| Year |
Citation |
Score |
| 2022 |
Jacobson KA, Kim HS, Ravi G, Kim SK, Lee K, Chen A, Chen W, Kim SG, Barak D, Liang BT, Gao ZG. Engineering of A Adenosine and P2Y Nucleotide Receptors and Their Ligands. Drug Development Research. 58: 330-339. PMID 35799977 DOI: 10.1002/ddr.10168 |
0.746 |
|
| 2012 |
Han J, Kim HJ, Lee SC, Hong S, Park K, Jeon YH, Kim D, Cheong HK, Kim HS. Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein. Plos One. 7: e30929. PMID 22363519 DOI: 10.1371/Journal.Pone.0030929 |
0.315 |
|
| 2012 |
Lee SC, Park K, Han J, Lee JJ, Kim HJ, Hong S, Heu W, Kim YJ, Ha JS, Lee SG, Cheong HK, Jeon YH, Kim D, Kim HS. Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering. Proceedings of the National Academy of Sciences of the United States of America. 109: 3299-304. PMID 22328160 DOI: 10.1073/Pnas.1113193109 |
0.3 |
|
| 2004 |
Dunn PM, Kim HS, Jacobson KA, Burnstock G. Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. Drug Development Research. 61: 227-232. PMID 22833693 DOI: 10.1002/Ddr.10381 |
0.368 |
|
| 2004 |
Ohno M, Costanzi S, Kim HS, Kempeneers V, Vastmans K, Herdewijn P, Maddileti S, Gao ZG, Harden TK, Jacobson KA. Nucleotide analogues containing 2-oxa-bicyclo[2.2.1]heptane and l-alpha-threofuranosyl ring systems: interactions with P2Y receptors. Bioorganic & Medicinal Chemistry. 12: 5619-30. PMID 15465340 DOI: 10.1016/J.Bmc.2004.07.067 |
0.6 |
|
| 2003 |
Kim HS, Ohno M, Xu B, Kim HO, Choi Y, Ji XD, Maddileti S, Marquez VE, Harden TK, Jacobson KA. 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists. Journal of Medicinal Chemistry. 46: 4974-87. PMID 14584948 DOI: 10.1021/Jm030127+ |
0.454 |
|
| 2003 |
Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G |
0.312 |
|
| 2003 |
Kim HS, Jacobson KA. Synthesis of a novel conformationally locked carbocyclic nucleoside ring system. Organic Letters. 5: 1665-8. PMID 12735747 DOI: 10.1021/Ol034326Z |
0.312 |
|
| 2002 |
Xu B, Stephens A, Kirschenheuter G, Greslin AF, Cheng X, Sennelo J, Cattaneo M, Zighetti ML, Chen A, Kim SA, Kim HS, Bischofberger N, Cook G, Jacobson KA. Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation. Journal of Medicinal Chemistry. 45: 5694-709. PMID 12477353 DOI: 10.1021/Jm020173U |
0.422 |
|
| 2002 |
Waldo GL, Corbitt J, Boyer JL, Ravi G, Kim HS, Ji XD, Lacy J, Jacobson KA, Harden TK. Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist. Molecular Pharmacology. 62: 1249-57. PMID 12391289 DOI: 10.1124/Mol.62.5.1249 |
0.346 |
|
| 2002 |
Kim SA, Marshall MA, Melman N, Kim HS, Müller CE, Linden J, Jacobson KA. Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of Medicinal Chemistry. 45: 2131-8. PMID 12014951 DOI: 10.1021/Jm0104318 |
0.38 |
|
| 2002 |
Ravi RG, Kim HS, Servos J, Zimmermann H, Lee K, Maddileti S, Boyer JL, Harden TK, Jacobson KA. Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists. Journal of Medicinal Chemistry. 45: 2090-100. PMID 11985476 DOI: 10.1021/Jm010538V |
0.523 |
|
| 2002 |
Kim HS, Ravi RG, Marquez VE, Maddileti S, Wihlborg AK, Erlinge D, Malmsjö M, Boyer JL, Harden TK, Jacobson KA. Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. Journal of Medicinal Chemistry. 45: 208-18. PMID 11754592 DOI: 10.1021/Jm010369E |
0.373 |
|
| 2001 |
Jacobson KA, Ravi RG, Nandanan E, Kim HS, Moro S, Kim YC, Lee K, Barak D, Marquez VE, Ji XD. Ribose modified nucleosides and nucleotides as ligands for purine receptors. Nucleosides, Nucleotides & Nucleic Acids. 20: 333-41. PMID 11563046 DOI: 10.1081/Ncn-100002305 |
0.678 |
|
| 2001 |
Kim HS, Barak D, Harden TK, Boyer JL, Jacobson KA. Acyclic and cyclopropyl analogues of adenosine bisphosphate antagonists of the P2Y1 receptor: structure-activity relationships and receptor docking. Journal of Medicinal Chemistry. 44: 3092-108. PMID 11543678 DOI: 10.1021/Jm010082H |
0.365 |
|
| 2001 |
Ravi G, Lee K, Ji X, Kim HS, Soltysiak KA, Marquez VE, Jacobson KA. Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings. Bioorganic & Medicinal Chemistry Letters. 11: 2295-300. PMID 11527718 DOI: 10.1016/S0960-894X(01)00450-4 |
0.507 |
|
| 2001 |
Jacobson KA, Moro S, Hoffmann C, Kim YC, Kim HS, Ravi RG, Harden TK, Boyer JL. Structurally related nucleotides as selective agonists and antagonists at P2Y1 receptors. Farmaco (Società Chimica Italiana : 1989). 56: 71-5. PMID 11347970 DOI: 10.1016/S0014-827X(01)01023-0 |
0.727 |
|
| 1999 |
Li AH, Ji XD, Kim HS, Melman N, Jacobson KA. Pyran Template Approach to the Design of Novel A3 Adenosine Receptor Antagonists. Drug Development Research. 48: 171-177. PMID 27182099 DOI: 10.1002/(Sici)1098-2299(199912)48:4<171::Aid-Ddr4>3.0.Co;2-5 |
0.358 |
|
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