R Padmanabhan - Publications

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
Molecular Biology, Microbiology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lee E, Bujalowski PJ, Teramoto T, Gottipati K, Scott SD, Padmanabhan R, Choi KH. Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase. Nature Communications. 12: 2530. PMID 33953197 DOI: 10.1038/s41467-021-22846-1  0.564
2019 Padmanabhan R, Sarcar SN, Miller DL. Promoter Length Affects the Initiation of T7 RNA Polymerase In Vitro: New Insights into Promoter/Polymerase Co-evolution. Journal of Molecular Evolution. PMID 31863129 DOI: 10.1007/s00239-019-09922-3  0.492
2019 Teramoto T, Huang X, Armbruster P, Padmanabhan R. Melpop strain of infection of mosquito C6/36 cells modulates dengue virus-induced host cellular transcripts and induces critical sequence alterations in dengue viral genome. Journal of Virology. PMID 31092581 DOI: 10.1128/Jvi.00581-19  0.367
2017 Teramoto T, Balasubramanian A, Choi KH, Padmanabhan R. Serotype-specific interactions among functional domains of Dengue virus 2 non-structural proteins (NS) 5 and NS3 are crucial for viral RNA replication. The Journal of Biological Chemistry. PMID 28396347 DOI: 10.1074/Jbc.M117.775643  0.592
2016 Klema VJ, Ye M, Hindupur A, Teramoto T, Gottipati K, Padmanabhan R, Choi KH. Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface. Plos Pathogens. 12: e1005451. PMID 26895240 DOI: 10.1371/Journal.Ppat.1005451  0.488
2015 Klema VJ, Padmanabhan R, Choi KH. Flaviviral Replication Complex: Coordination between RNA Synthesis and 51-RNA Capping. Viruses. 7: 4640-56. PMID 26287232 DOI: 10.3390/V7082837  0.587
2015 Padmanabhan R, Takhampunya R, Teramoto T, Choi KH. Flavivirus RNA synthesis in vitro. Methods (San Diego, Calif.). PMID 26272247 DOI: 10.1016/J.Ymeth.2015.08.002  0.639
2015 Erkizan HV, Schneider JA, Sajwan K, Graham GT, Griffin B, Chasovskikh S, Youbi SE, Kallarakal A, Chruszcz M, Padmanabhan R, Casey JL, Üren A, Toretsky JA. RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1. Nucleic Acids Research. 43: 1069-80. PMID 25564528 DOI: 10.1093/Nar/Gku1328  0.554
2014 Teramoto T, Boonyasuppayakorn S, Handley M, Choi KH, Padmanabhan R. Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness. The Journal of Biological Chemistry. 289: 22385-400. PMID 24904061 DOI: 10.1074/Jbc.M114.584466  0.62
2014 Boonyasuppayakorn S, Padmanabhan R. Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase. Methods in Molecular Biology (Clifton, N.J.). 1138: 361-73. PMID 24696348 DOI: 10.1007/978-1-4939-0348-1_22  0.588
2014 Lai H, Teramoto T, Padmanabhan R. Construction of dengue virus protease expression plasmid and in vitro protease assay for screening antiviral inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1138: 345-60. PMID 24696347 DOI: 10.1007/978-1-4939-0348-1_21  0.493
2014 Alcaraz-Estrada SL, Del Angel R, Padmanabhan R. Construction of self-replicating subgenomic dengue virus 4 (DENV4) replicon. Methods in Molecular Biology (Clifton, N.J.). 1138: 131-50. PMID 24696335 DOI: 10.1007/978-1-4939-0348-1_9  0.517
2014 Boonyasuppayakorn S, Reichert ED, Manzano M, Nagarajan K, Padmanabhan R. Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity. Antiviral Research. 106: 125-34. PMID 24680954 DOI: 10.1016/J.Antiviral.2014.03.014  0.407
2013 Alcaraz-Estrada SL, Reichert ED, Padmanabhan R. Construction of self-replicating subgenomic West Nile virus replicons for screening antiviral compounds. Methods in Molecular Biology (Clifton, N.J.). 1030: 283-99. PMID 23821276 DOI: 10.1007/978-1-62703-484-5_22  0.492
2013 Teramoto T, Chiang HS, Takhampunya R, Manzano M, Padmanabhan R, Maric M. Gamma interferon-inducible lysosomal thioreductase (GILT) ablation renders mouse fibroblasts sensitive to dengue virus replication. Virology. 441: 146-51. PMID 23642353 DOI: 10.1016/J.Virol.2013.03.017  0.316
2013 Sztuba-Solinska J, Teramoto T, Rausch JW, Shapiro BA, Padmanabhan R, Le Grice SF. Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome. Nucleic Acids Research. 41: 5075-89. PMID 23531545 DOI: 10.1093/Nar/Gkt203  0.514
2011 Manzano M, Reichert ED, Polo S, Falgout B, Kasprzak W, Shapiro BA, Padmanabhan R. Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replication. The Journal of Biological Chemistry. 286: 22521-34. PMID 21515677 DOI: 10.1074/Jbc.M111.234302  0.623
2010 Wu R, Smidansky ED, Oh HS, Takhampunya R, Padmanabhan R, Cameron CE, Peterson BR. Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses. Journal of Medicinal Chemistry. 53: 7958-66. PMID 20964406 DOI: 10.1021/Jm100593S  0.417
2010 Alcaraz-Estrada SL, Manzano MI, Del Angel RM, Levis R, Padmanabhan R. Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5. The Journal of General Virology. 91: 2713-8. PMID 20631089 DOI: 10.1099/Vir.0.024083-0  0.486
2009 Agis-Juárez RA, Galván I, Medina F, Daikoku T, Padmanabhan R, Ludert JE, del Angel RM. Polypyrimidine tract-binding protein is relocated to the cytoplasm and is required during dengue virus infection in Vero cells Journal of General Virology. 90: 2893-2901. PMID 19692542 DOI: 10.1099/vir.0.013433-0  0.339
2008 Teramoto T, Kohno Y, Mattoo P, Markoff L, Falgout B, Padmanabhan R. Genome 3'-end repair in dengue virus type 2. Rna (New York, N.Y.). 14: 2645-56. PMID 18974278 DOI: 10.1261/Rna.1051208  0.574
2008 Yu L, Nomaguchi M, Padmanabhan R, Markoff L. Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication Virology. 374: 170-185. PMID 18234265 DOI: 10.1016/J.Virol.2007.12.035  0.634
2008 Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple Enzyme Activities of Flavivirus Proteins New Treatment Strategies For Dengue and Other Flaviviral Diseases. 74-86. DOI: 10.1002/0470058005.ch6  0.647
2007 Yocupicio-Monroy M, Padmanabhan R, Medina F, del Angel RM. Mosquito La protein binds to the 3′ untranslated region of the positive and negative polarity dengue virus RNAs and relocates to the cytoplasm of infected cells Virology. 357: 29-40. PMID 16962153 DOI: 10.1016/J.Virol.2006.07.042  0.542
2006 Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple enzyme activities of flavivirus proteins. Novartis Foundation Symposium. 277: 74-84; discussion 84. PMID 17319155  0.656
2006 Takhampunya R, Padmanabhan R, Ubol S. Antiviral action of nitric oxide on dengue virus type 2 replication Journal of General Virology. 87: 3003-3011. PMID 16963759 DOI: 10.1099/Vir.0.81880-0  0.611
2006 Takhampunya R, Ubol S, Houng HS, Cameron CE, Padmanabhan R. Inhibition of dengue virus replication by mycophenolic acid and ribavirin. The Journal of General Virology. 87: 1947-52. PMID 16760396 DOI: 10.1099/Vir.0.81655-0  0.475
2005 Yon C, Teramoto T, Mueller N, Phelan J, Ganesh VK, Murthy KH, Padmanabhan R. Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 280: 27412-9. PMID 15917225 DOI: 10.1074/Jbc.M501393200  0.656
2003 Nomaguchi M, Teramoto T, Yu L, Markoff L, Padmanabhan R. Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli. The Journal of Biological Chemistry. 279: 12141-51. PMID 14699096 DOI: 10.1074/Jbc.M310839200  0.68
2003 Nomaguchi M, Ackermann M, Yon C, You S, Padmanabhan R, Padmanbhan R. De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters. Journal of Virology. 77: 8831-42. PMID 12885902  0.665
2002 Bartelma G, Padmanabhan R. Expression, purification, and characterization of the RNA 5'-triphosphatase activity of dengue virus type 2 nonstructural protein 3. Virology. 299: 122-32. PMID 12167347 DOI: 10.1006/Viro.2002.1504  0.703
2001 Ackermann M, Padmanabhan R. De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. The Journal of Biological Chemistry. 276: 39926-37. PMID 11546770 DOI: 10.1074/Jbc.M104248200  0.744
2001 You S, Falgout B, Markoff L, Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5'- and 3'-terminal regions that influence RNA structure. The Journal of Biological Chemistry. 276: 15581-91. PMID 11278787 DOI: 10.1074/jbc.M010923200  0.813
1999 You S, Padmanabhan R. A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3'-end of exogenous viral RNA templates requires 5'- and 3'-terminal complementary sequence motifs of the viral RNA. The Journal of Biological Chemistry. 274: 33714-22. PMID 10559263 DOI: 10.1074/Jbc.274.47.33714  0.818
1999 Li H, Clum S, You S, Ebner KE, Padmanabhan R. The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. Journal of Virology. 73: 3108-16. PMID 10074162 DOI: 10.1128/Jvi.73.4.3108-3116.1999  0.79
1999 Murthy HM, Clum S, Padmanabhan R. Dengue virus NS3 serine protease. Crystal structure and insights into interaction of the active site with substrates by molecular modeling and structural analysis of mutational effects. The Journal of Biological Chemistry. 274: 5573-80. PMID 10026173  0.315
1998 Ide Y, Tanimoto A, Sasaguri Y, Padmanabhan R. Hepatitis C virus NS5A protein is phosphorylated in vitro by a stably bound protein kinase from HeLa cells and by cAMP-dependent protein kinase A-alpha catalytic subunit. Gene. 201: 151-8. PMID 9409782 DOI: 10.1016/S0378-1119(97)00440-X  0.361
1997 Clum S, Ebner KE, Padmanabhan R. Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B. The Journal of Biological Chemistry. 272: 30715-23. PMID 9388208 DOI: 10.1074/Jbc.272.49.30715  0.391
1997 Medghalchi S, Padmanabhan R, Ketner G. Early region 4 modulates adenovirus DNA replication by two genetically separable mechanisms Virology. 236: 8-17. PMID 9299612 DOI: 10.1006/Viro.1997.8737  0.339
1997 Tanimoto A, Ide Y, Arima N, Sasaguri Y, Padmanabhan R. The amino terminal deletion mutants of hepatitis C virus nonstructural protein NS5A function as transcriptional activators in yeast. Biochemical and Biophysical Research Communications. 236: 360-4. PMID 9240441 DOI: 10.1006/Bbrc.1997.6967  0.379
1997 Ide Y, Zhang L, Chen M, Inchauspe G, Bahl C, Sasaguri Y, Padmanabhan R. Characterization of the nuclear localization signal and subcellular distribution of hepatitis C virus nonstructural protein NS5A. Gene. 182: 203-11. PMID 8982089 DOI: 10.1016/S0378-1119(96)00555-0  0.389
1996 Chen H, Campisi J, Padmanabhan R. SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor Journal of Biological Chemistry. 271: 13959-13967. PMID 8662914 DOI: 10.1074/Jbc.271.24.13959  0.317
1995 Kapoor M, Zhang L, Ramachandra M, Kusukawa J, Ebner KE, Padmanabhan R. Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5. The Journal of Biological Chemistry. 270: 19100-6. PMID 7642575 DOI: 10.1074/Jbc.270.32.19100  0.634
1995 Kapoor M, Zhang L, Mohan PM, Padmanabhan R. Synthesis and characterization of an infectious dengue virus type-2 RNA genome (New Guinea C strain). Gene. 162: 175-80. PMID 7557426 DOI: 10.1016/0378-1119(95)00332-Z  0.625
1994 Chen H, Ramachandra M, Padmanabhan R. Biochemical characterization of a temperature-sensitive adenovirus DNA polymerase. Virology. 205: 364-70. PMID 7975233 DOI: 10.1006/Viro.1994.1654  0.341
1993 Zhang L, Padmanabhan R. Role of protein conformation in the processing of dengue virus type 2 nonstructural polyprotein precursor. Gene. 129: 197-205. PMID 8325506 DOI: 10.1016/0378-1119(93)90269-9  0.413
1992 Mohan PM, Padmanabhan R. Detection of stable secondary structure at the 3' terminus of dengue virus type 2 RNA. Gene. 108: 185-91. PMID 1660836 DOI: 10.1016/0378-1119(91)90433-C  0.657
1992 Trirawatanapong T, Chandran B, Putnak R, Padmanabhan R. Mapping of a region of dengue virus type-2 glycoprotein required for binding by a neutralizing monoclonal antibody Gene. 116: 139-150. PMID 1634111 DOI: 10.1016/0378-1119(92)90509-N  0.303
1991 Nakano R, Zhao LJ, Padmanabhan R. Overproduction of adenovirus DNA polymerase and preterminal protein in HeLa cells. Gene. 105: 173-8. PMID 1937014 DOI: 10.1016/0378-1119(91)90148-5  0.301
1989 Irie K, Mohan PM, Sasaguri Y, Putnak R, Padmanabhan R. Sequence analysis of cloned dengue virus type 2 genome (New Guinea-C strain). Gene. 75: 197-211. PMID 2714651 DOI: 10.1016/0378-1119(89)90266-7  0.399
1988 Olson K, Blair C, Padmanabhan R, Beaty B. Detection of dengue virus type 2 in Aedes albopictus by nucleic acid hybridization with strand-specific RNA probes. Journal of Clinical Microbiology. 26: 579-81. PMID 3281980 DOI: 10.1128/jcm.26.3.579-581.1988  0.501
1987 Henchal EA, Narupiti S, Feighny R, Padmanabhan R, Vakharia V. Detection of dengue virus RNA using nucleic acid hybridization. Journal of Virological Methods. 15: 187-200. PMID 2881940 DOI: 10.1016/0166-0934(87)90097-8  0.327
1986 Yaegashi T, Vakharia VN, Page K, Sasaguri Y, Feighny R, Padmanabhan R. Partial sequence analysis of cloned dengue virus type 2 genome Gene. 46: 257-267. PMID 3803928 DOI: 10.1016/0378-1119(86)90410-5  0.384
1978 Tsuruo T, Arens M, Padmanabhan R, Green M. An endodeoxyribonuclease of human KB cells. Purification and properties of the enzyme. The Journal of Biological Chemistry. 253: 3400-7. PMID 649580  0.312
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