Hamed Jafar-Nejad - Publications

Affiliations: 
Baylor College of Medicine, Houston, TX 
Area:
regulation of signaling pathways

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pandey A, Galeone A, Han SY, Story BA, Consonni G, Mueller WF, Steinmetz LM, Vaccari T, Jafar-Nejad H. Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila. Nature Communications. 14: 5667. PMID 37704604 DOI: 10.1038/s41467-023-40910-w  0.486
2023 Pandey A, Galeone A, Han SY, Story BA, Consonni G, Mueller WF, Steinmetz LM, Vaccari T, Jafar-Nejad H. Gut barrier defects, increased intestinal innate immune response, and enhanced lipid catabolism drive lethality in -glycanase 1 deficient . Biorxiv : the Preprint Server For Biology. PMID 37066398 DOI: 10.1101/2023.04.07.536022  0.469
2022 Pandey A, Adams JM, Han SY, Jafar-Nejad H. NGLY1 Deficiency, a Congenital Disorder of Deglycosylation: From Disease Gene Function to Pathophysiology. Cells. 11. PMID 35406718 DOI: 10.3390/cells11071155  0.538
2021 Pandey A, Jafar-Nejad H. Tracing the NGLY1 footprints: Insights from Drosophila. Journal of Biochemistry. PMID 34270726 DOI: 10.1093/jb/mvab084  0.552
2020 Han SY, Pandey A, Moore T, Galeone A, Duraine L, Cowan TM, Jafar-Nejad H. A conserved role for AMP-activated protein kinase in NGLY1 deficiency. Plos Genetics. 16: e1009258. PMID 33315951 DOI: 10.1371/journal.pgen.1009258  0.551
2020 Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H. Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation. Elife. 9. PMID 32720893 DOI: 10.7554/Elife.55596  0.604
2020 Pandey A, Niknejad N, Jafar-Nejad H. Multifaceted regulation of Notch signaling by glycosylation. Glycobiology. PMID 32472127 DOI: 10.1093/Glycob/Cwaa049  0.645
2020 Servián-Morilla E, Cabrera-Serrano M, Johnson K, Pandey A, Ito A, Rivas E, Chamova T, Muelas N, Mongini T, Nafissi S, Claeys KG, Grewal RP, Takeuchi M, Hao H, Bönnemann C, ... ... Jafar-Nejad H, et al. POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern. Acta Neuropathologica. PMID 31897643 DOI: 10.1007/S00401-019-02117-6  0.582
2020 Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H. Author response: Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation Elife. DOI: 10.7554/Elife.55596.Sa2  0.576
2019 Pandey A, Harvey BM, Lopez MF, Ito A, Haltiwanger RS, Jafar-Nejad H. Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila. Cell Reports. 29: 2054-2066.e6. PMID 31722217 DOI: 10.1016/J.Celrep.2019.10.027  0.606
2018 Pandey A, Li-Kroeger D, Sethi MK, Lee TV, Buettner FFR, Bakker H, Jafar-Nejad H. Sensitized genetic backgrounds reveal differential roles for EGF repeat xylosyltransferases in Drosophila Notch signaling. Glycobiology. PMID 30169771 DOI: 10.1093/Glycob/Cwy080  0.792
2018 Pandey A, Jafar-Nejad H. Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands. Journal of Visualized Experiments : Jove. PMID 29364239 DOI: 10.3791/56919  0.59
2017 Wu J, Hunt SD, Matthias N, Servián-Morilla E, Lo J, Jafar-Nejad H, Paradas C, Darabi R. Generation of an induced pluripotent stem cell line (CSCRMi001-A) from a patient with a new type of limb-girdle muscular dystrophy (LGMD) due to a missense mutation in POGLUT1 (Rumi). Stem Cell Research. 24: 102-105. PMID 29034878 DOI: 10.1016/J.Scr.2017.08.020  0.374
2017 Galeone A, Han SY, Huang C, Hosomi A, Suzuki T, Jafar-Nejad H. Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1. Elife. 6. PMID 28826503 DOI: 10.7554/Elife.27612  0.436
2017 Lee TV, Pandey A, Jafar-Nejad H. Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila. Plos Genetics. 13: e1006723. PMID 28394891 DOI: 10.1371/Journal.Pgen.1006723  0.721
2017 Galeone A, Han SY, Huang C, Hosomi A, Suzuki T, Jafar-Nejad H. Author response: Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1 Elife. DOI: 10.7554/Elife.27612.021  0.344
2016 Servián-Morilla E, Takeuchi H, Lee TV, Clarimon J, Mavillard F, Area-Gómez E, Rivas E, Nieto-González JL, Rivero MC, Cabrera-Serrano M, Gómez-Sánchez L, Martínez-López JA, Estrada B, Márquez C, Morgado Y, ... ... Jafar-Nejad H, et al. A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss. Embo Molecular Medicine. 8: 1289-1309. PMID 27807076 DOI: 10.15252/Emmm.201505815  0.628
2016 Harvey BM, Rana NA, Moss H, Leonardi J, Jafar-Nejad H, Haltiwanger RS. Mapping sites of O-glycosylation and fringe elongation on Drosophila Notch. The Journal of Biological Chemistry. PMID 27268051 DOI: 10.1074/Jbc.M116.732537  0.318
2015 Haltom AR, Jafar-Nejad H. The multiple roles of epidermal growth factor repeat O-glycans in animal development. Glycobiology. 25: 1027-42. PMID 26175457 DOI: 10.1093/Glycob/Cwv052  0.4
2015 He P, Grotzke JE, Ng BG, Gunel M, Jafar-Nejad H, Cresswell P, Enns GM, Freeze HH. A congenital disorder of deglycosylation: Biochemical characterization of N-glycanase 1 deficiency in patient fibroblasts. Glycobiology. 25: 836-44. PMID 25900930 DOI: 10.1093/Glycob/Cwv024  0.303
2015 Lee TV, Jafar-Nejad H. O-Glucose Glycans in Drosophila Notch Signaling Glycoscience: Biology and Medicine. 849-856. DOI: 10.1007/978-4-431-54841-6_164  0.585
2014 Haltom AR, Lee TV, Harvey BM, Leonardi J, Chen YJ, Hong Y, Haltiwanger RS, Jafar-Nejad H. The protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in Drosophila. Plos Genetics. 10: e1004795. PMID 25412384 DOI: 10.1371/Journal.Pgen.1004795  0.649
2014 LeBon L, Lee TV, Sprinzak D, Jafar-Nejad H, Elowitz MB. Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. Elife. 3: e02950. PMID 25255098 DOI: 10.7554/Elife.02950  0.609
2014 Leonardi J, Jafar-Nejad H. Structure-function analysis of Drosophila Notch using genomic rescue transgenes. Methods in Molecular Biology (Clifton, N.J.). 1187: 29-46. PMID 25053479 DOI: 10.1007/978-1-4939-1139-4_3  0.461
2014 LeBon L, Lee TV, Sprinzak D, Jafar-Nejad H, Elowitz MB. Correction: Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states Elife. 3. DOI: 10.7554/Elife.04998  0.611
2014 Haltom AR, Lee TV, Harvey BM, Leonardi J, Chen Y, Hong Y, Haltiwanger RS, Jafar-Nejad H. Loss of O -glucose on Notch cannot explain the rumi −/− rhabdomere attachment phenotype. Plos Genetics. DOI: 10.1371/Journal.Pgen.1004795.G002  0.571
2013 Lee TV, Sethi MK, Leonardi J, Rana NA, Buettner FF, Haltiwanger RS, Bakker H, Jafar-Nejad H. Negative regulation of notch signaling by xylose. Plos Genetics. 9: e1003547. PMID 23754965 DOI: 10.1371/Journal.Pgen.1003547  0.684
2011 Takeuchi H, Fernández-Valdivia RC, Caswell DS, Nita-Lazar A, Rana NA, Garner TP, Weldeghiorghis TK, Macnaughtan MA, Jafar-Nejad H, Haltiwanger RS. Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 108: 16600-5. PMID 21949356 DOI: 10.1073/Pnas.1109696108  0.379
2011 Leonardi J, Fernandez-Valdivia R, Li YD, Simcox AA, Jafar-Nejad H. Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling. Development (Cambridge, England). 138: 3569-78. PMID 21771811 DOI: 10.1242/Dev.068361  0.432
2011 Fernandez-Valdivia R, Takeuchi H, Samarghandi A, Lopez M, Leonardi J, Haltiwanger RS, Jafar-Nejad H. Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi. Development (Cambridge, England). 138: 1925-34. PMID 21490058 DOI: 10.1242/Dev.060020  0.491
2010 Lee TV, Takeuchi H, Jafar-Nejad H. Regulation of notch signaling via O-glucosylation insights from Drosophila studies. Methods in Enzymology. 480: 375-98. PMID 20816218 DOI: 10.1016/S0076-6879(10)80017-5  0.689
2010 Jafar-Nejad H, Leonardi J, Fernandez-Valdivia R. Role of glycans and glycosyltransferases in the regulation of Notch signaling. Glycobiology. 20: 931-49. PMID 20368670 DOI: 10.1093/Glycob/Cwq053  0.471
2008 Simcox AA, Austin CL, Jacobsen TL, Jafar-Nejad H. Drosophila embryonic 'fibroblasts': extending mutant analysis in vitro. Fly. 2: 306-9. PMID 19077546 DOI: 10.4161/Fly.7427  0.359
2008 Acar M, Jafar-Nejad H, Takeuchi H, Rajan A, Ibrani D, Rana NA, Pan H, Haltiwanger RS, Bellen HJ. Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. Cell. 132: 247-58. PMID 18243100 DOI: 10.1016/J.Cell.2007.12.016  0.753
2007 Rogaeva A, Ou XM, Jafar-Nejad H, Lemonde S, Albert PR. Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene. The Journal of Biological Chemistry. 282: 20897-905. PMID 17535813 DOI: 10.1074/Jbc.M610038200  0.353
2006 Acar M, Jafar-Nejad H, Giagtzoglou N, Yallampalli S, David G, He Y, Delidakis C, Bellen HJ. Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development (Cambridge, England). 133: 1979-89. PMID 16624856 DOI: 10.1242/Dev.02372  0.78
2006 Jafar-Nejad H, Tien AC, Acar M, Bellen HJ. Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin. Development (Cambridge, England). 133: 1683-92. PMID 16554363 DOI: 10.1242/Dev.02338  0.77
2006 Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nature Cell Biology. 8: 27-36. PMID 16341207 DOI: 10.1038/Ncb1339  0.776
2005 Jafar-Nejad H, Andrews HK, Acar M, Bayat V, Wirtz-Peitz F, Mehta SQ, Knoblich JA, Bellen HJ. Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Developmental Cell. 9: 351-63. PMID 16137928 DOI: 10.1016/J.Devcel.2005.06.010  0.749
2005 Tsuda H, Jafar-Nejad H, Patel AJ, Sun Y, Chen HK, Rose MF, Venken KJ, Botas J, Orr HT, Bellen HJ, Zoghbi HY. The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell. 122: 633-44. PMID 16122429 DOI: 10.1016/J.Cell.2005.06.012  0.743
2004 Jafar-Nejad H, Bellen HJ. Gfi/Pag-3/senseless zinc finger proteins: a unifying theme? Molecular and Cellular Biology. 24: 8803-12. PMID 15456856 DOI: 10.1128/Mcb.24.20.8803-8812.2004  0.6
2004 Quan XJ, Denayer T, Yan J, Jafar-Nejad H, Philippi A, Lichtarge O, Vleminckx K, Hassan BA. Evolution of neural precursor selection: functional divergence of proneural proteins. Development (Cambridge, England). 131: 1679-89. PMID 15084454 DOI: 10.1242/Dev.01055  0.625
2003 Jafar-Nejad H, Acar M, Nolo R, Lacin H, Pan H, Parkhurst SM, Bellen HJ. Senseless acts as a binary switch during sensory organ precursor selection. Genes & Development. 17: 2966-78. PMID 14665671 DOI: 10.1101/Gad.1122403  0.744
2003 Zhai RG, Hiesinger PR, Koh TW, Verstreken P, Schulze KL, Cao Y, Jafar-Nejad H, Norga KK, Pan H, Bayat V, Greenbaum MP, Bellen HJ. Mapping Drosophila mutations with molecularly defined P element insertions. Proceedings of the National Academy of Sciences of the United States of America. 100: 10860-5. PMID 12960394 DOI: 10.1073/Pnas.1832753100  0.677
2003 Ou XM, Lemonde S, Jafar-Nejad H, Bown CD, Goto A, Rogaeva A, Albert PR. Freud-1: A neuronal calcium-regulated repressor of the 5-HT1A receptor gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7415-25. PMID 12917378 DOI: 10.1523/Jneurosci.23-19-07415.2003  0.363
2002 Jafar-Nejad H, Norga K, Bellen H. Numb: "Adapting" notch for endocytosis. Developmental Cell. 3: 155-6. PMID 12194846 DOI: 10.1016/S1534-5807(02)00228-9  0.754
2000 Ou XM, Jafar-Nejad H, Storring JM, Meng JH, Lemonde S, Albert PR. Novel dual repressor elements for neuronal cell-specific transcription of the rat 5-HT1A receptor gene. The Journal of Biological Chemistry. 275: 8161-8. PMID 10713139 DOI: 10.1074/Jbc.275.11.8161  0.336
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