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Liang Shan, Ph.D. - Publications

Affiliations: 
2012 Johns Hopkins University, Baltimore, MD 
Area:
Virology Biology, Immunology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang Q, Clark KM, Tiwari R, Raju N, Tharp GK, Rogers J, Harris RA, Raveendran M, Bosinger SE, Burdo TH, Silvestri G, Shan L. The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression. Cell. 187: 1223-1237.e16. PMID 38428396 DOI: 10.1016/j.cell.2024.01.048  0.584
2023 Pinzone MR, Shan L. Pharmacological approaches to promote cell death of latent HIV reservoirs. Current Opinion in Hiv and Aids. 19: 56-61. PMID 38169429 DOI: 10.1097/COH.0000000000000837  0.527
2023 Psaros C, Goodman GR, McDonald VW, Ott C, Blyler A, Rivas A, Shan L, Campbell M, Underwood E, Krakower D, Elopre L, Kudroff K, Sherr KH, Kempf MC. Protocol for WeExPAnd: a prospective, mixed-methods pilot demonstration study to increase access to pre-exposure prophylaxis among women vulnerable to HIV infection in the Southern USA. Bmj Open. 13: e075250. PMID 37286316 DOI: 10.1136/bmjopen-2023-075250  0.438
2023 Clark KM, Wang Q, Shan L. CARD8 Inflammasome Activation by HIV-1 Protease. Methods in Molecular Biology (Clifton, N.J.). 2641: 67-79. PMID 37074642 DOI: 10.1007/978-1-0716-3040-2_6  0.534
2023 Clark KM, Pal P, Kim JG, Wang Q, Shan L. The CARD8 inflammasome in HIV infection. Advances in Immunology. 157: 59-100. PMID 37061288 DOI: 10.1016/bs.ai.2022.11.001  0.613
2023 Li Y, Gao H, Clark KM, Shan L. IL15 enhances HIV-1 infection by promoting survival and proliferation of CCR5+CD4+ T cells. Jci Insight. PMID 36821374 DOI: 10.1172/jci.insight.166292  0.498
2022 Wang Q, Shan L. Inflammasomes in Human Immunodeficiency Virus Type 1 Infection. Infectious Diseases & Immunity. 2: 248-252. PMID 36798147 DOI: 10.1097/ID9.0000000000000070  0.512
2022 Clark KM, Kim JG, Wang Q, Gao H, Presti RM, Shan L. Chemical inhibition of DPP9 sensitizes the CARD8 inflammasome in HIV-1-infected cells. Nature Chemical Biology. PMID 36357533 DOI: 10.1038/s41589-022-01182-5  0.619
2022 Sungur CM, Wang Q, Ozantürk AN, Gao H, Schmitz AJ, Cella M, Yokoyama WM, Shan L. Human natural killer cells confer protection against HIV-1 infection in humanized mice. The Journal of Clinical Investigation. PMID 36282589 DOI: 10.1172/JCI162694  0.507
2022 Kim JG, Shan L. Beyond Inhibition: A Novel Strategy of Targeting HIV-1 Protease to Eliminate Viral Reservoirs. Viruses. 14. PMID 35746649 DOI: 10.3390/v14061179  0.562
2021 Rajashekar JK, Richard J, Beloor J, Prévost J, Anand SP, Beaudoin-Bussières G, Shan L, Herndler-Brandstetter D, Gendron-Lepage G, Medjahed H, Bourassa C, Gaudette F, Ullah I, Symmes K, Peric A, et al. Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir. Cell Host & Microbe. PMID 34019804 DOI: 10.1016/j.chom.2021.04.014  0.579
2021 Gao H, Ozantürk AN, Wang Q, Harlan GH, Schmitz AJ, Presti RM, Deng K, Shan L. Evaluation of HIV-1 latency reversal and antibody-dependent viral clearance by quantification of singly spliced HIV-1 / mRNA. Journal of Virology. PMID 33762408 DOI: 10.1128/JVI.02124-20  0.57
2021 Wang Q, Gao H, Clark KM, Mugisha CS, Davis K, Tang JP, Harlan GH, DeSelm CJ, Presti RM, Kutluay SB, Shan L. CARD8 is an inflammasome sensor for HIV-1 protease activity. Science (New York, N.Y.). PMID 33542150 DOI: 10.1126/science.abe1707  0.59
2019 Cella M, Gamini R, Sécca C, Collins PL, Zhao S, Peng V, Robinette ML, Schettini J, Zaitsev K, Gordon W, Bando JK, Yomogida K, Cortez V, Fronick C, Fulton R, ... ... Shan L, et al. Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues. Nature Immunology. PMID 31209406 DOI: 10.1038/S41590-019-0425-Y  0.32
2017 Ring NG, Herndler-Brandstetter D, Weiskopf K, Shan L, Volkmer JP, George BM, Lietzenmayer M, McKenna KM, Naik TJ, McCarty A, Zheng Y, Ring AM, Flavell RA, Weissman IL. Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158380 DOI: 10.1073/Pnas.1710877114  0.322
2017 Herndler-Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, Strowig T, de Zoete MR, Palm NW, Chen J, Blish CA, Frleta D, Gurer C, Macdonald LE, Murphy AJ, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078283 DOI: 10.1073/Pnas.1705301114  0.342
2017 Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, et al. Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4(+) T Cells Permissive for Latent HIV-1 Infection. Immunity. 47: 766-775.e3. PMID 29045905 DOI: 10.1016/J.Immuni.2017.09.014  0.807
2017 Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, ... ... Shan L, et al. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. PMID 28636595 DOI: 10.1038/Nature22967  0.338
2015 Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, ... ... Shan L, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 517: 381-5. PMID 25561180 DOI: 10.1038/Nature14053  0.77
2014 Shan L, Siliciano RF. Unraveling the relationship between microbial translocation and systemic immune activation in HIV infection. The Journal of Clinical Investigation. 124: 2368-71. PMID 24837427 DOI: 10.1172/Jci75799  0.679
2014 Chiu YL, Shan L, Huang H, Haupt C, Bessell C, Canaday DH, Zhang H, Ho YC, Powell JD, Oelke M, Margolick JB, Blankson JN, Griffin DE, Schneck JP. Sprouty-2 regulates HIV-specific T cell polyfunctionality. The Journal of Clinical Investigation. 124: 198-208. PMID 24292711 DOI: 10.1172/Jci70510  0.557
2014 Shan L, Xing S, Yang HC, Zhang H, Margolick JB, Siliciano RF. Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells. The Journal of Antimicrobial Chemotherapy. 69: 28-33. PMID 23999005 DOI: 10.1093/Jac/Dkt338  0.812
2014 Shan L. Update on HIV reservoirs Bmc Infectious Diseases. 14. DOI: 10.1186/1471-2334-14-S2-S18  0.493
2014 Chiu YL, Shan L, Huang H, Haupt C, Bessell C, Canaday DH, Zhang H, Ho YC, Powell JD, Oelke M, Margolick JB, Blankson JN, Griffin DE, Schneck JP. Sprouty-2 regulates HIV-specific T cell polyfunctionality Journal of Clinical Investigation. 124: 198-208. DOI: 10.1172/JCI70510  0.549
2013 Ho YC, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DI, Lai J, Blankson JN, Siliciano JD, Siliciano RF. Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell. 155: 540-51. PMID 24243014 DOI: 10.1016/J.Cell.2013.09.020  0.692
2013 Rabi SA, Laird GM, Durand CM, Laskey S, Shan L, Bailey JR, Chioma S, Moore RD, Siliciano RF. Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance. The Journal of Clinical Investigation. 123: 3848-60. PMID 23979165 DOI: 10.1172/Jci67399  0.684
2013 Sherrill-Mix S, Lewinski MK, Famiglietti M, Bosque A, Malani N, Ocwieja KE, Berry CC, Looney D, Shan L, Agosto LM, Pace MJ, Siliciano RF, O'Doherty U, Guatelli J, Planelles V, et al. HIV latency and integration site placement in five cell-based models. Retrovirology. 10: 90. PMID 23953889 DOI: 10.1186/1742-4690-10-90  0.672
2013 Shan L, Siliciano RF. From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 544-52. PMID 23613347 DOI: 10.1002/Bies.201200170  0.743
2013 Shan L, Rabi SA, Laird GM, Eisele EE, Zhang H, Margolick JB, Siliciano RF. A novel PCR assay for quantification of HIV-1 RNA. Journal of Virology. 87: 6521-5. PMID 23536672 DOI: 10.1128/Jvi.00006-13  0.699
2012 Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, Zhang H, Margolick JB, Blankson JN, Siliciano RF. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity. 36: 491-501. PMID 22406268 DOI: 10.1016/J.Immuni.2012.01.014  0.81
2012 Durand CM, Ghiaur G, Siliciano JD, Rabi SA, Eisele EE, Salgado M, Shan L, Lai JF, Zhang H, Margolick J, Jones RJ, Gallant JE, Ambinder RF, Siliciano RF. HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy. The Journal of Infectious Diseases. 205: 1014-8. PMID 22275402 DOI: 10.1093/Infdis/Jir884  0.753
2011 Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs. Science Translational Medicine. 3: 91ra63. PMID 21753122 DOI: 10.1126/Scitranslmed.3002304  0.74
2011 Xing S, Bullen CK, Shroff NS, Shan L, Yang HC, Manucci JL, Bhat S, Zhang H, Margolick JB, Quinn TC, Margolis DM, Siliciano JD, Siliciano RF. Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. Journal of Virology. 85: 6060-4. PMID 21471244 DOI: 10.1128/Jvi.02033-10  0.821
2011 Shan L, Yang HC, Rabi SA, Bravo HC, Shroff NS, Irizarry RA, Zhang H, Margolick JB, Siliciano JD, Siliciano RF. Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model. Journal of Virology. 85: 5384-93. PMID 21430059 DOI: 10.1128/Jvi.02536-10  0.804
2011 Spivak AM, Rabi SA, McMahon MA, Shan L, Sedaghat AR, Wilke CO, Siliciano RF. Short communication: dynamic constraints on the second phase compartment of HIV-infected cells. Aids Research and Human Retroviruses. 27: 759-61. PMID 21105850 DOI: 10.1089/Aid.2010.0199  0.783
2009 Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. The Journal of Clinical Investigation. 119: 3473-86. PMID 19805909 DOI: 10.1172/Jci39199  0.725
2009 Zhu J, Liao G, Shan L, Zhang J, Chen MR, Hayward GS, Hayward SD, Desai P, Zhu H. Protein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4. Journal of Virology. 83: 5219-31. PMID 19244323 DOI: 10.1128/Jvi.02378-08  0.308
2008 Wang L, Shan L, Lo KW, Yin J, Zhang Y, Sun R, Zhong J. Inhibition of nasopharyngeal carcinoma growth by RTA-expressing baculovirus vectors containing oriP. The Journal of Gene Medicine. 10: 1124-33. PMID 18642396 DOI: 10.1002/Jgm.1237  0.346
2006 Shan L, Wang L, Yin J, Zhong P, Zhong J. An OriP/EBNA-1-based baculovirus vector with prolonged and enhanced transgene expression. The Journal of Gene Medicine. 8: 1400-6. PMID 17051599 DOI: 10.1002/Jgm.978  0.341
2006 Wang L, Shan L, Yin J, Zhao M, Su D, Zhong J. The activation of lytic replication of Epstein-Barr virus by baculovirus-mediated gene transduction. Archives of Virology. 151: 2047-53. PMID 16673043 DOI: 10.1007/S00705-006-0772-5  0.413
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