Ming-Huei Chen, Ph.D. - Publications

Affiliations: 
2007 Boston University, Boston, MA, United States 
Area:
Statistics, Genetics

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Huffman JE, Nicolas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, et al. Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Medrxiv : the Preprint Server For Health Sciences. PMID 37398003 DOI: 10.1101/2023.06.07.23291095  0.572
2022 Thibord F, Klarin D, Brody JA, Chen MH, Levin MG, Chasman DI, Goode EL, Hveem K, Teder-Laving M, Martinez-Perez A, Aïssi D, Daian-Bacq D, Ito K, Natarajan P, Lutsey PL, et al. Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors. Circulation. 101161CIRCULATIONAHA. PMID 36154123 DOI: 10.1161/CIRCULATIONAHA.122.059675  0.337
2022 Pankratz N, Wei P, Brody JA, Chen MH, Vries PS, Huffman JE, Stimson MR, Auer PL, Boerwinkle E, Cushman M, Maat MPM, Folsom AR, Franco OH, Gibbs RA, Haagenson KK, et al. Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors. Human Molecular Genetics. PMID 35552711 DOI: 10.1093/hmg/ddac100  0.341
2022 Thibord F, Chan MV, Chen MH, Johnson AD. A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors. Hgg Advances. 3: 100095. PMID 35224516 DOI: 10.1016/j.xhgg.2022.100095  0.331
2021 Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, et al. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 34582791 DOI: 10.1016/j.ajhg.2021.08.007  0.355
2021 Little A, Hu Y, Sun Q, Jain D, Broome J, Chen MH, Thibord F, McHugh C, Surendran P, Blackwell TW, Brody JA, Bhan A, Chami N, Vries PS, Ekunwe L, et al. Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative. Human Molecular Genetics. PMID 34553764 DOI: 10.1093/hmg/ddab252  0.317
2021 Hu Y, Stilp AM, McHugh CP, Rao S, Jai D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, et al. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 33887194 DOI: 10.1016/j.ajhg.2021.04.003  0.356
2021 Chen MH, Pitsillides A, Yang Q. An evaluation of approaches for rare variant association analyses of binary traits in related samples. Scientific Reports. 11: 3145. PMID 33542345 DOI: 10.1038/s41598-021-82547-z  0.3
2020 Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008  0.56
2020 Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045  0.565
2020 Lee DH, Yao C, Bhan A, Schlaeger TM, Keefe J, Rodriguez BA, Hwang SJ, Chen MH, Levy D, Johnson AD. Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits. Circulation Research. PMID 32781905 DOI: 10.1161/Circresaha.119.316447  0.349
2020 Rodriguez BAT, Bhan A, Beswick A, Elwood PC, Niiranen TJ, Salomaa V, Trégouët DA, Morange PE, Civelek M, Ben-Shlomo Y, Schlaeger T, Chen MH, Johnson AD. A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling. American Journal of Human Genetics. PMID 32649856 DOI: 10.1016/J.Ajhg.2020.06.008  0.343
2019 Lindstrom S, Wang L, Smith EN, Gordon W, van Hylckama Vlieg A, de Andrade M, Brody JA, Pattee JW, Haessler J, Brumpton BM, Chasman DI, Suchon P, Chen MH, Turman C, Germain M, et al. Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism. Blood. PMID 31420334 DOI: 10.1182/Blood.2019000435  0.359
2019 Lindström S, Brody JA, Turman C, Germain M, Bartz TM, Smith EN, Chen MH, Puurunen M, Chasman D, Hassler J, Pankratz N, Basu S, Guan W, Gyorgy B, Ibrahim M, et al. A large-scale exome array analysis of venous thromboembolism. Genetic Epidemiology. PMID 30659681 DOI: 10.1002/Gepi.22187  0.434
2019 de Vries PS, Sabater-Lleal M, Huffman JE, Marten J, Song C, Pankratz N, Bartz TM, de Haan HG, Delgado GE, Eicher JD, Martinez-Perez A, Ward-Caviness CK, Brody JA, Chen MH, de Maat MPM, et al. A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology. Blood. PMID 30642921 DOI: 10.1182/Blood-2018-05-849240  0.385
2018 Weng LC, Guan W, Steffen LM, Pankow JS, Pankratz N, Chen MH, Cushman M, Basu S, Folsom AR, Tang W. Pleiotropic effects of n-6 and n-3 fatty acid-related genetic variants on circulating hemostatic variables. Thrombosis Research. 168: 53-59. PMID 29902632 DOI: 10.1016/J.Thromres.2018.05.032  0.394
2018 Jiang J, Thalamuthu A, Ho JE, Mahajan A, Ek WE, Brown DA, Breit SN, Wang TJ, Gyllensten U, Chen MH, Enroth S, Januzzi JL, Lind L, Armstrong NJ, Kwok JB, et al. A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. Frontiers in Genetics. 9: 97. PMID 29628937 DOI: 10.3389/Fgene.2018.00097  0.34
2017 Chen MH, Yanek LR, Backman JD, Eicher JD, Huffman JE, Ben-Shlomo Y, Beswick AD, Yerges-Armstrong LM, Shuldiner AR, O'Connell JR, Mathias RA, Becker DM, Becker LC, Lewis JP, Johnson AD, et al. Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation. Platelets. 1-10. PMID 29185836 DOI: 10.1080/09537104.2017.1384538  0.346
2017 Mousas A, Ntritsos G, Chen MH, Song C, Huffman JE, Tzoulaki I, Elliott P, Psaty BM, Auer PL, Johnson AD, Evangelou E, Lettre G, Reiner AP. Rare coding variants pinpoint genes that control human hematological traits. Plos Genetics. 13: e1006925. PMID 28787443 DOI: 10.1371/Journal.Pgen.1006925  0.411
2017 Gorski M, Most PJV, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, ... ... Chen MH, et al. Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Scientific Reports. 7: 46835. PMID 28548086 DOI: 10.1038/Srep46835  0.338
2017 Gorski M, van der Most PJ, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, ... ... Chen MH, et al. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Scientific Reports. 7: 45040. PMID 28452372 DOI: 10.1038/Srep45040  0.316
2017 Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJ, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, et al. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. The Journal of Clinical Investigation. PMID 28394258 DOI: 10.1172/Jci84840  0.375
2017 Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, et al. Detection of genetic loci associated with plasma fetuin-A: A meta-analysis of genome-wide association studies from the CHARGE Consortium. Human Molecular Genetics. PMID 28379451 DOI: 10.1093/Hmg/Ddx091  0.375
2017 Eicher JD, Chen MH, Pitsillides AN, Lin H, Veeraraghavan N, Brody JA, Metcalf GA, Muzny DM, Gibbs RA, Becker DM, Becker LC, Faraday N, Mathias RA, Yanek LR, Boerwinkle E, et al. Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation. Thrombosis and Haemostasis. PMID 28300864 DOI: 10.1160/Th16-09-0677  0.324
2016 Zhu QM, Ko KA, Ture S, Mastrangelo MA, Chen MH, Johnson AD, O'Donnell CJ, Morrell CN, Miano JM, Lowenstein CJ. Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28062498 DOI: 10.1161/Atvbaha.116.308614  0.346
2016 van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/J.Ajhg.2016.11.016  0.361
2016 Zhang W, Jernerén F, Lehne BC, Chen MH, Luben RN, Johnston C, Elshorbagy A, Eppinga RN, Scott WR, Adeyeye E, Scott J, Böger RH, Khaw KT, van der Harst P, Wareham NJ, et al. Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thrombosis and Haemostasis. 116. PMID 27656708 DOI: 10.1160/Th16-02-0151  0.398
2016 Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 481-488. PMID 27486782 DOI: 10.1016/J.Ajhg.2016.06.016  0.424
2016 Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, ... ... Chen MH, et al. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. American Journal of Human Genetics. PMID 27346689 DOI: 10.1016/J.Ajhg.2016.05.003  0.315
2016 Eicher JD, Chami N, Kacprowski T, Nomura A, Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N, Polfus L, Schurmann C, Giri A, Brody JA, Lange LA, et al. Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. American Journal of Human Genetics. PMID 27346686 DOI: 10.1016/J.Ajhg.2016.05.005  0.306
2016 Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, et al. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. American Journal of Human Genetics. PMID 27346685 DOI: 10.1016/J.Ajhg.2016.05.007  0.36
2016 van Loon J, Dehghan A, Weihong T, Trompet S, McArdle WL, Asselbergs FW, Chen MH, Lopez LM, Huffman JE, Leebeek FW, Basu S, Stott DJ, Rumley A, Gansevoort RT, Davies G, et al. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics : Ejhg. 24: 1096. PMID 27307114 DOI: 10.1038/Ejhg.2016.21  0.431
2015 de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S, Müller-Nurasyid M, Zhao JH, Brody JA, et al. A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration. Human Molecular Genetics. PMID 26561523 DOI: 10.1093/Hmg/Ddv454  0.431
2015 Chen MH, Yang Q. RVFam: An R Package for Rare Variant Association Analysis with Family Data. Bioinformatics (Oxford, England). PMID 26508760 DOI: 10.1093/Bioinformatics/Btv609  0.399
2015 van Loon J, Dehghan A, Weihong T, Trompet S, McArdle WL, Asselbergs FF, Chen MH, Lopez LM, Huffman JE, Leebeek FW, Basu S, Stott DJ, Rumley A, Gansevoort RT, Davies G, et al. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics : Ejhg. PMID 26486471 DOI: 10.1038/Ejhg.2015.222  0.338
2015 Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, et al. Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nature Genetics. PMID 26301497 DOI: 10.1038/Ng.3383  0.316
2015 Huffman JE, de Vries PS, Morrison AC, Sabater-Lleal M, Kacprowski T, Auer PL, Brody JA, Chasman DI, Chen MH, Guo X, Lin LA, Marioni RE, Müller-Nurasyid M, Yanek LR, Pankratz N, et al. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 126: e19-29. PMID 26105150 DOI: 10.1182/Blood-2015-02-624551  0.336
2015 Musani SK, Fox ER, Kraja A, Bidulescu A, Lieb W, Lin H, Beecham A, Chen MH, Felix JF, Fox CS, Kao WH, Kardia SL, Liu CT, Nalls MA, Rundek T, et al. Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study. Circulation. Cardiovascular Genetics. 8: 122-30. PMID 25561047 DOI: 10.1161/Circgenetics.114.000900  0.34
2015 Lieb W, Chen MH, Teumer A, de Boer RA, Lin H, Fox ER, Musani SK, Wilson JG, Wang TJ, Völzke H, Petersen AK, Meisinger C, Nauck M, Schlesinger S, Li Y, et al. Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. Circulation. Cardiovascular Genetics. 8: 131-40. PMID 25477429 DOI: 10.1161/Circgenetics.114.000613  0.416
2014 Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, et al. Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics. 23: 6944-60. PMID 25096241 DOI: 10.1093/hmg/ddu401  0.372
2014 Huang J, Huffman JE, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, ... ... Chen MH, et al. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1093-101. PMID 24578379 DOI: 10.1161/Atvbaha.113.302088  0.31
2013 Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, et al. Common variants in Mendelian kidney disease genes and their association with renal function. Journal of the American Society of Nephrology : Jasn. 24: 2105-17. PMID 24029420 DOI: 10.1681/Asn.2012100983  0.316
2013 Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, et al. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. The Journal of Clinical Investigation. 123: 4208-18. PMID 23999434 DOI: 10.1172/Jci67119  0.335
2013 Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, ... ... Chen MH, et al. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 128: 1310-24. PMID 23969696 DOI: 10.1161/Circulationaha.113.002251  0.328
2013 Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, et al. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metabolism. 18: 130-43. PMID 23823483 DOI: 10.1016/J.Cmet.2013.06.013  0.421
2013 Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Ritchie MD, Saip A, Crawford DC, ... Chen MH, et al. Genetic variation associated with circulating monocyte count in the eMERGE Network. Human Molecular Genetics. 22: 2119-27. PMID 23314186 DOI: 10.1093/Hmg/Ddt010  0.314
2012 Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q. Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. Plos One. 7: e51589. PMID 23284720 DOI: 10.1371/Journal.Pone.0051589  0.433
2012 Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, ... ... Chen MH, et al. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 120: 4873-81. PMID 22990020 DOI: 10.1182/Blood-2012-06-436188  0.329
2011 Chen MH, Liu X, Wei F, Larson MG, Fox CS, Vasan RS, Yang Q. A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. Genetic Epidemiology. 35: 650-7. PMID 21818773 DOI: 10.1002/Gepi.20614  0.377
2011 Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, et al. Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood. 118: 3367-75. PMID 21791418 DOI: 10.1182/Blood-2010-11-320788  0.403
2011 Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, et al. Multiple loci are associated with white blood cell phenotypes. Plos Genetics. 7: e1002113. PMID 21738480 DOI: 10.1371/Journal.Pgen.1002113  0.317
2011 Okada Y, Hirota T, Kamatani Y, Takahashi A, Ohmiya H, Kumasaka N, Higasa K, Yamaguchi-Kabata Y, Hosono N, Nalls MA, Chen MH, van Rooij FJ, Smith AV, Tanaka T, Couper DJ, et al. Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. Plos Genetics. 7: e1002067. PMID 21738478 DOI: 10.1371/Journal.Pgen.1002067  0.345
2011 Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin SY, Baumert J, Vitart V, Bis JC, Wild SH, Rumley A, Yang Q, Uitterlinden AG, ... ... Chen MH, et al. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation. 123: 1864-72. PMID 21502573 DOI: 10.1161/Circulationaha.110.009480  0.406
2010 Chen MH, Larson MG, Hsu YH, Peloso GM, Guo CY, Fox CS, Atwood LD, Yang Q. A three-stage approach for genome-wide association studies with family data for quantitative traits. Bmc Genetics. 11: 40. PMID 20470424 DOI: 10.1186/1471-2156-11-40  0.398
2010 Musunuru K, Lettre G, Young T, Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q, Chen MH, Lapchyk N, Crenshaw A, Ziaugra L, Rachupka A, Benjamin EJ, Cupples LA, et al. Candidate gene association resource (CARe): design, methods, and proof of concept. Circulation. Cardiovascular Genetics. 3: 267-75. PMID 20400780 DOI: 10.1161/Circgenetics.109.882696  0.389
2010 Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 121: 1382-92. PMID 20231535 DOI: 10.1161/Circulationaha.109.869156  0.385
2010 Chen MH, Yang Q. GWAF: an R package for genome-wide association analyses with family data. Bioinformatics (Oxford, England). 26: 580-1. PMID 20040588 DOI: 10.1093/Bioinformatics/Btp710  0.419
2010 Chen MH, Van Eerdewegh P, Vincent QB, Alcais A, Abel L, Dupuis J. Evaluation of approaches to identify associated SNPs that explain the linkage evidence in nuclear families with affected siblings. Human Heredity. 69: 104-19. PMID 19996608 DOI: 10.1159/000264448  0.564
2009 Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, et al. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circulation. Cardiovascular Genetics. 2: 229-37. PMID 20031590 DOI: 10.1161/Circgenetics.108.804245  0.544
2009 Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, et al. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circulation. Cardiovascular Genetics. 2: 125-33. PMID 20031576 DOI: 10.1161/Circgenetics.108.825224  0.434
2009 Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, Nalls MA, Chen MH, Kottgen A, Glazer NL, Dehghan A, Kuhnel B, Aspelund T, Yang Q, Tanaka T, Jaffe A, et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nature Genetics. 41: 1191-8. PMID 19862010 DOI: 10.1038/Ng.466  0.347
2009 Johnson AD, Kavousi M, Smith AV, Chen MH, Dehghan A, Aspelund T, Lin JP, van Duijn CM, Harris TB, Cupples LA, Uitterlinden AG, Launer L, Hofman A, Rivadeneira F, Stricker B, et al. Genome-wide association meta-analysis for total serum bilirubin levels. Human Molecular Genetics. 18: 2700-10. PMID 19414484 DOI: 10.1093/Hmg/Ddp202  0.477
2007 Chen MH, Cui J, Guo CY, Cupples LA, Van Eerdewegh P, Dupuis J, Yang Q. Joint modeling of linkage and association using affected sib-pair data. Bmc Proceedings. 1: S38. PMID 18466536 DOI: 10.1186/1753-6561-1-S1-S38  0.542
2007 Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC, Cupples LA, Apprey V, Cui J, et al. Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genetic Epidemiology. 31: S34-42. PMID 18046758 DOI: 10.1002/Gepi.20278  0.523
2005 Chen MH, Van Eerdewegh P, Dupuis J. Identification of polymorphisms explaining a linkage signal: application to the GAW14 simulated data. Bmc Genetics. 6: S88. PMID 16451703 DOI: 10.1186/1471-2156-6-S1-S88  0.54
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