Cassia R. Overk, Ph.D. - Publications

Affiliations: 
2007 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Pharmacology

16/62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chen S, Friesen J, McAlpine J, Overk C, Bolton J, Pauli G. Rebiogram enhances the search of bioactive natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556308  0.484
2009 Qin Z, Kastrati I, Ashgodom RT, Lantvit DD, Overk CR, Choi Y, van Breemen RB, Bolton JL, Thatcher GR. Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 161-9. PMID 18936111 DOI: 10.1124/Dmd.108.023408  0.599
2008 Overk CR, Guo J, Chadwick LR, Lantvit DD, Minassi A, Appendino G, Chen SN, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. Chemico-Biological Interactions. 176: 30-9. PMID 18619951 DOI: 10.1016/J.Cbi.2008.06.005  0.586
2008 Chang M, Overk CR, Kastrati I, Peng KW, Yao P, Qin ZH, Petukhov P, Bolton JL, Thatcher GR. Estrogenic activity of the equine estrogen metabolite, 4-methoxyequilenin. Advances in Experimental Medicine and Biology. 617: 601-7. PMID 18497087 DOI: 10.1007/978-0-387-69080-3_62  0.751
2008 Overk CR, Yao P, Chen S, Deng S, Imai A, Main M, Schinkovitz A, Farnsworth NR, Pauli GF, Bolton JL. High-content screening and mechanism-based evaluation of estrogenic botanical extracts. Combinatorial Chemistry & High Throughput Screening. 11: 283-93. PMID 18473738 DOI: 10.2174/138620708784246022  0.7
2008 Imai A, Yao P, Overk C, Bolton J, Nikolic D, van Breemen R, Pauli G. Phytochemical Investigation of the Estrogenic Aerial Parts of Cimicifuga racemosa (L.) Nutt(Ranunculaceae) Planta Medica. 74. DOI: 10.1055/S-2008-1075241  0.56
2007 Yu B, Dietz BM, Dunlap T, Kastrati I, Lantvit DD, Overk CR, Yao P, Qin Z, Bolton JL, Thatcher GR. Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms. Molecular Cancer Therapeutics. 6: 2418-28. PMID 17876041 DOI: 10.1158/1535-7163.Mct-07-0268  0.714
2007 Overk CR, Peng KW, Asghodom RT, Kastrati I, Lantvit DD, Qin Z, Frasor J, Bolton JL, Thatcher GR. Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene. Chemmedchem. 2: 1520-6. PMID 17654759 DOI: 10.1002/Cmdc.200700104  0.724
2007 Chang M, Peng KW, Kastrati I, Overk CR, Qin ZH, Yao P, Bolton JL, Thatcher GR. Activation of estrogen receptor-mediated gene transcription by the equine estrogen metabolite, 4-methoxyequilenin, in human breast cancer cells. Endocrinology. 148: 4793-802. PMID 17584965 DOI: 10.1210/En.2006-1568  0.754
2006 Booth NL, Overk CR, Yao P, Burdette JE, Nikolic D, Chen SN, Bolton JL, van Breemen RB, Pauli GF, Farnsworth NR. The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract. Journal of Alternative and Complementary Medicine (New York, N.Y.). 12: 133-9. PMID 16566672 DOI: 10.1089/Acm.2006.12.133  0.703
2006 Booth NL, Overk CR, Yao P, Totura S, Deng Y, Hedayat AS, Bolton JL, Pauli GF, Farnsworth NR. Seasonal variation of red clover (Trifolium pratense L., Fabaceae) isoflavones and estrogenic activity. Journal of Agricultural and Food Chemistry. 54: 1277-82. PMID 16478248 DOI: 10.1021/Jf052927U  0.638
2005 Overk CR, Yao P, Chadwick LR, Nikolic D, Sun Y, Cuendet MA, Deng Y, Hedayat AS, Pauli GF, Farnsworth NR, van Breemen RB, Bolton JL. Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). Journal of Agricultural and Food Chemistry. 53: 6246-53. PMID 16076101 DOI: 10.1021/Jf050448P  0.691
2005 Souza JSN, Machado LL, Pessoa ODL, Braz-Filho R, Overk CR, Yao P, Cordell GA, Lemos TLG. Pyrrolizidine alkaloids from Heliotropium indicum Journal of the Brazilian Chemical Society. 16: 1410-1414. DOI: 10.1590/S0103-50532005000800019  0.338
2004 Chadwick LR, Nikolic D, Burdette JE, Overk CR, Bolton JL, van Breemen RB, Fröhlich R, Fong HH, Farnsworth NR, Pauli GF. Estrogens and congeners from spent hops (Humulus lupulus). Journal of Natural Products. 67: 2024-32. PMID 15620245 DOI: 10.1021/Np049783I  0.681
2003 Graziani EI, Overk CR, Carter GT. Purification, structure determination, and antimicrobial activity of neutramycins B-G. Journal of Natural Products. 66: 1149-53. PMID 14510587 DOI: 10.1021/Np0301691  0.34
2003 Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin. Chemical Research in Toxicology. 16: 741-9. PMID 12807357 DOI: 10.1021/Tx030001F  0.743
Low-probability matches (unlikely to be authored by this person)
2013 Overk CR, Perez SE, Ma C, Taves MD, Soma KK, Mufson EJ. Sex steroid levels and AD-like pathology in 3xTgAD mice. Journal of Neuroendocrinology. 25: 131-44. PMID 22889357 DOI: 10.1111/j.1365-2826.2012.02374.x  0.181
2012 Overk CR, Lu PY, Wang YT, Choi J, Shaw JW, Thatcher GR, Mufson EJ. Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice. Neurobiology of Disease. 45: 479-87. PMID 21945538 DOI: 10.1016/j.nbd.2011.08.035  0.155
2010 Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ. Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease. Journal of Chemical Neuroanatomy. 40: 63-70. PMID 20347961 DOI: 10.1016/J.Jchemneu.2010.03.005  0.139
2014 Overk CR, Masliah E. Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 13680-1. PMID 25205809 DOI: 10.1073/Pnas.1414554111  0.137
2011 Overk CR, Borgia JA, Mufson EJ. A novel approach for long-term oral drug administration in animal research. Journal of Neuroscience Methods. 195: 194-9. PMID 21163304 DOI: 10.1016/j.jneumeth.2010.12.009  0.122
2022 Spencer B, Rissman RA, Overk C, Masliah E. Novel Brain-Penetrating Single Chain Antibodies Directed Against 3RTau for the Treatment of Alzheimer's Disease and Related Dementias. Methods in Molecular Biology (Clifton, N.J.). 2383: 447-457. PMID 34766306 DOI: 10.1007/978-1-0716-1752-6_28  0.113
2017 Fields JA, Metcalf J, Overk C, Adame A, Spencer B, Wrasidlo W, Florio J, Rockenstein E, He JJ, Masliah E. The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration. Journal of Neurovirology. PMID 28105557 DOI: 10.1007/S13365-016-0502-Z  0.106
2014 Overk CR, Cartier A, Shaked G, Rockenstein E, Ubhi K, Spencer B, Price DL, Patrick C, Desplats P, Masliah E. Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies. Molecular Neurodegeneration. 9: 18. PMID 24885390 DOI: 10.1186/1750-1326-9-18  0.101
2014 Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Gonzalez T, Desplats P, Michael SE, Trejo-Morales M, Overk CR, Masliah E. Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation. Journal of Alzheimer's Disease : Jad. 39: 583-600. PMID 24240640 DOI: 10.3233/Jad-131589  0.1
2016 Wrasidlo W, Tsigelny IF, Price DL, Dutta G, Rockenstein E, Schwarz TC, Ledolter K, Bonhaus D, Paulino A, Eleuteri S, Skjevik ÅA, Kouznetsova VL, Spencer B, Desplats P, Gonzalez-Ruelas T, ... ... Overk CR, et al. A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease. Brain : a Journal of Neurology. PMID 27679481 DOI: 10.1093/Brain/Aww238  0.099
2024 Iba M, Kwon S, Kim C, Szabo M, Horan-Portelance L, Lopez-Ocasio M, Dagur P, Overk C, Rissman RA, Masliah E. Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease. Journal of Neuroinflammation. 21: 93. PMID 38622654 DOI: 10.1186/s12974-024-03087-7  0.098
2023 Iba M, Kim C, Kwon S, Szabo M, Horan-Portelance L, Peer CJ, Figg WD, Reed X, Ding J, Lee SJ, Rissman RA, Cookson MR, Overk C, Wrasidlo W, Masliah E. Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD. Science Translational Medicine. 15: eabq6089. PMID 37163617 DOI: 10.1126/scitranslmed.abq6089  0.096
2013 Lashuel HA, Overk CR, Oueslati A, Masliah E. The many faces of α-synuclein: from structure and toxicity to therapeutic target. Nature Reviews. Neuroscience. 14: 38-48. PMID 23254192 DOI: 10.1038/Nrn3406  0.094
2015 Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Overk C, Gonzalez T, Trejo M, Spencer B, Kosberg K, Masliah E. Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions. Acs Chemical Neuroscience. 6: 403-16. PMID 25561023 DOI: 10.1021/Cn500332W  0.088
2020 Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32975365 DOI: 10.1002/alz.12185  0.087
2018 Hassen GW, Kesner L, Stracher A, Shulman A, Rockenstein E, Mante M, Adame A, Overk C, Rissman RA, Masliah E. Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies. Scientific Reports. 8: 18083. PMID 30591714 DOI: 10.1038/S41598-018-35729-1  0.083
2017 Overk C, Rockenstein E, Valera E, Stefanova N, Wenning G, Masliah E. Multiple system atrophy: experimental models and reality. Acta Neuropathologica. PMID 29058121 DOI: 10.1007/S00401-017-1772-0  0.082
2017 Rockenstein E, Ostroff G, Dikengil F, Rus F, Mante M, Florio J, Adame A, Trinh I, Kim C, Overk C, Masliah E, Rissman RA. Combined active humoral and cellular immunization approaches for the treatment of Synucleinopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29246926 DOI: 10.1523/Jneurosci.1170-17.2017  0.082
2014 Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, et al. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain : a Journal of Neurology. 137: 1496-513. PMID 24662516 DOI: 10.1093/Brain/Awu057  0.08
2016 Fields JA, Overk C, Adame A, Florio J, Mante M, Pineda A, Desplats P, Rockenstein E, Achim C, Masliah E. Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity. Journal of Neuroinflammation. 13: 120. PMID 27220536 DOI: 10.1186/S12974-016-0585-8  0.08
2014 Wrasidlo W, Crews LA, Tsigelny IF, Stocking E, Kouznetsova VL, Price D, Paulino A, Gonzales T, Overk CR, Patrick C, Rockenstein E, Masliah E. Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. British Journal of Pharmacology. 171: 5757-73. PMID 25117211 DOI: 10.1111/Bph.12875  0.078
2014 Nuber S, Tadros D, Fields J, Overk CR, Ettle B, Kosberg K, Mante M, Rockenstein E, Trejo M, Masliah E. Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD. Acta Neuropathologica. 127: 477-94. PMID 24509835 DOI: 10.1007/S00401-014-1255-5  0.077
2017 El-Agnaf O, Overk C, Rockenstein E, Mante M, Florio J, Adame A, Vaikath N, Majbour N, Lee SJ, Kim C, Masliah E, Rissman RA. Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy. Neurobiology of Disease. PMID 28476636 DOI: 10.1016/J.Nbd.2017.05.002  0.074
2011 Kelley CM, Perez SE, Overk CR, Wynick D, Mufson EJ. Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice. Journal of Alzheimer's Disease : Jad. 25: 491-504. PMID 21471639 DOI: 10.3233/Jad-2011-102097  0.073
2015 Rockenstein E, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Bisquert A, Trejo-Morales M, Spencer B, Masliah E. A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies. Plos One. 10: e0121570. PMID 25803611 DOI: 10.1371/Journal.Pone.0121570  0.072
2014 Overk CR, Masliah E. Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease. Biochemical Pharmacology. 88: 508-16. PMID 24462903 DOI: 10.1016/J.Bcp.2014.01.015  0.072
2018 Overk C, Masliah E. Dale Schenk One Year Anniversary: Fighting to Preserve the Memories. Journal of Alzheimer's Disease : Jad. 62: 1-13. PMID 29439357 DOI: 10.3233/Jad-171071  0.071
2023 Fares MB, Alijevic O, Johne S, Overk C, Hashimoto M, Kondylis A, Adame A, Dulize R, Peric D, Nury C, Battey J, Guedj E, Sierro N, Mc Hugh D, Rockenstein E, et al. Nicotine-mediated effects in neuronal and mouse models of synucleinopathy. Frontiers in Neuroscience. 17: 1239009. PMID 37719154 DOI: 10.3389/fnins.2023.1239009  0.069
2016 Price DL, Rockenstein E, Mante M, Adame A, Overk C, Spencer B, Duong-Polk KX, Bonhaus D, Lindsey J, Masliah E. Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson's Disease/Dementia with Lewy Bodies. Scientific Reports. 6: 29523. PMID 27389831 DOI: 10.1038/Srep29523  0.061
2019 Mackiewicz MM, Overk C, Achim CL, Masliah E. Pathogenesis of age-related HIV neurodegeneration. Journal of Neurovirology. PMID 30790184 DOI: 10.1007/S13365-019-00728-Z  0.06
2016 Spencer B, Desplats PA, Overk CR, Valera-Martin E, Rissman RA, Wu C, Mante M, Adame A, Florio J, Rockenstein E, Masliah E. Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7971-84. PMID 27466341 DOI: 10.1523/Jneurosci.0775-16.2016  0.059
2020 Iba M, Kim C, Sallin M, Kwon S, Verma A, Overk C, Rissman RA, Sen R, Sen JM, Masliah E. Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models. Journal of Neuroinflammation. 17: 214. PMID 32680537 DOI: 10.1186/S12974-020-01888-0  0.058
2009 Overk CR, Kelley CM, Mufson EJ. Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 35: 415-25. PMID 19524671 DOI: 10.1016/J.Nbd.2009.06.004  0.056
2023 Overk C, Fiorini E, Babolin C, Vukicevic M, Morici C, Madani R, Eligert V, Kosco-Vilbois M, Roberts A, Becker A, Pfeifer A, Mobley WC. Modeling Alzheimer's disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior. Frontiers in Neuroscience. 17: 1202208. PMID 37449271 DOI: 10.3389/fnins.2023.1202208  0.053
2019 Mandler M, Rockenstein E, Overk C, Mante M, Florio J, Adame A, Kim C, Santic R, Schneeberger A, Mattner F, Schmidhuber S, Galabova G, Spencer B, Masliah E, Rissman RA. Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31378574 DOI: 10.1016/J.Jalz.2019.02.002  0.052
2015 Overk CR, Rockenstein E, Florio J, Cheng Q, Masliah E. Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506. Neuroscience. 310: 549-60. PMID 26341908 DOI: 10.1016/J.Neuroscience.2015.08.068  0.049
2018 Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. Journal of Alzheimer's Disease : Jad. 61: 1201-1219. PMID 29332037 DOI: 10.3233/Jad-170388  0.048
2021 Sawa M, Overk C, Becker A, Derse D, Albay R, Weldy K, Salehi A, Beach TG, Doran E, Head E, Yu YE, Mobley WC. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34757693 DOI: 10.1002/alz.12463  0.048
2017 Spencer B, Valera E, Rockenstein E, Overk C, Mante M, Adame A, Zago W, Seubert P, Barbour R, Schenk D, Games D, Rissman RA, Masliah E. Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy. Acta Neuropathologica Communications. 5: 7. PMID 28086964 DOI: 10.1186/S40478-016-0410-8  0.039
2016 de Wilde MC, Overk CR, Sijben JW, Masliah E. Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26776762 DOI: 10.1016/J.Jalz.2015.12.005  0.036
2008 Overk CR, Oh K, Perez SE, Mufson EJ. P1-051: Brainstem Alzheimer's disease-like neuropathology in triple transgenic mice Alzheimer's & Dementia. 4: T220-T221. DOI: 10.1016/j.jalz.2008.05.637  0.035
2019 Terry N, Masliah A, Overk C, Masliah E. Remembering Robert D. Terry at a Time of Change in the World of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31282421 DOI: 10.3233/Jad-190518  0.03
2019 Overk C, Masliah E. Could changing the course of Alzheimer's disease pathology with immunotherapy prevent dementia? Brain : a Journal of Neurology. 142: 1853-1855. PMID 31505546 DOI: 10.1093/Brain/Awz165  0.025
2015 de Wilde MC, Overk C, Sijben JW, Masliah E. P2-181: Synapse and synaptic marker loss in Alzheimer's disease progression: Meta-analysis and systematic review of human studies Alzheimer's & Dementia. 11: P561-P561. DOI: 10.1016/J.Jalz.2015.06.720  0.023
2017 Overk C, Masliah E. Perspective on the calcium dyshomeostasis hypothesis in the pathogenesis of selective neuronal degeneration in animal models of AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28130011 DOI: 10.1016/J.Jalz.2017.01.005  0.017
2008 Oh K, Overk CR, Perez SE, Mufson EJ. P1-025: Intraneuronal Tau immunoreactivity is fixation dependent in young 3xTg-AD mice Alzheimer's & Dementia. 4: T212-T213. DOI: 10.1016/j.jalz.2008.05.610  0.015
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