208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Selhub J, Miller JW, Troen AM, Mason JB, Jacques PF. Perspective: The High-Folate-Low-Vitamin B-12 Interaction Is a Novel Cause of Vitamin B-12 Depletion with a Specific Etiology-A Hypothesis. Advances in Nutrition (Bethesda, Md.). PMID 34634124 DOI: 10.1093/advances/nmab106  0.344
2021 Liu CT, Karasik D, Xu H, Zhou Y, Broe K, Cupples LA, Cpgm de Groot L, Ham A, Hannan MT, Hsu YH, Jacques P, McLean RR, Paul L, Selhub J, Trajanoska K, et al. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density. The American Journal of Clinical Nutrition. PMID 33964857 DOI: 10.1093/ajcn/nqab093  0.35
2019 McGowan EC, Hong X, Selhub J, Paul L, Wood RA, Matsui EC, Keet CA, Wang X. Association Between Folate Metabolites and the Development of Food Allergy in Children. The Journal of Allergy and Clinical Immunology. in Practice. PMID 31252026 DOI: 10.1016/J.Jaip.2019.06.017  0.305
2019 Houghton SC, Eliassen AH, Zhang SM, Selhub J, Rosner BA, Willett WC, Hankinson SE. Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women. Breast Cancer Research and Treatment. PMID 30955184 DOI: 10.1007/S10549-019-05223-X  0.401
2019 Houghton SC, Eliassen AH, Zhang S, Selhub J, Rosner BA, Willett WC, Hankinson SE. Abstract 5042: Folate and other B-vitamins and the risk of breast cancer in younger women Cancer Research. 79: 5042-5042. DOI: 10.1158/1538-7445.Am2019-5042  0.375
2018 Steluti J, Reginaldo C, Selhub J, Paul L, Fisberg RM, Marchioni DM. Presence of circulating folic acid in plasma and its relation with dietary intake, vitamin B complex concentrations and genetic variants. European Journal of Nutrition. PMID 30390106 DOI: 10.1007/S00394-018-1852-5  0.441
2018 Houghton SC, Eliassen AH, Zhang SM, Selhub J, Rosner BA, Willett WC, Hankinson SE. Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folic acid fortification in the US. International Journal of Cancer. PMID 30346061 DOI: 10.1002/Ijc.31934  0.395
2018 Houghton SC, Eliassen AH, Zhang SM, Selhub J, Rosner BA, Willett WC, Hankinson SE. Abstract 3221: Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folic acid fortification in the US Cancer Research. 78: 3221-3221. DOI: 10.1158/1538-7445.Am2018-3221  0.406
2017 Kancherla V, Ibne Hasan MOS, Hamid R, Paul L, Selhub J, Oakley G, Quamruzzaman Q, Mazumdar M. Prenatal folic acid use associated with decreased risk of myelomeningocele: A case-control study offers further support for folic acid fortification in Bangladesh. Plos One. 12: e0188726. PMID 29190654 DOI: 10.1371/Journal.Pone.0188726  0.353
2017 Miranti EH, Stolzenberg-Solomon R, Weinstein SJ, Selhub J, Männistö S, Taylor PR, Freedman ND, Albanes D, Abnet CC, Murphy G. Low Vitamin B12 Increases Risk of Gastric Cancer: A Prospective Study of One-Carbon Metabolism Nutrients and Risk of Upper Gastrointestinal Tract Cancer. International Journal of Cancer. PMID 28568053 DOI: 10.1002/Ijc.30809  0.429
2017 Kanner J, Selhub J, Shpaizer A, Rabkin B, Shacham I, Tirosh O. Redox homeostasis in stomach medium by foods: The Postprandial Oxidative Stress Index (POSI) for balancing nutrition and human health. Redox Biology. 12: 929-936. PMID 28478382 DOI: 10.1016/J.Redox.2017.04.029  0.302
2017 Tauheed J, Sanchez-Guerra M, Lee JJ, Paul L, Ibne Hasan MO, Quamruzzaman Q, Selhub J, Wright RO, Christiani DC, Coull BA, Baccarelli AA, Mazumdar M. Associations between post translational histone modifications, myelomeningocele risk, environmental arsenic exposure, and folate deficiency among participants in a case control study in Bangladesh. Epigenetics. 0. PMID 28387569 DOI: 10.1080/15592294.2017.1312238  0.358
2016 Paul L, Selhub J. Interaction between excess folate and low vitamin B12 status. Molecular Aspects of Medicine. PMID 27876554 DOI: 10.1016/J.Mam.2016.11.004  0.417
2016 Ren J, Murphy G, Fan J, Dawsey SM, Taylor PR, Selhub J, Qiao Y, Abnet CC. Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China. Scientific Reports. 6: 35281. PMID 27748414 DOI: 10.1038/Srep35281  0.433
2016 Sawaengsri H, Bergethon PR, Qiu WQ, Scott TM, Jacques PF, Selhub J, Paul L. Transcobalamin 776C→G polymorphism is associated with peripheral neuropathy in elderly individuals with high folate intake. The American Journal of Clinical Nutrition. PMID 27733392 DOI: 10.3945/Ajcn.116.139030  0.465
2016 Chaudhari SN, Mukherjee M, Vagasi AS, Bi G, Rahman MM, Nguyen CQ, Paul L, Selhub J, Kipreos ET. Bacterial Folates Provide an Exogenous Signal for C. elegans Germline Stem Cell Proliferation. Developmental Cell. 38: 33-46. PMID 27404357 DOI: 10.1016/J.Devcel.2016.06.013  0.304
2016 Selhub J, Rosenberg IH. Excessive folic acid intake and relation to adverse health outcome. Biochimie. PMID 27131640 DOI: 10.1016/J.Biochi.2016.04.010  0.442
2016 Sawaengsri H, Wang J, Reginaldo C, Steluti J, Wu D, Meydani SN, Selhub J, Paul L. High folic acid intake reduces natural killer cell cytotoxicity in aged mice. The Journal of Nutritional Biochemistry. 30: 102-7. PMID 27012626 DOI: 10.1016/J.Jnutbio.2015.12.006  0.316
2016 Pentieva K, Selhub J, Paul L, Molloy AM, McNulty B, Ward M, Marshall B, Dornan J, Reilly R, Parle-McDermott A, Bradbury I, Ozaki M, Scott JM, McNulty H. Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood. The Journal of Nutrition. PMID 26817717 DOI: 10.3945/Jn.115.223644  0.359
2016 Miranti E, Stolzenberg-Solomon R, Weinstein S, Selhub J, Männistö S, Taylor PR, Freedman ND, Albanes D, Abnet C, Murphy G. Abstract 4301: Serum vitamin B12 and development of non-cardia gastric cancer: a prospective study Cancer Research. 76: 4301-4301. DOI: 10.1158/1538-7445.Am2016-4301  0.462
2015 Selhub J, Troen AM. Sulfur amino acids and atherosclerosis: a role for excess dietary methionine. Annals of the New York Academy of Sciences. PMID 26647293 DOI: 10.1111/Nyas.12962  0.458
2015 Cho E, Zhang X, Townsend MK, Selhub J, Paul L, Rosner B, Fuchs CS, Willett WC, Giovannucci EL. Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer. Journal of the National Cancer Institute. 107. PMID 26376686 DOI: 10.1093/Jnci/Djv260  0.374
2015 McMahon GM, Hwang SJ, Tanner RM, Jacques PF, Selhub J, Muntner P, Fox CS. The association between vitamin B12, albuminuria and reduced kidney function: an observational cohort study. Bmc Nephrology. 16: 7. PMID 25644490 DOI: 10.1186/1471-2369-16-7  0.429
2015 Paul L, Sawaengsri H, Reginaldo C, Selhub J. Effect of a High Folic Acid Diet on Telomere Length of Colonic Mucosa in Mice The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.Lb340  0.336
2014 Williams SR, Yang Q, Chen F, Liu X, Keene KL, Jacques P, Chen WM, Weinstein G, Hsu FC, Beiser A, Wang L, Bookman E, Doheny KF, Wolf PA, Zilka M, ... Selhub J, et al. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. Plos Genetics. 10: e1004214. PMID 24651765 DOI: 10.1371/Journal.Pgen.1004214  0.312
2013 Selhub J, Byun A, Liu Z, Mason JB, Bronson RT, Crott JW. Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease. The Journal of Nutritional Biochemistry. 24: 2138-43. PMID 24183308 DOI: 10.1016/J.Jnutbio.2013.08.005  0.46
2013 van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, ... ... Selhub J, et al. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. The American Journal of Clinical Nutrition. 98: 668-76. PMID 23824729 DOI: 10.3945/Ajcn.112.044545  0.319
2013 Paul L, Ueland PM, Selhub J. Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation. Nutrition Reviews. 71: 239-44. PMID 23550784 DOI: 10.1111/Nure.12014  0.465
2013 Je Y, Lee JE, Ma J, Zhang X, Cho E, Rosner B, Selhub J, Fuchs CS, Meyerhardt J, Giovannucci E. Prediagnostic plasma vitamin B6 (pyridoxal 5'-phosphate) and survival in patients with colorectal cancer. Cancer Causes & Control : Ccc. 24: 719-29. PMID 23340905 DOI: 10.1007/S10552-013-0152-X  0.363
2013 Mikael LG, Deng L, Paul L, Selhub J, Rozen R. Moderately high intake of folic acid has a negative impact on mouse embryonic development. Birth Defects Research. Part a, Clinical and Molecular Teratology. 97: 47-52. PMID 23125102 DOI: 10.1002/Bdra.23092  0.349
2012 Song Y, Manson JE, Lee IM, Cook NR, Paul L, Selhub J, Giovannucci E, Zhang SM. Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma. Journal of the National Cancer Institute. 104: 1562-75. PMID 23066166 DOI: 10.1093/Jnci/Djs370  0.476
2012 Morris MS, Selhub J, Jacques PF. Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study. Journal of the American Geriatrics Society. 60: 1457-64. PMID 22788704 DOI: 10.1111/J.1532-5415.2012.04076.X  0.435
2012 Moorthy D, Peter I, Scott TM, Parnell LD, Lai CQ, Crott JW, Ordovás JM, Selhub J, Griffith J, Rosenberg IH, Tucker KL, Troen AM. Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults. The Journal of Nutrition. 142: 1554-60. PMID 22739363 DOI: 10.3945/Jn.112.161828  0.332
2012 Orjuela MA, Cabrera-Muñoz L, Paul L, Ramirez-Ortiz MA, Liu X, Chen J, Mejia-Rodriguez F, Medina-Sanson A, Diaz-Carreño S, Suen IH, Selhub J, Ponce-Castañeda MV. Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake. Cancer. 118: 5912-9. PMID 22648968 DOI: 10.1002/Cncr.27621  0.334
2012 Sakakeeny L, Roubenoff R, Obin M, Fontes JD, Benjamin EJ, Bujanover Y, Jacques PF, Selhub J. Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults. The Journal of Nutrition. 142: 1280-5. PMID 22623384 DOI: 10.3945/Jn.111.153056  0.746
2012 Lee JE, Wei EK, Fuchs CS, Hunter DJ, Lee IM, Selhub J, Stampfer MJ, Willett WC, Ma J, Giovannucci E. Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies. Cancer Causes & Control : Ccc. 23: 537-45. PMID 22367721 DOI: 10.1007/S10552-012-9911-3  0.399
2012 Han SS, Sue LY, Berndt SI, Selhub J, Burdette LA, Rosenberg PS, Ziegler RG. Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 417-27. PMID 22253295 DOI: 10.1158/1055-9965.Epi-11-0782  0.329
2011 Selhub J, Paul L. Folic acid fortification: why not vitamin B12 also? Biofactors (Oxford, England). 37: 269-71. PMID 21674649 DOI: 10.1002/Biof.173  0.489
2011 Yetley EA, Pfeiffer CM, Phinney KW, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, Curtin LR, Durazo-Arvizu RA, Eckfeldt JH, Green R, Gregory JF, Hoofnagle AN, Jacobsen DW, ... ... Selhub J, et al. Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. The American Journal of Clinical Nutrition. 94: 313S-321S. PMID 21593512 DOI: 10.3945/Ajcn.111.013243  0.442
2011 Kalmbach R, Paul L, Selhub J. Determination of unmetabolized folic acid in human plasma using affinity HPLC. The American Journal of Clinical Nutrition. 94: 343S-347S. PMID 21593489 DOI: 10.3945/Ajcn.111.013433  0.349
2011 Zhang J, Handy DE, Wang Y, Bouchard G, Selhub J, Loscalzo J, Carey MC. Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice. Hepatology (Baltimore, Md.). 54: 697-706. PMID 21567442 DOI: 10.1002/Hep.24428  0.348
2011 Le Marchand L, Wang H, Selhub J, Vogt TM, Yokochi L, Decker R. Association of plasma vitamin B6 with risk of colorectal adenoma in a multiethnic case-control study. Cancer Causes & Control : Ccc. 22: 929-36. PMID 21437631 DOI: 10.1007/S10552-011-9759-Y  0.486
2011 Pickell L, Brown K, Li D, Wang XL, Deng L, Wu Q, Selhub J, Luo L, Jerome-Majewska L, Rozen R. High intake of folic acid disrupts embryonic development in mice. Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 8-19. PMID 21254354 DOI: 10.1002/Bdra.20754  0.37
2011 Murphy G, Fan JH, Mark SD, Dawsey SM, Selhub J, Wang J, Taylor PR, Qiao YL, Abnet CC. Prospective study of serum cysteine levels and oesophageal and gastric cancers in China. Gut. 60: 618-23. PMID 21242262 DOI: 10.1136/Gut.2010.225854  0.356
2011 Sempértegui F, Estrella B, Tucker KL, Hamer DH, Narvaez X, Sempértegui M, Griffiths JK, Noel SE, Dallal GE, Selhub J, Meydani SN. Metabolic syndrome in the elderly living in marginal peri-urban communities in Quito, Ecuador. Public Health Nutrition. 14: 758-67. PMID 20955641 DOI: 10.1017/S1368980010002636  0.438
2010 Selhub J, Troen A, Rosenberg IH. B vitamins and the aging brain. Nutrition Reviews. 68: S112-8. PMID 21091944 DOI: 10.1111/J.1753-4887.2010.00346.X  0.448
2010 Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, Meigs JB, Levy D, Wang TJ, Jacques PF, Benjamin EJ, Vasan RS. A multi-marker approach to predict incident CKD and microalbuminuria. Journal of the American Society of Nephrology : Jasn. 21: 2143-9. PMID 20966127 DOI: 10.1681/Asn.2010010085  0.345
2010 Velagaleti RS, Gona P, Larson MG, Wang TJ, Levy D, Benjamin EJ, Selhub J, Jacques PF, Meigs JB, Tofler GH, Vasan RS. Multimarker approach for the prediction of heart failure incidence in the community. Circulation. 122: 1700-6. PMID 20937976 DOI: 10.1161/Circulationaha.109.929661  0.323
2010 Gibson TM, Weinstein SJ, Mayne ST, Pfeiffer RM, Selhub J, Taylor PR, Virtamo J, Albanes D, Stolzenberg-Solomon R. A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma. Cancer Causes & Control : Ccc. 21: 1061-9. PMID 20383577 DOI: 10.1007/S10552-010-9534-5  0.414
2010 Page JH, Ma J, Chiuve SE, Stampfer MJ, Selhub J, Manson JE, Rimm EB. Plasma total cysteine and total homocysteine and risk of myocardial infarction in women: a prospective study. American Heart Journal. 159: 599-604. PMID 20362718 DOI: 10.1016/J.Ahj.2009.12.037  0.368
2010 Morris MS, Jacques PF, Rosenberg IH, Selhub J. Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. The American Journal of Clinical Nutrition. 91: 1733-44. PMID 20357042 DOI: 10.3945/Ajcn.2009.28671  0.371
2010 Lee JE, Jacques PF, Dougherty L, Selhub J, Giovannucci E, Zeisel SH, Cho E. Are dietary choline and betaine intakes determinants of total homocysteine concentration? The American Journal of Clinical Nutrition. 91: 1303-10. PMID 20219967 DOI: 10.3945/Ajcn.2009.28456  0.45
2010 Lin J, Lee IM, Song Y, Cook NR, Selhub J, Manson JE, Buring JE, Zhang SM. Plasma homocysteine and cysteine and risk of breast cancer in women. Cancer Research. 70: 2397-405. PMID 20197471 DOI: 10.1158/0008-5472.Can-09-3648  0.31
2010 Schnabel RB, Larson MG, Yamamoto JF, Sullivan LM, Pencina MJ, Meigs JB, Tofler GH, Selhub J, Jacques PF, Wolf PA, Magnani JW, Ellinor PT, Wang TJ, Levy D, Vasan RS, et al. Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation. 121: 200-7. PMID 20048208 DOI: 10.1161/Circulationaha.109.882241  0.334
2010 Hazra A, Selhub J, Chao WH, Ueland PM, Hunter DJ, Baron JA. Uracil misincorporation into DNA and folic acid supplementation. The American Journal of Clinical Nutrition. 91: 160-5. PMID 19923375 DOI: 10.3945/Ajcn.2009.28527  0.417
2010 Morris MS, Sakakeeny L, Jacques PF, Picciano MF, Selhub J. Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status. The Journal of Nutrition. 140: 103-10. PMID 19906811 DOI: 10.3945/Jn.109.114397  0.75
2010 Wei EK, Lee JE, Giovannucci E, Fuchs C, Selhub J, Hankinson SE, Stampfer M, Willett W, Ma J. Abstract B102: Plasma vitamin B6 and the risk of colorectal cancer in three large prospective cohorts Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B102  0.448
2009 Wu K, Platz EA, Willett WC, Fuchs CS, Selhub J, Rosner BA, Hunter DJ, Giovannucci E. A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma. The American Journal of Clinical Nutrition. 90: 1623-31. PMID 19864409 DOI: 10.3945/Ajcn.2009.28319  0.374
2009 Weinstein SJ, Mackrain K, Stolzenberg-Solomon RZ, Selhub J, Virtamo J, Albanes D. Serum creatinine and prostate cancer risk in a prospective study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 2643-9. PMID 19755655 DOI: 10.1158/1055-9965.Epi-09-0322  0.311
2009 Hazra A, Kraft P, Lazarus R, Chen C, Chanock SJ, Jacques P, Selhub J, Hunter DJ. Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Human Molecular Genetics. 18: 4677-87. PMID 19744961 DOI: 10.1093/Hmg/Ddp428  0.401
2009 Page JH, Ma J, Chiuve SE, Stampfer MJ, Selhub J, Manson JE, Rimm EB. Plasma vitamin B(6) and risk of myocardial infarction in women. Circulation. 120: 649-55. PMID 19667235 DOI: 10.1161/Circulationaha.108.809038  0.399
2009 Le Marchand L, White KK, Nomura AM, Wilkens LR, Selhub JS, Tiirikainen M, Goodman MT, Murphy SP, Henderson BE, Kolonel LN. Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 2195-201. PMID 19661077 DOI: 10.1158/1055-9965.EPI-09-0141  0.388
2009 Paul L, Cattaneo M, D'Angelo A, Sampietro F, Fermo I, Razzari C, Fontana G, Eugene N, Jacques PF, Selhub J. Telomere length in peripheral blood mononuclear cells is associated with folate status in men. The Journal of Nutrition. 139: 1273-8. PMID 19458030 DOI: 10.3945/Jn.109.104984  0.338
2009 Lee JE, Li H, Giovannucci E, Lee IM, Selhub J, Stampfer M, Ma J. Prospective study of plasma vitamin B6 and risk of colorectal cancer in men. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1197-202. PMID 19336555 DOI: 10.1158/1055-9965.Epi-08-1001  0.442
2009 Achón M, Alonso-Aperte E, Varela-Moreiras G, Selhub J. Mild methionine excess does not affect thymidylate synthesis or inflammation markers expression in human aortic endothelial cells. Annals of Nutrition & Metabolism. 54: 28-34. PMID 19246892 DOI: 10.1159/000205317  0.389
2009 Selhub J, Morris MS, Jacques PF, Rosenberg IH. Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency. The American Journal of Clinical Nutrition. 89: 702S-6S. PMID 19141696 DOI: 10.3945/Ajcn.2008.26947C  0.479
2009 Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu CR, Liu CH, Hwang J, Wilcox AG, Selzer RH. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke; a Journal of Cerebral Circulation. 40: 730-6. PMID 19118243 DOI: 10.1161/Strokeaha.108.526798  0.317
2009 Hamer DH, Sempértegui F, Estrella B, Tucker KL, Rodríguez A, Egas J, Dallal GE, Selhub J, Griffiths JK, Meydani SN. Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians. The Journal of Nutrition. 139: 113-9. PMID 19056665 DOI: 10.3945/Jn.108.095091  0.4
2008 Wilson PW, Pencina M, Jacques P, Selhub J, D'Agostino R, O'Donnell CJ. C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circulation. Cardiovascular Quality and Outcomes. 1: 92-7. PMID 20031795 DOI: 10.1161/Circoutcomes.108.831198  0.302
2008 Troen AM, Chao WH, Crivello NA, D'Anci KE, Shukitt-Hale B, Smith DE, Selhub J, Rosenberg IH. Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine. The Journal of Nutrition. 138: 2502-9. PMID 19022979 DOI: 10.3945/Jn.108.093641  0.338
2008 Kalmbach RD, Choumenkovitch SF, Troen AP, Jacques PF, D'Agostino R, Selhub J. A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. The Journal of Nutrition. 138: 2323-7. PMID 19022952 DOI: 10.3945/Jn.108.096404  0.381
2008 Weinstein SJ, Albanes D, Selhub J, Graubard B, Lim U, Taylor PR, Virtamo J, Stolzenberg-Solomon R. One-carbon metabolism biomarkers and risk of colon and rectal cancers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3233-40. PMID 18990766 DOI: 10.1158/1055-9965.Epi-08-0459  0.313
2008 Hazra A, Kraft P, Selhub J, Giovannucci EL, Thomas G, Hoover RN, Chanock SJ, Hunter DJ. Common variants of FUT2 are associated with plasma vitamin B12 levels. Nature Genetics. 40: 1160-2. PMID 18776911 DOI: 10.1038/Ng.210  0.445
2008 Selhub J. Public health significance of elevated homocysteine. Food and Nutrition Bulletin. 29: S116-25. PMID 18709886 DOI: 10.1177/15648265080292S116  0.503
2008 Selhub J, Jacques PF, Dallal G, Choumenkovitch S, Rogers G. The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status. Food and Nutrition Bulletin. 29: S67-73. PMID 18709882 DOI: 10.1177/15648265080292S110  0.477
2008 Wolpin BM, Wei EK, Ng K, Meyerhardt JA, Chan JA, Selhub J, Giovannucci EL, Fuchs CS. Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3222-8. PMID 18591557 DOI: 10.1200/Jco.2008.16.1943  0.387
2008 Morris MS, Picciano MF, Jacques PF, Selhub J. Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004. The American Journal of Clinical Nutrition. 87: 1446-54. PMID 18469270 DOI: 10.1093/Ajcn/87.5.1446  0.325
2008 McLean RR, Jacques PF, Selhub J, Fredman L, Tucker KL, Samelson EJ, Kiel DP, Cupples LA, Hannan MT. Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women. The Journal of Clinical Endocrinology and Metabolism. 93: 2206-12. PMID 18364381 DOI: 10.1210/Jc.2007-2710  0.381
2008 Lin J, Lee IM, Cook NR, Selhub J, Manson JE, Buring JE, Zhang SM. Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women. The American Journal of Clinical Nutrition. 87: 734-43. PMID 18326613 DOI: 10.1093/Ajcn/87.3.734  0.437
2008 Gibson T, Weinstein S, Mayne S, Selhub J, Taylor P, Pfeiffer R, Virtamo J, Albanes D, Stolzenberg-Solomon R. Abstract B124: A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma. Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B124  0.419
2008 Selhub J, Morris MS, Jacques PF. Reply to Quinlivan: Postfortification, folate intake in vitamin B12 deficiency is positively related to homocysteine and methylmalonic acid Proceedings of the National Academy of Sciences of the United States of America. 105. DOI: 10.1073/Pnas.0800158105  0.455
2007 Troen AM, French EE, Roberts JF, Selhub J, Ordovas JM, Parnell LD, Lai CQ. Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age (Dordrecht, Netherlands). 29: 29-39. PMID 19424828 DOI: 10.1007/S11357-006-9018-4  0.321
2007 Selhub J, Morris MS, Jacques PF. In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proceedings of the National Academy of Sciences of the United States of America. 104: 19995-20000. PMID 18056804 DOI: 10.1073/Pnas.0709487104  0.483
2007 Arabelovic S, Sam G, Dallal GE, Jacques PF, Selhub J, Rosenberg IH, Roubenoff R. Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis. Journal of the American College of Nutrition. 26: 453-5. PMID 17914133 DOI: 10.1080/07315724.2007.10719635  0.328
2007 Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS. Multiple biomarkers and the risk of incident hypertension. Hypertension. 49: 432-8. PMID 17242302 DOI: 10.1161/01.Hyp.0000256956.61872.Aa  0.312
2007 Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. The American Journal of Clinical Nutrition. 85: 193-200. PMID 17209196 DOI: 10.1093/Ajcn/85.1.193  0.413
2006 Póo-Prieto R, Haytowitz DB, Holden JM, Rogers G, Choumenkovitch SF, Jacques PF, Selhub J. Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products. The Journal of Nutrition. 136: 3079-83. PMID 17116723 DOI: 10.1093/Jn/136.12.3079  0.321
2006 Troen AM, Shukitt-Hale B, Chao WH, Albuquerque B, Smith DE, Selhub J, Rosenberg J. The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. Journal of Alzheimer's Disease : Jad. 9: 381-92. PMID 16917146 DOI: 10.3233/Jad-2006-9403  0.357
2006 Lievers KJ, Kluijtmans LA, Blom HJ, Wilson PW, Selhub J, Ordovas JM. Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study. European Journal of Human Genetics : Ejhg. 14: 1125-9. PMID 16791140 DOI: 10.1038/Sj.Ejhg.5201677  0.384
2006 Selhub J. The many facets of hyperhomocysteinemia: studies from the Framingham cohorts. The Journal of Nutrition. 136: 1726S-1730S. PMID 16702347 DOI: 10.1093/Jn/136.6.1726S  0.483
2006 Cho E, Zeisel SH, Jacques P, Selhub J, Dougherty L, Colditz GA, Willett WC. Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. The American Journal of Clinical Nutrition. 83: 905-11. PMID 16600945 DOI: 10.1093/Ajcn/83.4.905  0.419
2006 Menon V, Sarnak MJ, Greene T, Wang X, Pereira AA, Beck GJ, Kusek JW, Selhub J, Collins AJ, Levey AS, Shlipak MG. Relationship between homocysteine and mortality in chronic kidney disease. Circulation. 113: 1572-7. PMID 16549639 DOI: 10.1161/Circulationaha.105.570127  0.343
2006 Troen AM, Mitchell B, Sorensen B, Wener MH, Johnston A, Wood B, Selhub J, McTiernan A, Yasui Y, Oral E, Potter JD, Ulrich CM. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. The Journal of Nutrition. 136: 189-94. PMID 16365081 DOI: 10.1093/Jn/136.1.189  0.419
2006 Rosenberg IH, Selhub J. Folate and vitamin B12 transport systems in the developing infant Journal of Pediatrics. 149. DOI: 10.1016/J.Jpeds.2006.06.053  0.397
2005 Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environmental Toxicology and Pharmacology. 19: 1-7. PMID 21783456 DOI: 10.1016/J.Etap.2004.01.007  0.303
2005 Chiang EP, Selhub J, Bagley PJ, Dallal G, Roubenoff R. Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis Research & Therapy. 7: R1404-11. PMID 16277693 DOI: 10.1186/Ar1839  0.45
2005 Chiang EP, Smith DE, Selhub J, Dallal G, Wang YC, Roubenoff R. Inflammation causes tissue-specific depletion of vitamin B6. Arthritis Research & Therapy. 7: R1254-62. PMID 16277678 DOI: 10.1186/ar1821  0.382
2005 Friedman AN, Hunsicker LG, Selhub J, Bostom AG. Total plasma homocysteine and arteriosclerotic outcomes in type 2 diabetes with nephropathy Journal of the American Society of Nephrology. 16: 3397-3402. PMID 16162814 DOI: 10.1681/Asn.2004100846  0.307
2005 Elias MF, Sullivan LM, D'Agostino RB, Elias PK, Jacques PF, Selhub J, Seshadri S, Au R, Beiser A, Wolf PA. Homocysteine and cognitive performance in the Framingham offspring study: age is important. American Journal of Epidemiology. 162: 644-53. PMID 16107567 DOI: 10.1093/Aje/Kwi259  0.363
2005 Lim U, Peng K, Shane B, Stover PJ, Litonjua AA, Weiss ST, Gaziano JM, Strawderman RL, Raiszadeh F, Selhub J, Tucker KL, Cassano PA. Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. The Journal of Nutrition. 135: 1989-94. PMID 16046727 DOI: 10.1093/Jn/135.8.1989  0.311
2005 Friedman AN, Hunsicker LG, Selhub J, Bostom AG. C-reactive protein as a predictor of total arteriosclerotic outcomes in type 2 diabetic nephropathy Kidney International. 68: 773-778. PMID 16014055 DOI: 10.1111/J.1523-1755.2005.00456.X  0.316
2005 Morris MS, Jacques PF, Selhub J. Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone. 37: 234-42. PMID 15950558 DOI: 10.1016/J.Bone.2005.04.017  0.446
2005 Ramaekers VT, Rothenberg SP, Sequeira JM, Opladen T, Blau N, Quadros EV, Selhub J. Autoantibodies to folate receptors in the cerebral folate deficiency syndrome. The New England Journal of Medicine. 352: 1985-91. PMID 15888699 DOI: 10.1056/Nejmoa043160  0.343
2005 Wei EK, Giovannucci E, Selhub J, Fuchs CS, Hankinson SE, Ma J. Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women Journal of the National Cancer Institute. 97: 684-692. PMID 15870439 DOI: 10.1093/Jnci/Dji116  0.414
2005 Davis SR, Quinlivan EP, Shelnutt KP, Maneval DR, Ghandour H, Capdevila A, Coats BS, Wagner C, Selhub J, Bailey LB, Shuster JJ, Stacpoole PW, Gregory JF. The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women. The Journal of Nutrition. 135: 1040-4. PMID 15867278 DOI: 10.1093/Jn/135.5.1040  0.356
2005 Menon V, Wang X, Greene TOM, Beck GJ, Kusek JW, Selhub J, Levey AS, Sarnak MJ. Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins Kidney International. 67: 1539-1546. PMID 15780109 DOI: 10.1111/J.1523-1755.2005.00234.X  0.469
2005 Kado DM, Karlamangla AS, Huang MH, Troen A, Rowe JW, Selhub J, Seeman TE. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. The American Journal of Medicine. 118: 161-7. PMID 15694902 DOI: 10.1016/J.Amjmed.2004.08.019  0.4
2005 Tucker KL, Hannan MT, Qiao N, Jacques PF, Selhub J, Cupples LA, Kiel DP. Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 152-8. PMID 15619681 DOI: 10.1359/Jbmr.041018  0.457
2004 Shai I, Stampfer MJ, Ma J, Manson JE, Hankinson SE, Cannuscio C, Selhub J, Curhan G, Rimm EB. Homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors. Atherosclerosis. 177: 375-381. PMID 15530913 DOI: 10.1016/J.Atherosclerosis.2004.07.020  0.368
2004 Ghandour H, Chen Z, Selhub J, Rozen R. Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates Journal of Nutrition. 134: 2975-2978. PMID 15514261 DOI: 10.1093/Jn/134.11.2975  0.349
2004 Chen J, Kyte C, Valcin M, Chan W, Wetmur JG, Selhub J, Hunter DJ, Ma J. Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. International Journal of Cancer. Journal International Du Cancer. 110: 617-20. PMID 15122597 DOI: 10.1002/Ijc.20148  0.342
2004 Tucker KL, Olson B, Bakun P, Dallal GE, Selhub J, Rosenberg IH. Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial. The American Journal of Clinical Nutrition. 79: 805-11. PMID 15113718 DOI: 10.1093/Ajcn/79.5.805  0.343
2004 Choi SW, Friso S, Ghandour H, Bagley PJ, Selhub J, Mason JB. Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium. The Journal of Nutrition. 134: 750-5. PMID 15051821 DOI: 10.1093/Jn/134.4.750  0.408
2004 Hossain T, Rosenberg I, Selhub J, Kishore G, Beachy R, Schubert K. Enhancement of folates in plants through metabolic engineering. Proceedings of the National Academy of Sciences of the United States of America. 101: 5158-63. PMID 15044686 DOI: 10.1073/Pnas.0401342101  0.332
2004 McLean RR, Karasik D, Selhub J, Tucker KL, Ordovas JM, Russo GT, Cupples LA, Jacques PF, Kiel DP. Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 410-8. PMID 15040829 DOI: 10.1359/Jbmr.0301261  0.307
2004 Friedman AN, Hunsicker LG, Selhub J, Bostom AG. Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy Atherosclerosis. 172: 121-125. PMID 14709365 DOI: 10.1016/J.Atherosclerosis.2003.09.011  0.386
2003 Troen AM, Lutgens E, Smith DE, Rosenberg IH, Selhub J. The atherogenic effect of excess methionine intake. Proceedings of the National Academy of Sciences of the United States of America. 100: 15089-94. PMID 14657334 DOI: 10.1073/Pnas.2436385100  0.344
2003 Russo GT, Friso S, Jacques PF, Rogers G, Cucinotta D, Wilson PW, Ordovas JM, Rosenberg IH, Selhub J. Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort. The Journal of Nutrition. 133: 3416-21. PMID 14608052 DOI: 10.1093/Jn/133.11.3416  0.344
2003 Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology Letters. 145: 167-74. PMID 14581169 DOI: 10.1016/S0378-4274(03)00307-2  0.334
2003 Must A, Jacques PF, Rogers G, Rosenberg IH, Selhub J. Serum total homocysteine concentrations in children and adolescents: results from the third National Health and Nutrition Examination Survey (NHANES III). The Journal of Nutrition. 133: 2643-9. PMID 12888652 DOI: 10.1093/Jn/133.8.2643  0.314
2003 Kim MK, Ordovas JM, Selhub J, Campos H. B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica Journal of the American College of Nutrition. 22: 224-231. PMID 12805249 DOI: 10.1080/07315724.2003.10719297  0.435
2003 Anguera MC, Suh JR, Ghandour H, Nasrallah IM, Selhub J, Stover PJ. Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation. The Journal of Biological Chemistry. 278: 29856-62. PMID 12764149 DOI: 10.1074/Jbc.M302883200  0.34
2003 Miller JW, Selhub J, Nadeau MR, Thomas CA, Feldman RG, Wolf PA. Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. Neurology. 60: 1125-9. PMID 12682318 DOI: 10.1212/01.Wnl.0000055899.24594.8E  0.419
2003 Chiang EPI, Bagley PJ, Selhub J, Nadeau M, Roubenoff R. Abnormal vitamin B6 status is associated with severity of symptoms in patients with rheumatoid arthritis American Journal of Medicine. 114: 283-287. PMID 12681455 DOI: 10.1016/S0002-9343(02)01528-0  0.359
2003 Chiang EPI, Bagley PJ, Roubenoff R, Nadeau M, Selhub J. Plasma pyridoxal 5′-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status1-3 Journal of Nutrition. 133: 1056-1059. PMID 12672918 DOI: 10.1093/Jn/133.4.1056  0.448
2003 Zhang SM, Willett WC, Selhub J, Hunter DJ, Giovannucci EL, Holmes MD, Colditz GA, Hankinson SE. Plasma Folate, Vitamin B6, Vitamin B12, Homocysteine, and Risk of Breast Cancer Journal of the National Cancer Institute. 95: 373-380. PMID 12618502 DOI: 10.1093/Jnci/95.5.373  0.419
2003 Morris MS, Fava M, Jacques PF, Selhub J, Rosenberg IH. Depression and folate status in the US population Psychotherapy and Psychosomatics. 72: 80-87. PMID 12601225 DOI: 10.1159/000068692  0.315
2003 Friedman AN, Bostom AG, Laliberty P, Selhub J, Shemin D. The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: A randomized, controlled study American Journal of Kidney Diseases. 41: 442-446. PMID 12552508 DOI: 10.1053/Ajkd.2003.50054  0.405
2003 Jacques PF, Bostom AG, Selhub J, Rich S, Ellison RC, Eckfeldt JH, Gravel RA, Rozen R. Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study. Atherosclerosis. 166: 49-55. PMID 12482550 DOI: 10.1016/S0021-9150(02)00204-6  0.372
2003 Zhang SM, Willett WC, Selhub J, Hunter DJ, Giovannucci EL, Holmes MD, Colditz GA, Hankinson SE. RESPONSE: Re: Plasma Folate, Vitamin B6, Vitamin B12, Homocysteine, and Risk of Breast Cancer Journal of the National Cancer Institute. 95: 1091-1091. DOI: 10.1093/Jnci/95.14.1091-A  0.433
2002 Kado DM, Bucur A, Selhub J, Rowe JW, Seeman T. Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging. The American Journal of Medicine. 113: 537-42. PMID 12459398 DOI: 10.1016/S0002-9343(02)01269-X  0.329
2002 Ronnenberg AG, Goldman MB, Chen D, W Aitken I, C Willett W, Selhub J, Xu X. Preconception homocysteine and B vitamin status and birth outcomes in Chinese women American Journal of Clinical Nutrition. 76: 1385-1391. PMID 12450907 DOI: 10.1093/Ajcn/76.6.1385  0.397
2002 Tofler GH, D'Agostino RB, Jacques PF, Bostom AG, Wilson PWF, Lipinska I, Mittleman MA, Selhub J. Association between increased homocysteine levels and impaired fibrinolytic potential: Potential mechanism for cardiovascular risk Thrombosis and Haemostasis. 88: 799-804. PMID 12428097 DOI: 10.1055/S-0037-1613305  0.34
2002 Ghandour H, Bagley PJ, Shemin D, Hsu N, Jacques PF, Dworkin L, Bostom AG, Selhub J. Distribution of plasma folate forms in hemodialysis patients receiving high daily doses of L-folinic or folic acid. Kidney International. 62: 2246-9. PMID 12427152 DOI: 10.1046/J.1523-1755.2002.00666.X  0.341
2002 Sarnak MJ, Wang SR, Beck GJ, Kusek JW, Selhub J, Greene T, Levey AS. Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression American Journal of Kidney Diseases. 40: 932-939. PMID 12407637 DOI: 10.1053/ajkd.2002.36323  0.326
2002 Friedman AN, Hunsicker LG, Selhub J, Bostom AG. Proteinuria as a predictor of total plasma homocysteine levels in type 2 diabetic nephropathy Diabetes Care. 25: 2037-2041. PMID 12401753 DOI: 10.2337/Diacare.25.11.2037  0.374
2002 Morris MS, Jacques PF, Rosenberg IH, Selhub J. Elevated serum methylmalonic acid concentrations are common among elderly Americans Journal of Nutrition. 132: 2799-2803. PMID 12221248 DOI: 10.1093/Jn/132.9.2799  0.39
2002 Choumenkovitch SF, Selhub J, Wilson PWF, Rader JI, Rosenberg IH, Jacques PF. Folic acid intake from fortification in United States exceeds predictions Journal of Nutrition. 132: 2792-2798. PMID 12221247 DOI: 10.1093/Jn/132.9.2792  0.362
2002 Tran P, Hiou-Tim F, Frosst P, Lussier-Cacan S, Bagley P, Selhub J, Bottiglieri T, Rozen R. The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr. Molecular Genetics and Metabolism. 76: 297-304. PMID 12208134 DOI: 10.1016/S1096-7192(02)00108-7  0.313
2002 Choumenkovitch SF, Selhub J, Bagley PJ, Maeda N, Nadeau MR, Smith DE, Choi SW. In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific. The Journal of Nutrition. 132: 2157-60. PMID 12163655 DOI: 10.1093/Jn/132.8.2157  0.314
2002 Friedman AN, Rosenberg IH, Selhub J, Levey AS, Bostom AG. Hyperhomocysteinemia in renal transplant recipients American Journal of Transplantation. 2: 308-313. PMID 12118851 DOI: 10.1034/J.1600-6143.2002.20404.X  0.334
2002 Ronnenberg AG, Goldman MB, Chen D, Aitken IW, Willett WC, Selhub J, Xu X. Preconception folate and vitamin B(6) status and clinical spontaneous abortion in Chinese women. Obstetrics and Gynecology. 100: 107-13. PMID 12100811 DOI: 10.1016/S0029-7844(02)01978-6  0.403
2002 Chen J, Ma J, Stampfer MJ, Palomeque C, Selhub J, Hunter DJ. Linkage disequilibrium between the 677C>t and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer Pharmacogenetics. 12: 339-342. PMID 12042673 DOI: 10.1097/00008571-200206000-00011  0.306
2002 Ghandour H, Lin BF, Choi SW, Mason JB, Selhub J. Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins. The Journal of Nutrition. 132: 1357-60. PMID 12042458 DOI: 10.1093/Jn/132.6.1357  0.309
2002 Vargas-Martinez C, Ordovas JM, Wilson PW, Selhub J. The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort Journal of Nutrition. 132: 1176-1179. PMID 12042430 DOI: 10.1093/Jn/132.6.1176  0.386
2002 Burgoon JM, Selhub J, Nadeau M, Sadler TW. Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model. Teratology. 65: 219-27. PMID 11967921 DOI: 10.1002/Tera.10040  0.357
2002 Bostom AG, Jacques PF, Liaugaudas G, Rogers G, Rosenberg IH, Selhub J. Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 488-491. PMID 11884295 DOI: 10.1161/Hq0302.105369  0.301
2002 Bostom AG, Kronenberg F, Jacques PF, Kuen E, Ritz E, König P, Kraatz G, Lhotta K, Mann JF, Müller GA, Neyer U, Riegel W, Schwenger V, Riegler P, Selhub J. Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate. Atherosclerosis. 159: 219-23. PMID 11689224 DOI: 10.1016/S0021-9150(01)00502-0  0.383
2001 Choumenkovitch SF, Jacques PF, Nadeau MR, Wilson PWF, Rosenberg IH, Selhub J. Folic acid fortification increases red blood cell folate concentrations in the Framingham study Journal of Nutrition. 131: 3277-3280. PMID 11739880 DOI: 10.1093/Jn/131.12.3277  0.408
2001 Goodman JE, Lavigne JA, Wu K, Helzlsouer KJ, Strickland PT, Selhub J, Yager JD. COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk. Carcinogenesis. 22: 1661-5. PMID 11577006 DOI: 10.1093/Carcin/22.10.1661  0.346
2001 Shemin D, Bostom AG, Selhub J. Treatment of hyperhomocysteinemia in end-stage renal disease American Journal of Kidney Diseases. 38: S91-S94. PMID 11576930 DOI: 10.1053/Ajkd.2001.27412  0.322
2001 Meigs JB, Jacques PF, Selhub J, Singer DE, Nathan DM, Rifai N, D'Agostino RB, Wilson PWF. Fasting plasma homocysteine levels in the insulin resistance syndrome: The framingham offspring study Diabetes Care. 24: 1403-1410. PMID 11473077 DOI: 10.2337/Diacare.24.8.1403  0.349
2001 Weinstein SJ, Ziegler RG, Selhub J, Fears TR, Strickler HD, Brinton LA, Hamman RF, Levine RS, Mallin K, Stolley PD. Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US women. Cancer Causes & Control : Ccc. 12: 317-24. PMID 11456227 DOI: 10.1023/A:1011290103779  0.326
2001 Friso S, Jacques PF, Wilson PWF, Rosenberg IH, Selhub J. Low circulating vitamin B6 is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels Circulation. 103: 2788-2791. PMID 11401933 DOI: 10.1161/01.Cir.103.23.2788  0.498
2001 Bostom AG, Kronenberg F, Gohh RY, Schwenger V, Kuen E, König P, Kraatz G, Lhotta K, Mann JFE, Müller GA, Neyer U, Riegel W, Riegler P, Ritz E, Selhub J. Chronic renal transplantation: a model for the hyperhomocysteinemia of renal insufficiency. Atherosclerosis. 156: 227-230. PMID 11369018 DOI: 10.1016/S0021-9150(00)00613-4  0.346
2001 Morris MS, Jacques PF, Rosenberg IH, Selhub J. Hyperhomocysteinemia associated with poor recall in the third national health and nutrition examination survey American Journal of Clinical Nutrition. 73: 927-933. PMID 11333847 DOI: 10.1093/Ajcn/73.5.927  0.364
2001 Hartman TJ, Woodson K, Stolzenberg-Solomon R, Virtamo J, Selhub J, Barrett MJ, Albanes D. Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men. American Journal of Epidemiology. 153: 688-94. PMID 11282797 DOI: 10.1093/Aje/153.7.688  0.416
2001 Chen J, Stampfer MJ, Ma J, Selhub J, Malinow MR, Hennekens CH, Hunter DJ. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction Atherosclerosis. 154: 667-672. PMID 11257268 DOI: 10.1016/S0021-9150(00)00469-X  0.366
2001 Morris MS, Bostom AG, Jacques PF, Selhub J, Rosenberg IH. Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey Atherosclerosis. 155: 195-200. PMID 11223442 DOI: 10.1016/S0021-9150(00)00537-2  0.361
2001 Bostom AG, Shemin D, Gohh RY, Beaulieu AJ, Bagley P, Massy ZA, Jacques PF, Dworkin L, Selhub J. Treatment of hyperhomocysteinemia in hemodialysis patients and renal transplant recipients Kidney International, Supplement. 59: S246-S252. PMID 11169020 DOI: 10.1046/J.1523-1755.2001.59780246.X  0.383
2001 Yango A, Shemin D, Hsu N, Jacques PF, Dworkin L, Selhub J, Bostom AG. Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients. Kidney International. 59: 324-7. PMID 11135086 DOI: 10.1046/J.1523-1755.2001.00507.X  0.347
2001 Morris MS, Jacques PF, Rosenberg IH, Selhub J, Bowman BA, Gunter EW, Wright JD, Johnson CL. Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III. The Journal of Nutrition. 130: 3073-6. PMID 11110872 DOI: 10.1093/Jn/130.12.3073  0.382
2000 Selhub J, Jacques PF, Bostom AG, Wilson PWF, Rosenberg IH. Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification Public Health Reviews. 28: 117-145. PMID 11411265  0.432
2000 Pfeiffer CM, Caudill SP, Gunter EW, Bowman BA, Jacques PF, Selhub J, Johnson CL, Miller DT, Sampson EJ. Analysis of factors influencing the comparison of homocysteine values between the Third National Health and Nutrition Examination Survey (NHANES) and NHANES 1999+. The Journal of Nutrition. 130: 2850-4. PMID 11053531 DOI: 10.1093/Jn/130.11.2850  0.344
2000 McMichael MA, Freeman LM, Selhub J, Rozanski EA, Brown DJ, Nadeau MR, Rush JE. Plasma homocysteine, B vitamins, and amino acid concentrations in cats with cardiomyopathy and arterial thromboembolism. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 14: 507-12. PMID 11012114 DOI: 10.1111/J.1939-1676.2000.Tb02268.X  0.461
2000 Appel LJ, Miller ER, Jee SH, Stolzenberg-Solomon R, Lin PH, Erlinger T, Nadeau MR, Selhub J. Effect of dietary patterns on serum homocysteine: results of a randomized, controlled feeding study. Circulation. 102: 852-7. PMID 10952952 DOI: 10.1161/01.Cir.102.8.852  0.42
2000 Alberg AJ, Selhub J, Shah KV, Viscidi RP, Comstock GW, Helzlsouer KJ. The risk of cervical cancer in relation to serum concentrations of folate, vitamin B12, and homocysteine. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 9: 761-4. PMID 10919749  0.31
2000 Goodman MT, McDuffie K, Hernandez B, Wilkens LR, Selhub J. Case-control study of plasma folate, homocysteine, vitamin B12, and cysteine as markers of cervical dysplasia Cancer. 89: 376-382. PMID 10918169 DOI: 10.1002/1097-0142(20000715)89:2<376::Aid-Cncr24>3.0.Co;2-O  0.44
2000 Morris MS, Jacques PF, Selhub J, Rosenberg IH. Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey American Journal of Epidemiology. 152: 140-148. PMID 10909951 DOI: 10.1093/Aje/152.2.140  0.364
2000 Mudd SH, Finkelstein JD, Refsum H, Ueland PM, Malinow MR, Lentz SR, Jacobsen DW, Brattström L, Wilcken B, Wilcken DE, Blom HJ, Stabler SP, Allen RH, Selhub J, Rosenberg IH. Homocysteine and its disulfide derivatives: a suggested consensus terminology. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1704-6. PMID 10894806 DOI: 10.1161/01.Atv.20.7.1704  0.313
2000 Bostom AG, Shemin D, Bagley P, Massy ZA, Zanabli A, Christopher K, Spiegel P, Jacques PF, Dworkin L, Selhub J. Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients Circulation. 101: 2829-2832. PMID 10859289 DOI: 10.1161/01.Cir.101.24.2829  0.352
2000 Selhub J, Bagley LC, Miller J, Rosenberg IH. B vitamins, homocysteine, and neurocognitive function in the elderly American Journal of Clinical Nutrition. 71. PMID 10681269 DOI: 10.1093/Ajcn/71.2.614S  0.321
2000 Tucker KL, Rich S, Rosenberg I, Jacques P, Dallal G, Wilson PW, Selhub J. Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring study. The American Journal of Clinical Nutrition. 71: 514-22. PMID 10648266 DOI: 10.1093/Ajcn/71.2.514  0.48
2000 Stickel F, Choi S, Kim Y, Bagley PJ, Seitz HK, Russell RM, Selhub J, Mason JB. Effect of chronic alcohol consumption on total plasma homocysteine level in rats. Alcoholism: Clinical and Experimental Research. 24: 259-264. DOI: 10.1111/J.1530-0277.2000.Tb04606.X  0.404
1999 Beaulieu AJ, Gohh RY, Han H, Hakas D, Jacques PF, Selhub J, Bostom AG. Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2918-2921. PMID 10591669 DOI: 10.1161/01.Atv.19.12.2918  0.348
1999 Selhub J, Jacques PF, Rosenberg IH, Rogers G, Bowman BA, Gunter EW, Wright JD, Johnson CL. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations. Annals of Internal Medicine. 131: 331-9. PMID 10475885 DOI: 10.7326/0003-4819-131-5-199909070-00003  0.448
1999 Bostom AG, Silbershatz H, Rosenberg IH, Selhub J, D'Agostino RB, Wolf PA, Jacques PF, Wilson PWF. Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women Archives of Internal Medicine. 159: 1077-1080. PMID 10335684 DOI: 10.1001/Archinte.159.10.1077  0.358
1999 Jacques PF, Selhub J, Bostom AG, Wilson PWF, Rosenberg IH. The effect of folic acid fortification on plasma folate and total homocysteine concentrations New England Journal of Medicine. 340: 1449-1454. PMID 10320382 DOI: 10.1056/Nejm199905133401901  0.425
1999 Stolzenberg-Solomon RZ, Miller ER, Maguire MG, Selhub J, Appel LJ. Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population American Journal of Clinical Nutrition. 69: 467-475. PMID 10075332 DOI: 10.1093/Ajcn/69.3.467  0.474
1999 Mason JB, Selhub J. Disease Prevention: Broadening the Definition of Folate Nutrition Nutrition in Clinical Care. 2: 82-86. DOI: 10.1046/J.1523-5408.1999.00088.X  0.404
1998 Seyoum E, Selhub J. Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action Journal of Nutrition. 128: 1956-1960. PMID 9808649 DOI: 10.1093/Jn/128.11.1956  0.314
1998 Selhub J, D'Angelo A. Relationship between homocysteine and thrombotic disease American Journal of the Medical Sciences. 316: 129-141. PMID 9704666 DOI: 10.1016/S0002-9629(15)40387-8  0.415
1997 Selhub J, D'Angelo A. Hyperhomocysteinemia and thrombosis: Acquired conditions Thrombosis and Haemostasis. 78: 527-531. PMID 9198209 DOI: 10.1055/S-0038-1657582  0.42
1997 Christensen B, Frosst P, Lussier-Cacan S, Selhub J, Goyette P, Rosenblatt DS, Genest J, Rozen R. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 569-73. PMID 9102178 DOI: 10.1161/01.Atv.17.3.569  0.344
1997 Brantigan CO, Tucker KL, Jacques P, Selhub J. Folate supplementation and the risk of masking vitamin B12 deficiency [5] Journal of the American Medical Association. 277: 884-885. PMID 9062324  0.327
1997 Miller JW, Shukitt-Hale B, Villalobos-Molina R, Nadeau MR, Selhub J, Joseph JA. Effect of L-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats. Clinical Neuropharmacology. 20: 55-66. PMID 9037574 DOI: 10.1097/00002826-199702000-00007  0.334
1997 Robinson K, Gupta A, Dennis V, Arheart K, Chaudhary D, Green R, Vigo P, Mayer EL, Selhub J, Kutner M, Jacobsen DW. Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations. Circulation. 94: 2743-8. PMID 8941098 DOI: 10.1161/01.Cir.94.11.2743  0.325
1997 Daly D, Miller JW, Nadeau MR, Selhub J. The effect of L-dopa administration and folate deficiency on plasma homocysteine concentrations in rats Journal of Nutritional Biochemistry. 8: 634-640. DOI: 10.1016/S0955-2863(97)00110-1  0.327
1996 Tucker KL, Selhub J, Wilson PWF, Rosenberg IH. Dietary intake pattern relates to plasma folate and homocysteine concentrations in the Framingham Heart Study Journal of Nutrition. 126: 3025-3031. PMID 9001370 DOI: 10.1093/Jn/126.12.3025  0.426
1996 Tucker KL, Mahnken B, Wilson PWF, Jacques P, Selhub J. Folic acid fortification of the food supply: Potential benefits and risks for the elderly population Journal of the American Medical Association. 276: 1879-1885. PMID 8968013 DOI: 10.1001/Jama.1996.03540230029031  0.478
1996 Petri M, Roubenoff R, Dallal GE, Nadeau MR, Selhub J, Rosenberg IH. Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus Lancet. 348: 1120-1124. PMID 8888164 DOI: 10.1016/S0140-6736(96)03032-2  0.359
1996 Selhub J, Jacques PF, Bostom AG, D'Agostino RB, Wilson PW, Belanger AJ, O'Leary DH, Wolf PA, Rush D, Schaefer EJ, Rosenberg IH. Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population. The Journal of Nutrition. 126: 1258S-65S. PMID 8642467 DOI: 10.1093/jn/126.suppl_4.1258s  0.502
1996 Rosenberg IH, Bostom A, Jacques P, Selhub J. Gene-diet interactions in plasma homocysteine regulation Current Opinion in Endocrinology and Diabetes. 3: 497-500. DOI: 10.1097/00060793-199612000-00009  0.311
1995 Gospe SM, Gietzen DW, Summers PJ, Lunetta JM, Miller JW, Selhub J, Ellis WG, Clifford AJ. Behavioral and neurochemical changes in folate-deficient mice. Physiology & Behavior. 58: 935-41. PMID 8577891 DOI: 10.1016/0031-9384(95)00156-D  0.303
1995 Roubenoff R, Roubenoff RA, Selhub J, Nadeau MR, Cannon JG, Freeman LM, Dinarello CA, Rosenberg IH. Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation. Arthritis and Rheumatism. 38: 105-9. PMID 7818558 DOI: 10.1002/Art.1780380116  0.406
1995 Dalery K, Lussier-Cacan S, Selhub J, Davignon J, Latour Y, Genest J. Homocysteine and coronary artery disease in French Canadian subjects: Relation with vitamins B12, B6, pyridoxal phosphate, and folate The American Journal of Cardiology. 75: 1107-1111. PMID 7762494 DOI: 10.1016/S0002-9149(99)80739-5  0.39
1995 Bostom AG, Yanek L, Hume AL, Eaton CB, McQuade W, Nadeau M, Perrone G, Jacques PF, Selhub J. High dose ascorbate supplementation fails to affect plasma homocyst(e)ine levels in patients with coronary heart disease. Atherosclerosis. 111: 267-70. PMID 7718029 DOI: 10.1016/0021-9150(94)90101-5  0.364
1994 Miller JW, Nadeau MR, Smith D, Selhub J. Vitamin B-6 deficiency vs folate deficiency: Comparison of responses to methionine loading in rats American Journal of Clinical Nutrition. 59: 1033-1039. PMID 8172087 DOI: 10.1093/Ajcn/59.5.1033  0.422
1994 Miller JW, Nadeau MR, Smith J, Smith D, Selhub J. Folate-deficiency-induced homocysteinaemia in rats: Disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism Biochemical Journal. 298: 415-419. PMID 8135750 DOI: 10.1042/Bj2980415  0.381
1994 Kim YI, Miller JW, da Costa KA, Nadeau M, Smith D, Selhub J, Zeisel SH, Mason JB. Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver. The Journal of Nutrition. 124: 2197-203. PMID 7965204 DOI: 10.1093/Jn/124.11.2197  0.345
1994 Genest J, Lussier-Cacan S, Davignon J, Latour Y, Selhub J. Homocyst(e)ine in health and coronary artery disease in French Canadian men and women: relationship with vitamins B12, B6, pyridoxal phosphate and folate Atherosclerosis. 109: 18. DOI: 10.1016/0021-9150(94)93082-1  0.35
1993 Selhub J, Jacques PF, Rush D, Rosenberg IH, Wilson PWF. Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population Jama: the Journal of the American Medical Association. 270: 2693-2698. PMID 8133587 DOI: 10.1001/Jama.1993.03510220049033  0.504
1992 Selhub J, Miller JW. The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine American Journal of Clinical Nutrition. 55: 131-138. PMID 1728812 DOI: 10.1093/Ajcn/55.1.131  0.326
1992 Miller JW, Ribaya-Mercado JD, Russell RM, Shepard DC, Morrow FD, Cochary EF, Sadowski JA, Gershoff SN, Selhub J. Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations. The American Journal of Clinical Nutrition. 55: 1154-1160. PMID 1595588 DOI: 10.1093/Ajcn/55.6.1154  0.48
1992 Varela-Moreiras G, Selhub J. Long-term folate deficiency alters folate content and distribution differentially in rat tissues Journal of Nutrition. 122: 986-991. PMID 1552373 DOI: 10.1093/Jn/122.4.986  0.334
1992 Varela-Moreiras G, Selhub J, daCosta KA, Zeisel SH. Effect of chronic choline deficiency in rats on liver folate content and distribution The Journal of Nutritional Biochemistry. 3: 519-522. DOI: 10.1016/0955-2863(92)90073-R  0.331
1991 Cravo ML, Mason JB, Selhub J, Rosenberg IH. Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium American Journal of Clinical Nutrition. 53: 1450-1454. PMID 2035472 DOI: 10.1093/Ajcn/53.6.1450  0.343
1980 Selhub J, Ahmad O, Rosenberg IH. Preparation and use of affinity columns with bovine milk folate-binding protein (FBP) covalently linked to Sepharose 4B. Methods in Enzymology. 66: 686-90. PMID 7374508 DOI: 10.1016/0076-6879(80)66528-8  0.317
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