| Year |
Citation |
Score |
| 2023 |
Webb JA, Farrow E, Cain B, Yuan Z, Yarawsky AE, Schoch E, Gagliani EK, Herr AB, Gebelein B, Kovall RA. Cooperative Gsx2-DNA Binding Requires DNA Bending and a Novel Gsx2 Homeodomain Interface. Biorxiv : the Preprint Server For Biology. PMID 38106145 DOI: 10.1101/2023.12.08.570805 |
0.43 |
|
| 2023 |
Cain B, Webb J, Yuan Z, Cheung D, Lim HW, Kovall RA, Weirauch MT, Gebelein B. Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data. Nucleic Acids Research. PMID 37114997 DOI: 10.1093/nar/gkad318 |
0.411 |
|
| 2023 |
Diluvio G, Kelley TT, Lahiry M, Alvarez-Trotta A, Kolb EM, Shersher E, Astudillo L, Kovall RA, Schürer SC, Capobianco AJ. A novel chemical attack on Notch-mediated transcription by targeting the NACK ATPase. Molecular Therapy Oncolytics. 28: 307-320. PMID 36938545 DOI: 10.1016/j.omto.2023.02.008 |
0.43 |
|
| 2023 |
Maier D, Bauer M, Boger M, Sanchez Jimenez A, Yuan Z, Fechner J, Scharpf J, Kovall RA, Preiss A, Nagel AC. Genetic and Molecular Interactions between , a Novel Allele of the Notch Antagonist Hairless, and the Histone Chaperone Asf1 in . Genes. 14. PMID 36672946 DOI: 10.3390/genes14010205 |
0.486 |
|
| 2022 |
Hall D, Giaimo BD, Park SS, Hemmer W, Friedrich T, Ferrante F, Bartkuhn M, Yuan Z, Oswald F, Borggrefe T, Rual JF, Kovall RA. The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3. Nucleic Acids Research. PMID 36477367 DOI: 10.1093/nar/gkac1137 |
0.606 |
|
| 2022 |
Gagliani EK, Gutzwiller LM, Kuang Y, Odaka Y, Hoffmeister P, Hauff S, Turkiewicz A, Harding-Theobald E, Dolph PJ, Borggrefe T, Oswald F, Gebelein B, Kovall RA. A Drosophila Su(H) model of Adams-Oliver Syndrome reveals cofactor titration as a mechanism underlying developmental defects. Plos Genetics. 18: e1010335. PMID 35951645 DOI: 10.1371/journal.pgen.1010335 |
0.381 |
|
| 2021 |
Kuang Y, Pyo A, Eafergan N, Cain B, Gutzwiller LM, Axelrod O, Gagliani EK, Weirauch MT, Kopan R, Kovall RA, Sprinzak D, Gebelein B. Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor. Plos Genetics. 17: e1009039. PMID 34559800 DOI: 10.1371/journal.pgen.1009039 |
0.475 |
|
| 2021 |
Landor SKJ, Santio NM, Eccleshall WB, Paramonov VM, Gagliani EK, Hall D, Jin SB, Dahlström KM, Salminen TA, Rivero-Müller A, Lendahl U, Kovall RA, Koskinen PJ, Sahlgren C. PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion. The Journal of Biological Chemistry. 100593. PMID 33775697 DOI: 10.1016/j.jbc.2021.100593 |
0.358 |
|
| 2021 |
Giaimo BD, Gagliani EK, Kovall RA, Borggrefe T. Transcription Factor RBPJ as a Molecular Switch in Regulating the Notch Response. Advances in Experimental Medicine and Biology. 1287: 9-30. PMID 33034023 DOI: 10.1007/978-3-030-55031-8_2 |
0.52 |
|
| 2020 |
Kobia FM, Preusse K, Dai Q, Weaver N, Hass MR, Chaturvedi P, Stein SJ, Pear WS, Yuan Z, Kovall RA, Kuang Y, Eafergen N, Sprinzak D, Gebelein B, Brunskill EW, et al. Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation. Plos Biology. 18: e3000850. PMID 33017398 DOI: 10.1371/journal.pbio.3000850 |
0.404 |
|
| 2020 |
Kuang Y, Golan O, Preusse K, Cain B, Christensen CJ, Salomone J, Campbell I, Okwubido-Williams FV, Hass MR, Yuan Z, Eafergan N, Moberg KH, Kovall RA, Kopan R, Sprinzak D, et al. Enhancer architecture sensitizes cell-specific responses to gene dose via a bind and discard mechanism. Elife. 9. PMID 32297857 DOI: 10.7554/Elife.53659 |
0.44 |
|
| 2019 |
Hall DP, Kovall RA. Structurally conserved binding motifs of transcriptional regulators to notch nuclear effector CSL. Experimental Biology and Medicine (Maywood, N.J.). 1535370219877818. PMID 31544502 DOI: 10.1177/1535370219877818 |
0.458 |
|
| 2019 |
Zhang X, McGrath PS, Salomone J, Rahal M, McCauley HA, Schweitzer J, Kovall R, Gebelein B, Wells JM. A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development. Developmental Cell. PMID 31178402 DOI: 10.1016/J.Devcel.2019.05.017 |
0.378 |
|
| 2019 |
Yuan Z, VanderWielen BD, Giaimo BD, Pan L, Collins CE, Turkiewicz A, Hein K, Oswald F, Borggrefe T, Kovall RA. Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site. Cell Reports. 26: 845-854.e6. PMID 30673607 DOI: 10.1016/j.celrep.2018.12.097 |
0.571 |
|
| 2019 |
Kolb E, Hall D, Webb J, Kovall R. Structural and mechanistic basis for CBP/P300 recruitment to the Notch transcription complex Acta Crystallographica Section a Foundations and Advances. 75: a239-a239. DOI: 10.1107/S0108767319097642 |
0.443 |
|
| 2018 |
Oswald F, Kovall RA. CSL-Associated Corepressor and Coactivator Complexes. Advances in Experimental Medicine and Biology. 1066: 279-295. PMID 30030832 DOI: 10.1007/978-3-319-89512-3_14 |
0.588 |
|
| 2018 |
Miesfeld JB, Moon MS, Riesenberg AN, Contreras AN, Kovall RA, Brown NL. Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Scientific Reports. 8: 10195. PMID 29977079 DOI: 10.1038/S41598-018-28420-Y |
0.672 |
|
| 2018 |
Gomez-Lamarca MJ, Falo-Sanjuan J, Stojnic R, Abdul Rehman S, Muresan L, Jones ML, Pillidge Z, Cerda-Moya G, Yuan Z, Baloul S, Valenti P, Bystricky K, Payre F, O'Holleran K, Kovall R, et al. Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics. Developmental Cell. PMID 29478922 DOI: 10.1016/J.Devcel.2018.01.020 |
0.533 |
|
| 2017 |
Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, ... ... Kovall RA, et al. RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1. The Embo Journal. PMID 29030483 DOI: 10.15252/Embj.201796525 |
0.532 |
|
| 2017 |
Nagel AC, Auer JS, Schulz A, Pfannstiel J, Yuan Z, Collins CE, Kovall RA, Preiss A. Phosphorylation of Suppressor of Hairless impedes its DNA-binding activity. Scientific Reports. 7: 11820. PMID 28928428 DOI: 10.1038/s41598-017-11952-0 |
0.421 |
|
| 2017 |
Tabaja N, Yuan Z, Oswald F, Kovall RA. Structure-function analysis of RBPJ-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes. The Journal of Biological Chemistry. PMID 28487372 DOI: 10.1074/jbc.M117.791707 |
0.525 |
|
| 2017 |
Kovall RA, Gebelein B, Sprinzak D, Kopan R. The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force. Developmental Cell. 41: 228-241. PMID 28486129 DOI: 10.1016/j.devcel.2017.04.001 |
0.337 |
|
| 2016 |
Yuan Z, Praxenthaler H, Tabaja N, Torella R, Preiss A, Maier D, Kovall RA. Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster. Plos Biology. 14: e1002509. PMID 27404588 DOI: 10.1371/journal.pbio.1002509 |
0.467 |
|
| 2016 |
Oswald F, Rodriguez P, Giaimo BD, Antonello ZA, Mira L, Mittler G, Thiel VN, Collins KJ, Tabaja N, Cizelsky W, Rothe M, Kühl SJ, Kühl M, Ferrante F, Hein K, ... Kovall RA, et al. A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic Acids Research. PMID 26912830 DOI: 10.1093/nar/gkw105 |
0.419 |
|
| 2015 |
Contreras AN, Yuan Z, Kovall RA. Thermodynamic binding analysis of Notch transcription complexes from Drosophila melanogaster. Protein Science : a Publication of the Protein Society. 24: 812-22. PMID 25650119 DOI: 10.1002/Pro.2652 |
0.683 |
|
| 2014 |
Torella R, Li J, Kinrade E, Cerda-Moya G, Contreras AN, Foy R, Stojnic R, Glen RC, Kovall RA, Adryan B, Bray SJ. A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL. Nucleic Acids Research. 42: 10550-63. PMID 25114055 DOI: 10.1093/Nar/Gku730 |
0.667 |
|
| 2014 |
Collins KJ, Yuan Z, Kovall RA. Structure and function of the CSL-KyoT2 corepressor complex: A negative regulator of Notch signaling Structure. 22: 70-81. PMID 24290140 DOI: 10.1016/j.str.2013.10.010 |
0.531 |
|
| 2013 |
Greenwald I, Kovall R. Notch signaling: genetics and structure. Wormbook : the Online Review of C. Elegans Biology. 1-28. PMID 23355521 DOI: 10.1895/Wormbook.1.10.2 |
0.465 |
|
| 2012 |
Yuan Z, Friedmann DR, VanderWielen BD, Collins KJ, Kovall RA. Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2. The Journal of Biological Chemistry. 287: 34904-16. PMID 22915591 DOI: 10.1074/Jbc.M112.403287 |
0.734 |
|
| 2011 |
Kurth P, Preiss A, Kovall RA, Maier D. Molecular analysis of the notch repressor-complex in Drosophila: characterization of potential hairless binding sites on suppressor of hairless. Plos One. 6: e27986. PMID 22125648 DOI: 10.1371/journal.pone.0027986 |
0.538 |
|
| 2011 |
Maier D, Kurth P, Schulz A, Russell A, Yuan Z, Gruber K, Kovall RA, Preiss A. Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster. Molecular Biology of the Cell. 22: 3242-52. PMID 21737682 DOI: 10.1091/mbc.E11-05-0420 |
0.531 |
|
| 2011 |
VanderWielen BD, Yuan Z, Friedmann DR, Kovall RA. Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes. The Journal of Biological Chemistry. 286: 14892-902. PMID 21372128 DOI: 10.1074/Jbc.M110.181156 |
0.757 |
|
| 2011 |
Bahassi el M, Yin M, Robbins SB, Li YQ, Conrady DG, Yuan Z, Kovall RA, Herr AB, Stambrook PJ. A human cancer-predisposing polymorphism in Cdc25A is embryonic lethal in the mouse and promotes ASK-1 mediated apoptosis. Cell Division. 6: 4. PMID 21310058 DOI: 10.1186/1747-1028-6-4 |
0.347 |
|
| 2010 |
Conrady DG, Flagler MJ, Friedmann DR, Vander Wielen BD, Kovall RA, Weiss AA, Herr AB. Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2. Plos One. 5: e15153. PMID 21203383 DOI: 10.1371/Journal.Pone.0015153 |
0.571 |
|
| 2010 |
Kovall RA, Blacklow SC. Mechanistic insights into Notch receptor signaling from structural and biochemical studies. Current Topics in Developmental Biology. 92: 31-71. PMID 20816392 DOI: 10.1016/S0070-2153(10)92002-4 |
0.351 |
|
| 2010 |
Friedmann DR, Kovall RA. Thermodynamic and structural insights into CSL-DNA complexes. Protein Science : a Publication of the Protein Society. 19: 34-46. PMID 19866488 DOI: 10.1002/Pro.280 |
0.739 |
|
| 2008 |
Kovall RA. More complicated than it looks: assembly of Notch pathway transcription complexes. Oncogene. 27: 5099-109. PMID 18758478 DOI: 10.1038/onc.2008.223 |
0.548 |
|
| 2008 |
Friedmann DR, Wilson JJ, Kovall RA. RAM-induced allostery facilitates assembly of a notch pathway active transcription complex. The Journal of Biological Chemistry. 283: 14781-91. PMID 18381292 DOI: 10.1074/Jbc.M709501200 |
0.739 |
|
| 2007 |
Kovall RA. Structures of CSL, Notch and Mastermind proteins: piecing together an active transcription complex. Current Opinion in Structural Biology. 17: 117-27. PMID 17157496 DOI: 10.1016/j.sbi.2006.11.004 |
0.368 |
|
| 2006 |
Wilson JJ, Kovall RA. Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell. 124: 985-96. PMID 16530045 DOI: 10.1016/j.cell.2006.01.035 |
0.567 |
|
| 2004 |
Kovall RA, Hendrickson WA. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA Embo Journal. 23: 3441-3451. PMID 15297877 DOI: 10.1038/Sj.Emboj.7600349 |
0.651 |
|
| 2003 |
Min KC, Kovall RA, Hendrickson WA. Crystal structure of human α-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency Proceedings of the National Academy of Sciences of the United States of America. 100: 14713-14718. PMID 14657365 DOI: 10.1073/Pnas.2136684100 |
0.429 |
|
| 1999 |
Kovall RA, Matthews BW. Type II restriction endonucleases: structural, functional and evolutionary relationships. Current Opinion in Chemical Biology. 3: 578-83. PMID 10508668 DOI: 10.1016/S1367-5931(99)00012-5 |
0.461 |
|
| 1998 |
Kovall RA, Matthews BW. Structural, functional, and evolutionary relationships between lambda-exonuclease and the type II restriction endonucleases. Proceedings of the National Academy of Sciences of the United States of America. 95: 7893-7. PMID 9653111 DOI: 10.1073/Pnas.95.14.7893 |
0.499 |
|
| 1997 |
Kovall R, Matthews BW. Toroidal structure of lambda-exonuclease. Science (New York, N.Y.). 277: 1824-7. PMID 9295273 DOI: 10.1126/Science.277.5333.1824 |
0.522 |
|
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