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Antonios Pantazis, PhD - Publications

Affiliations: 
ANESTHESIOLOGY University of California, Los Angeles, Los Angeles, CA 
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55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mínguez-Viñas T, Prakash V, Wang K, Lindström SH, Pozzi S, Scott SA, Spiteri E, Stevenson DA, Ashley EA, Gunnarsson C, Pantazis A. Two epilepsy-associated variants in KCNA2 (K 1.2) at position H310 oppositely affect channel functional expression. The Journal of Physiology. PMID 37883018 DOI: 10.1113/JP285052  0.356
2023 Nilsson M, Wang K, Minguez Vinas T, Berglund S, Pantazis A. Gβγ induces reluctant VSD-I activation in Ca2.2 (n-type) voltage-gated calcium channels. Biophysical Journal. 122: 310a-311a. PMID 36783559 DOI: 10.1016/j.bpj.2022.11.1745  0.435
2023 Angelini M, McVicar M, Savalli N, John SA, Neely A, Pantazis A, Ottolia M, Olcese R. The voltage-dependent structural transitions governing the opening of the human t-type Cav3.1 channel: Insights from voltage-clamp fluorometry. Biophysical Journal. 122: 107a. PMID 36782464 DOI: 10.1016/j.bpj.2022.11.760  0.643
2023 Wang K, Nilsson M, Elinder F, Pantazis A. Ca2.1 channels divide into two populations at resting membrane potentials. Biophysical Journal. 122: 104a. PMID 36782451 DOI: 10.1016/j.bpj.2022.11.749  0.336
2022 Nilsson M, Lindström SH, Kaneko M, Wang K, Minguez-Viñas T, Angelini M, Steccanella F, Holder D, Ottolia M, Olcese R, Pantazis A. An epilepsy-associated K1.2 charge-transfer-center mutation impairs K1.2 and K1.4 trafficking. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113675119. PMID 35439054 DOI: 10.1073/pnas.2113675119  0.765
2021 Angelini M, Pezhouman A, Savalli N, Chang MG, Steccanella F, Scranton K, Calmettes G, Ottolia M, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Suppression of ventricular arrhythmias by targeting late L-type Ca2+ current. The Journal of General Physiology. 153. PMID 34698805 DOI: 10.1085/jgp.202012584  0.815
2020 Pantazis A, Kaneko M, Angelini M, Steccanella F, Westerlund AM, Lindström SH, Nilsson M, Delemotte L, Saitta SC, Olcese R. Tracking the motion of K 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy. The Journal of Physiology. PMID 32833227 DOI: 10.1113/Jp280438  0.793
2020 Angelini M, Pezhouman A, Savalli N, Chang M, Calmettes G, Steccanella F, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Potent Suppression of Ventricular Arrhythmias by Selectively Targeting Late L-type Calcium Current Biophysical Journal. 118: 104a. DOI: 10.1016/J.Bpj.2019.11.723  0.77
2019 Seki S, Yamamoto T, Quinn K, Spigelman I, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH, Venugopal S. Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1 Mouse Model for ALS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31530644 DOI: 10.1523/Jneurosci.1214-19.2019  0.557
2019 Venugopal S, Seki S, Terman DH, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH. Resurgent Na+ Current Offers Noise Modulation in Bursting Neurons. Plos Computational Biology. 15: e1007154. PMID 31226124 DOI: 10.1371/Journal.Pcbi.1007154  0.605
2019 Pantazis A, Kaneko M, Westerlund AM, Delemotte L, Saitta S, Olcese R. A De Novo Mutation Associated with Epilepsy Enhances KV1.2 Voltage Dependence, Suppressing Neuronal Excitability Biophysical Journal. 116: 247a. DOI: 10.1016/J.Bpj.2018.11.1351  0.598
2018 Pantazis A, Westerberg K, Althoff T, Abramson J, Olcese R. Harnessing photoinduced electron transfer to optically determine protein sub-nanoscale atomic distances. Nature Communications. 9: 4738. PMID 30413716 DOI: 10.1038/S41467-018-07218-6  0.62
2018 Angelini M, Pezhouman A, Chang MG, Savalli N, Calmettes G, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. L-Type Calcium Channel Gating Modifiers as a New Class of Antiarrhythmic Drugs Biophysical Journal. 114: 623a. DOI: 10.1016/J.Bpj.2017.11.3370  0.809
2018 Pantazis A, Olcese R. Resolving the BK Channel Voltage Sensor Activation Transition with Relative Atomic Coordinates Under Physiologically-Relevant Conditions Biophysical Journal. 114: 545a. DOI: 10.1016/J.Bpj.2017.11.2980  0.647
2017 Yusifov T, Savalli N, Pantazis A, Heinemann SH, Hoshi T, Olcese R. Carbon Monoxide May Regulate BK slo1 Channel Activity by Partially Disrupting Heme Coordination Biophysical Journal. 112: 112a. DOI: 10.1016/J.Bpj.2016.11.631  0.782
2017 Contreras GF, Savalli N, Pantazis A, Gonzalez C, Olcese R, Neely A. The Calcium Channel A2D Subunit Increases the Gating Charges of Ca v 1.2 Channels Biophysical Journal. 112: 108a. DOI: 10.1016/J.Bpj.2016.11.614  0.823
2017 Pantazis A, Sigg D, Neely A, Olcese R. Optically Probing the Mechanism of Voltage-Dependent Facilitation in Ca V 1.2 Channels Biophysical Journal. 112: 244a-245a. DOI: 10.1016/J.Bpj.2016.11.1337  0.712
2017 Angelini M, Pezhouman A, Savalli N, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. A New Class of Antiarrhythmics for Late I CA,L Biophysical Journal. 112: 234a-235a. DOI: 10.1016/J.Bpj.2016.11.1285  0.823
2016 Savalli N, Pantazis A, Sigg D, Weiss JN, Neely A, Olcese R. The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials. The Journal of General Physiology. 148: 147-59. PMID 27481713 DOI: 10.1085/Jgp.201611586  0.839
2016 Pantazis A, Olcese R. Biophysics of BK Channel Gating. International Review of Neurobiology. 128: 1-49. PMID 27238260 DOI: 10.1016/Bs.Irn.2016.03.013  0.706
2016 Pantazis A, Olcese R. Distance-Resolving Voltage Clamp Fluorometry (drVCF) Quantifies Intramolecular Transitions in the Human BK and CI-VSP Voltage Sensors Under Physiologically-Relevant Conditions Biophysical Journal. 110: 103a. DOI: 10.1016/J.Bpj.2015.11.615  0.617
2016 Savalli N, Angelini M, Pantazis A, Yusifov T, Neely A, Olcese R. Eminence of VSD I in the Voltage-Dependent Inactivation of the Human CaV1.2 Channel Biophysical Journal. 110: 444a. DOI: 10.1016/J.Bpj.2015.11.2388  0.841
2016 Angelini M, Pezhouman A, Savalli N, Pantazis A, Melkonian A, Weiss JN, Karagueuzian HS, Olcese R. Roscovitine as the Archetypal Member of a Novel Class of Antiarrhythmics Targeting Late ICa,L Biophysical Journal. 110: 272a. DOI: 10.1016/J.Bpj.2015.11.1478  0.809
2015 Madhvani RV, Angelini M, Xie Y, Pantazis A, Suriany S, Borgstrom NP, Garfinkel A, Qu Z, Weiss JN, Olcese R. Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations. The Journal of General Physiology. 145: 395-404. PMID 25918358 DOI: 10.1085/Jgp.201411288  0.823
2015 Yusifov T, Savalli N, Park S, Pantazis A, Olcese R. The Role of Met-691 in Heme-Dependent Regulation Supports the Presence of a Cytochrome-C-Like Structure in Human BK Channels Biophysical Journal. 108: 121a-122a. DOI: 10.1016/J.Bpj.2014.11.681  0.803
2015 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Efficiently Couples VSDs Activation to Pore Opening in Human Cav1.2 Channels Biophysical Journal. 108: 581a. DOI: 10.1016/J.Bpj.2014.11.3173  0.824
2015 Pantazis A, Olcese R. Enhanced Voltage-Clamp Fluorometry Assigns Distance Constraints to BK Channel VSD Structural Transitions Biophysical Journal. 108: 23a. DOI: 10.1016/J.Bpj.2014.11.152  0.612
2014 Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 111: 18381-6. PMID 25489110 DOI: 10.1073/Pnas.1411127112  0.831
2014 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Facilitates CaV1.2 Channel Activation by Remodeling Its Four Voltage Sensor Domains Biophysical Journal. 106: 135a. DOI: 10.1016/J.Bpj.2013.11.791  0.824
2014 Sigg D, Shieh R, Pantazis A, Savalli N, Olcese R. Hill Analysis of Ion Channel Activation: Theory and Practice Biophysical Journal. 106: 134a-135a. DOI: 10.1016/J.Bpj.2013.11.789  0.771
2014 Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. The Functional Heterogeneity of the Human CaV1.2 Voltage Sensors Biophysical Journal. 106: 134a. DOI: 10.1016/J.Bpj.2013.11.786  0.807
2014 Yusifov T, Savalli N, Pantazis A, Olcese R. Enzymatic Activity of the Human BK Channel: A Function Beyond Electrical Signaling Biophysical Journal. 106: 535a. DOI: 10.1016/J.Bpj.2013.11.2986  0.793
2014 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. A Timothy Syndrome Causing Mutation Perturbs Voltage Sensor Operation in Human CaV1.2 Channels Biophysical Journal. 106: 330a-331a. DOI: 10.1016/J.Bpj.2013.11.1898  0.831
2013 Hoshi T, Pantazis A, Olcese R. Transduction of voltage and Ca2+ signals by Slo1 BK channels. Physiology (Bethesda, Md.). 28: 172-89. PMID 23636263 DOI: 10.1152/Physiol.00055.2012  0.713
2013 Yusifov T, Gandhi CS, Pantazis A, Olcese R. Structural Studies of the Apo and Ca2+-Bound States of the Human BK (SLO1) Channel Gating Ring in Solution Biophysical Journal. 104: 473a. DOI: 10.1016/J.Bpj.2012.11.2614  0.659
2013 Pantazis A, Savalli N, Neely A, Olcese R. Optically-Resolved Conformational Rearrangements of the Voltage-Sensing Domains of the Human CaV1.2 Channel Biophysical Journal. 104: 358a-359a. DOI: 10.1016/J.Bpj.2012.11.1992  0.836
2013 Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Tuning L-Type Ca2+ Current Properties to Suppress Early After depolarizations Biophysical Journal. 104: 295a. DOI: 10.1016/J.Bpj.2012.11.1646  0.833
2013 Pantazis A, Savalli N, Olcese R. The Activation Transition of the Human BK (Slo1) Voltage Sensor Involves a Complex Rearrangement of its Helix Bundle as Resolved by Site-Directed Fluorophore/Quencher Pairs Biophysical Journal. 104: 197a. DOI: 10.1016/J.Bpj.2012.11.1112  0.799
2012 Pantazis A, Olcese R. Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing. The Journal of General Physiology. 140: 207-18. PMID 22802360 DOI: 10.1085/Jgp.201210807  0.683
2012 Savalli N, Pantazis A, Yusifov T, Sigg D, Olcese R. The contribution of RCK domains to human BK channel allosteric activation. The Journal of Biological Chemistry. 287: 21741-50. PMID 22556415 DOI: 10.1074/Jbc.M112.346171  0.811
2012 Pantazis A, Xu L, Sigg D, Olcese R. Probing the Allosteric Interactions that Mediate Voltage-Dependent BK (Slo1) Channel Activation with a Pore Blocker Biophysical Journal. 102: 688a. DOI: 10.1016/J.Bpj.2011.11.3740  0.725
2012 Pantazis A, Olcese R. The Mechanics of Voltage Sensing in the Human BK Channel (Slo1) Biophysical Journal. 102: 688a. DOI: 10.1016/J.Bpj.2011.11.3739  0.693
2012 Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. How do L-Type Calcium Current Kinetics Contribute to Early After Depolarizations in Cardiac Myocytes? Biophysical Journal. 102: 541a. DOI: 10.1016/J.Bpj.2011.11.2956  0.816
2011 Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes. The Journal of Physiology. 589: 6081-92. PMID 22025660 DOI: 10.1113/Jphysiol.2011.219600  0.822
2011 Javaherian AD, Yusifov T, Pantazis A, Franklin S, Gandhi CS, Olcese R. Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus. The Journal of Biological Chemistry. 286: 20701-9. PMID 21471215 DOI: 10.1074/Jbc.M111.235234  0.685
2011 Pantazis A, Kohanteb A, Olcese R. Probing the Dynamic Structure of the BKCa Voltage Sensor: Relative Motion of Segments S0 & S4 During Activation Biophysical Journal. 100: 581a. DOI: 10.1016/J.Bpj.2010.12.3360  0.683
2011 Yusifov T, Javaherian A, Pantazis A, Gandhi C, Olcese R. On the Properties of the RCK1 Domain of the Human BK (SLO1) Channel Biophysical Journal. 100: 581a. DOI: 10.1016/J.Bpj.2010.12.3359  0.623
2011 Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. Suppressing Early Afterdepolarizations in Cardiac Myocytes by Shaping a Modified Ca2+ Conductance Under Dynamic Clamp Biophysical Journal. 100: 439a. DOI: 10.1016/J.Bpj.2010.12.2584  0.828
2010 Pantazis A, Kohanteb AP, Olcese R. Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channel. The Journal of General Physiology. 136: 645-57. PMID 21078868 DOI: 10.1085/Jgp.201010503  0.701
2010 Yusifov T, Javaherian AD, Pantazis A, Gandhi CS, Olcese R. The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements. The Journal of General Physiology. 136: 189-202. PMID 20624858 DOI: 10.1085/Jgp.200910374  0.651
2010 Pantazis A, Gudzenko V, Savalli N, Sigg D, Olcese R. Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 107: 4459-64. PMID 20160086 DOI: 10.1073/Pnas.0911959107  0.82
2010 Pantazis A, Kohanteb A, Olcese R. Voltage-Dependent Motions Reported from the N-Terminal Region in Human Slo1 BKCa Channels: S0 and Voltage Sensor Operation Biophysical Journal. 98: 127a. DOI: 10.1016/J.Bpj.2009.12.688  0.707
2009 Pantazis A, Gudzenko V, Savalli N, Kohanteb A, Sigg D, Olcese R. Cooperativity Between Voltage-sensing Domains in the Human BK Channel Revealed by Voltage-clamp Fluorometry. Biophysical Journal. 96: 481a. DOI: 10.1016/J.Bpj.2008.12.2480  0.813
2008 Pantazis A, Segaran A, Liu CH, Nikolaev A, Rister J, Thum AS, Roeder T, Semenov E, Juusola M, Hardie RC. Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7250-9. PMID 18632929 DOI: 10.1523/Jneurosci.1654-08.2008  0.617
2006 Pantazis A, Keegan P, Postma M, Schwiening CJ. The effect of neuronal morphology and membrane-permeant weak acid and base on the dissipation of depolarization-induced pH gradients in snail neurons. Pflã¼Gers Archiv : European Journal of Physiology. 452: 175-87. PMID 16341877 DOI: 10.1007/S00424-005-0019-4  0.448
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