Gerard Karsenty, Md - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Cellular/Molecular/Developmental Neuroscience

286 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Correa Pinto Junior D, Canal Delgado I, Yang H, Clemenceau A, Corvelo A, Narzisi G, Musunuri R, Meyer Berger J, Hendricks LE, Tokumura K, Luo N, Li H, Oury F, Ducy P, Yadav VK, ... ... Karsenty G, et al. Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring. Embo Reports. PMID 38228788 DOI: 10.1038/s44319-023-00031-3  0.741
2023 Kim YK, Kim YR, Wells KL, Sarbaugh D, Guney M, Tsai CF, Zee T, Karsenty G, Nakayasu ES, Sussel L. PTPN2 regulates metabolic flux to affect beta cell susceptibility to inflammatory stress. Diabetes. PMID 38015772 DOI: 10.2337/db23-0355  0.745
2023 Pinto DC, Delgado IC, Yang H, Clemenceau A, Corvelo A, Narzisi G, Musunuri R, Berger JM, Hendricks LE, Tokumura K, Luo N, Li H, Oury F, Ducy P, Yadav VK, ... ... Karsenty G, et al. Osteocalcin of maternal and embryonic origins synergize to establish homeostasis in offspring. Biorxiv : the Preprint Server For Biology. PMID 37645714 DOI: 10.1101/2023.08.11.552969  0.74
2023 Karsenty G. Osteocalcin: A Multifaceted Bone-Derived Hormone. Annual Review of Nutrition. 43: 55-71. PMID 37603430 DOI: 10.1146/annurev-nutr-061121-091348  0.349
2023 Palmisano B, Riminucci M, Karsenty G. Interleukin-6 signaling in osteoblasts regulates bone remodeling during exercise. Bone. 176: 116870. PMID 37586472 DOI: 10.1016/j.bone.2023.116870  0.37
2022 Karsenty G, Khosla S. The crosstalk between bone remodeling and energy metabolism: A translational perspective. Cell Metabolism. PMID 35545088 DOI: 10.1016/j.cmet.2022.04.010  0.424
2021 Berger JM, Karsenty G. Osteocalcin and the physiology of danger. Febs Letters. PMID 34913486 DOI: 10.1002/1873-3468.14259  0.404
2021 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G. Embryonic osteocalcin signalling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. The Journal of Clinical Investigation. PMID 34905510 DOI: 10.1172/JCI153752  0.652
2021 Karsenty G. Bone marrow runs the (bone) show. The Journal of Experimental Medicine. 218. PMID 34705037 DOI: 10.1084/jem.20211996  0.353
2020 Roberts FL, Rashdan NA, Phadwal K, Markby GR, Dillon S, Zoll J, Berger J, Milne E, Orriss IR, Karsenty G, Le Saux O, Morton NM, Farquharson C, MacRae VE. Osteoblast-specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase-1 engenders insulin resistance in high-fat diet fed mice. Journal of Cellular Physiology. PMID 33305372 DOI: 10.1002/jcp.30194  0.327
2020 Suchacki KJ, Morton NM, Vary C, Huesa C, Yadav MC, Thomas BJ, Turban S, Bunger L, Ball D, Barrios-Llerena ME, Guntur AR, Khavandgar Z, Cawthorn WP, Ferron M, Karsenty G, et al. PHOSPHO1 is a skeletal regulator of insulin resistance and obesity. Bmc Biology. 18: 149. PMID 33092598 DOI: 10.1186/s12915-020-00880-7  0.813
2020 Karsenty G. The Central Regulation of Bone Mass: Genetic Evidence and Molecular Bases. Handbook of Experimental Pharmacology. PMID 32960342 DOI: 10.1007/164_2020_378  0.523
2020 Karsenty G. That Feeling in Your Bones. Cerebrum : the Dana Forum On Brain Science. 2020. PMID 32802269  0.379
2020 Chowdhury S, Schulz LC, Palmisano B, Singh P, Berger JM, Yadav VK, Mera P, Ellingsgaard H, Hidalgo J, Brüning JC, Karsenty G. Muscle derived interleukin-6 increases exercise capacity by signaling in osteoblasts. The Journal of Clinical Investigation. PMID 32078586 DOI: 10.1172/Jci133572  0.577
2020 Lacombe J, Al Rifai O, Loter L, Moran T, Turcotte AF, Grenier-Larouche T, Tchernof A, Biertho L, Carpentier AC, Prud'homme D, Rabasa-Lhoret R, Karsenty G, Gagnon C, Jiang W, Ferron M. Measurement of bioactive osteocalcin in humans using a novel immunoassay reveals association with glucose metabolism and β-cell function. American Journal of Physiology. Endocrinology and Metabolism. PMID 31935114 DOI: 10.1152/Ajpendo.00321.2019  0.655
2019 Rashdan NA, Sim AM, Cui L, Phadwal K, Roberts FL, Carter R, Ozdemir DD, Hohenstein P, Hung J, Kaczynski J, Newby DE, Baker AH, Karsenty G, Morton NM, MacRae VE. Osteocalcin Regulates Arterial Calcification via Altered Wnt Signalling and Glucose Metabolism. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31596966 DOI: 10.1002/Jbmr.3888  0.346
2019 Berger JM, Singh P, Khrimian L, Morgan DA, Chowdhury S, Arteaga-Solis E, Horvath TL, Domingos AI, Marsland AL, Kumal Yadav V, Rahmouni K, Gao XB, Karsenty G. Mediation of the Acute Stress Response by the Skeleton. Cell Metabolism. PMID 31523009 DOI: 10.1016/J.Cmet.2019.08.012  0.433
2019 Ferron M, Lacombe J, Germain A, Oury F, Karsenty G. Correction: GGCX and VKORC1 inhibit osteocalcin endocrine functions. The Journal of Cell Biology. PMID 31040164 DOI: 10.1083/Jcb.20140911104082019C  0.746
2019 Jacome-Galarza CE, Percin GI, Muller JT, Mass E, Lazarov T, Eitler J, Rauner M, Yadav VK, Crozet L, Bohm M, Loyher PL, Karsenty G, Waskow C, Geissmann F. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. PMID 30971820 DOI: 10.1038/S41586-019-1105-7  0.73
2019 Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, et al. Publisher Correction: Serotonin signals through a gut-liver axis to regulate hepatic steatosis. Nature Communications. 10: 158. PMID 30622275 DOI: 10.1038/S41467-018-08085-X  0.588
2019 Chen Y, Berger J, Karsenty G. MON-LB086 Single-Cell Transcriptional Profiling of Bone Cells Reveals Diversity of Osteoblasts Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-Lb086  0.475
2018 Kim H, Kim YG, Choi W, Moon JH, Hwang I, Kim K, Yadav VK, Karsenty G, Jeong JS, Kim H. Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Scientific Reports. 8: 17642. PMID 30518775 DOI: 10.1038/S41598-018-36097-6  0.606
2018 Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, et al. Serotonin signals through a gut-liver axis to regulate hepatic steatosis. Nature Communications. 9: 4824. PMID 30446669 DOI: 10.1038/S41467-018-07287-7  0.592
2018 Obri A, Khrimian L, Karsenty G, Oury F. Osteocalcin in the brain: from embryonic development to age-related decline in cognition. Nature Reviews. Endocrinology. PMID 29376523 DOI: 10.1038/Nrendo.2017.181  0.314
2018 Ducy PF, Karsenty G. Endocrine Bioenergetics of Bone Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 1012-1019. DOI: 10.1002/9781119266594.Ch130  0.74
2017 Khrimian L, Obri A, Karsenty G. Modulation of cognition and anxiety-like behavior by bone remodeling. Molecular Metabolism. 6: 1610-1615. PMID 29157601 DOI: 10.1016/J.Molmet.2017.10.001  0.404
2017 Bailey S, Karsenty G, Gundberg C, Vashishth D. Osteocalcin and osteopontin influence bone morphology and mechanical properties. Annals of the New York Academy of Sciences. PMID 29044594 DOI: 10.1111/Nyas.13470  0.508
2017 Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G. Gpr158 mediates osteocalcin's regulation of cognition. The Journal of Experimental Medicine. PMID 28851741 DOI: 10.1084/Jem.20171320  0.308
2017 Karsenty G. UPDATE ON THE BIOLOGY OF OSTEOCALCIN. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. PMID 28704102 DOI: 10.4158/EP171966.RA  0.394
2017 Penafuerte C, Feldhammer M, Mills JR, Vinette V, Pike KA, Hall A, Migon E, Karsenty G, Pelletier J, Zogopoulos G, Tremblay ML. Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNγ signaling. Oncoimmunology. 6: e1321185. PMID 28680757 DOI: 10.1080/2162402X.2017.1321185  0.303
2017 Matsumoto Y, La Rose J, Lim M, Adissu HA, Law N, Mao X, Cong F, Mera P, Karsenty G, Goltzman D, Changoor A, Zhang L, Stajkowski M, Grynpas MD, Bergmann C, et al. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. The Journal of Clinical Investigation. PMID 28581440 DOI: 10.1172/Jci92233  0.539
2017 Karsenty G, Mera P. Molecular bases of the crosstalk between bone and muscle. Bone. PMID 28428077 DOI: 10.1016/J.Bone.2017.04.006  0.361
2017 Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, ... ... Karsenty G, et al. Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. Cell Metabolism. 25: 218. PMID 28076763 DOI: 10.1016/J.Cmet.2016.12.003  0.61
2016 Liu JM, Rosen CJ, Ducy P, Kousteni S, Karsenty G. Regulation of Glucose Handling by the Skeleton: Insights From Mouse and Human Studies. Diabetes. 65: 3225-3232. PMID 27959858 DOI: 10.2337/Db16-0053  0.759
2016 Mera P, Laue K, Wei J, Berger JM, Karsenty G. Osteocalcin is necessary and sufficient to maintain muscle mass in older mice. Molecular Metabolism. 5: 1042-7. PMID 27689017 DOI: 10.1016/J.Molmet.2016.07.002  0.348
2016 Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR. Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5). The Journal of Biological Chemistry. 291: 16878. PMID 27496960 DOI: 10.1074/Jbc.A111.337048  0.72
2016 Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, ... ... Karsenty G, et al. Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. Cell Metabolism. 23: 1078-1092. PMID 27304508 DOI: 10.1016/J.Cmet.2016.05.004  0.649
2016 Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, ... Karsenty G, et al. Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. Cell. PMID 27133169 DOI: 10.1016/J.Cell.2016.03.033  0.308
2016 Shimazu J, Wei J, Karsenty G. Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148. Cell Reports. PMID 27052174 DOI: 10.1016/J.Celrep.2016.03.003  0.537
2016 Karsenty G, Olson EN. Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication. Cell. 164: 1248-56. PMID 26967290 DOI: 10.1016/J.Cell.2016.02.043  0.364
2015 Wei J, Flaherty S, Karsenty G. Searching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics. Expert Review of Endocrinology & Metabolism. 10: 413-424. PMID 27588033 DOI: 10.1586/17446651.2015.1058152  0.392
2015 Zhang F, Xu L, Xu L, Xu Q, Karsenty G, Chen CD. Histone demethylase JMJD3 is required for osteoblast differentiation in mice. Scientific Reports. 5: 13418. PMID 26302868 DOI: 10.1038/Srep13418  0.544
2015 Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Lezaki T, Pessin JE, Hinoi E, Karsenty G. Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell. 161: 1576-91. PMID 26091038 DOI: 10.1016/J.Cell.2015.05.029  0.84
2015 Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. The Journal of Clinical Investigation. 125: 2180. PMID 25932680 DOI: 10.1172/JCI81812  0.723
2015 Abdallah BM, Ditzel N, Laborda J, Karsenty G, Kassem M. DLK1 Regulates Whole-Body Glucose Metabolism: A Negative Feedback Regulation of the Osteocalcin-Insulin Loop. Diabetes. 64: 3069-80. PMID 25918236 DOI: 10.2337/Db14-1642  0.385
2015 Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, et al. Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nature Communications. 6: 6794. PMID 25864946 DOI: 10.1038/Ncomms7794  0.592
2015 Wei J, Karsenty G. An overview of the metabolic functions of osteocalcin. Current Osteoporosis Reports. 13: 180-5. PMID 25809656 DOI: 10.1007/S11914-015-0267-Y  0.516
2015 Ferron M, Lacombe J, Germain A, Oury F, Karsenty G. GGCX and VKORC1 inhibit osteocalcin endocrine functions. The Journal of Cell Biology. 208: 761-76. PMID 25753038 DOI: 10.1083/Jcb.201409111  0.803
2015 Makinistoglu MP, Karsenty G. The class II histone deacetylase HDAC4 regulates cognitive, metabolic and endocrine functions through its expression in osteoblasts. Molecular Metabolism. 4: 64-9. PMID 25685691 DOI: 10.1016/J.Molmet.2014.10.004  0.814
2015 Swanson CM, Shea SA, Stone KL, Cauley JA, Rosen CJ, Redline S, Karsenty G, Orwoll ES. Obstructive sleep apnea and metabolic bone disease: insights into the relationship between bone and sleep. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 199-211. PMID 25639209 DOI: 10.1002/Jbmr.2446  0.387
2015 Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, ... ... Karsenty G, et al. Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell. 160: 269-84. PMID 25594183 DOI: 10.1016/J.Cell.2014.11.042  0.429
2015 Zhang F, Xu L, Xu L, Xu Q, Li D, Yang Y, Karsenty G, Chen CD. JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice. Journal of Molecular Cell Biology. 7: 23-34. PMID 25587042 DOI: 10.1093/Jmcb/Mjv003  0.529
2015 Karsenty G. Re-tuning bone formation. The Journal of Experimental Medicine. 212: 3. PMID 25582313 DOI: 10.1084/Jem.2121Insight2  0.379
2015 Wei J, Karsenty G. An overview of the metabolic functions of osteocalcin. Reviews in Endocrine & Metabolic Disorders. 16: 93-8. PMID 25577163 DOI: 10.1007/S11154-014-9307-7  0.521
2015 Kim K, Oh CM, Ohara-Imaizumi M, Park S, Namkung J, Yadav VK, Tamarina NA, Roe MW, Philipson LH, Karsenty G, Nagamatsu S, German MS, Kim H. Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology. 156: 444-52. PMID 25426873 DOI: 10.1210/En.2014-1687  0.621
2015 Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Iezaki T, Pessin JE, Hinoi E, Karsenty G. Erratum:Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation (Cell (2015) 161 (1576-1591)) Cell. 162. DOI: 10.1016/J.Cell.2015.08.018  0.679
2014 Kode A, Obri A, Paone R, Kousteni S, Ducy P, Karsenty G. Lrp5 regulation of bone mass and serotonin synthesis in the gut. Nature Medicine. 20: 1228-9. PMID 25375916 DOI: 10.1038/Nm.3698  0.736
2014 Huesa C, Zhu D, Glover JD, Ferron M, Karsenty G, Milne EM, Millan JL, Ahmed SF, Farquharson C, Morton NM, MacRae VE. Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes. Disease Models & Mechanisms. 7: 1341-50. PMID 25368121 DOI: 10.1242/Dmm.017905  0.75
2014 Kajimura D, Paone R, Mann JJ, Karsenty G. Foxo1 regulates Dbh expression and the activity of the sympathetic nervous system in vivo. Molecular Metabolism. 3: 770-7. PMID 25353004 DOI: 10.1016/J.Molmet.2014.07.006  0.496
2014 Karsenty G. Broadening the role of osteocalcin in Leydig cells. Endocrinology. 155: 4115-6. PMID 25325424 DOI: 10.1210/En.2014-1703  0.506
2014 Obri A, Makinistoglu MP, Zhang H, Karsenty G. HDAC4 integrates PTH and sympathetic signaling in osteoblasts. The Journal of Cell Biology. 205: 771-80. PMID 24934156 DOI: 10.1083/Jcb.201403138  0.813
2014 Bornstein S, Brown SA, Le PT, Wang X, DeMambro V, Horowitz MC, MacDougald O, Baron R, Lotinun S, Karsenty G, Wei W, Ferron M, Kovacs CS, Clemmons D, Wan Y, et al. FGF-21 and skeletal remodeling during and after lactation in C57BL/6J mice. Endocrinology. 155: 3516-26. PMID 24914939 DOI: 10.1210/En.2014-1083  0.749
2014 Wei J, Ferron M, Clarke CJ, Hannun YA, Jiang H, Blaner WS, Karsenty G. Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation. The Journal of Clinical Investigation. 124: 1-13. PMID 24642469 DOI: 10.1172/Jci72323  0.689
2014 Riddle RC, Frey JL, Tomlinson RE, Ferron M, Li Y, DiGirolamo DJ, Faugere MC, Hussain MA, Karsenty G, Clemens TL. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. Molecular and Cellular Biology. 34: 1850-62. PMID 24591652 DOI: 10.1128/Mcb.00075-14  0.744
2014 Karsenty G, Oury F. Regulation of male fertility by the bone-derived hormone osteocalcin. Molecular and Cellular Endocrinology. 382: 521-6. PMID 24145129 DOI: 10.1016/J.Mce.2013.10.008  0.501
2014 Wei J, Hanna T, Suda N, Karsenty G, Ducy P. Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a. Diabetes. 63: 1021-31. PMID 24009262 DOI: 10.2337/Db13-0887  0.698
2014 Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Corrigendum: Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis Journal of Clinical Investigation. 124: 5522. DOI: 10.1172/JCI79293  0.393
2014 Kajimura D, Lee HW, Riley KJ, Arteaga-Solis E, Ferron M, Zhou B, Clarke CJ, Hannun YA, Depinho RA, Guo XE, Mann JJ, Karsenty G. Erratum: Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1 (Cell Metabolism (2013) 17 (901-915)) Cell Metabolism. 19. DOI: 10.1016/J.Cmet.2014.04.013  0.738
2014 Karsenty G. Bone as an Endocrine Organ Cellular Endocrinology in Health and Disease. 193-205. DOI: 10.1016/B978-0-12-408134-5.00012-3  0.387
2013 Lacombe J, Karsenty G, Ferron M. In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice. Molecular Metabolism. 2: 498-504. PMID 24327965 DOI: 10.1016/J.Molmet.2013.08.004  0.747
2013 Nohara K, Liu S, Meyers MS, Waget A, Ferron M, Karsenty G, Burcelin R, Mauvais-Jarvis F. Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice. The Journal of Endocrinology. 219: 259-68. PMID 24084835 DOI: 10.1530/Joe-13-0230  0.621
2013 Oury F, Khrimian L, Denny CA, Gardin A, Chamouni A, Goeden N, Huang YY, Lee H, Srinivas P, Gao XB, Suyama S, Langer T, Mann JJ, Horvath TL, Bonnin A, ... Karsenty G, et al. Maternal and offspring pools of osteocalcin influence brain development and functions. Cell. 155: 228-41. PMID 24074871 DOI: 10.1016/J.Cell.2013.08.042  0.372
2013 Lacombe J, Karsenty G, Ferron M. Regulation of lysosome biogenesis and functions in osteoclasts. Cell Cycle (Georgetown, Tex.). 12: 2744-52. PMID 23966172 DOI: 10.4161/Cc.25825  0.748
2013 Gillespie JR, Bush JR, Bell GI, Aubrey LA, Dupuis H, Ferron M, Kream B, DiMattia G, Patel S, Woodgett JR, Karsenty G, Hess DA, Beier F. GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 154: 3702-18. PMID 23904355 DOI: 10.1210/En.2013-1155  0.705
2013 Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. The Journal of Clinical Investigation. 123: 2421-33. PMID 23728177 DOI: 10.1172/Jci65952  0.732
2013 Kajimura D, Lee HW, Riley KJ, Arteaga-Solis E, Ferron M, Zhou B, Clarke CJ, Hannun YA, DePinho RA, Guo XE, Guo EX, Mann JJ, Karsenty G. Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metabolism. 17: 901-15. PMID 23684624 DOI: 10.1016/J.Cmet.2013.04.009  0.752
2013 Nohara K, Waraich RS, Liu S, Ferron M, Waget A, Meyers MS, Karsenty G, Burcelin R, Mauvais-Jarvis F. Developmental androgen excess programs sympathetic tone and adipose tissue dysfunction and predisposes to a cardiometabolic syndrome in female mice. American Journal of Physiology. Endocrinology and Metabolism. 304: E1321-30. PMID 23612996 DOI: 10.1152/Ajpendo.00620.2012  0.665
2013 Ferron M, Settembre C, Shimazu J, Lacombe J, Kato S, Rawlings DJ, Ballabio A, Karsenty G. A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts. Genes & Development. 27: 955-69. PMID 23599343 DOI: 10.1101/Gad.213827.113  0.839
2013 Takarada T, Hinoi E, Nakazato R, Ochi H, Xu C, Tsuchikane A, Takeda S, Karsenty G, Abe T, Kiyonari H, Yoneda Y. An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2064-9. PMID 23553905 DOI: 10.1002/Jbmr.1945  0.747
2013 Zee T, Boller S, Györy I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G. The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. Febs Letters. 587: 711-6. PMID 23395800 DOI: 10.1016/J.Febslet.2013.01.049  0.846
2013 Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Nakamichi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, ... ... Karsenty G, et al. Vitamin D receptor in osteoblasts is a negative regulator of bone mass control. Endocrinology. 154: 1008-20. PMID 23389957 DOI: 10.1210/En.2012-1542  0.522
2013 Watanabe T, Oyama T, Asada M, Harada D, Ito Y, Inagawa M, Suzuki Y, Sugano S, Katsube K, Karsenty G, Komori T, Kitagawa M, Asahara H. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development. Plos Genetics. 9: e1003132. PMID 23326237 DOI: 10.1371/Journal.Pgen.1003132  0.492
2013 Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metabolism. 17: 35-48. PMID 23312282 DOI: 10.1016/J.Cmet.2012.12.004  0.747
2013 Oldknow K, Yadav M, Rajoanah S, Huesa C, Bunger L, Ferron M, Karsenty G, MacRae V, Milan JL, Farquharson C. An emerging role of phospho1 in the regulation of energy metabolism Bone Abstracts. DOI: 10.1530/Boneabs.01.Oc6.6  0.639
2013 Huesa C, Morton NM, Ferron M, Karsenty G, Millan JL, Ahmed F, Farquharson C, MacRae VE. Deficiency of the bone mineralisation inhibitor NPP1 protects against obesity and diabetes Bone Abstracts. DOI: 10.1530/Boneabs.01.Oc6.2  0.684
2013 Ferron M, Oury F, Karsenty G. Energy Homeostasis and Neuronal Regulation of Bone Remodeling Genetics of Bone Biology and Skeletal Disease. 69-80. DOI: 10.1016/B978-0-12-387829-8.00005-6  0.693
2013 Karsenty G. Translational Endocrinology of Bone Translational Endocrinology of Bone 0.329
2012 Sumara G, Sumara O, Kim JK, Karsenty G. Gut-derived serotonin is a multifunctional determinant to fasting adaptation. Cell Metabolism. 16: 588-600. PMID 23085101 DOI: 10.1016/J.Cmet.2012.09.014  0.726
2012 Rizzoli R, Cooper C, Reginster JY, Abrahamsen B, Adachi JD, Brandi ML, Bruyère O, Compston J, Ducy P, Ferrari S, Harvey NC, Kanis JA, Karsenty G, Laslop A, Rabenda V, et al. Antidepressant medications and osteoporosis. Bone. 51: 606-13. PMID 22659406 DOI: 10.1016/J.Bone.2012.05.018  0.657
2012 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G. miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology. 197: 509-21. PMID 22564414 DOI: 10.1083/Jcb.201201057  0.504
2012 Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, ... Karsenty G, et al. Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 7433-8. PMID 22538810 DOI: 10.1073/Pnas.1109036109  0.71
2012 Karsenty G. The mutual dependence between bone and gonads. The Journal of Endocrinology. 213: 107-14. PMID 22407998 DOI: 10.1530/Joe-11-0452  0.489
2012 Arteaga-Solis E, Settembre C, Ballabio A, Karsenty G. Sulfatases are determinants of alveolar formation. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 253-60. PMID 22366163 DOI: 10.1016/J.Matbio.2012.02.001  0.661
2012 Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, Facchinetti V, Sabatini DM, Ballabio A. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. The Embo Journal. 31: 1095-108. PMID 22343943 DOI: 10.1038/Emboj.2012.32  0.777
2012 Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR. Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). The Journal of Biological Chemistry. 287: 12016-26. PMID 22337886 DOI: 10.1074/Jbc.M111.337048  0.719
2012 Karsenty G, Ferron M. The contribution of bone to whole-organism physiology. Nature. 481: 314-20. PMID 22258610 DOI: 10.1038/Nature10763  0.644
2012 Zee T, Settembre C, Levine RL, Karsenty G. T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts. Molecular and Cellular Biology. 32: 1080-8. PMID 22252315 DOI: 10.1128/Mcb.06279-11  0.821
2012 Karsenty G, Oury F. Biology without walls: the novel endocrinology of bone. Annual Review of Physiology. 74: 87-105. PMID 22077214 DOI: 10.1146/Annurev-Physiol-020911-153233  0.48
2012 Rosen C, Karsenty G, MacDougald O. Foreword: interactions between bone and adipose tissue and metabolism. Bone. 50: 429. PMID 22015817 DOI: 10.1016/J.Bone.2011.10.006  0.406
2012 Confavreux CB, Borel O, Lee F, Vaz G, Guyard M, Fadat C, Carlier MC, Chapurlat R, Karsenty G. Osteoid osteoma is an osteocalcinoma affecting glucose metabolism. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 23: 1645-50. PMID 21681611 DOI: 10.1007/S00198-011-1684-0  0.357
2012 Ferron M, McKee MD, Levine RL, Ducy P, Karsenty G. Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice. Bone. 50: 568-75. PMID 21550430 DOI: 10.1016/J.Bone.2011.04.017  0.777
2012 Wei J, Karsenty G. Bone as a site of insulin resistance in type 2 diabetes Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P74  0.334
2011 Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, ... Karsenty G, et al. Sympathetic control of bone mass regulated by osteopontin. Proceedings of the National Academy of Sciences of the United States of America. 108: 17767-72. PMID 21990347 DOI: 10.1073/Pnas.1109402108  0.737
2011 Karsenty G. Bone endocrine regulation of energy metabolism and male reproduction. Comptes Rendus Biologies. 334: 720-4. PMID 21943521 DOI: 10.1016/J.Crvi.2011.07.007  0.479
2011 Karsenty G. Regulation of male fertility by bone Cold Spring Harbor Symposia On Quantitative Biology. 76: 279-283. PMID 21859673 DOI: 10.1101/sqb.2011.76.010934  0.371
2011 Karsenty G, Gershon MD. The importance of the gastrointestinal tract in the control of bone mass accrual. Gastroenterology. 141: 439-42. PMID 21699800 DOI: 10.1053/J.Gastro.2011.06.011  0.484
2011 Inose H, Zhou B, Yadav VK, Guo XE, Karsenty G, Ducy P. Efficacy of serotonin inhibition in mouse models of bone loss. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2002-11. PMID 21608033 DOI: 10.1002/Jbmr.439  0.808
2011 Oury F, Karsenty G. Towards a serotonin-dependent leptin roadmap in the brain. Trends in Endocrinology and Metabolism: Tem. 22: 382-7. PMID 21602053 DOI: 10.1016/J.Tem.2011.04.006  0.414
2011 Kajimura D, Hinoi E, Ferron M, Kode A, Riley KJ, Zhou B, Guo XE, Karsenty G. Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual. The Journal of Experimental Medicine. 208: 841-51. PMID 21444660 DOI: 10.1084/Jem.20102608  0.823
2011 Clemens TL, Karsenty G. The osteoblast: an insulin target cell controlling glucose homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 677-80. PMID 21433069 DOI: 10.1002/Jbmr.321  0.473
2011 Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G. Endocrine regulation of male fertility by the skeleton. Cell. 144: 796-809. PMID 21333348 DOI: 10.1016/J.Cell.2011.02.004  0.839
2011 Yadav VK, Oury F, Tanaka KF, Tanaka K, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. The Journal of Experimental Medicine. 208: 41-52. PMID 21187319 DOI: 10.1084/Jem.20101940  0.643
2011 Karsenty G, Yadav VK. Regulation of bone mass by serotonin: molecular biology and therapeutic implications. Annual Review of Medicine. 62: 323-31. PMID 21073335 DOI: 10.1146/Annurev-Med-090710-133426  0.712
2011 Yadav VK, Oury F, Tanaka KF, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: Temporal specificity, transcriptional regulation, and therapeutic implications (The Journal of Experimental Medicine (2011) 208, 1, (41-52)) Journal of Experimental Medicine. 208: 413. DOI: 10.1084/Jem.201019402082C  0.616
2011 Karsenty G. What makes an osteoclast special? Developmental Cell. 20: e2. DOI: 10.1016/J.Devcel.2011.05.005  0.384
2010 Karsenty G, Oury F. The central regulation of bone mass, the first link between bone remodeling and energy metabolism. The Journal of Clinical Endocrinology and Metabolism. 95: 4795-801. PMID 21051575 DOI: 10.1210/Jc.2010-1030  0.497
2010 Oury F, Yadav VK, Wang Y, Zhou B, Liu XS, Guo XE, Tecott LH, Schutz G, Means AR, Karsenty G. CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons. Genes & Development. 24: 2330-42. PMID 20952540 DOI: 10.1101/Gad.1977210  0.706
2010 Ducy P, Karsenty G. The two faces of serotonin in bone biology. The Journal of Cell Biology. 191: 7-13. PMID 20921133 DOI: 10.1083/Jcb.201006123  0.746
2010 Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Carta L, Ono RN, Sengle G, Arteaga-Solis E, Levasseur R, Ducy P, Sakai LY, Karsenty G, Ramirez F. Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation. The Journal of Cell Biology. 190: 1107-21. PMID 20855508 DOI: 10.1083/Jcb.201003089  0.798
2010 Oury F, Karsenty G. [Serotonin, two faces of a unique molecule in the regulation of bone mass]. MéDecine Sciences : M/S. 26: 713-8. PMID 20819707 DOI: 10.1051/Medsci/2010268-9713  0.521
2010 Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G. Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell. 142: 296-308. PMID 20655470 DOI: 10.1016/J.Cell.2010.06.003  0.823
2010 Ferron M, Wei J, Yoshizawa T, Ducy P, Karsenty G. An ELISA-based method to quantify osteocalcin carboxylation in mice. Biochemical and Biophysical Research Communications. 397: 691-6. PMID 20570657 DOI: 10.1016/J.Bbrc.2010.06.008  0.783
2010 Frost M, Andersen TE, Yadav V, Brixen K, Karsenty G, Kassem M. Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 673-5. PMID 20200960 DOI: 10.1002/Jbmr.44  0.679
2010 Shi Y, Oury F, Yadav VK, Wess J, Liu XS, Guo XE, Murshed M, Karsenty G. Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity. Cell Metabolism. 11: 231-8. PMID 20197056 DOI: 10.1016/J.Cmet.2010.01.005  0.836
2010 Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R, Vidal M, Karsenty G, Ducy P. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nature Medicine. 16: 308-12. PMID 20139991 DOI: 10.1038/Nm.2098  0.811
2010 Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice. The Journal of Clinical Investigation. 120: 357-68. PMID 20038793 DOI: 10.1172/Jci39901  0.441
2010 Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS. Parathyroid hormone regulates fetal-placental mineral homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 594-605. PMID 19968565 DOI: 10.1359/Jbmr.090825  0.408
2010 Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice (Journal of Clinical Investigation (2010) 120, 1 (357-368) (DOI:10.1172/JCI39901)) Journal of Clinical Investigation. 120: 932. DOI: 10.1172/Jci37672E1  0.397
2010 Frost M, Andersen T, Yadav V, Brixen K, Karsenty G, Kassem M. Patients with high bone mass phenotype due to Lrp5-T253i mutation have low plasma levels of serotonin Bone. 47: S121. DOI: 10.1016/J.Bone.2010.04.264  0.645
2010 Karsenty⁎ G, Marks P. Regulation of bone formation by gut-derived serotonin Bone. 47: S27-S28. DOI: 10.1016/J.Bone.2010.04.041  0.506
2009 Yadav VK, Karsenty G. Leptin-dependent co-regulation of bone and energy metabolism. Aging. 1: 954-6. PMID 20157577  0.673
2009 Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG, Chua SC, Wang Q, Kim JK, Kaestner KH, Karsenty G. An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion. Annals of the New York Academy of Sciences. 1173: E20-30. PMID 19751411 DOI: 10.1111/J.1749-6632.2009.05061.X  0.782
2009 Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 138: 976-89. PMID 19737523 DOI: 10.1016/J.Cell.2009.06.051  0.684
2009 Yoshizawa T, Hinoi E, Jung DY, Kajimura D, Ferron M, Seo J, Graff JM, Kim JK, Karsenty G. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. The Journal of Clinical Investigation. 119: 2807-17. PMID 19726872 DOI: 10.1172/Jci39366  0.793
2009 Ferron M, Karsenty G. The gutsy side of bone. Cell Metabolism. 10: 7-8. PMID 19583948 DOI: 10.1016/J.Cmet.2009.06.004  0.75
2009 Karsenty G, Kronenberg HM, Settembre C. Genetic control of bone formation. Annual Review of Cell and Developmental Biology. 25: 629-48. PMID 19575648 DOI: 10.1146/Annurev.Cellbio.042308.113308  0.702
2009 Oury F, Karsenty G. [Intestinal serotonin and regulation of bone mass]. MéDecine Sciences : M/S. 25: 445-6. PMID 19480820 DOI: 10.1051/Medsci/2009255445  0.479
2009 Confavreux CB, Levine RL, Karsenty G. A paradigm of integrative physiology, the crosstalk between bone and energy metabolisms. Molecular and Cellular Endocrinology. 310: 21-9. PMID 19376193 DOI: 10.1016/J.Mce.2009.04.004  0.506
2009 Kang S, Elf S, Dong S, Hitosugi T, Lythgoe K, Guo A, Ruan H, Lonial S, Khoury HJ, Williams IR, Lee BH, Roesel JL, Karsenty G, Hanauer A, Taunton J, et al. Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation. Molecular and Cellular Biology. 29: 2105-17. PMID 19223461 DOI: 10.1128/Mcb.00998-08  0.32
2009 Settembre C, Arteaga-Solis E, Ballabio A, Karsenty G. Self-eating in skeletal development: implications for lysosomal storage disorders. Autophagy. 5: 228-9. PMID 19029806 DOI: 10.4161/Auto.5.2.7390  0.635
2009 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, John Mann J, Hen R, Ducy P, Karsenty G. LDL-receptor related protein five controls bone formation by inhibiting serotonin synthesis in the duodenum Obstetrical and Gynecological Survey. 64: 240-242. DOI: 10.1097/01.Ogx.0000345723.85624.24  0.827
2009 Karsenty G. Cell Differentiation in the Skeleton Essentials of Stem Cell Biology. 223-226. DOI: 10.1016/B978-0-12-374729-7.00026-3  0.412
2009 Karsenty G, Elefteriou F. Neuronal Regulation of Bone Remodeling Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition. 56-60. DOI: 10.1002/9780470623992.Ch10  0.707
2008 Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Myers MG, Chua SC, Kim JK, Kaestner KH, Karsenty G. The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. The Journal of Cell Biology. 183: 1235-42. PMID 19103808 DOI: 10.1083/Jcb.200809113  0.738
2008 Shi Y, Yadav VK, Suda N, Liu XS, Guo XE, Myers MG, Karsenty G. Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 20529-33. PMID 19074282 DOI: 10.1073/Pnas.0808701106  0.765
2008 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell. 135: 825-37. PMID 19041748 DOI: 10.1016/J.Cell.2008.09.059  0.827
2008 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G. Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes & Development. 22: 2645-50. PMID 18832069 DOI: 10.1101/Gad.1711308  0.684
2008 Karsenty G. Transcriptional control of skeletogenesis. Annual Review of Genomics and Human Genetics. 9: 183-96. PMID 18767962 DOI: 10.1146/Annurev.Genom.9.081307.164437  0.454
2008 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, et al. The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease. Arthritis and Rheumatism. 58: 2764-75. PMID 18759297 DOI: 10.1002/Art.23805  0.643
2008 Singh MK, Elefteriou F, Karsenty G. Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule. Endocrinology. 149: 3933-41. PMID 18450969 DOI: 10.1210/En.2008-0109  0.75
2008 Lee NK, Karsenty G. Reciprocal regulation of bone and energy metabolism. Trends in Endocrinology and Metabolism: Tem. 19: 161-6. PMID 18407515 DOI: 10.1016/J.Tem.2008.02.006  0.471
2008 Ferron M, Hinoi E, Karsenty G, Ducy P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5266-70. PMID 18362359 DOI: 10.1073/Pnas.0711119105  0.812
2008 Takeda S, Karsenty G. Molecular bases of the sympathetic regulation of bone mass. Bone. 42: 837-40. PMID 18295563 DOI: 10.1016/J.Bone.2008.01.005  0.702
2008 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Awqati QA, Ballabio A, Karsenty G. Proteoglycan desulfation regulates endochondral ossification Matrix Biology. 27: 37. DOI: 10.1016/J.Matbio.2008.09.330  0.671
2007 Galler KM, Yasue A, Cavender AC, Bialek P, Karsenty G, D'Souza RN. A novel role for Twist-1 in pulp homeostasis. Journal of Dental Research. 86: 951-5. PMID 17890670 DOI: 10.1177/154405910708601007  0.791
2007 Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G. Endocrine regulation of energy metabolism by the skeleton. Cell. 130: 456-69. PMID 17693256 DOI: 10.1016/J.Cell.2007.05.047  0.824
2007 Zheng L, Baek HJ, Karsenty G, Justice MJ. Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner. The Journal of Cell Biology. 178: 121-8. PMID 17606870 DOI: 10.1083/Jcb.200703113  0.343
2007 Glass DA, Karsenty G. In vivo analysis of Wnt signaling in bone. Endocrinology. 148: 2630-4. PMID 17395705 DOI: 10.1210/En.2006-1372  0.759
2007 Hiramatsu K, Asaba Y, Takeshita S, Nimura Y, Tatsumi S, Katagiri N, Niida S, Nakajima T, Tanaka S, Ito M, Karsenty G, Ikeda K. Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis. Endocrinology. 148: 2708-15. PMID 17363454 DOI: 10.1210/En.2007-0215  0.518
2007 Kaartinen MT, Murshed M, Karsenty G, McKee MD. Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 375-86. PMID 17189522 DOI: 10.1369/Jhc.6A7087.2006  0.675
2007 Karsenty G. Genetic study of children's bone health and its therapeutic application Bone. 40: S14. DOI: 10.1016/J.Bone.2007.04.149  0.356
2006 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metabolism. 4: 441-51. PMID 17141628 DOI: 10.1016/J.Cmet.2006.10.010  0.748
2006 Karsenty G. Convergence between bone and energy homeostases: leptin regulation of bone mass. Cell Metabolism. 4: 341-8. PMID 17084709 DOI: 10.1016/J.Cmet.2006.10.008  0.515
2006 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G. Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes & Development. 20: 2937-42. PMID 17050674 DOI: 10.1101/Gad.1482906  0.808
2006 Fu L, Patel MS, Karsenty G. The circadian modulation of leptin-controlled bone formation. Progress in Brain Research. 153: 177-88. PMID 16876575 DOI: 10.1016/S0079-6123(06)53010-9  0.825
2006 Kamekura S, Kawasaki Y, Hoshi K, Shimoaka T, Chikuda H, Maruyama Z, Komori T, Sato S, Takeda S, Karsenty G, Nakamura K, Chung UI, Kawaguchi H. Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis and Rheumatism. 54: 2462-70. PMID 16868966 DOI: 10.1002/Art.22041  0.581
2006 Glass DA, Karsenty G. Canonical Wnt signaling in osteoblasts is required for osteoclast differentiation. Annals of the New York Academy of Sciences. 1068: 117-30. PMID 16831912 DOI: 10.1196/Annals.1346.015  0.761
2006 Glass DA, Karsenty G. Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway. Current Topics in Developmental Biology. 73: 43-84. PMID 16782455 DOI: 10.1016/S0070-2153(05)73002-7  0.755
2006 Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Fariñas I, Karsenty G, Grosschedl R. SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 125: 971-86. PMID 16751105 DOI: 10.1016/J.Cell.2006.05.012  0.533
2006 Winslow MM, Pan M, Starbuck M, Gallo EM, Deng L, Karsenty G, Crabtree GR. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Developmental Cell. 10: 771-82. PMID 16740479 DOI: 10.1016/J.Devcel.2006.04.006  0.556
2006 Ahn JD, Dubern B, Lubrano-Berthelier C, Clement K, Karsenty G. Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency. Endocrinology. 147: 3196-202. PMID 16614075 DOI: 10.1210/En.2006-0281  0.558
2006 Zaheer A, Murshed M, De Grand AM, Morgan TG, Karsenty G, Frangioni JV. Optical imaging of hydroxyapatite in the calcified vasculature of transgenic animals. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1132-6. PMID 16484598 DOI: 10.1161/01.Atv.0000210016.89991.2A  0.612
2006 Guo J, Chung UI, Yang D, Karsenty G, Bringhurst FR, Kronenberg HM. PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Developmental Biology. 292: 116-28. PMID 16476422 DOI: 10.1016/J.Ydbio.2005.12.044  0.439
2006 Wang X, Kua HY, Hu Y, Guo K, Zeng Q, Wu Q, Ng HH, Karsenty G, de Crombrugghe B, Yeh J, Li B. p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. The Journal of Cell Biology. 172: 115-25. PMID 16380437 DOI: 10.1083/Jcb.200507106  0.675
2005 Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 437: 417-21. PMID 16163358 DOI: 10.1038/Nature03928  0.64
2005 Fu L, Patel MS, Bradley A, Wagner EF, Karsenty G. The molecular clock mediates leptin-regulated bone formation. Cell. 122: 803-15. PMID 16143109 DOI: 10.1016/J.Cell.2005.06.028  0.833
2005 Clément K, Karsenty G. [Neural control of bone remodeling: crucial role of leptin]. Medecine Sciences : M/S. 21: 681-2. PMID 16115444 DOI: 10.1051/Medsci/2005218-9681  0.469
2005 Li L, Zhu J, Tu Q, Yamauchi M, Sodek J, Karsenty G, Tang J, Chen J. An in vivo model to study osteogenic gene regulation: targeting an avian retroviral receptor (TVA) to bone with the bone sialoprotein (BSP) promoter. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1403-13. PMID 16007338 DOI: 10.1359/Jbmr.050316  0.498
2005 Xiao G, Jiang D, Ge C, Zhao Z, Lai Y, Boules H, Phimphilai M, Yang X, Karsenty G, Franceschi RT. Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. The Journal of Biological Chemistry. 280: 30689-96. PMID 16000305 DOI: 10.1074/Jbc.M500750200  0.748
2005 Kondo H, Nifuji A, Takeda S, Ezura Y, Rittling SR, Denhardt DT, Nakashima K, Karsenty G, Noda M. Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. The Journal of Biological Chemistry. 280: 30192-200. PMID 15961387 DOI: 10.1074/Jbc.M504179200  0.684
2005 Dabovic B, Levasseur R, Zambuto L, Chen Y, Karsenty G, Rifkin DB. Osteopetrosis-like phenotype in latent TGF-β binding protein 3 deficient mice Bone. 37: 25-31. PMID 15878314 DOI: 10.1016/J.Bone.2005.02.021  0.527
2005 Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Developmental Cell. 8: 751-64. PMID 15866165 DOI: 10.1016/J.Devcel.2005.02.017  0.843
2005 Murshed M, Harmey D, Millán JL, McKee MD, Karsenty G. Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes & Development. 19: 1093-104. PMID 15833911 DOI: 10.1101/Gad.1276205  0.746
2005 Sakamoto A, Chen M, Nakamura T, Xie T, Karsenty G, Weinstein LS. Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone. The Journal of Biological Chemistry. 280: 21369-75. PMID 15797856 DOI: 10.1074/Jbc.M500346200  0.481
2005 Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 434: 514-20. PMID 15724149 DOI: 10.1038/Nature03398  0.863
2005 Karsenty G. New examples of a central control of bone mass Bonekey-Osteovision. 2: 34-35. DOI: 10.1138/20050185  0.331
2004 Chen YT, Levasseur R, Vaishnav S, Karsenty G, Bradley A. Bigenic Cre/loxP, puDeltatk conditional genetic ablation. Nucleic Acids Research. 32: e161. PMID 15561996 DOI: 10.1093/Nar/Gnh158  0.32
2004 Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell. 119: 555-66. PMID 15537544 DOI: 10.1016/J.Cell.2004.10.024  0.745
2004 Giacopelli F, Marciano R, Pistorio A, Catarsi P, Canini S, Karsenty G, Ravazzolo R. Polymorphisms in the osteopontin promoter affect its transcriptional activity. Physiological Genomics. 20: 87-96. PMID 15479859 DOI: 10.1152/Physiolgenomics.00138.2004  0.329
2004 Yang X, Karsenty G. ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. The Journal of Biological Chemistry. 279: 47109-14. PMID 15377660 DOI: 10.1074/Jbc.M410010200  0.724
2004 Cock TA, Back J, Elefteriou F, Karsenty G, Kastner P, Chan S, Auwerx J. Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen. Embo Reports. 5: 1007-12. PMID 15359271 DOI: 10.1038/Sj.Embor.7400254  0.745
2004 Murshed M, Schinke T, McKee MD, Karsenty G. Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins. The Journal of Cell Biology. 165: 625-30. PMID 15184399 DOI: 10.1083/Jcb.200402046  0.786
2004 Wang W, Wang YG, Reginato AM, Glotzer DJ, Fukai N, Plotkina S, Karsenty G, Olsen BR. Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice. Developmental Biology. 270: 364-81. PMID 15183720 DOI: 10.1016/J.Ydbio.2004.03.003  0.403
2004 Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 117: 387-98. PMID 15109498 DOI: 10.1016/S0092-8674(04)00344-7  0.843
2004 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A. Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 229: 826-34. PMID 15042706 DOI: 10.1002/Dvdy.20003  0.505
2004 Bialek P, Kern B, Yang X, Schrock M, Sosic D, Hong N, Wu H, Yu K, Ornitz DM, Olson EN, Justice MJ, Karsenty G. A twist code determines the onset of osteoblast differentiation. Developmental Cell. 6: 423-35. PMID 15030764 DOI: 10.1016/S1534-5807(04)00058-9  0.819
2004 Elefteriou F, Takeda S, Ebihara K, Magre J, Patano N, Kim CA, Ogawa Y, Liu X, Ware SM, Craigen WJ, Robert JJ, Vinson C, Nakao K, Capeau J, Karsenty G. Serum leptin level is a regulator of bone mass. Proceedings of the National Academy of Sciences of the United States of America. 101: 3258-63. PMID 14978271 DOI: 10.1073/Pnas.0308744101  0.812
2004 Dacquin R, Davey RA, Laplace C, Levasseur R, Morris HA, Goldring SR, Gebre-Medhin S, Galson DL, Zajac JD, Karsenty G. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. The Journal of Cell Biology. 164: 509-14. PMID 14970190 DOI: 10.1083/Jcb.200312135  0.543
2004 Cui Y, Huang L, Elefteriou F, Yang G, Shelton JM, Giles JE, Oz OK, Pourbahrami T, Lu CY, Richardson JA, Karsenty G, Li C. Essential role of STAT3 in body weight and glucose homeostasis. Molecular and Cellular Biology. 24: 258-69. PMID 14673160 DOI: 10.1128/Mcb.24.1.258-269.2004  0.669
2003 Glass DA, Patel MS, Karsenty G. A new insight into the formation of osteolytic lesions in multiple myeloma. The New England Journal of Medicine. 349: 2479-80. PMID 14695406 DOI: 10.1056/Nejmp038176  0.616
2003 Elefteriou F, Takeda S, Liu X, Armstrong D, Karsenty G. Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass. Endocrinology. 144: 3842-7. PMID 12933656 DOI: 10.1210/En.2003-0369  0.796
2003 Kim S, Koga T, Isobe M, Kern BE, Yokochi T, Chin YE, Karsenty G, Taniguchi T, Takayanagi H. Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation. Genes & Development. 17: 1979-91. PMID 12923053 DOI: 10.1101/Gad.1119303  0.552
2003 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R. Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. The Journal of Cell Biology. 162: 139-48. PMID 12835312 DOI: 10.1083/Jcb.200302066  0.647
2003 Levasseur R, Barrios R, Elefteriou F, Glass DA, Lieberman MW, Karsenty G. Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice. Endocrinology. 144: 2761-4. PMID 12810527 DOI: 10.1210/En.2002-0071  0.808
2003 Takeda S, Elefteriou F, Karsenty G. Common endocrine control of body weight, reproduction, and bone mass. Annual Review of Nutrition. 23: 403-11. PMID 12730321 DOI: 10.1146/Annurev.Nutr.23.011702.073312  0.814
2003 Tu Q, Pi M, Karsenty G, Simpson L, Liu S, Quarles LD. Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background. The Journal of Clinical Investigation. 111: 1029-37. PMID 12671052 DOI: 10.1172/Jci200317054  0.407
2003 Cui CB, Cooper LF, Yang X, Karsenty G, Aukhil I. Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ. Molecular and Cellular Biology. 23: 1004-13. PMID 12529404 DOI: 10.1128/Mcb.23.3.1004-1013.2003  0.709
2003 Stheneur C, Dumontier MF, Guedes C, Fulchignoni-Lataud MC, Tahiri K, Karsenty G, Corvol MT. Basic fibroblast growth factor as a selective inducer of matrix Gla protein gene expression in proliferative chondrocytes. The Biochemical Journal. 369: 63-70. PMID 12230429 DOI: 10.1042/Bj20020549  0.368
2003 El-Maadawy S, Kaartinen MT, Schinke T, Murshed M, Karsenty G, McKee MD. Cartilage Formation and Calcification in Arteries of Mice Lacking Matrix Gla Protein Connective Tissue Research. 44: 272-278. DOI: 10.1080/03008200390181762  0.727
2002 Chen S, Gu TT, Sreenath T, Kulkarni AB, Karsenty G, MacDougall M. Spatial expression of Cbfa1/Runx2 isoforms in teeth and characterization of binding sites in the DSPP gene. Connective Tissue Research. 43: 338-44. PMID 12489178 DOI: 10.1080/03008200290000691  0.323
2002 Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell. 111: 305-17. PMID 12419242 DOI: 10.1016/S0092-8674(02)01049-8  0.85
2002 Byers BA, Pavlath GK, Murphy TJ, Karsenty G, García AJ. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1931-44. PMID 12412799 DOI: 10.1359/Jbmr.2002.17.11.1931  0.466
2002 Speer MY, McKee MD, Guldberg RE, Liaw L, Yang HY, Tung E, Karsenty G, Giachelli CM. Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. The Journal of Experimental Medicine. 196: 1047-55. PMID 12391016 DOI: 10.1084/Jem.20020911  0.35
2002 Yang X, Karsenty G. Transcription factors in bone: developmental and pathological aspects. Trends in Molecular Medicine. 8: 340-5. PMID 12114114 DOI: 10.1016/S1471-4914(02)02340-7  0.758
2002 Dacquin R, Starbuck M, Schinke T, Karsenty G. Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 224: 245-51. PMID 12112477 DOI: 10.1002/Dvdy.10100  0.665
2002 Patel MS, Karsenty G. Regulation of bone formation and vision by LRP5. The New England Journal of Medicine. 346: 1572-4. PMID 12015398 DOI: 10.1056/Nejm200205163462011  0.487
2002 Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Developmental Cell. 2: 389-406. PMID 11970890 DOI: 10.1016/S1534-5807(02)00157-0  0.303
2002 Kato M, Patel MS, Levasseur R, Lobov I, Chang BH, Glass DA, Hartmann C, Li L, Hwang TH, Brayton CF, Lang RA, Karsenty G, Chan L. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. The Journal of Cell Biology. 157: 303-14. PMID 11956231 DOI: 10.1083/Jcb.200201089  0.739
2002 O’Brien CA, Kern B, Gubrij I, Karsenty G, Manolagas SC. Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells. Bone. 30: 453-462. PMID 11882458 DOI: 10.1016/S8756-3282(01)00692-5  0.424
2002 Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA. p53 mutant mice that display early ageing-associated phenotypes. Nature. 415: 45-53. PMID 11780111 DOI: 10.1038/415045A  0.302
2001 Amling M, Pogoda P, Beil FT, Schilling AF, Holzmann T, Priemel M, Blicharski D, Català-Lehnen P, Rueger JM, Ducy P, Karsenty G. Central control of bone mass: brainstorming of the skeleton. Advances in Experimental Medicine and Biology. 496: 85-94. PMID 11783628 DOI: 10.1007/978-1-4615-0651-5_9  0.769
2001 Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM. Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers Circulation Research. 89: 1147-1154. PMID 11739279 DOI: 10.1161/Hh2401.101070  0.599
2001 Wagner EF, Karsenty G. Genetic control of skeletal development. Current Opinion in Genetics & Development. 11: 527-32. PMID 11532394 DOI: 10.1016/S0959-437X(00)00228-8  0.442
2001 Karsenty G. Minireview: transcriptional control of osteoblast differentiation. Endocrinology. 142: 2731-2733. PMID 11415989 DOI: 10.1210/Endo.142.7.8306  0.463
2001 Takeda S, Karsenty G. Central control of bone formation. Journal of Bone and Mineral Metabolism. 19: 195-8. PMID 11368306 DOI: 10.1007/S007740170042  0.689
2001 Karsenty G. When developmental biology meets human pathology Proceedings of the National Academy of Sciences of the United States of America. 98: 5385-5386. PMID 11344281 DOI: 10.1073/Pnas.121162198  0.333
2001 Alliston T, Choy L, Ducy P, Karsenty G, Derynck R. TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. The Embo Journal. 20: 2254-72. PMID 11331591 DOI: 10.1093/Emboj/20.9.2254  0.682
2001 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes & Development. 15: 467-81. PMID 11230154 DOI: 10.1101/Gad.845101  0.791
2001 Karsenty G. Chondrogenesis just ain’t what it used to be Journal of Clinical Investigation. 107: 405-407. PMID 11181639 DOI: 10.1172/Jci12294  0.475
2001 Kern B, Shen J, Starbuck M, Karsenty G. Cbfa1 Contributes to the Osteoblast-specific Expression of type I collagen Genes Journal of Biological Chemistry. 276: 7101-7107. PMID 11106645 DOI: 10.1074/Jbc.M006215200  0.316
2001 Karsenty G. The central regulation of bone remodeling. Trends in Endocrinology and Metabolism: Tem. 11: 437-9. PMID 11091123 DOI: 10.1016/S1043-2760(00)00322-2  0.426
2001 Amling M, Takeda S, Karsenty G. A neuro (endo)crine regulation of bone remodeling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 970-5. PMID 11056473 DOI: 10.1002/1521-1878(200011)22:11<970::Aid-Bies3>3.0.Co;2-L  0.755
2000 Karsenty G. Role of Cbfa1 in osteoblast differentiation and function. Seminars in Cell & Developmental Biology. 11: 343-346. PMID 11105898 DOI: 10.1006/Scdb.2000.0188  0.482
2000 Schinke T, Karsenty G. Vascular calcification—a passive process in need of inhibitors Nephrology Dialysis Transplantation. 15: 1272-1274. PMID 10978374 DOI: 10.1093/Ndt/15.9.1272  0.478
2000 Karsenty G. How many factors are required to remodel bone? Nature Medicine. 6: 970-1. PMID 10973309 DOI: 10.1038/79655  0.488
2000 Ducy P, Schinke T, Karsenty G. The Osteoblast: A Sophisticated Fibroblast under Central Surveillance Science. 289: 1501-1504. PMID 10968779 DOI: 10.1126/Science.289.5484.1501  0.813
2000 Günther T, Chen ZF, Kim J, Priemel M, Rueger JM, Amling M, Moseley JM, Martin TJ, Anderson DJ, Karsenty G. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature. 406: 199-203. PMID 10910362 DOI: 10.1038/35018111  0.523
2000 Abidari JM, Gonzales ET, Inoue K, Lupski JR, Karsenty G, Katsanis N. Identification of novel genes expressed during metanephric induction through single-cell library screening. Kidney International. 57: 2221-8. PMID 10844592 DOI: 10.1046/J.1523-1755.2000.00185.X  0.318
2000 Ducy P, Karsenty G. The family of bone morphogenetic proteins Kidney International. 57: 2207-2214. PMID 10844590 DOI: 10.1046/J.1523-1755.2000.00081.X  0.739
2000 Karsenty G. Bone formation and factors affecting this process. Matrix Biology. 19: 85-89. PMID 10842091 DOI: 10.1016/S0945-053X(00)00053-6  0.457
2000 Xiao G, Jiang D, Thomas P, Benson MD, Guan K, Karsenty G, Franceschi RT. MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. The Journal of Biological Chemistry. 275: 4453-9. PMID 10660618 DOI: 10.1074/Jbc.275.6.4453  0.437
2000 Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell. 100: 197-207. PMID 10660043 DOI: 10.1016/S0092-8674(00)81558-5  0.841
2000 McLarren KW, Lo R, Grbavec D, Thirunavukkarasu K, Karsenty G, Stifani S. The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1. The Journal of Biological Chemistry. 275: 530-8. PMID 10617648 DOI: 10.1074/Jbc.275.1.530  0.328
1999 Karsenty G. The Genetic Transformation of Bone Biology Genes & Development. 13: 3037-3051. PMID 10601030 DOI: 10.1101/Gad.13.23.3037  0.501
1999 Zhou G, Chen Y, Zhou L, Thirunavukkarasu K, Hecht J, Chitayat D, Gelb BD, Pirinen S, Berry SA, Greenberg CR, Karsenty G, Lee B. CBFA1 mutation analysis and functional correlation with phenotypic variability in cleidocranial dysplasia. Human Molecular Genetics. 8: 2311-6. PMID 10545612 DOI: 10.1093/Hmg/8.12.2311  0.461
1999 Schinke T, Karsenty G. Characterization of Osf1, an Osteoblast-specific Transcription Factor Binding to a Critical cis-acting Element in the MouseOsteocalcin Promoters Journal of Biological Chemistry. 274: 30182-30189. PMID 10514508 DOI: 10.1074/Jbc.274.42.30182  0.61
1999 Tintut Y, Parhami F, Le V, Karsenty G, Demer LL. Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. Journal of Biological Chemistry. 274: 28875-28879. PMID 10506130 DOI: 10.1074/Jbc.274.41.28875  0.415
1999 Karsenty G, Ducy P, Starbuck M, Priemel M, Shen J, Geoffroy V, Amling M. Cbfa1 as a regulator of osteoblast differentiation and function. Bone. 25: 107-108. PMID 10423032 DOI: 10.1016/S8756-3282(99)00111-8  0.741
1999 Jiang H, Sodek J, Karsenty G, Thomas H, Ranly D, Chen J. Expression of core binding factor Osf2/Cbfa-1 and bone sialoprotein in tooth development. Mechanisms of Development. 81: 169-73. PMID 10330494 DOI: 10.1016/S0925-4773(98)00232-9  0.395
1999 Ducy P, Starbuck M, Priemel M, Shen J, Pinero G, Geoffroy V, Amling M, Karsenty G. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes & Development. 13: 1025-36. PMID 10215629 DOI: 10.1101/Gad.13.8.1025  0.811
1999 Schinke T, McKee MD, Karsenty G. Extracellular matrix calcification: where is the action? Nature Genetics. 21: 150-1. PMID 9988260 DOI: 10.1038/5928  0.609
1999 Ducy P, Karsenty G. Transcriptional Control of Osteoblast Differentiation The Endocrinologist. 9: 32-35. DOI: 10.1097/00019616-199901000-00007  0.672
1998 Xiao G, Wang D, Benson MD, Karsenty G, Franceschi RT. Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. The Journal of Biological Chemistry. 273: 32988-94. PMID 9830051 DOI: 10.1074/Jbc.273.49.32988  0.413
1998 Ducy P, Karsenty G. Genetic control of cell differentiation in the skeleton. Current Opinion in Cell Biology. 10: 614-619. PMID 9818172 DOI: 10.1016/S0955-0674(98)80037-9  0.68
1998 Corral DA, Amling M, Priemel M, Loyer E, Fuchs S, Ducy P, Baron R, Karsenty G. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 13835-40. PMID 9811887 DOI: 10.1073/Pnas.95.23.13835  0.796
1998 Frendo JL, Xiao G, Fuchs S, Franceschi RT, Karsenty G, Ducy P. Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo. The Journal of Biological Chemistry. 273: 30509-16. PMID 9804819 DOI: 10.1074/Jbc.273.46.30509  0.699
1998 Boskey AL, Gadaleta S, Gundberg C, Doty SB, Ducy P, Karsenty G. Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Bone. 23: 187-96. PMID 9737340 DOI: 10.1016/S8756-3282(98)00092-1  0.744
1998 Owen MJ, Karsenty G. New developments in bone formation. Current Opinion in Nephrology and Hypertension. 7: 363-6. PMID 9690033 DOI: 10.1097/00041552-199807000-00003  0.428
1998 Karsenty G. Transcriptional regulation of osteoblast differentiation during development. Frontiers in Bioscience. 3. PMID 9682035 DOI: 10.2741/A326  0.504
1998 Katagiri T, Boorla S, Frendo J, Hogan BLM, Karsenty G. Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice. Developmental Genetics. 22: 340-348. PMID 9664686 DOI: 10.1002/(Sici)1520-6408(1998)22:4<340::Aid-Dvg4>3.0.Co;2-6  0.413
1998 Chen D, Ji X, Harris MA, Feng JQ, Karsenty G, Celeste AJ, Rosen V, Mundy GR, Harris SE. Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. Journal of Cell Biology. 142: 295-305. PMID 9660882 DOI: 10.1083/Jcb.142.1.295  0.491
1998 Schinke T, McKee MD, Kiviranta R, Karsenty G. Trends in Molecular Medicine: Molecular determinants of arterial calcification Annals of Medicine. 30: 538-541. DOI: 10.3109/07853899709002601  0.56
1997 Lee B, Thirunavukkarasu K, Zhou L, Pastore L, Baldini A, Hecht J, Geoffroy V, Ducy P, Karsenty G. Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nature Genetics. 16: 307-10. PMID 9207800 DOI: 10.1038/Ng0797-307  0.71
1997 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89: 747-54. PMID 9182762 DOI: 10.1016/S0092-8674(00)80257-3  0.731
1997 Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 386: 78-81. PMID 9052783 DOI: 10.1038/386078A0  0.765
1997 Zhang R, Ducy P, Karsenty G. 1,25-Dihydroxyvitamin D3 Inhibits Osteocalcin Expression in Mouse through an Indirect Mechanism Journal of Biological Chemistry. 272: 110-116. PMID 8995235 DOI: 10.1074/Jbc.272.1.110  0.665
1996 Ducy P, Geoffroy V, Karsenty G. Study of Osteoblast-Specific Expression of One Mouse Osteocalcin Gene: Characterization of the Factor Binding to OSE2 Connective Tissue Research. 35: 7-14. PMID 9084638 DOI: 10.3109/03008209609029169  0.665
1996 Bronckers AL, Goei W, Luo G, Karsenty G, D'Souza RN, Lyaruu DM, Burger EH. DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end labeling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 1281-91. PMID 8864903 DOI: 10.1002/Jbmr.5650110913  0.718
1996 Bronckers AL, Lyaruu DM, Goei W, Litz M, Luo G, Karsenty G, Wöltgens JH, D'Souza RN. Nuclear DNA fragmentation during postnatal tooth development of mouse and hamster and during dentin repair in the rat. European Journal of Oral Sciences. 104: 102-11. PMID 8804897 DOI: 10.1111/J.1600-0722.1996.Tb00053.X  0.599
1996 Hofmann C, Luo G, Balling R, Karsenty G. Analysis of limb patterning in BMP-7-deficient mice. Developmental Genetics. 19: 43-50. PMID 8792608 DOI: 10.1002/(Sici)1520-6408(1996)19:1<43::Aid-Dvg5>3.0.Co;2-0  0.7
1996 Galéra P, Park R, Ducy P, Mattéi M, Karsenty G. c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis. Journal of Biological Chemistry. 271: 21331-21339. PMID 8702912 DOI: 10.1074/Jbc.271.35.21331  0.658
1996 Karsenty G, Luo G, Hofmann C, Bradley A. BMP 7 Is Required for Nephrogenesis, Eye Development, and Skeletal Patterninga Annals of the New York Academy of Sciences. 785: 98-107. PMID 8702187 DOI: 10.1111/J.1749-6632.1996.Tb56247.X  0.672
1996 Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G. Increased bone formation in osteocalcin-deficient mice. Nature. 382: 448-52. PMID 8684484 DOI: 10.1038/382448A0  0.761
1995 Geoffroy V, Ducy P, Karsenty G. A PEBP2/AML-1-related Factor Increases Osteocalcin Promoter Activity through Its Binding to an Osteoblast-specific cis-Acting Element Journal of Biological Chemistry. 270: 30973-30979. PMID 8537354 DOI: 10.1074/Jbc.270.52.30973  0.666
1995 Ducy P, Karsenty G. Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene. Molecular and Cellular Biology. 15: 1858-1869. PMID 7891679 DOI: 10.1128/Mcb.15.4.1858  0.69
1995 Desbois C, Karsenty G. Osteocalcin cluster: Implications for functional studies Journal of Cellular Biochemistry. 57: 379-383. PMID 7768973 DOI: 10.1002/Jcb.240570302  0.511
1995 Luo G, D'Souza R, Hogue D, Karsenty G. The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development Journal of Bone and Mineral Research. 10: 325-334. PMID 7754814 DOI: 10.1002/Jbmr.5650100221  0.658
1995 Karsenty G, Park R. Regulation of Type I Collagen Genes Expression International Reviews of Immunology. 12: 177-185. PMID 7650420 DOI: 10.3109/08830189509056711  0.421
1995 Luo G, Hofmann C, Bronckers AL, Sohocki M, Bradley A, Karsenty G. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes & Development. 9: 2808-20. PMID 7590255 DOI: 10.1101/Gad.9.22.2808  0.709
1994 Galéra P, Musso M, Ducy P, Karsenty G. c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin. Proceedings of the National Academy of Sciences of the United States of America. 91: 9372-9376. PMID 7937772 DOI: 10.1073/Pnas.91.20.9372  0.679
1994 Galéra P, Desbois C, Ducy P, Karsenty G. La régulation de l'expression des gènes du collagène de type I : implication pour l'étude de la sclérodermie MéDecine/Sciences. 10: 1253. DOI: 10.4267/10608/2564  0.602
1994 Galéra P, Musso M, Park R, Karsenty G. c-Krox: A new transcription regulator of type I collagen genes preferentially expressed in skin Matrix Biology. 14: 368. DOI: 10.1016/0945-053X(94)90067-1  0.302
1991 Crombrugghe Bd, Vuorio T, Karsenty G, Maity S, Rutheshouser EC, Goldberg H. Transcriptional control mechanisms for the expression of type I collagen genes. Annals of the Rheumatic Diseases. 50: 872-876. PMID 1750800 DOI: 10.1136/Ard.50.Suppl_4.872  0.323
1990 De Crombrugghe B, Karsenty G, Maity S, Vuorio T, Rossi P, Ruteshouser EC, McKinney SH, Lozano G. Transcriptional mechanisms controlling types I and III collagen genes. Annals of the New York Academy of Sciences. 580: 88-96. PMID 2337308 DOI: 10.1111/J.1749-6632.1990.Tb17921.X  0.631
1988 Maity SN, Golumbek PT, Karsenty G, de Crombrugghe B. Selective activation of transcription by a novel CCAAT binding factor. Science (New York, N.Y.). 241: 582-5. PMID 3399893 DOI: 10.1126/Science.3399893  0.544
1988 Rossi P, Karsenty G, Roberts AB, Roche NS, Sporn MB, de Crombrugghe B. A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta. Cell. 52: 405-14. PMID 2830985 DOI: 10.1016/S0092-8674(88)80033-3  0.587
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