / Institut Pasteur. 6: 448-59. PMID 15109959 DOI: 10.1016/J.Micinf.2004.01.005  0.627
2003 Boyle JP, Hillyer JF, Yoshino TP. Pharmacological and autoradiographical characterization of serotonin transporter-like activity in sporocysts of the human blood fluke, Schistosoma mansoni. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 189: 631-41. PMID 12861423 DOI: 10.1007/S00359-003-0429-8  0.318
2003 Hillyer JF, Schmidt SL, Christensen BM. Hemocyte-mediated phagocytosis and melanization in the mosquito Armigeres subalbatus following immune challenge by bacteria. Cell and Tissue Research. 313: 117-27. PMID 12838409 DOI: 10.1007/S00441-003-0744-Y  0.642
2003 Hillyer JF, Schmidt SL, Christensen BM. Rapid phagocytosis and melanization of bacteria and Plasmodium sporozoites by hemocytes of the mosquito Aedes aegypti. The Journal of Parasitology. 89: 62-9. PMID 12659304 DOI: 10.1645/0022-3395(2003)089[0062:Rpamob]2.0.Co;2  0.631
2003 Johnson JK, Rocheleau TA, Hillyer JF, Chen CC, Li J, Christensen BM. A potential role for phenylalanine hydroxylase in mosquito immune responses. Insect Biochemistry and Molecular Biology. 33: 345-54. PMID 12609519 DOI: 10.1016/S0965-1748(02)00257-6  0.65
2002 Hillyer JF, Christensen BM. Characterization of hemocytes from the yellow fever mosquito, Aedes aegypti. Histochemistry and Cell Biology. 117: 431-40. PMID 12029490 DOI: 10.1007/S00418-002-0408-0  0.628
2001 Smartt CT, Kiley LM, Hillyer JF, Dasgupta R, Christensen BM. Aedes aegypti glutamine synthetase: expression and gene structure. Gene. 274: 35-45. PMID 11674996 DOI: 10.1016/S0378-1119(01)00618-7  0.549
2000 Zhao X, Smartt CT, Hillyer JF, Christensen BM. A novel member of the RING-finger gene family associated with reproductive tissues of the mosquito, Aaedes aegypti. Insect Molecular Biology. 9: 301-8. PMID 10886414 DOI: 10.1046/J.1365-2583.2000.00189.X  0.538
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