Michael A. Beaven - Publications

Affiliations: 
National Institutes of Health, Bethesda, MD 

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Olivera A, Beaven MA, Metcalfe DD. Mast Cells Signal their Importance in Health and Disease. The Journal of Allergy and Clinical Immunology. PMID 29454835 DOI: 10.1016/J.Jaci.2018.01.034  0.402
2017 Kim DK, Beaven MA, Metcalfe DD, Olivera A. Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells. The Journal of Allergy and Clinical Immunology. PMID 29031599 DOI: 10.1016/J.Jaci.2017.08.030  0.359
2016 Cruse G, Yin Y, Fukuyama T, Desai A, Arthur GK, Bäumer W, Beaven MA, Metcalfe DD. Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872312 DOI: 10.1073/Pnas.1608520113  0.38
2016 Kim DK, Beaven MA, Kulinski JM, Desai A, Bandara G, Bai Y, Prussin C, Schwartz LB, Komarow H, Metcalfe DD, Olivera A. Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis. Plos One. 11: e0162831. PMID 27611333 DOI: 10.1371/Journal.Pone.0162831  0.346
2016 Kim AR, Kim HS, Kim do K, Nam ST, Kim HW, Park YH, Lee D, Lee MB, Lee JH, Kim B, Beaven MA, Kim HS, Kim YM, Choi WS. Mesenteric IL-10-producing CD5(+) regulatory B cells suppress cow's milk casein-induced allergic responses in mice. Scientific Reports. 6: 19685. PMID 26785945 DOI: 10.1038/Srep19685  0.315
2016 Desai A, Jung MY, Olivera A, Gilfillan AM, Prussin C, Kirshenbaum AS, Beaven MA, Metcalfe DD. IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3. The Journal of Allergy and Clinical Immunology. PMID 26774658 DOI: 10.1016/J.Jaci.2015.09.059  0.316
2016 Kim D, Beaven MA, Kulinski J, Desai A, Cruse G, Prussin C, Komarow HD, Carter MC, Metcalfe DD, Olivera A. Constitutive KIT Activity and IL-6 Production in Mast Cells Alters Levels of Reactive Oxygen Species (ROS) and the Scavenger Protein DJ-1 in Mastocytosis The Journal of Allergy and Clinical Immunology. 137. DOI: 10.1016/J.Jaci.2015.12.1168  0.302
2015 Bandara G, Beaven MA, Olivera A, Gilfillan AM, Metcalfe DD. Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33. European Journal of Immunology. PMID 26256265 DOI: 10.1002/Eji.201545501  0.331
2015 Kim HS, Kim AR, Kim do K, Kim HW, Park YH, Jang GH, Kim B, Park YM, You JS, Kim HS, Beaven MA, Kim YM, Choi WS. Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses. Science Signaling. 8: ra28. PMID 25783157 DOI: 10.1126/Scisignal.2005861  0.365
2015 Cruse G, Beaven MA, Music SC, Bradding P, Gilfillan AM, Metcalfe DD. The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling. Molecular Biology of the Cell. 26: 1711-27. PMID 25717186 DOI: 10.1091/Mbc.E14-07-1221  0.362
2015 Cruse G, Beaven MA, Music SC, Bradding P, Metcalfe DD. The Fcεriβ Homologue, MS4A4, Promotes Fcεri-Dependent Human Mast Cell Degranulation By Facilitating PLCγ1 Signaling The Journal of Allergy and Clinical Immunology. 135. DOI: 10.1016/J.Jaci.2014.12.1718  0.336
2015 Bandara G, Beaven MA, Olivera A, Gilfillan AM, Metcalfe DD. Activated Mast Cells Produce Soluble ST2, a Decoy Receptor for IL-33 The Journal of Allergy and Clinical Immunology. 135. DOI: 10.1016/J.Jaci.2014.12.1143  0.325
2014 Smrz D, Cruse G, Beaven MA, Kirshenbaum A, Metcalfe DD, Gilfillan AM. Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation. Journal of Immunology (Baltimore, Md. : 1950). 193: 5924-32. PMID 25378594 DOI: 10.4049/Jimmunol.1303495  0.398
2013 Kim do K, Kim HS, Kim AR, Jang GH, Kim HW, Park YH, Kim B, Park YM, Beaven MA, Kim YM, Choi WS. The scaffold protein prohibitin is required for antigen-stimulated signaling in mast cells. Science Signaling. 6: ra80. PMID 24023254 DOI: 10.1126/Scisignal.2004098  0.417
2013 Smrž D, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM. Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells. European Journal of Immunology. 43: 1873-82. PMID 23616175 DOI: 10.1002/Eji.201243214  0.392
2013 Medic N, Desai A, Olivera A, Abramowitz J, Birnbaumer L, Beaven MA, Gilfillan AM, Metcalfe DD. Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production. Cell Calcium. 53: 315-26. PMID 23489970 DOI: 10.1016/J.Ceca.2013.02.001  0.338
2013 Smrž D, Bandara G, Zhang S, Mock BA, Beaven MA, Metcalfe DD, Gilfillan AM. A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses. Journal of Immunological Methods. 390: 52-62. PMID 23357051 DOI: 10.1016/J.Jim.2013.01.008  0.374
2013 Jung MY, Smrž D, Desai A, Bandara G, Ito T, Iwaki S, Kang JH, Andrade MV, Hilderbrand SC, Brown JM, Beaven MA, Metcalfe DD, Gilfillan AM. IL-33 induces a hyporesponsive phenotype in human and mouse mast cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 531-8. PMID 23248261 DOI: 10.4049/Jimmunol.1201576  0.305
2013 Kim do K, Kim HS, Kim AR, Kim JH, Kim B, Noh G, Kim HS, Beaven MA, Kim YM, Choi WS. DJ-1 regulates mast cell activation and IgE-mediated allergic responses. The Journal of Allergy and Clinical Immunology. 131: 1653-62. PMID 23182168 DOI: 10.1016/J.Jaci.2012.10.012  0.412
2012 Ito T, Smrž D, Jung MY, Bandara G, Desai A, Smržová Å , Kuehn HS, Beaven MA, Metcalfe DD, Gilfillan AM. Stem cell factor programs the mast cell activation phenotype. Journal of Immunology (Baltimore, Md. : 1950). 188: 5428-37. PMID 22529299 DOI: 10.4049/Jimmunol.1103366  0.415
2012 Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V, Chung JH. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell. 148: 421-33. PMID 22304913 DOI: 10.1016/J.Cell.2012.01.017  0.324
2011 Gilfillan AM, Beaven MA. Regulation of mast cell responses in health and disease. Critical Reviews in Immunology. 31: 475-529. PMID 22321108 DOI: 10.1615/Critrevimmunol.V31.I6.30  0.371
2011 Medic N, Desai A, Komarow H, Burch LH, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM. Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria. Cell Calcium. 50: 473-80. PMID 21906810 DOI: 10.1016/J.Ceca.2011.08.003  0.414
2011 Kuehn HS, Jung MY, Beaven MA, Metcalfe DD, Gilfillan AM. Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release. Immunology Letters. 141: 45-54. PMID 21798286 DOI: 10.1016/J.Imlet.2011.07.002  0.422
2011 Lee JH, Kim JW, Kim do K, Kim HS, Park HJ, Park DK, Kim AR, Kim B, Beaven MA, Park KL, Kim YM, Choi WS. The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice. Journal of Immunology (Baltimore, Md. : 1950). 187: 1807-15. PMID 21746961 DOI: 10.4049/Jimmunol.1100296  0.409
2011 Ma HT, Beaven MA. Regulators of Ca(2+) signaling in mast cells: potential targets for treatment of mast cell-related diseases? Advances in Experimental Medicine and Biology. 716: 62-90. PMID 21713652 DOI: 10.1007/978-1-4419-9533-9_5  0.344
2011 Andrade MV, Iwaki S, Ropert C, Gazzinelli RT, Cunha-Melo JR, Beaven MA. Amplification of cytokine production through synergistic activation of NFAT and AP-1 following stimulation of mast cells with antigen and IL-33. European Journal of Immunology. 41: 760-72. PMID 21308681 DOI: 10.1002/Eji.201040718  0.323
2011 Kuehn HS, Jung MY, Beaven MA, Metcalfe DD, Gilfillan AM. Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. The Journal of Biological Chemistry. 286: 391-402. PMID 20980255 DOI: 10.1074/Jbc.M110.164772  0.412
2010 Kuehn HS, RÃ¥dinger M, Brown JM, Ali K, Vanhaesebroeck B, Beaven MA, Metcalfe DD, Gilfillan AM. Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells. Journal of Cell Science. 123: 2576-85. PMID 20587594 DOI: 10.1242/Jcs.071043  0.429
2010 Mun SH, Ko NY, Kim HS, Kim JW, Kim do K, Kim AR, Lee SH, Kim YG, Lee CK, Lee SH, Kim BK, Beaven MA, Kim YM, Choi WS. Interleukin-33 stimulates formation of functional osteoclasts from human CD14(+) monocytes. Cellular and Molecular Life Sciences : Cmls. 67: 3883-92. PMID 20532808 DOI: 10.1007/S00018-010-0410-Y  0.311
2009 Lisboa FA, Peng Z, Combs CA, Beaven MA. Phospholipase d promotes lipid microdomain-associated signaling events in mast cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 5104-12. PMID 19794068 DOI: 10.4049/Jimmunol.0802728  0.383
2009 Ma HT, Beaven MA. Regulation of Ca2+ signaling with particular focus on mast cells. Critical Reviews in Immunology. 29: 155-86. PMID 19496745 DOI: 10.1615/Critrevimmunol.V29.I2.40  0.313
2009 Park SK, Qiao H, Beaven MA. Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator. Molecular Immunology. 46: 2133-9. PMID 19371953 DOI: 10.1016/J.Molimm.2009.03.013  0.408
2009 Beaven MA. Our perception of the mast cell from Paul Ehrlich to now. European Journal of Immunology. 39: 11-25. PMID 19130582 DOI: 10.1002/Eji.200838899  0.364
2009 Park SK, Beaven MA. Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells. Molecular Immunology. 46: 492-7. PMID 19036452 DOI: 10.1016/J.Molimm.2008.10.011  0.366
2008 Kuehn HS, Swindle EJ, Kim MS, Beaven MA, Metcalfe DD, Gilfillan AM. The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 7706-12. PMID 19017959 DOI: 10.4049/Jimmunol.181.11.7706  0.398
2008 Lee JH, Kim JW, Ko NY, Mun SH, Her E, Kim BK, Han JW, Lee HY, Beaven MA, Kim YM, Choi WS. Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk. The Journal of Allergy and Clinical Immunology. 121: 1225-31. PMID 18394691 DOI: 10.1016/J.Jaci.2007.12.1160  0.444
2008 Ma HT, Peng Z, Hiragun T, Iwaki S, Gilfillan AM, Beaven MA. Canonical transient receptor potential 5 channel in conjunction with Orai1 and STIM1 allows Sr2+ entry, optimal influx of Ca2+, and degranulation in a rat mast cell line. Journal of Immunology (Baltimore, Md. : 1950). 180: 2233-9. PMID 18250430 DOI: 10.4049/Jimmunol.180.4.2233  0.313
2008 Kuehn HS, Beaven MA, Ma HT, Kim MS, Metcalfe DD, Gilfillan AM. Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release. Cellular Signalling. 20: 625-36. PMID 18207701 DOI: 10.1016/J.Cellsig.2007.11.016  0.434
2008 Jensen BM, Beaven MA, Iwaki S, Metcalfe DD, Gilfillan AM. Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation. The Journal of Pharmacology and Experimental Therapeutics. 324: 128-38. PMID 17925481 DOI: 10.1124/Jpet.107.125237  0.433
2007 Beaven MA. Division of labor: specialization of sphingosine kinases in mast cells. Immunity. 26: 271-3. PMID 17376388 DOI: 10.1016/J.Immuni.2007.03.002  0.359
2006 Mitra P, Oskeritzian CA, Payne SG, Beaven MA, Milstien S, Spiegel S. Role of ABCC1 in export of sphingosine-1-phosphate from mast cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 16394-9. PMID 17050692 DOI: 10.1073/Pnas.0603734103  0.38
2006 Hiragun T, Peng Z, Beaven MA. Cutting edge: dexamethasone negatively regulates Syk in mast cells by up-regulating SRC-like adaptor protein. Journal of Immunology (Baltimore, Md. : 1950). 177: 2047-50. PMID 16887961 DOI: 10.4049/Jimmunol.177.4.2047  0.428
2006 Lee JH, Kim YM, Kim NW, Kim JW, Her E, Kim BK, Kim JH, Ryu SH, Park JW, Seo DW, Han JW, Beaven MA, Choi WS. Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells. Blood. 108: 956-64. PMID 16861349 DOI: 10.1182/Blood-2005-10-009159  0.416
2006 Furumoto Y, Brooks S, Olivera A, Takagi Y, Miyagishi M, Taira K, Casellas R, Beaven MA, Gilfillan AM, Rivera J. Cutting Edge: Lentiviral short hairpin RNA silencing of PTEN in human mast cells reveals constitutive signals that promote cytokine secretion and cell survival. Journal of Immunology (Baltimore, Md. : 1950). 176: 5167-71. PMID 16621980 DOI: 10.4049/Jimmunol.176.9.5167  0.395
2006 Qiao H, Andrade MV, Lisboa FA, Morgan K, Beaven MA. FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells. Blood. 107: 610-8. PMID 16174756 DOI: 10.1182/Blood-2005-06-2271  0.359
2005 Iwaki S, Tkaczyk C, Satterthwaite AB, Halcomb K, Beaven MA, Metcalfe DD, Gilfillan AM. Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit. The Journal of Biological Chemistry. 280: 40261-70. PMID 16176929 DOI: 10.1074/Jbc.M506063200  0.415
2005 Peng Z, Beaven MA. An essential role for phospholipase D in the activation of protein kinase C and degranulation in mast cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 5201-8. PMID 15843515 DOI: 10.4049/Jimmunol.174.9.5201  0.396
2005 Hiragun T, Peng Z, Beaven MA. Dexamethasone up-regulates the inhibitory adaptor protein Dok-1 and suppresses downstream activation of the mitogen-activated protein kinase pathway in antigen-stimulated RBL-2H3 mast cells. Molecular Pharmacology. 67: 598-603. PMID 15608142 DOI: 10.1124/Mol.104.008607  0.413
2004 Choi WS, Hiragun T, Lee JH, Kim YM, Kim HP, Chahdi A, Her E, Han JW, Beaven MA. Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr. Molecular and Cellular Biology. 24: 6980-92. PMID 15282299 DOI: 10.1128/Mcb.24.16.6980-6992.2004  0.357
2004 Hundley TR, Gilfillan AM, Tkaczyk C, Andrade MV, Metcalfe DD, Beaven MA. Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells. Blood. 104: 2410-7. PMID 15217825 DOI: 10.1182/Blood-2004-02-0631  0.394
2004 Andrade MV, Hiragun T, Beaven MA. Dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mast cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 7254-62. PMID 15187100 DOI: 10.4049/Jimmunol.172.12.7254  0.434
2004 Tkaczyk C, Beaven MA, Brachman S, Metcalfe DD, Gilfillan AM. FcϵRI-mediated-activation of PLC-γ is not defective in mouse bone marrow-derived mast cells (BMMC) lacking PI-3 kinase-p85α or p85β gene products☆ The Journal of Allergy and Clinical Immunology. 113. DOI: 10.1016/J.Jaci.2004.01.093  0.351
2003 Kirshenbaum AS, Akin C, Wu Y, Rottem M, Goff JP, Beaven MA, Rao VK, Metcalfe DD. Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. Leukemia Research. 27: 677-82. PMID 12801524 DOI: 10.1016/S0145-2126(02)00343-0  0.35
2003 Chahdi A, Choi WS, Kim YM, Beaven MA. Mastoparan selectively activates phospholipase D2 in cell membranes. The Journal of Biological Chemistry. 278: 12039-45. PMID 12556526 DOI: 10.1074/Jbc.M212084200  0.368
2003 Kirshenbaum AS, Akin C, Wu Y, Rottem M, Goff JP, Beaven MA, Rao VK, Metcalfe DD. Corrigendum to “Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation aggregation of FcεRI or FcγRI” [Leuk. Res. 27 (2003) 677–682] Leukemia Research. 27: 1171. DOI: 10.1016/S0145-2126(03)00157-7  0.347
2002 Chahdi A, Choi WS, Kim YM, Fraundorfer PF, Beaven MA. Serine/threonine protein kinases synergistically regulate phospholipase D1 and 2 and secretion in RBL-2H3 mast cells. Molecular Immunology. 38: 1269-76. PMID 12217394 DOI: 10.1016/S0161-5890(02)00074-3  0.39
2002 Choi WS, Chahdi A, Kim YM, Fraundorfer PF, Beaven MA. Regulation of phospholipase D and secretion in mast cells by protein kinase A and other protein kinases. Annals of the New York Academy of Sciences. 968: 198-212. PMID 12119277 DOI: 10.1111/J.1749-6632.2002.Tb04336.X  0.399
2002 Choi WS, Kim YM, Combs C, Frohman MA, Beaven MA. Phospholipases D1 and D2 regulate different phases of exocytosis in mast cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5682-9. PMID 12023367 DOI: 10.4049/Jimmunol.168.11.5682  0.318
2001 Hundley TR, Prasad AR, Beaven MA. Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase. Journal of Immunology (Baltimore, Md. : 1950). 167: 1629-36. PMID 11466386 DOI: 10.4049/Jimmunol.167.3.1629  0.387
2001 Chaves-Dias C, Hundley TR, Gilfillan AM, Kirshenbaum AS, Cunha-Melo JR, Metcalfe DD, Beaven MA. Induction of telomerase activity during development of human mast cells from peripheral blood CD34+ cells: comparisons with tumor mast-cell lines. Journal of Immunology (Baltimore, Md. : 1950). 166: 6647-56. PMID 11359819 DOI: 10.4049/Jimmunol.166.11.6647  0.383
2000 Cissel DS, Beaven MA. Disruption of Raf-1/heat shock protein 90 complex and Raf signaling by dexamethasone in mast cells. The Journal of Biological Chemistry. 275: 7066-70. PMID 10702272 DOI: 10.1074/Jbc.275.10.7066  0.396
1999 Holbrook PG, Geetha V, Beaven MA, Munson PJ. Recognizing the pleckstrin homology domain fold in mammalian phospholipase D using hidden Markov models. Febs Letters. 448: 269-72. PMID 10218490 DOI: 10.1016/S0014-5793(99)00366-X  0.325
1998 Kassessinoff TA, Gabet A, Beaven MA, Sagi-Eisenberg R. Inositol polyphosphates regulate the membrane interactions of the endosomal p100, G-protein-related protein. Biochimica Et Biophysica Acta. 1394: 111-20. PMID 9767143 DOI: 10.1016/S0005-2760(98)00099-X  0.311
1998 Cissel DS, Fraundorfer PF, Beaven MA. Thapsigargin-induced secretion is dependent on activation of a cholera toxin-sensitive and phosphatidylinositol-3-kinase-regulated phospholipase D in a mast cell line. The Journal of Pharmacology and Experimental Therapeutics. 285: 110-8. PMID 9536000  0.318
1997 Zhang C, Baumgartner RA, Yamada K, Beaven MA. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. The Journal of Biological Chemistry. 272: 13397-402. PMID 9148963 DOI: 10.1074/Jbc.272.20.13397  0.318
1996 Beaven MA, Baumgartner RA. Downstream signals initiated in mast cells by Fc epsilon RI and other receptors. Current Opinion in Immunology. 8: 766-72. PMID 8994853 DOI: 10.1016/S0952-7915(96)80002-1  0.434
1996 Beaven MA. Calcium signalling: sphingosine kinase versus phospholipase C? Current Biology : Cb. 6: 798-801. PMID 8805291 DOI: 10.1016/S0960-9822(02)00598-5  0.339
1996 Choi OH, Park CS, Itoh K, Adelstein RS, Beaven MA. Cloning of the cDNA encoding rat myosin heavy chain-A and evidence for the absence of myosin heavy chain-B in cultured rat mast (RBL-2H3) cells. Journal of Muscle Research and Cell Motility. 17: 69-77. PMID 8740433 DOI: 10.1007/Bf00140325  0.335
1996 Jabril-Cuenod B, Zhang C, Scharenberg AM, Paolini R, Numerof R, Beaven MA, Kinet JP. Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2. The Journal of Biological Chemistry. 271: 16268-72. PMID 8663278 DOI: 10.1074/Jbc.271.27.16268  0.368
1996 Beaven MA, Ozawa K. Role of calcium, protein kinase C and MAP kinase in the activation of mast cells Allergology International. 45: 73-84. DOI: 10.2332/Allergolint.45.73  0.403
1995 Hirasawa N, Scharenberg A, Yamamura H, Beaven MA, Kinet JP. A requirement for Syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor. The Journal of Biological Chemistry. 270: 10960-7. PMID 7537741 DOI: 10.1074/Jbc.270.18.10960  0.337
1994 Baumgartner RA, Yamada K, Deramo VA, Beaven MA. Secretion of TNF from a rat mast cell line is a brefeldin A-sensitive and a calcium/protein kinase C-regulated process. Journal of Immunology (Baltimore, Md. : 1950). 153: 2609-17. PMID 8077671  0.31
1994 Baumgartner RA, Ozawa K, Cunha-Melo JR, Yamada K, Gusovsky F, Beaven MA. Studies with transfected and permeabilized RBL-2H3 cells reveal unique inhibitory properties of protein kinase C gamma. Molecular Biology of the Cell. 5: 475-84. PMID 8054687 DOI: 10.1091/Mbc.5.4.475  0.391
1991 Jones SV, Choi OH, Beaven MA. Carbachol induces secretion in a mast cell line (RBL-2H3) transfected with the ml muscarinic receptor gene. Febs Letters. 289: 47-50. PMID 1832647 DOI: 10.1016/0014-5793(91)80905-I  0.381
1989 Ali H, Cunha-Melo JR, Beaven MA. Receptor-mediated release of inositol 1,4,5-trisphosphate and inositol 1,4-bisphosphate in rat basophilic leukemia RBL-2H3 cells permeabilized with streptolysin O. Biochimica Et Biophysica Acta. 1010: 88-99. PMID 2642390 DOI: 10.1016/0167-4889(89)90188-2  0.377
1988 Beaven MA, Cunha-Melo JR. Membrane phosphoinositide-activated signals in mast cells and basophils. Progress in Allergy. 42: 123-84. PMID 2845425 DOI: 10.1159/000415507  0.333
1988 Lo TN, Eng SP, Jaseph LA, Beaven MA, Lo CS. Cardiotoxin from cobra venom increases the level of phosphatidylinositol 4-monophosphate and phosphatidylinositol kinase activity in two cell lines. Biochimica Et Biophysica Acta. 970: 51-60. PMID 2453219 DOI: 10.1016/0167-4889(88)90221-2  0.418
1987 Paul WE, Mizuguchi J, Beaven MA, Hornbeck P, Tsang W, Ohara J. B lymphocyte activation. The roles of receptor cross-linkage and BSF-1. Advances in Experimental Medicine and Biology. 213: 207-14. PMID 3498299 DOI: 10.1007/978-1-4684-5323-2_20  0.323
1987 Beaven MA, Maeyama K, Wolde-Mussie E, Lo TN, Ali H, Cunha-Melo JR. Mechanism of signal transduction in mast cells and basophils: studies with RBL-2H3 cells. Agents and Actions. 20: 137-45. PMID 3300209 DOI: 10.1007/Bf02074652  0.358
1986 Mizuguchi J, Beaven MA, Li JH, Paul WE. Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 4474-8. PMID 3086884 DOI: 10.1073/Pnas.83.12.4474  0.363
1986 WoldeMussie E, Aiken D, Beaven MA. Evidence for rapid histamine turnover and loss of histamine from immature rat mast cells. Biochemical Pharmacology. 35: 903-9. PMID 2420333 DOI: 10.1016/0006-2952(86)90075-4  0.417
1985 Robinson-White A, Baylin SB, Olivecrona T, Beaven MA. Binding of diamine oxidase activity to rat and guinea pig microvascular endothelial cells. Comparisons with lipoprotein lipase binding. The Journal of Clinical Investigation. 76: 93-100. PMID 3926823 DOI: 10.1172/Jci111983  0.316
1985 Lo TN, WoldeMussie E, Wilson N, Wu D, Beaven MA. Inflammatory response induced by intrapleural injection of antiserum to IgE in rat. An evaluation of the role of histamine. Biochemical Pharmacology. 34: 3901-7. PMID 2415131 DOI: 10.1016/0006-2952(85)90442-3  0.366
1984 Lo TN, Almeida AP, Beaven MA. Effect of indomethacin on generation of chemotactic activity in inflammatory exudates induced by carrageenan. European Journal of Pharmacology. 99: 31-43. PMID 6373311 DOI: 10.1016/0014-2999(84)90429-1  0.331
1982 Beaven MA, Roderick NB, Shaff RE, Soll AH. Histamine synthesis in intact and disrupted rat mast cells. Biochemical Pharmacology. 31: 1189-95. PMID 7092914 DOI: 10.1016/0006-2952(82)90003-X  0.411
1980 Horakova Z, Bayer BM, Almeida AP, Beaven MA. Evidence that histamine does not participate in carrageenan-induced pleurisy in rat. European Journal of Pharmacology. 62: 17-25. PMID 7371721 DOI: 10.1016/0014-2999(80)90476-8  0.358
1980 Almeida AP, Beaven MA. Gel formation with leucocytes and heparin. Life Sciences. 26: 549-55. PMID 6767888 DOI: 10.1016/0024-3205(80)90318-5  0.362
1980 de Mello MC, Bayer BM, Beaven MA. Evidence that prostaglandins do not have a role in the cytostatic action of anti-inflammatory drugs. Biochemical Pharmacology. 29: 311-8. PMID 6767484 DOI: 10.1016/0006-2952(80)90506-7  0.332
1979 Beaven MA, Shaff RE. New inhibitors of histamine-N-methyltransferase. Biochemical Pharmacology. 28: 183-8. PMID 34400 DOI: 10.1016/0006-2952(79)90500-8  0.307
1976 Shaff RE, Beaven MA. Turnover and synthesis of diamine oxidase (DAO) in rat tissues. Studies with heparin and cycloheximide. Biochemical Pharmacology. 25: 1057-62. PMID 817728 DOI: 10.1016/0006-2952(76)90496-2  0.326
1976 Moss J, De Mello MC, Vaughan M, Beaven MA. Effect of salicylates on histamine and L-histidine metabolism. Inhibition of imidazoleacetate phosphoribosyl transferase. The Journal of Clinical Investigation. 58: 137-41. PMID 180057 DOI: 10.1172/Jci108442  0.308
1975 Atkins FL, Beaven MA. Ornithine decarboxylase and histaminase (diamine oxidase) activities in rat thymus and their relationship to the thymus lymphocyte. Biochemical Pharmacology. 24: 763-8. PMID 804906 DOI: 10.1016/0006-2952(75)90117-3  0.397
1975 Beaven MA, Shaff RE. Study of the relationship of histaminase and diamine oxidase activities in various rat tissues and plasma by sensitive isotopic assay procedures. Biochemical Pharmacology. 24: 979-84. PMID 239723 DOI: 10.1016/0006-2952(75)90431-1  0.327
1974 Baxter JH, Beaven MA, Horáková Z. Effects of adrenergic agents, theophylline and other drugs on dextran edema and histamine release in rats. Biochemical Pharmacology. 23: 1211-7. PMID 4132694 DOI: 10.1016/0006-2952(74)90296-2  0.332
1973 Beaven MA, de Jong W. Presence of histaminase and ornithine decarboxylase activities in rat thymus. Biochemical Pharmacology. 22: 257-65. PMID 4202810 DOI: 10.1016/0006-2952(73)90278-5  0.319
1971 Isaac L, Cho AK, Beaven MA. Decline of histidine decarboxylase activity and histamine levels in rat stomach after reserpine. Biochemical Pharmacology. 20: 1453-61. PMID 5163084 DOI: 10.1016/0006-2952(71)90273-5  0.567
1970 Beaven MA, Horáková Z, Severs WB. Bacterial histidine decarboxylase in rat stomach. European Journal of Pharmacology. 11: 233-40. PMID 5447805 DOI: 10.1016/0014-2999(70)90052-X  0.3
1968 Reid WD, Volicer L, Smookler H, Beaven MA, Brodie BB. Brain amines and temperature regulation. Pharmacology. 1: 329-44. PMID 5710608 DOI: 10.1159/000135983  0.345
1968 Beaven MA, Horakova Z, Severs WB, Brodie BB. Selective labeling of histamine in rat gastric mucosa: application to measurement of turnover rate. The Journal of Pharmacology and Experimental Therapeutics. 161: 320-8. PMID 4297030  0.386
1967 Beaven MA, Horakova Z, Johnson HL, Erjavec F, Brodie BB. Selective labeling of histamine in rat gastric mucosa. Federation Proceedings. 26: 233-6. PMID 6018927  0.384
1967 Erjavec F, Beaven MA, Brodie BB. Uptake and release of 3-H-histamine in cat submaxillary gland. Federation Proceedings. 26: 237-40. PMID 4163658  0.407
1966 Johnson HL, Beaven MA, Erjavec F, Brodie BB. Selective labeling and release of nonmast-cell histamine. Life Sciences. 5: 115-23. PMID 5942046 DOI: 10.1016/0024-3205(66)90122-6  0.502
1963 MAICKEL RP, BEAVEN MA, BRODIE BB. IMPLICATIONS OF UPTAKE AND STORAGE OF NOREPINEPHRINE BY SYMPATHETIC NERVE ENDINGS. Life Sciences. 12: 953-8. PMID 14100226 DOI: 10.1016/0024-3205(63)90064-X  0.479
1963 BEAVEN MA, COSTA E, BRODIE BB. The turnover of norepinephrine in thyrotoxic and nonthyrotoxic mice. Life Sciences. 4: 241-6. PMID 13970010 DOI: 10.1016/0024-3205(63)90004-3  0.466
1963 Montanari R, Costa E, Beaven MA, Brodie BB. Turnover rates of norepinephrine in hearts of intact mice, rats and guinea pigs using tritiated norepinephrine Life Sciences. 2: 232-240. DOI: 10.1016/0024-3205(63)90003-1  0.458
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