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Hoang V. Le, Ph.D. - Publications

Affiliations: 
2008 Chemistry University of California, Berkeley, Berkeley, CA, United States 
 2013 Chemistry and Chemical Biology Cornell University, Ithaca, NY, United States 
 2016 Chemistry Northwestern University, Evanston, IL 
 2016- BioMolecular Sciences University of Missisippi School of Pharmacy 
Area:
Medicinal Chemistry and Enzymology
Website:
http://hlelab.com
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lykins J, Moschitto MJ, Zhou Y, Filippova EV, Le HV, Tomita T, Fox BA, Bzik DJ, Su C, Rajagopala SV, Flores K, Spano F, Woods S, Roberts CW, Hua C, et al. From O/GABA-AT, GABA, and T-263 Mutant to Conception of . Iscience. 27: 108477. PMID 38205261 DOI: 10.1016/j.isci.2023.108477  0.482
2023 Kdimy A, Kim SJ, Ali Z, Khan MIH, Tripathi SK, El Hajjaji S, Le HV. Isolation of Two Plasticizers, Bis(2-Ethylhexyl) Terephthalate and Bis(2-Ethylhexyl) Phthalate, from Capparis spinosa L. Leaves. Chemistry & Biodiversity. e202300903. PMID 37505806 DOI: 10.1002/cbdv.202300903  0.7
2023 Akins NS, Salahuddin MF, Pandey P, Kim SJ, Mahdi F, Khan MIH, Moss EM, Worth CJ, Keane MM, Chittiboyina AG, Doerksen RJ, Paris JJ, Le HV. Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-Based Antagonists and Kappa Opioid Receptor. Acs Chemical Neuroscience. PMID 36795782 DOI: 10.1021/acschemneuro.2c00806  0.722
2022 Khan MIH, Mahdi F, Penfornis P, Akins NS, Hossain MI, Kim SJ, Sulochana SP, Adam AT, Tran TD, Tan C, Paolo Claudio P, Paris JJ, Le HV. Synthesis and biological evaluation of tert-butyl ester and ethyl ester prodrugs of L-γ-methyleneglutamic acid amides for cancer. Bioorganic & Medicinal Chemistry. 78: 117137. PMID 36603398 DOI: 10.1016/j.bmc.2022.117137  0.715
2022 Khan MIH, Sawyer BJ, Akins NS, Le HV. A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse. European Journal of Medicinal Chemistry. 243: 114785. PMID 36179400 DOI: 10.1016/j.ejmech.2022.114785  0.712
2022 Hossain MI, Khan MIH, Kim SJ, Le HV. Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, β-ketoesters, or β-ketoamides. Beilstein Journal of Organic Chemistry. 18: 446-458. PMID 35529890 DOI: 10.3762/bjoc.18.47  0.715
2020 Xu J, Chen F, Wang S, Akins NS, Hossain MI, Zhou Y, Huang J, Ji J, Xi J, Lin W, Grothusen J, Le HV, Liu R. Kappa opioid receptors internalization is protective against oxygen-glucose deprivation through β-arrestin activation and Akt-mediated signaling pathway. Neurochemistry International. 104748. PMID 32339667 DOI: 10.1016/J.Neuint.2020.104748  0.3
2018 Juncosa JI, Takaya K, Le HV, Moschitto MJ, Weerawarna PM, Mascarenhas R, Liu D, Dewey SL, Silverman RB. Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction. Journal of the American Chemical Society. PMID 29381352 DOI: 10.1021/Jacs.7B10965  0.704
2017 Mascarenhas R, Le HV, Clevenger KD, Lehrer HJ, Ringe D, Kelleher NL, Silverman RB, Liu D. Correction to Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. Biochemistry. PMID 29045130 DOI: 10.1021/Acs.Biochem.7B00961  0.456
2017 Mascarenhas R, Le HV, Clevenger KD, Lehrer HJ, Ringe D, Kelleher NL, Silverman RB, Liu D. Selective Targeting by a Mechanism-based Inactivator against PLP-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. Biochemistry. PMID 28816437 DOI: 10.1021/Acs.Biochem.7B00499  0.559
2017 Wu R, Sanishvili R, Belitsky BR, Juncosa JI, Le HV, Lehrer HJ, Farley M, Silverman RB, Petsko GA, Ringe D, Liu D. PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348215 DOI: 10.1073/Pnas.1703019114  0.746
2015 Shin MW, Bae SJ, Wee HJ, Lee HJ, Ahn BJ, Le H, Lee EJ, Kim RH, Lee HS, Seo JH, Park JH, Kim KW. Ninjurin1 regulates lipopolysaccharide-induced inflammation through direct binding. International Journal of Oncology. PMID 26677008 DOI: 10.3892/ijo.2015.3296  0.375
2015 Zigmond E, Ya'acov AB, Lee H, Lichtenstein Y, Shalev Z, Smith Y, Zolotarov L, Ziv E, Kalman R, Le HV, Lu H, Silverman RB, Ilan Y. Suppression of Hepatocellular Carcinoma by Inhibition of Overexpressed Ornithine Aminotransferase. Acs Medicinal Chemistry Letters. 6: 840-844. PMID 26288681 DOI: 10.1021/Acsmedchemlett.5B00153  0.485
2015 Lee H, Le HV, Wu R, Doud E, Sanishvili R, Kellie JF, Compton PD, Pachaiyappan B, Liu D, Kelleher NL, Silverman RB. Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chemical Biology. PMID 26110556 DOI: 10.1021/Acschembio.5B00212  0.616
2015 Le HV, Hawker DD, Wu R, Doud E, Widom J, Sanishvili R, Liu D, Kelleher NL, Silverman RB. Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators. Journal of the American Chemical Society. 137: 4525-33. PMID 25781189 DOI: 10.1021/Jacs.5B01155  0.764
2014 Le HV, Ganem B. Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry. Tetrahedron Letters. 55: 2003-2005. PMID 24791030 DOI: 10.1016/J.Tetlet.2014.02.016  0.581
2012 Le HV, Ganem B. A Practical Synthesis of Isocyanates from Isonitriles: Ethyl 2-Isocyanatoacetate. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 89: 404-408. PMID 35782717 DOI: 10.15227/orgsyn.089.0404  0.422
2012 Gober CM, Le HV, Ganem B. A Simple, General Synthesis of Carbonimidic Dichlorides. Tetrahedron Letters. 53: 4536-4537. PMID 22865938 DOI: 10.1016/J.Tetlet.2012.06.046  0.557
2012 Le HV, Ganem B. A practical synthesis of isocyanates from isonitriles: Ethyl 2-isocyanatoacetate Organic Syntheses. 89: 404-408. DOI: 10.1002/0471264229.Os089.38  0.477
2011 Sanguineti G, Le HV, Ganem B. Studies on the synthesis of amidoximes from nitroalkanes. Tetrahedron. 67: 10208-10211. PMID 22247575 DOI: 10.1016/J.Tet.2011.09.147  0.514
2011 Le HV, Ganem B. Trifluoroacetic anhydride-catalyzed oxidation of isonitriles by DMSO: a rapid, convenient synthesis of isocyanates. Organic Letters. 13: 2584-5. PMID 21491899 DOI: 10.1021/Ol200695Y  0.502
2011 Le HV, Fan L, Ganem B. A practical and inexpensive 'convertible' isonitrile for use in multicomponent reactions Tetrahedron Letters. 52: 2209-2211. DOI: 10.1016/J.Tetlet.2010.11.156  0.626
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