Amrita D. Joshi, Ph.D. - Publications

Affiliations: 
2000 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, et al. Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair. Cellular & Molecular Immunology. PMID 36127466 DOI: 10.1038/s41423-022-00919-5  0.421
2022 Wolf SJ, Audu CO, Joshi A, denDekker AD, Melvin WJ, Davis FM, Xing X, Wasikowski R, Tsoi L, Kunkel S, Gudjonsson JE, O'Riordan MX, Kahlenberg JM, Gallagher KA. Interferon kappa (IFNk) is critical for normal wound repair and is decreased in diabetic wounds. Jci Insight. PMID 35358091 DOI: 10.1172/jci.insight.152765  0.335
2021 Melvin WJ, Audu CO, Davis FM, Sharma SB, Joshi A, DenDekker A, Wolf S, Barrett E, Mangum K, Zhou X, Bame M, Ruan A, Obi A, Kunkel SL, Moore BB, et al. Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34479991 DOI: 10.1073/pnas.2101071118  0.361
2020 Davis FM, Tsoi LC, Wasikowski R, denDekker A, Joshi A, Wilke C, Deng H, Wolf S, Obi A, Huang S, Billi AC, Robinson S, Lipinski J, Melvin WJ, Audu CO, et al. Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair. Jci Insight. 5. PMID 32879137 DOI: 10.1172/Jci.Insight.138443  0.516
2020 Davis FM, denDekker A, Joshi AD, Wolf SJ, Audu C, Melvin WJ, Mangum K, Riordan MO, Kunkel SL, Gallagher KA. Palmitate-TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing. European Journal of Immunology. PMID 32662520 DOI: 10.1002/Eji.202048651  0.512
2020 Davis FM, denDekker A, Kimball A, Joshi AD, El Azzouny M, Wolf SJ, Obi AT, Lipinski J, Gudjonsson JE, Xing X, Plazyo O, Audu C, Melvin WJ, Singer K, Henke PK, et al. Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair. Journal of Immunology (Baltimore, Md. : 1950). PMID 32205424 DOI: 10.4049/Jimmunol.1901263  0.505
2020 denDekker AD, Davis FM, Joshi AD, Wolf SJ, Allen R, Lipinski J, Nguyen B, Kirma J, Nycz D, Bermick JR, Moore BB, Gudjonsson JE, Kunkel SL, Gallagher KA. TNFα regulates diabetic macrophage function through the histone acetyl-transferase, MOF. Jci Insight. PMID 32069267 DOI: 10.1172/Jci.Insight.132306  0.503
2020 Davis FM, Dendekker A, Joshi A, Wolf S, Moore B, Lukacs N, Gallagher K. Epigenetic Regulation of Toll-like Receptor 4 Signaling Modulates Macrophage Phenotype and Impairs Diabetic Wound Healing Journal of Vascular Surgery. 72. DOI: 10.1016/J.Jvs.2020.04.431  0.456
2020 Davis FM, denDekker A, Joshi AD, Wolf SJ, Audu C, Melvin WJ, Mangum K, Riordan MO, Kunkel SL, Gallagher KA. Author response for "Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing" European Journal of Immunology. DOI: 10.1002/Eji.202048651/V2/Response1  0.447
2019 Davis FM, Schaller MA, Dendekker A, Joshi AD, Kimball AS, Evanoff H, Wilke C, Obi AT, Melvin WJ, Cavassani K, Scola M, Carson B, Moser S, Blanc V, Engoren M, et al. Sepsis Induces Prolonged Epigenetic Modifications in Bone Marrow and Peripheral Macrophages Impairing Inflammation and Wound Healing. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 2353-2366. PMID 31644352 DOI: 10.1161/Atvbaha.119.312754  0.432
2019 Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, et al. The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. Immunity. PMID 31350176 DOI: 10.1016/J.Immuni.2019.06.015  0.514
2019 Boniakowski AE, denDekker AD, Davis FM, Joshi A, Kimball AS, Schaller M, Allen R, Bermick J, Nycz D, Skinner ME, Robinson S, Obi AT, Moore BB, Gudjonsson JE, Lombard D, et al. SIRT3 Regulates Macrophage-Mediated Inflammation in Diabetic Wound Repair. The Journal of Investigative Dermatology. PMID 31207226 DOI: 10.1016/J.Jid.2019.05.017  0.496
2019 Davis FM, Kimball A, denDekker A, Joshi AD, Boniakowski AE, Nysz D, Allen RM, Obi A, Singer K, Henke PK, Moore BB, Kunkel SL, Gallagher KA. Histone Methylation Directs Myeloid TLR4 Expression and Regulates Wound Healing following Cutaneous Tissue Injury. Journal of Immunology (Baltimore, Md. : 1950). PMID 30710046 DOI: 10.4049/Jimmunol.1801258  0.449
2019 DAVIS FM, DENDEKKER AD, KIMBALL AS, BONIAKOWSKI A, JOSHI A, ELAZZOUNY M, BURANT C, GALLAGHER K. 96-OR: Epigenetic Regulation of the TLR4 Pathway in Macrophages via S-adenosyl Methionine Results in Impaired Wound Healing in Diabetes Diabetes. 68: 96-OR. DOI: 10.2337/Db19-96-Or  0.494
2019 Davis FM, denDekker A, Kimball A, Joshi A, Boniakowski A, Kunkel S, Gallagher K. Palmitate-TLR4 Signaling Regulates Epigenetic Modifications in Macrophages and Impairs Diabetic Wound Healing Journal of Vascular Surgery. 70: e58-e59. DOI: 10.1016/J.Jvs.2019.06.132  0.472
2018 Boniakowski AE, Kimball AS, Joshi A, Schaller M, Davis FM, denDekker A, Obi AT, Moore BB, Kunkel SL, Gallagher KA. Murine macrophage chemokine receptor CCR2 plays a crucial role in macrophage recruitment and regulated inflammation in wound healing. European Journal of Immunology. PMID 29879295 DOI: 10.1002/Eji.201747400  0.452
2018 Kimball A, Schaller M, Joshi A, Davis F, denDekker A, Boniakowski A, Bermick J, Obi A, Moore B, Henke PK, Kunkel SL, Gallagher KA. Ly6CBlood Monocyte/Macrophage Drive Chronic Inflammation and Impair Wound Healing in Diabetes Mellitus. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29496661 DOI: 10.1161/Atvbaha.118.310703  0.474
2018 Davis FM, Kimball A, Joshi A, Boniakowski A, Schaller M, DenDekker A, Kunkell S, Moore B, Gallagher K. Abstract 258: Palmitate Regulates Diabetic Macrophage Inflammation via the Epigenetic Enzyme JMJD3 Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.258  0.433
2018 Boniakowski A, Kimball A, Davis F, Joshi A, Schaller M, denDekker A, Kunkel S, Gallagher K. Abstract 255: Fatty Acid Binding Protein 4, FABP4, Causes Impaired Wound Healing in Diabetes Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.255  0.341
2018 Boniakowski A, Kimball A, Davis F, Joshi A, Schaller M, denDekker A, Kunkel S, Gallagher K. PC226. Metabolites Altered in Diabetic Macrophages Influence Chronic Inflammation Journal of Vascular Surgery. 67. DOI: 10.1016/J.Jvs.2018.03.357  0.416
2018 Davis FM, Joshi A, Kimball A, Schaller M, denDekker A, Moore B, Gallagher K. PC220. Impaired Wound Healing in Diabetes Is Driven by Epigenetic Regulation of the Cyclo-Oxygenase-2/PGE2 Pathway in Macrophages Journal of Vascular Surgery. 67: e233. DOI: 10.1016/J.Jvs.2018.03.354  0.472
2018 Davis FM, Joshi A, Kimball AS, denDekker A, Gallagher K. Epigenetic Regulation of Prostaglandin E2 Synthesis Alters Macrophage Function to Promote Inflammation and Impair Diabetic Wound Healing Journal of the American College of Surgeons. 227: S287. DOI: 10.1016/J.Jamcollsurg.2018.07.593  0.455
2017 Carson WF, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL. The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 28733487 DOI: 10.4049/Jimmunol.1601272  0.437
2017 Kimball A, Joshi A, Carson WF, Boniakowski A, Davis F, Schaller M, Allen R, Bermick J, Henke PK, Burant CF, Kunkel SL, Gallagher KA. The Histone Methyltransferase, MLL1, Directs Macrophage-Mediated Inflammation in Wound Healing and is Altered in a Murine Model of Obesity and Type 2 Diabetes. Diabetes. PMID 28663191 DOI: 10.2337/Db17-0194  0.495
2017 Kimball AS, Joshi AD, Boniakowski AE, Schaller M, Chung J, Allen R, Bermick J, Carson WF, Henke PK, Maillard I, Kunkel SL, Gallagher KA. Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing. Frontiers in Immunology. 8: 635. PMID 28620387 DOI: 10.3389/Fimmu.2017.00635  0.498
2017 Carson WF, Salter-Green SE, Scola MM, Joshi A, Gallagher KA, Kunkel SL. Enhancement of macrophage inflammatory responses by CCL2 is correlated with increased miR-9 expression and downregulation of the ERK1/2 phosphatase Dusp6. Cellular Immunology. PMID 28242024 DOI: 10.1016/J.Cellimm.2017.02.005  0.393
2017 Boniakowski AE, Kimball A, Joshi A, Kunkel S, Gallagher K. PC200 A Deacetylase Enzyme, Sirtuin 3, Plays a Major Role in Macrophage Inflammation and Wound Healing Journal of Vascular Surgery. 65: 193S-194S. DOI: 10.1016/J.Jvs.2017.03.365  0.402
2017 Kimball A, Schaller M, Joshi A, Allen R, Bonikowski A, Henke PK, Kunkel S, Gallagher K. Ly6C Hi Inflammatory Monocytes Drive Persistent Inflammation in a Murine Model of Diabetic Wound Healing Journal of the American College of Surgeons. 225: S218. DOI: 10.1016/J.Jamcollsurg.2017.07.503  0.453
2017 Eliassen A, Kimball A, Joshi A, Kunkel S, Gallagher K. A Fatty Acid Binding Protein, FABP4, Alters a Metabolic Enzyme that Plays a Major Role in Macrophage Inflammation, and Wound Healing Journal of the American College of Surgeons. 225: S212. DOI: 10.1016/J.Jamcollsurg.2017.07.488  0.371
2016 Kimball A, Joshi A, Schaller M, Carson WF, Ramani S, Henke P, Kunkel S, Gallagher K. PC238. Epigenetically Altered Toll-Like Receptor 4 Expression May Contribute to Increased Inflammation and Delayed Wound Healing in a Murine Model of Diabetes Journal of Vascular Surgery. 63: 225S-226S. DOI: 10.1016/J.Jvs.2016.03.377  0.425
2016 Boniakowski A, Kimball A, Joshi A, Kunkel S, Gallagher K. Loss of a Mitochondrial Sirtuin Protein, SIRT3, Alters the Inflammatory Phase of Wound Healing Journal of the American College of Surgeons. 223: S167. DOI: 10.1016/J.Jamcollsurg.2016.06.028  0.326
2016 Kimball A, Joshi A, Ramani S, Schaller M, Chung J, Henke P, Kunkel S, Gallagher K. Blockade of Canonical Notch Signaling in Macrophages Alters the Inflammatory Response and Compounds Delayed Wound Healing in a Murine Model of Diabetes Journal of the American College of Surgeons. 223: S163. DOI: 10.1016/J.Jamcollsurg.2016.06.018  0.441
2015 Gallagher KA, Joshi A, Carson WF, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman EL, Henke PK, Hogaboam C, Burant CF, Kunkel SL. Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes. Diabetes. 64: 1420-30. PMID 25368099 DOI: 10.2337/Db14-0872  0.491
2015 Kimball A, Joshi A, Henke PK, Kunkel S, Gallagher K. PC222. Altered Histone Methylation at the IL-1B Promoter in Diabetic Macrophages Enhances Inflammation and Impairs Wound Healing Journal of Vascular Surgery. 61: 176S. DOI: 10.1016/J.Jvs.2015.04.334  0.42
2015 Chen H, Joshi A, Horne DC, Eliassen AM, Robinson ST, Coleman DM, Rectenwald JE, Kunkel S, Gallagher KA. 1. Translational Therapy Targeting Epigenetic Enzymes May Improve Wound Healing In Patients With Type 2 Diabetes Annals of Vascular Surgery. 29: 620. DOI: 10.1016/J.Avsg.2015.04.002  0.349
2014 Gallagher K, Joshi A, Hogikyan E, Coleman D, Henke P, Kunkel S. Histone Methylation Changes Result in an Unrestrained Proinflammatory M1 Macrophage Population that Delay Wound Healing in a Murine Model of Type 2 Diabetes Journal of Surgical Research. 186: 593-594. DOI: 10.1016/J.Jss.2013.11.552  0.406
2013 Byrne BG, Dubuisson JF, Joshi AD, Persson JJ, Swanson MS. Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection. Mbio. 4: e00620-12. PMID 23404401 DOI: 10.1128/Mbio.00620-12  0.536
2013 Gallagher K, Joshi A, Henke P, Feldman E, Kunkel S. Epigenetic Modifications of IL-12 Gene Expression in Bone Marrow Hematopoietic Stem Cells Promote An M1, Pro-inflammatory Phenotype in Diabetic Peripheral Macrophages Journal of Surgical Research. 179: 281. DOI: 10.1016/J.Jss.2012.10.549  0.387
2011 Joshi AD, Swanson MS. Secrets of a successful pathogen: legionella resistance to progression along the autophagic pathway. Frontiers in Microbiology. 2: 138. PMID 21743811 DOI: 10.3389/Fmicb.2011.00138  0.541
2010 Trujillo G, Meneghin A, Flaherty KR, Sholl LM, Myers JL, Kazerooni EA, Gross BH, Oak SR, Coelho AL, Evanoff H, Day E, Toews GB, Joshi AD, Schaller MA, Waters B, et al. TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis. Science Translational Medicine. 2: 57ra82. PMID 21068441 DOI: 10.1126/Scitranslmed.3001510  0.318
2010 Joshi AD, Oak SR, Hartigan AJ, Finn WG, Kunkel SL, Duffy KE, Das A, Hogaboam CM. Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages. Bmc Immunology. 11: 52. PMID 20958987 DOI: 10.1186/1471-2172-11-52  0.33
2010 Murray LA, Rosada R, Moreira AP, Joshi A, Kramer MS, Hesson DP, Argentieri RL, Mathai S, Gulati M, Herzog EL, Hogaboam CM. Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages Plos One. 5. PMID 20300636 DOI: 10.1371/Journal.Pone.0009683  0.39
2010 Fong DJ, Hogaboam CM, Matsuno Y, Akira S, Uematsu S, Joshi AD. Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis. Immunology. 130: 125-36. PMID 20070409 DOI: 10.1111/J.1365-2567.2009.03219.X  0.325
2009 Ito T, Schaller M, Raymond T, Joshi AD, Coelho AL, Frantz FG, Carson WF, Hogaboam CM, Lukacs NW, Standiford TJ, Phan SH, Chensue SW, Kunkel SL. Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation. American Journal of Respiratory and Critical Care Medicine. 180: 1227-38. PMID 19797157 DOI: 10.1164/Rccm.200906-0892Oc  0.339
2008 Joshi AD, Schaller MA, Lukacs NW, Kunkel SL, Hogaboam CM. TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung. European Journal of Immunology. 38: 3436-49. PMID 19009529 DOI: 10.1002/Eji.200838629  0.346
2008 Ishii M, Hogaboam CM, Joshi A, Ito T, Fong DJ, Kunkel SL. CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling. European Journal of Immunology. 38: 2290-302. PMID 18624303 DOI: 10.1002/Eji.200838360  0.41
2008 Joshi AD, Raymond T, Coelho AL, Kunkel SL, Hogaboam CM. A systemic granulomatous response to Schistosoma mansoni eggs alters responsiveness of bone-marrow-derived macrophages to Toll-like receptor agonists. Journal of Leukocyte Biology. 83: 314-24. PMID 18029396 DOI: 10.1189/Jlb.1007689  0.401
2001 Joshi AD, Sturgill-Koszycki S, Swanson MS. Evidence that Dot-dependent and -independent factors isolate the Legionella pneumophila phagosome from the endocytic network in mouse macrophages. Cellular Microbiology. 3: 99-114. PMID 11207624 DOI: 10.1046/J.1462-5822.2001.00093.X  0.522
1999 Joshi AD, Swanson MS. Comparative analysis of Legionella pneumophila and Legionella micdadei virulence traits. Infection and Immunity. 67: 4134-42. PMID 10417184 DOI: 10.1128/Iai.67.8.4134-4142.1999  0.517
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