Edith C. Glazer, Ph.D. - Publications

Affiliations: 
2003 University of California, San Diego, La Jolla, CA 
Area:
Organic Chemistry

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mitchell RJ, Kriger SM, Fenton AD, Havrylyuk D, Pandeya A, Sun Y, Smith T, DeRouchey JE, Unrine JM, Oza V, Blackburn JS, Wei Y, Heidary DK, Glazer EC. A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin. Rsc Chemical Biology. 4: 344-353. PMID 37181632 DOI: 10.1039/d2cb00247g  0.354
2022 Ryan RT, Hachey AC, Stevens K, Parkin SR, Mitchell RJ, Selegue JP, Heidary DK, Glazer EC. Synthesis and photobiological evaluation of Ru(II) complexes with expanded chelate polypyridyl ligands. Journal of Inorganic Biochemistry. 238: 112031. PMID 36327501 DOI: 10.1016/j.jinorgbio.2022.112031  0.417
2021 Ryan RT, Havrylyuk D, Stevens KC, Moore LH, Parkin S, Blackburn JS, Heidary DK, Selegue JP, Glazer EC. Biological Investigations of Ru(II) Complexes With Diverse β-diketone Ligands. European Journal of Inorganic Chemistry. 2021: 3611-3621. PMID 34539235 DOI: 10.1002/ejic.202100468  0.396
2021 Hachey AC, Havrylyuk D, Glazer EC. Biological activities of polypyridyl-type ligands: implications for bioinorganic chemistry and light-activated metal complexes. Current Opinion in Chemical Biology. 61: 191-202. PMID 33799087 DOI: 10.1016/j.cbpa.2021.01.016  0.369
2021 Zamora A, Wachter E, Vera M, Heidary DK, Rodríguez V, Ortega E, Fernández-Espín V, Janiak C, Glazer EC, Barone G, Ruiz J. Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences. Inorganic Chemistry. PMID 33502194 DOI: 10.1021/acs.inorgchem.0c02648  0.66
2020 Ryan RT, Havrylyuk D, Stevens KC, Moore LH, Kim DY, Blackburn JS, Heidary DK, Selegue JP, Glazer EC. Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents. Dalton Transactions (Cambridge, England : 2003). PMID 32845256 DOI: 10.1039/D0Dt02016H  0.488
2020 Havrylyuk D, Heidary DK, Sun Y, Parkin S, Glazer EC. Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy. Acs Omega. 5: 18894-18906. PMID 32775891 DOI: 10.1021/acsomega.0c02079  0.464
2020 Ryan RT, Stevens KC, Calabro R, Parkin S, Mahmoud J, Kim DY, Heidary DK, Glazer EC, Selegue JP. Bis-tridentate N-Heterocyclic Carbene Ru(II) Complexes are Promising New Agents for Photodynamic Therapy. Inorganic Chemistry. PMID 32530274 DOI: 10.1021/Acs.Inorgchem.0C00686  0.514
2020 Havrylyuk D, Stevens K, Parkin S, Glazer EC. Toward Optimal Ru(II) Photocages: Balancing Photochemistry, Stability, and Biocompatibility Through Fine Tuning of Steric, Electronic, and Physiochemical Features. Inorganic Chemistry. PMID 31899619 DOI: 10.1021/Acs.Inorgchem.9B02065  0.429
2019 Roque J, Havrylyuk D, Barrett PC, Sainuddin T, McCain J, Colón K, Sparks WT, Bradner E, Monro S, Heidary D, Cameron C, Glazer EC, McFarland S. Strained, Photoejecting Ru(II) Complexes that are Cytotoxic Under Hypoxic Conditions. Photochemistry and Photobiology. PMID 31691282 DOI: 10.1111/Php.13174  0.503
2018 Havrylyuk D, Deshpande M, Parkin S, Glazer EC. Ru(ii) complexes with diazine ligands: electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents. Chemical Communications (Cambridge, England). PMID 30338772 DOI: 10.1039/C8Cc05809A  0.501
2018 Havrylyuk D, Howerton BS, Nease L, Parkin S, Heidary DK, Glazer EC. Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines. European Journal of Medicinal Chemistry. 156: 790-799. PMID 30055464 DOI: 10.1016/J.Ejmech.2018.04.044  0.496
2018 Sun Y, Heidary DK, Zhang Z, Richards CI, Glazer EC. Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes. Molecular Pharmaceutics. PMID 29865789 DOI: 10.1021/Acs.Molpharmaceut.8B00407  0.409
2017 Havrylyuk D, Heidary DK, Nease L, Parkin S, Glazer EC. Photochemical Properties and Structure-Activity Relationships of RuII Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents. European Journal of Inorganic Chemistry. 2017: 1687-1694. PMID 29200939 DOI: 10.1002/Ejic.201601450  0.5
2017 Kohler L, Nease L, Vo P, Garofolo J, Heidary DK, Thummel RP, Glazer EC. Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands. Inorganic Chemistry. PMID 28949518 DOI: 10.1021/Acs.Inorgchem.7B01642  0.534
2017 Glazer EC. Panchromatic Osmium Complexes for Photodynamic Therapy: Solutions to Existing Problems and New Questions. Photochemistry and Photobiology. PMID 28543667 DOI: 10.1111/Php.12796  0.389
2017 Zamora A, Denning CA, Heidary DK, Wachter E, Nease LA, Ruiz J, Glazer EC. Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage. Dalton Transactions (Cambridge, England : 2003). PMID 28121322 DOI: 10.1039/C6Dt04405K  0.626
2017 Havrylyuk D, Heidary DK, Nease L, Parkin S, Glazer EC. Back Cover: Photochemical Properties and Structure-Activity Relationships of RuII Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents (Eur. J. Inorg. Chem. 12/2017) European Journal of Inorganic Chemistry. 2017: 1842-1842. DOI: 10.1002/Ejic.201700259  0.471
2016 Wachter E, Moyá D, Glazer EC. Combining a Ru(II) "Building Block" and Rapid Screening Approach to Identify DNA Structure-Selective "Light Switch" Compounds. Acs Combinatorial Science. PMID 28029775 DOI: 10.1021/Acscombsci.6B00119  0.67
2016 Wachter E, Zamora A, Heidary DK, Ruiz J, Glazer EC. Geometry matters: inverse cytotoxic relationship for cis/trans-Ru(ii) polypyridyl complexes from cis/trans-[PtCl2(NH3)2]. Chemical Communications (Cambridge, England). PMID 27352966 DOI: 10.1039/C6Cc04813G  0.656
2016 Wachter E, Glazer EC, Parkin S, Brock CP. An exceptional 5:4 enantiomeric structure. Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials. 72: 223-31. PMID 27048724 DOI: 10.1107/S205252061600127X  0.592
2016 Dickerson M, Howerton B, Bae Y, Glazer E. Light-Sensitive Ruthenium Complex-Loaded Cross-linked Polymeric Nanoassemblies for the Treatment of Cancer. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 4: 394-408. PMID 26855780 DOI: 10.1039/C5Tb01613D  0.432
2016 Wachter E, Moyá D, Parkin S, Glazer EC. Ruthenium Complex "Light Switches" that are Selective for Different G-Quadruplex Structures. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 550-9. PMID 26560887 DOI: 10.1002/Chem.201503203  0.69
2016 Glazer EC. Abstract 4840: The role of the metal scaffold in the development of cytotoxic metal complexes Cancer Research. 76: 4840-4840. DOI: 10.1158/1538-7445.Am2016-4840  0.356
2016 Magde D, Magde MD, Glazer EC. So-called "dual emission" for 3MLCT luminescence in ruthenium complex ions: What is really happening? Coordination Chemistry Reviews. 306: 447-467. DOI: 10.1016/J.Ccr.2015.01.003  0.331
2015 Wachter E, Moyá D, Parkin S, Glazer EC. Inside Back Cover: Ruthenium Complex “Light Switches” that are Selective for Different G-Quadruplex Structures (Chem. Eur. J. 2/2016) Chemistry - a European Journal. 22: 819-819. DOI: 10.1002/Chem.201504856  0.644
2014 Heidary DK, Howerton BS, Glazer EC. Coordination of hydroxyquinolines to a ruthenium bis-dimethyl-phenanthroline scaffold radically improves potency for potential as antineoplastic agents. Journal of Medicinal Chemistry. 57: 8936-46. PMID 25314373 DOI: 10.1021/Jm501043S  0.417
2014 Dickerson M, Sun Y, Howerton B, Glazer EC. Modifying charge and hydrophilicity of simple Ru(II) polypyridyl complexes radically alters biological activities: old complexes, surprising new tricks. Inorganic Chemistry. 53: 10370-7. PMID 25249443 DOI: 10.1021/Ic5013796  0.431
2014 Hidayatullah AN, Wachter E, Heidary DK, Parkin S, Glazer EC. Photoactive Ru(II) complexes with dioxinophenanthroline ligands are potent cytotoxic agents. Inorganic Chemistry. 53: 10030-2. PMID 25198057 DOI: 10.1021/Ic5017164  0.706
2014 Wachter E, Glazer EC. Mechanistic study on the photochemical "light switch" behavior of [Ru(bpy)2dmdppz]2+. The Journal of Physical Chemistry. A. 118: 10474-86. PMID 25058448 DOI: 10.1021/Jp504249A  0.716
2014 Heidary DK, Glazer EC. A light-activated metal complex targets both DNA and RNA in a fluorescent in vitro transcription and translation assay. Chembiochem : a European Journal of Chemical Biology. 15: 507-11. PMID 24482049 DOI: 10.1002/Cbic.201300681  0.393
2014 Wachter E, Howerton BS, Hall EC, Parkin S, Glazer EC. A new type of DNA "light-switch": a dual photochemical sensor and metalating agent for duplex and G-quadruplex DNA. Chemical Communications (Cambridge, England). 50: 311-3. PMID 24226814 DOI: 10.1039/C3Cc47269H  0.673
2013 Glazer EC. Light-activated metal complexes that covalently modify DNA Israel Journal of Chemistry. 53: 391-400. DOI: 10.1002/Ijch.201300019  0.42
2012 Wachter E, Heidary DK, Howerton BS, Parkin S, Glazer EC. Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window. Chemical Communications (Cambridge, England). 48: 9649-51. PMID 22908094 DOI: 10.1039/C2Cc33359G  0.709
2012 Howerton BS, Heidary DK, Glazer EC. Strained ruthenium complexes are potent light-activated anticancer agents. Journal of the American Chemical Society. 134: 8324-7. PMID 22553960 DOI: 10.1021/Ja3009677  0.472
2007 Glazer EC, Magde D, Tor Y. Ruthenium complexes that break the rules: structural features controlling dual emission. Journal of the American Chemical Society. 129: 8544-51. PMID 17571887 DOI: 10.1021/Ja071124F  0.584
2006 Jouvenot D, Glazer EC, Tor Y. Photodimerizable ditopic ligand. Organic Letters. 8: 1987-90. PMID 16671763 DOI: 10.1021/Ol060253I  0.74
2005 Glazer EC, Magde D, Tor Y. Dual emission from a family of conjugated dinuclear Ru(II) complexes. Journal of the American Chemical Society. 127: 4190-2. PMID 15783199 DOI: 10.1021/Ja0440304  0.593
2005 Glazer EC, Belyea B, Tor Y. A simple synthesis of isotopically pure 2,2′-dipyridyl-d8 Inorganic Chemistry Communications. 8: 517-519. DOI: 10.1016/J.Inoche.2005.03.011  0.466
2004 Aldrich-Wright J, Brodie C, Glazer EC, Luedtke NW, Elson-Schwab L, Tor Y. Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+. Chemical Communications (Cambridge, England). 1018-9. PMID 15069523 DOI: 10.1039/B316917K  0.749
2004 Aldrich-Wright J, Brodie C, Glazer EC, Luedtke NW, Elson-Schwab L, Tor Y. Symmetrical dinuclear complexes with high DNA affinity based on Ru(dpq)2(phen)2+ Chemical Communications. 10: 1018-1019.  0.742
2003 Brodie CR, Aldrich-Wright JR, Glazer E, Luedtke N, Tor Y. Synthesis and DNA binding of bisintercalating complexes of the type [(dpq)2Ru(phen-n-SOS-n-phen)Ru(dpq)2]4+ Journal of Inorganic Biochemistry. 96: 105. DOI: 10.1016/S0162-0134(03)80572-X  0.713
2002 Glazer EC, Tor Y. RuII complexes of "large-surface" ligands. Angewandte Chemie (International Ed. in English). 41: 4022-6. PMID 12412069 DOI: 10.1002/1521-3773(20021104)41:21<4022::Aid-Anie4022>3.0.Co;2-1  0.616
2002 Luedtke NW, Hwang JS, Glazer EC, Gut D, Kol M, Tor Y. Eilatin Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the binding of RNA. Chembiochem : a European Journal of Chemical Biology. 3: 766-71. PMID 12203975 DOI: 10.1002/1439-7633(20020802)3:8<766::Aid-Cbic766>3.0.Co;2-X  0.698
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