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Sayaka Shibata, Ph.D. - Publications

Affiliations: 
2011 University of Washington, Seattle, Seattle, WA 
Area:
Biochemistry
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang Z, Barros-Álvarez X, Gillespie JR, Ranade RM, Huang W, Shibata S, Molasky NMR, Faghih O, Mushtaq A, Choy RKM, de Hostos E, Hol WGJ, Verlinde CLMJ, Buckner FS, Fan E. Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against . Rsc Medicinal Chemistry. 11: 885-895. PMID 33479683 DOI: 10.1039/d0md00057d  0.511
2019 Buckner FS, Ranade RM, Gillespie JR, Shibata S, Hulverson MA, Zhang Z, Huang W, Choi R, Verlinde CLMJ, Hol WGJ, Ochida A, Akao Y, Choy RKM, Van Voorhis WC, Arnold SLM, et al. Optimization of methionyl tRNA-synthetase inhibitors for treatment of infection. Antimicrobial Agents and Chemotherapy. PMID 30745384 DOI: 10.1128/Aac.02061-18  0.546
2018 Herbst ZM, Shibata S, Fan E, Gelb MH. An Inexpensive, In-House-Made, Microdialysis Device for Measuring Drug-Protein Binding. Acs Medicinal Chemistry Letters. 9: 279-282. PMID 29541374 DOI: 10.1021/Acsmedchemlett.7B00316  0.487
2017 Faghih O, Zhang Z, Ranade RM, Gillespie JR, Creason SA, Huang W, Shibata S, Barros-Álvarez X, Verlinde CLMJ, Hol WGJ, Fan E, Buckner FS. Development of methionyl-tRNA synthetase inhibitors as antibiotics for Gram-positive bacterial infections. Antimicrobial Agents and Chemotherapy. PMID 28848016 DOI: 10.1128/Aac.00999-17  0.533
2017 Huang W, Zhang Z, Ranade RM, Gillespie JR, Barros-Álvarez X, Creason SA, Shibata S, Verlinde CLMJ, Hol WGJ, Buckner FS, Fan E. Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28465105 DOI: 10.1016/J.Bmcl.2017.04.048  0.548
2016 Huang W, Zhang Z, Barros-Álvarez X, Koh CY, Ranade RM, Gillespie JR, Creason SA, Shibata S, Verlinde CL, Hol WG, Buckner FS, Fan E. Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. European Journal of Medicinal Chemistry. 124: 1081-1092. PMID 27788467 DOI: 10.1016/J.Ejmech.2016.10.024  0.543
2016 Zhang Z, Koh CY, Ranade RM, Shibata S, Gillespie JR, Hulverson MA, Huang W, Nguyen J, Pendem N, Gelb MH, Verlinde CL, Hol WG, Buckner FS, Fan E. 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. Acs Infectious Diseases. 2: 399-404. PMID 27627628 DOI: 10.1021/Acsinfecdis.6B00036  0.541
2015 Hau CS, Kanda N, Tada Y, Shibata S, Uozaki H, Fukusato T, Sato S, Watanabe S. Lipocalin-2 exacerbates psoriasiform skin inflammation by augmenting T-helper 17 response. The Journal of Dermatology. PMID 26702876 DOI: 10.1111/1346-8138.13227  0.311
2015 Ranade RM, Zhang Z, Gillespie JR, Shibata S, Verlinde CL, Hol WG, Fan E, Buckner FS. Inhibitors of methionyl-tRNA synthetase have potent activity against Giardia intestinalis trophozoites. Antimicrobial Agents and Chemotherapy. 59: 7128-31. PMID 26324270 DOI: 10.1128/Aac.01573-15  0.555
2014 Koh CY, Kim JE, Wetzel AB, de van der Schueren WJ, Shibata S, Ranade RM, Liu J, Zhang Z, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG. Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness. Plos Neglected Tropical Diseases. 8: e2775. PMID 24743796 DOI: 10.1371/Journal.Pntd.0002775  0.644
2014 Koh CY, Nguyen J, Shibata S, Zhang Z, Ranade R, Gillespie JR, Hodder P, Pedro-Rosa L, Bannister T, Buckner F, Verlinde C, Fan E, Hol W. Structure-based drug design against Trypanosoma brucei methionyl-tRNA synthetase Acta Crystallographica Section a Foundations and Advances. 70: C708-C708. DOI: 10.1107/S2053273314092912  0.548
2013 Ranade RM, Gillespie JR, Shibata S, Verlinde CL, Fan E, Hol WG, Buckner FS. Induced resistance to methionyl-tRNA synthetase inhibitors in Trypanosoma brucei is due to overexpression of the target. Antimicrobial Agents and Chemotherapy. 57: 3021-8. PMID 23587950 DOI: 10.1128/Aac.02578-12  0.525
2013 Masui Y, Asano Y, Shibata S, Noda S, Akamata K, Aozasa N, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Sumida H, Yanaba K, Tada Y, Sugaya M, Sato S, et al. A possible contribution of visfatin to the resolution of skin sclerosis in patients with diffuse cutaneous systemic sclerosis via a direct anti-fibrotic effect on dermal fibroblasts and Th1 polarization of the immune response. Rheumatology (Oxford, England). 52: 1239-44. PMID 23443327 DOI: 10.1093/Rheumatology/Ket010  0.303
2012 Koh CY, Kim JE, Shibata S, Ranade RM, Yu M, Liu J, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG. Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure (London, England : 1993). 20: 1681-91. PMID 22902861 DOI: 10.1016/J.Str.2012.07.011  0.642
2012 Shibata S, Gillespie JR, Ranade RM, Koh CY, Kim JE, Laydbak JU, Zucker FH, Hol WG, Verlinde CL, Buckner FS, Fan E. Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization. Journal of Medicinal Chemistry. 55: 6342-51. PMID 22720744 DOI: 10.1021/Jm300303E  0.563
2011 Shibata S, Zhang Z, Korotkov KV, Delarosa J, Napuli A, Kelley AM, Mueller N, Ross J, Zucker FH, Buckner FS, Merritt EA, Verlinde CL, Van Voorhis WC, Hol WG, Fan E. Screening a fragment cocktail library using ultrafiltration. Analytical and Bioanalytical Chemistry. 401: 1585-91. PMID 21750879 DOI: 10.1007/S00216-011-5225-7  0.512
2011 Shibata S, Gillespie JR, Kelley AM, Napuli AJ, Zhang Z, Kovzun KV, Pefley RM, Lam J, Zucker FH, Van Voorhis WC, Merritt EA, Hol WG, Verlinde CL, Fan E, Buckner FS. Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice. Antimicrobial Agents and Chemotherapy. 55: 1982-9. PMID 21282428 DOI: 10.1128/Aac.01796-10  0.579
2009 Verlinde CL, Fan E, Shibata S, Zhang Z, Sun Z, Deng W, Ross J, Kim J, Xiao L, Arakaki TL, Bosch J, Caruthers JM, Larson ET, Letrong I, Napuli A, et al. Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium. Current Topics in Medicinal Chemistry. 9: 1678-87. PMID 19929835 DOI: 10.2174/156802609790102383  0.511
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