Nicholas Mantis - Publications

Affiliations: 
Biomedical Sciences State University of New York, Albany, Albany, NY, United States 
Area:
Microbiology Biology

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim JS, Sun Y, Balte P, Cushman M, Boyle R, Tracy RP, Styer LM, Bell TD, Anderson MR, Allen NB, Schreiner PJ, Bowler RP, Schwartz DA, Lee JS, Xanthakis V, ... ... Mantis NJ, et al. Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study. Nature Communications. 15: 1492. PMID 38374032 DOI: 10.1038/s41467-024-45468-9  0.408
2023 Heaney CD, Hempel H, DeRosa KL, Pinto LA, Mantis NJ. Clinical Assessment of SARS-CoV-2 Antibodies in Oral Fluids Following Infection and Vaccination. Clinical Chemistry. PMID 38039096 DOI: 10.1093/clinchem/hvad169  0.469
2023 Baqar S, Bonavia A, Louis Bourgeois A, Campo JJ, Clifford A, Hanevik K, Hasso-Agopsowicz M, Hausdorff W, Kaminski R, MacLennan CA, Mantis N, Martin LB, Omore R, Pasetti M, Pavlinac P, et al. The 2022 Vaccines Against Shigella and Enterotoxigenic Escherichia coli (VASE) Conference: Summary of breakout workshops. Vaccine. PMID 38036392 DOI: 10.1016/j.vaccine.2023.11.045  0.31
2023 Sobhani K, Cheng S, Binder RA, Mantis NJ, Crawford JM, Okoye N, Braun JG, Joung S, Wang M, Lozanski G, King CL, Roback JD, Granger DA, Boppana SB, Karger AB. Clinical Utility of SARS-CoV-2 Serological Testing and Defining a Correlate of Protection. Vaccines. 11. PMID 38005976 DOI: 10.3390/vaccines11111644  0.505
2023 Kumru OS, Bajoria S, Kaur K, Hickey JM, Van Slyke G, Doering J, Berman K, Richardson C, Lien H, Kleanthous H, Mantis NJ, Joshi SB, Volkin DB. Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD). Human Vaccines & Immunotherapeutics. 19: 2264594. PMID 37932241 DOI: 10.1080/21645515.2023.2264594  0.357
2023 Deal CE, Richards AF, Yeung T, Maron MJ, Wang Z, Lai YT, Fritz BR, Himansu S, Narayanan E, Liu D, Koleva R, Licht S, Hsiao CJ, Rajlic IL, Koch H, ... ... Mantis NJ, et al. An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions. Cell Reports. Medicine. 101253. PMID 37918405 DOI: 10.1016/j.xcrm.2023.101253  0.309
2023 Vance DJ, Rudolph MJ, Davis SA, Mantis NJ. Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells. Biochemistry. PMID 37903428 DOI: 10.1021/acs.biochem.3c00480  0.345
2023 Hempel H, Mantis N, Heaney CD, Pinto LA. The SeroNet Clinical and Translational Serology Task Force (CTTF) SARS-CoV-2 mucosal immunity methodological considerations and best practices workshop. Human Vaccines & Immunotherapeutics. 19: 2253598. PMID 37695268 DOI: 10.1080/21645515.2023.2253598  0.375
2023 Rudolph MJ, Davis SA, Haque HME, Ejemel M, Cavacini LA, Vance DJ, Willsey GG, Piazza CL, Weis DD, Wang Y, Mantis NJ. Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi. Proteins. PMID 37455569 DOI: 10.1002/prot.26549  0.446
2023 Bajoria S, Kumru OS, Doering J, Berman K, Slyke GV, Prigodich A, Rodriguez-Aponte SA, Kleanthous H, Love JC, Mantis NJ, Joshi SB, Volkin DB. Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018 Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen. Vaccines. 11. PMID 37376419 DOI: 10.3390/vaccines11061030  0.373
2023 Rudolph MJ, Davis SA, Haque HME, Weis DD, Vance DJ, Piazza CL, Ejemel M, Cavacini L, Wang Y, Mbow ML, Gilmore RD, Mantis NJ. Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. Mbio. e0298122. PMID 36976016 DOI: 10.1128/mbio.02981-22  0.397
2022 Roy CJ, Ehrbar D, Van Slyke G, Doering J, Didier PJ, Doyle-Meyers L, Donini O, Vitetta ES, Mantis NJ. Serum antibody profiling identifies vaccine-induced correlates of protection against aerosolized ricin toxin in rhesus macaques. Npj Vaccines. 7: 164. PMID 36526642 DOI: 10.1038/s41541-022-00582-x  0.46
2022 Haque HME, Ejemel M, Vance DJ, Willsey G, Rudolph MJ, Cavacini LA, Wang Y, Mantis NJ, Weis DD. Human B Cell Epitope Map of the Lyme Disease Vaccine Antigen, OspA. Acs Infectious Diseases. PMID 36350351 DOI: 10.1021/acsinfecdis.2c00346  0.496
2022 Frye AM, Ejemel M, Cavacini L, Wang Y, Rudolph MJ, Song R, Mantis NJ. Agglutination of Borreliella burgdorferi by Transmission-Blocking OspA Monoclonal Antibodies and Monovalent Fab Fragments. Infection and Immunity. e0030622. PMID 36000876 DOI: 10.1128/iai.00306-22  0.43
2022 Movahed E, Vance DJ, Ehrbar D, Van Slyke G, Yates J, Kullas K, Rudolph M, Mantis NJ. Serological Analysis Identifies Consequential B Cell Epitopes on the Flexible Linker and C-Terminus of Decorin Binding Protein A (DbpA) from Borrelia burgdorferi. Msphere. e0025222. PMID 35876530 DOI: 10.1128/msphere.00252-22  0.425
2022 Tolman LE, Yates JL, Rong Y, Reynolds-Peterson C, Ehrbar D, Torres-Velez FJ, Mantis NJ. Durable Immunity to Ricin Toxin Elicited by Intranasally Administered Monoclonal Antibody-Based Immune Complexes. Immunohorizons. 6: 324-333. PMID 35697476 DOI: 10.4049/immunohorizons.2100105  0.406
2022 Bajoria S, Kaur K, Kumru OS, Van Slyke G, Doering J, Novak H, Rodriguez Aponte SA, Dalvie NC, Naranjo CA, Johnston RS, Silverman JM, Kleanthous H, Love JC, Mantis NJ, Joshi SB, et al. Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants. Human Vaccines & Immunotherapeutics. 2079346. PMID 35666264 DOI: 10.1080/21645515.2022.2079346  0.46
2022 Costello CM, Willsey GG, Richards AF, Kim J, Pizzuto MS, Jaconi S, Benigni F, Corti D, Mantis NJ, March JC. Transcytosis of IgA Attenuates Salmonella Invasion in Human Enteroids and Intestinal Organoids. Infection and Immunity. e0004122. PMID 35579465 DOI: 10.1128/iai.00041-22  0.421
2022 Kozlowski PA, Mantis NJ, Frey A. Editorial: Mucosal Vaccination: Strategies to Induce and Evaluate Mucosal Immunity. Frontiers in Immunology. 13: 905150. PMID 35572599 DOI: 10.3389/fimmu.2022.905150  0.311
2022 Czajka TF, Vance DJ, Davis S, Rudolph MJ, Mantis NJ. Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P stalk proteins. The Journal of Biological Chemistry. 101742. PMID 35182523 DOI: 10.1016/j.jbc.2022.101742  0.333
2022 Czajka TF, Mantis NJ. Single-Domain Antibodies for Intracellular Toxin Neutralization. Methods in Molecular Biology (Clifton, N.J.). 2446: 469-487. PMID 35157289 DOI: 10.1007/978-1-0716-2075-5_24  0.468
2022 Doering J, Van Slyke G, Donini O, Mantis NJ. Estimating Vaccine Potency Using Antibody-Based Competition Assays. Methods in Molecular Biology (Clifton, N.J.). 2410: 693-705. PMID 34914076 DOI: 10.1007/978-1-0716-1884-4_37  0.354
2022 Richards AF, Torres-Velez FJ, Mantis NJ. Salmonella Uptake into Gut-Associated Lymphoid Tissues: Implications for Targeted Mucosal Vaccine Design and Delivery. Methods in Molecular Biology (Clifton, N.J.). 2410: 305-324. PMID 34914054 DOI: 10.1007/978-1-0716-1884-4_15  0.349
2021 Dulal HP, Vance DJ, Neupane DP, Chen X, Tremblay JM, Shoemaker CB, Mantis NJ, Song J. Neutralization of typhoid toxin by alpaca-derived, single-domain antibodies targeting the PltB and CdtB subunits. Infection and Immunity. IAI0051521. PMID 34898253 DOI: 10.1128/IAI.00515-21  0.537
2021 Novak H, Doering J, Ehrbar D, Donini O, Mantis NJ. Durable Immunity to Ricin Toxin Elicited by a Thermostable, Lyophilized Subunit Vaccine. Msphere. 6: e0075021. PMID 34730377 DOI: 10.1128/mSphere.00750-21  0.414
2021 Nguyen T, Richards AF, Neupane DP, Feathers JR, Yang YA, Sim JH, Byun H, Lee S, Ahn C, Van Slyke G, Fromme JC, Mantis NJ, Song J. The structural basis of Salmonella AB toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Reports. 36: 109654. PMID 34496256 DOI: 10.1016/j.celrep.2021.109654  0.477
2021 Richards A, Baranova D, Mantis NJ. The prospect of orally administered monoclonal secretory IgA (SIgA) antibodies to prevent enteric bacterial infections. Human Vaccines & Immunotherapeutics. 1-8. PMID 34491878 DOI: 10.1080/21645515.2021.1964317  0.455
2021 Yates JL, Ehrbar DJ, Hunt DT, Girardin RC, Dupuis AP, Payne AF, Sowizral M, Varney S, Kulas KE, Demarest VL, Howard KM, Carson K, Hales M, Ejemel M, Li Q, ... ... Mantis NJ, et al. Serological Analysis Reveals an Imbalanced IgG Subclass Composition Associated with COVID-19 Disease Severity. Cell Reports. Medicine. 100329. PMID 34151306 DOI: 10.1016/j.xcrm.2021.100329  0.399
2021 Ahn C, Yang YA, Neupane DP, Nguyen T, Richards AF, Sim JH, Mantis NJ, Song J. Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits. Iscience. 24: 102454. PMID 34113815 DOI: 10.1016/j.isci.2021.102454  0.361
2021 Rudolph MJ, Poon AY, Kavaliauskiene S, Grethe Myrann A, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ. Structural analysis of toxin-neutralizing, single-domain antibodies that bridge ricin's A-B subunit interface. Journal of Molecular Biology. 167086. PMID 34089718 DOI: 10.1016/j.jmb.2021.167086  0.454
2021 Schiller ZA, Rudolph MJ, Toomey JR, Ejemel M, LaRochelle A, Davis SA, Lambert HS, Kern A, Tardo AC, Souders CA, Peterson E, Cannon RD, Ganesa C, Fazio F, Mantis NJ, et al. Blocking Borrelia burgdorferi transmission from infected ticks to non-human primates with a human monoclonal antibody. The Journal of Clinical Investigation. PMID 33914704 DOI: 10.1172/JCI144843  0.388
2021 Richards AF, Baranova DE, Pizzuto MS, Jaconi S, Willsey GG, Torres-Velez FJ, Doering JE, Benigni F, Corti D, Mantis NJ. Recombinant Human Secretory IgA Induces Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues. Acs Infectious Diseases. PMID 33728898 DOI: 10.1021/acsinfecdis.0c00842  0.387
2020 Baranova DE, Chen L, Destrempes M, Meade H, Mantis NJ. Passive Immunity to O1 Afforded by a Human Monoclonal IgA1 Antibody Expressed in Milk. Pathogens & Immunity. 5: 89-116. PMID 34136728 DOI: 10.20411/pai.v5i1.370  0.468
2020 Roy CJ, Van Slyke G, Ehrbar D, Bornholdt ZA, Brennan MB, Campbell L, Chen M, Kim D, Mlakar N, Whaley KJ, Froude JW, Torres-Velez FJ, Vitetta E, Didier PJ, Doyle-Meyers L, ... ... Mantis NJ, et al. Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin. Npj Vaccines. 5: 13. PMID 33574313 DOI: 10.1038/s41541-020-0162-0  0.407
2020 Czajka TF, Vance DJ, Mantis NJ. Slaying SARS-CoV-2 One (Single-domain) Antibody at a Time. Trends in Microbiology. PMID 33446406 DOI: 10.1016/j.tim.2020.12.006  0.411
2020 Vance DJ, Poon AY, Mantis NJ. Sites of vulnerability on ricin B chain revealed through epitope mapping of toxin-neutralizing monoclonal antibodies. Plos One. 15: e0236538. PMID 33166282 DOI: 10.1371/journal.pone.0236538  0.405
2020 Doering J, Czajka T, Yates JL, Donini O, Mantis NJ. Potency determination of ricin toxin using a monoclonal antibody-based competition assay. Journal of Immunological Methods. 112844. PMID 32891616 DOI: 10.1016/j.jim.2020.112844  0.49
2020 Slyke GV, Ehrbar DJ, Doering J, Yates JL, Vitetta ES, Donini O, Mantis NJ. Endpoint and epitope-specific antibody responses as correlates of vaccine-mediated protection of mice against ricin toxin. Vaccine. PMID 32891474 DOI: 10.1016/j.vaccine.2020.08.047  0.462
2020 Baranova DE, Willsey GG, Levinson KJ, Smith C, Wade J, Mantis NJ. Transcriptional Profiling of Vibrio cholerae O1 following Exposure to Human Anti- Lipopolysaccharide Monoclonal Antibodies. Pathogens and Disease. PMID 32589220 DOI: 10.1093/femspd/ftaa029  0.394
2020 Rong Y, Pauly M, Guthals A, Pham H, Ehrbar D, Zeitlin L, Mantis NJ. A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication. Toxins. 12. PMID 32235318 DOI: 10.3390/toxins12040215  0.44
2020 Richards AF, Doering JE, Lozito SA, Varrone JJ, Willsey GG, Pauly M, Whaley K, Zeitlin L, Mantis NJ. Inhibition of Invasive Salmonella by Orally Administered IgA and IgG Monoclonal Antibodies. Plos Neglected Tropical Diseases. 14: e0007803. PMID 32203503 DOI: 10.1371/journal.pntd.0007803  0.448
2020 Roy CJ, Van Slyke G, Ehrbar D, Bornholdt ZA, Brennan MB, Campbell L, Chen M, Kim D, Mlakar N, Whaley KJ, Froude JW, Torres-Velez FJ, Vitetta E, Didier PJ, Doyle-Meyers L, ... ... Mantis NJ, et al. Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin. Npj Vaccines. 5: 13. PMID 32128254 DOI: 10.1038/s41541-020-0162-0  0.407
2020 Marcinkiewicz AL, Lieknina I, Yang X, Lederman PL, Hart TM, Yates J, Chen WH, Bottazzi ME, Mantis NJ, Kraiczy P, Pal U, Tars K, Lin YP. The Factor H-binding site of CspZ as a protective target against multi-strain, tick-transmitted Lyme disease. Infection and Immunity. PMID 32122944 DOI: 10.1128/Iai.00956-19  0.407
2020 Rudolph MJ, Czajka TF, Davis SA, Thi Nguyen CM, Li XP, Tumer NE, Vance DJ, Mantis NJ. Intracellular Neutralization of Ricin Toxin by Single Domain Antibodies Targeting the Active Site. Journal of Molecular Biology. PMID 31931008 DOI: 10.1016/J.Jmb.2020.01.006  0.429
2020 Baranova DE, Chen L, Destrempes M, Meade H, Mantis NJ. Passive Immunity to Vibrio cholerae O1 Afforded by a Human Monoclonal IgA1 Antibody Expressed in Milk Pathogens and Immunity. 5: 89. DOI: 10.20411/pai.v5i1.370  0.453
2019 Rong Y, Torres-Velez FJ, Ehrbar D, Doering J, Song R, Mantis NJ. An Intranasally Administered Monoclonal Antibody Cocktail Abrogates Ricin Toxin-Induced Pulmonary Tissue Damage and Inflammation. Human Vaccines & Immunotherapeutics. PMID 31589555 DOI: 10.1080/21645515.2019.1664243  0.336
2018 Angalakurthi SK, Vance DJ, Rong Y, Nguyen CMT, Rudolph MJ, Volkin D, Middaugh CR, Weis DD, Mantis NJ. A Collection of Single-Domain Antibodies that Crowd Ricin Toxin's Active Site. Antibodies (Basel, Switzerland). 7. PMID 30775035 DOI: 10.3390/Antib7040045  0.39
2018 Van Slyke G, Angalakurthi SK, Toth RT, Vance DJ, Rong Y, Ehrbar D, Shi Y, Middaugh CR, Volkin DB, Weis DD, Mantis NJ. Fine-Specificity Epitope Analysis Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies. Immunohorizons. 2: 262-273. PMID 30766971 DOI: 10.4049/immunohorizons.1800042  0.351
2018 Rudolph MJ, Vance DJ, Kelow S, Angalakurthi SK, Nguyen S, Davis SA, Rong Y, Middaugh CR, Weis DD, Dunbrack R, Karanicolas J, Mantis NJ. Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. Protein Engineering, Design & Selection : Peds. PMID 30265352 DOI: 10.2210/Pdb6Cwk/Pdb  0.367
2018 Westfall J, Yates JL, Van Slyke G, Ehrbar D, Measey T, Straube R, Donini O, Mantis NJ. Thermal stability and epitope integrity of a lyophilized ricin toxin subunit vaccine. Vaccine. PMID 30172637 DOI: 10.1016/j.vaccine.2018.08.059  0.362
2018 Wei Y, Kumar P, Wahome N, Mantis NJ, Middaugh CR. Biomedical Applications of Lumazine Synthase. Journal of Pharmaceutical Sciences. PMID 29763607 DOI: 10.1016/j.xphs.2018.05.002  0.332
2018 Yates JL, Leadbetter E, Mantis NJ. Alpha-galactosylceramide (αGalCer) Enhances Vaccine-induced Protection in a Model of Ricin Intoxication. Human Vaccines & Immunotherapeutics. 1-14. PMID 29617191 DOI: 10.1080/21645515.2018.1461299  0.379
2018 Baranova DE, Levinson KJ, Mantis NJ. Vibrio cholerae O1 secretes an extracellular matrix in response to antibody-mediated agglutination. Plos One. 13: e0190026. PMID 29293563 DOI: 10.1371/journal.pone.0190026  0.398
2017 Poon AY, Vance DJ, Rong Y, Ehrbar D, Mantis NJ. A Supercluster of Neutralizing Epitopes at the Interface of Ricin's Enzymatic (RTA) and Binding (RTB) Subunits. Toxins. 9. PMID 29168727 DOI: 10.3390/Toxins9120378  0.502
2017 Toth R, Angalakurthi SK, Van Slyke G, Vance DJ, Hickey JM, Joshi SB, Middaugh CR, Volkin DB, Weis DD, Mantis NJ. High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine. Clinical and Vaccine Immunology : Cvi. PMID 29046307 DOI: 10.1128/Cvi.00237-17  0.43
2017 Vance DJ, Tremblay JM, Rong Y, Angalakurthi SK, Volkin DB, Middaugh CR, Weis DD, Shoemaker CB, Mantis NJ. High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Non-Neutralizing Single Domain Antibodies on Ricin Toxin's Enzymatic and Binding Subunits. Clinical and Vaccine Immunology : Cvi. PMID 29021300 DOI: 10.1128/Cvi.00236-17  0.53
2017 Wei Y, Wahome N, VanSlyke G, Whitaker N, Kumar P, Barta ML, Picking WL, Volkin DB, Mantis NJ, Middaugh CR. Evaluation of Lumazine Synthase from Bacillus anthracis as a Presentation Platform for Polyvalent Antigen Display. Protein Science : a Publication of the Protein Society. PMID 28736824 DOI: 10.1002/Pro.3243  0.467
2017 Bazzoli A, Vance DJ, Rudolph MJ, Rong Y, Angalakurthi SK, Toth RT, Middaugh CR, Volkin DB, Weis DD, Karanicolas J, Mantis NJ. Using Homology Modeling to Interrogate Binding Affinity in Neutralization of Ricin Toxin by a Family of Single Domain Antibodies. Proteins. PMID 28718923 DOI: 10.1002/Prot.25353  0.434
2017 Rong Y, Van Slyke G, Vance DJ, Westfall J, Ehrbar D, Mantis NJ. Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin's binding subunit. Plos One. 12: e0180999. PMID 28700745 DOI: 10.1371/Journal.Pone.0180999  0.472
2016 Rudolph MJ, Vance DJ, Cassidy MS, Rong Y, Mantis NJ. Structural analysis of single domain antibodies bound to a second neutralizing hot spot on ricin toxin's enzymatic subunit. The Journal of Biological Chemistry. PMID 27903650 DOI: 10.1074/Jbc.M116.758102  0.425
2016 Levinson KJ, Baranova DE, Mantis NJ. A monoclonal antibody that targets the conserved core/lipid A region of lipopolysaccharide affects motility and reduces intestinal colonization of both classical and El Tor Vibrio cholerae biotypes. Vaccine. PMID 27773473 DOI: 10.1016/j.vaccine.2016.10.023  0.397
2016 Van Slyke G, Sully EK, Bohorova N, Bohorov O, Kim D, Pauly M, Whaley K, Zeitlin L, Mantis NJ. A Humanized Monoclonal Antibody that Passively Protects Mice against Systemic and Intranasal Ricin Toxin Challenge. Clinical and Vaccine Immunology : Cvi. PMID 27466351 DOI: 10.1128/CVI.00088-16  0.491
2016 Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ. A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking. Plos One. 11: e0156893. PMID 27300140 DOI: 10.1371/journal.pone.0156893  0.454
2016 Greene CJ, Hu JC, Vance DJ, Rong Y, Mandell L, King-Lyons N, Masso-Welch P, Mantis NJ, Connell TD. Enhancement of humoral immunity by the type II heat-labile enterotoxin LT-IIb is dependent upon IL-6 and neutrophils. Journal of Leukocyte Biology. PMID 27059843 DOI: 10.1189/Jlb.3A0415-153Rr  0.374
2016 Vance DJ, Mantis NJ. Progress and Challenges Associated with the Development of Ricin Toxin Subunit Vaccines. Expert Review of Vaccines. PMID 26998662 DOI: 10.1586/14760584.2016.1168701  0.463
2016 Wahome N, Sully E, Singer C, Thomas JC, Hu L, Joshi SB, Volkin DB, Fang J, Karanicolas J, Jacobs DJ, Mantis NJ, Middaugh CR. Novel Ricin Subunit Antigens With Enhanced Capacity to Elicit Toxin-Neutralizing Antibody Responses in Mice. Journal of Pharmaceutical Sciences. PMID 26987947 DOI: 10.1016/J.Xphs.2016.02.009  0.544
2016 Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ. Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport. Scientific Reports. 6: 22721. PMID 26949061 DOI: 10.1038/Srep22721  0.778
2016 Brey RN, Mantis NJ, Pincus SH, Vitetta ES, Smith LA, Roy CJ. Recent Advances in the Development of Vaccines against Ricin. Human Vaccines & Immunotherapeutics. 0. PMID 26810367 DOI: 10.1080/21645515.2015.1124202  0.401
2015 Vance DJ, Greene CJ, Rong Y, Mandell LM, Connell TD, Mantis NJ. Comparative Adjuvant Effects of Type II Heat-Labile Enterotoxins in Combination with Two Different Candidate Ricin Toxin Vaccine Antigens. Clinical and Vaccine Immunology : Cvi. PMID 26491037 DOI: 10.1128/Cvi.00402-15  0.5
2015 Herrera C, Tremblay JM, Shoemaker CB, Mantis NJ. Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies. The Journal of Biological Chemistry. PMID 26396190 DOI: 10.1074/jbc.M115.658070  0.512
2015 Levinson KJ, Giffen SR, Pauly MH, Kim do H, Bohorov O, Bohorova N, Whaley KJ, Zeitlin L, Mantis NJ. Plant-based production of two chimeric monoclonal IgG antibodies directed against immunodominant epitopes of Vibrio cholerae lipopolysaccharide. Journal of Immunological Methods. 422: 111-7. PMID 25865265 DOI: 10.1016/j.jim.2015.04.001  0.503
2015 Roy CJ, Brey RN, Mantis NJ, Mapes K, Pop IV, Pop LM, Ruback S, Killeen SZ, Doyle-Meyers L, Vinet-Oliphant HS, Didier PJ, Vitetta ES. Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection. Proceedings of the National Academy of Sciences of the United States of America. 112: 3782-7. PMID 25775591 DOI: 10.1073/pnas.1502585112  0.555
2015 Levinson KJ, De Jesus M, Mantis NJ. Rapid effects of a protective O-polysaccharide-specific monoclonal IgA on Vibrio cholerae agglutination, motility, and surface morphology. Infection and Immunity. 83: 1674-83. PMID 25667263 DOI: 10.1128/IAI.02856-14  0.345
2015 Hassett KJ, Vance DJ, Jain NK, Sahni N, Rabia LA, Cousins MC, Joshi S, Volkin DB, Middaugh CR, Mantis NJ, Carpenter JF, Randolph TW. Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants. Journal of Pharmaceutical Sciences. 104: 627-39. PMID 25581103 DOI: 10.1002/Jps.24295  0.325
2015 Vance DJ, Rong Y, Brey RN, Mantis NJ. Combination of two candidate subunit vaccine antigens elicits protective immunity to ricin and anthrax toxin in mice. Vaccine. 33: 417-21. PMID 25475957 DOI: 10.1016/J.Vaccine.2014.11.036  0.528
2015 Mukherjee J, Tremblay J, Sheoran A, Schmidt D, Vance DJ, Mantis NJ, Moayeri M, Leppla SH, Dmitriev I, Curiel DT, Tzipori S, Shoemaker CB. 148. Variable fragment of heavy chain antibody (VHH)–based neutralizing agents (VNAs) as unconventional and versatile therapeutics for toxin-mediated diseases Toxicon. 93: S46. DOI: 10.1016/J.Toxicon.2014.11.151  0.355
2014 Sully EK, Whaley K, Bohorova N, Bohorov O, Goodman C, Kim D, Pauly M, Velasco J, Holtsberg FW, Stavale E, Aman MJ, Tangudu C, Uzal FA, Mantis NJ, Zeitlin L. A tripartite cocktail of chimeric monoclonal antibodies passively protects mice against ricin, staphylococcal enterotoxin B and Clostridium perfringens epsilon toxin. Toxicon : Official Journal of the International Society On Toxinology. 92: 36-41. PMID 25260254 DOI: 10.1016/j.toxicon.2014.09.006  0.47
2014 Herrera C, Vance DJ, Eisele LE, Shoemaker CB, Mantis NJ. Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB). Plos One. 9: e99788. PMID 24918772 DOI: 10.1371/Journal.Pone.0099788  0.491
2014 Rudolph MJ, Vance DJ, Cheung J, Franklin MC, Burshteyn F, Cassidy MS, Gary EN, Herrera C, Shoemaker CB, Mantis NJ. Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies. Journal of Molecular Biology. 426: 3057-68. PMID 24907552 DOI: 10.1016/J.Jmb.2014.05.026  0.45
2014 Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ. Antibody-mediated inhibition of ricin toxin retrograde transport. Mbio. 5: e00995. PMID 24713323 DOI: 10.1128/Mbio.00995-13  0.837
2014 Sully EK, Whaley KJ, Bohorova N, Bohorov O, Goodman C, Kim do H, Pauly MH, Velasco J, Hiatt E, Morton J, Swope K, Roy CJ, Zeitlin L, Mantis NJ. Chimeric plantibody passively protects mice against aerosolized ricin challenge. Clinical and Vaccine Immunology : Cvi. 21: 777-82. PMID 24574537 DOI: 10.1128/CVI.00003-14  0.39
2014 O'Hara JM, Kasten-Jolly JC, Reynolds CE, Mantis NJ. Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA). Immunology Letters. 158: 7-13. PMID 24269767 DOI: 10.1016/j.imlet.2013.11.009  0.806
2014 Sully EK, Whaley K, Bohorova N, Bohorov O, Goodman C, Kim D, Pauly M, Velasco J, Holtsberg FW, Stavale E, Aman MJ, Tangudu C, Uzal FA, Mantis NJ, Zeitlin L. A tripartite cocktail of chimeric monoclonal antibodies passively protects mice against ricin, staphylococcal enterotoxin B and Clostridium perfringens epsilon toxin Toxicon. 92: 36-41. DOI: 10.1016/j.toxicon.2014.09.006  0.48
2013 Vance DJ, Tremblay JM, Mantis NJ, Shoemaker CB. Stepwise engineering of heterodimeric single domain camelid VHH antibodies that passively protect mice from ricin toxin. The Journal of Biological Chemistry. 288: 36538-47. PMID 24202178 DOI: 10.1074/Jbc.M113.519207  0.492
2013 Greene CJ, Chadwick CM, Mandell LM, Hu JC, O'Hara JM, Brey RN, Mantis NJ, Connell TD. LT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunity. Plos One. 8: e69678. PMID 23936344 DOI: 10.1371/Journal.Pone.0069678  0.788
2013 Iyer V, Hu L, Schanté CE, Vance D, Chadwick C, Jain NK, Brey RN, Joshi SB, Volkin DB, Andra KK, Bann JG, Mantis NJ, Middaugh CR. Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine. Human Vaccines & Immunotherapeutics. 9: 2362-70. PMID 23925275 DOI: 10.4161/Hv.25852  0.335
2013 O'Hara JM, Mantis NJ. Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro. Journal of Immunological Methods. 395: 71-8. PMID 23774033 DOI: 10.1016/J.Jim.2013.06.004  0.805
2013 Yermakova A, Mantis NJ. Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragments. Toxicon : Official Journal of the International Society On Toxinology. 72: 29-34. PMID 23603317 DOI: 10.1016/J.Toxicon.2013.04.005  0.83
2013 Hassett KJ, Cousins MC, Rabia LA, Chadwick CM, O'Hara JM, Nandi P, Brey RN, Mantis NJ, Carpenter JF, Randolph TW. Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 85: 279-86. PMID 23583494 DOI: 10.1016/J.Ejpb.2013.03.029  0.775
2013 Thomas JC, O'Hara JM, Hu L, Gao FP, Joshi SB, Volkin DB, Brey RN, Fang J, Karanicolas J, Mantis NJ, Middaugh CR. Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Human Vaccines & Immunotherapeutics. 9: 744-52. PMID 23563512 DOI: 10.4161/Hv.22998  0.802
2013 O'Hara JM, Brey RN, Mantis NJ. Comparative efficacy of two leading candidate ricin toxin a subunit vaccines in mice. Clinical and Vaccine Immunology : Cvi. 20: 789-94. PMID 23515013 DOI: 10.1128/Cvi.00098-13  0.796
2012 Stringer AM, Singh N, Yermakova A, Petrone BL, Amarasinghe JJ, Reyes-Diaz L, Mantis NJ, Wade JT. FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica. Plos One. 7: e44841. PMID 23028641 DOI: 10.1371/Journal.Pone.0044841  0.741
2012 Yermakova A, Vance DJ, Mantis NJ. Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies. Plos One. 7: e44317. PMID 22984492 DOI: 10.1371/Journal.Pone.0044317  0.799
2012 Vance DJ, Mantis NJ. Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit. Toxicon : Official Journal of the International Society On Toxinology. 60: 874-7. PMID 22750533 DOI: 10.1016/J.Toxicon.2012.06.014  0.453
2012 Forbes SJ, Martinelli D, Hsieh C, Ault JG, Marko M, Mannella CA, Mantis NJ. Association of a protective monoclonal IgA with the O antigen of Salmonella enterica serovar Typhimurium impacts type 3 secretion and outer membrane integrity. Infection and Immunity. 80: 2454-63. PMID 22473607 DOI: 10.1128/Iai.00018-12  0.636
2012 O'Hara JM, Whaley K, Pauly M, Zeitlin L, Mantis NJ. Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit. Vaccine. 30: 1239-43. PMID 22197964 DOI: 10.1016/j.vaccine.2011.12.058  0.79
2012 O'Hara JM, Yermakova A, Mantis NJ. Immunity to ricin: fundamental insights into toxin-antibody interactions. Current Topics in Microbiology and Immunology. 357: 209-41. PMID 22113742 DOI: 10.1007/82_2011_193  0.806
2012 Mantis NJ. Rediscovering IgA. Mucosal Immunology. 4: 588-9. PMID 22005880 DOI: 10.1038/mi.2011.42  0.342
2011 Gage E, Hernandez MO, O'Hara JM, McCarthy EA, Mantis NJ. Role of the mannose receptor (CD206) in innate immunity to ricin toxin. Toxins. 3: 1131-45. PMID 22069759 DOI: 10.3390/toxins3091131  0.72
2011 Mantis NJ, Rol N, Corthésy B. Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunology. 4: 603-11. PMID 21975936 DOI: 10.1038/mi.2011.41  0.322
2011 Yermakova A, Mantis NJ. Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB). Vaccine. 29: 7925-35. PMID 21872634 DOI: 10.1016/J.Vaccine.2011.08.075  0.847
2011 Forbes SJ, Bumpus T, McCarthy EA, Corthésy B, Mantis NJ. Transient suppression of Shigella flexneri type 3 secretion by a protective O-antigen-specific monoclonal IgA. Mbio. 2: e00042-11. PMID 21610121 DOI: 10.1128/Mbio.00042-11  0.658
2011 Neal LM, McCarthy EA, Morris CR, Mantis NJ. Vaccine-induced intestinal immunity to ricin toxin in the absence of secretory IgA. Vaccine. 29: 681-9. PMID 21115050 DOI: 10.1016/J.Vaccine.2010.11.030  0.519
2010 O'Hara JM, Neal LM, McCarthy EA, Kasten-Jolly JA, Brey RN, Mantis NJ. Folding domains within the ricin toxin A subunit as targets of protective antibodies. Vaccine. 28: 7035-46. PMID 20727394 DOI: 10.1016/J.Vaccine.2010.08.020  0.816
2010 Mantis NJ, Forbes SJ. Secretory IgA: arresting microbial pathogens at epithelial borders. Immunological Investigations. 39: 383-406. PMID 20450284 DOI: 10.3109/08820131003622635  0.644
2010 Neal LM, O'Hara J, Brey RN, Mantis NJ. A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin. Infection and Immunity. 78: 552-61. PMID 19858297 DOI: 10.1128/Iai.00796-09  0.828
2009 Kelly-Cirino CD, Mantis NJ. Neutralizing monoclonal antibodies directed against defined linear epitopes on domain 4 of anthrax protective antigen. Infection and Immunity. 77: 4859-67. PMID 19703971 DOI: 10.1128/Iai.00117-09  0.807
2008 Forbes SJ, Eschmann M, Mantis NJ. Inhibition of Salmonella enterica serovar typhimurium motility and entry into epithelial cells by a protective antilipopolysaccharide monoclonal immunoglobulin A antibody. Infection and Immunity. 76: 4137-44. PMID 18625740 DOI: 10.1128/Iai.00416-08  0.718
2007 Mantis NJ, Palaia J, Hessell AJ, Mehta S, Zhu Z, Corthésy B, Neutra MR, Burton DR, Janoff EN. Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region. Journal of Immunology (Baltimore, Md. : 1950). 179: 3144-52. PMID 17709529 DOI: 10.4049/Jimmunol.179.5.3144  0.304
2007 Yoder JM, Aslam RU, Mantis NJ. Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication. Infection and Immunity. 75: 1745-50. PMID 17283086 DOI: 10.1128/IAI.01528-06  0.321
2006 McGuinness CR, Mantis NJ. Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit. Infection and Immunity. 74: 3463-70. PMID 16714577 DOI: 10.1128/IAI.00324-06  0.429
2006 Mantis NJ, McGuinness CR, Sonuyi O, Edwards G, Farrant SA. Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication. Infection and Immunity. 74: 3455-62. PMID 16714576 DOI: 10.1128/IAI.02088-05  0.487
2004 Mantis NJ, Farrant SA, Mehta S. Oligosaccharide side chains on human secretory IgA serve as receptors for ricin. Journal of Immunology (Baltimore, Md. : 1950). 172: 6838-45. PMID 15153502  0.383
2001 Neutra MR, Mantis NJ, Kraehenbuhl JP. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nature Immunology. 2: 1004-9. PMID 11685223 DOI: 10.1038/ni1101-1004  0.302
2001 Mantis NJ, Kozlowski PA, Mielcarz DW, Weissenhorn W, Neutra MR. Immunization of mice with recombinant gp41 in a systemic prime/mucosal boost protocol induces HIV-1-specific serum IgG and secretory IgA antibodies. Vaccine. 19: 3990-4001. PMID 11427275 DOI: 10.1016/S0264-410X(01)00115-3  0.351
1999 Frey A, Mantis N, Kozlowski PA, Quayle AJ, Bajardi A, Perdomo JJ, Robey FA, Neutra MR. Immunization of mice with peptomers covalently coupled to aluminum oxide nanoparticles. Vaccine. 17: 3007-3019. PMID 10462236 DOI: 10.1016/S0264-410X(99)00163-2  0.522
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