Year |
Citation |
Score |
2017 |
Tran TA, Kramer B, Shin YJ, Vallar P, Boatman PD, Zou N, Sage CR, Gharbaoui T, Krishnan A, Pal B, Shakya SR, Garrido Montalban A, Adams JW, Ramirez J, Behan DP, et al. Discovery of 2-(((1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag) :An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension. Journal of Medicinal Chemistry. PMID 28072531 DOI: 10.1021/Acs.Jmedchem.6B00871 |
0.309 |
|
2015 |
Tran TA, Shin YJ, Kramer B, Choi J, Zou N, Vallar P, Martens P, Boatman PD, Adams JW, Ramirez J, Shi Y, Morgan M, Unett DJ, Chang S, Shu HH, et al. Discovery of a new series of potent prostacyclin receptor agonists with in vivo activity in rat. Bioorganic & Medicinal Chemistry Letters. 25: 1030-5. PMID 25666818 DOI: 10.1016/J.Bmcl.2015.01.024 |
0.328 |
|
2012 |
Semple G, Lehmann J, Wong A, Ren A, Bruce M, Shin YJ, Sage CR, Morgan M, Chen WC, Sebring K, Chu ZL, Leonard JN, Al-Shamma H, Grottick AJ, Du F, et al. Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile. Bioorganic & Medicinal Chemistry Letters. 22: 1750-5. PMID 22264481 DOI: 10.1016/J.Bmcl.2011.12.092 |
0.313 |
|
2011 |
Semple G, Ren A, Fioravanti B, Pereira G, Calderon I, Choi K, Xiong Y, Shin YJ, Gharbaoui T, Sage CR, Morgan M, Xing C, Chu ZL, Leonard JN, Grottick AJ, et al. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorganic & Medicinal Chemistry Letters. 21: 3134-41. PMID 21444206 DOI: 10.1016/J.Bmcl.2011.03.007 |
0.312 |
|
2007 |
Skinner PJ, Cherrier MC, Webb PJ, Shin YJ, Gharbaoui T, Lindstrom A, Hong V, Tamura SY, Dang HT, Pride CC, Chen R, Richman JG, Connolly DT, Semple G. Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a. Bioorganic & Medicinal Chemistry Letters. 17: 5620-3. PMID 17804224 DOI: 10.1016/J.Bmcl.2007.07.101 |
0.365 |
|
2007 |
Gharbaoui T, Skinner PJ, Shin YJ, Averbuj C, Jung JK, Johnson BR, Duong T, Decaire M, Uy J, Cherrier MC, Webb PJ, Tamura SY, Zou N, Rodriguez N, Boatman PD, et al. Agonist lead identification for the high affinity niacin receptor GPR109a. Bioorganic & Medicinal Chemistry Letters. 17: 4914-9. PMID 17588745 DOI: 10.1016/J.Bmcl.2007.06.028 |
0.346 |
|
2002 |
Hyun MH, Han SC, Lipshutz BH, Shin YJ, Welch CJ. Liquid chromatographic resolution of racemic amines, amino alcohols and related compounds on a chiral crown ether stationary phase. Journal of Chromatography. A. 959: 75-83. PMID 12141563 DOI: 10.1016/S0021-9673(02)00431-4 |
0.466 |
|
2001 |
Hyun MH, Han SC, Lipshutz BH, Shin YJ, Welch CJ. New chiral crown ether stationary phase for the liquid chromatographic resolution of alpha-amino acid enantiomers. Journal of Chromatography. A. 910: 359-65. PMID 11261730 DOI: 10.1016/S0021-9673(00)01230-9 |
0.465 |
|
2001 |
Lipshutz BH, Shin YJ. A new silyl linker for reverse-direction solid-phase peptide synthesis Tetrahedron Letters. 42: 5629-5633. DOI: 10.1016/S0040-4039(01)01093-0 |
0.449 |
|
2000 |
Lipshutz BH, Shin YJ. Polystyrene-bound cyclo-BINOLs. New heterogeneous ligands for asymmetric catalysis Tetrahedron Letters. 41: 9515-9521. DOI: 10.1016/S0040-4039(00)01660-9 |
0.453 |
|
1998 |
Lipshutz BH, Shin YJ. A modular approach to nonracemic cyclo-BINOLs. Preparation of symmetrically and unsymmetrically substituted ligands Tetrahedron Letters. 39: 7017-7020. DOI: 10.1016/S0040-4039(98)01468-3 |
0.451 |
|
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