Scott Taylor - Publications

Affiliations: 
Chemistry University of Toronto, Toronto, ON, Canada 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Soley J, Taylor SD. Synthesis of β-Hydroxy-α,α-difluorosulfonamides from Carbanions of Difluoromethanesulfonamides. The Journal of Organic Chemistry. PMID 33847499 DOI: 10.1021/acs.joc.1c00378  0.306
2016 Mc Cluskey GD, Mohamady S, Taylor SD, Bearne SL. Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5'-triphosphate. Chembiochem : a European Journal of Chemical Biology. PMID 27643605 DOI: 10.1002/Cbic.201600405  0.561
2016 McCluskey GD, Mohamady S, Taylor SD, Bearne SL. Cover Picture: Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5′-Triphosphate (ChemBioChem 23/2016) Chembiochem. 17: 2206-2206. DOI: 10.1002/Cbic.201600600  0.565
2010 Kotoris CC, Wen W, Lough A, Taylor SD. ChemInform Abstract: Preparation of Chiral α-Monofluoroalkylphosphonic Acids and Their Evaluation as Inhibitors of Protein Tyrosine Phosphatase 1B. Cheminform. 31: no-no. DOI: 10.1002/chin.200033165  0.787
2010 Taylor SD, Kotoris CC, Hum G. ChemInform Abstract: Recent Advances in Electrophilic Fluorination Cheminform. 31: no-no. DOI: 10.1002/chin.200001268  0.744
2010 Kotoris CC, Chen M, Taylor SD. ChemInform Abstract: Preparation of Benzylic α,α-Difluoronitriles, -tetrazoles, and -sulfonates via Electrophilic Fluorination. Cheminform. 30: no-no. DOI: 10.1002/chin.199912064  0.781
2010 TAYLOR SD, KOTORIS CC, DINAUT AN, CHEN M. ChemInform Abstract: Synthesis of Aryl(difluoromethylenephosphonates) via Electrophilic Fluorination of α-Carbanions of Benzylic Phosphonates with N-Fluorobenzenesulfonimide. Cheminform. 29: no-no. DOI: 10.1002/chin.199825073  0.751
2010 WANG Q, HUANG Z, RAMACHANDRAN C, DINAUT AN, TAYLOR SD. ChemInform Abstract: Naphthalenebis[α,α-difluoromethylenephosphonates] as Potent Inhibitors of Protein Tyrosine Phosphatases. Cheminform. 29: no-no. DOI: 10.1002/chin.199821227  0.788
2010 MA GX, BATEY RA, TAYLOR SD, HUM G, JONES JB. ChemInform Abstract: Synthesis of Dienecarbamates as ADAPT Prodrug Models. Cheminform. 28: no-no. DOI: 10.1002/chin.199738131  0.712
2010 TAYLOR SD, DINAUT AN, THADANI AN, HUANG Z. ChemInform Abstract: Synthesis of Benzylic Mono(α,α-Difluoromethylphosphonates) and Benzylic Bis(α,α-Difluoromethylphosphonates) via Electrophilic Fluorination. Cheminform. 28: no-no. DOI: 10.1002/chin.199708165  0.778
2010 TAYLOR SD, KLUGER R. ChemInform Abstract: Heats of Reaction of Cyclic and Acyclic Phosphate and Phosphonate Esters. “Strain Discrepancy” and Steric Retardation. Cheminform. 23: no-no. DOI: 10.1002/chin.199231229  0.478
2008 Taylor SD, Lunn FA, Bearne SL. Ground state, intermediate, and multivalent nucleotide analogue inhibitors of cytidine 5'-triphosphate synthase. Chemmedchem. 3: 1853-7. PMID 18988211 DOI: 10.1002/Cmdc.200800236  0.55
2008 Taylor SD, Mirzaei F, Bearne SL. Bismethylene triphosphate nucleotides of uridine 4-phosphate analogues: a new class of anionic pyrimidine nucleotide analogues. The Journal of Organic Chemistry. 73: 1403-12. PMID 18215061 DOI: 10.1021/Jo702249J  0.574
2006 Taylor SD, Mirzaei F, Sharifi A, Bearne SL. Synthesis of methylene- and difluoromethylenephosphonate analogues of uridine-4-phosphate and 3-deazauridine-4-phosphate. The Journal of Organic Chemistry. 71: 9420-30. PMID 17137369 DOI: 10.1021/Jo0617666  0.591
2006 Taylor SD, Mirzaei F, Bearne SL. An unsymmetrical approach to the synthesis of bismethylene triphosphate analogues. Organic Letters. 8: 4243-6. PMID 16956197 DOI: 10.1021/Ol0615432  0.587
2003 St Maurice M, Bearne SL, Lu W, Taylor SD. Inhibition of mandelate racemase by alpha-fluorobenzylphosphonates. Bioorganic & Medicinal Chemistry Letters. 13: 2041-4. PMID 12781191 DOI: 10.1016/S0960-894X(03)00311-1  0.547
2002 Hum G, Lee J, Taylor SD. Synthesis of [difluoro-(3-alkenylphenyl)-methyl]-phosphonic acids on non-crosslinked polystyrene and their evaluation as inhibitors of PTP1B. Bioorganic & Medicinal Chemistry Letters. 12: 3471-4. PMID 12419386 DOI: 10.1016/S0960-894X(02)00768-0  0.75
2002 Leung C, Grzyb J, Lee J, Meyer N, Hum G, Jia C, Liu S, Taylor SD. The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors. Bioorganic & Medicinal Chemistry. 10: 2309-23. PMID 11983529 DOI: 10.1016/S0968-0896(02)00062-7  0.71
2001 Jia Z, Ye Q, Dinaut AN, Wang Q, Waddleton D, Payette P, Ramachandran C, Kennedy B, Hum G, Taylor SD. Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics. Journal of Medicinal Chemistry. 44: 4584-94. PMID 11741477 DOI: 10.1021/Jm010266W  0.734
2000 Hum G, Grzyb J, Taylor SD. Synthesis of non-peptidyl alpha,alpha-difluoromethylenephosphonic acids on a soluble polymer support Journal of Combinatorial Chemistry. 2: 234-42. PMID 10827929 DOI: 10.1021/Cc9900596  0.737
2000 Hum G, Wooler K, Lee J, Taylor SD. Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies Canadian Journal of Chemistry. 78: 642-655. DOI: 10.1139/V00-068  0.709
1999 Taylor SD, Kotoris CC, Hum G. Recent advances in electrophilic fluorination Tetrahedron. 55: 12431-12477. DOI: 10.1016/S0040-4020(99)00748-6  0.731
1998 Kotoris CC, Chen MJ, Taylor SD. Novel phosphate mimetics for the design of non-peptidyl inhibitors of protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry Letters. 8: 3275-80. PMID 9873717 DOI: 10.1016/S0960-894X(98)00598-8  0.751
1998 Wang Q, Huang Z, Ramachandran C, Dinaut AN, Taylor SD. Naphthalenebis[alpha,alpha-difluoromethylenephosphonates] as potent inhibitors of protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry Letters. 8: 345-50. PMID 9871682 DOI: 10.1016/S0960-894X(98)00027-4  0.768
1998 Taylor SD, Kotoris CC, Dinaut AN, Wang Q, Ramachandran C, Huang Z. Potent non-peptidyl inhibitors of protein tyrosine phosphatase 1B. Bioorganic & Medicinal Chemistry. 6: 1457-68. PMID 9801817 DOI: 10.1016/S0968-0896(98)00075-3  0.746
1998 Kotoris CC, Chen M, Taylor SD. Preparation of Benzylic α,α-Difluoronitriles, -tetrazoles, and -sulfonates via Electrophilic Fluorination The Journal of Organic Chemistry. 63: 8052-8057. DOI: 10.1021/Jo981163X  0.778
1998 Taylor SD, Kotoris CC, Dinaut A, Chen M. Synthesis of aryl(difluoromethylenephosphonates) via electrophilic fluorination of α-carbanions of benzylic phosphonates with N-fluorobenzenesulfonimide Tetrahedron. 54: 1691-1714. DOI: 10.1016/S0040-4020(97)10395-7  0.788
1994 Hirschmann R, Smith AB, Taylor CM, Benkovic PA, Taylor SD, Yager KM, Sprengeler PA, Benkovic SJ. Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids. Science (New York, N.Y.). 265: 234-7. PMID 8023141 DOI: 10.1126/Science.8023141  0.305
1993 Taylor SD, Kluger R. Hydrolysis of methylacetoin ethyl phosphate. Competing pathways for carbonyl hydrate participation in a model for biotin carboxylation Journal of the American Chemical Society. 115: 867-871. DOI: 10.1021/Ja00056A007  0.491
1992 Taylor SD, Kluger R. Heats of reaction of cyclic and acyclic phosphate and phosphonate esters. Strain discrepancy and steric retardation Journal of the American Chemical Society. 114: 3067-3071. DOI: 10.1021/ja00034a045  0.449
1991 Kluger R, Taylor SD. Endocyclic cleavage in the alkaline hydrolysis of the cyclic phosphonate methyl propylphostonate: dianionic intermediates and barriers to pseudorotation Journal of the American Chemical Society. 113: 5714-5719. DOI: 10.1021/Ja00015A027  0.49
1991 Kluger R, Taylor SD. Mechanisms of carbonyl participation in phosphate ester hydrolysis and their relationship to mechanisms for the carboxylation of biotin Journal of the American Chemical Society. 113: 996-1001. DOI: 10.1021/Ja00003A038  0.479
1990 Kluger R, Taylor SD. On the origins of enhanced reactivity of five-membered cyclic phosphate esters. The relative contributions of enthalpic and entropic factors Journal of the American Chemical Society. 112: 6669-6671. DOI: 10.1021/Ja00174A033  0.512
1990 KLUGER R, TAYLOR SD. ChemInform Abstract: Origins of Enhanced Reactivity of Five-Membered Cyclic Phosphate Esters. The Relative Contributions of Enthalpic and Entropic Factors. Cheminform. 21. DOI: 10.1002/chin.199051078  0.481
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