| Year |
Citation |
Score |
| 1992 |
Breder CD, Smith WL, Raz A, Masferrer J, Seibert K, Needleman P, Saper CB. Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brain. The Journal of Comparative Neurology. 322: 409-38. PMID 1517485 DOI: 10.1002/cne.903220309 |
0.449 |
|
| 1991 |
Spencer SE, Kibbe MR, Hurley KM, Needleman P, Saper CB. Origin of porcine brain natriuretic peptide-like immunoreactive innervation of the middle cerebral artery in the rat. Neuroscience Letters. 128: 217-20. PMID 1834966 DOI: 10.1016/0304-3940(91)90264-T |
0.447 |
|
| 1990 |
Saper CB, Kibbe MR, Hurley KM, Spencer S, Holmes HR, Leahy KM, Needleman P. Brain natriuretic peptide-like immunoreactive innervation of the cardiovascular and cerebrovascular systems in the rat. Circulation Research. 67: 1345-54. PMID 1978807 DOI: 10.1161/01.Res.67.6.1345 |
0.47 |
|
| 1989 |
Needleman P, Blaine EH, Greenwald JE, Michener ML, Saper CB, Stockmann PT, Tolunay HE. The biochemical pharmacology of atrial peptides. Annual Review of Pharmacology and Toxicology. 29: 23-54. PMID 2524996 DOI: 10.1146/annurev.pa.29.040189.000323 |
0.428 |
|
| 1989 |
Saper CB, Hurley KM, Moga MM, Holmes HR, Adams SA, Leahy KM, Needleman P. Brain natriuretic peptides: differential localization of a new family of neuropeptides. Neuroscience Letters. 96: 29-34. PMID 2522605 DOI: 10.1016/0304-3940(89)90238-3 |
0.442 |
|
| 1988 |
Standaert DG, Needleman P, Day ML, Weigand R, Krause JE. Expression of the gene for preproatriopeptin in the central nervous system of the rat. Brain Research. 464: 7-13. PMID 2460196 DOI: 10.1016/0169-328X(88)90012-5 |
0.498 |
|
| 1987 |
Standaert DG, Cechetto DF, Needleman P, Saper CB. Inhibition of the firing of vasopressin neurons by atriopeptin. Nature. 329: 151-3. PMID 2957595 DOI: 10.1038/329151a0 |
0.601 |
|
| 1987 |
Day ML, Schwartz D, Wiegand RC, Stockman PT, Brunnert SR, Tolunay HE, Currie MG, Standaert DG, Needleman P. Ventricular atriopeptin. Unmasking of messenger RNA and peptide synthesis by hypertrophy or dexamethasone. Hypertension. 9: 485-91. PMID 2952591 DOI: 10.1161/01.Hyp.9.5.485 |
0.445 |
|
| 1986 |
Standaert DG, Needleman P, Saper CB. Organization of atriopeptin-like immunoreactive neurons in the central nervous system of the rat. The Journal of Comparative Neurology. 253: 315-41. PMID 2947936 DOI: 10.1002/cne.902530304 |
0.574 |
|
| 1985 |
Needleman P, Adams SP, Cole BR, Currie MG, Geller DM, Michener ML, Saper CB, Schwartz D, Standaert DG. Atriopeptins as cardiac hormones. Hypertension. 7: 469-82. PMID 2989170 DOI: 10.1161/01.Hyp.7.4.469 |
0.528 |
|
| 1985 |
Saper CB, Standaert DG, Currie MG, Schwartz D, Geller DM, Needleman P. Atriopeptin-immunoreactive neurons in the brain: presence in cardiovascular regulatory areas. Science (New York, N.Y.). 227: 1047-9. PMID 2858127 DOI: 10.1126/science.2858127 |
0.578 |
|
| 1976 |
Douglas JR, Johnson EM, Heist JF, Marshall GR, Needleman P. Is the peripheral sympatho-adrenal nervous system necessary for renal hypertension? The Journal of Pharmacology and Experimental Therapeutics. 196: 35-43. PMID 1246014 |
0.433 |
|
| 1975 |
Douglas JR, Johnson EM, Marshall GR, Heist J, Hartman BK, Needleman P. Development and maintenance of renal hypertension in normal and guanethidine sympathectomized rats. Circulation Research. 36: 171-8. PMID 1093753 DOI: 10.1161/01.Res.36.6.171 |
0.445 |
|
| 1974 |
Johnson EM, Marshall GR, Needleman P. Modification of responses to sympathetic nerve stimulation by the renin-angiotensin system in rats. British Journal of Pharmacology. 51: 541-7. PMID 4375530 DOI: 10.1111/J.1476-5381.1974.Tb09672.X |
0.437 |
|
| 1974 |
Needleman P, Marshall GR, Johnson EM. Determinants and modification of adrenergic and vascular resistance in the kidney. The American Journal of Physiology. 227: 665-9. PMID 4369912 DOI: 10.1152/ajplegacy.1974.227.3.665 |
0.363 |
|
| 1974 |
Needleman P, Douglas JR, Jakschik B, Stoecklein PB, Johnson EM. Release of renal prostaglandin by catecholamines: relationship to renal endocrine function. The Journal of Pharmacology and Experimental Therapeutics. 188: 453-60. PMID 4359555 |
0.406 |
|
| 1973 |
Ferrendelli JA, Johnson EM, Chang M, Needleman P. Inhibition of brain adenylate cyclase by ethacrynic acid and dithiobisnitrobenzoic acid. Biochemical Pharmacology. 22: 3133-6. PMID 4761572 DOI: 10.1016/0006-2952(73)90206-2 |
0.363 |
|
| 1973 |
Johnson EM, Lang S, Needleman P. Dissociation of sympathetic compensation from glyceryl trinitrate tolerance. European Journal of Pharmacology. 21: 189-94. PMID 4633119 DOI: 10.1016/0014-2999(73)90225-2 |
0.387 |
|
| 1973 |
Needleman P, Johnson EM. Mechanism of tolerance development to organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 184: 709-15. PMID 4631470 |
0.336 |
|
| 1973 |
Needleman P, Kauffman AH, Douglas JR, Johnson EM, Marshall GR. Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs. The American Journal of Physiology. 224: 1415-9. PMID 4351298 DOI: 10.1152/ajplegacy.1973.224.6.1415 |
0.417 |
|
| 1973 |
Douglas JR, Johnson EM, Marshall GR, Jaffe BM, Needleman P. Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII. Prostaglandins. 3: 67-74. PMID 4348364 DOI: 10.1016/0090-6980(73)90138-X |
0.394 |
|
| 1973 |
Needleman P, Jakschik B, Johnson EM. Sulfhydryl requirement for relaxation of vascular smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. 187: 324-31. PMID 4201275 |
0.323 |
|
| 1972 |
Johnson EM, Harkey AB, Blehm DJ, Needleman P. Clearance and metabolism of organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 182: 56-62. PMID 4625289 |
0.362 |
|
| 1972 |
Needleman P, Lang S, Johnson EM. Organic nitrates: relationship between biotransformation and rational angina pectoris therapy. The Journal of Pharmacology and Experimental Therapeutics. 181: 489-97. PMID 4624401 |
0.334 |
|
| 1972 |
Lang S, Johnson EM, Needleman P. Metabolism of and vascular responses to glyceryl trinitrate in the eviscerated rat. Biochemical Pharmacology. 21: 422-4. PMID 4622561 DOI: 10.1016/0006-2952(72)90356-5 |
0.403 |
|
| 1972 |
Blaustein MP, Johnson EM, Needleman P. Calcium-dependent norepinephrine release from presynaptic nerve endings in vitro. Proceedings of the National Academy of Sciences of the United States of America. 69: 2237-40. PMID 4506092 DOI: 10.1073/Pnas.69.8.2237 |
0.364 |
|
| 1972 |
Needleman P, Johnson EM, Vine W, Flanigan E, Marshall GR. Pharmacology of antagonists of angiotensin I and II. Circulation Research. 31: 862-7. PMID 4345101 DOI: 10.1161/01.Res.31.6.862 |
0.354 |
|
| 1971 |
Needleman P, Blehm DJ, Harkey AB, Johnson EM, Lang S. The metabolic pathway in the degradation of glyceryl trinitrate. The Journal of Pharmacology and Experimental Therapeutics. 179: 347-53. PMID 5002725 |
0.342 |
|
| 1968 |
Needleman P, Passonneau JV, Lowry OH. Distribution of glucose and related metabolites in rat kidney. The American Journal of Physiology. 215: 655-9. PMID 5671004 DOI: 10.1152/ajplegacy.1968.215.3.655 |
0.459 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1985 |
Wakitani K, Oshima T, Loewy AD, Holmberg SW, Cole BR, Adams SP, Fok KF, Currie MG, Needleman P. Comparative vascular pharmacology of the atriopeptins. Circulation Research. 56: 621-7. PMID 3156691 |
0.252 |
|
| 1991 |
Greenwald JE, Needleman P, Wilkins MR, Schreiner GF. Renal synthesis of atriopeptin-like protein in physiology and pathophysiology. The American Journal of Physiology. 260: F602-7. PMID 1826411 |
0.245 |
|
| 1985 |
Wakitani K, Currie MG, Geller DM, Needleman P. Vasodilator properties of a family of bioactive atrial peptides in isolated perfused rat kidneys. The Journal of Laboratory and Clinical Medicine. 105: 349-52. PMID 3156197 |
0.244 |
|
| 1984 |
Oshima T, Currie MG, Geller DM, Needleman P. An atrial peptide is a potent renal vasodilator substance. Circulation Research. 54: 612-6. PMID 6233046 |
0.24 |
|
| 1986 |
Cole BR, Schwartz D, Manning PT, Katsube NC, Needleman P. Atriopeptins: circulating volume regulatory hormones with potential therapeutic role in chronic renal failure. Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension. 4: S13-6. PMID 2941535 |
0.24 |
|
| 1986 |
Thorén P, Mark AL, Morgan DA, O'Neill TP, Needleman P, Brody MJ. Activation of vagal depressor reflexes by atriopeptins inhibits renal sympathetic nerve activity. The American Journal of Physiology. 251: H1252-9. PMID 2947476 DOI: 10.1152/Ajpheart.1986.251.6.H1252 |
0.233 |
|
| 1992 |
Wilkins MR, Needleman P. Effect of pharmacological manipulation of endogenous atriopeptin activity on renal function. The American Journal of Physiology. 262: F161-7. PMID 1311520 |
0.231 |
|
| 1986 |
Needleman P. Atriopeptin biochemical pharmacology. Federation Proceedings. 45: 2096-100. PMID 3011519 |
0.231 |
|
| 1984 |
Oshima T, Currie MG, Geller DM, Needleman P. A rat cardiac atrial peptide, atriopeptin II, is a selective renal vasodilator in vivo Federation Proceedings. 43: no. 989. |
0.23 |
|
| 1990 |
Wilkins MR, Settle SL, Stockmann PT, Needleman P. Maximizing the natriuretic effect of endogenous atriopeptin in a rat model of heart failure. Proceedings of the National Academy of Sciences of the United States of America. 87: 6465-9. PMID 2166956 |
0.229 |
|
| 1985 |
Wakitani K, Cole BR, Geller DM, Currie MG, Adams SP, Fok KF, Needleman P. Atriopeptins: correlation between renal vasodilation and natriuresis. The American Journal of Physiology. 249: F49-53. PMID 3160248 |
0.223 |
|
| 1985 |
Cole BR, Kuhnline MA, Needleman P. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. The Journal of Clinical Investigation. 76: 2413-5. PMID 2934412 DOI: 10.1172/JCI112254 |
0.222 |
|
| 1991 |
Rutherford RA, Wharton J, Needleman P, Polak JM. Autoradiographic discrimination of brain and atrial natriuretic peptide-binding sites in the rat kidney. The Journal of Biological Chemistry. 266: 5819-26. PMID 1826004 |
0.222 |
|
| 1988 |
Greenwald JE, Sakata M, Michener ML, Sides SD, Needleman P. Is atriopeptin a physiological or pathophysiological substance? Studies in the autoimmune rat. The Journal of Clinical Investigation. 81: 1036-41. PMID 2965162 DOI: 10.1172/JCI113414 |
0.22 |
|
| 1986 |
Schwartz D, Katsube NC, Needleman P. Atriopeptin release in conditions of altered salt and water balance in the rat. Biochemical and Biophysical Research Communications. 137: 922-8. PMID 2942144 DOI: 10.1016/0006-291X(86)90313-X |
0.22 |
|
| 1988 |
Sakata M, Needleman P. Strategies for the in vivo inhibition of endogenous atriopeptin. Biochemical and Biophysical Research Communications. 155: 990-5. PMID 2971357 DOI: 10.1016/S0006-291X(88)80594-1 |
0.21 |
|
| 1986 |
Wei YF, Geller D, Siegel NR, Needleman P. Identification of the cardiac and circulating form of atriopeptin in rabbit. Biochemical and Biophysical Research Communications. 138: 1263-8. PMID 2944516 DOI: 10.1016/S0006-291X(86)80419-3 |
0.21 |
|
| 1991 |
Ritter D, Needleman P, Greenwald JE. Synthesis and secretion of an atriopeptin-like protein in rat kidney cell culture. The Journal of Clinical Investigation. 87: 208-12. PMID 1824632 DOI: 10.1172/JCI114973 |
0.208 |
|
| 1983 |
Okegawa T, Jonas PE, DeSchryver K, Kawasaki A, Needleman P. Metabolic and cellular alterations underlying the exaggerated renal prostaglandin and thromboxane synthesis in ureter obstruction in rabbits. Inflammatory response involving fibroblasts and mononuclear cells. The Journal of Clinical Investigation. 71: 81-90. PMID 6848562 |
0.207 |
|
| 1987 |
Albrightson CR, Evers AS, Griffin AC, Needleman P. Effect of endogenously produced leukotrienes and thromboxane on renal vascular resistance in rabbit hydronephrosis. Circulation Research. 61: 514-22. PMID 2820607 |
0.206 |
|
| 1985 |
Lefkowith JB, Flippo V, Sprecher H, Needleman P. Paradoxical conservation of cardiac and renal arachidonate content in essential fatty acid deficiency. The Journal of Biological Chemistry. 260: 15736-44. PMID 3934163 |
0.206 |
|
| 1988 |
Ito T, Toki Y, Siegel N, Gierse JK, Needleman P. Manipulation of stretch-induced atriopeptin prohormone release and processing in the perfused rat heart. Proceedings of the National Academy of Sciences of the United States of America. 85: 8365-9. PMID 2973064 |
0.205 |
|
| 1992 |
Pucci A, Wharton J, Arbustini E, Grasso M, Diegoli M, Needleman P, Viganò M, Moscoso G, Polak JM. Localization of brain and atrial natriuretic peptide in human and porcine heart. International Journal of Cardiology. 34: 237-47. PMID 1532953 DOI: 10.1016/0167-5273(92)90020-4 |
0.205 |
|
| 1978 |
Needleman P, Bronson SD, Wyche A, Sivakoff M, Nicolaou KC. Cardiac and renal prostaglandin I2. Biosynthesis and biological effects in isolated perfused rabbit tissues. The Journal of Clinical Investigation. 61: 839-49. PMID 346605 DOI: 10.1172/Jci108998 |
0.204 |
|
| 1986 |
Michener ML, Gierse JK, Seetharam R, Fok KF, Olins PO, Mai MS, Needleman P. Proteolytic processing of atriopeptin prohormone. Molecular Pharmacology. 30: 552-7. PMID 2946928 |
0.203 |
|
| 1992 |
Ritter D, Chao J, Needleman P, Tetens E, Greenwald JE. Localization, synthetic regulation, and biology of renal atriopeptin-like prohormone. The American Journal of Physiology. 263: F503-9. PMID 1357979 |
0.203 |
|
| 1983 |
Jonas PE, DeSchryver K, Okegawa T, Leahy K, Needleman P. Presence of inflammatory cells associated with exaggerated arachidonic acid metabolism in renal injury. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 12: 65-73. PMID 6221640 |
0.203 |
|
| 1987 |
Wei YF, Holmberg SW, Leahy KM, Olins PO, Devine CS, Needleman P. Heparin interferes with the biological effectiveness of atriopeptin. Hypertension. 9: 607-10. PMID 2953683 |
0.203 |
|
| 1986 |
Goetz KL, Wang BC, Geer PG, Sundet WD, Needleman P. Effects of atriopeptin infusion versus effects of left atrial stretch in awake dogs. The American Journal of Physiology. 250: R221-6. PMID 2936255 |
0.202 |
|
| 1986 |
Katsube N, Schwartz D, Needleman P. Atriopeptin turnover: quantitative relationship between in vivo changes in plasma levels and atrial content. The Journal of Pharmacology and Experimental Therapeutics. 239: 474-9. PMID 2945922 |
0.201 |
|
| 1985 |
Manning PT, Schwartz D, Katsube NC, Holmberg SW, Needleman P. Vasopressin-stimulated release of atriopeptin: endocrine antagonists in fluid homeostasis. Science (New York, N.Y.). 229: 395-7. PMID 2990050 DOI: 10.1126/science.2990050 |
0.199 |
|
| 1985 |
Campbell WB, Currie MG, Needleman P. Inhibition of aldosterone biosynthesis by atriopeptins in rat adrenal cells. Circulation Research. 57: 113-8. PMID 2988817 |
0.199 |
|
| 1988 |
Sakata M, Greenwald JE, Needleman P. Paradoxical relationship between atriopeptin plasma levels and diuresis-natriuresis induced by acute volume expansion. Proceedings of the National Academy of Sciences of the United States of America. 85: 3155-9. PMID 2966400 |
0.197 |
|
| 1979 |
Puré E, Needleman P. Effect of endothelial damage on prostaglandin synthesis by isolated perfused rabbit mesenteric vasculature. Journal of Cardiovascular Pharmacology. 1: 299-309. PMID 94398 DOI: 10.1097/00005344-197905000-00003 |
0.196 |
|
| 1984 |
Schwartz D, DeSchryver-Kecskemeti K, Needleman P. Renal arachidonic acid metabolism and cellular changes in the rabbit renal vein constricted kidney: inflammation as a common process in renal injury models. Prostaglandins. 27: 605-13. PMID 6427853 DOI: 10.1016/0090-6980(84)90096-0 |
0.195 |
|
| 1985 |
Lefkowith JB, Needleman P. Arachidonate metabolism in renal injury. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 13: 121-30. PMID 3159195 |
0.195 |
|
| 1988 |
Stockman PT, Needleman P. Ventricular atriopeptin release from the hypertrophic isolated rat heart Surgical Forum. 39: 252-254. |
0.194 |
|
| 1982 |
Kawasaki A, Needleman P. Contribution of thromboxane to renal resistance changes in the isolated perfused hydronephrotic rabbit kidney. Circulation Research. 50: 486-90. PMID 7039861 |
0.193 |
|
| 1981 |
Myers SI, Zipser R, Needleman P. Peptide-induced prostaglandin biosynthesis in the renal-vein-constricted kidney. The Biochemical Journal. 198: 357-63. PMID 6798974 |
0.192 |
|
| 1984 |
Lefkowith JB, Okegawa T, DeSchryver-Kecskemeti K, Needleman P. Macrophage-dependent arachidonate metabolism in hydronephrosis. Kidney International. 26: 10-7. PMID 6434790 |
0.191 |
|
| 1976 |
Needleman P, Douglas JR, Jakschik BA, Blumberg AL, Isakson PC, Marshall GR. Angiotensin antogonists as pharmacological tools. Federation Proceedings. 35: 2488-93. PMID 185093 |
0.19 |
|
| 1979 |
Needleman P, Wyche A, Bronson SD, Holmberg S, Morrison AR. Specific regulation of peptide-induced renal prostaglandin synthesis. The Journal of Biological Chemistry. 254: 9772-9. PMID 489567 |
0.189 |
|
| 1985 |
Katsube N, Wakitani K, Fok KF, Tjoeng FS, Zupec ME, Eubanks SR, Adams SP, Needleman P. Differential structure-activity relationships of atrial peptides as natriuretics and renal vasodilators in the dog. Biochemical and Biophysical Research Communications. 128: 325-30. PMID 3157379 DOI: 10.1016/0006-291X(85)91682-1 |
0.188 |
|
| 1972 |
Jaffe BM, Parker CW, Marshall GR, Needleman P. Renal concentrations of prostaglandin E in acute and chronic renal ischemia. Biochemical and Biophysical Research Communications. 49: 799-805. PMID 4638755 DOI: 10.1016/0006-291X(72)90481-0 |
0.187 |
|
| 1996 |
Seibert K, Masferrer JL, Needleman P, Salvemini D. Pharmacological manipulation of cyclo-oxygenase-2 in the inflamed hydronephrotic kidney. British Journal of Pharmacology. 117: 1016-20. PMID 8882591 DOI: 10.1111/J.1476-5381.1996.Tb16691.X |
0.187 |
|
| 1990 |
Toki Y, Ito T, Shiono S, Siegel NR, Gierse JK, Wilkins MR, Needleman P. Alternative mechanisms for atriopeptin prohormone processing by isolated perfused rat hearts. The Journal of Pharmacology and Experimental Therapeutics. 254: 228-35. PMID 2142220 |
0.187 |
|
| 1984 |
Currie MG, Geller DM, Cole BR, Siegel NR, Fok KK, Adams SP, Eubanks SR, Galluppi GR, Needleman P. Atriopeptins: bioactive peptides derived from mammalian cardiac atria. Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension. 2: S309-12. PMID 6242557 |
0.185 |
|
| 1985 |
Schwartz D, Currie MG, Needleman P. Effects of dietary salt on cardiac atriopeptin levels in the Dahl hypertensive rat Federation Proceedings. 44: No. 2351. |
0.183 |
|
| 1977 |
Blumberg AL, Denny SE, Marshall GR, Needleman P. Blood vessel-hormone interactions: angiotensin, bradykinin, and prostaglandins. The American Journal of Physiology. 232: H305-10. PMID 842686 DOI: 10.1152/Ajpheart.1977.232.3.H305 |
0.182 |
|
| 1985 |
Schwartz D, Geller DM, Manning PT, Siegel NR, Fok KF, Smith CE, Needleman P. Ser-Leu-Arg-Arg-atriopeptin III: the major circulating form of atrial peptide. Science (New York, N.Y.). 229: 397-400. PMID 3160114 |
0.181 |
|
| 1983 |
Okegawa T, DeSchryver-Kecskemeti K, Needleman P. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. The Journal of Pharmacology and Experimental Therapeutics. 225: 213-8. PMID 6403696 |
0.18 |
|
| 1987 |
Wei YF, Rodi CP, Day ML, Wiegand RC, Needleman LD, Cole BR, Needleman P. Developmental changes in the rat atriopeptin hormonal system. The Journal of Clinical Investigation. 79: 1325-9. PMID 2952670 DOI: 10.1172/JCI112957 |
0.176 |
|
| 1984 |
Currie MG, Sukin D, Geller DM, Cole BR, Needleman P. Atriopeptin release from the isolated perfused rabbit heart. Biochemical and Biophysical Research Communications. 124: 711-7. PMID 6508779 DOI: 10.1016/0006-291X(84)91016-7 |
0.176 |
|
| 1985 |
Hintze TH, Currie MG, Needleman P. Atriopeptins: renal-specific vasodilators in conscious dogs. The American Journal of Physiology. 248: H587-91. PMID 3157328 |
0.175 |
|
| 1986 |
Shapiro JT, DeLeonardis VM, Needleman P, Hintze TH. Integrated cardiac and peripheral vascular response to atriopeptin 24 in conscious dogs. The American Journal of Physiology. 251: H1292-7. PMID 2947478 |
0.175 |
|
| 1990 |
Wilkins MR, Settle SL, Needleman P. Augmentation of the natriuretic activity of exogenous and endogenous atriopeptin in rats by inhibition of guanosine 3',5'-cyclic monophosphate degradation. The Journal of Clinical Investigation. 85: 1274-9. PMID 2156897 DOI: 10.1172/JCI114564 |
0.175 |
|
| 1985 |
Cole BR, Kuhnline MA, Currie MG, Needleman P. 1587 ATRIOPEPTIN: A POWERFUL NATRIURETIC IN RATS WITH RENAL FAILURE Pediatric Research. 19: 375A-375A. DOI: 10.1203/00006450-198504000-01611 |
0.175 |
|
| 1989 |
Hoegler C, McIntyre J, Zeballos G, Shapiro J, DeLeonardis M, Needleman P, Hintze T. Relationship between plasma atriopeptin concentration and function in the conscious primate. The Journal of Pharmacology and Experimental Therapeutics. 251: 929-36. PMID 2532250 |
0.174 |
|
| 1991 |
Pucci A, Wharton J, Arbustini E, Grasso M, Diegoli M, Needleman P, Viganò M, Polak JM. Atrial amyloid deposits in the failing human heart display both atrial and brain natriuretic peptide-like immunoreactivity. The Journal of Pathology. 165: 235-41. PMID 1837051 DOI: 10.1002/path.1711650307 |
0.173 |
|
| 1985 |
Goetz KL, Wang BC, Geer PG, Needleman P. Atriopeptin infusion and left atrial stretch cause similar renal effects in conscious dogs Federation Proceedings. 44: No. 2354. |
0.17 |
|
| 1981 |
Currie MG, Davis BB, Needleman P. Localization of exaggerated prostaglandin synthesis associated with renal damage. Prostaglandins. 22: 933-44. PMID 6950462 |
0.169 |
|
| 1978 |
Hsueh W, Needleman P. Sites of lipase activation and prostaglandin synthesis in isolated, perfused rabbit hearts and hydronephrotic kidneys Prostaglandins. 16: 661-681. DOI: 10.1016/0090-6980(78)90002-3 |
0.169 |
|
| 1979 |
Hsueh W, Needleman P. Cardiac and renal lipases and prostaglandin biosynthesis. Lipids. 14: 236-40. PMID 423722 |
0.168 |
|
| 1977 |
Blumberg AL, Nishikawa K, Denny SE, Marshall GR, Needleman P. Angiotensin (A I, A II, A III) receptor characterization. Correlation of prostaglandin release with peptide degradation. Circulation Research. 41: 154-8. PMID 194728 DOI: 10.1161/01.Res.41.2.154 |
0.168 |
|
| 1981 |
Zipser RD, Myers SI, Needleman P. Stimulation of renal prostaglandin synthesis by the pressor activity of vasopressin. Endocrinology. 108: 495-9. PMID 6893820 DOI: 10.1210/endo-108-2-495 |
0.167 |
|
| 1977 |
Isakson PC, Raz A, Denny SE, Pure E, Needleman P. A novel prostaglandin is the major product of arachidonic acid metabolism in rabbit heart. Proceedings of the National Academy of Sciences of the United States of America. 74: 101-5. PMID 264662 DOI: 10.1073/Pnas.74.1.101 |
0.165 |
|
| 1986 |
Evers AS, Elliott WJ, Lefkowith JB, Needleman P. Manipulation of rat brain fatty acid composition alters volatile anesthetic potency. The Journal of Clinical Investigation. 77: 1028-33. PMID 3949972 DOI: 10.1172/JCI112355 |
0.164 |
|
| 1980 |
Morrison AR, Pascoe N, Needleman P. Perfusion-dependent induction of de novo synthesis of renal phosphatide acyl hydrolase in ureter-obstructed rabbit kidney. The Journal of Biological Chemistry. 255: 20-2. PMID 7350153 |
0.163 |
|
| 1980 |
Zipser R, Myers S, Needleman P. Exaggerated prostaglandin and thromboxane synthesis in the rabbit with renal vein constriction. Circulation Research. 47: 231-7. PMID 7397955 |
0.163 |
|
| 1980 |
Myers S, Zipser R, Needleman P. Exaggerated prostaglandin and thromboxane synthesis in the renal vein constricted rabbit. Advances in Prostaglandin and Thromboxane Research. 7: 1171-3. PMID 7369026 |
0.163 |
|
| 1985 |
Murphy KM, McLaughlin LL, Michener ML, Needleman P. Autoradiographic localization of atriopeptin III receptors in rat kidney. European Journal of Pharmacology. 111: 291-2. PMID 3160595 DOI: 10.1016/0014-2999(85)90772-1 |
0.163 |
|
| 1983 |
Bloch MH, McLaughlin LL, Martin SA, Needleman P. Prostaglandin production by the pregnant and non-pregnant rabbit uterus. Prostaglandins. 26: 33-46. PMID 6415760 DOI: 10.1016/0090-6980(83)90072-2 |
0.163 |
|
| 1989 |
Williamson JR, Holmberg SW, Chang K, Marvel J, Sutera SP, Needleman P. Mechanisms underlying atriopeptin-induced increases in hematocrit and vascular permeation in rats. Circulation Research. 64: 890-9. PMID 2523261 DOI: 10.1161/01.Res.64.5.890 |
0.161 |
|
| 1977 |
Isakson PC, Raz A, Denny SE, Wyche A, Needleman P. Hormonal stimulation of arachidonate release from isolated perfused organs. Relationship to prostaglandin biosynthesis. Prostaglandins. 14: 853-71. PMID 594388 |
0.161 |
|
| 1988 |
Spaethe SM, Freed MS, De Schryver-Kecskemeti K, Lefkowith JB, Needleman P. Essential fatty acid deficiency reduces the inflammatory cell invasion in rabbit hydronephrosis resulting in suppression of the exaggerated eicosanoid production. The Journal of Pharmacology and Experimental Therapeutics. 245: 1088-94. PMID 3133463 |
0.161 |
|
| 1987 |
Evers AS, Dunkel CG, Saffitz JE, Needleman P. Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction. The Journal of Clinical Investigation. 79: 155-62. PMID 3098782 DOI: 10.1172/JCI112777 |
0.16 |
|
| 1986 |
Henrich WL, Needleman P, Campbell WB. Effect of atriopeptin III on renin release in vitro. Life Sciences. 39: 993-1001. PMID 3018407 DOI: 10.1016/0024-3205(86)90288-2 |
0.16 |
|
| 1984 |
Geller DM, Currie MG, Wakitani K, Cole BR, Adams SP, Fok KF, Siegel NR, Eubanks SR, Galluppi GR, Needleman P. Atriopeptins: a family of potent biologically active peptides derived from mammalian atria. Biochemical and Biophysical Research Communications. 120: 333-8. PMID 6233969 DOI: 10.1016/0006-291X(84)91258-0 |
0.16 |
|
| 1980 |
Ahumada GG, Sobel BE, Needleman P. Synthesis of prostaglandins by cultured rat hearts myocytes and cardiac mesenchymal cells. Journal of Molecular and Cellular Cardiology. 12: 685-700. PMID 6893342 DOI: 10.1016/0022-2828(80)90099-1 |
0.159 |
|
| 1983 |
Sheng WY, Lysz TA, Wyche A, Needleman P. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. The Journal of Biological Chemistry. 258: 2188-92. PMID 6401732 |
0.159 |
|
| 1977 |
Isakson PC, Shofer F, McKnight RC, Feldhaus RA, Raz A, Needleman P. Prostaglandins and the renin-angiotensin system in canine endotoxemia. The Journal of Pharmacology and Experimental Therapeutics. 200: 614-22. PMID 850131 |
0.158 |
|
| 1979 |
Smith WL, Bell TG, Needleman P. Increased renal tubular synthesis of prostaglandins in the rabbit kidney in response to ureteral obstruction. Prostaglandins. 18: 269-77. PMID 118489 |
0.157 |
|
| 1994 |
Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. The Journal of Clinical Investigation. 93: 1940-7. PMID 7514189 DOI: 10.1172/Jci117185 |
0.156 |
|
| 1984 |
Needleman P, Currie MG, Geller DM, Cole BR, Adams SP. Atriopeptins: potential mediators of an endocrine relationship between heart and kidney Trends in Pharmacological Sciences. 5: 506-509. DOI: 10.1016/0165-6147(84)90528-5 |
0.156 |
|
| 1984 |
Currie MG, Needleman P. Renal arachidonic acid metabolism. Annual Review of Physiology. 46: 327-41. PMID 6370112 DOI: 10.1146/annurev.ph.46.030184.001551 |
0.155 |
|
| 1973 |
Minkes MS, Douglas JR, Needleman P. Prostaglandin release by the isolated perfused rabbit heart. Prostaglandins. 3: 439-45. PMID 4354088 |
0.153 |
|
| 1986 |
Schwartz D, Katsube NC, Needleman P. Atriopeptins in fluid and electrolyte homeostasis. Federation Proceedings. 45: 2361-5. PMID 2942422 |
0.153 |
|
| 1985 |
Katsube N, Schwartz D, Needleman P. Release of atriopeptin in the rat by vasoconstrictors or water immersion correlates with changes in right atrial pressure. Biochemical and Biophysical Research Communications. 133: 937-44. PMID 2935154 DOI: 10.1016/0006-291X(85)91226-4 |
0.153 |
|
| 1982 |
Yusheng W, Wyche A, Lysz T, Needleman P. Kinetics of renal arachidonate metabolism in hydronephrosis Federation Proceedings. 41: 7452. |
0.152 |
|
| 1989 |
Freed MS, Needleman P, Dunkel CG, Saffitz JE, Evers AS. Role of invading leukocytes in enhanced atrial eicosanoid production following rabbit left ventricular myocardial infarction. The Journal of Clinical Investigation. 83: 205-12. PMID 2492036 DOI: 10.1172/JCI113860 |
0.152 |
|
| 1989 |
Greenwald JE, Apkon M, Hruska KA, Needleman P. Stretch-induced atriopeptin secretion in the isolated rat myocyte and its negative modulation by calcium. The Journal of Clinical Investigation. 83: 1061-5. PMID 2522102 DOI: 10.1172/JCI113948 |
0.151 |
|
| 1971 |
Needleman P, Harkey AB. Role of endogenous glutathione in the metabolism of glyceryl trinitrate by isolated perfused rat liver. Biochemical Pharmacology. 20: 1867-76. PMID 5002952 |
0.15 |
|
| 1974 |
Jakschik BA, Marshall GR, Kourik JL, Needleman P. Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation. The Journal of Clinical Investigation. 54: 842-52. PMID 4372250 DOI: 10.1172/Jci107824 |
0.149 |
|
| 1991 |
Shiono S, Suganuma N, Bo M, Boime I, Seibert K, Nakao K, Mukoyama M, Imura H, Needleman P. Post-translational processing and secretory pathway of human atriopeptin in rat pheochromocytoma cells. Biochemical and Biophysical Research Communications. 176: 1232-8. PMID 1828150 DOI: 10.1016/0006-291X(91)90417-6 |
0.149 |
|
| 1974 |
Needleman P, Minkes MS, Douglas JR. Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of prostaglandin release by perfused organs. Circulation Research. 34: 455-60. PMID 4363763 |
0.148 |
|
| 1985 |
Cole BR, Kuhnline MA, Currie MG, Needleman P. Vascular and natriuretic effects of atriopeptin III in reduced renal mass Federation Proceedings. 44: No. 6788. |
0.148 |
|
| 1973 |
Swanson LW, Marshall GR, Needleman P, Sharpe LG. Characterization of central angiotensin II receptors involved in the elicitation of drinking in the rat. Brain Research. 49: 441-6. PMID 4352731 DOI: 10.1016/0006-8993(73)90438-1 |
0.147 |
|
| 1998 |
Venturini CM, Isakson P, Needleman P. Non-steroidal anti-inflammatory drug-induced renal failure: a brief review of the role of cyclo-oxygenase isoforms. Current Opinion in Nephrology and Hypertension. 7: 79-82. PMID 9442367 DOI: 10.1097/00041552-199801000-00013 |
0.146 |
|
| 1989 |
Mathias CJ, Welch MJ, Schwartz DB, Spaethe SM, Needleman P. Differentiation in vivo of the sequential blood cell invasion following ureter obstruction of the rabbit kidney. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 16: 25-32. PMID 2714997 DOI: 10.1016/0883-2897(89)90211-0 |
0.145 |
|
| 1973 |
Needleman P, Marshall GR, Douglas JR. Prostaglandin release from vasculature by angiotensin II: dissociation from lipolysis. European Journal of Pharmacology. 23: 316-9. PMID 4355731 DOI: 10.1016/0014-2999(73)90103-9 |
0.145 |
|
| 1977 |
Nishikawa K, Morrison A, Needleman P. Exaggerated prostaglandin biosynthesis and its influence on renal resistance in the isolated hydronephrotic rabbit kidney. The Journal of Clinical Investigation. 59: 1143-50. PMID 864006 DOI: 10.1172/JCI108738 |
0.145 |
|
| 1984 |
Currie MG, Geller DM, Cole BR, Siegel NR, Fok KF, Adams SP, Eubanks SR, Galluppi GR, Needleman P. Purification and sequence analysis of bioactive atrial peptides (atriopeptins). Science (New York, N.Y.). 223: 67-9. PMID 6419347 |
0.144 |
|
| 1984 |
Evers A, Needleman P. Prostaglandin and leukotriene synthesis in normal and infarcted isolated perfused rabbit hearts Federation Proceedings. 43: no. 3786. |
0.143 |
|
| 1975 |
Needleman P, Key SL, Denny SE, Isakson PC, Marshall GR. Mechanism and modification of bradykinin-induced coronary vasodilation. Proceedings of the National Academy of Sciences of the United States of America. 72: 2060-3. PMID 1056012 DOI: 10.1073/pnas.72.6.2060 |
0.142 |
|
| 1988 |
Stockmann PT, Will DH, Sides SD, Brunnert SR, Wilner GD, Leahy KM, Wiegand RC, Needleman P. Reversible induction of right ventricular atriopeptin synthesis in hypertrophy due to hypoxia. Circulation Research. 63: 207-13. PMID 2968194 |
0.141 |
|
| 1984 |
Whiteley PJ, Needleman P. Mechanism of enhanced fibroblast arachidonic acid metabolism by mononuclear cell factor. The Journal of Clinical Investigation. 74: 2249-53. PMID 6439745 DOI: 10.1172/JCI111651 |
0.141 |
|
| 1985 |
Michener ML, Needleman P. The influence of atriopeptin on renal function. Regulatory Peptides. Supplement. 4: 113-7. PMID 2997848 |
0.14 |
|
| 1984 |
Currie MG, Geller DM, Cole BR, Needleman P. Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin cleavage. Proceedings of the National Academy of Sciences of the United States of America. 81: 1230-3. PMID 6230673 |
0.14 |
|
| 1985 |
Hintze TH, Currie MG, Needleman P. Atriopeptins induce selective renal vasodilation in conscious dogs Federation Proceedings. 44: No. 7755. |
0.139 |
|
| 1995 |
Salvemini D, Settle SL, Masferrer JL, Seibert K, Currie MG, Needleman P. Regulation of prostaglandin production by nitric oxide; an in vivo analysis. British Journal of Pharmacology. 114: 1171-8. PMID 7542531 DOI: 10.1111/J.1476-5381.1995.Tb13330.X |
0.139 |
|
| 1982 |
Sheng WY, Wyche A, Lysz T, Needleman P. Prostaglandin endoperoxide E2 isomerase is dissociated from prostaglandin endoperoxide synthetase in the renal cortex. The Journal of Biological Chemistry. 257: 14632-4. PMID 6816794 |
0.139 |
|
| 1983 |
Lysz TW, Needleman P, Ferrendelli JA. Measurement of prostaglandin biosynthetic capacity in discrete areas of the rabbit hippocampal formation. Journal of Neuroscience Research. 10: 317-26. PMID 6580469 DOI: 10.1002/jnr.490100310 |
0.138 |
|
| 1985 |
Lefkowith JB, Needleman P. Anomalous behavior of cardiac and renal arachidonate content in murine essential fatty acid deficiency Federation Proceedings. 44: No. 8247. |
0.138 |
|
| 1985 |
Evers AS, Murphree S, Saffitz JE, Jakschik BA, Needleman P. Effects of endogenously produced leukotrienes, thromboxane, and prostaglandins on coronary vascular resistance in rabbit myocardial infarction. The Journal of Clinical Investigation. 75: 992-9. PMID 3980734 DOI: 10.1172/JCI111801 |
0.137 |
|
| 1983 |
Currie MG, Geller DM, Cole BR, Boylan JG, YuSheng W, Holmberg SW, Needleman P. Bioactive cardiac substances: potent vasorelaxant activity in mammalian atria. Science (New York, N.Y.). 221: 71-3. PMID 6857267 DOI: 10.1126/science.6857267 |
0.136 |
|
| 1976 |
Isakson PC, Raz A, Needleman P. Selective incorporation of 14C-arachidonic acid into the phospholipids of intact tissues and subsequent metabolism to 14C-prostaglandins. Prostaglandins. 12: 739-48. PMID 981699 DOI: 10.1016/0090-6980(76)90049-6 |
0.136 |
|
| 1981 |
Reingold DF, Watters K, Holmberg S, Needleman P. Differential biosynthesis of prostaglandins by hydronephrotic rabbit and cat kidneys. The Journal of Pharmacology and Experimental Therapeutics. 216: 510-5. PMID 7009829 |
0.135 |
|
| 1978 |
Morrison AR, Moritz H, Needleman P. Mechanism of enhanced renal prostaglandin biosynthesis in ureter obstruction. Role of de novo protein synthesis. The Journal of Biological Chemistry. 253: 8210-2. PMID 711747 |
0.135 |
|
| 1980 |
Sivakoff M, Holmberg S, Needleman P. The role of prostaglandins and thromboxane in modulation of perfusion pressure in the hydronephrotic rabbit kidney. Advances in Prostaglandin and Thromboxane Research. 7: 1175-6. PMID 7369027 |
0.134 |
|
| 1990 |
Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. The Journal of Biological Chemistry. 265: 16737-40. PMID 2120205 |
0.133 |
|
| 1985 |
Elliott WJ, Sprecher H, Needleman P. The roles of columbinic and mead acids in rat skin: Morphologic and physiologic studies Federation Proceedings. 44: 3026. |
0.132 |
|
| 1975 |
Needleman P, Marshall GR, Sobel BE. Hormone interactions in the isolated rabbit heart. Synthesis and coronary vasomotor effects of prostaglandins, angiotensin, and bradykinin. Circulation Research. 37: 802-8. PMID 1192572 DOI: 10.1161/01.Res.37.6.802 |
0.131 |
|
| 1972 |
Needleman P, Freer RJ, Marshall GR. Angiotensin-receptor interaction: influence of pH on angiotensin inhibition by Phe 4 -Tyr 8 -angiotensin II in rat uterine smooth muscle. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 200: 118-25. PMID 4345266 |
0.131 |
|
| 1984 |
Currie MG, Geller DM, Chao J, Margolius HS, Needleman P. Kallikrein activation of a high molecular weight atrial peptide. Biochemical and Biophysical Research Communications. 120: 461-6. PMID 6203521 DOI: 10.1016/0006-291X(84)91276-2 |
0.13 |
|
| 1975 |
Turk J, Needleman P, Marshall GR. Alkylating analogs of bradykinin. Journal of Medicinal Chemistry. 18: 1135-9. PMID 240938 DOI: 10.1002/Chin.197608334 |
0.13 |
|
| 1975 |
Turk J, Needleman P, Marshall GR. Analogs of bradykinin with restricted conformational freedom. Journal of Medicinal Chemistry. 18: 1139-42. PMID 1236952 DOI: 10.1002/Chin.197608333 |
0.129 |
|
| 1977 |
Hsueh W, Isakson PC, Needleman P. Hormone selective lipase activation in the isolated rabbit heart. Prostaglandins. 13: 1073-91. PMID 887798 |
0.128 |
|
| 1982 |
Lysz TW, Needleman P. Evidence for two distinct forms of fatty acid cyclooxygenase in brain. Journal of Neurochemistry. 38: 1111-7. PMID 6801204 |
0.128 |
|
| 1993 |
Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proceedings of the National Academy of Sciences of the United States of America. 90: 7240-4. PMID 7688473 DOI: 10.1073/Pnas.90.15.7240 |
0.127 |
|
| 1976 |
Blumberg A, Denny S, Nishikawa K, Pure E, Marshall GR, Needleman P. Angiotensin III-induced prostaglandin (PG) release. Prostaglandins. 11: 195-7. PMID 1257496 DOI: 10.1016/0090-6980(76)90184-2 |
0.125 |
|
| 1985 |
Elliott WJ, Morrison AR, Sprecher HW, Needleman P. The metabolic transformations of columbinic acid and the effect of topical application of the major metabolites on rat skin. The Journal of Biological Chemistry. 260: 987-92. PMID 3918037 |
0.124 |
|
| 1992 |
Greenwald JE, Needleman P, Siegel N, Tetens E, Biel B, Ritter D. Processing of atriopeptin prohormone by nonmyocytic atrial cells. Biochemical and Biophysical Research Communications. 188: 644-54. PMID 1445310 DOI: 10.1016/0006-291X(92)91105-Y |
0.124 |
|
| 1979 |
Needleman P, Wyche A, Raz A. Platelet and blood vessel arachidonate metabolism and interactions. The Journal of Clinical Investigation. 63: 345-9. PMID 372240 DOI: 10.1172/JCI109309 |
0.122 |
|
| 1984 |
McCluskey ER, Kramer JB, Corr PB, Needleman P. In vivo inhibition of thromboxane synthetase in infarcted canine myocardium. Biochemical and Biophysical Research Communications. 121: 552-7. PMID 6539597 DOI: 10.1016/0006-291X(84)90217-1 |
0.122 |
|
| 1976 |
Needleman P. The synthesis and function of prostaglandins in the heart. Federation Proceedings. 35: 2376-81. PMID 786741 |
0.121 |
|
| 1986 |
Needleman P, Greenwald JE. Atriopeptin: a cardiac hormone intimately involved in fluid, electrolyte, and blood-pressure homeostasis. The New England Journal of Medicine. 314: 828-34. PMID 2936957 DOI: 10.1056/NEJM198603273141306 |
0.121 |
|
| 1989 |
Freed MS, Spaethe SM, Lefkowith JB, Saffitz JE, Needleman P. Essential fatty acid deficiency inhibits early but not late leukocyte infiltration in rabbit myocardial infarcts. Prostaglandins. 38: 33-44. PMID 2546188 DOI: 10.1016/0090-6980(89)90014-2 |
0.12 |
|
| 1984 |
Evers A, Needleman P. ENDOGENOUSLY PRODUCED LEUKOTRIENES CAUSE VASOCONSTRICTION IN INFARCTED RABBIT HEARTS Anesthesiology. 61: A88-A88. DOI: 10.1097/00000542-198409001-00088 |
0.119 |
|
| 1984 |
Geller DM, Currie MG, Siegel NR, Fok KF, Adams SP, Needleman P. The sequence of an atriopeptigen: a precursor of the bioactive atrial peptides. Biochemical and Biophysical Research Communications. 121: 802-7. PMID 6547606 DOI: 10.1016/0006-291X(84)90749-6 |
0.118 |
|
| 1984 |
Oshima T, McCluskey ER, Honda A, Needleman P. Pharmacological manipulation of canine cyclooxygenase and thromboxane synthetase in vivo: differential renal and platelet recovery rates. The Journal of Pharmacology and Experimental Therapeutics. 229: 598-602. PMID 6425495 |
0.117 |
|
| 1985 |
Kramer JB, Davis AG, Dean R, McCluskey ER, Needleman P, Corr PB. Thromboxane A2 does not contribute to arrhythmogenesis during evolving canine myocardial infarction. Journal of Cardiovascular Pharmacology. 7: 1069-76. PMID 2418290 |
0.117 |
|
| 1982 |
McCluskey ER, Corr PB, Lee BI, Saffitz JE, Needleman P. The arachidonic acid metabolic capacity of canine myocardium is increased during healing of acute myocardial infarction. Circulation Research. 51: 743-50. PMID 7139887 |
0.117 |
|
| 1992 |
Masferrer JL, Seibert K, Zweifel B, Needleman P. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme. Proceedings of the National Academy of Sciences of the United States of America. 89: 3917-21. PMID 1570314 |
0.116 |
|
| 1985 |
Elliott WJ, Sprecher H, Needleman P. Physiologic effects of columbinic acid and its metabolites on rat skin. Biochimica Et Biophysica Acta. 835: 158-60. PMID 3924106 DOI: 10.1016/0005-2760(85)90043-8 |
0.115 |
|
| 2002 |
Levin G, Duffin KL, Obukowicz MG, Hummert SL, Fujiwara H, Needleman P, Raz A. Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2. The Biochemical Journal. 365: 489-96. PMID 11939906 DOI: 10.1042/BJ20011798 |
0.115 |
|
| 1987 |
McLaughlin LL, Wei YF, Stockmann PT, Leahy KM, Needleman P, Grassi J, Pradelles P. Development, validation and application of an enzyme immunoassay (EIA) of atriopeptin. Biochemical and Biophysical Research Communications. 144: 469-76. PMID 2953338 DOI: 10.1016/S0006-291X(87)80533-8 |
0.114 |
|
| 1982 |
Sprecher H, VanRollins M, Sun F, Wyche A, Needleman P. Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney. The Journal of Biological Chemistry. 257: 3912-8. PMID 6801054 |
0.114 |
|
| 1985 |
Evers A, Needleman P. Prostaglandin and leukotriene synthesis in rabbit cardiac atria Federation Proceedings. 44: No. 8248. |
0.113 |
|
| 1985 |
Tripp CS, Mahoney M, Needleman P. Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase. The Journal of Biological Chemistry. 260: 5895-8. PMID 3922966 |
0.113 |
|
| 1989 |
Spaethe SM, Hsueh W, Needleman P. Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF antagonist L-659,989. The Journal of Pharmacology and Experimental Therapeutics. 248: 1308-16. PMID 2539462 |
0.112 |
|
| 1987 |
Hsieh KH, Needleman P, Marshall GR. Long-acting angiotensin II inhibitors containing hexafluorovaline in position 8. Journal of Medicinal Chemistry. 30: 1097-100. PMID 3585907 DOI: 10.1021/Jm00389A021 |
0.111 |
|
| 1984 |
Jonas PE, Leahy KM, DeSchryver-Kecskemeti K, Needleman P. Cellular interactions and exaggerated arachidonic acid metabolism in rabbit renal injury. Journal of Leukocyte Biology. 35: 55-64. PMID 6423746 |
0.111 |
|
| 1985 |
Griffin AC, Evers A, Jakschik BA, Needleman P. Leukotriene and prostaglandin production in the rabbit hydronephrotic kidney Federation Proceedings. 44: No. 8249. |
0.109 |
|
| 1985 |
Bloch MH, McLaughlin LL, Crowley J, Needleman P, Morrison AR. Arachidonic acid metabolic pathway of the rabbit placenta. Prostaglandins. 29: 203-16. PMID 3920728 DOI: 10.1016/0090-6980(85)90202-3 |
0.109 |
|
| 1984 |
Wakitani K, Currie RG, Geller DM, Needleman P. The influence of selective proteolytic cleavage of atrial peptides upon their biological activity Federation Proceedings. 43: no. 994. |
0.109 |
|
| 1995 |
Salvemini D, Manning PT, Zweifel BS, Seibert K, Connor J, Currie MG, Needleman P, Masferrer JL. Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. The Journal of Clinical Investigation. 96: 301-8. PMID 7542281 DOI: 10.1172/Jci118035 |
0.108 |
|
| 1988 |
Raz A, Wyche A, Siegel N, Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1. The Journal of Biological Chemistry. 263: 3022-8. PMID 3125173 |
0.106 |
|
| 1986 |
Tripp CS, Wyche A, Unanue ER, Needleman P. The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro. Journal of Immunology (Baltimore, Md. : 1950). 137: 3915-20. PMID 3097136 |
0.105 |
|
| 1994 |
Masferrer JL, Reddy ST, Zweifel BS, Seibert K, Needleman P, Gilbert RS, Herschman HR. In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages. The Journal of Pharmacology and Experimental Therapeutics. 270: 1340-4. PMID 7932188 |
0.105 |
|
| 1985 |
Cole BR, Needleman P. Atriopeptins: volume regulatory hormones. Clinical Research. 33: 389-94. PMID 2931233 |
0.104 |
|
| 1978 |
Morrison AR, Nishikawa K, Needleman P. Thromboxane A2 biosynthesis in the ureter obstructed isolated perfused kidney of the rabbit. The Journal of Pharmacology and Experimental Therapeutics. 205: 1-8. PMID 633076 |
0.103 |
|
| 1983 |
Currie MG, Cole BR, DeSchryver-Kecskemeti K, Holmberg S, Needleman P. Cell culture of renal epithelium derived from rabbit microdissected cortical collecting tubules. The American Journal of Physiology. 244: F724-8. PMID 6305209 |
0.103 |
|
| 1979 |
Sivakoff M, Pure E, Hsueh W, Needleman P. Prostaglandins and the heart. Federation Proceedings. 38: 78-82. PMID 103755 |
0.102 |
|
| 1979 |
Hsueh W, Kuhn C, Needleman P. Relationship of prostaglandin secretion by rabbit alveolar macrophages to phagocytosis and lysosomal enzyme release. The Biochemical Journal. 184: 345-54. PMID 534533 |
0.102 |
|
| 1976 |
Needleman P. Organic nitrate metabolism. Annual Review of Pharmacology and Toxicology. 16: 81-93. PMID 820240 DOI: 10.1146/annurev.pa.16.040176.000501 |
0.101 |
|
| 1985 |
Albrightson CR, Baenziger NL, Needleman P. Exaggerated human vascular cell prostaglandin biosynthesis mediated by monocytes: role of monokines and interleukin 1. Journal of Immunology (Baltimore, Md. : 1950). 135: 1872-7. PMID 3874907 |
0.1 |
|
| 1989 |
Raz A, Wyche A, Needleman P. Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases. Proceedings of the National Academy of Sciences of the United States of America. 86: 1657-61. PMID 2493647 |
0.1 |
|
| 1987 |
Lefkowith JB, Jakschik BA, Stahl P, Needleman P. Metabolic and functional alterations in macrophages induced by essential fatty acid deficiency. The Journal of Biological Chemistry. 262: 6668-75. PMID 3571276 |
0.099 |
|
| 1976 |
Moncada S, Needleman P, Bunting S, Vane JR. Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. Prostaglandins. 12: 323-35. PMID 968048 DOI: 10.1016/0090-6980(76)90014-9 |
0.099 |
|
| 1990 |
Masferrer JL, Zweifel BS, Seibert K, Needleman P. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. The Journal of Clinical Investigation. 86: 1375-9. PMID 2120289 DOI: 10.1172/JCI114850 |
0.099 |
|
| 1986 |
Lefkowith JB, Evers AS, Elliott WJ, Needleman P. Essential fatty acid deficiency: a new look at an old problem. Prostaglandins, Leukotrienes, and Medicine. 23: 123-7. PMID 3020581 DOI: 10.1016/0262-1746(86)90174-5 |
0.097 |
|
| 1986 |
Tripp CS, Unanue ER, Needleman P. Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response. Proceedings of the National Academy of Sciences of the United States of America. 83: 9655-9. PMID 3099288 |
0.097 |
|
| 1983 |
Pohlman T, Yates J, Needleman P, Klahr S. Effects of prostacyclin on short-circuit current and water flow in the toad urinary bladder. The American Journal of Physiology. 244: F270-7. PMID 6187221 |
0.096 |
|
| 1978 |
Isakson PC, Raz A, Hsueh W, Needleman P. Lipases and prostaglandin biosynthesis. Advances in Prostaglandin and Thromboxane Research. 3: 113-20. PMID 655002 |
0.095 |
|
| 1987 |
Stockmann PT, Needleman P. Induction of ventricular atriopeptin synthesis in aortocaval fistula Surgical Forum. 38: 251-253. |
0.095 |
|
| 1982 |
Bloch MH, McLaughlin L, Needleman P. Arachidonic acid metabolism of rabbit placenta Federation Proceedings. 41: No. 8470. |
0.094 |
|
| 1986 |
Needleman P. Physiology. The expanding physiological roles of atrial natriuretic factor. Nature. 321: 199-200. PMID 3012350 DOI: 10.1038/321199a0 |
0.092 |
|
| 1984 |
Morrison AR, McLaughlin L, Bloch M, Needleman P. A novel cyclooxygenase metabolite of arachidonic acid. The Journal of Biological Chemistry. 259: 13579-83. PMID 6436248 |
0.092 |
|
| 1977 |
Minkes M, Stanford N, Chi MM, Roth GJ, Raz A, Needleman P, Majerus PW. Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions. The Journal of Clinical Investigation. 59: 449-54. PMID 190267 DOI: 10.1172/Jci108659 |
0.092 |
|
| 1985 |
Tripp CS, Leahy KM, Needleman P. Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages. The Journal of Clinical Investigation. 76: 898-901. PMID 3928686 DOI: 10.1172/JCI112051 |
0.092 |
|
| 1976 |
Needleman P, Marshall GR. Angiotensin antagonists: overview and projection. Federation Proceedings. 35: 2486-7. PMID 185092 |
0.092 |
|
| 1969 |
Needleman P, Blehm DJ, Rotskoff KS. Relationship between glutathione-dependent dentration and the vasodilator effectiveness of organic nitrates. The Journal of Pharmacology and Experimental Therapeutics. 165: 286-8. PMID 4973991 |
0.091 |
|
| 1998 |
Obukowicz MG, Welsch DJ, Salsgiver WJ, Martin-Berger CL, Chinn KS, Duffin KL, Raz A, Needleman P. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. The Journal of Pharmacology and Experimental Therapeutics. 287: 157-66. PMID 9765335 |
0.091 |
|
| 1976 |
Needleman P, Moncada S, Bunting S, Vane JR, Hamberg M, Samuelsson B. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature. 261: 558-60. PMID 934294 DOI: 10.1038/261558A0 |
0.091 |
|
| 1990 |
Honda A, Raz A, Needleman P. Induction of cyclo-oxygenase synthesis in human promyelocytic leukaemia (HL-60) cells during monocytic or granulocytic differentiation. The Biochemical Journal. 272: 259-62. PMID 2176083 |
0.09 |
|
| 1989 |
Raz A, Wyche A, Fagan D, Needleman P. The cell biology of fibroblast cyclooxygenase. Advances in Experimental Medicine and Biology. 259: 1-21. PMID 2516411 |
0.09 |
|
| 1980 |
Needleman P, Whitaker MO, Wyche A, Watters K, Sprecher H, Raz A. Manipulation of platelet aggregation by prostaglandins and their fatty acid precursors: pharmacological basis for a therapeutic approach. Prostaglandins. 19: 165-81. PMID 6247744 DOI: 10.1016/0090-6980(80)90163-X |
0.089 |
|
| 1978 |
Needleman P, Kaley G. Cardiac and coronary prostaglandin synthesis and function. The New England Journal of Medicine. 298: 1122-8. PMID 347299 DOI: 10.1056/NEJM197805182982005 |
0.089 |
|
| 1986 |
Needleman P, Turk J, Jakschik BA, Morrison AR, Lefkowith JB. Arachidonic acid metabolism. Annual Review of Biochemistry. 55: 69-102. PMID 3017195 DOI: 10.1146/annurev.bi.55.070186.000441 |
0.088 |
|
| 1977 |
Morrison AR, Nishikawa K, Needleman P. Unmasking of thromboxane A2 synthesis by ureteral obstruction in the rabbit kidney. Nature. 267: 259-60. PMID 865616 |
0.087 |
|
| 1984 |
Jonas PE, Needleman P. Monocyte factor modulates fibroblast arachidonic acid metabolism Federation Proceedings. 43: no. 4408. |
0.087 |
|
| 1986 |
Elliott WJ, Morrison AR, Sprecher H, Needleman P. Calcium-dependent oxidation of 5,8,11-icosatrienoic acid by the cyclooxygenase enzyme system. The Journal of Biological Chemistry. 261: 6719-24. PMID 3084488 |
0.085 |
|
| 1992 |
Beckerman KP, Schreiber RD, Needleman P. Cytokine modulation of immune activation associated suppression of macrophage cyclooxygenase activity in vivo. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 47: 231-8. PMID 1475281 DOI: 10.1016/0952-3278(92)90245-E |
0.084 |
|
| 1984 |
Elliott WJ, McLaughlin LL, Bloch MH, Needleman P. Arachidonic acid metabolism by rabbit fetal membranes of various gestational ages. Prostaglandins. 27: 27-36. PMID 6424180 DOI: 10.1016/0090-6980(84)90218-1 |
0.084 |
|
| 1975 |
Needleman P, Key SL, Isakson PC, Kulkarni PS. Relationship between oxygen tension, coronary vasodilation and prostaglandin biosynthesis in the isolated rabbit heart. Prostaglandins. 9: 123-34. PMID 1135423 |
0.083 |
|
| 1984 |
Cole BR, Boylan JG, Kuhnline MA, Currie MG, Geller DM, Needleman P. ATRIOPEPTINS: NATRIURESIS OCCURS INDEPENDENT OF VASCULAR EFFECTS Pediatric Research. 18: 359A-359A. DOI: 10.1203/00006450-198404001-01599 |
0.083 |
|
| 1973 |
Needleman P, Marshall GR, Rivier J. Angiotensin II. Synthesis and biological activity of 6-(1-methylhistidine) and 6-(3-methylhistidine) analogs. Journal of Medicinal Chemistry. 16: 968-70. PMID 4355510 DOI: 10.1021/Jm00267A002 |
0.082 |
|
| 1998 |
Obukowicz MG, Raz A, Pyla PD, Rico JG, Wendling JM, Needleman P. Identification and characterization of a novel delta6/delta5 fatty acid desaturase inhibitor as a potential anti-inflammatory agent. Biochemical Pharmacology. 55: 1045-58. PMID 9605428 DOI: 10.1016/S0006-2952(97)00665-5 |
0.082 |
|
| 1973 |
Jakschik B, Needleman P. Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase. Biochemical and Biophysical Research Communications. 53: 539-44. PMID 4197820 |
0.082 |
|
| 1987 |
Tripp CS, Needleman P. Regulation of macrophage arachidonic acid metabolism during the immune response. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 17: 1085-90. PMID 2960149 |
0.079 |
|
| 1987 |
Pentland AP, George J, Moran C, Needleman P. Cellular confluence determines injury-induced prostaglandin E2 synthesis by human keratinocyte cultures. Biochimica Et Biophysica Acta. 919: 71-8. PMID 2436667 DOI: 10.1016/0005-2760(87)90219-0 |
0.079 |
|
| 1985 |
Needleman P, Wyche A, Sprecher H, Elliott WJ, Evers A. A unique cardiac cytosolic acyltransferase with preferential selectivity for fatty acids that form cyclooxygenase/lipoxygenase metabolites and reverse essential fatty acid deficiency. Biochimica Et Biophysica Acta. 836: 267-73. PMID 3927984 DOI: 10.1016/0005-2760(85)90075-X |
0.078 |
|
| 1986 |
Pentland AP, Needleman P. Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis. The Journal of Clinical Investigation. 77: 246-51. PMID 3080474 DOI: 10.1172/Jci112283 |
0.077 |
|
| 1988 |
Merlie JP, Fagan D, Mudd J, Needleman P. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). The Journal of Biological Chemistry. 263: 3550-3. PMID 2831188 |
0.077 |
|
| 1984 |
Elliott WJ, Needleman P. The metabolism of columbinic acid by sheep vesicular microsomes and human platelets Federation Proceedings. 43: no. 3783. |
0.077 |
|
| 1982 |
Sams AR, Sprecher H, Sankarappa SK, Needleman P. Selective inhibitors of platelet arachidonic acid metabolism: aggregation independent of lipoxygenase. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 9: 19-28. PMID 6211951 |
0.077 |
|
| 1990 |
Raz A, Wyche A, Fu J, Seibert K, Needleman P. Regulation of prostanoids synthesis in human fibroblasts and human blood monocytes by interleukin-1, endotoxin, and glucocorticoids. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 20: 22-7. PMID 2144696 |
0.076 |
|
| 1980 |
LeDuc LE, Needleman P. Prostaglandin synthesis by dog gastrointestinal tract. Advances in Prostaglandin and Thromboxane Research. 8: 1515-7. PMID 6769317 |
0.076 |
|
| 1978 |
Needleman P. Characterization of the reaction sequence involved in phospholipid labeling and deacylation and prostaglandin synthesis and actions. The Journal of Allergy and Clinical Immunology. 62: 96-102. PMID 97337 |
0.076 |
|
| 1985 |
McCluskey ER, Murphree S, Saffitz JE, Morrison AR, Needleman P. Temporal changes in 12-HETE formation in two models of canine myocardial infarction. Prostaglandins. 29: 387-403. PMID 3923561 DOI: 10.1016/0090-6980(85)90098-X |
0.074 |
|
| 1977 |
Raz A, Isakson PC, Minkes MS, Needleman P. Characterization of a novel metabolic pathway of arachidonate in coronary arteries which generates a potent endogenous coronary vasodilator. The Journal of Biological Chemistry. 252: 1123-6. PMID 838699 |
0.074 |
|
| 1976 |
Bunting S, Moncada S, Needleman P, Vane JR. Proceedings: Formation of prostaglandin endoperoxides and rabbit aorta contracting substance (RCS) by coupling two enzyme systems. British Journal of Pharmacology. 56: 344P-345P. PMID 944058 |
0.074 |
|
| 1977 |
Moncada S, Bunting S, Mullane K, Thorogood P, Vane JR, Raz A, Needleman P. Imidazole: a selective inhibitor of thromboxane synthetase. Prostaglandins. 13: 611-8. PMID 558637 DOI: 10.1016/0090-6980(77)90232-5 |
0.073 |
|
| 1977 |
Needleman P, Bryan B, Wyche A, Bronson SD, Eakins K, Ferrendelli JA, Minkes M. Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions. Prostaglandins. 14: 897-907. PMID 594391 |
0.073 |
|
| 1977 |
Needleman P, Raz A, Ferrendelli JA, Minkes M. Application of imidazole as a selective inhibitor thromboxane synthetase in human platelets. Proceedings of the National Academy of Sciences of the United States of America. 74: 1716-20. PMID 193113 |
0.073 |
|
| 1984 |
Honda A, Morrison AR, McCluskey ER, Needleman P. Arachidonic acid metabolic pathways in the rabbit pericardium. Biochimica Et Biophysica Acta. 794: 403-10. PMID 6430346 DOI: 10.1016/0005-2760(84)90006-7 |
0.072 |
|
| 1981 |
LeDuc LE, Wyche AA, Sprecher H, Sankarappe SK, Needleman P. Analogues of arachidonic acid used to evaluate structural determinants of prostaglandin receptor and enzyme specificities. Molecular Pharmacology. 19: 242-7. PMID 6262618 |
0.072 |
|
| 1965 |
Needleman P, Krantz JC. The biotransformation of nitroglycerin. Biochemical Pharmacology. 14: 1225-30. PMID 4955308 |
0.071 |
|
| 1976 |
Kulkarni PS, Roberts R, Needleman P. Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate. Prostaglandins. 12: 337-53. PMID 968049 |
0.07 |
|
| 1976 |
Turk J, Needleman P, Marshall GR. Analogues of angiotensin II with restricted conformational freedom, including a new antagonist. Molecular Pharmacology. 12: 217-24. PMID 1264066 |
0.07 |
|
| 2001 |
Duffin KL, Obukowicz MG, Salsgiver WJ, Welsch DJ, Shieh C, Raz A, Needleman P. Lipid remodeling in mouse liver and plasma resulting from delta6 fatty acid desaturase inhibition. Lipids. 36: 1203-8. PMID 11795852 |
0.069 |
|
| 1981 |
Needleman P, Wyche A, LeDuc L, Sankarappe SK, Jakschik BA, Sprecher H. Fatty acids as sources of potential "magic bullets" for the modification of platelet and vascular function. Progress in Lipid Research. 20: 415-22. PMID 6804971 |
0.069 |
|
| 1970 |
Needleman P, Blehm DJ. Effect of epinephrine and potassium chloride on contraction and energy intermediates in rabbit thoracic aorta strips. Life Sciences. Pt. 1: Physiology and Pharmacology. 9: 1181-9. PMID 5481741 |
0.069 |
|
| 1985 |
Albrightson C, Baenziger N, Needleman P. Mononuclear cell factor and interleukin-1 (IL-1) alter endothelial cell prostaglandin (PG) synthesis, proliferation and morphology Federation Proceedings. 44: No. 8246. |
0.068 |
|
| 1988 |
Tripp CS, Needleman P, Kassab JT, Weinstock JV. Macrophages isolated from liver granulomas of murine Schistosoma mansoni synthesize predominantly TxA2 during the acute and chronic phases of infection. Journal of Immunology (Baltimore, Md. : 1950). 140: 3140-3. PMID 3129511 |
0.068 |
|
| 1983 |
Elliott WJ, Needleman P, Sprecher H. Stereospecific synthesis of columbinic acid Journal of Organic Chemistry. 48: 5378-5379. |
0.068 |
|
| 1979 |
Needleman P, Raz A, Minkes MS, Ferrendelli JA, Sprecher H. Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties. Proceedings of the National Academy of Sciences of the United States of America. 76: 944-8. PMID 218223 |
0.068 |
|
| 1990 |
Raz A, Needleman P. Differential modification of cyclo-oxygenase and peroxidase activities of prostaglandin endoperoxidase synthase by proteolytic digestion and hydroperoxides. The Biochemical Journal. 269: 603-7. PMID 2117918 |
0.067 |
|
| 1991 |
Seibert K, Masferrer JL, FU JY, Honda A, Raz A, Needleman P. The biochemical and pharmacological manipulation of cellular cyclooxygenase (COX) activity. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 21: 45-51. PMID 1825580 |
0.065 |
|
| 1970 |
Needleman P. Tolerance to the vascular effects of glyceryl trinitrate. The Journal of Pharmacology and Experimental Therapeutics. 171: 98-102. PMID 4983392 |
0.064 |
|
| 1979 |
LeDuc LE, Needleman P. Regional localization of prostacyclin and thromboxane synthesis in dog stomach and intestinal tract. The Journal of Pharmacology and Experimental Therapeutics. 211: 181-8. PMID 385829 |
0.064 |
|
| 1985 |
Albrightson CR, Baenziger NL, Needleman P. A mononuclear cell factor is a potent agonist of prostaglandin biosynthesis in cultured human fibroblasts and smooth muscle and endothelial cells. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 15: 213-6. PMID 2936096 |
0.062 |
|
| 1980 |
Fried J, Barton J, Kittisopikul S, Needleman P, Wyche A. Synthesis and biological properties of selective inhibitors of the prostaglandin cascade. Advances in Prostaglandin and Thromboxane Research. 6: 427-36. PMID 6770604 |
0.062 |
|
| 1977 |
Needleman P, Kulkarni PS, Raz A. Coronary tone modulation: formation and actions of prostaglandins, endoperoxides, and thromboxanes. Science (New York, N.Y.). 195: 409-12. PMID 831285 |
0.061 |
|
| 1985 |
Pentland A, Needleman P. Modulation of proliferation in non-confluent keratinocyte cultures by endogenous prostaglandin (PG) synthesis Federation Proceedings. 44: No. 8251. |
0.061 |
|
| 1999 |
Seibert K, Lefkowith J, Tripp C, Isakson P, Needleman P. COX-2 inhibitors--is there cause for concern? Nature Medicine. 5: 621-2. PMID 10371498 DOI: 10.1038/9465 |
0.061 |
|
| 1966 |
Needleman P, Hunter FE. Effects of organic nitrates on mitochondrial respiration and swelling: possible correlations with the mechanism of pharmacologic action. Molecular Pharmacology. 2: 134-43. PMID 5905663 |
0.061 |
|
| 1980 |
Whitaker MO, Needleman P, Wyche A, Fitzpatrick FA, Sprecher H. PGD3 is the mediator of the antiaggregatory effects of the trienoic endoperoxide PGH3. Advances in Prostaglandin and Thromboxane Research. 6: 301-3. PMID 6966885 |
0.06 |
|
| 1973 |
Vine WH, Brueckner DA, Needleman P, Marshall GR. Synthesis, biological activity, and 19 F nuclear magnetic resonance spectra of angiotensin II analogs containing fluorine. Biochemistry. 12: 1630-7. PMID 4349406 DOI: 10.1021/Bi00732A026 |
0.059 |
|
| 1992 |
Needleman PD, Westall G. Demutualisation of a United Kingdom Mutual Life Insurance Company Transactions of the Faculty of Actuaries. 43: 278-375. DOI: 10.1017/S0071368600010090 |
0.058 |
|
| 1991 |
Needleman PD, Westall G. Demutualisation of a United Kingdom mutual life insurance company Journal of the Institute of Actuaries. 118: 321-399. DOI: 10.1017/S0020268100019491 |
0.058 |
|
| 1987 |
Tripp CS, Needleman P, Unanue ER. Indomethacin in vivo increases the sensitivity to Listeria infection in mice. A possible role for macrophage thromboxane A2 synthesis. The Journal of Clinical Investigation. 79: 399-403. PMID 3468120 DOI: 10.1172/JCI112825 |
0.056 |
|
| 1980 |
Needleman P, Sprecher H, Whitaker MO, Wyche A. Mechanism underlying the inhibition of platelet aggregation by eicosapentaenoic acid and its metabolites. Advances in Prostaglandin and Thromboxane Research. 6: 61-8. PMID 6247894 |
0.056 |
|
| 1979 |
Weiss SJ, Turk J, Needleman P. A mechanism for the hydroperoxide-mediated inactivation of prostacyclin synthetase. Blood. 53: 1191-6. PMID 376000 |
0.056 |
|
| 1984 |
Albrightson CR, Baenzinger NL, Needleman P. The effects of mononuclear cell factors on prostacyclin production and thymidine incorporation in cultured endothelial and smooth muscle cells Federation Proceedings. 43: no. 3792. |
0.055 |
|
| 1979 |
Whitaker MO, Wyche A, Fitzpatrick F, Sprecher H, Needleman P. Triene prostaglandins: prostaglandin D3 and icosapentaenoic acid as potential antithrombotic substances. Proceedings of the National Academy of Sciences of the United States of America. 76: 5919-23. PMID 230492 |
0.055 |
|
| 1979 |
Minkes MS, Joist JH, Needleman P. Arachidonic acid-induced platelet aggregation independent of ADP-release in a patient with a bleeding disorder due to platelet storage pool disease. Thrombosis Research. 15: 169-79. PMID 384595 |
0.054 |
|
| 1997 |
Needleman P, Isakson PC. The discovery and function of COX-2. The Journal of Rheumatology. Supplement. 49: 6-8. PMID 9249644 |
0.053 |
|
| 1979 |
Needleman P. Prostacyclin in blood vessel-platelet interactions: perspectives and questions. Nature. 279: 14-5. PMID 377090 |
0.053 |
|
| 1980 |
Turk J, Wyche A, Needleman P. Inactivation of vascular prostacyclin synthetase by platelet lipoxygenase products. Biochemical and Biophysical Research Communications. 95: 1628-34. PMID 6774728 |
0.053 |
|
| 1981 |
Needleman P, Holmberg S, Mandelbaum B. Ductus arteriosus closure may result from suppression of prostacyclin synthetase by an intrinsic hydroperoxy fatty acid. Prostaglandins. 22: 675-82. PMID 7034055 |
0.053 |
|
| 1984 |
Schwartz D, Mathias C, Welch M, Needleman P. Indium labelled leukocytes as markers of inflammatory cellular changes in hydronephrosis Federation Proceedings. 43: no. 4414. |
0.052 |
|
| 1986 |
Lefkowith JB, Sprecher H, Needleman P. The role and manipulation of eicosanoids in essential fatty acid deficiency. Progress in Lipid Research. 25: 111-7. PMID 3423088 DOI: 10.1016/0163-7827(86)90024-X |
0.052 |
|
| 1965 |
Needleman P, Hunter FE. The transformation of glyceryl trinitrate and other nitrates by glutathione-organic nitrate reductase. Molecular Pharmacology. 1: 77-86. PMID 4378648 |
0.049 |
|
| 1976 |
Needleman P, Minkes M, Raz A. Thromboxanes: selective biosynthesis and distinct biological properties. Science (New York, N.Y.). 193: 163-5. PMID 945611 |
0.047 |
|
| 1980 |
Schonfeld G, Pfleger B, Needleman P, Kipnis D. Indomethacin inhibits the cellular receptor-dependent processing of low density lipoproteins; cyclic nucleotides have no effect. The Journal of Clinical Endocrinology and Metabolism. 51: 662-8. PMID 7410542 DOI: 10.1210/jcem-51-3-662 |
0.047 |
|
| 1995 |
Salvemini D, Seibert K, Masferrer JL, Settle SL, Currie MG, Needleman P. Nitric Oxide Activates the Cyclooxygenase Pathway in Inflammation. American Journal of Therapeutics. 2: 616-619. PMID 11854836 DOI: 10.1097/00045391-199509000-00007 |
0.046 |
|
| 1976 |
Needleman P. Letter: Efficacy of long-acting nitrates. I. sublingual versus oral administration. The American Journal of Cardiology. 38: 400-2. PMID 961615 DOI: 10.1016/0002-9149(76)90188-0 |
0.044 |
|
| 1999 |
Needleman P, Manning PT. Interactions between the inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) pathways: implications for therapeutic intervention in osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 7: 367-70. PMID 10419769 DOI: 10.1053/joca.1998.0237 |
0.043 |
|
| 1995 |
Salvemini D, Seibert K, Masferrer JL, Settle SL, Misko TP, Currie MG, Needleman P. Nitric oxide and the cyclooxygenase pathway. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 491-3. PMID 7537440 |
0.042 |
|
| 1980 |
Jakschik BA, Sams AR, Sprecher H, Needleman P. Fatty acid structural requirements for leukotriene biosynthesis. Prostaglandins. 20: 401-10. PMID 6106262 |
0.04 |
|
| 1995 |
Needleman P, Roff T. Asset Shares and their Use in the Financial Management of a With-Profits Fund British Actuarial Journal. 1: 603-688. DOI: 10.1017/S1357321700001276 |
0.04 |
|
| 1999 |
Hairs C, Arnold M, Gustar A, Hare D, Needleman P, Tuley P, Webber J. The Closed Fund Alternative British Actuarial Journal. 5: 699-761. DOI: 10.1017/S1357321700000647 |
0.04 |
|
| 1962 |
NEEDLEMAN P. Potentiation by phenobarbital of the diuretic response to chlorothiazide. American Journal of Pharmacy and the Sciences Supporting Public Health. 134: 205-8. PMID 14478745 |
0.04 |
|
| 1978 |
Needleman P. Experimental criteria for evaluating prostaglandin biosynthesis and intrinsic function. Biochemical Pharmacology. 27: 1515-8. PMID 100118 |
0.039 |
|
| 1989 |
Fagan D, Merlie J, Siegel N, Raz A, Mudd J, Needleman P. Complementary DNA clone for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 19: 42-8. PMID 2526509 |
0.039 |
|
| 1999 |
Obukowicz M, Welsch D, Salsgiver W, Martin-Berger C, Chinn K, Duffin K, Raz A, Needleman P. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. Lipids. 34: S149. PMID 10419129 DOI: 10.1007/BF02562269 |
0.035 |
|
| 1996 |
Scott P, Elliott S, Gray L, Hewitson T, Lechmere D, Lewis D, Needleman P. An Alternative to the Net Premium Valuation Method for Statutory Reporting British Actuarial Journal. 2: 527-621. DOI: 10.1017/S1357321700003500 |
0.033 |
|
| 1961 |
NEEDLEMAN P. Current concepts of the mode of action of salicylates in rheumatic diseases. American Journal of Pharmacy and the Sciences Supporting Public Health. 133: 219-25. PMID 13728108 |
0.029 |
|
| 1978 |
LeDuc LE, Marshall GR, Needleman P. Differentiation of bradykinin receptors and of kininases with conformational analogues of bradykinin. Molecular Pharmacology. 14: 413-21. PMID 207969 |
0.029 |
|
| 1985 |
Tripp CS, Leahy K, Needleman P. Selective conservation of macrophage TxA2 synthase activity during the immune response Federation Proceedings. 44: No. 8250. |
0.027 |
|
| 1981 |
Reingold DF, Kawasaki A, Needleman P. A novel prostaglandin 11-keto reductase found in rabbit liver. Biochimica Et Biophysica Acta. 659: 179-88. PMID 7248318 |
0.027 |
|
| 2000 |
Masferrer JL, Needleman P. Anti-inflammatories for cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 12400-1. PMID 11058172 DOI: 10.1073/pnas.240459597 |
0.025 |
|
| 2002 |
Shelley M, Arnold M, Needleman PD. A Review of Policyholders' Reasonable Expectations British Actuarial Journal. 8: 905-915. DOI: 10.1017/S1357321700004001 |
0.023 |
|
| 1978 |
Turk J, Weiss SJ, Davis JE, Needleman P. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. Prostaglandins. 16: 291-309. PMID 704934 |
0.022 |
|
| 2004 |
Dullaway DW, Needleman PD. Realistic Liabilities and Risk Capital Margins for With-Profits Business. A Discussion Paper British Actuarial Journal. 10: 185-222. DOI: 10.1017/S1357321700002804 |
0.021 |
|
| 1977 |
Raz A, Minkes MS, Needleman P. Endoperoxides and thromboxanes. Structural determinants for platelet aggregation and vasoconstriction. Biochimica Et Biophysica Acta. 488: 305-11. PMID 560869 DOI: 10.1016/0005-2760(77)90188-6 |
0.017 |
|
| 1995 |
Isakson P, Seibert K, Masferrer J, Salvemini D, Lee L, Needleman P. Discovery of a better aspirin. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 49-54. PMID 7732896 |
0.017 |
|
| 2001 |
Needleman P. The IRI Medalist's Address: From a Twinkle In the Eye To a Blockbuster Drug Research-Technology Management. 44: 38-41. DOI: 10.1080/08956308.2001.11671463 |
0.01 |
|
| 2001 |
Needleman P. From a twinkle in the eye to a blockbuster drug Research Technology Management. 44: 38-39+41. |
0.01 |
|
| 1988 |
Unger E, Needleman P, Cullis P, Tilcock C. Gadolinium-DTPA liposomes as a potential MRI contrast agent. Work in progress. Investigative Radiology. 23: 928-32. PMID 3203995 |
0.01 |
|
| 1961 |
NEEDLEMAN P. Treatment and prophylaxis of radiation damage. American Journal of Pharmacy and the Sciences Supporting Public Health. 133: 166-82. PMID 13728109 |
0.01 |
|
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