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Emily K. Osterweil, Ph.D. - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
cytoskeleton. Epithelial cell biology. molecular motors
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Louros SR, Seo SS, Maio B, Martinez-Gonzalez C, Gonzalez-Lozano MA, Muscas M, Verity NC, Wills JC, Li KW, Nolan MF, Osterweil EK. Excessive proteostasis contributes to pathology in fragile X syndrome. Neuron. PMID 36495869 DOI: 10.1016/j.neuron.2022.11.012  0.319
2022 Seo SS, Louros SR, Anstey N, Gonzalez-Lozano MA, Harper CB, Verity NC, Dando O, Thomson SR, Darnell JC, Kind PC, Li KW, Osterweil EK. Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome. Nature Communications. 13: 3236. PMID 35688821 DOI: 10.1038/s41467-022-30979-0  0.342
2020 Osterweil EK. Seizing control of fragile X Syndrome Science Translational Medicine. 12. DOI: 10.1126/Scitranslmed.Aba2902  0.34
2019 Muscas M, Louros SR, Osterweil EK. Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model. Eneuro. 6. PMID 31147392 DOI: 10.1523/ENEURO.0097-19.2019  0.305
2019 Asiminas A, Jackson AD, Louros SR, Till SM, Spano T, Dando O, Bear MF, Chattarji S, Hardingham GE, Osterweil EK, Wyllie DJA, Wood ER, Kind PC. Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome. Science Translational Medicine. 11. PMID 31142675 DOI: 10.1126/Scitranslmed.Aao0498  0.336
2019 Osterweil EK. A no-nonsense treatment for autism spectrum disorder Science Translational Medicine. 11: eaaz3723. DOI: 10.1126/Scitranslmed.Aaz3723  0.326
2019 Osterweil EK. Of mice, men, and NLGN4 Science Translational Medicine. 11: eaaz0307. DOI: 10.1126/Scitranslmed.Aaz0307  0.311
2019 Osterweil EK. A primate resource for autism research Science Translational Medicine. 11. DOI: 10.1126/Scitranslmed.Aay3571  0.303
2019 Osterweil EK. Upsetting the excitatory-inhibitory balance hypothesis of autism Science Translational Medicine. 11: eaax2730. DOI: 10.1126/Scitranslmed.Aax2730  0.376
2017 Thomson SR, Seo SS, Barnes SA, Louros SR, Muscas M, Dando O, Kirby C, Wyllie DJA, Hardingham GE, Kind PC, Osterweil EK. Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome. Neuron. 95: 550-563.e5. PMID 28772121 DOI: 10.1016/J.Neuron.2017.07.013  0.416
2016 Tao J, Wu H, Coronado AA, de Laittre E, Osterweil EK, Zhang Y, Bear MF. Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11946-11958. PMID 27881780 DOI: 10.1523/Jneurosci.0672-16.2016  0.469
2016 Louros SR, Osterweil EK. Perturbed proteostasis in autism spectrum disorders. Journal of Neurochemistry. PMID 27365114 DOI: 10.1111/Jnc.13723  0.417
2015 Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SG, Bear MF, Nägerl UV, Kind PC, Wyllie DJ. Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15073-81. PMID 26558778 DOI: 10.1523/Jneurosci.1087-15.2015  0.485
2015 Sidorov MS, Kaplan ES, Osterweil EK, Lindemann L, Bear MF. Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417096 DOI: 10.1073/Pnas.1512878112  0.379
2015 Till SM, Asiminas A, Jackson AD, Katsanevaki D, Barnes SA, Osterweil EK, Bear MF, Chattarji S, Wood ER, Wyllie DJ, Kind PC. Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS. Human Molecular Genetics. PMID 26243794 DOI: 10.1093/Hmg/Ddv299  0.394
2014 Sidorov MS, Krueger DD, Taylor M, Gisin E, Osterweil EK, Bear MF. Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice. Genes, Brain, and Behavior. PMID 24684608 DOI: 10.1111/Gbb.12137  0.416
2013 Lohith TG, Osterweil EK, Fujita M, Jenko KJ, Bear MF, Innis RB. Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome? Molecular Autism. 4: 15. PMID 23706040 DOI: 10.1186/2040-2392-4-15  0.415
2013 Osterweil EK, Chuang SC, Chubykin AA, Sidorov M, Bianchi R, Wong RK, Bear MF. Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome. Neuron. 77: 243-50. PMID 23352161 DOI: 10.1016/J.Neuron.2012.01.034  0.402
2012 Osterweil EK, Kind PC, Bear MF. Lifting the mood on treating fragile X. Biological Psychiatry. 72: 895-7. PMID 23121869 DOI: 10.1016/J.Biopsych.2012.09.017  0.392
2011 Auerbach BD, Osterweil EK, Bear MF. Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature. 480: 63-8. PMID 22113615 DOI: 10.1038/Nature10658  0.489
2011 Krueger DD, Osterweil EK, Chen SP, Tye LD, Bear MF. Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2587-92. PMID 21262808 DOI: 10.1073/Pnas.1013855108  0.413
2010 Osterweil EK, Krueger DD, Reinhold K, Bear MF. Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15616-27. PMID 21084617 DOI: 10.1523/Jneurosci.3888-10.2010  0.46
2010 Krueger DD, Osterweil EK, Bear MF. Activation of mGluR5 induces rapid and long-lasting protein kinase D phosphorylation in hippocampal neurons. Journal of Molecular Neuroscience : Mn. 42: 1-8. PMID 20177824 DOI: 10.1007/S12031-010-9338-9  0.382
2008 Bear MF, Dölen G, Osterweil E, Nagarajan N. Fragile X: translation in action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 84-7. PMID 17940551 DOI: 10.1038/Sj.Npp.1301610  0.461
2007 Dölen G, Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF. Correction of fragile X syndrome in mice. Neuron. 56: 955-62. PMID 18093519 DOI: 10.1016/J.Neuron.2007.12.001  0.422
2007 Krendel M, Osterweil EK, Mooseker MS. Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. Febs Letters. 581: 644-50. PMID 17257598 DOI: 10.1016/J.Febslet.2007.01.021  0.458
2005 Osterweil E, Wells DG, Mooseker MS. A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. The Journal of Cell Biology. 168: 329-38. PMID 15657400 DOI: 10.1083/Jcb.200410091  0.552
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