Jeffrey S. Schorey - Publications

Affiliations: 
University of Notre Dame, Notre Dame, IN, United States 
Area:
Cell Biology, Microbiology Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cheng Y, Kiene NJ, Tatarian A, Eix EF, Schorey JS. Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages. Plos Pathogens. 16: e1008569. PMID 32463840 DOI: 10.1371/Journal.Ppat.1008569  0.517
2019 Cheng Y, Schorey JS. Extracellular vesicles deliver RNA to promote host immunity and bacterial killing. Embo Reports. PMID 30683680 DOI: 10.15252/embr.201846613  0.423
2018 Cheng Y, Schorey JS. -induced IFN-β production requires cytosolic DNA and RNA sensing pathways. The Journal of Experimental Medicine. PMID 30337468 DOI: 10.1084/Jem.20180508  0.382
2018 Li L, Cheng Y, Emrich S, Schorey J. Activation of endothelial cells by extracellular vesicles derived from Mycobacterium tuberculosis infected macrophages or mice. Plos One. 13: e0198337. PMID 29851993 DOI: 10.1371/Journal.Pone.0198337  0.503
2018 D'Souza-Schorey C, Schorey JS. Regulation and mechanisms of extracellular vesicle biogenesis and secretion. Essays in Biochemistry. PMID 29666210 DOI: 10.1042/Ebc20170078  0.32
2017 Sigal GB, Segal MR, Mathew A, Jarlsberg L, Wang M, Barbero S, Small N, Haynesworth K, Davis JL, Weiner M, Whitworth WC, Jacobs J, Schorey J, Lewinsohn DM, Nahid P. Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial. Ebiomedicine. PMID 29100778 DOI: 10.1016/J.Ebiom.2017.10.018  0.322
2017 Cheng Y, Liepert LD, Waller J, Leevy WM, Schorey JS. A novel method for intratracheal injection of infectious agents into mice. Laboratory Animals. 51: 530-533. PMID 28948897 DOI: 10.1177/0023677216684422  0.313
2017 Cheng Y, Schorey JS, Zhang CC, Tan X. Protein Kinase Inhibitors as Potential Antimicrobial Drugs against Tuberculosis, Malaria and HIV. Current Pharmaceutical Design. PMID 28606053 DOI: 10.2174/1381612823666170612122429  0.346
2017 Smith VL, Cheng Y, Bryant BR, Schorey JS. Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection. Scientific Reports. 7: 43578. PMID 28262829 DOI: 10.1038/Srep43578  0.501
2016 Schorey JS, Schlesinger LS. Innate Immune Responses to Tuberculosis. Microbiology Spectrum. 4. PMID 28087945 DOI: 10.1128/Microbiolspec.Tbtb2-0010-2016  0.513
2016 Moraski GC, Cheng Y, Cho S, Cramer JW, Godfrey A, Masquelin T, Franzblau SG, Miller MJ, Schorey J. Imidazo[1,2-a]pyridine-3-carboxamides are Active Antimicrobial Agents of Mycobacterium avium Infection In Vivo. Antimicrobial Agents and Chemotherapy. PMID 27216051 DOI: 10.1128/Aac.00618-16  0.374
2016 Schorey JS, Harding CV. Extracellular vesicles and infectious diseases: new complexity to an old story. The Journal of Clinical Investigation. 126: 1181-9. PMID 27035809 DOI: 10.1172/Jci81132  0.448
2015 Smith VL, Jackson L, Schorey JS. Ubiquitination as a Mechanism To Transport Soluble Mycobacterial and Eukaryotic Proteins to Exosomes. Journal of Immunology (Baltimore, Md. : 1950). 195: 2722-30. PMID 26246139 DOI: 10.4049/Jimmunol.1403186  0.376
2015 Singh PP, Li L, Schorey JS. Exosomal RNA from Mycobacterium tuberculosis-Infected Cells Is Functional in Recipient Macrophages. Traffic (Copenhagen, Denmark). 16: 555-71. PMID 25753779 DOI: 10.1111/Tra.12278  0.501
2015 Schorey JS, Cheng Y, Singh PP, Smith VL. Exosomes and other extracellular vesicles in host-pathogen interactions. Embo Reports. 16: 24-43. PMID 25488940 DOI: 10.15252/Embr.201439363  0.455
2014 Kruh-Garcia NA, Wolfe LM, Chaisson LH, Worodria WO, Nahid P, Schorey JS, Davis JL, Dobos KM. Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS. Plos One. 9: e103811. PMID 25080351 DOI: 10.1371/Journal.Pone.0103811  0.394
2014 Cheng Y, Moraski GC, Cramer J, Miller MJ, Schorey JS. Bactericidal activity of an imidazo[1, 2-a]pyridine using a mouse M. tuberculosis infection model. Plos One. 9: e87483. PMID 24498115 DOI: 10.1371/Journal.Pone.0087483  0.411
2014 Kruh-Garcia NA, Wolfe LM, Chaisson LH, Worodria WO, Nahid P, Schorey JS, Davis JL, Dobos KM. Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS Plos One. 9. DOI: 10.1371/journal.pone.0103811  0.312
2013 Cheng Y, Schorey JS. Exosomes carrying mycobacterial antigens can protect mice against Mycobacterium tuberculosis infection. European Journal of Immunology. 43: 3279-90. PMID 23943377 DOI: 10.1002/eji.201343727  0.363
2013 Ricardo-Carter C, Favila M, Polando RE, Cotton RN, Bogard Horner K, Condon D, Ballhorn W, Whitcomb JP, Yadav M, Geister RL, Schorey JS, McDowell MA. Leishmania major inhibits IL-12 in macrophages by signalling through CR3 (CD11b/CD18) and down-regulation of ETS-mediated transcription. Parasite Immunology. 35: 409-20. PMID 23834512 DOI: 10.1111/Pim.12049  0.599
2012 Singh PP, Smith VL, Karakousis PC, Schorey JS. Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 189: 777-85. PMID 22723519 DOI: 10.4049/jimmunol.1103638  0.527
2011 Singh PP, LeMaire C, Tan JC, Zeng E, Schorey JS. Exosomes released from M. tuberculosis infected cells can suppress IFN-γ mediated activation of naïve macrophages. Plos One. 6: e18564. PMID 21533172 DOI: 10.1371/Journal.Pone.0018564  0.494
2010 Giri PK, Kruh NA, Dobos KM, Schorey JS. Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Proteomics. 10: 3190-202. PMID 20662102 DOI: 10.1002/Pmic.200900840  0.525
2010 Sweet L, Singh PP, Azad AK, Rajaram MV, Schlesinger LS, Schorey JS. Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids. Infection and Immunity. 78: 518-26. PMID 19841083 DOI: 10.1128/Iai.00257-09  0.775
2009 Muralidharan-Chari V, Hoover H, Clancy J, Schweitzer J, Suckow MA, Schroeder V, Castellino FJ, Schorey JS, D'Souza-Schorey C. ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo. Cancer Research. 69: 2201-9. PMID 19276388 DOI: 10.1158/0008-5472.Can-08-1301  0.315
2008 Sweet L, Zhang W, Torres-Fewell H, Serianni A, Boggess W, Schorey J. Mycobacterium avium glycopeptidolipids require specific acetylation and methylation patterns for signaling through toll-like receptor 2. The Journal of Biological Chemistry. 283: 33221-31. PMID 18824550 DOI: 10.1074/Jbc.M805539200  0.77
2008 Schorey JS, Sweet L. The mycobacterial glycopeptidolipids: structure, function, and their role in pathogenesis. Glycobiology. 18: 832-41. PMID 18723691 DOI: 10.1093/Glycob/Cwn076  0.789
2008 Giri PK, Schorey JS. Exosomes derived from M. Bovis BCG infected macrophages activate antigen-specific CD4+ and CD8+ T cells in vitro and in vivo. Plos One. 3: e2461. PMID 18560543 DOI: 10.1371/Journal.Pone.0002461  0.492
2008 Schorey JS, Bhatnagar S. Exosome function: from tumor immunology to pathogen biology. Traffic (Copenhagen, Denmark). 9: 871-81. PMID 18331451 DOI: 10.1111/J.1600-0854.2008.00734.X  0.598
2008 Schorey JS, Lawrence C. The pattern recognition receptor dectin-1: From fungi to mycobacteria Current Drug Targets. 9: 123-129. PMID 18288963 DOI: 10.2174/138945008783502430  0.375
2007 Bhatnagar S, Shinagawa K, Castellino FJ, Schorey JS. Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo. Blood. 110: 3234-44. PMID 17666571 DOI: 10.1182/Blood-2007-03-079152  0.748
2007 Bhatnagar S, Schorey JS. Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory. The Journal of Biological Chemistry. 282: 25779-89. PMID 17591775 DOI: 10.1074/Jbc.M702277200  0.737
2006 Yadav M, Schorey JS. The beta-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria. Blood. 108: 3168-75. PMID 16825490 DOI: 10.1182/Blood-2006-05-024406  0.743
2006 Sweet L, Schorey JS. Glycopeptidolipids from Mycobacterium avium promote macrophage activation in a TLR2- and MyD88-dependent manner. Journal of Leukocyte Biology. 80: 415-23. PMID 16760377 DOI: 10.1189/Jlb.1205702  0.826
2006 Yadav M, Clark L, Schorey JS. Macrophage's proinflammatory response to a mycobacterial infection is dependent on sphingosine kinase-mediated activation of phosphatidylinositol phospholipase C, protein kinase C, ERK1/2, and phosphatidylinositol 3-kinase. Journal of Immunology (Baltimore, Md. : 1950). 176: 5494-503. PMID 16622018 DOI: 10.4049/Jimmunol.176.9.5494  0.732
2006 Bhatnagar S, Schorey JS. Elevated mitogen-activated protein kinase signalling and increased macrophage activation in cells infected with a glycopeptidolipid-deficient Mycobacterium avium. Cellular Microbiology. 8: 85-96. PMID 16367868 DOI: 10.1111/J.1462-5822.2005.00602.X  0.761
2006 Schorey J. Macrophage activation:'tis the way the WNT blows Blood. 108: 784-784. DOI: 10.1182/Blood-2006-05-022392  0.468
2005 Lee SB, Schorey JS. Activation and mitogen-activated protein kinase regulation of transcription factors Ets and NF-kappaB in Mycobacterium-infected macrophages and role of these factors in tumor necrosis factor alpha and nitric oxide synthase 2 promoter function. Infection and Immunity. 73: 6499-507. PMID 16177323 DOI: 10.1128/Iai.73.10.6499-6507.2005  0.518
2005 Krzywinska E, Bhatnagar S, Sweet L, Chatterjee D, Schorey JS. Mycobacterium avium 104 deleted of the methyltransferase D gene by allelic replacement lacks serotype-specific glycopeptidolipids and shows attenuated virulence in mice. Molecular Microbiology. 56: 1262-73. PMID 15882419 DOI: 10.1111/J.1365-2958.2005.04608.X  0.791
2005 Roach SK, Lee SB, Schorey JS. Differential activation of the transcription factor cyclic AMP response element binding protein (CREB) in macrophages following infection with pathogenic and nonpathogenic mycobacteria and role for CREB in tumor necrosis factor alpha production. Infection and Immunity. 73: 514-22. PMID 15618191 DOI: 10.1128/Iai.73.1.514-522.2005  0.805
2004 Kelley VA, Schorey JS. Modulation of cellular phosphatidylinositol 3-phosphate levels in primary macrophages affects heat-killed but not viable Mycobacterium avium's transport through the phagosome maturation process. Cellular Microbiology. 6: 973-85. PMID 15339272 DOI: 10.1111/J.1462-5822.2004.00415.X  0.772
2004 Krzywinska E, Krzywinski J, Schorey JS. Naturally occurring horizontal gene transfer and homologous recombination in Mycobacterium. Microbiology (Reading, England). 150: 1707-12. PMID 15184557 DOI: 10.1099/Mic.0.27088-0  0.337
2004 Krzywinska E, Krzywinski J, Schorey JS. Phylogeny of Mycobacterium avium strains inferred from glycopeptidolipid biosynthesis pathway genes. Microbiology (Reading, England). 150: 1699-706. PMID 15184556 DOI: 10.1099/Mic.0.27007-0  0.361
2004 Yadav M, Roach SK, Schorey JS. Increased mitogen-activated protein kinase activity and TNF-alpha production associated with Mycobacterium smegmatis- but not Mycobacterium avium-infected macrophages requires prolonged stimulation of the calmodulin/calmodulin kinase and cyclic AMP/protein kinase A pathways. Journal of Immunology (Baltimore, Md. : 1950). 172: 5588-97. PMID 15100302 DOI: 10.4049/Jimmunol.172.9.5588  0.79
2003 Kelley VA, Schorey JS. Mycobacterium's arrest of phagosome maturation in macrophages requires Rab5 activity and accessibility to iron. Molecular Biology of the Cell. 14: 3366-77. PMID 12925769 DOI: 10.1091/Mbc.E02-12-0780  0.781
2003 Sato J, Schorey J, Ploplis VA, Haalboom E, Krahule L, Castellino FJ. The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection. The American Journal of Pathology. 163: 517-31. PMID 12875972 DOI: 10.1016/S0002-9440(10)63680-2  0.495
2003 Schorey JS, Cooper AM. Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way. Cellular Microbiology. 5: 133-42. PMID 12614457 DOI: 10.1046/J.1462-5822.2003.00263.X  0.58
2003 Krzywinska E, Schorey JS. Characterization of genetic differences between Mycobacterium avium subsp. avium strains of diverse virulence with a focus on the glycopeptidolipid biosynthesis cluster. Veterinary Microbiology. 91: 249-64. PMID 12458173 DOI: 10.1016/S0378-1135(02)00292-4  0.333
2002 Roach SK, Schorey JS. Differential regulation of the mitogen-activated protein kinases by pathogenic and nonpathogenic mycobacteria. Infection and Immunity. 70: 3040-52. PMID 12010996 DOI: 10.1128/Iai.70.6.3040-3052.2002  0.813
2001 Bohlson SS, Strasser JA, Bower JJ, Schorey JS. Role of complement in Mycobacterium avium pathogenesis: in vivo and in vitro analyses of the host response to infection in the absence of complement component C3. Infection and Immunity. 69: 7729-35. PMID 11705954 DOI: 10.1128/Iai.69.12.7729-7735.2001  0.788
2000 Zhao W, Schorey JS, Bong-Mastek M, Ritchey J, Brown EJ, Ratliff TL. Role of a bacillus calmette-guerin fibronectin attachment protein in BCG-induced antitumor activity International Journal of Cancer. 86: 83-88. PMID 10728599 DOI: 10.1002/(Sici)1097-0215(20000401)86:1<83::Aid-Ijc13>3.0.Co;2-R  0.304
1998 Holsti MA, Schorey JS, Brown EJ, Allen PM. Identification of epitopes of fibronectin attachment protein (FAP-A) of Mycobacterium avium which stimulate strong T-cell responses in mice Infection and Immunity. 66: 1261-1264. PMID 9488424 DOI: 10.1128/Iai.66.3.1261-1264.1998  0.342
1997 Schorey JS, Carroll MC, Brown EJ. A macrophage invasion mechanism of pathogenic mycobacteria Science. 277: 1091-1093. PMID 9262476 DOI: 10.1126/science.277.5329.1091  0.435
1996 Schorey JS, Holsti MA, Ratliff TL, Allen PM, Brown EJ. Characterization of the fibronectin-attachment protein of Mycobacterium avium reveals a fibronectin-binding motif conserved among mycobacteria Molecular Microbiology. 21: 321-329. PMID 8858587 DOI: 10.1046/J.1365-2958.1996.6381353.X  0.352
1995 Schorey JS, Li Q, McCourt DW, Bong-Mastek M, Clark-Curtiss JE, Ratliff TL, Brown EJ. A Mycobacterium leprae gene encoding a fibronectin binding protein is used for efficient invasion of epithelial cells and Schwann cells Infection and Immunity. 63: 2652-2657. PMID 7790081 DOI: 10.1128/Iai.63.7.2652-2657.1995  0.389
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