| Year |
Citation |
Score |
| 2020 |
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, ... ... Sheppard D, et al. Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Science Translational Medicine. 12. PMID 32817366 DOI: 10.1126/Scitranslmed.Aay8798 |
0.328 |
|
| 2020 |
Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nature Communications. 11: 1920. PMID 32317643 DOI: 10.1038/S41467-020-15647-5 |
0.365 |
|
| 2019 |
Del Cid JS, Isik Reed N, Molnar K, Liu S, Dang B, Jensen SA, DeGrado W, Handford PA, Sheppard D, Sundaram AB. A disease associated mutation in fibrillin-1 differentially regulates integrin mediated cell adhesion. The Journal of Biological Chemistry. PMID 31640988 DOI: 10.1074/Jbc.Ra119.011109 |
0.348 |
|
| 2018 |
Fong V, Hsu A, Wu E, Looney AP, Ganesan P, Ren X, Sheppard D, Wicher SA, Thompson MA, Britt RD, Prakash YS, Bhattacharya M. Arhgef12 drives IL17A-induced airway contractility and airway hyperresponsiveness in mice. Jci Insight. 3. PMID 30385725 DOI: 10.1172/Jci.Insight.123578 |
0.355 |
|
| 2018 |
Podolsky MJ, Gupta D, Ha A, Ta R, Khalifeh-Soltani A, McKleroy W, Datta R, Sheppard D, Atabai K. Cell Division Cycle 7-Kinase is a negative regulator of cell-mediated collagen degradation. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29792348 DOI: 10.1152/Ajplung.00144.2018 |
0.347 |
|
| 2017 |
Tsujino K, Li JT, Tsukui T, Ren X, Bakiri L, Wagner EF, Sheppard D. Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00062.2017. PMID 28818870 DOI: 10.1152/Ajplung.00062.2017 |
0.392 |
|
| 2017 |
Kim KK, Sheppard D, Chapman HA. TGF-β1 Signaling and Tissue Fibrosis. Cold Spring Harbor Perspectives in Biology. PMID 28432134 DOI: 10.1101/Cshperspect.A022293 |
0.328 |
|
| 2017 |
Chang Y, Lau WL, Jo H, Tsujino K, Gewin L, Reed NI, Atakilit A, Nunes AC, DeGrado WF, Sheppard D. Pharmacologic Blockade of αvβ1 Integrin Ameliorates Renal Failure and Fibrosis In Vivo. Journal of the American Society of Nephrology : Jasn. PMID 28220032 DOI: 10.1681/Asn.2015050585 |
0.322 |
|
| 2016 |
Sundaram A, Chen C, Khalifeh-Soltani A, Atakilit A, Ren X, Qiu W, Jo H, DeGrado W, Huang X, Sheppard D. Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma. The Journal of Clinical Investigation. PMID 27918306 DOI: 10.1172/Jci88555 |
0.367 |
|
| 2016 |
Tsujino K, Reed NI, Atakilit A, Ren X, Sheppard D. Transforming Growth Factor β plays divergent roles in modulating vascular remodeling, inflammation and pulmonary fibrosis in a murine model of scleroderma. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00428.2016. PMID 27864286 DOI: 10.1152/Ajplung.00428.2016 |
0.387 |
|
| 2016 |
Meliopoulos VA, Van de Velde LA, Van de Velde NC, Karlsson EA, Neale G, Vogel P, Guy C, Sharma S, Duan S, Surman SL, Jones BG, Johnson MD, Bosio C, Jolly L, Jenkins RG, ... ... Sheppard D, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. Plos Pathogens. 12: e1005804. PMID 27505057 DOI: 10.1371/Journal.Ppat.1005804 |
0.36 |
|
| 2016 |
McAleer JP, Nguyen NL, Chen K, Kumar P, Ricks DM, Binnie M, Armentrout RA, Pociask DA, Hein A, Yu A, Vikram A, Bibby K, Umesaki Y, Rivera A, Sheppard D, et al. Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome. Journal of Immunology (Baltimore, Md. : 1950). PMID 27217583 DOI: 10.4049/Jimmunol.1502566 |
0.333 |
|
| 2016 |
Reboldi A, Arnon TI, Rodda LB, Atakilit A, Sheppard D, Cyster JG. IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches. Science (New York, N.Y.). 352: aaf4822. PMID 27174992 DOI: 10.1126/Science.Aaf4822 |
0.326 |
|
| 2016 |
Sun KH, Chang Y, Reed NI, Sheppard D. αSMA is an inconsistent marker of fibroblasts responsible for force dependent TGFβ activation or collagen production across multiple models of organ fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00350.2015. PMID 26944089 DOI: 10.1152/Ajplung.00350.2015 |
0.388 |
|
| 2016 |
Mohammed J, Beura LK, Bobr A, Astry B, Chicoine B, Kashem SW, Welty NE, Igyártó BZ, Wijeyesinghe S, Thompson EA, Matte C, Bartholin L, Kaplan A, Sheppard D, Bridges AG, et al. Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β. Nature Immunology. PMID 26901152 DOI: 10.1038/Ni.3396 |
0.357 |
|
| 2015 |
Peng ZW, Ikenaga N, Liu SB, Sverdlov DY, Vaid KA, Dixit R, Weinreb PH, Violette S, Sheppard D, Schuppan D, Popov Y. Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis and tumorigenesis. Hepatology (Baltimore, Md.). PMID 26448099 DOI: 10.1002/Hep.28274 |
0.354 |
|
| 2015 |
Li JT, Melton AC, Su G, Hamm DE, LaFemina M, Howard J, Fang X, Bhat S, Huynh KM, O'Kane CM, Ingram RJ, Muir RR, McAuley DF, Matthay MA, Sheppard D. Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome. Journal of Immunology (Baltimore, Md. : 1950). 195: 87-95. PMID 26002979 DOI: 10.4049/Jimmunol.1500054 |
0.324 |
|
| 2015 |
Reed NI, Jo H, Chen C, Tsujino K, Arnold TD, DeGrado WF, Sheppard D. The αvβ1 integrin plays a critical in vivo role in tissue fibrosis. Science Translational Medicine. 7: 288ra79. PMID 25995225 DOI: 10.1126/Scitranslmed.Aaa5094 |
0.383 |
|
| 2015 |
Sheppard D. Epithelial-mesenchymal interactions in fibrosis and repair. Transforming growth factor-β activation by epithelial cells and fibroblasts. Annals of the American Thoracic Society. 12: S21-3. PMID 25830829 DOI: 10.1513/Annalsats.201406-245Mg |
0.374 |
|
| 2014 |
Xu P, Bailey-Bucktrout S, Xi Y, Xu D, Du D, Zhang Q, Xiang W, Liu J, Melton A, Sheppard D, Chapman HA, Bluestone JA, Derynck R. Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling. Molecular Cell. 56: 723-37. PMID 25526531 DOI: 10.1016/J.Molcel.2014.11.027 |
0.351 |
|
| 2014 |
Bhattacharya M, Sundaram A, Kudo M, Farmer J, Ganesan P, Khalifeh-Soltani A, Arjomandi M, Atabai K, Huang X, Sheppard D. IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction. The Journal of Clinical Investigation. 124: 4895-8. PMID 25271629 DOI: 10.1172/Jci76658 |
0.348 |
|
| 2014 |
Erle DJ, Sheppard D. The cell biology of asthma. The Journal of Cell Biology. 205: 621-31. PMID 24914235 DOI: 10.1083/Jcb.201401050 |
0.369 |
|
| 2014 |
Ito K, Morimoto J, Kihara A, Matsui Y, Kurotaki D, Kanayama M, Simmons S, Ishii M, Sheppard D, Takaoka A, Uede T. Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. Proceedings of the National Academy of Sciences of the United States of America. 111: 3080-5. PMID 24516133 DOI: 10.1073/Pnas.1311022111 |
0.338 |
|
| 2014 |
Madala SK, Korfhagen TR, Schmidt S, Davidson C, Edukulla R, Ikegami M, Violette SM, Weinreb PH, Sheppard D, Hardie WD. Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L726-35. PMID 24508732 DOI: 10.1152/Ajplung.00357.2013 |
0.377 |
|
| 2014 |
Travis MA, Sheppard D. TGF-β activation and function in immunity. Annual Review of Immunology. 32: 51-82. PMID 24313777 DOI: 10.1146/Annurev-Immunol-032713-120257 |
0.319 |
|
| 2013 |
Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, ... ... Sheppard D, et al. Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nature Medicine. 19: 1617-24. PMID 24216753 DOI: 10.1038/Nm.3282 |
0.625 |
|
| 2013 |
Su G, Atakilit A, Li JT, Wu N, Luong J, Chen R, Bhattacharya M, Sheppard D. Effective treatment of mouse sepsis with an inhibitory antibody targeting integrin αvβ5. Critical Care Medicine. 41: 546-53. PMID 23263571 DOI: 10.1097/Ccm.0B013E3182711B1E |
0.352 |
|
| 2013 |
Henderson NC, Sheppard D. Integrin-mediated regulation of TGFβ in fibrosis. Biochimica Et Biophysica Acta. 1832: 891-6. PMID 23046811 DOI: 10.1016/J.Bbadis.2012.10.005 |
0.35 |
|
| 2013 |
Henderson N, Arnold T, Katamura Y, Giacomini M, Rodriguez J, McCarty J, Ruminski P, Griggs D, Maher J, Iredale J, Lacy-Hulbert A, Adams R, Sheppard D. OC-002 Selective Alpha V Integrin Deletion Identifies a Core, Targetable Molecular Pathway that Regulates Fibrosis Across Solid Organs Gut. 62. DOI: 10.1136/Gutjnl-2013-304907.002 |
0.388 |
|
| 2012 |
Freimuth J, Clermont FF, Huang X, DeSapio A, Tokuyasu TA, Sheppard D, Akhurst RJ. Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus. Proceedings of the National Academy of Sciences of the United States of America. 109: 18042-7. PMID 23064636 DOI: 10.1073/Pnas.1205374109 |
0.324 |
|
| 2012 |
Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, et al. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 109: 16354-9. PMID 22988107 DOI: 10.1073/Pnas.1214596109 |
0.353 |
|
| 2012 |
Chen C, Kudo M, Rutaganira F, Takano H, Lee C, Atakilit A, Robinett KS, Uede T, Wolters PJ, Shokat KM, Huang X, Sheppard D. Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing. The Journal of Clinical Investigation. 122: 2916-27. PMID 22772469 DOI: 10.1172/Jci60387 |
0.326 |
|
| 2012 |
Thornton EE, Looney MR, Bose O, Sen D, Sheppard D, Locksley R, Huang X, Krummel MF. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. The Journal of Experimental Medicine. 209: 1183-99. PMID 22585735 DOI: 10.1084/Jem.20112667 |
0.658 |
|
| 2012 |
Bhattacharya M, Su G, Su X, Oses-Prieto JA, Li JT, Huang X, Hernandez H, Atakilit A, Burlingame AL, Matthay MA, Sheppard D. IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L12-9. PMID 22561460 DOI: 10.1152/Ajplung.00375.2011 |
0.375 |
|
| 2012 |
Kudo M, Melton AC, Chen C, Engler MB, Huang KE, Ren X, Wang Y, Bernstein X, Li JT, Atabai K, Huang X, Sheppard D. IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nature Medicine. 18: 547-54. PMID 22388091 DOI: 10.1038/Nm.2684 |
0.326 |
|
| 2012 |
Doherty TA, Khorram N, Sugimoto K, Sheppard D, Rosenthal P, Cho JY, Pham A, Miller M, Croft M, Broide DH. Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness. Journal of Immunology (Baltimore, Md. : 1950). 188: 2622-9. PMID 22327070 DOI: 10.4049/Jimmunol.1101632 |
0.414 |
|
| 2012 |
Giacomini MM, Travis MA, Kudo M, Sheppard D. Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force. Experimental Cell Research. 318: 716-22. PMID 22309779 DOI: 10.1016/J.Yexcr.2012.01.020 |
0.652 |
|
| 2012 |
Sugimoto K, Kudo M, Sundaram A, Ren X, Huang K, Bernstein X, Wang Y, Raymond WW, Erle DJ, Abrink M, Caughey GH, Huang X, Sheppard D. The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. The Journal of Clinical Investigation. 122: 748-58. PMID 22232213 DOI: 10.1172/JCI58815 |
0.31 |
|
| 2012 |
Su G, Atakilit A, Li JT, Wu N, Bhattacharya M, Zhu J, Shieh JE, Li E, Chen R, Sun S, Su CP, Sheppard D. Absence of integrin αvβ3 enhances vascular leak in mice by inhibiting endothelial cortical actin formation. American Journal of Respiratory and Critical Care Medicine. 185: 58-66. PMID 21980034 DOI: 10.1164/Rccm.201108-1381Oc |
0.334 |
|
| 2011 |
Tatler AL, John AE, Jolly L, Habgood A, Porte J, Brightling C, Knox AJ, Pang L, Sheppard D, Huang X, Jenkins G. Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma Journal of Immunology. 187: 6094-6107. PMID 22025551 DOI: 10.4049/Jimmunol.1003507 |
0.38 |
|
| 2011 |
Katsumoto TR, Violette SM, Sheppard D. Blocking TGFβ via Inhibition of the αvβ6 Integrin: A Possible Therapy for Systemic Sclerosis Interstitial Lung Disease. International Journal of Rheumatology. 2011: 208219. PMID 22013449 DOI: 10.1155/2011/208219 |
0.339 |
|
| 2011 |
Munger JS, Sheppard D. Cross talk among TGF-β signaling pathways, integrins, and the extracellular matrix. Cold Spring Harbor Perspectives in Biology. 3: a005017. PMID 21900405 DOI: 10.1101/Cshperspect.A005017 |
0.334 |
|
| 2011 |
Kon S, Atakilit A, Sheppard D. Short form of α9 promotes α9β1 integrin-dependent cell adhesion by modulating the function of the full-length α9 subunit. Experimental Cell Research. 317: 1774-84. PMID 21515257 DOI: 10.1016/J.Yexcr.2011.04.005 |
0.322 |
|
| 2011 |
Nishimichi N, Hayashita-Kinoh H, Chen C, Matsuda H, Sheppard D, Yokosaki Y. Osteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1. The Journal of Biological Chemistry. 286: 11170-8. PMID 21321126 DOI: 10.1074/Jbc.M110.189258 |
0.331 |
|
| 2011 |
Tatler A, John A, Habgood A, Porte J, Jolly L, Knox A, Huang X, Sheppard D, Jenkins G. Loss/inhibition of aVb5 integrin reduces allergen-induced increases in airway smooth muscle thickness in in vivo models of asthma F1000research. 2. DOI: 10.7490/F1000Research.1089693.1 |
0.316 |
|
| 2010 |
Hogmalm A, Sheppard D, Lappalainen U, Bry K. beta6 Integrin subunit deficiency alleviates lung injury in a mouse model of bronchopulmonary dysplasia. American Journal of Respiratory Cell and Molecular Biology. 43: 88-98. PMID 19717813 DOI: 10.1165/Rcmb.2008-0480Oc |
0.353 |
|
| 2009 |
Atabai K, Jame S, Azhar N, Kuo A, Lam M, McKleroy W, Dehart G, Rahman S, Xia DD, Melton AC, Wolters P, Emson CL, Turner SM, Werb Z, Sheppard D. Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. The Journal of Clinical Investigation. 119: 3713-22. PMID 19884654 DOI: 10.1172/Jci40053 |
0.387 |
|
| 2009 |
Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T. Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Developmental Cell. 17: 175-86. PMID 19686679 DOI: 10.1016/J.Devcel.2009.06.017 |
0.301 |
|
| 2009 |
Grassinger J, Haylock DN, Storan MJ, Haines GO, Williams B, Whitty GA, Vinson AR, Be CL, Li S, Sørensen ES, Tam PP, Denhardt DT, Sheppard D, Choong PF, Nilsson SK. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood. 114: 49-59. PMID 19417209 DOI: 10.1182/Blood-2009-01-197988 |
0.312 |
|
| 2009 |
Xu MY, Porte J, Knox AJ, Weinreb PH, Maher TM, Violette SM, McAnulty RJ, Sheppard D, Jenkins G. Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q). The American Journal of Pathology. 174: 1264-79. PMID 19147812 DOI: 10.2353/Ajpath.2009.080160 |
0.385 |
|
| 2009 |
Singh P, Chen C, Pal-Ghosh S, Stepp MA, Sheppard D, Van De Water L. Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. The Journal of Investigative Dermatology. 129: 217-28. PMID 18633440 DOI: 10.1038/Jid.2008.201 |
0.322 |
|
| 2008 |
deHart GW, Jin T, McCloskey DE, Pegg AE, Sheppard D. The alpha9beta1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 105: 7188-93. PMID 18480266 DOI: 10.1073/Pnas.0708044105 |
0.304 |
|
| 2008 |
Sheppard D. Dust mites' dirty dealings with dendritic cells. Nature Medicine. 14: 487-8. PMID 18463654 DOI: 10.1038/Nm0508-487 |
0.311 |
|
| 2008 |
Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang-Hoover J, Aiba M, Sheppard D, Pereira L. Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production. The American Journal of Pathology. 172: 1127-40. PMID 18349127 DOI: 10.2353/Ajpath.2008.070448 |
0.383 |
|
| 2008 |
Ganter MT, Roux J, Miyazawa B, Howard M, Frank JA, Su G, Sheppard D, Violette SM, Weinreb PH, Horan GS, Matthay MA, Pittet JF. Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms. Circulation Research. 102: 804-12. PMID 18276918 DOI: 10.1161/Circresaha.107.161067 |
0.343 |
|
| 2008 |
Muro AF, Moretti FA, Moore BB, Yan M, Atrasz RG, Wilke CA, Flaherty KR, Martinez FJ, Tsui JL, Sheppard D, Baralle FE, Toews GB, White ES. An essential role for fibronectin extra type III domain A in pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 177: 638-45. PMID 18096707 DOI: 10.1164/Rccm.200708-1291Oc |
0.373 |
|
| 2008 |
Horan GS, Wood S, Ona V, Li DJ, Lukashev ME, Weinreb PH, Simon KJ, Hahm K, Allaire NE, Rinaldi NJ, Goyal J, Feghali-Bostwick CA, Matteson EL, O'Hara C, Lafyatis R, ... ... Sheppard D, et al. Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation. American Journal of Respiratory and Critical Care Medicine. 177: 56-65. PMID 17916809 DOI: 10.1164/Rccm.200706-805Oc |
0.377 |
|
| 2007 |
Araya J, Cambier S, Markovics JA, Wolters P, Jablons D, Hill A, Finkbeiner W, Jones K, Broaddus VC, Sheppard D, Barzcak A, Xiao Y, Erle DJ, Nishimura SL. Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. The Journal of Clinical Investigation. 117: 3551-62. PMID 17965775 DOI: 10.1172/Jci32526 |
0.399 |
|
| 2007 |
Koth LL, Alex B, Hawgood S, Nead MA, Sheppard D, Erle DJ, Morris DG. Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1. American Journal of Respiratory Cell and Molecular Biology. 37: 651-9. PMID 17641300 DOI: 10.1165/Rcmb.2006-0428Oc |
0.382 |
|
| 2007 |
Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, ... ... Sheppard D, et al. Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. The American Journal of Pathology. 170: 110-25. PMID 17200187 DOI: 10.2353/Ajpath.2007.060158 |
0.316 |
|
| 2007 |
Su G, Hodnett M, Wu N, Atakilit A, Kosinski C, Godzich M, Huang XZ, Kim JK, Frank JA, Matthay MA, Sheppard D, Pittet JF. Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function. American Journal of Respiratory Cell and Molecular Biology. 36: 377-86. PMID 17079779 DOI: 10.1165/Rcmb.2006-0238Oc |
0.362 |
|
| 2006 |
Chen C, Huang X, Atakilit A, Zhu QS, Corey SJ, Sheppard D. The Integrin alpha9beta1 contributes to granulopoiesis by enhancing granulocyte colony-stimulating factor receptor signaling. Immunity. 25: 895-906. PMID 17137800 DOI: 10.1016/J.Immuni.2006.10.013 |
0.3 |
|
| 2006 |
Rao H, Lu G, Kajiya H, Garcia-Palacios V, Kurihara N, Anderson J, Patrene K, Sheppard D, Blair HC, Windle JJ, Choi SJ, Roodman GD. Alpha9beta1: a novel osteoclast integrin that regulates osteoclast formation and function. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 1657-65. PMID 16995821 DOI: 10.1359/Jbmr.060718 |
0.31 |
|
| 2006 |
Chen C, Huang X, Sheppard D. ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice. Molecular and Cellular Biology. 26: 6950-6. PMID 16943435 DOI: 10.1128/Mcb.00646-06 |
0.346 |
|
| 2006 |
Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proceedings of the National Academy of Sciences of the United States of America. 103: 13180-5. PMID 16924102 DOI: 10.1073/Pnas.0605669103 |
0.401 |
|
| 2006 |
Neurohr C, Nishimura SL, Sheppard D. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. American Journal of Respiratory Cell and Molecular Biology. 35: 252-9. PMID 16574941 DOI: 10.1165/Rcmb.2006-0013Oc |
0.334 |
|
| 2005 |
Sheppard D. Integrin-mediated activation of latent transforming growth factor beta. Cancer Metastasis Reviews. 24: 395-402. PMID 16258727 DOI: 10.1007/S10555-005-5131-6 |
0.371 |
|
| 2005 |
Atabai K, Fernandez R, Huang X, Ueki I, Kline A, Li Y, Sadatmansoori S, Smith-Steinhart C, Zhu W, Pytela R, Werb Z, Sheppard D. Mfge8 is critical for mammary gland remodeling during involution. Molecular Biology of the Cell. 16: 5528-37. PMID 16195353 DOI: 10.1091/Mbc.E05-02-0128 |
0.598 |
|
| 2005 |
Ludlow A, Yee KO, Lipman R, Bronson R, Weinreb P, Huang X, Sheppard D, Lawler J. Characterization of integrin β6 and thrombospondin‐1 double‐null mice Journal of Cellular and Molecular Medicine. 9: 421-437. PMID 15963261 DOI: 10.1111/J.1582-4934.2005.Tb00367.X |
0.324 |
|
| 2005 |
Roux J, Kawakatsu H, Gartland B, Pespeni M, Sheppard D, Matthay MA, Canessa CM, Pittet JF. Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway. The Journal of Biological Chemistry. 280: 18579-89. PMID 15755725 DOI: 10.1074/Jbc.M410561200 |
0.34 |
|
| 2005 |
Bates RC, Bellovin DI, Brown C, Maynard E, Wu B, Kawakatsu H, Sheppard D, Oettgen P, Mercurio AM. Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma. The Journal of Clinical Investigation. 115: 339-47. PMID 15668738 DOI: 10.1172/Jci23183 |
0.316 |
|
| 2005 |
Lane NE, Yao W, Nakamura MC, Humphrey MB, Kimmel D, Huang X, Sheppard D, Ross FP, Teitelbaum SL. Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 58-66. PMID 15619670 DOI: 10.1359/Jbmr.041017 |
0.308 |
|
| 2005 |
Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, ... ... Sheppard D, et al. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. American Journal of Respiratory and Critical Care Medicine. 171: 563-70. PMID 15557128 DOI: 10.1164/Rccm.200409-1286Oc |
0.305 |
|
| 2004 |
Chen C, Young BA, Coleman CS, Pegg AE, Sheppard D. Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration. The Journal of Cell Biology. 167: 161-70. PMID 15479742 DOI: 10.1083/Jcb.200312166 |
0.343 |
|
| 2004 |
Sheppard D. Roles of alphav integrins in vascular biology and pulmonary pathology. Current Opinion in Cell Biology. 16: 552-7. PMID 15363806 DOI: 10.1016/J.Ceb.2004.06.017 |
0.384 |
|
| 2004 |
Williams CH, Kajander T, Hyypiä T, Jackson T, Sheppard D, Stanway G. Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9. Journal of Virology. 78: 6967-73. PMID 15194773 DOI: 10.1128/Jvi.78.13.6967-6973.2004 |
0.348 |
|
| 2004 |
Bazan-Socha S, Kisiel DG, Young B, Theakston RD, Calvete JJ, Sheppard D, Marcinkiewicz C. Structural requirements of MLD-containing disintegrins for functional interaction with alpha 4 beta 1 and alpha 9 beta1 integrins. Biochemistry. 43: 1639-47. PMID 14769041 DOI: 10.1021/Bi035853T |
0.324 |
|
| 2003 |
Tomczuk M, Takahashi Y, Huang J, Murase S, Mistretta M, Klaffky E, Sutherland A, Bolling L, Coonrod S, Marcinkiewicz C, Sheppard D, Stepp MA, White JM. Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3. Experimental Cell Research. 290: 68-81. PMID 14516789 DOI: 10.1016/S0014-4827(03)00307-0 |
0.343 |
|
| 2003 |
Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. The Journal of Biological Chemistry. 278: 43939-50. PMID 12930837 DOI: 10.1074/Jbc.M304882200 |
0.356 |
|
| 2003 |
Sheppard D. Functions of pulmonary epithelial integrins: from development to disease. Physiological Reviews. 83: 673-86. PMID 12843406 DOI: 10.1152/Physrev.00033.2002 |
0.308 |
|
| 2003 |
Morris DG, Huang X, Kaminski N, Wang Y, Shapiro SD, Dolganov G, Glick A, Sheppard D. Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature. 422: 169-73. PMID 12634787 DOI: 10.1038/Nature01413 |
0.391 |
|
| 2002 |
Sheppard D. Endothelial integrins and angiogenesis: not so simple anymore. The Journal of Clinical Investigation. 110: 913-4. PMID 12370267 DOI: 10.1172/Jci16713 |
0.33 |
|
| 2002 |
Knight PA, Wright SH, Brown JK, Huang X, Sheppard D, Miller HR. Enteric expression of the integrin alpha(v)beta(6) is essential for nematode-induced mucosal mast cell hyperplasia and expression of the granule chymase, mouse mast cell protease-1. The American Journal of Pathology. 161: 771-9. PMID 12213704 DOI: 10.1016/S0002-9440(10)64236-8 |
0.408 |
|
| 2002 |
Kuperman DA, Huang X, Koth LL, Chang GH, Dolganov GM, Zhu Z, Elias JA, Sheppard D, Erle DJ. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nature Medicine. 8: 885-9. PMID 12091879 DOI: 10.1038/Nm734 |
0.309 |
|
| 2002 |
Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben-Dor A, Lollini L, Morris D, Kim Y, DeLustro B, Sheppard D, Pardo A, Selman M, Heller RA. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 99: 6292-7. PMID 11983918 DOI: 10.1073/Pnas.092134099 |
0.349 |
|
| 2002 |
Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. The Journal of Cell Biology. 157: 149-60. PMID 11927607 DOI: 10.1083/Jcb.200109079 |
0.316 |
|
| 2002 |
Sheppard D. Killed by leukocytes that don't know when to leave Nature Immunology. 3: 337-338. PMID 11919573 DOI: 10.1038/Ni0402-337 |
0.367 |
|
| 2002 |
Mitchell Lecture RS, Sheppard D. Uses of expression microarrays in studies of pulmonary fibrosis, asthma, acute lung injury, and emphysema Chest. 121. PMID 11893658 DOI: 10.1378/Chest.121.3_Suppl.21S-A |
0.387 |
|
| 2002 |
Liao Y, Gotwals PJ, Koteliansky VE, Sheppard D, Water LVD. The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing. Journal of Biological Chemistry. 277: 14467-14474. PMID 11839764 DOI: 10.1074/Jbc.M201100200 |
0.333 |
|
| 2002 |
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO, Hodivala-Dilke KM. Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nature Medicine. 8: 27-34. PMID 11786903 DOI: 10.1038/Nm0102-27 |
0.304 |
|
| 2002 |
Jackson T, Mould AP, Sheppard D, King AM. Integrin alphavbeta1 is a receptor for foot-and-mouth disease virus. Journal of Virology. 76: 935-41. PMID 11773368 DOI: 10.1128/Jvi.76.3.935-941.2002 |
0.31 |
|
| 2001 |
Lee JH, Kaminski N, Dolganov G, Grunig G, Koth L, Solomon C, Erie DJ, Sheppard D. Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types American Journal of Respiratory Cell and Molecular Biology. 25: 474-485. PMID 11694453 DOI: 10.1165/Ajrcmb.25.4.4522 |
0.364 |
|
| 2001 |
Ljubimov AV, Saghizadeh M, Pytela R, Sheppard D, Kenney MC. Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas Journal of Histochemistry and Cytochemistry. 49: 1341-1350. PMID 11668187 DOI: 10.1177/002215540104901102 |
0.316 |
|
| 2001 |
Sheppard D. Integrin-mediated activation of transforming growth factor-β1 in pulmonary fibrosis Chest. 120. PMID 11451914 DOI: 10.1378/Chest.120.1_Suppl.S49 |
0.426 |
|
| 2001 |
Thomas GJ, Lewis MP, Whawell SA, Russell A, Sheppard D, Hart IR, Speight PM, Marshall JF. Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells. The Journal of Investigative Dermatology. 117: 67-73. PMID 11442751 DOI: 10.1046/J.0022-202X.2001.01379.X |
0.321 |
|
| 2001 |
Sheppard D. Pulmonary fibrosis: A cellular overreaction or a failure of communication? Journal of Clinical Investigation. 107: 1501-1502. PMID 11413155 DOI: 10.1172/Jci13318 |
0.395 |
|
| 2001 |
Miller LC, Blakemore W, Sheppard D, Atakilit A, King AM, Jackson T. Role of the cytoplasmic domain of the beta-subunit of integrin alpha(v)beta6 in infection by foot-and-mouth disease virus. Journal of Virology. 75: 4158-64. PMID 11287565 DOI: 10.1128/Jvi.75.9.4158-4164.2001 |
0.31 |
|
| 2000 |
Eto K, Puzon-McLaughlin W, Sheppard D, Sehara-Fujisawa A, Zhang XP, Takada Y. RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction Journal of Biological Chemistry. 275: 34922-34930. PMID 10944520 DOI: 10.1074/Jbc.M001953200 |
0.323 |
|
| 2000 |
Sheppard D. In vivo functions of integrins: Lessons from null mutations in mice Matrix Biology. 19: 203-209. PMID 10936445 DOI: 10.1016/S0945-053X(00)00065-2 |
0.335 |
|
| 2000 |
Marcinkiewicz C, Taooka Y, Yokosaki Y, Calvete JJ, Marcinkiewicz MM, Lobb RR, Niewiarowski S, Sheppard D. Inhibitory Effects of MLDG-containing Heterodimeric Disintegrins Reveal Distinct Structural Requirements for Interaction of the Integrin α9β1 with VCAM-1, Tenascin-C, and Osteopontin Journal of Biological Chemistry. 275: 31930-31937. PMID 10926928 DOI: 10.1074/Jbc.M003209200 |
0.345 |
|
| 2000 |
Huang XZ, Wu JF, Ferrando R, Lee JH, Wang YL, Farese RV, Sheppard D. Fatal Bilateral Chylothorax in Mice Lacking the Integrin α9β1 Molecular and Cellular Biology. 20: 5208-5215. PMID 10866676 DOI: 10.1128/Mcb.20.14.5208-5215.2000 |
0.378 |
|
| 2000 |
Takahashi H, Isobe T, Horibe S, Takagi J, Yokosaki Y, Sheppard D, Saito Y. Tissue transglutaminase, coagulation factor XIII, and the pro-polypeptide of von Willebrand factor are all ligands for the integrins alpha 9beta 1 and alpha 4beta 1. The Journal of Biological Chemistry. 275: 23589-95. PMID 10816592 DOI: 10.1074/Jbc.M003526200 |
0.356 |
|
| 2000 |
Jackson T, Sheppard D, Denyer M, Blakemore W, King AM. The epithelial integrin alphavbeta6 is a receptor for foot-and-mouth disease virus. Journal of Virology. 74: 4949-56. PMID 10799568 DOI: 10.1128/Jvi.74.11.4949-4956.2000 |
0.346 |
|
| 2000 |
Kaminski N, Allard JD, Pittet JF, Zuo F, Griffiths MJD, Morris D, Huang X, Sheppard D, Heller RA. Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis Proceedings of the National Academy of Sciences of the United States of America. 97: 1778-1783. PMID 10677534 DOI: 10.1073/Pnas.97.4.1778 |
0.349 |
|
| 2000 |
Huang X, Griffiths M, Wu J, Farese RV, Sheppard D. Normal Development, Wound Healing, and Adenovirus Susceptibility in β5-Deficient Mice Molecular and Cellular Biology. 20: 755-759. PMID 10629031 DOI: 10.1128/Mcb.20.3.755-759.2000 |
0.333 |
|
| 1999 |
Yokosaki Y, Matsuura N, Sasaki T, Murakami I, Schneider H, Higashiyama S, Saitoh Y, Yamakido M, Taooka Y, Sheppard D. The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. Journal of Biological Chemistry. 274: 36328-36334. PMID 10593924 DOI: 10.1074/Jbc.274.51.36328 |
0.316 |
|
| 1999 |
Taooka Y, Chen J, Yednock T, Sheppard D. The Integrin α9β1 Mediates Adhesion to Activated Endothelial Cells and Transendothelial Neutrophil Migration through Interaction with Vascular Cell Adhesion Molecule-1 Journal of Cell Biology. 145: 413-420. PMID 10209034 DOI: 10.1083/Jcb.145.2.413 |
0.355 |
|
| 1999 |
Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, Matthay MA, Rifkin DB, Sheppard D. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 96: 319-28. PMID 10025398 DOI: 10.1016/S0092-8674(00)80545-0 |
0.322 |
|
| 1999 |
Roger P, Puchelle E, Bajolet-Laudinat O, Tournier J-, Debordeaux C, Plotkowski M-, Cohen JHM, Sheppard D, Bentzmann SD. Fibronectin and alpha5beta1 integrin mediate binding of Pseudomonas aeruginosa to repairing airway epithelium European Respiratory Journal. 13: 1301-1309. DOI: 10.1034/J.1399-3003.1999.13F14.X |
0.37 |
|
| 1998 |
Desloges N, Basora N, Perreault N, Bouatrouss Y, Sheppard D, Beaulieu JF. Regulated expression of the integrin alpha9beta1 in the epithelium of the developing human gut and in intestinal cell lines: relation with cell proliferation. Journal of Cellular Biochemistry. 71: 536-45. PMID 9827699 DOI: 10.1002/(Sici)1097-4644(19981215)71:4<536::Aid-Jcb8>3.0.Co;2-1 |
0.341 |
|
| 1998 |
Huang X, Wu J, Zhu W, Pytela R, Sheppard D. Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice American Journal of Respiratory Cell and Molecular Biology. 19: 636-642. PMID 9761761 DOI: 10.1165/Ajrcmb.19.4.3293 |
0.413 |
|
| 1998 |
Sheppard D. Airway epithelial integrins: Why so many? American Journal of Respiratory Cell and Molecular Biology. 19: 349-351. PMID 9730861 DOI: 10.1165/Ajrcmb.19.3.F144 |
0.373 |
|
| 1998 |
Schneider H, Harbottle RP, Yokosaki Y, Kunde J, Sheppard D, Coutelle C. A novel peptide, PLAEIDGIELTY, for the targeting of α9β1-integrins Febs Letters. 429: 269-273. PMID 9662430 DOI: 10.1016/S0014-5793(98)00612-7 |
0.302 |
|
| 1998 |
Yokosaki Y, Matsuura N, Higashiyama S, Murakami I, Obara M, Yamakido M, Shigeto N, Chen J, Sheppard D. Identification of the Ligand Binding Site for the Integrin α9β1 in the Third Fibronectin Type III Repeat of Tenascin-C Journal of Biological Chemistry. 273: 11423-11428. PMID 9565552 DOI: 10.1074/Jbc.273.19.11423 |
0.31 |
|
| 1998 |
Basora N, Desloges N, Chang Q, Bouatrouss Y, Gosselin J, Poisson J, Sheppard D, Beaulieu JF. Expression of the alpha9beta1 integrin in human colonic epithelial cells: resurgence of the fetal phenotype in a subset of colon cancers and adenocarcinoma cell lines. International Journal of Cancer. 75: 738-43. PMID 9495242 DOI: 10.1002/(Sici)1097-0215(19980302)75:5<738::Aid-Ijc12>3.0.Co;2-2 |
0.351 |
|
| 1998 |
Basora N, Desloges N, Perreault N, Bouatrouss Y, Sheppard D, Beaulieu J. Expression of the integrin α9β1 in the epithelium of the developing human gut and in intestinal cell lines: Relationship will cell proliferation Gastroenterology. 114: A865. DOI: 10.1016/S0016-5085(98)83525-7 |
0.308 |
|
| 1998 |
Corry DB, Grünig G, Hadeiba H, Kurup VP, Warnock ML, Sheppard D, Rennick DM, Locksley RM. Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice Molecular Medicine. 4: 344-355. DOI: 10.1007/Bf03401741 |
0.359 |
|
| 1998 |
Desloges N, Basora N, Perreault N, Bouatrouss Y, Sheppard D, Beaulieu JF. Regulated expression of the integrin alpha9beta1 in the epithelium of the developing human gut and in intestinal cell lines: relation with cell proliferation. Journal of Cellular Biochemistry. 71: 536-545. DOI: 10.1002/(Sici)1097-4644(19981215)71:4<536::Aid-Jcb8>3.3.Co;2-T |
0.341 |
|
| 1997 |
Agrez MV, Shafren DR, Gu X, Cox K, Sheppard D, Barry RD. Integrin αvβ6 Enhances Coxsackievirus B1 Lytic Infection of Human Colon Cancer Cells Virology. 239: 71-77. PMID 9426447 DOI: 10.1006/Viro.1997.8831 |
0.325 |
|
| 1997 |
Ramos DM, Chen BL, Boylen K, Stern M, Kramer RH, Sheppard D, Nishimura SL, Greenspan D, Zardi L, Pytela R. Stromal fibroblasts influence oral squamous-cell carcinoma cell interactions with tenascin-C. International Journal of Cancer. Journal International Du Cancer. 72: 369-76. PMID 9219848 DOI: 10.1002/(Sici)1097-0215(19970717)72:2<369::Aid-Ijc28>3.0.Co;2-9 |
0.327 |
|
| 1996 |
Chen J, Maeda T, Sekiguchi K, Sheppard D. Distinct Structural Requirements for Interaction of the Integrins α5β1, αvβ5, and αvβ6 with the Central Cell Binding Domain in Fibronectin Cell Adhesion and Communication. 4: 237-250. PMID 9117344 DOI: 10.3109/15419069609010769 |
0.314 |
|
| 1996 |
Herard AL, Pierrot D, Hinnrasky J, Kaplan H, Sheppard D, Puchelle E, Zahm JM. Fibronectin and its alpha 5 beta 1-integrin receptor are involved in the wound-repair process of airway epithelium. American Journal of Physiology-Lung Cellular and Molecular Physiology. 271. PMID 8944715 DOI: 10.1152/Ajplung.1996.271.5.L726 |
0.332 |
|
| 1996 |
Wang A, Yokosaki Y, Ferrando R, Balmes J, Sheppard D. Differential regulation of airway epithelial integrins by growth factors. American Journal of Respiratory Cell and Molecular Biology. 15: 664-672. PMID 8918373 DOI: 10.1165/Ajrcmb.15.5.8918373 |
0.332 |
|
| 1996 |
Smith LL, Cheung HK, Lingg LE, Chen J, Sheppard D, Pytela R, Giachelli CM. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by α9β1 integrin Journal of Biological Chemistry. 271: 28485-28491. PMID 8910476 DOI: 10.1074/Jbc.271.45.28485 |
0.323 |
|
| 1996 |
Dixit RB, Chen A, Chen J, Sheppard D. Identification of a sequence within the integrin beta6 subunit cytoplasmic domain that is required to support the specific effect of alphavbeta6 on proliferation in three-dimensional culture. The Journal of Biological Chemistry. 271: 25976-80. PMID 8824234 DOI: 10.1074/Jbc.271.42.25976 |
0.339 |
|
| 1996 |
Yokosaki Y, Monis H, Chen J, Sheppard D. Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains. Journal of Biological Chemistry. 271: 24144-24150. PMID 8798654 DOI: 10.1074/Jbc.271.39.24144 |
0.378 |
|
| 1996 |
Huang XZ, Wu JF, Cass D, Erle DJ, Corry D, Young SG, Farese RV, Sheppard D. Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin. The Journal of Cell Biology. 133: 921-8. PMID 8666675 DOI: 10.1083/Jcb.133.4.921 |
0.389 |
|
| 1996 |
Haapasalmi K, Zhang K, Tonnesen M, Olerud J, Sheppard D, Salo T, Kramer R, Clark RA, Uitto VJ, Larjava H. Keratinocytes in human wounds express alpha v beta 6 integrin. The Journal of Investigative Dermatology. 106: 42-8. PMID 8592080 DOI: 10.1111/1523-1747.Ep12327199 |
0.321 |
|
| 1995 |
Wang A, Patrone L, McDonald JA, Sheppard D. Expression of the integrin subunit α9 in the murine embryo Developmental Dynamics. 204: 421-431. PMID 8601035 DOI: 10.1002/Aja.1002040408 |
0.306 |
|
| 1995 |
Huang X, Chen A, Agrez M, Sheppard D. A point mutation in the integrin beta 6 subunit abolishes both alpha v beta 6 binding to fibronectin and receptor localization to focal contacts. American Journal of Respiratory Cell and Molecular Biology. 13: 245-251. PMID 7626292 DOI: 10.1165/Ajrcmb.13.2.7626292 |
0.338 |
|
| 1995 |
Boylan AM, Sanan DA, Sheppard D, Broaddus VC. Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta 5. The Journal of Clinical Investigation. 96: 1987-2001. PMID 7560092 DOI: 10.1172/Jci118246 |
0.309 |
|
| 1995 |
Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, Pytela R. The Human Integrin α8β1 Functions as a Receptor for Tenascin, Fibronectin, and Vitronectin Journal of Biological Chemistry. 270: 23196-23202. PMID 7559467 DOI: 10.1074/Jbc.270.39.23196 |
0.364 |
|
| 1995 |
Weinacker A, Ferrando R, Elliott M, Hogg J, Balmes J, Sheppard D. Distribution of integrins alpha v beta 6 and alpha 9 beta 1 and their known ligands, fibronectin and tenascin, in human airways. American Journal of Respiratory Cell and Molecular Biology. 12: 547-556. PMID 7537970 DOI: 10.1165/Ajrcmb.12.5.7537970 |
0.33 |
|
| 1995 |
Stepp MA, Zhu L, Sheppard D, Cranfill RL. Localized distribution of α9 integrin in the cornea and changes in expression during corneal epithelial cell differentiation Journal of Histochemistry and Cytochemistry. 43: 353-362. PMID 7534781 DOI: 10.1177/43.4.7534781 |
0.316 |
|
| 1994 |
Breuss JM, Gillett N, Lu L, Sheppard D, Pytela R. Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 1521-7. PMID 8245410 DOI: 10.1177/41.10.8245410 |
0.311 |
|
| 1994 |
Cone RI, Weinacker A, Chen A, Sheppard D. Effects of beta subunit cytoplasmic domain deletions on the recruitment of the integrin alpha v beta 6 to focal contacts. Cell Adhesion and Communication. 2: 101-13. PMID 8081887 DOI: 10.3109/15419069409004430 |
0.353 |
|
| 1994 |
Agrez M, Chen A, Cone RI, Pytela R, Sheppard D. The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain. The Journal of Cell Biology. 127: 547-56. PMID 7929593 DOI: 10.1083/Jcb.127.2.547 |
0.351 |
|
| 1993 |
Sheppard D. Identification and characterization of novel airway epithelial integrins American Review of Respiratory Disease. 148. PMID 8256923 DOI: 10.1164/Ajrccm/148.6_Pt_2.S38 |
0.406 |
|
| 1993 |
Palmer EL, Rüegg C, Ferrando R, Pytela R, Sheppard D. Sequence and tissue distribution of the integrin α9 subunit, a novel partner β1 that is widely distributed in epithelia and muscle Journal of Cell Biology. 123: 1289-1297. PMID 8245132 DOI: 10.1083/Jcb.123.5.1289 |
0.329 |
|
| 1991 |
Gordon T, Balmes J, Fine J, Sheppard D. Airway oedema and obstruction in guinea pigs exposed to inhaled endotoxin. British Journal of Industrial Medicine. 48: 629-35. PMID 1911406 DOI: 10.1136/Oem.48.9.629 |
0.323 |
|
| 1991 |
Erle DJ, Sheppard D, Breuss J, Rüegg C, Pytela R. Novel integrin α and β subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction American Journal of Respiratory Cell and Molecular Biology. 5: 170-177. PMID 1892648 DOI: 10.1165/Ajrcmb/5.2.170 |
0.369 |
|
| 1988 |
Gordon T, Thompson JE, Sheppard D. Arachidonic acid metabolites do not mediate toluene diisocyanate-induced airway hyperresponsiveness in Guinea pigs Prostaglandins. 35: 699-706. PMID 2840688 DOI: 10.1016/0090-6980(88)90143-8 |
0.302 |
|
| 1988 |
Sheppard D. Mechanisms of acute increases in airway responsiveness caused by environmental chemicals The Journal of Allergy and Clinical Immunology. 81: 128-132. PMID 2828449 DOI: 10.1016/0091-6749(88)90231-X |
0.325 |
|
| 1988 |
Sheppard D, Scypinski L. A tachykinin receptor antagonist inhibits and an inhibitor of tachykinin metabolism potentiates toluene diisocyanate-induced airway hyperresponsiveness in guinea pigs American Review of Respiratory Disease. 138: 547-551. PMID 2462379 DOI: 10.1164/Ajrccm/138.3.547 |
0.302 |
|
| 1987 |
Gordon T, Milligan SA, Levin J, Thompson JE, Fine JM, Sheppard D. Apparent effect of catalase on airway edema in guinea pigs. Role of endotoxin contamination. The American Review of Respiratory Disease. 135: 854-9. PMID 3032030 DOI: 10.1164/Arrd.1987.135.4.854 |
0.302 |
|
| 1987 |
Thompson JE, Scypinski LA, Gordon T, Sheppard D. Tachykinins mediate the acute increase in airway responsiveness caused by toluene diisocyanate in guinea pigs The American Review of Respiratory Disease. 136: 43-49. PMID 2440357 DOI: 10.1164/Ajrccm/136.1.43 |
0.306 |
|
| 1986 |
Sheppard D, Distefano S, Morse L, Becker C. Acute effects of routine firefighting on lung function. American Journal of Industrial Medicine. 9: 333-340. PMID 3518426 DOI: 10.1002/Ajim.4700090404 |
0.324 |
|
| 1986 |
Thompson JE, Scypinski LA, Gordon T, Sheppard D. Hydroxyurea inhibits airway hyperresponsiveness in guinea pigs by a granulocyte-independent mechanism. The American Review of Respiratory Disease. 134: 1213-1218. PMID 3024538 DOI: 10.1164/Arrd.1986.134.5.1213 |
0.327 |
|
| 1986 |
Sheppard D, DiStefano S, Byrd RC, Eschenbacher WL, Bell V, Steck J, Laddu A. Effects of esmolol on airway function in patients with asthma. Journal of Clinical Pharmacology. 26: 169-74. PMID 2870080 DOI: 10.1002/J.1552-4604.1986.Tb02929.X |
0.305 |
|
| 1985 |
Gordon T, Sheppard D, McDonald DM, Distefano S, Scypinski L. Airway hyperresponsiveness and inflammation induced by toluene diisocyanate in guinea pigs. The American Review of Respiratory Disease. 132: 1106-1112. PMID 2998244 DOI: 10.1164/Arrd.1985.132.5.1106 |
0.316 |
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