Sahebarao P. Mahadik - Publications

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Neurochemistry of Mental Illness

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Jindal RD, Pillai AK, Mahadik SP, Eklund K, Montrose DM, Keshavan MS. Decreased BDNF in patients with antipsychotic naïve first episode schizophrenia. Schizophrenia Research. 119: 47-51. PMID 20096541 DOI: 10.1016/j.schres.2009.12.035  0.325
2010 Kale A, Naphade N, Sapkale S, Kamaraju M, Pillai A, Joshi S, Mahadik S. Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: Implications for altered one-carbon metabolism Psychiatry Research. 175: 47-53. PMID 19969375 DOI: 10.1016/j.psychres.2009.01.013  0.384
2010 Pillai A, Kale A, Joshi S, Naphade N, Raju MS, Nasrallah H, Mahadik SP. Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 535-9. PMID 19941699 DOI: 10.1017/S1461145709991015  0.364
2009 Kale A, Joshi S, Pillai A, Naphade N, Raju M, Nasrallah H, Mahadik SP. Reduced cerebrospinal fluid and plasma nerve growth factor in drug-naïve psychotic patients. Schizophrenia Research. 115: 209-14. PMID 19713082 DOI: 10.1016/J.Schres.2009.07.022  0.431
2008 Terry AV, Warner SE, Vandenhuerk L, Pillai A, Mahadik SP, Zhang G, Bartlett MG. Negative effects of chronic oral chlorpromazine and olanzapine treatment on the performance of tasks designed to assess spatial learning and working memory in rats. Neuroscience. 156: 1005-16. PMID 18801413 DOI: 10.1016/J.Neuroscience.2008.08.030  0.415
2008 Pillai A, Veeranan-Karmegam R, Dhandapani KM, Mahadik SP. Cystamine prevents haloperidol-induced decrease of BDNF/TrkB signaling in mouse frontal cortex. Journal of Neurochemistry. 107: 941-51. PMID 18786174 DOI: 10.1111/J.1471-4159.2008.05665.X  0.397
2008 Pillai A, Mahadik SP. Increased truncated TrkB receptor expression and decreased BDNF/TrkB signaling in the frontal cortex of reeler mouse model of schizophrenia. Schizophrenia Research. 100: 325-33. PMID 18187310 DOI: 10.1016/J.Schres.2007.11.030  0.359
2008 Kale A, Joshi S, Naphade N, Sapkale S, Raju MS, Pillai A, Nasrallah H, Mahadik SP. Opposite changes in predominantly docosahexaenoic acid (DHA) in cerebrospinal fluid and red blood cells from never-medicated first-episode psychotic patients. Schizophrenia Research. 98: 295-301. PMID 17997280 DOI: 10.1016/J.Schres.2007.09.036  0.435
2008 Mehendale S, Kilari A, Dangat K, Taralekar V, Mahadik S, Joshi S. Fatty acids, antioxidants, and oxidative stress in pre-eclampsia International Journal of Gynecology and Obstetrics. 100: 234-238. PMID 17977540 DOI: 10.1016/j.ijgo.2007.08.011  0.317
2008 Pillai A, Dhandapani KM, Pillai BA, Terry AV, Mahadik SP. Erythropoietin prevents haloperidol treatment-induced neuronal apoptosis through regulation of BDNF. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1942-51. PMID 17805306 DOI: 10.1038/Sj.Npp.1301566  0.46
2007 Terry AV, Gearhart DA, Warner S, Hohnadel EJ, Middlemore ML, Zhang G, Bartlett MG, Mahadik SP. Protracted effects of chronic oral haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial reference learning in rats. Neuroscience. 150: 413-24. PMID 17942237 DOI: 10.1016/J.Neuroscience.2007.09.014  0.493
2007 Rao SS, Kale AA, Joshi SR, Mahadik SP. Sensitivity of fetus and pups to excess levels of maternal intakes of alpha linolenic acid at marginal protein levels in Wistar rats. Reproductive Toxicology (Elmsford, N.Y.). 24: 333-42. PMID 17825521 DOI: 10.1016/j.reprotox.2007.07.007  0.313
2007 Buckley PF, Mahadik S, Pillai A, Terry A. Neurotrophins and schizophrenia Schizophrenia Research. 94: 1-11. PMID 17524622 DOI: 10.1016/J.Schres.2007.01.025  0.392
2007 Terry AV, Gearhart DA, Warner SE, Zhang G, Bartlett MG, Middlemore ML, Beck WD, Mahadik SP, Waller JL. Oral haloperidol or risperidone treatment in rats: temporal effects on nerve growth factor receptors, cholinergic neurons, and memory performance. Neuroscience. 146: 1316-32. PMID 17434684 DOI: 10.1016/J.Neuroscience.2007.03.003  0.425
2007 Buckley PF, Pillai A, Evans D, Stirewalt E, Mahadik S. Brain derived neurotropic factor in first-episode psychosis Schizophrenia Research. 91: 1-5. PMID 17306505 DOI: 10.1016/J.Schres.2006.12.026  0.453
2007 Terry AV, Mahadik SP. Time-dependent cognitive deficits associated with first and second generation antipsychotics: cholinergic dysregulation as a potential mechanism. The Journal of Pharmacology and Experimental Therapeutics. 320: 961-8. PMID 16966470 DOI: 10.1124/Jpet.106.106047  0.423
2007 Pillai A, Parikh V, Terry AV, Mahadik SP. Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. Journal of Psychiatric Research. 41: 372-86. PMID 16564057 DOI: 10.1016/J.Jpsychires.2006.01.011  0.64
2006 Pillai A, Mahadik SP. Differential effects of haloperidol and olanzapine on the expression of erythropoietin and its receptor in rat hippocampus and striatum. Journal of Neurochemistry. 98: 1411-22. PMID 16923156 DOI: 10.1111/j.1471-4159.2006.04057.x  0.42
2006 Pillai A, Mahadik SP. Differential effects of haloperidol and olanzapine on levels of vascular endothelial growth factor and angiogenesis in rat hippocampus. Schizophrenia Research. 87: 48-59. PMID 16859894 DOI: 10.1016/j.schres.2006.06.017  0.364
2006 Mahadik SP, Pillai A, Joshi S, Foster A. Prevention of oxidative stress-mediated neuropathology and improved clinical outcome by adjunctive use of a combination of antioxidants and omega-3 fatty acids in schizophrenia. International Review of Psychiatry (Abingdon, England). 18: 119-31. PMID 16777666 DOI: 10.1080/09540260600581993  0.404
2006 Terry AV, Parikh V, Gearhart DA, Pillai A, Hohnadel E, Warner S, Nasrallah HA, Mahadik SP. Time-dependent effects of haloperidol and ziprasidone on nerve growth factor, cholinergic neurons, and spatial learning in rats. The Journal of Pharmacology and Experimental Therapeutics. 318: 709-24. PMID 16702442 DOI: 10.1124/Jpet.105.099218  0.646
2006 Rao S, Joshi S, Kale A, Hegde M, Mahadik S. Maternal folic acid supplementation to dams on marginal protein level alters brain fatty acid levels of their adult offspring Metabolism: Clinical and Experimental. 55: 628-634. PMID 16631439 DOI: 10.1016/j.metabol.2005.12.008  0.303
2006 Terry AV, Gearhart DA, Mahadik SP, Warsi S, Waller JL. Chronic treatment with first or second generation antipsychotics in rodents: effects on high affinity nicotinic and muscarinic acetylcholine receptors in the brain. Neuroscience. 140: 1277-87. PMID 16626873 DOI: 10.1016/J.Neuroscience.2006.03.011  0.402
2006 Pillai A, Terry AV, Mahadik SP. Differential effects of long-term treatment with typical and atypical antipsychotics on NGF and BDNF levels in rat striatum and hippocampus. Schizophrenia Research. 82: 95-106. PMID 16442781 DOI: 10.1016/J.Schres.2005.11.021  0.462
2005 Terry AV, Gearhart DA, Mahadik SP, Warsi S, Davis LW, Waller JL. Chronic exposure to typical or atypical antipsychotics in rodents: temporal effects on central alpha7 nicotinic acetylcholine receptors. Neuroscience. 136: 519-29. PMID 16216423 DOI: 10.1016/J.Neuroscience.2005.08.006  0.38
2005 Skinner AO, Mahadik SP, Garver DL. Thiobarbituric acid reactive substances in the cerebrospinal fluid in schizophrenia. Schizophrenia Research. 76: 83-7. PMID 15927801 DOI: 10.1016/j.schres.2004.10.010  0.44
2004 Parikh V, Khan MM, Terry A, Mahadik SP. Differential effects of typical and atypical antipsychotics on nerve growth factor and choline acetyltransferase expression in the cortex and nucleus basalis of rats. Journal of Psychiatric Research. 38: 521-9. PMID 15380403 DOI: 10.1016/J.Jpsychires.2004.03.008  0.656
2004 Parikh V, Khan MM, Mahadik SP. Olanzapine counteracts reduction of brain-derived neurotrophic factor and TrkB receptors in rat hippocampus produced by haloperidol. Neuroscience Letters. 356: 135-9. PMID 14746882 DOI: 10.1016/j.neulet.2003.10.079  0.638
2004 Parikh V, Terry AV, Khan MM, Mahadik SP. Modulation of nerve growth factor and choline acetyltransferase expression in rat hippocampus after chronic exposure to haloperidol, risperidone, and olanzapine. Psychopharmacology. 172: 365-74. PMID 14647958 DOI: 10.1007/S00213-003-1669-6  0.639
2003 Ranjekar PK, Hinge A, Hegde MV, Ghate M, Kale A, Sitasawad S, Wagh UV, Debsikdar VB, Mahadik SP. Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients. Psychiatry Research. 121: 109-22. PMID 14656446 DOI: 10.1016/S0165-1781(03)00220-8  0.419
2003 Evans DR, Parikh VV, Khan MM, Coussons C, Buckley PF, Mahadik SP. Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatment. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 69: 393-9. PMID 14623492 DOI: 10.1016/j.plefa.2003.08.010  0.596
2003 Khan MM, Parikh VV, Mahadik SP. Antipsychotic drugs differentially modulate apolipoprotein D in rat brain. Journal of Neurochemistry. 86: 1089-100. PMID 12911617 DOI: 10.1046/J.1471-4159.2003.01866.X  0.647
2003 Arvindakshan M, Ghate M, Ranjekar PK, Evans DR, Mahadik SP. Supplementation with a combination of omega-3 fatty acids and antioxidants (vitamins E and C) improves the outcome of schizophrenia. Schizophrenia Research. 62: 195-204. PMID 12837515 DOI: 10.1016/S0920-9964(02)00284-0  0.412
2003 Mahadik SP, Evans DR. Is schizophrenia a metabolic brain disorder? Membrane phospholipid dysregulation and its therapeutic implications. The Psychiatric Clinics of North America. 26: 85-102. PMID 12683261 DOI: 10.1016/S0193-953X(02)00033-3  0.405
2003 Parikh V, Evans DR, Khan MM, Mahadik SP. Nerve growth factor in never-medicated first-episode psychotic and medicated chronic schizophrenic patients: possible implications for treatment outcome. Schizophrenia Research. 60: 117-23. PMID 12591576 DOI: 10.1016/S0920-9964(02)00434-6  0.649
2003 Terry AV, Hill WD, Parikh V, Waller JL, Evans DR, Mahadik SP. Differential effects of haloperidol, risperidone, and clozapine exposure on cholinergic markers and spatial learning performance in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 300-9. PMID 12589383 DOI: 10.1038/Sj.Npp.1300039  0.649
2003 Arvindakshan M, Sitasawad S, Debsikdar V, Ghate M, Evans D, Horrobin DF, Bennett C, Ranjekar PK, Mahadik SP. Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients. Biological Psychiatry. 53: 56-64. PMID 12513945 DOI: 10.1016/S0006-3223(02)01443-9  0.396
2003 Parikh V, Khan MM, Mahadik SP. Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. Journal of Psychiatric Research. 37: 43-51. PMID 12482469 DOI: 10.1016/S0022-3956(02)00048-1  0.661
2003 Terry A, Parikh V, Mahadik S. Differential effects of haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial learning in rats Schizophrenia Research. 60: 117. DOI: 10.1016/S0920-9964(03)80874-5  0.58
2003 Parikh V, Terry A, Mahadik S. Modulation of brain nerve growth factor and choline-acetyltransferase expression by chronic exposure to haloperidol, risperidone, or olanzapine in rats Schizophrenia Research. 60: 113-114. DOI: 10.1016/S0920-9964(03)80864-2  0.601
2003 Buckley PF, Mahadik S, Evans D, Stirewalt E. Schizophrenia: Causes, course, and neurodevelopment Current Psychosis & Therapeutics Reports. 1: 41-49. DOI: 10.1007/Bf02629438  0.377
2002 Terry AV, Hill WD, Parikh V, Evans DR, Waller JL, Mahadik SP. Differential effects of chronic haloperidol and olanzapine exposure on brain cholinergic markers and spatial learning in rats. Psychopharmacology. 164: 360-8. PMID 12457265 DOI: 10.1007/S00213-002-1230-Z  0.639
2002 Mahadik SP, Khan MM, Evans DR, Parikh VV. Elevated plasma level of apolipoprotein D in schizophrenia and its treatment and outcome. Schizophrenia Research. 58: 55-62. PMID 12363390 DOI: 10.1016/S0920-9964(01)00378-4  0.67
2002 Khan MM, Evans DR, Gunna V, Scheffer RE, Parikh VV, Mahadik SP. Reduced erythrocyte membrane essential fatty acids and increased lipid peroxides in schizophrenia at the never-medicated first-episode of psychosis and after years of treatment with antipsychotics. Schizophrenia Research. 58: 1-10. PMID 12363384 DOI: 10.1016/S0920-9964(01)00334-6  0.663
2002 Wakade CG, Mahadik SP, Waller JL, Chiu FC. Atypical neuroleptics stimulate neurogenesis in adult rat brain. Journal of Neuroscience Research. 69: 72-9. PMID 12111817 DOI: 10.1002/jnr.10281  0.389
2001 Mahadik SP, Evans D, Lal H. Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 25: 463-93. PMID 11370992 DOI: 10.1016/S0278-5846(00)00181-0  0.412
2000 Yao JK, Reddy RD, Pettegrew JW, Kammen DPv, Horrobin DF, Mahadik SP. 190. Membrane deficits in schizophrenia Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00453-4  0.375
2000 Mahadik SP, Terry A, Hill WD, Evans DR, Rausch JL. 68. Neuroprotective actions of olanzapine in rat: mechanism Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00330-9  0.418
2000 Mahadik S, Terry A, Hill W, Evans D, Rausch J. 67. Neuroprotective actions of olanzapine in rat: cholinergic function Biological Psychiatry. 47: S20-S21. DOI: 10.1016/S0006-3223(00)00329-2  0.305
1998 Mahadik SP, Mukherjee S, Scheffer R, Correnti EE, Mahadik JS. Elevated plasma lipid peroxides at the onset of nonaffective psychosis. Biological Psychiatry. 43: 674-9. PMID 9583001 DOI: 10.1016/S0006-3223(97)00282-5  0.44
1996 Mukerjee S, Mahadik SP, Scheffer R, Correnti EE, Kelkar H. Impaired antioxidant defense at the onset of psychosis. Schizophrenia Research. 19: 19-26. PMID 9147492 DOI: 10.1016/0920-9964(95)00048-8  0.393
1996 Mahadik SP, Mukherjee S. Free radical pathology and antioxidant defense in schizophrenia: a review. Schizophrenia Research. 19: 1-17. PMID 9147491 DOI: 10.1016/0920-9964(95)00049-6  0.433
1996 Mahadik SP, Mukherjee S. Cultured skin fibroblasts as a cell model for investigating schizophrenia. Journal of Psychiatric Research. 30: 421-39. PMID 9023786 DOI: 10.1016/S0022-3956(96)00025-8  0.359
1996 Mahadik SP, Scheffer RE. Oxidative injury and potential use of antioxidants in schizophrenia. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 55: 45-54. PMID 8888122  0.338
1996 Mahadik SP, Mukherjee S, Horrobin DF, Jenkins K, Correnti EE, Scheffer RE. Plasma membrane phospholipid fatty acid composition of cultured skin fibroblasts from schizophrenic patients: comparison with bipolar patients and normal subjects. Psychiatry Research. 63: 133-42. PMID 8878309 DOI: 10.1016/0165-1781(96)02899-5  0.357
1996 Evans DR, Puczkowski PY, Brandsma MJ, Mahadik JS, Mahadik SP. Elevated plasma lipid peroxides in schizophrenic patients without dementia Biological Psychiatry. 39: 588. DOI: 10.1016/0006-3223(96)84247-8  0.32
1996 Mahadik SP, Shendarkar NS, Scheffer RE, Mukherjee S, Correnti EE. Defective utilization of precursor essential fatty acids in schizophrenia Biological Psychiatry. 39: 588. DOI: 10.1016/0006-3223(96)84246-6  0.349
1995 Mahadik SP, Mukherjee S. Monosialoganglioside cotreatment prevents haloperidol treatment-associated loss of cholinergic enzymes in rat brain. Biological Psychiatry. 38: 246-54. PMID 8547447 DOI: 10.1016/0006-3223(94)00304-L  0.369
1995 Mukherjee S, Mahadik SP. Role of oxidative injury in the pathogenesis of schizophrenia Schizophrenia Research. 15: 195. DOI: 10.1016/0920-9964(95)95602-6  0.334
1995 Mahadik SP, Mukherjee S, Correnti EE, Scheffer R. Elevated levels of lipid peroxidation products in plasma of drug-naive patients at the onset of psychosis Schizophrenia Research. 15: 66. DOI: 10.1016/0920-9964(95)95208-Q  0.352
1995 Scheffer R, Mahadik SP, Correnti EE, McClure M, Mukherjee S. Membrane lipid peroxidation and neurological signs in first episode psychosis Biological Psychiatry. 37: 681. DOI: 10.1016/0006-3223(95)94728-F  0.314
1995 Scheffer R, Diamond BI, Correnti EE, Borison RL, Mahadik SP, Mukherjee S. Plasma lipid peroxidation and HVA in first episode psychosis Biological Psychiatry. 37: 681. DOI: 10.1016/0006-3223(95)94727-E  0.312
1994 Mukherjee S, Mahadik SP, Korenovsky A, Laev H, Schnur DB, Reddy R. Serum antibodies to nicotinic acetylcholine receptors in schizophrenic patients. Schizophrenia Research. 12: 131-6. PMID 8043523 DOI: 10.1016/0920-9964(94)90070-1  0.301
1994 Mahadik SP, Mukherjee S, Wakade CG, Laev H, Reddy RR, Schnur DB. Decreased adhesiveness and altered cellular distribution of fibronectin in fibroblasts from schizophrenic patients. Psychiatry Research. 53: 87-97. PMID 7991734 DOI: 10.1016/0165-1781(94)90097-3  0.303
1994 Mahadik SP, Mukherjee S, Correnti EE, Kelkar HS, Wakade CG, Costa RM, Scheffer R. Plasma membrane phospholipid and cholesterol distribution of skin fibroblasts from drug-naive patients at the onset of psychosis. Schizophrenia Research. 13: 239-47. PMID 7841137 DOI: 10.1016/0920-9964(94)90048-5  0.374
1994 Mukherjee S, Mahadik SP. A new paradigm for schizophrenia? Schizophrenia Research. 13: 191-4. PMID 7841131 DOI: 10.1016/0920-9964(94)90042-6  0.386
1994 Mukherjee S, Mahadik SP, Correnti EE, Scheffer R. The antioxidant defense system at the onset of psychosis Biological Psychiatry. 35: 701. DOI: 10.1016/0006-3223(94)90967-9  0.428
1994 Mukherjee S, Mahadik SP, Horrobin DF, Jenkins K, Correnti EE, Scheffer R. Membrane fatty acid composition of fibroblasts from schizophrenic patients Biological Psychiatry. 35: 700-701. DOI: 10.1016/0006-3223(94)90966-0  0.31
1993 Mahadik SP, Makar TK, Murthy JN, Ortiz A, Wakade CG, Karpiak SE. Temporal changes in superoxide dismutase, glutathione peroxidase, and catalase levels in primary and peri-ischemic tissue. Monosialoganglioside (GM1) treatment effects. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 18: 1-14. PMID 8466585 DOI: 10.1007/BF03160018  0.312
1992 Keshavan MS, Mahadik SP, Reynolds CF, Mukerjee S, Korenovsky A, Houck P, Jarrett DB. Plasma cholinesterase isozymes and REM latency in schizophrenia. Psychiatry Research. 43: 23-9. PMID 1438614 DOI: 10.1016/0165-1781(92)90138-S  0.309
1992 Mahadik SP, Wakade CG. Cortical focal stroke model to evaluate neuroprotective action of drugs Drug Development Research. 27: 307-327. DOI: 10.1002/ddr.430270402  0.306
1989 Mahadik SP, Mukherjee S, Korenovsky A, Reddy R, Schnur DB. Serum cholinesterase isozymes in schizophrenia Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91835-0  0.363
1989 Murthy JN, Mahadik SP, Mukherjee S, Reddy R, Schnur DB. Peripheral indices of free radical metabolism in schizophrenia Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91828-3  0.388
1989 Mukherjee S, Mahadik SP, Korenovsky A, Laev H, Reddy R. Serum antibodies to nicotinic acetylcholine receptors in schizophrenia Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91629-6  0.323
1988 Mahadik SP, Laev H, Korenovsky A, Karpiak SE. Haloperidol alters rat CNS cholinergic system: enzymatic and morphological analyses. Biological Psychiatry. 24: 199-217. PMID 3291956 DOI: 10.1016/0006-3223(88)90275-2  0.331
1988 Mahadik SP, Karpiak SK. Gangliosides in treatment of neural injury and disease Drug Development Research. 15: 337-360. DOI: 10.1002/Ddr.430150402  0.305
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