Linda L. Demer, M.d., Ph.D. - Publications

Affiliations: 
Bioengineering University of California, Los Angeles, Los Angeles, CA 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cai X, Tintut Y, Demer LL. A Potential New Link Between Inflammation and Vascular Calcification. Journal of the American Heart Association. 12: e028358. PMID 36537336 DOI: 10.1161/JAHA.122.028358  0.653
2021 Tintut Y, Honda HM, Demer LL. Biomolecules Orchestrating Cardiovascular Calcification. Biomolecules. 11. PMID 34680115 DOI: 10.3390/biom11101482  0.362
2020 Fong F, Xian J, Demer LL, Tintut Y. Serotonin receptor type 2B activation augments TNF-α-induced matrix mineralization in murine valvular interstitial cells. Journal of Cellular Biochemistry. PMID 32901992 DOI: 10.1002/Jcb.29847  0.312
2020 Hsu JJ, Fong F, Patel R, Qiao R, Lo K, Soundia A, Chang CC, Le V, Tseng CH, Demer LL, Tintut Y. Changes in microarchitecture of atherosclerotic calcification assessed by F-NaF PET and CT after a progressive exercise regimen in hyperlipidemic mice. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. PMID 31897996 DOI: 10.1007/S12350-019-02004-3  0.308
2019 Sallam T, Tintut Y, Demer LL. Regulation of calcific vascular and valvular disease by nuclear receptors. Current Opinion in Lipidology. PMID 31369409 DOI: 10.1097/Mol.0000000000000632  0.366
2019 Demer LL, Tintut Y. Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease. Trends in Endocrinology and Metabolism: Tem. PMID 31279666 DOI: 10.1016/J.Tem.2019.06.001  0.419
2019 Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang CC, Lee J, Demer LL, Tintut Y, Marsden AL, et al. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. Jci Insight. 5. PMID 30973827 DOI: 10.1172/Jci.Insight.124460  0.312
2018 Tintut Y, Hsu JJ, Demer LL. Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges. Frontiers in Cardiovascular Medicine. 5: 172. PMID 30533416 DOI: 10.3389/Fcvm.2018.00172  0.442
2018 Lee J, Vedula V, Baek KI, Chen J, Hsu JJ, Ding Y, Chang CC, Kang H, Small A, Fei P, Chuong CM, Li R, Demer L, Packard RRS, Marsden AL, et al. Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation. Jci Insight. 3. PMID 29997298 DOI: 10.1172/Jci.Insight.96672  0.306
2018 Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni R, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y. Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29451816 DOI: 10.1152/Ajpheart.00718.2017  0.372
2016 Hsu JJ, Lim J, Tintut Y, Demer LL. Cell-matrix mechanics and pattern formation in inflammatory cardiovascular calcification. Heart (British Cardiac Society). PMID 27406839 DOI: 10.1136/Heartjnl-2016-309667  0.419
2016 Lim J, Ehsanipour A, Hsu JJ, Lu J, Pedego T, Wu A, Walthers CM, Demer LL, Seidlits SK, Tintut Y. Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis. The American Journal of Pathology. PMID 27392969 DOI: 10.1016/J.Ajpath.2016.05.003  0.31
2016 Tintut Y, Demer LL. COMP-lex Mechanics: Matricrine Signaling. Circulation Research. 119: 184-6. PMID 27390328 DOI: 10.1161/Circresaha.116.309121  0.345
2015 Lim JJ, Li X, Lu J, Pedego TM, Demer L, Tintut Y. Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification. Journal of Cellular Biochemistry. PMID 25864564 DOI: 10.1002/Jcb.25186  0.413
2015 Tintut Y, Demer LL. Exosomes: nanosized cellular messages. Circulation Research. 116: 1281-3. PMID 25858057 DOI: 10.1161/Circresaha.115.306324  0.368
2015 Demer LL, Tintut Y. The leading edge of vascular calcification. Trends in Cardiovascular Medicine. 25: 275-7. PMID 25572012 DOI: 10.1016/J.Tcm.2014.11.010  0.546
2015 Demer LL, Boström KI. Conflicting forces of warfarin and matrix gla protein in the artery wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 9-10. PMID 25520520 DOI: 10.1161/Atvbaha.114.304793  0.641
2014 Demer LL, Tintut Y. Inflammatory, metabolic, and genetic mechanisms of vascular calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 715-23. PMID 24665125 DOI: 10.1161/Atvbaha.113.302070  0.438
2014 van Venrooij NA, Pereira RC, Tintut Y, Fishbein MC, Tumber N, Demer LL, Salusky IB, Wesseling-Perry K. FGF23 protein expression in coronary arteries is associated with impaired kidney function. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 29: 1525-32. PMID 24459137 DOI: 10.1093/Ndt/Gft523  0.356
2014 Tintut Y, Demer LL. Effects of bioactive lipids and lipoproteins on bone. Trends in Endocrinology and Metabolism: Tem. 25: 53-9. PMID 24183940 DOI: 10.1016/J.Tem.2013.10.001  0.442
2014 Li X, Garcia J, Lu J, Iriana S, Kalajzic I, Rowe D, Demer LL, Tintut Y. Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts. Journal of Cellular Biochemistry. 115: 179-88. PMID 24038594 DOI: 10.1002/Jcb.24648  0.41
2013 Lu J, Cheng H, Atti E, Shih DM, Demer LL, Tintut Y. Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice. Biochemical and Biophysical Research Communications. 431: 19-24. PMID 23291186 DOI: 10.1016/J.Bbrc.2012.12.114  0.405
2013 Sallam T, Cheng H, Demer LL, Tintut Y. Regulatory circuits controlling vascular cell calcification. Cellular and Molecular Life Sciences : Cmls. 70: 3187-97. PMID 23269436 DOI: 10.1007/S00018-012-1231-Y  0.438
2012 Wong MN, Nguyen TP, Chen TH, Hsu JJ, Zeng X, Saw A, Demer EM, Zhao X, Tintut Y, Demer LL. Preferred mitotic orientation in pattern formation by vascular mesenchymal cells. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1411-7. PMID 23064835 DOI: 10.1152/Ajpheart.00625.2012  0.355
2012 Morony S, Sage AP, Corbin T, Lu J, Tintut Y, Demer LL. Enhanced mineralization potential of vascular cells from SM2α-rankltg mice Calcified Tissue International. 91: 379-386. PMID 23052229 DOI: 10.1007/S00223-012-9655-9  0.742
2012 Chen TH, Zhu X, Pan L, Zeng X, Garfinkel A, Tintut Y, Demer LL, Zhao X, Ho CM. Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells. Biomaterials. 33: 9019-26. PMID 23010575 DOI: 10.1016/J.Biomaterials.2012.08.067  0.345
2012 Cheng H, Reddy A, Sage A, Lu J, Garfinkel A, Tintut Y, Demer LL. Focal high cell density generates a gradient of patterns in self-organizing vascular mesenchymal cells. Journal of Vascular Research. 49: 441-6. PMID 22797747 DOI: 10.1159/000339568  0.36
2012 Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A. Patterns of periodic holes created by increased cell motility. Interface Focus. 2: 457-64. PMID 22649581 DOI: 10.1098/Rsfs.2012.0001  0.641
2012 Chen TH, Hsu JJ, Zhao X, Guo C, Wong MN, Huang Y, Li Z, Garfinkel A, Ho CM, Tintut Y, Demer LL. Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics. Circulation Research. 110: 551-9. PMID 22223355 DOI: 10.1161/Circresaha.111.255927  0.348
2012 Li R, Mittelstein D, Lee J, Fang K, Majumdar R, Tintut Y, Demer LL, Hsiai TK. A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases. American Journal of Physiology. Cell Physiology. 302: C658-65. PMID 22031601 DOI: 10.1152/Ajpcell.00313.2011  0.366
2012 Pirih F, Lu J, Ye F, Bezouglaia O, Atti E, Ascenzi MG, Tetradis S, Demer L, Aghaloo T, Tintut Y. Adverse effects of hyperlipidemia on bone regeneration and strength Journal of Bone and Mineral Research. 27: 309-318. PMID 21987408 DOI: 10.1002/Jbmr.541  0.411
2012 Demer L, Tintut Y. Chapter 106 – Vascular Calcification Musclefundamental Biology and Mechanisms of Disease. 1383-1389. DOI: 10.1016/B978-0-12-381510-1.00106-X  0.346
2011 Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y. Role of cellular cholesterol metabolism in vascular cell calcification. The Journal of Biological Chemistry. 286: 33701-6. PMID 21835914 DOI: 10.1074/Jbc.M111.269639  0.432
2011 Demer L, Tintut Y. The roles of lipid oxidation products and receptor activator of nuclear factor-κb signaling in atherosclerotic calcification Circulation Research. 108: 1482-1493. PMID 21659652 DOI: 10.1161/Circresaha.110.234245  0.493
2011 Towler DA, Demer LL. Thematic series on the pathobiology of vascular calcification: an introduction. Circulation Research. 108: 1378-80. PMID 21617134 DOI: 10.1161/Circresaha.110.234419  0.413
2011 Sage AP, Lu J, Atti E, Tetradis S, Ascenzi MG, Adams DJ, Demer LL, Tintut Y. Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1197-206. PMID 21611962 DOI: 10.1002/Jbmr.312  0.39
2011 Ting TC, Miyazaki-Anzai S, Masuda M, Levi M, Demer LL, Tintut Y, Miyazaki M. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. The Journal of Biological Chemistry. 286: 23938-49. PMID 21596756 DOI: 10.1074/Jbc.M111.237065  0.423
2011 Tintut Y, Demer L. Editorial: The hemosteoblast: Friend or foe? Circulation Research. 108: 1038-1039. PMID 21527740 DOI: 10.1161/Circresaha.111.244665  0.429
2011 Byon CH, Sun Y, Chen J, Yuan K, Mao X, Heath JM, Anderson PG, Tintut Y, Demer LL, Wang D, Chen Y. Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1387-96. PMID 21454810 DOI: 10.1161/Atvbaha.110.222547  0.483
2011 Sage AP, Lu J, Tintut Y, Demer LL. Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney International. 79: 414-22. PMID 20944546 DOI: 10.1038/Ki.2010.390  0.432
2010 Sage AP, Tintut Y, Demer LL. Regulatory mechanisms in vascular calcification. Nature Reviews. Cardiology. 7: 528-36. PMID 20664518 DOI: 10.1615/Critreveukargeneexpr.V10.I2.40  0.481
2010 Tseng W, Graham LS, Geng Y, Reddy A, Lu J, Effros RB, Demer L, Tintut Y. PKA-induced receptor activator of NF-κB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification Journal of Biological Chemistry. 285: 29925-29931. PMID 20663885 DOI: 10.1074/Jbc.M110.117366  0.506
2010 Demer L, Tintut Y. The bone-vascular axis in chronic kidney disease Current Opinion in Nephrology and Hypertension. 19: 349-353. PMID 20508522 DOI: 10.1097/Mnh.0B013E32833A3D67  0.4
2010 Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y. Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids. Journal of Lipid Research. 51: 1010-6. PMID 19965598 DOI: 10.1194/Jlr.M001099  0.352
2009 Sage A, Tintut Y, Garfinkel A, Demer L. Systems biology of vascular calcification. Trends in Cardiovascular Medicine. 19: 118-23. PMID 19818947 DOI: 10.1016/J.Tcm.2009.07.002  0.321
2009 Graham LS, Parhami F, Tintut Y, Kitchen CM, Demer LL, Effros RB. Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss. Clinical Immunology (Orlando, Fla.). 133: 265-75. PMID 19699688 DOI: 10.1016/J.Clim.2009.07.011  0.381
2009 Demer LL, Tintut Y. Mechanisms linking osteoporosis with cardiovascular calcification. Current Osteoporosis Reports. 7: 42-6. PMID 19631027 DOI: 10.1007/S11914-009-0008-1  0.407
2009 Hsu JJ, Lu J, Huang MS, Geng Y, Sage AP, Bradley MN, Tontonoz P, Demer LL, Tintut Y. T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. Febs Letters. 583: 1344-8. PMID 19327357 DOI: 10.1016/J.Febslet.2009.03.039  0.369
2008 Demer LL, Sage AP, Tintut Y. Nanoscale architecture in atherosclerotic calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1882-4. PMID 18946051 DOI: 10.1161/Atvbaha.108.175711  0.394
2008 Huang MS, Sage AP, Lu J, Demer LL, Tintut Y. Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification. Biochemical and Biophysical Research Communications. 374: 553-8. PMID 18655772 DOI: 10.1016/J.Bbrc.2008.07.062  0.469
2008 Hsu JJ, Tintut Y, Demer LL. Vitamin D and osteogenic differentiation in the artery wall. Clinical Journal of the American Society of Nephrology : Cjasn. 3: 1542-7. PMID 18562594 DOI: 10.2215/Cjn.01220308  0.388
2008 Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation. 117: 2938-48. PMID 18519861 DOI: 10.1161/Circulationaha.107.743161  0.404
2008 Huang MS, Lu J, Ivanov Y, Sage AP, Tseng W, Demer LL, Tintut Y. Hyperlipidemia impairs osteoanabolic effects of PTH. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1672-9. PMID 18505371 DOI: 10.1359/Jbmr.080513  0.345
2008 Hsu JJ, Tintut Y, Demer LL. Murine models of atherosclerotic calcification. Current Drug Targets. 9: 224-8. PMID 18336241 DOI: 10.2174/138945008783755539  0.403
2008 Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, Stolina M, Kostenuik PJ, Demer LL. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation. 117: 411-20. PMID 18172035 DOI: 10.1161/Circulationaha.107.707380  0.718
2008 Demer LL, Tintut Y. A matter of degree: a commentary on "Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells". Free Radical Biology & Medicine. 44: 504-5. PMID 18005672 DOI: 10.1016/J.Freeradbiomed.2007.10.039  0.315
2008 Morony S, Dwyer D, Stolina M, Kostenuik PJ, Tintut Y, Zhang Z, Demer LL, Cattley RC, Van G. Response to letter regarding article, "Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr (-'-) mice" Circulation. 118: e19. DOI: 10.1161/Circulationaha.108.782649  0.692
2008 Yochelis A, Tintut Y, Demer LL, Garfinkel A. The formation of labyrinths, spots and stripe patterns in a biochemical approach to cardiovascular calcification New Journal of Physics. 10. DOI: 10.1088/1367-2630/10/5/055002  0.421
2007 Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis S, Demer LL, Tintut Y. Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts. The Journal of Biological Chemistry. 282: 21237-43. PMID 17522049 DOI: 10.1074/Jbc.M701341200  0.732
2007 Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME. Mineralocorticoid receptor activation promotes vascular cell calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 799-805. PMID 17234727 DOI: 10.1161/01.Atv.0000258414.59393.89  0.476
2006 Tintut Y, Demer L. Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification Journal of Investigative Medicine. 54: 395-401. PMID 17169261 DOI: 10.2310/6650.2006.06019  0.492
2006 Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. Mechanical response of a calcified plaque model to fluid shear force. Annals of Biomedical Engineering. 34: 1535-41. PMID 17006755 DOI: 10.1007/S10439-006-9182-9  0.337
2006 Demer LL, Tintut Y. Pitting phosphate transport inhibitors against vascular calcification. Circulation Research. 98: 857-9. PMID 16614308 DOI: 10.1161/01.Res.0000219673.71778.Df  0.419
2006 Abedin M, Lim J, Tang TB, Park D, Demer LL, Tintut Y. N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways. Circulation Research. 98: 727-9. PMID 16514067 DOI: 10.1161/01.Res.0000216009.68958.E6  0.41
2005 Demer LL, Tintut Y. Return to ectopia: stem cells in the artery wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1307-8. PMID 15980267 DOI: 10.1161/01.Atv.0000172633.74942.E6  0.422
2005 Tintut Y, Abedin M, Cho J, Choe A, Lim J, Demer LL. Regulation of RANKL-induced osteoclastic differentiation by vascular cells. Journal of Molecular and Cellular Cardiology. 39: 389-93. PMID 15893766 DOI: 10.1016/J.Yjmcc.2005.03.019  0.499
2005 Radcliff K, Tang TB, Lim J, Zhang Z, Abedin M, Demer LL, Tintut Y. Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways. Circulation Research. 96: 398-400. PMID 15692088 DOI: 10.1161/01.Res.0000157671.47477.71  0.405
2004 Demer LL, Abedin M. Skeleton key to vascular disease. Journal of the American College of Cardiology. 44: 1977-9. PMID 15542279 DOI: 10.1016/J.Jacc.2004.08.032  0.457
2004 Abedin M, Tintut Y, Demer LL. Mesenchymal stem cells and the artery wall. Circulation Research. 95: 671-6. PMID 15459088 DOI: 10.1161/01.Res.0000143421.27684.12  0.432
2004 Garfinkel A, Tintut Y, Petrasek D, Boström K, Demer LL. Pattern formation by vascular mesenchymal cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 9247-50. PMID 15197273 DOI: 10.1073/Pnas.0308436101  0.666
2004 Abedin M, Tintut Y, Demer LL. Vascular calcification: mechanisms and clinical ramifications. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1161-70. PMID 15155384 DOI: 10.1161/01.Atv.0000133194.94939.42  0.475
2004 Hsiai TK, Cho SK, Wong PK, Ing MH, Salazar A, Hama S, Navab M, Demer LL, Ho CM. Micro sensors: linking real-time oscillatory shear stress with vascular inflammatory responses. Annals of Biomedical Engineering. 32: 189-201. PMID 15008367 DOI: 10.1023/B:Abme.0000012739.88554.01  0.319
2004 Tintut Y, Morony S, Demer LL. Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: e6-10. PMID 14670933 DOI: 10.1161/01.Atv.0000112023.62695.7F  0.72
2004 Radcliff K, Tintut Y, Abedin M, Patel J, Demer L. IGF-I REGULATION OF IN VITRO VASCULAR CALCIFICATION Cardiovascular Pathology. 13: 185. DOI: 10.1016/J.Carpath.2004.03.558  0.509
2004 Abedin M, Tintut Y, Demer L. OMEGA-3 FATTY ACIDS REDUCE IN VITRO VASCULAR CELL CALCIFICATION Cardiovascular Pathology. 13: 183-184. DOI: 10.1016/J.Carpath.2004.03.553  0.352
2003 Tintut Y, Alfonso Z, Saini T, Radcliff K, Watson K, Boström K, Demer LL. Multilineage potential of cells from the artery wall. Circulation. 108: 2505-10. PMID 14581408 DOI: 10.1161/01.Cir.0000096485.64373.C5  0.661
2003 Hsiai TK, Cho SK, Wong PK, Ing M, Salazar A, Sevanian A, Navab M, Demer LL, Ho CM. Monocyte recruitment to endothelial cells in response to oscillatory shear stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1648-57. PMID 12958171 DOI: 10.1096/Fj.02-1064Com  0.325
2003 Demer LL, Tintut Y. Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1739-43. PMID 12958041 DOI: 10.1161/01.Atv.0000093547.63630.0F  0.534
2003 Mody N, Tintut Y, Radcliff K, Demer LL. Vascular calcification and its relation to bone calcification: possible underlying mechanisms. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 10: 177-83. PMID 12673183 DOI: 10.1067/Mnc.2003.0012  0.703
2002 Parhami F, Mody N, Gharavi N, Ballard AJ, Tintut Y, Demer LL. Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1997-2003. PMID 12412807 DOI: 10.1359/Jbmr.2002.17.11.1997  0.65
2002 Parhami F, Basseri B, Hwang J, Tintut Y, Demer LL. High-density lipoprotein regulates calcification of vascular cells. Circulation Research. 91: 570-6. PMID 12364384 DOI: 10.1161/01.Res.0000036607.05037.Da  0.494
2002 Demer LL. Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids. International Journal of Epidemiology. 31: 737-41. PMID 12177011 DOI: 10.1093/Ije/31.4.737  0.343
2002 Demer LL, Tintut Y, Parhami F. Novel mechanisms in accelerated vascular calcification in renal disease patients. Current Opinion in Nephrology and Hypertension. 11: 437-43. PMID 12105395 DOI: 10.1097/00041552-200207000-00011  0.482
2002 Demer LL. Adipose rex: fat and fats that rule differentiation. Circulation Research. 90: 241-3. PMID 11861408 DOI: 10.1161/Res.90.3.241  0.379
2002 Tintut Y, Parhami F, Tsingotjidou A, Tetradis S, Territo M, Demer LL. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. The Journal of Biological Chemistry. 277: 14221-6. PMID 11827970 DOI: 10.1074/Jbc.M111551200  0.426
2002 Tintut Y, Patel J, Territo M, Saini T, Parhami F, Demer LL. Monocyte/macrophage regulation of vascular calcification in vitro. Circulation. 105: 650-5. PMID 11827934 DOI: 10.1161/Hc0502.102969  0.519
2001 Demer LL. Cholesterol in vascular and valvular calcification Circulation. 104: 1881-1883. PMID 11602487 DOI: 10.1161/Circ.104.16.1881  0.327
2001 Demer LL. Boning up (or down) on statins Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1565-1566. PMID 11597926 DOI: 10.1161/Atvb.21.10.1565  0.38
2001 Honda HM, Hsiai T, Wortham CM, Chen M, Lin H, Navab M, Demer LL. A complex flow pattern of low shear stress and flow reversal promotes monocyte binding to endothelial cells Atherosclerosis. 158: 385-390. PMID 11583717 DOI: 10.1016/S0021-9150(01)00462-2  0.318
2001 Tintut Y, Demer LL. Recent advances in multifactorial regulation of vascular calcification Current Opinion in Lipidology. 12: 555-560. PMID 11561176 DOI: 10.1097/00041433-200110000-00012  0.512
2001 Mody N, Parhami F, Sarafian TA, Demer LL. Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radical Biology & Medicine. 31: 509-19. PMID 11498284 DOI: 10.1016/S0891-5849(01)00610-4  0.666
2001 Poggi SH, Bostrom KI, Demer LL, Skinner HC, Koos BJ. Placental calcification: A metastatic process? Placenta. 22: 591-596. PMID 11440548 DOI: 10.1053/Plac.2001.0688  0.655
2001 Parhami F, Tintut Y, Patel JK, Mody N, Hemmat A, Demer LL. Regulation of vascular calcification in atherosclerosis. Zeitschrift FüR Kardiologie. 90: 27-30. PMID 11374029 DOI: 10.1007/S003920170038  0.725
2001 Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL. Leptin enhances the calcification of vascular cells artery wall as a target of leptin Circulation Research. 88: 954-960. PMID 11349006 DOI: 10.1161/Hh0901.090975  0.47
2001 Boström K, Tsao D, Shen S, Wang Y, Demer LL. Matrix GLA protein modulates differentiation induced by bone morphogenetic protein-2 in C3H10T1/2 cells. The Journal of Biological Chemistry. 276: 14044-52. PMID 11278388 DOI: 10.1074/Jbc.M008103200  0.678
2001 Parhami F, Tintut Y, Beamer WG, Gharavi N, Goodman W, Demer LL. Atherogenic high-fat diet reduces bone mineralization in mice Journal of Bone and Mineral Research. 16: 182-188. PMID 11149483 DOI: 10.1359/Jbmr.2001.16.1.182  0.368
2000 Tintut Y, Patel J, Parhami F, Demer LL. Tumor necrosis factor-α promotes in vitro calcification of vascular cells via the cAMP pathway Circulation. 102: 2636-2642. PMID 11085968 DOI: 10.1161/01.Cir.102.21.2636  0.531
2000 Parhami F, Garfinkel A, Demer LL. Role of lipids in osteoporosis Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2346-2348. PMID 11073836 DOI: 10.1161/01.Atv.20.11.2346  0.415
2000 Boström K, Tintut Y, Kao SC, Stanford WP, Demer LL. HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells Journal of Cellular Biochemistry. 78: 210-221. PMID 10842316 DOI: 10.1002/(Sici)1097-4644(20000801)78:2<210::Aid-Jcb4>3.0.Co;2-Z  0.674
2000 Jackson SM, Demer LL. Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts. Febs Letters. 471: 119-24. PMID 10760525 DOI: 10.1016/S0014-5793(00)01372-7  0.402
2000 Law RE, Goetze S, Xi XP, Jackson S, Kawano Y, Demer L, Fishbein MC, Meehan WP, Hsueh WA. Expression and function of PPARγ in rat and human vascular smooth muscle cells Circulation. 101: 1311-1318. PMID 10725292 DOI: 10.1161/01.Cir.101.11.1311  0.37
1999 Parhami F, Jackson SM, Tintut Y, Le V, Balucan JP, Territo M, Demer LL. Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 2067-78. PMID 10620066 DOI: 10.1359/Jbmr.1999.14.12.2067  0.441
1999 Tintut Y, Parhami F, Le V, Karsenty G, Demer LL. Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. Journal of Biological Chemistry. 274: 28875-28879. PMID 10506130 DOI: 10.1074/Jbc.274.41.28875  0.363
1999 Jackson SM, Parhami F, Xi XP, Berliner JA, Hsueh WA, Law RE, Demer LL. Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2094-104. PMID 10479650 DOI: 10.1161/01.Atv.19.9.2094  0.385
1999 Demer LL, Tintut Y. Osteopontin. Between a rock and a hard plaque. Circulation Research. 84: 250-2. PMID 9933258 DOI: 10.1161/01.Res.84.2.250  0.486
1998 Watson KE, Parhami F, Shin V, Demer LL. Fibronectin and Collagen I Matrixes Promote Calcification of Vascular Cells in Vitro, Whereas Collagen IV Matrix Is Inhibitory Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1964-1971. PMID 9848891 DOI: 10.1161/01.Atv.18.12.1964  0.442
1998 Tintut Y, Parhami F, Boström K, Jackson SM, Demer LL. cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification. The Journal of Biological Chemistry. 273: 7547-53. PMID 9516456 DOI: 10.1074/Jbc.273.13.7547  0.703
1997 Parhami F, Demer LL. Arterial calcification in face of osteoporosis in ageing: can we blame oxidized lipids? Current Opinion in Lipidology. 8: 312-4. PMID 9335955 DOI: 10.1097/00041433-199710000-00010  0.427
1997 Watson KE, Abrolat ML, Malone LL, Hoeg JM, Doherty T, Detrano R, Demer LL. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation. 96: 1755-60. PMID 9323058 DOI: 10.1161/01.Cir.96.6.1755  0.361
1997 Parhami F, Boström K, Watson K, Demer LL. Role of molecular regulation in vascular calcification. Journal of Atherosclerosis and Thrombosis. 3: 90-4. PMID 9226460 DOI: 10.5551/Jat1994.3.90  0.703
1997 Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, Berliner JA, Demer LL. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation: A possible explanation for the paradox of arterial calcification in osteoporotic patients Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 680-687. PMID 9108780 DOI: 10.1161/01.Atv.17.4.680  0.482
1997 Balica M, Boström K, Shin V, Tillisch K, Demer LL. Calcifying subpopulation of bovine aortic smooth muscle cells is responsive to 17 beta-estradiol. Circulation. 95: 1954-60. PMID 9107185 DOI: 10.1161/01.Cir.95.7.1954  0.465
1997 Watson K, Schaub B, Malone L, Demer L. 3.P.375 A subpopulation of vascular cells supports hematopoiesis and expresses stem cell factor Atherosclerosis. 134: 277. DOI: 10.1016/S0021-9150(97)89451-8  0.362
1996 Watson KE, Demer LL. The atherosclerosis–calcification link? Current Opinion in Lipidology. 7: 101-104. PMID 8743903 DOI: 10.1097/00041433-199604000-00009  0.403
1996 Honda HM, Goldhaber JI, Demer LL, Weiss JN. Endothelium-dependent vasodilators do not cause propagated intercellular Ca2+ waves in vascular endothelial monolayers. Cell Calcium. 19: 97-104. PMID 8689675 DOI: 10.1016/S0143-4160(96)90078-0  0.317
1996 Navab M, Berliner JA, Watson AD, Hama SY, Territo MC, Lusis AJ, Shih DM, Van Lenten BJ, Frank JS, Demer LL, Edwards PA, Fogelman AM. The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 831-42. PMID 8673557 DOI: 10.1161/01.Atv.16.7.831  0.354
1995 Boström K, Watson KE, Stanford WP, Demer LL. Atherosclerotic calcification: Relation to developmental osteogenesis American Journal of Cardiology. 75. PMID 7863982 DOI: 10.1016/0002-9149(95)80020-S  0.693
1995 Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation. 91: 2488-96. PMID 7729036 DOI: 10.1161/01.Cir.91.9.2488  0.362
1995 Navab M, Fogelman AM, Berliner JA, Territo MC, Demer LL, Frank JS, Watson AD, Edwards PA, Lusis AJ. Pathogenesis of atherosclerosis. The American Journal of Cardiology. 76: 18C-23C. PMID 7572682 DOI: 10.1016/S0002-9149(99)80466-4  0.332
1995 Demer LL. A skeleton in the atherosclerosis closet. Circulation. 92: 2029-32. PMID 7554176 DOI: 10.1161/01.Cir.92.8.2029  0.375
1995 Qiao JH, Fishbein MC, Demer LL, Lusis AJ. Genetic determination of cartilaginous metaplasia in mouse aorta Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2265-2272. PMID 7489252 DOI: 10.1161/01.Atv.15.12.2265  0.31
1994 Demer LL, Watson KE, Boström K. Mechanism of calcification in atherosclerosis. Trends in Cardiovascular Medicine. 4: 45-49. PMID 21244909 DOI: 10.1016/1050-1738(94)90025-6  0.705
1994 Watson KE, Boström K, Ravindranath R, Lam T, Norton B, Demer LL. TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. The Journal of Clinical Investigation. 93: 2106-13. PMID 8182141 DOI: 10.1172/Jci117205  0.708
1994 Qiao JH, Xie PZ, Fishbein MC, Kreuzer J, Drake TA, Demer LL, Lusis AJ. Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 14: 1480-97. PMID 8068611 DOI: 10.1161/01.Atv.14.9.1480  0.337
1994 Chang GJ, Woo P, Honda HM, Ignarro LJ, Young L, Berliner JA, Demer LL. Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide: Dependence on pH and oxygen Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1808-1814. PMID 7947607 DOI: 10.1161/01.Atv.14.11.1808  0.308
1994 Stanford W, Bostro¨m K, Watson K, Demer L. Osteoinduction of a pluripotent mesenchymal cell line (C3H10T1/2) by endothelial cell-conditioned media Atherosclerosis. 109: 194. DOI: 10.1016/0021-9150(94)93780-X  0.349
1994 Watson K, Ravindrinath R, Bostro¨m K, Stanford W, Demer L. 25-Hydroxycholesterol induces calcification of an artery wall cell, with mineralization potentially mediated by a surface ganglioside Atherosclerosis. 109: 189. DOI: 10.1016/0021-9150(94)93758-3  0.373
1993 Boström K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL. Bone morphogenetic protein expression in human atherosclerotic lesions. The Journal of Clinical Investigation. 91: 1800-9. PMID 8473518 DOI: 10.1172/Jci116391  0.701
1993 Bennett RL, Navab M, Demer LL, Fogelman AM. A new anti-inflammatory leucine derivative, NPC-15669, inhibits growth of cultured human aortic smooth muscle cells. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 360-6. PMID 8443139 DOI: 10.1161/01.Atv.13.3.360  0.353
1993 Park JC, Siegel RJ, Demer LL. Effect of calcification and formalin fixation on in vitro distensibility of human femoral arteries. American Heart Journal. 125: 344-9. PMID 8427126 DOI: 10.1016/0002-8703(93)90010-7  0.316
1993 Demer LL, Wortham CM, Dirksen ER, Sanderson MJ. Mechanical stimulation induces intercellular calcium signaling in bovine aortic endothelial cells. The American Journal of Physiology. 264: H2094-102. PMID 8322938 DOI: 10.1152/Ajpheart.1993.264.6.H2094  0.301
1991 Mehrabian M, Demer LL, Lusis AJ. Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice Arteriosclerosis, Thrombosis, and Vascular Biology. 11: 947-957. PMID 2065045 DOI: 10.1161/01.Atv.11.4.947  0.315
1991 Liao F, Berliner JA, Mehrabian M, Navab M, Demer LL, Lusis AJ, Fogelman AM. Minimally modified low density lipoprotein Is biologically active in vivo in mice Journal of Clinical Investigation. 87: 2253-2257. PMID 2040705 DOI: 10.1172/Jci115261  0.363
1991 Demer LL. Effect of calcification on in vivo mechanical response of rabbit arteries to balloon dilation. Circulation. 83: 2083-93. PMID 2040058 DOI: 10.1161/01.Cir.83.6.2083  0.327
1987 Jain A, Demer LL, Raizner AE, Hartley CJ, Lewis JM, Roberts R. In vivo assessment of vascular dilatation during percutaneous transluminal coronary angioplasty. The American Journal of Cardiology. 60: 988-92. PMID 2960231 DOI: 10.1016/0002-9149(87)90338-9  0.301
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