Kenneth E. Bernstein - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Animal Physiology Biology, Biochemistry

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cao D, Saito S, Xu L, Fan W, Li X, Ahmed F, Jovanovic P, Shibata T, Che M, Bernstein EA, Gianni J, Divakaruni AS, Okwan-Duodu D, Khan Z, Riera CE, ... ... Bernstein KE, et al. Myeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis. Frontiers in Immunology. 14: 1278383. PMID 37928535 DOI: 10.3389/fimmu.2023.1278383  0.721
2023 Cao D, Khan Z, Li X, Saito S, Bernstein EA, Victor AR, Ahmed F, Hoshi AO, Veiras LC, Shibata T, Che M, Cai L, Temel RE, Giani JF, Luthringer DJ, ... ... Bernstein KE, et al. Macrophage angiotensin-converting enzyme (ACE) reduces atherosclerosis by increasing PPARα and fundamentally changing lipid metabolism. Cardiovascular Research. PMID 37225143 DOI: 10.1093/cvr/cvad082  0.707
2022 Suhail H, Peng H, Xu J, Sabbah HN, Matrougui K, Liao TD, Ortiz PA, Bernstein KE, Rhaleb NE. Knockout of ACE-N facilitates improved cardiac function after myocardial infarction. Journal of Molecular and Cellular Cardiology Plus. 3. PMID 36778784 DOI: 10.1016/j.jmccpl.2022.100024  0.364
2022 Saito S, Tatsumoto N, Cao DY, Nosaka N, Nishi H, Leal DN, Bernstein EA, Shimada K, Arditi M, Bernstein KE, Yamashita M. Overexpressed Angiotensin Converting Enzyme in Neutrophils Suppresses Glomerular Damage in Crescentic Glomerulonephritis. American Journal of Physiology. Renal Physiology. PMID 35979968 DOI: 10.1152/ajprenal.00067.2022  0.356
2022 Veiras LC, Bernstein EA, Cao D, Okwan-Duodu D, Khan Z, Gibb DR, Roach A, Skelton R, Williams RM, Bernstein KE, Giani JF. Tubular IL-1β Induces Salt Sensitivity in Diabetes by Activating Renal Macrophages. Circulation Research. 101161CIRCRESAHA1213. PMID 35574842 DOI: 10.1161/CIRCRESAHA.121.320239  0.653
2022 Cao D, Veiras L, Ahmed F, Shibata T, Bernstein EA, Okwan-Duodu D, Giani JF, Khan Z, Bernstein KE. The non-cardiovascular actions of ACE. Peptides. 152: 170769. PMID 35182689 DOI: 10.1016/j.peptides.2022.170769  0.755
2021 Cao DY, Giani JF, Veiras LC, Bernstein EA, Okwan-Duodu D, Ahmed F, Bresee C, Tourtellotte WG, Karumanchi SA, Bernstein KE, Khan Z. An ACE inhibitor reduces bactericidal activity of human neutrophils in vitro and impairs mouse neutrophil activity in vivo. Science Translational Medicine. 13. PMID 34321319 DOI: 10.1126/scitranslmed.abj2138  0.728
2021 Giani JF, Veiras LC, Shen JZY, Bernstein EA, Cao D, Okwan-Duodu D, Khan Z, Gonzalez-Villalobos RA, Bernstein KE. Novel roles of the renal angiotensin-converting enzyme. Molecular and Cellular Endocrinology. 111257. PMID 33781839 DOI: 10.1016/j.mce.2021.111257  0.741
2021 Veiras LC, Shen JZY, Bernstein EA, Regis GC, Cao D, Okwan-Duodu D, Khan Z, Gibb DR, Dominici FP, Bernstein KE, Giani JF. Renal Inflammation Induces Salt Sensitivity in Male db/db Mice through Dysregulation of ENaC. Journal of the American Society of Nephrology : Jasn. PMID 33731332 DOI: 10.1681/ASN.2020081112  0.661
2021 Peng Z, Liu C, Victor AR, Cao DY, Veiras LC, Bernstein EA, Khan Z, Giani JF, Cui X, Bernstein KE, Okwan-Duodu D. Tumors exploit CXCR4CD62L aged neutrophils to facilitate metastatic spread. Oncoimmunology. 10: 1870811. PMID 33537175 DOI: 10.1080/2162402X.2020.1870811  0.635
2020 Dominici FP, Veiras LC, Shen JZY, Bernstein EA, Quiroga DT, Steckelings UM, Bernstein KE, Giani JF. Activation of angiotensin type 2 receptors prevents diabetic complications in female db/db mice by nitric oxide-mediated mechanisms. British Journal of Pharmacology. PMID 32851652 DOI: 10.1111/Bph.15241  0.339
2020 Cao DY, Saito S, Veiras LC, Okwan-Duodu D, Bernstein EA, Giani JF, Bernstein KE, Khan Z. Role of angiotensin-converting enzyme in myeloid cell immune responses. Cellular & Molecular Biology Letters. 25: 31. PMID 32508938 DOI: 10.1186/S11658-020-00225-W  0.759
2020 Veiras LC, Cao D, Saito S, Peng Z, Bernstein EA, Shen JZY, Koronyo-Hamaoui M, Okwan-Duodu D, Giani JF, Khan Z, Bernstein KE. Overexpression of ACE in Myeloid Cells Increases Immune Effectiveness and Leads to a New Way of Considering Inflammation in Acute and Chronic Diseases. Current Hypertension Reports. 22: 4. PMID 31916032 DOI: 10.1007/S11906-019-1008-X  0.736
2020 Veiras LC, Shen JZ, Bernstein EA, Okwan-Duodu D, Khan Z, Cao D, Dominici FP, Bernstein KE, Giani JF. Abstract P008: Sex Differences In The Development Of Diabetic Kidney Disease And Salt Sensitivity In Db/db Mice Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P008  0.689
2019 Cao DY, Spivia WR, Veiras LC, Khan Z, Peng Z, Jones AE, Bernstein EA, Saito S, Okwan-Duodu D, Parker SJ, Giani JF, Divakaruni AS, Van Eyk JE, Bernstein KE. ACE over expression in myeloid cells increases oxidative metabolism and cellular ATP. The Journal of Biological Chemistry. PMID 31871049 DOI: 10.1074/Jbc.Ra119.011244  0.745
2019 Koronyo-Hamaoui M, Sheyn J, Hayden EY, Li S, Fuchs DT, Regis GC, Lopes DHJ, Black KL, Bernstein KE, Teplow DB, Fuchs S, Koronyo Y, Rentsendorj A. Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease. Brain : a Journal of Neurology. PMID 31794021 DOI: 10.1093/Brain/Awz364  0.382
2019 Okwan-Duodu D, Weiss D, Peng Z, Veiras LC, Cao DY, Saito S, Khan Z, Bernstein EA, Giani JF, Taylor WR, Bernstein KE. Overexpression of myeloid angiotensin-converting enzyme (ACE) reduces atherosclerosis. Biochemical and Biophysical Research Communications. PMID 31615657 DOI: 10.1016/J.Bbrc.2019.10.078  0.737
2019 Zhao TV, Li Y, Liu X, Xia S, Shi P, Li L, Chen Z, Yin C, Eriguchi M, Chen Y, Bernstein EA, Giani JF, Bernstein KE, Shen XZ. ATP release drives heightened immune responses associated with hypertension. Science Immunology. 4. PMID 31253642 DOI: 10.1126/Sciimmunol.Aau6426  0.41
2019 Semis M, Gugiu G, Bernstein EA, Bernstein KE, Kalkum M. The Plethora of Angiotensin-Converting Enzyme-processed Peptides in Mouse Plasma. Analytical Chemistry. PMID 31021607 DOI: 10.1021/Acs.Analchem.8B03828  0.497
2019 Khan Z, Cao DY, Giani JF, Bernstein EA, Veiras LC, Fuchs S, Wang Y, Peng Z, Kalkum M, Liu GY, Bernstein KE. Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization. The Journal of Biological Chemistry. PMID 30670595 DOI: 10.1074/Jbc.Ra118.006275  0.505
2019 Shen JZ, Hernandez A, Bernstein EA, Veiras LC, Khan Z, Cao D, McDonough AA, Bernstein KE, Giani JF. Abstract P3034: Female Mice are Protected Against Renal Inflammation and Salt-Sensitive Hypertension During Diabetes Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P3034  0.347
2018 Eriguchi M, Bernstein EA, Veiras LC, Khan Z, Cao DY, Fuchs S, McDonough AA, Toblli JE, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 30185469 DOI: 10.1681/Asn.2018030323  0.451
2018 Tan WQ, Fang QQ, Shen XZ, Giani JF, Zhao TV, Shi P, Zhang LY, Khan Z, Li Y, Li L, Xu JH, Bernstein E, Bernstein KE. Angiotensin-converting enzyme inhibitor works as a scar formation inhibitor by downregulating Smad and TAK1 pathways in mice. British Journal of Pharmacology. PMID 30153328 DOI: 10.1111/Bph.14489  0.428
2018 Bernstein KE, Khan Z, Giani JF, Cao DY, Bernstein EA, Shen XZ. Angiotensin-converting enzyme in innate and adaptive immunity. Nature Reviews. Nephrology. PMID 29578208 DOI: 10.1038/Nrneph.2018.15  0.53
2018 Zhao T, Zhu Q, Li Y, Liu X, Shi P, Bernstein KE, Shen XZ. Abstract 130: ATP Release Drives the Immune Responses Associated With Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.130  0.346
2018 Giani JF, Eriguchi M, Bernstein EA, Veiras LC, Khan Z, Cao DY, Fuchs S, McDonough AA, Toblli JE, Gonzalez-Villalobos RA, Bernstein KE. Abstract 035: Increasing Renal AcSDKP by Eliminating the ACE N-Domain Blocks Renal Inflammation and Sodium Retention During Diabetic Nephropathy Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.035  0.333
2017 O'Reilly PJ, Ding Q, Akthar S, Cai G, Genschmer KR, Patel DF, Jackson PL, Viera L, Roda M, Locy ML, Bernstein EA, Lloyd CM, Bernstein KE, Snelgrove RJ, Blalock JE. Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis. Jci Insight. 2. PMID 29202450 DOI: 10.1172/Jci.Insight.91923  0.352
2017 Eriguchi M, Lin M, Yamashita M, Zhao TV, Khan Z, Bernstein EA, Gurley SB, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. Renal tubular ACE-mediated tubular injury is the major contributor to microalbuminuria in early diabetic nephropathy. American Journal of Physiology. Renal Physiology. ajprenal.00523.2017. PMID 29187372 DOI: 10.1152/Ajprenal.00523.2017  0.429
2017 Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke. PMID 28698257 DOI: 10.1161/Strokeaha.117.017370  0.312
2017 Khan Z, Shen XZ, Bernstein EA, Giani JF, Eriguchi M, Zhao TV, Gonzalez-Villalobos RA, Fuchs S, Liu GY, Bernstein KE. Angiotensin converting enzyme enhances the oxidative response and bactericidal activity of neutrophils. Blood. PMID 28515091 DOI: 10.1182/Blood-2016-11-752006  0.509
2017 Zhao T, Bernstein KE, Fang J, Shen XZ. Angiotensin-converting enzyme affects the presentation of MHC class II antigens. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 28394320 DOI: 10.1038/Labinvest.2017.32  0.478
2016 Giani JF, Eriguchi M, Bernstein EA, Katsumata M, Shen XZ, Li L, McDonough AA, Fuchs S, Bernstein KE, Gonzalez-Villalobos RA. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity. Kidney International. PMID 27988209 DOI: 10.1016/J.Kint.2016.10.007  0.483
2016 Bernstein KE, Khan Z, Giani JF, Zhao T, Eriguchi M, Bernstein EA, Gonzalez-Villalobos RA, Shen XZ. Overexpression of angiotensin-converting enzyme in myelomonocytic cells enhances the immune response. F1000research. 5. PMID 27018193 DOI: 10.12688/F1000Research.7508.1  0.511
2016 Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, ... ... Bernstein KE, et al. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circulation Research. PMID 26988069 DOI: 10.1161/Circresaha.115.308111  0.327
2015 Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, et al. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of Clinical Investigation. PMID 26595812 DOI: 10.1172/Jci80761  0.414
2015 Shah KH, Shi P, Giani JF, Janjulia T, Bernstein E, Li Y, Zhao T, Harrison DG, Bernstein KE, Shen XZ. Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension. Circulation Research. PMID 26294657 DOI: 10.1161/Circresaha.115.306539  0.362
2015 Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA. Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme. Hypertension. PMID 26150439 DOI: 10.1161/Hypertensionaha.115.05320  0.424
2015 Shen XZ, Li Y, Li L, Shah KH, Bernstein KE, Lyden P, Shi P. Microglia Participate in Neurogenic Regulation of Hypertension. Hypertension. PMID 26056339 DOI: 10.1161/Hypertensionaha.115.05333  0.422
2015 Garcia V, Joseph G, Shkolnik B, Ding Y, Zhang FF, Gotlinger K, Falck JR, Dakarapu R, Capdevila JH, Bernstein KE, Schwartzman ML. Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R71-8. PMID 25924878 DOI: 10.1152/Ajpregu.00039.2015  0.492
2015 Giani JF, Shah KH, Khan Z, Bernstein EA, Shen XZ, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE. The intrarenal generation of angiotensin II is required for experimental hypertension. Current Opinion in Pharmacology. 21: 73-81. PMID 25616034 DOI: 10.1016/J.Coph.2015.01.002  0.478
2014 Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, ... ... Bernstein KE, et al. DC isoketal-modified proteins activate T cells and promote hypertension. The Journal of Clinical Investigation. 124: 4642-56. PMID 25244096 DOI: 10.1172/Jci74084  0.351
2014 Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA. Renal generation of angiotensin II and the pathogenesis of hypertension. Current Hypertension Reports. 16: 477. PMID 25097114 DOI: 10.1007/S11906-014-0477-1  0.421
2014 Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WL, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos RA. Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition. Journal of the American Society of Nephrology : Jasn. 25: 2752-63. PMID 25012170 DOI: 10.1681/Asn.2013091030  0.483
2014 Koronyo-Hamaoui M, Shah K, Koronyo Y, Bernstein E, Giani JF, Janjulia T, Black KL, Shi PD, Gonzalez-Villalobos RA, Fuchs S, Shen XZ, Bernstein KE. ACE overexpression in myelomonocytic cells: effect on a mouse model of Alzheimer's disease. Current Hypertension Reports. 16: 444. PMID 24792094 DOI: 10.1007/S11906-014-0444-X  0.485
2014 Bernstein KE, Gonzalez-Villalobos RA, Giani JF, Shah K, Bernstein E, Janjulia T, Koronyo Y, Shi PD, Koronyo-Hamaoui M, Fuchs S, Shen XZ. Angiotensin-converting enzyme overexpression in myelocytes enhances the immune response. Biological Chemistry. 395: 1173-8. PMID 24633750 DOI: 10.1515/Hsz-2013-0295  0.526
2014 Shen XZ, Okwan-Duodu D, Blackwell WL, Ong FS, Janjulia T, Bernstein EA, Fuchs S, Alkan S, Bernstein KE. Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 536-44. PMID 24614194 DOI: 10.1038/Labinvest.2014.41  0.757
2014 Bernstein KE, Koronyo Y, Salumbides BC, Sheyn J, Pelissier L, Lopes DH, Shah KH, Bernstein EA, Fuchs DT, Yu JJ, Pham M, Black KL, Shen XZ, Fuchs S, Koronyo-Hamaoui M. Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline. The Journal of Clinical Investigation. 124: 1000-12. PMID 24487585 DOI: 10.1172/Jci66541  0.411
2014 Bernstein KE, Giani JF, Shen XZ, Gonzalez-Villalobos RA. Renal angiotensin-converting enzyme and blood pressure control. Current Opinion in Nephrology and Hypertension. 23: 106-12. PMID 24378774 DOI: 10.1097/01.Mnh.0000441047.13912.56  0.436
2014 Koronyo-Hamaoui M, Koronyo Y, Salumbides BC, Sheyn J, Fuchs DS, Pelissier L, Bernstein EA, Black KL, Shen XZ, Fuchs S, Bernstein KE. P3-417: TARGETING ACE-AN ENZYME THAT CONTROLS BLOOD PRESSURE-TO MYELOMONOCYTES PREVENTS ALZHEIMER'S-LIKE PATHOLOGY AND COGNITIVE DECLINE Alzheimer's & Dementia. 10: P783-P783. DOI: 10.1016/J.Jalz.2014.05.1512  0.35
2013 Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, Janjulia T, Taylor B, Giani JF, Blackwell WL, Shah KH, Shi PD, Fuchs S, Bernstein KE. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. Journal of Molecular Medicine (Berlin, Germany). 91: 1143-54. PMID 23686164 DOI: 10.1007/S00109-013-1051-Z  0.511
2013 Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, et al. The absence of intrarenal ACE protects against hypertension. The Journal of Clinical Investigation. 123: 2011-23. PMID 23619363 DOI: 10.1172/Jci65460  0.509
2013 Grobe N, Weir NM, Leiva O, Ong FS, Bernstein KE, Schmaier AH, Morris M, Elased KM. Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry. American Journal of Physiology. Cell Physiology. 304: C945-53. PMID 23392115 DOI: 10.1152/Ajpcell.00346.2012  0.464
2013 Bernstein KE, Ong FS, Blackwell WL, Shah KH, Giani JF, Gonzalez-Villalobos RA, Shen XZ, Fuchs S, Touyz RM. A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme. Pharmacological Reviews. 65: 1-46. PMID 23257181 DOI: 10.1124/Pr.112.006809  0.472
2012 Shen XZ, Ong FS, Bernstein EA, Janjulia T, Blackwell WLB, Shah KH, Taylor BL, Gonzalez-Villalobos RA, Fuchs S, Bernstein KE. Nontraditional roles of angiotensin-converting enzyme Hypertension. 59: 763-768. PMID 22353608 DOI: 10.1161/Hypertensionaha.111.188342  0.469
2012 Ong FS, Lin CX, Campbell DJ, Okwan-Duodu D, Chen X, Blackwell WL, Shah KH, Gonzalez-Villalobos RA, Shen XZ, Fuchs S, Bernstein KE. Increased angiotensin II-induced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity. Hypertension. 59: 283-90. PMID 22203735 DOI: 10.1161/Hypertensionaha.111.180844  0.76
2012 Koronyo-Hamaoui M, Salumbides B, Koronyo Y, Sheyn J, Pelissier L, Yu J, Bernstein E, Shen X, Fuchs D, Pham M, Black K, Fuchs S, Bernstein K. P3-348: Targeted high-expression of ACE to myelomonocytic cells diminishes Alzheimer's-like pathology and restores memory and learning in mouse models Alzheimer's & Dementia. 8: P579-P579. DOI: 10.1016/J.Jalz.2012.05.2170  0.451
2011 Sovari AA, Iravanian S, Dolmatova E, Jiao Z, Liu H, Zandieh S, Kumar V, Wang K, Bernstein KE, Bonini MG, Duffy HS, Dudley SC. Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death. Journal of the American College of Cardiology. 58: 2332-9. PMID 22093512 DOI: 10.1016/J.Jacc.2011.07.048  0.36
2011 Shen XZ, Billet S, Lin C, Okwan-Duodu D, Chen X, Lukacher AE, Bernstein KE. The carboxypeptidase ACE shapes the MHC class I peptide repertoire. Nature Immunology. 12: 1078-85. PMID 21964607 DOI: 10.1038/Ni.2107  0.708
2011 Iravanian S, Sovari AA, Lardin HA, Liu H, Xiao HD, Dolmatova E, Jiao Z, Harris BS, Witham EA, Gourdie RG, Duffy HS, Bernstein KE, Dudley SC. Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43. Journal of Molecular Medicine (Berlin, Germany). 89: 677-87. PMID 21553032 DOI: 10.1007/S00109-011-0761-3  0.445
2011 Shen XZ, Bernstein KE. The peptide network regulated by angiotensin converting enzyme (ACE) in hematopoiesis. Cell Cycle (Georgetown, Tex.). 10: 1363-9. PMID 21441775 DOI: 10.4161/Cc.10.9.15444  0.41
2011 Lin C, Datta V, Okwan-Duodu D, Chen X, Fuchs S, Alsabeh R, Billet S, Bernstein KE, Shen XZ. Angiotensin-converting enzyme is required for normal myelopoiesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1145-55. PMID 21148418 DOI: 10.1096/Fj.10-169433  0.778
2011 Bernstein KE, Shen XZ, Gonzalez-Villalobos RA, Billet S, Okwan-Duodu D, Ong FS, Fuchs S. Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE). Current Opinion in Pharmacology. 11: 105-11. PMID 21130035 DOI: 10.1016/J.Coph.2010.11.001  0.724
2011 Gonzalez-Villalobos RA, Billet S, Kim C, Satou R, Fuchs S, Bernstein KE, Navar LG. Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. Journal of the American Society of Nephrology : Jasn. 22: 449-59. PMID 21115616 DOI: 10.1681/Asn.2010060624  0.547
2010 Okwan-Duodu D, Datta V, Shen XZ, Goodridge HS, Bernstein EA, Fuchs S, Liu GY, Bernstein KE. Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus. The Journal of Biological Chemistry. 285: 39051-60. PMID 20937811 DOI: 10.1074/Jbc.M110.163782  0.751
2010 Li P, Xiao HD, Xu J, Ong FS, Kwon M, Roman J, Gal A, Bernstein KE, Fuchs S. Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury. The American Journal of Pathology. 177: 1113-21. PMID 20651228 DOI: 10.2353/Ajpath.2010.081127  0.39
2010 Bernstein KE, Fuchs S. Angiotensin II and JAK2 put on the pressure. Nature Medicine. 16: 165-6. PMID 20134469 DOI: 10.1038/Nm0210-165  0.404
2010 Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC. Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Circulation. 121: 519-28. PMID 20083682 DOI: 10.1161/Circulationaha.109.883777  0.318
2010 Weiss D, Bernstein KE, Fuchs S, Adams J, Synetos A, Taylor WR. Vascular wall ACE is not required for atherogenesis in ApoE(-/-) mice. Atherosclerosis. 209: 352-8. PMID 19880118 DOI: 10.1016/J.Atherosclerosis.2009.09.069  0.513
2009 Campbell DJ, Xiao HD, Fuchs S, Bernstein KE. Genetic models provide unique insight into angiotensin and bradykinin peptides in the extravascular compartment of the heart in vivo. Clinical and Experimental Pharmacology & Physiology. 36: 547-53. PMID 19673938 DOI: 10.1111/J.1440-1681.2008.05106.X  0.484
2008 Shen XZ, Xiao HD, Li P, Lin CX, Billet S, Okwan-Duodu D, Adams JW, Bernstein EA, Xu Y, Fuchs S, Bernstein KE. New insights into the role of angiotensin-converting enzyme obtained from the analysis of genetically modified mice. Journal of Molecular Medicine (Berlin, Germany). 86: 679-84. PMID 18443752 DOI: 10.1007/S00109-008-0325-3  0.773
2008 Shen XZ, Lukacher AE, Billet S, Williams IR, Bernstein KE. Expression of angiotensin-converting enzyme changes major histocompatibility complex class I peptide presentation by modifying C termini of peptide precursors. The Journal of Biological Chemistry. 283: 9957-65. PMID 18252713 DOI: 10.1074/Jbc.M709574200  0.421
2008 Shen XZ, Xiao HD, Li P, Billet S, Lin CX, Fuchs S, Bernstein KE. Tissue specific expression of angiotensin converting enzyme: a new way to study an old friend. International Immunopharmacology. 8: 171-6. PMID 18182222 DOI: 10.1016/J.Intimp.2007.08.010  0.548
2008 Fuchs S, Xiao HD, Hubert C, Michaud A, Campbell DJ, Adams JW, Capecchi MR, Corvol P, Bernstein KE. Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo. Hypertension. 51: 267-74. PMID 18158355 DOI: 10.1161/Hypertensionaha.107.097865  0.513
2008 Xiao HD, Fuchs S, Bernstein EA, Li P, Campbell DJ, Bernstein KE. Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 294: H659-67. PMID 18032521 DOI: 10.1152/Ajpheart.01147.2007  0.464
2008 Shen XZ, Xiao HD, Li P, Lin CX, Fuchs S, Bernstein KE. Corrigendum to "Tissue specific expression of angiotensin converting enzyme: A new way to study an old friend" [International Immunopharmacology (2008) 8, 171-176] (DOI:10.1016/j.intimp.2007.08.010) International Immunopharmacology. 8: 1065. DOI: 10.1016/J.Intimp.2008.03.014  0.389
2007 Billet S, Bardin S, Verp S, Baudrie V, Michaud A, Conchon S, Muffat-Joly M, Escoubet B, Souil E, Hamard G, Bernstein KE, Gasc JM, Elghozi JL, Corvol P, Clauser E. Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice. The Journal of Clinical Investigation. 117: 1914-25. PMID 17607364 DOI: 10.1172/Jci28764  0.435
2007 Shen XZ, Li P, Weiss D, Fuchs S, Xiao HD, Adams JA, Williams IR, Capecchi MR, Taylor WR, Bernstein KE. Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma. The American Journal of Pathology. 170: 2122-34. PMID 17525278 DOI: 10.2353/Ajpath.2007.061205  0.472
2007 Reudelhuber TL, Bernstein KE, Delafontaine P. Is angiotensin II a direct mediator of left ventricular hypertrophy? Time for another look. Hypertension. 49: 1196-201. PMID 17452509 DOI: 10.1161/Hypertensionaha.106.075085  0.337
2007 Kasi VS, Xiao HD, Shang LL, Iravanian S, Langberg J, Witham EA, Jiao Z, Gallego CJ, Bernstein KE, Dudley SC. Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation. American Journal of Physiology. Heart and Circulatory Physiology. 293: H182-92. PMID 17337599 DOI: 10.1152/Ajpheart.00684.2006  0.42
2006 Eckman EA, Adams SK, Troendle FJ, Stodola BA, Kahn MA, Fauq AH, Xiao HD, Bernstein KE, Eckman CB. Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme. The Journal of Biological Chemistry. 281: 30471-8. PMID 16912050 DOI: 10.1074/Jbc.M605827200  0.364
2006 Frenzel K, Wallace TA, McDoom I, Xiao HD, Capecchi MR, Bernstein KE, Sayeski PP. A functional Jak2 tyrosine kinase domain is essential for mouse development. Experimental Cell Research. 312: 2735-44. PMID 16887119 DOI: 10.1016/J.Yexcr.2006.05.004  0.317
2006 Wysocki J, Ye M, Soler MJ, Gurley SB, Xiao HD, Bernstein KE, Coffman TM, Chen S, Batlle D. ACE and ACE2 activity in diabetic mice. Diabetes. 55: 2132-9. PMID 16804085 DOI: 10.2337/Db06-0033  0.425
2006 Bernstein KE. Views of the renin-angiotensin system: brilling, mimsy, and slithy tove. Hypertension. 47: 509-14. PMID 16365193 DOI: 10.1161/01.Hyp.0000196266.23639.C6  0.525
2005 Fuchs S, Frenzel K, Hubert C, Lyng R, Muller L, Michaud A, Xiao HD, Adams JW, Capecchi MR, Corvol P, Shur BD, Bernstein KE. Male fertility is dependent on dipeptidase activity of testis ACE. Nature Medicine. 11: 1140-2; author reply. PMID 16270063 DOI: 10.1038/Nm1105-1140  0.315
2005 Bernstein KE, Xiao HD, Frenzel K, Li P, Shen XZ, Adams JW, Fuchs S. Six truisms concerning ACE and the renin-angiotensin system educed from the genetic analysis of mice. Circulation Research. 96: 1135-44. PMID 15947253 DOI: 10.1161/01.Res.0000169536.73576.66  0.508
2005 Gletsu N, Doan TN, Cole J, Sutliff RL, Bernstein KE. Angiotensin II-induced hypertension in mice caused an increase in insulin secretion. Vascular Pharmacology. 42: 83-92. PMID 15792925 DOI: 10.1016/J.Vph.2005.01.006  0.598
2005 Bernstein KE, Xiao HD, Adams JW, Frenzel K, Li P, Shen XZ, Cole JM, Fuchs S. Establishing the role of angiotensin-converting enzyme in renal function and blood pressure control through the analysis of genetically modified mice. Journal of the American Society of Nephrology : Jasn. 16: 583-91. PMID 15659560 DOI: 10.1681/Asn.2004080693  0.664
2005 Hashimoto S, Adams JW, Bernstein KE, Schnermann J. Micropuncture determination of nephron function in mice without tissue angiotensin-converting enzyme. American Journal of Physiology. Renal Physiology. 288: F445-52. PMID 15494545 DOI: 10.1152/Ajprenal.00297.2004  0.514
2004 Xiao HD, Fuchs S, Campbell DJ, Lewis W, Dudley SC, Kasi VS, Hoit BD, Keshelava G, Zhao H, Capecchi MR, Bernstein KE. Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. The American Journal of Pathology. 165: 1019-32. PMID 15331425 DOI: 10.1016/S0002-9440(10)63363-9  0.447
2004 Xiao HD, Fuchs S, Frenzel K, Teng L, Li P, Shen XZ, Adams J, Zhao H, Keshelava GT, Bernstein KE, Cole JM. The use of knockout mouse technology to achieve tissue selective expression of angiotensin converting enzyme. Journal of Molecular and Cellular Cardiology. 36: 781-9. PMID 15158118 DOI: 10.1016/J.Yjmcc.2004.02.013  0.675
2004 Xiao HD, Fuchs S, Frenzel K, Teng L, Bernstein KE. Circulating versus local angiotensin II in blood pressure control: lessons from tissue-specific expression of angiotensin-converting enzyme (ACE). Critical Reviews in Eukaryotic Gene Expression. 14: 137-45. PMID 15104531  0.381
2004 Fuchs S, Frenzel K, Xiao HD, Adams JW, Zhao H, Keshelava G, Teng L, Bernstein KE. Newly recognized physiologic and pathophysiologic actions of the angiotensin-converting enzyme. Current Hypertension Reports. 6: 124-8. PMID 15010016 DOI: 10.1007/S11906-004-0087-4  0.479
2004 Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, Bernstein KE, Chappell MC. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension. 43: 849-53. PMID 14981053 DOI: 10.1161/01.Hyp.0000121462.27393.F6  0.527
2004 Campbell DJ, Alexiou T, Xiao HD, Fuchs S, McKinley MJ, Corvol P, Bernstein KE. Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice. Hypertension. 43: 854-9. PMID 14769811 DOI: 10.1161/01.Hyp.0000119190.06968.F1  0.534
2004 Fuchs S, Xiao HD, Cole JM, Adams JW, Frenzel K, Michaud A, Zhao H, Keshelava G, Capecchi MR, Corvol P, Bernstein KE. Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. The Journal of Biological Chemistry. 279: 15946-53. PMID 14757757 DOI: 10.1074/Jbc.M400149200  0.68
2004 Xiao HD, Fuchs S, Frenzel K, Teng L, Bernstein KE. Circulating versus local angiotensin II in blood pressure control: lessons from tissue-specific expression of angiotensin-converting enzyme (ACE). Critical Reviews in Eukaryotic Gene Expression. 14: 137-146. DOI: 10.1615/Critreveukaryotgeneexpr.V14.I12.70  0.481
2003 Xiao HD, Fuchs S, Frenzel K, Cole JM, Bernstein KE. Newer approaches to genetic modeling in mice: tissue-specific protein expression as studied using angiotensin-converting enzyme (ACE). The American Journal of Pathology. 163: 807-17. PMID 12937122 DOI: 10.1016/S0002-9440(10)63441-4  0.569
2003 Xiao HD, Fuchs S, Cole JM, Disher KM, Sutliff RL, Bernstein KE. Role of bradykinin in angiotensin-converting enzyme knockout mice. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1969-77. PMID 12637363 DOI: 10.1152/Ajpheart.00010.2003  0.702
2003 Cole JM, Xiao H, Adams JW, Disher KM, Zhao H, Bernstein KE. New approaches to genetic manipulation of mice: tissue-specific expression of ACE. American Journal of Physiology. Renal Physiology. 284: F599-607. PMID 12620918 DOI: 10.1152/Ajprenal.00308.2002  0.671
2003 Cole JM, Khokhlova N, Sutliff RL, Adams JW, Disher KM, Zhao H, Capecchi MR, Corvol P, Bernstein KE. Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II. Hypertension. 41: 313-21. PMID 12574101 DOI: 10.1161/01.Hyp.0000050650.52007.83  0.694
2002 Klein JD, Le Quach D, Cole JM, Disher K, Mongiu AK, Wang X, Bernstein KE, Sands JM. Impaired urine concentration and absence of tissue ACE: involvement of medullary transport proteins. American Journal of Physiology. Renal Physiology. 283: F517-24. PMID 12167603 DOI: 10.1152/Ajprenal.00326.2001  0.642
2002 Dzau VJ, Bernstein K, Celermajer D, Cohen J, Dahlöf B, Deanfield J, Diez J, Drexler H, Ferrari R, Van Gilst W, Hansson L, Hornig B, Husain A, Johnston C, Lazar H, et al. Pathophysiologic and therapeutic importance of tissue ACE: a consensus report. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 16: 149-60. PMID 12090908 DOI: 10.1023/A:1015709617405  0.426
2002 Bernstein KE. Two ACEs and a heart. Nature. 417: 799-802. PMID 12075331 DOI: 10.1038/417799A  0.304
2002 Cole J, Quach DL, Sundaram K, Corvol P, Capecchi MR, Bernstein KE. Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure. Circulation Research. 90: 87-92. PMID 11786523 DOI: 10.1161/Hh0102.102360  0.703
2001 Sayeski PP, Bernstein KE. Signal transduction mechanisms of the angiotensin II type AT1-receptor: Looking beyond the heterotrimeric G protein paradigm Jraas - Journal of the Renin-Angiotensin-Aldosterone System. 2: 4-10. PMID 11881054 DOI: 10.3317/Jraas.2001.007  0.402
2001 Bernstein KE, Sayeski PP, Doan T, Farmer PK, Ali MS. Signal transduction pathways of angiotensin II in the kidney. Contributions to Nephrology. 16-33. PMID 11705281 DOI: 10.1159/000060168  0.347
2001 Dzau VJ, Bernstein K, Celermajer D, Cohen J, Dahlöf B, Deanfield J, Diez J, Drexler H, Ferrari R, van Gilst W, Hansson L, Hornig B, Husain A, Johnston C, Lazar H, et al. The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data. The American Journal of Cardiology. 88: 1L-20L. PMID 11694220 DOI: 10.1016/S0002-9149(01)01878-1  0.469
2001 Doan TN, Gletsu N, Cole J, Bernstein KE. Genetic manipulation of the renin-angiotensin system. Current Opinion in Nephrology and Hypertension. 10: 483-91. PMID 11458029 DOI: 10.1097/00041552-200107000-00002  0.691
2001 Doan TN, Ali MS, Bernstein KE. Tyrosine kinase activation by the angiotensin II receptor in the absence of calcium signaling. The Journal of Biological Chemistry. 276: 20954-8. PMID 11319216 DOI: 10.1074/Jbc.C100199200  0.33
2001 Sayeski PP, Showkat Ali M, Frank SJ, Bernstein KE. The Angiotensin II-dependent Nuclear Translocation of Stat1 is Mediated by the Jak2 Protein Motif 231YRFRR Journal of Biological Chemistry. 276: 10556-10563. PMID 11152457 DOI: 10.1074/Jbc.M008856200  0.352
2000 Cole J, Ertoy D, Bernstein KE. Insights derived from ACE knockout mice Jraas - Journal of the Renin-Angiotensin-Aldosterone System. 1: 137-141. PMID 11967804 DOI: 10.3317/Jraas.2000.016  0.619
2000 Sayeski PP, Ali MS, Bernstein KE. The role of Ca2+ mobilization and heterotrimeric G protein activation in mediating tyrosine phosphorylation signaling patterns in vascular smooth muscle cells Molecular and Cellular Biochemistry. 212: 91-98. PMID 11108140 DOI: 10.1007/978-1-4615-4351-0_11  0.328
2000 Cole J, Ertoy D, Lin H, Sutliff RL, Ezan E, Guyene TT, Capecchi M, Corvol P, Bernstein KE. Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice Journal of Clinical Investigation. 106: 1391-1398. PMID 11104792 DOI: 10.1172/Jci10557  0.691
2000 Ali MS, Sayeski PP, Bernstein KE. Jak2 acts as both a STAT1 kinase and as a molecular bridge linking STAT1 to the angiotensin II AT1 receptor Journal of Biological Chemistry. 275: 15586-15593. PMID 10748109 DOI: 10.1074/Jbc.M908931199  0.314
2000 Cole JM, Corvol P, Bernstein KE. Evaluation of Anemia in Angiotensin Converting Enzyme (ACE) Knockout Mice. Hypertension. 36: 693-693. DOI: 10.1161/01.Hyp.36.Suppl_1.693-A  0.677
1999 Bunting M, Bernstein KE, Greer JM, Capecchi MR, Thomas KR. Targeting genes for self-excision in the germ line. Genes & Development. 13: 1524-8. PMID 10385621 DOI: 10.1101/Gad.13.12.1524  0.329
1999 Sayeski PP, Ali MS, Hawks K, Frank SJ, Bernstein KE. The angiotensin II-dependent association of Jak2 and c-Src requires the N-terminus of Jak2 and the SH2 domain of c-Src Circulation Research. 84: 1332-1338. PMID 10364571 DOI: 10.1161/01.Res.84.11.1332  0.324
1998 Bernstein KE, Esther CR. The functional role of angiotensin-converting enzyme as explored by using knockout mice Advances in Nephrology From the Necker Hospital. 28: 213-223. PMID 9889992  0.375
1998 Sayeski PP, Ali MS, Semeniuk DJ, Doan TN, Bernstein KE. Angiotensin II signal transduction pathways. Regulatory Peptides. 78: 19-29. PMID 9879743 DOI: 10.1016/S0167-0115(98)00137-2  0.377
1998 Bernstein KE. The role of tissue angiotensin-converting enzyme (ACE): Studies of ACE mutant mice American Journal of Cardiology. 82. PMID 9860346 DOI: 10.1016/S0002-9149(98)00668-7  0.505
1998 Bernstein KE. Examining the renin-angiotensin system one hundred years after its discovery Nephrologie. 19: 391-395. PMID 9857373  0.414
1997 Ali MS, Sayeski PP, Dirksen LB, Hayzer DJ, Marrero MB, Bernstein KE. Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor Journal of Biological Chemistry. 272: 23382-23388. PMID 9287353 DOI: 10.1074/Jbc.272.37.23382  0.301
1997 Esther CR, Marino EM, Howard TE, Machaud A, Corvol P, Capecchi MR, Bernstein KE. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. The Journal of Clinical Investigation. 99: 2375-85. PMID 9153279 DOI: 10.1172/Jci119419  0.548
1997 Ali MS, Schieffer B, Delafontaine P, Bernstein KE, Ling BN, Marrero MB. Angiotensin II stimulates tyrosine phosphorylation and activation of insulin receptor substrate 1 and protein-tyrosine phosphatase 1D in vascular smooth muscle cells Journal of Biological Chemistry. 272: 12373-12379. PMID 9139682 DOI: 10.1074/Jbc.272.19.12373  0.327
1997 Harp JB, Sayeski PP, Scanlon M, Bernstein KE, Marrero MB. Role of intracellular calcium in the angiotensin II-mediated tyrosine phosphorylation and dephosphorylation of PLC-γl Biochemical and Biophysical Research Communications. 232: 540-544. PMID 9125218 DOI: 10.1006/Bbrc.1997.6322  0.301
1997 Esther CR, Marino EM, Bernstein KE. The role of angiotensin-converting enzyme in blood pressure control, renal function, and male fertility Trends in Endocrinology and Metabolism. 8: 181-186. DOI: 10.1016/S1043-2760(97)00039-8  0.486
1996 Esther CR, Howard TE, Zhou Y, Capecchi MR, Marrero MB, Bernstein KE. Lessons from angiotensin-converting enzyme-deficient mice. Current Opinion in Nephrology and Hypertension. 5: 463-7. PMID 8978990 DOI: 10.1097/00041552-199611000-00001  0.469
1996 Schieffer B, Bernstein KE, Marrero MB. The role of tyrosine phosphorylation in angiotensin II mediated intracellular signaling and cell growth Journal of Molecular Medicine. 74: 85-91. PMID 8820403 DOI: 10.1007/Bf00196783  0.349
1996 Marrero MB, Paxton WG, Schieffer B, Ling BN, Bernstein KE. Angiotensin II signalling events mediated by tyrosine phosphorylation Cellular Signalling. 8: 21-26. PMID 8777137 DOI: 10.1016/0898-6568(95)02016-0  0.38
1996 Marrero MB, Schieffer B, Ma H, Bernstein KE, Ling BN. ANG II-induced tyrosine phosphorylation stimulates phospholipase C-γ1 and Cl- channels in mesangial cells American Journal of Physiology - Cell Physiology. 270. PMID 8764169 DOI: 10.1152/Ajpcell.1996.270.6.C1834  0.346
1996 Marrero MB, Schieffer B, Bernstein KE, Ling BN. Angiotensin II-induced tyrosine phosphorylation in mesangial and vascular smooth muscle cells Clinical and Experimental Pharmacology and Physiology. 23: 83-88. PMID 8713501 DOI: 10.1111/J.1440-1681.1996.Tb03067.X  0.318
1996 Zhou Y, Overbeek PA, Bernstein KE. Tissue specific expression of testis angiotensin converting enzyme is not determined by the -32 nonconsensus TATA motif Biochemical and Biophysical Research Communications. 223: 48-53. PMID 8660377 DOI: 10.1006/Bbrc.1996.0844  0.434
1996 Esther CR, Howard TE, Marino EM, Goddard JM, Capecchi MR, Bernstein KE. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Laboratory Investigation; a Journal of Technical Methods and Pathology. 74: 953-65. PMID 8642790  0.401
1996 Schieffer B, Paxton WG, Chai Q, Marrero MB, Bernstein KE. Angiotensin II controls p21ras activity via pp60c-src Journal of Biological Chemistry. 271: 10329-10333. PMID 8626602 DOI: 10.1074/Jbc.271.17.10329  0.327
1996 Schieffer B, Paxton WG, Marrero MB, Bernstein KE. Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling Hypertension. 27: 476-480. PMID 8613189 DOI: 10.1161/01.Hyp.27.3.476  0.395
1996 Bernstein KE, Marrero MB. The importance of tyrosine phosphorylation in angiotensin II signaling Trends in Cardiovascular Medicine. 6: 179-187. DOI: 10.1016/S1050-1738(96)00053-9  0.379
1995 Marrero MB, Schieffer B, Paxton WG, Duff JL, Berk BC, Bernstein KE. The role of tyrosine phosphorylation in angiotensin II-mediated intracellular signalling. Cardiovascular Research. 30: 530-6. PMID 8575001 DOI: 10.1016/S0008-6363(95)00094-1  0.361
1995 Duff JL, Marrero MB, Paxton WG, Schieffer B, Bernstein KE, Berk BC. Angiotensin II signal transduction and the mitogen-activated protein kinase pathway. Cardiovascular Research. 30: 511-7. PMID 8574999 DOI: 10.1016/S0008-6363(95)00088-7  0.333
1995 Fishel RS, Eisenberg S, Shai SY, Redden RA, Bernstein KE, Berk BC. Glucocorticoids induce angiotensin-converting enzyme expression in vascular smooth muscle Hypertension. 25: 343-349. PMID 7875759 DOI: 10.1161/01.Hyp.25.3.343  0.416
1995 Fishel RS, Thourani V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells: Possible mediator of the response to vascular injury Journal of Clinical Investigation. 95: 377-387. PMID 7814638 DOI: 10.1172/Jci117666  0.385
1995 Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor Nature. 375: 247-250. PMID 7746328 DOI: 10.1038/375247A0  0.37
1995 Zhou Y, Delafontaine P, Martin BM, Bernstein KE. Identification of two positive transcriptional elements within the 91- base pair promoter for mouse testis angiotensin converting enzyme (testis ACE) Developmental Genetics. 16: 201-209. PMID 7736668 DOI: 10.1002/Dvg.1020160212  0.302
1995 Ishida M, Marrero MB, Schieffer B, Ishida T, Bernstein KE, Berk BC. Angiotensin II activates pp60c-src in vascular smooth muscle cells Circulation Research. 77: 1053-1059. PMID 7586216 DOI: 10.1161/01.Res.77.6.1053  0.37
1995 Marrero MB, Schieffer B, Paxton WG, Schieffer E, Bernstein KE. Electroporation of pp60c-src antibodies inhibits the angiotensin II activation of phospholipase C-γ1 in rat aortic smooth muscle cells Journal of Biological Chemistry. 270: 15734-15738. PMID 7541047 DOI: 10.1074/Jbc.270.26.15734  0.328
1994 Esther CR, Thomas KE, Bernstein KE. Chicken lacks the testis specific isozyme of angiotensin converting enzyme found in mammals. Biochemical and Biophysical Research Communications. 205: 1916-21. PMID 7811282 DOI: 10.1006/Bbrc.1994.2894  0.44
1993 Bihoreau C, Monnot C, Davies E, Teutsch B, Bernstein KE, Corvol P, Clauser E. Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling Proceedings of the National Academy of Sciences of the United States of America. 90: 5133-5137. PMID 8506360 DOI: 10.1073/Pnas.90.11.5133  0.365
1993 Langford KG, Zhou Y, Russell LD, Wilcox JN, Bernstein KE. Regulated expression of testis angiotensin-converting enzyme during spermatogenesis in mice Biology of Reproduction. 48: 1210-1218. PMID 8391328 DOI: 10.1095/Biolreprod48.6.1210  0.44
1993 Bernstein KE, Shai SY, Howard T, Balogh R, Frenzel K, Langford K. Structure and regulated expression of angiotensin-converting enzyme and the receptor for angiotensin II. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 21: 53-7. PMID 8385419 DOI: 10.1016/0272-6386(93)70075-A  0.506
1993 Howard T, Balogh R, Overbeek P, Bernstein KE. Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element. Molecular and Cellular Biology. 13: 18-27. PMID 8380220 DOI: 10.1128/Mcb.13.1.18  0.393
1993 Bernstein KE, Berk BC. The biology of angiotensin II receptors American Journal of Kidney Diseases. 22: 745-754. PMID 8238023 DOI: 10.1016/S0272-6386(12)80441-0  0.373
1993 Paxton WG, Runge M, Horaist C, Cohen C, Alexander RW, Bernstein KE. Immunohistochemical localization of rat angiotensin II AT1 receptor American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 264. PMID 7686719 DOI: 10.1152/Ajprenal.1993.264.6.F989  0.319
1993 Eisenlohr LC, Bacik I, Bennink JR, Bernstein K, Yewdell JW. Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes. Cell. 71: 963-72. PMID 1333889 DOI: 10.1016/0092-8674(92)90392-P  0.338
1992 Bernstein KE, Alexander RW. COUNTERPOINT: Molecular analysis of the angiotensin II receptor Endocrine Reviews. 13: 381-386. PMID 1618167 DOI: 10.1210/Edrv-13-2-381  0.408
1992 Bernstein KE. Molecular analysis of the renin-angiotensin system Seminars in Nephrology. 12: 524-530. PMID 1335611 DOI: 10.5555/Uri:Pii:0270929592900483  0.322
1992 Bernstein KE, Howard TE, Shai SY, Langford KG, Balogh R. Tissue specific expression of angiotensin converting enzyme. Agents and Actions. Supplements. 38: 376-83. PMID 1334622  0.354
1991 Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor Nature. 351: 233-236. PMID 2041570 DOI: 10.1038/351233A0  0.404
1991 Langford KG, Shai SY, Howard TE, Kovac MJ, Overbeek PA, Bernstein KE. Transgenic mice demonstrate a testis-specific promoter for angiotensin- converting enzyme Journal of Biological Chemistry. 266: 15559-15562. PMID 1651914  0.365
1990 Howard TE, Shai SY, Langford KG, Martin BM, Bernstein KE. Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene Molecular and Cellular Biology. 10: 4294-4302. PMID 2164636 DOI: 10.1128/Mcb.10.8.4294  0.388
1990 Shai SY, Langford KG, Martin BM, Bernstein KE. Genomic DNA 5′ to the mouse and human angiotensin-converting enzyme genes contains two distinct regions of conserved sequence Biochemical and Biophysical Research Communications. 167: 1128-1133. PMID 2157425 DOI: 10.1016/0006-291X(90)90640-9  0.303
1990 Bernstein KE, Welsh SL, Inman JK. A deeply recessed active site in angiotensin-converting enzyme is indicated from the binding characteristics of biotin-spacer-inhibitor reagents Biochemical and Biophysical Research Communications. 167: 310-316. PMID 2155615 DOI: 10.1016/0006-291X(90)91766-L  0.393
1990 Shai SY, Fishel RS, Martin BM, Berk BC, Bernstein KE. Bovine angiotensin converting enzyme cDNA cloning and regulation: Increased expression during endothelial cell growth arrest Circulation Research. 70: 1274-1281. PMID 1315639 DOI: 10.1161/01.Res.70.6.1274  0.452
1988 Bernstein KE, Martin BM, Bernstein EA, Linton J, Striker L, Striker G. The isolation of angiotensin-converting enzyme cDNA Journal of Biological Chemistry. 263: 11021-11024. PMID 2841312  0.334
1988 Bernstein KE, Martin BM, Striker L, Striker G. Partial protein sequence of mouse and bovine kidney angiotensin converting enzyme Kidney International. 33: 652-655. PMID 2835538  0.341
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