Year |
Citation |
Score |
2021 |
Lee E, Bujalowski PJ, Teramoto T, Gottipati K, Scott SD, Padmanabhan R, Choi KH. Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase. Nature Communications. 12: 2530. PMID 33953197 DOI: 10.1038/s41467-021-22846-1 |
0.564 |
|
2019 |
Padmanabhan R, Sarcar SN, Miller DL. Promoter Length Affects the Initiation of T7 RNA Polymerase In Vitro: New Insights into Promoter/Polymerase Co-evolution. Journal of Molecular Evolution. PMID 31863129 DOI: 10.1007/s00239-019-09922-3 |
0.492 |
|
2019 |
Teramoto T, Huang X, Armbruster P, Padmanabhan R. Melpop strain of infection of mosquito C6/36 cells modulates dengue virus-induced host cellular transcripts and induces critical sequence alterations in dengue viral genome. Journal of Virology. PMID 31092581 DOI: 10.1128/Jvi.00581-19 |
0.367 |
|
2017 |
Teramoto T, Balasubramanian A, Choi KH, Padmanabhan R. Serotype-specific interactions among functional domains of Dengue virus 2 non-structural proteins (NS) 5 and NS3 are crucial for viral RNA replication. The Journal of Biological Chemistry. PMID 28396347 DOI: 10.1074/Jbc.M117.775643 |
0.592 |
|
2016 |
Klema VJ, Ye M, Hindupur A, Teramoto T, Gottipati K, Padmanabhan R, Choi KH. Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface. Plos Pathogens. 12: e1005451. PMID 26895240 DOI: 10.1371/Journal.Ppat.1005451 |
0.488 |
|
2015 |
Klema VJ, Padmanabhan R, Choi KH. Flaviviral Replication Complex: Coordination between RNA Synthesis and 51-RNA Capping. Viruses. 7: 4640-56. PMID 26287232 DOI: 10.3390/V7082837 |
0.587 |
|
2015 |
Padmanabhan R, Takhampunya R, Teramoto T, Choi KH. Flavivirus RNA synthesis in vitro. Methods (San Diego, Calif.). PMID 26272247 DOI: 10.1016/J.Ymeth.2015.08.002 |
0.639 |
|
2015 |
Erkizan HV, Schneider JA, Sajwan K, Graham GT, Griffin B, Chasovskikh S, Youbi SE, Kallarakal A, Chruszcz M, Padmanabhan R, Casey JL, Üren A, Toretsky JA. RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1. Nucleic Acids Research. 43: 1069-80. PMID 25564528 DOI: 10.1093/Nar/Gku1328 |
0.554 |
|
2014 |
Teramoto T, Boonyasuppayakorn S, Handley M, Choi KH, Padmanabhan R. Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness. The Journal of Biological Chemistry. 289: 22385-400. PMID 24904061 DOI: 10.1074/Jbc.M114.584466 |
0.62 |
|
2014 |
Boonyasuppayakorn S, Padmanabhan R. Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase. Methods in Molecular Biology (Clifton, N.J.). 1138: 361-73. PMID 24696348 DOI: 10.1007/978-1-4939-0348-1_22 |
0.588 |
|
2014 |
Lai H, Teramoto T, Padmanabhan R. Construction of dengue virus protease expression plasmid and in vitro protease assay for screening antiviral inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1138: 345-60. PMID 24696347 DOI: 10.1007/978-1-4939-0348-1_21 |
0.493 |
|
2014 |
Alcaraz-Estrada SL, Del Angel R, Padmanabhan R. Construction of self-replicating subgenomic dengue virus 4 (DENV4) replicon. Methods in Molecular Biology (Clifton, N.J.). 1138: 131-50. PMID 24696335 DOI: 10.1007/978-1-4939-0348-1_9 |
0.517 |
|
2014 |
Boonyasuppayakorn S, Reichert ED, Manzano M, Nagarajan K, Padmanabhan R. Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity. Antiviral Research. 106: 125-34. PMID 24680954 DOI: 10.1016/J.Antiviral.2014.03.014 |
0.407 |
|
2013 |
Alcaraz-Estrada SL, Reichert ED, Padmanabhan R. Construction of self-replicating subgenomic West Nile virus replicons for screening antiviral compounds. Methods in Molecular Biology (Clifton, N.J.). 1030: 283-99. PMID 23821276 DOI: 10.1007/978-1-62703-484-5_22 |
0.492 |
|
2013 |
Teramoto T, Chiang HS, Takhampunya R, Manzano M, Padmanabhan R, Maric M. Gamma interferon-inducible lysosomal thioreductase (GILT) ablation renders mouse fibroblasts sensitive to dengue virus replication. Virology. 441: 146-51. PMID 23642353 DOI: 10.1016/J.Virol.2013.03.017 |
0.316 |
|
2013 |
Sztuba-Solinska J, Teramoto T, Rausch JW, Shapiro BA, Padmanabhan R, Le Grice SF. Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome. Nucleic Acids Research. 41: 5075-89. PMID 23531545 DOI: 10.1093/Nar/Gkt203 |
0.514 |
|
2011 |
Manzano M, Reichert ED, Polo S, Falgout B, Kasprzak W, Shapiro BA, Padmanabhan R. Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replication. The Journal of Biological Chemistry. 286: 22521-34. PMID 21515677 DOI: 10.1074/Jbc.M111.234302 |
0.623 |
|
2010 |
Wu R, Smidansky ED, Oh HS, Takhampunya R, Padmanabhan R, Cameron CE, Peterson BR. Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses. Journal of Medicinal Chemistry. 53: 7958-66. PMID 20964406 DOI: 10.1021/Jm100593S |
0.417 |
|
2010 |
Alcaraz-Estrada SL, Manzano MI, Del Angel RM, Levis R, Padmanabhan R. Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5. The Journal of General Virology. 91: 2713-8. PMID 20631089 DOI: 10.1099/Vir.0.024083-0 |
0.486 |
|
2009 |
Agis-Juárez RA, Galván I, Medina F, Daikoku T, Padmanabhan R, Ludert JE, del Angel RM. Polypyrimidine tract-binding protein is relocated to the cytoplasm and is required during dengue virus infection in Vero cells Journal of General Virology. 90: 2893-2901. PMID 19692542 DOI: 10.1099/vir.0.013433-0 |
0.339 |
|
2008 |
Teramoto T, Kohno Y, Mattoo P, Markoff L, Falgout B, Padmanabhan R. Genome 3'-end repair in dengue virus type 2. Rna (New York, N.Y.). 14: 2645-56. PMID 18974278 DOI: 10.1261/Rna.1051208 |
0.574 |
|
2008 |
Yu L, Nomaguchi M, Padmanabhan R, Markoff L. Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication Virology. 374: 170-185. PMID 18234265 DOI: 10.1016/J.Virol.2007.12.035 |
0.634 |
|
2008 |
Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple Enzyme Activities of Flavivirus Proteins New Treatment Strategies For Dengue and Other Flaviviral Diseases. 74-86. DOI: 10.1002/0470058005.ch6 |
0.647 |
|
2007 |
Yocupicio-Monroy M, Padmanabhan R, Medina F, del Angel RM. Mosquito La protein binds to the 3′ untranslated region of the positive and negative polarity dengue virus RNAs and relocates to the cytoplasm of infected cells Virology. 357: 29-40. PMID 16962153 DOI: 10.1016/J.Virol.2006.07.042 |
0.542 |
|
2006 |
Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple enzyme activities of flavivirus proteins. Novartis Foundation Symposium. 277: 74-84; discussion 84. PMID 17319155 |
0.656 |
|
2006 |
Takhampunya R, Padmanabhan R, Ubol S. Antiviral action of nitric oxide on dengue virus type 2 replication Journal of General Virology. 87: 3003-3011. PMID 16963759 DOI: 10.1099/Vir.0.81880-0 |
0.611 |
|
2006 |
Takhampunya R, Ubol S, Houng HS, Cameron CE, Padmanabhan R. Inhibition of dengue virus replication by mycophenolic acid and ribavirin. The Journal of General Virology. 87: 1947-52. PMID 16760396 DOI: 10.1099/Vir.0.81655-0 |
0.475 |
|
2005 |
Yon C, Teramoto T, Mueller N, Phelan J, Ganesh VK, Murthy KH, Padmanabhan R. Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 280: 27412-9. PMID 15917225 DOI: 10.1074/Jbc.M501393200 |
0.656 |
|
2003 |
Nomaguchi M, Teramoto T, Yu L, Markoff L, Padmanabhan R. Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli. The Journal of Biological Chemistry. 279: 12141-51. PMID 14699096 DOI: 10.1074/Jbc.M310839200 |
0.68 |
|
2003 |
Nomaguchi M, Ackermann M, Yon C, You S, Padmanabhan R, Padmanbhan R. De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters. Journal of Virology. 77: 8831-42. PMID 12885902 |
0.665 |
|
2002 |
Bartelma G, Padmanabhan R. Expression, purification, and characterization of the RNA 5'-triphosphatase activity of dengue virus type 2 nonstructural protein 3. Virology. 299: 122-32. PMID 12167347 DOI: 10.1006/Viro.2002.1504 |
0.703 |
|
2001 |
Ackermann M, Padmanabhan R. De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. The Journal of Biological Chemistry. 276: 39926-37. PMID 11546770 DOI: 10.1074/Jbc.M104248200 |
0.744 |
|
2001 |
You S, Falgout B, Markoff L, Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5'- and 3'-terminal regions that influence RNA structure. The Journal of Biological Chemistry. 276: 15581-91. PMID 11278787 DOI: 10.1074/jbc.M010923200 |
0.813 |
|
1999 |
You S, Padmanabhan R. A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3'-end of exogenous viral RNA templates requires 5'- and 3'-terminal complementary sequence motifs of the viral RNA. The Journal of Biological Chemistry. 274: 33714-22. PMID 10559263 DOI: 10.1074/Jbc.274.47.33714 |
0.818 |
|
1999 |
Li H, Clum S, You S, Ebner KE, Padmanabhan R. The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. Journal of Virology. 73: 3108-16. PMID 10074162 DOI: 10.1128/Jvi.73.4.3108-3116.1999 |
0.79 |
|
1999 |
Murthy HM, Clum S, Padmanabhan R. Dengue virus NS3 serine protease. Crystal structure and insights into interaction of the active site with substrates by molecular modeling and structural analysis of mutational effects. The Journal of Biological Chemistry. 274: 5573-80. PMID 10026173 |
0.315 |
|
1998 |
Ide Y, Tanimoto A, Sasaguri Y, Padmanabhan R. Hepatitis C virus NS5A protein is phosphorylated in vitro by a stably bound protein kinase from HeLa cells and by cAMP-dependent protein kinase A-alpha catalytic subunit. Gene. 201: 151-8. PMID 9409782 DOI: 10.1016/S0378-1119(97)00440-X |
0.361 |
|
1997 |
Clum S, Ebner KE, Padmanabhan R. Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B. The Journal of Biological Chemistry. 272: 30715-23. PMID 9388208 DOI: 10.1074/Jbc.272.49.30715 |
0.391 |
|
1997 |
Medghalchi S, Padmanabhan R, Ketner G. Early region 4 modulates adenovirus DNA replication by two genetically separable mechanisms Virology. 236: 8-17. PMID 9299612 DOI: 10.1006/Viro.1997.8737 |
0.339 |
|
1997 |
Tanimoto A, Ide Y, Arima N, Sasaguri Y, Padmanabhan R. The amino terminal deletion mutants of hepatitis C virus nonstructural protein NS5A function as transcriptional activators in yeast. Biochemical and Biophysical Research Communications. 236: 360-4. PMID 9240441 DOI: 10.1006/Bbrc.1997.6967 |
0.379 |
|
1997 |
Ide Y, Zhang L, Chen M, Inchauspe G, Bahl C, Sasaguri Y, Padmanabhan R. Characterization of the nuclear localization signal and subcellular distribution of hepatitis C virus nonstructural protein NS5A. Gene. 182: 203-11. PMID 8982089 DOI: 10.1016/S0378-1119(96)00555-0 |
0.389 |
|
1996 |
Chen H, Campisi J, Padmanabhan R. SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor Journal of Biological Chemistry. 271: 13959-13967. PMID 8662914 DOI: 10.1074/Jbc.271.24.13959 |
0.317 |
|
1995 |
Kapoor M, Zhang L, Ramachandra M, Kusukawa J, Ebner KE, Padmanabhan R. Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5. The Journal of Biological Chemistry. 270: 19100-6. PMID 7642575 DOI: 10.1074/Jbc.270.32.19100 |
0.634 |
|
1995 |
Kapoor M, Zhang L, Mohan PM, Padmanabhan R. Synthesis and characterization of an infectious dengue virus type-2 RNA genome (New Guinea C strain). Gene. 162: 175-80. PMID 7557426 DOI: 10.1016/0378-1119(95)00332-Z |
0.625 |
|
1994 |
Chen H, Ramachandra M, Padmanabhan R. Biochemical characterization of a temperature-sensitive adenovirus DNA polymerase. Virology. 205: 364-70. PMID 7975233 DOI: 10.1006/Viro.1994.1654 |
0.341 |
|
1993 |
Zhang L, Padmanabhan R. Role of protein conformation in the processing of dengue virus type 2 nonstructural polyprotein precursor. Gene. 129: 197-205. PMID 8325506 DOI: 10.1016/0378-1119(93)90269-9 |
0.413 |
|
1992 |
Mohan PM, Padmanabhan R. Detection of stable secondary structure at the 3' terminus of dengue virus type 2 RNA. Gene. 108: 185-91. PMID 1660836 DOI: 10.1016/0378-1119(91)90433-C |
0.657 |
|
1992 |
Trirawatanapong T, Chandran B, Putnak R, Padmanabhan R. Mapping of a region of dengue virus type-2 glycoprotein required for binding by a neutralizing monoclonal antibody Gene. 116: 139-150. PMID 1634111 DOI: 10.1016/0378-1119(92)90509-N |
0.303 |
|
1991 |
Nakano R, Zhao LJ, Padmanabhan R. Overproduction of adenovirus DNA polymerase and preterminal protein in HeLa cells. Gene. 105: 173-8. PMID 1937014 DOI: 10.1016/0378-1119(91)90148-5 |
0.301 |
|
1989 |
Irie K, Mohan PM, Sasaguri Y, Putnak R, Padmanabhan R. Sequence analysis of cloned dengue virus type 2 genome (New Guinea-C strain). Gene. 75: 197-211. PMID 2714651 DOI: 10.1016/0378-1119(89)90266-7 |
0.399 |
|
1988 |
Olson K, Blair C, Padmanabhan R, Beaty B. Detection of dengue virus type 2 in Aedes albopictus by nucleic acid hybridization with strand-specific RNA probes. Journal of Clinical Microbiology. 26: 579-81. PMID 3281980 DOI: 10.1128/jcm.26.3.579-581.1988 |
0.501 |
|
1987 |
Henchal EA, Narupiti S, Feighny R, Padmanabhan R, Vakharia V. Detection of dengue virus RNA using nucleic acid hybridization. Journal of Virological Methods. 15: 187-200. PMID 2881940 DOI: 10.1016/0166-0934(87)90097-8 |
0.327 |
|
1986 |
Yaegashi T, Vakharia VN, Page K, Sasaguri Y, Feighny R, Padmanabhan R. Partial sequence analysis of cloned dengue virus type 2 genome Gene. 46: 257-267. PMID 3803928 DOI: 10.1016/0378-1119(86)90410-5 |
0.384 |
|
1978 |
Tsuruo T, Arens M, Padmanabhan R, Green M. An endodeoxyribonuclease of human KB cells. Purification and properties of the enzyme. The Journal of Biological Chemistry. 253: 3400-7. PMID 649580 |
0.312 |
|
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