Tang-Long Shen, Ph.D. - Publications

Affiliations: 
2003 Cornell University, Ithaca, NY, United States 
Area:
Cell Biology, Biochemistry

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tai YL, Lin CJ, Li TK, Shen TL, Hsieh JT, Chen BPC. The role of extracellular vesicles in prostate cancer with clinical applications. Endocrine-Related Cancer. PMID 32203935 DOI: 10.1530/Erc-20-0021  0.333
2020 Hung IC, Chen TM, Lin JP, Tai YL, Shen TL, Lee SJ. Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42. Open Biology. 10: 190273. PMID 32097584 DOI: 10.1098/Rsob.190273  0.421
2019 Lin CJ, Yun EJ, Lo UG, Tai YL, Deng S, Hernandez E, Dang A, Chen YA, Saha D, Mu P, Lin H, Li TK, Shen TL, Lai CH, Hsieh JT. The paracrine induction of prostate cancer progression by caveolin-1. Cell Death & Disease. 10: 834. PMID 31685812 DOI: 10.1038/S41419-019-2066-3  0.338
2019 Wu PY, Yu IS, Lin YC, Chang YT, Chen CC, Lin KH, Tseng TH, Kargren M, Tai YL, Shen TL, Liu YL, Wang BJ, Chang CH, Chen WM, Juan HF, et al. Activation of Aryl Hydrocarbon Receptor by Kynurenine Impairs Progression and Metastasis of Neuroblastoma. Cancer Research. PMID 31431462 DOI: 10.1158/0008-5472.Can-18-3272  0.341
2019 Chu PY, Tai YL, Shen TL. Grb7, a Critical Mediator of EGFR/ErbB Signaling, in Cancer Development and as a Potential Therapeutic Target. Cells. 8. PMID 31083325 DOI: 10.3390/Cells8050435  0.383
2018 Lin YC, Chen CC, Chen WM, Lu KY, Shen TL, Jou YC, Shen CH, Ohbayashi N, Kanaho Y, Huang YL, Lee H. LPA signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Biochimica Et Biophysica Acta. PMID 30053596 DOI: 10.1016/J.Bbalip.2018.07.005  0.383
2016 Tai YL, Tung LH, Lin YC, Lu PJ, Chu PY, Wang MY, Huang WP, Chen KC, Lee H, Shen TL. Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression. Plos One. 11: e0163617. PMID 27658202 DOI: 10.1371/journal.pone.0163617  0.308
2016 Tai YL, Lai IR, Peng YJ, Ding ST, Shen TL. Activation of focal adhesion kinase through an interaction with β4 integrin contributes to tumorigenicity of colon cancer. Febs Letters. PMID 27178753 DOI: 10.1002/1873-3468.12215  0.351
2015 Tai YL, Chu PY, Lai IR, Wang MY, Tseng HY, Guan JL, Liou JY, Shen TL. An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer. Scientific Reports. 5: 16408. PMID 26549523 DOI: 10.1038/Srep16408  0.521
2015 Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, et al. Tumour exosome integrins determine organotropic metastasis. Nature. PMID 26524530 DOI: 10.1038/Nature15756  0.363
2015 Chou SM, Lai WJ, Hong T, Tsai SH, Chen YH, Kao CH, Chu R, Shen TL, Li TK. Involvement of p38 MAPK in the Anticancer Activity of Cultivated Cordyceps militaris. The American Journal of Chinese Medicine. 43: 1043-57. PMID 26205966 DOI: 10.1142/S0192415X15500603  0.374
2015 Tai YL, Chen LC, Shen TL. Emerging roles of focal adhesion kinase in cancer. Biomed Research International. 2015: 690690. PMID 25918719 DOI: 10.1155/2015/690690  0.448
2014 Yao WL, Ko BS, Liu TA, Liang SM, Liu CC, Lu YJ, Tzean SS, Shen TL, Liou JY. Cordycepin suppresses integrin/FAK signaling and epithelial-mesenchymal transition in hepatocellular carcinoma. Anti-Cancer Agents in Medicinal Chemistry. 14: 29-34. PMID 23855336 DOI: 10.2174/18715206113139990305  0.397
2013 Ko BS, Lu YJ, Yao WL, Liu TA, Tzean SS, Shen TL, Liou JY. Cordycepin regulates GSK-3β/β-catenin signaling in human leukemia cells. Plos One. 8: e76320. PMID 24086728 DOI: 10.1371/Journal.Pone.0076320  0.366
2013 Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D. Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L291-300. PMID 23771883 DOI: 10.1152/Ajplung.00094.2013  0.551
2013 Tai Y, Shen T. Abstract C44: Activation of focal adhesion kinase by direct interaction with β4 integrin in an EGFR-Src-dependent pathway in tumor progression Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C44  0.418
2012 Hsu CH, Shen TL, Chang CF, Chang YY, Huang LY. Solution structure of the oncogenic MIEN1 protein reveals a thioredoxin-like fold with a redox-active motif. Plos One. 7: e52292. PMID 23284973 DOI: 10.1371/Journal.Pone.0052292  0.362
2012 Lin CE, Chen SU, Lin CC, Chang CH, Lin YC, Tai YL, Shen TL, Lee H. Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells. Plos One. 7: e41096. PMID 22911748 DOI: 10.1371/Journal.Pone.0041096  0.345
2012 Chang TC, Liu CC, Hsing EW, Liang SM, Chi YH, Sung LY, Lin SP, Shen TL, Ko BS, Yen BL, Yet SF, Wu KK, Liou JY. 14-3-3σ regulates β-catenin-mediated mouse embryonic stem cell proliferation by sequestering GSK-3β. Plos One. 7: e40193. PMID 22768254 DOI: 10.1371/Journal.Pone.0040193  0.339
2012 Li T, Yang Y, Shen T. Abstract LB-394: Type II topoisomerases contribute to nitric oxide-induced DNA breakage during cancer-related inflammation Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-394  0.304
2012 Chu P, Li T, Chou K, Shen T. Abstract LB-28: A co-op of EGFR and EphA4 promotes the progression of NSCLC through EGF-Grb7-Stat3 mediated transcriptional regulation of EphA4 gene expression Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-28  0.43
2012 Thennes T, Tauseef M, Bonini M, Gothert J, Shen T, Guan J, Sadikot R, Mehta D. Endothelial Focal adhesion kinase maintains lung fluid balance and prevents cytokine storm The Faseb Journal. 26. DOI: 10.1096/Fasebj.26.1_Supplement.1063.8  0.549
2010 Lai IR, Chu PY, Lin HS, Liou JY, Jan YJ, Lee JC, Shen TL. Phosphorylation of focal adhesion kinase at Tyr397 in gastric carcinomas and its clinical significance. The American Journal of Pathology. 177: 1629-37. PMID 20724588 DOI: 10.2353/Ajpath.2010.100172  0.357
2010 Chu PY, Li TK, Ding ST, Lai IR, Shen TL. EGF-induced Grb7 recruits and promotes Ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells. The Journal of Biological Chemistry. 285: 29279-85. PMID 20622016 DOI: 10.1074/Jbc.C110.114124  0.377
2010 Yang CJ, Chang CF, Huang LY, Chang YY, Shen TL, Hsu CH. Resonance assignments of human C35 (C17orf37) protein, a novel tumor biomarker. Biomolecular Nmr Assignments. 4: 191-3. PMID 20556552 DOI: 10.1007/S12104-010-9218-9  0.3
2010 Fan JR, Huang TH, Wen CY, Shen TL, Li TK. Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses. European Journal of Pharmacology. 638: 13-20. PMID 20406630 DOI: 10.1016/J.Ejphar.2010.04.012  0.37
2010 Ko BS, Chang TC, Chen CH, Liu CC, Kuo CC, Hsu C, Shen YC, Shen TL, Golubovskaya VM, Chang CC, Shyue SK, Liou JY. Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappa B. Life Sciences. 86: 199-206. PMID 20006625 DOI: 10.1016/J.Lfs.2009.12.003  0.426
2009 Chu PY, Huang LY, Hsu CH, Liang CC, Guan JL, Hung TH, Shen TL. Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis. The Journal of Biological Chemistry. 284: 20215-26. PMID 19473962 DOI: 10.1074/jbc.M109.018259  0.597
2009 Park AY, Shen TL, Chien S, Guan JL. Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis. The Journal of Biological Chemistry. 284: 9418-25. PMID 19201755 DOI: 10.1074/Jbc.M809040200  0.617
2008 Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. The Journal of Cell Biology. 181: 43-50. PMID 18391070 DOI: 10.1083/Jcb.200710038  0.6
2008 Huang H, Chen H, Chen C, Shen T, Huang J, Lin N, Sum S, Che M, Huang M. Ammonium Hydroxide Extracts From Black Tea Inhibit Growth, Migration And Invasion Of Colon Cancer Cells Journal of Food Biochemistry. 32: 201-215. DOI: 10.1111/J.1745-4514.2008.00152.X  0.422
2007 Nagy T, Wei H, Shen TL, Peng X, Liang CC, Gan B, Guan JL. Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland. The Journal of Biological Chemistry. 282: 31766-76. PMID 17716968 DOI: 10.1074/Jbc.M705403200  0.695
2007 Huang J, Liang JT, Huang HC, Shen TL, Chen HY, Lin NY, Che MI, Lin WC, Huang MC. Beta1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cells. Molecular Cancer Research : McR. 5: 543-52. PMID 17579116 DOI: 10.1158/1541-7786.Mcr-06-0431  0.419
2006 Peng X, Kraus MS, Wei H, Shen TL, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan JL. Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. The Journal of Clinical Investigation. 116: 217-27. PMID 16374517 DOI: 10.1172/Jci24497  0.478
2005 Shen TL, Park AY, Alcaraz A, Peng X, Jang I, Koni P, Flavell RA, Gu H, Guan JL. Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. The Journal of Cell Biology. 169: 941-52. PMID 15967814 DOI: 10.1083/Jcb.200411155  0.556
2005 Miao H, Strebhardt K, Pasquale EB, Shen TL, Guan JL, Wang B. Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases. The Journal of Biological Chemistry. 280: 923-32. PMID 15536074 DOI: 10.1074/jbc.M411383200  0.59
2004 Peng X, Ueda H, Zhou H, Stokol T, Shen TL, Alcaraz A, Nagy T, Vassalli JD, Guan JL. Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice. Cardiovascular Research. 64: 421-30. PMID 15537495 DOI: 10.1016/J.Cardiores.2004.07.012  0.664
2004 Li W, Lee J, Vikis HG, Lee SH, Liu G, Aurandt J, Shen TL, Fearon ER, Guan JL, Han M, Rao Y, Hong K, Guan KL. Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nature Neuroscience. 7: 1213-21. PMID 15494734 DOI: 10.1038/Nn1329  0.51
2004 Shen TL, Guan JL. Grb7 in intracellular signaling and its role in cell regulation. Frontiers in Bioscience : a Journal and Virtual Library. 9: 192-200. PMID 14766359 DOI: 10.2741/1229  0.584
2003 Cooper LA, Shen TL, Guan JL. Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction. Molecular and Cellular Biology. 23: 8030-41. PMID 14585964 DOI: 10.1128/Mcb.23.22.8030-8041.2003  0.609
2002 Han DC, Shen TL, Miao H, Wang B, Guan JL. EphB1 associates with Grb7 and regulates cell migration. The Journal of Biological Chemistry. 277: 45655-61. PMID 12223469 DOI: 10.1074/jbc.M203165200  0.564
2002 Shen TL, Han DC, Guan JL. Association of Grb7 with phosphoinositides and its role in the regulation of cell migration. The Journal of Biological Chemistry. 277: 29069-77. PMID 12021278 DOI: 10.1074/Jbc.M203085200  0.594
2002 Goicoechea SM, Tu Y, Hua Y, Chen K, Shen TL, Guan JL, Wu C. Nck-2 interacts with focal adhesion kinase and modulates cell motility. The International Journal of Biochemistry & Cell Biology. 34: 791-805. PMID 11950595 DOI: 10.1016/S1357-2725(02)00002-X  0.59
2001 Han DC, Shen TL, Guan JL. The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions. Oncogene. 20: 6315-21. PMID 11607834 DOI: 10.1038/Sj.Onc.1204775  0.559
2001 Shen TL, Guan JL. Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts. Febs Letters. 499: 176-81. PMID 11418135 DOI: 10.1016/S0014-5793(01)02545-5  0.608
2000 Han DC, Shen TL, Guan JL. Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration. The Journal of Biological Chemistry. 275: 28911-7. PMID 10893408 DOI: 10.1074/Jbc.M001997200  0.621
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