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Immaculada Silos-Santiago - Publications

Affiliations: 
Vertex Pharmaceuticals, Boston, MA, United States 
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Levanti MB, Esteban I, Ciriaco E, Pérez-Piñera P, Cabo R, García-Suarez O, Pardo B, Silos-Santiago I, Cobo J, Vega JA. Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development. Neuroscience Letters. 454: 16-21. PMID 19429046 DOI: 10.1016/j.neulet.2009.02.051  0.313
2008 Perez-Pinera P, García-Suarez O, Germanà A, Díaz-Esnal B, de Carlos F, Silos-Santiago I, del Valle ME, Cobo J, Vega JA. Characterization of sensory deficits in TrkB knockout mice. Neuroscience Letters. 433: 43-7. PMID 18248898 DOI: 10.1016/j.neulet.2007.12.035  0.456
2006 de Carlos F, Cobo J, Germanà G, Silos-Santiago I, Laurà R, Haro JJ, Fariñas I, Vega JA. Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice. Neuroscience Letters. 410: 157-61. PMID 17101216 DOI: 10.1016/j.neulet.2006.07.056  0.36
2004 Ichikawa H, Matsuo S, Silos-Santiago I, Jacquin MF, Sugimoto T. The development of myelinated nociceptors is dependent upon trks in the trigeminal ganglion. Acta Histochemica. 106: 337-43. PMID 15530548 DOI: 10.1016/j.acthis.2004.07.003  0.426
2003 Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T, Curtis R. Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7577-85. PMID 12930796  0.54
2003 Holm PC, Rodríguez FJ, Kresse A, Canals JM, Silos-Santiago I, Arenas E. Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Development (Cambridge, England). 130: 3535-45. PMID 12810600 DOI: 10.1242/Dev.00565  0.459
2003 Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T, Curtis R. Sodium Channel β4, a New Disulfide-Linked Auxiliary Subunit with Similarity to β2 The Journal of Neuroscience. 23: 7577-7585. DOI: 10.1523/JNEUROSCI.23-20-07577.2003  0.391
2002 Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature. 418: 181-6. PMID 12077604 DOI: 10.1038/Nature00882  0.441
2002 de Vicente JC, Cabo R, Ciriaco E, Laurà R, Naves FJ, Silos-Santiago I, Vega JA. Impaired dental cytodifferentiation in glial cell-line derived growth factor (GDNF) deficient mice. Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. 184: 85-92. PMID 11878293 DOI: 10.1016/S0940-9602(02)80041-3  0.358
2001 Qu Y, Curtis R, Lawson D, Gilbride K, Ge P, DiStefano PS, Silos-Santiago I, Catterall WA, Scheuer T. Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits. Molecular and Cellular Neurosciences. 18: 570-80. PMID 11922146 DOI: 10.1006/Mcne.2001.1039  0.572
2001 Matsuo S, Ichikawa H, Henderson TA, Silos-Santiago I, Barbacid M, Arends JJ, Jacquin MF. trkA modulation of developing somatosensory neurons in oro-facial tissues: tooth pulp fibers are absent in trkA knockout mice. Neuroscience. 105: 747-60. PMID 11516838 DOI: 10.1016/S0306-4522(01)00223-8  0.328
2000 Weiger TM, Holmqvist MH, Levitan IB, Clark FT, Sprague S, Huang WJ, Ge P, Wang C, Lawson D, Jurman ME, Glucksmann MA, Silos-Santiago I, DiStefano PS, Curtis R. A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3563-70. PMID 10804197 DOI: 10.1523/Jneurosci.20-10-03563.2000  0.447
2000 Matsuo S, Ichikawa H, Silos-Santiago I, Arends JJ, Henderson TA, Kiyomiya K, Kurebe M, Jacquin MF. Proprioceptive afferents survive in the masseter muscle of trkC knockout mice. Neuroscience. 95: 209-16. PMID 10619477 DOI: 10.1016/S0306-4522(99)00424-8  0.352
1998 Fritzsch B, Barbacid M, Silos-Santiago I. Nerve dependency of developing and mature sensory receptor cells. Annals of the New York Academy of Sciences. 855: 14-27. PMID 9929583 DOI: 10.1111/J.1749-6632.1998.Tb10543.X  0.375
1998 Fritzsch B, Barbacid M, Silos-Santiago I. The combined effects of trkB and trkC mutations on the innervation of the inner ear. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 16: 493-505. PMID 9881298 DOI: 10.1016/S0736-5748(98)00043-4  0.323
1998 de Castro F, Silos-Santiago I, López de Armentia M, Barbacid M, Belmonte C. Corneal innervation and sensitivity to noxious stimuli in trkA knockout mice. The European Journal of Neuroscience. 10: 146-52. PMID 9753121 DOI: 10.1046/J.1460-9568.1998.00037.X  0.379
1998 Rice FL, Albers KM, Davis BM, Silos-Santiago I, Wilkinson GA, LeMaster AM, Ernfors P, Smeyne RJ, Aldskogius H, Phillips HS, Barbacid M, DeChiara TM, Yancopoulos GD, Dunne CE, Fundin BT. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. Developmental Biology. 198: 57-81. PMID 9640332 DOI: 10.1006/Dbio.1998.8861  0.374
1997 Fritzsch B, Silos-Santiago I, Bianchi LM, Farinas I. Effects of neurotrophin and neurotrophin receptor disruption on the afferent inner ear innervation. Seminars in Cell & Developmental Biology. 8: 277-84. PMID 11542690  0.395
1997 Fritzsch B, Silos-Santiago I, Bianchi LM, Fariñas I. Effects of neurotrophin and neurotrophin receptor disruption on the afferent inner ear innervation. Seminars in Cell & Developmental Biology. 8: 277-284. PMID 10024490 DOI: 10.1006/Scdb.1997.0144  0.395
1997 Silos-Santiago I, Fagan AM, Garber M, Fritzsch B, Barbacid M. Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors. The European Journal of Neuroscience. 9: 2045-56. PMID 9421165 DOI: 10.1111/J.1460-9568.1997.Tb01372.X  0.338
1997 Fundin BT, Silos-Santiago I, Ernfors P, Fagan AM, Aldskogius H, DeChiara TM, Phillips HS, Barbacid M, Yancopoulos GD, Rice FL. Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Developmental Biology. 190: 94-116. PMID 9331334 DOI: 10.1006/Dbio.1997.8658  0.344
1997 Fagan AM, Garber M, Barbacid M, Silos-Santiago I, Holtzman DM. A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7644-54. PMID 9315886 DOI: 10.1523/Jneurosci.17-20-07644.1997  0.461
1997 Alcántara S, Frisén J, del Río JA, Soriano E, Barbacid M, Silos-Santiago I. TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3623-33. PMID 9133385 DOI: 10.1523/Jneurosci.17-10-03623.1997  0.435
1997 Fritzsch B, Silos-Santiago I, Bianchi LM, Fariñas I. The role of neurotrophic factors in regulating the development of inner ear innervation. Trends in Neurosciences. 20: 159-64. PMID 9106356 DOI: 10.1016/S0166-2236(96)01007-7  0.367
1996 Silos-Santiago I, Yeh HJ, Gurrieri MA, Guillerman RP, Li YS, Wolf J, Snider W, Deuel TF. Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neural-glial interactions during development and in maturity. Journal of Neurobiology. 31: 283-96. PMID 8910787 DOI: 10.1002/(SICI)1097-4695(199611)31:3<283::AID-NEU2>3.0.CO;2-6  0.637
1996 Fagan AM, Zhang H, Landis S, Smeyne RJ, Silos-Santiago I, Barbacid M. TrkA, but not TrkC, receptors are essential for survival of sympathetic neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6208-18. PMID 8815902 DOI: 10.1523/Jneurosci.16-19-06208.1996  0.465
1996 White FA, Silos-Santiago I, Molliver DC, Nishimura M, Phillips H, Barbacid M, Snider WD. Synchronous onset of NGF and TrkA survival dependence in developing dorsal root ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4662-72. PMID 8764654 DOI: 10.1523/Jneurosci.16-15-04662.1996  0.733
1996 Snider WD, Silos-Santiago I. Dorsal root ganglion neurons require functional neurotrophin receptors for survival during development. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 395-403. PMID 8730777 DOI: 10.1098/rstb.1996.0034  0.679
1996 Sánchez MP, Silos-Santiago I, Frisén J, He B, Lira SA, Barbacid M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 382: 70-3. PMID 8657306 DOI: 10.1038/382070A0  0.41
1995 Wright DE, White FA, Gerfen RW, Silos-Santiago I, Snider WD. The guidance molecule semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons. The Journal of Comparative Neurology. 361: 321-33. PMID 8543665 DOI: 10.1002/Cne.903610209  0.698
1995 Silos-Santiago I, Greenlund LJ, Johnson EM, Snider WD. Molecular genetics of neuronal survival. Current Opinion in Neurobiology. 5: 42-9. PMID 7773004 DOI: 10.1016/0959-4388(95)80085-9  0.653
1995 Silos-Santiago I, Molliver DC, Ozaki S, Smeyne RJ, Fagan AM, Barbacid M, Snider WD. Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5929-42. PMID 7666178 DOI: 10.1523/Jneurosci.15-09-05929.1995  0.742
1995 Konstantinidou AD, Silos-Santiago I, Flaris N, Snider WD. Development of the primary afferent projection in human spinal cord. The Journal of Comparative Neurology. 354: 11-2. PMID 7615870 DOI: 10.1002/cne.903540102  0.588
1995 Silos-Santiago I, Jeng B, Snider WD. Sensory afferents show appropriate somatotopy at the earliest stage of projection to dorsal horn. Neuroreport. 6: 861-5. PMID 7612871  0.58
1994 Silos-Santiago I, Snider WD. Development of interneurons with ipsilateral projections in embryonic rat spinal cord. The Journal of Comparative Neurology. 342: 221-31. PMID 8201033 DOI: 10.1002/cne.903420206  0.614
1994 Klein R, Silos-Santiago I, Smeyne RJ, Lira SA, Brambilla R, Bryant S, Zhang L, Snider WD, Barbacid M. Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements. Nature. 368: 249-51. PMID 8145824 DOI: 10.1038/368249A0  0.637
1993 Yeh HJ, Silos-Santiago I, Wang YX, George RJ, Snider WD, Deuel TF. Developmental expression of the platelet-derived growth factor alpha-receptor gene in mammalian central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 90: 1952-6. PMID 8446614  0.64
1993 Mu X, Silos-Santiago I, Carroll SL, Snider WD. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4029-41. PMID 8366358  0.681
1992 Silos-Santiago I, Snider WD. Development of commissural neurons in the embryonic rat spinal cord. The Journal of Comparative Neurology. 325: 514-26. PMID 1469113 DOI: 10.1002/cne.903250405  0.623
1992 Carroll SL, Silos-Santiago I, Frese SE, Ruit KG, Milbrandt J, Snider WD. Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero. Neuron. 9: 779-88. PMID 1389185 DOI: 10.1016/0896-6273(92)90040-K  0.67
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