Ming-Sound Tsao - Publications

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Oncology, Molecular Biology, Cell Biology, General Biophysics

367 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ran X, Wu BX, Shi M, Song L, Nixon K, Philip V, He HH, Tsao MS, Lok BH. CRISPR screen of druggable targets in small cell lung cancer identified ATM inhibitor (AZD1390) as a radiosensitizer. International Journal of Radiation Oncology, Biology, Physics. PMID 38104868 DOI: 10.1016/j.ijrobp.2023.12.011  0.349
2023 Dacic S, Travis W, Redman M, Saqi A, Cooper WA, Borczuk A, Chung JH, Glass C, Lopez JM, Roden AC, Sholl L, Weissferdt A, Posadas J, Walker A, Zhu H, ... ... Tsao MS, et al. International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37702631 DOI: 10.1016/j.jtho.2023.07.017  0.321
2022 Ji L, Moghal N, Zou X, Fang Y, Hu S, Wang Y, Tsao MS. The NRF2 antagonist ML385 inhibits PI3K-mTOR signaling and growth of lung squamous cell carcinoma cells. Cancer Medicine. PMID 36305267 DOI: 10.1002/cam4.5311  0.308
2022 Garcia-Pardo M, Czarnecka K, Law JH, Salvarrey A, Fernandes R, Fan J, Corke L, Waddell TK, Yasufuku K, Donahoe LL, Pierre A, Le LW, Ghumman N, Liu G, Shepherd FA, ... ... Tsao MS, et al. Plasma-first: accelerating lung cancer diagnosis and molecular profiling through liquid biopsy. Therapeutic Advances in Medical Oncology. 14: 17588359221126151. PMID 36158638 DOI: 10.1177/17588359221126151  0.325
2022 Mirhadi S, Tam S, Li Q, Moghal N, Pham NA, Tong J, Golbourn BJ, Krieger JR, Taylor P, Li M, Weiss J, Martins-Filho SN, Raghavan V, Mamatjan Y, Khan AA, ... ... Tsao MS, et al. Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes. Nature Communications. 13: 1811. PMID 35383171 DOI: 10.1038/s41467-022-29444-9  0.378
2022 Perdrizet K, Stockley TL, Law JH, Smith A, Zhang T, Fernandes R, Shabir M, Sabatini P, Youssef NA, Ishu C, Li JJ, Tsao MS, Pal P, Cabanero M, Schwock J, et al. Integrating comprehensive genomic sequencing of non-small cell lung cancer into a public healthcare system. Cancer Treatment and Research Communications. 31: 100534. PMID 35278845 DOI: 10.1016/j.ctarc.2022.100534  0.324
2021 Melosky B, Cheema P, Juergens RA, Leighl NB, Liu G, Wheatley-Price P, Sacher A, Snow S, Tsao MS, McLeod D, Chu Q. The dawn of a new era, adjuvant EGFR inhibition in resected non-small cell lung cancer. Therapeutic Advances in Medical Oncology. 13: 17588359211056306. PMID 34804219 DOI: 10.1177/17588359211056306  0.304
2021 Saraon P, Snider J, Schormann W, Rai A, Radulovich N, Sánchez-Osuna M, Coulombe-Huntington J, Huard C, Mohammed M, Lima-Fernandes E, Thériault B, Halabelian L, Chan M, Joshi D, Drecun L, ... ... Tsao MS, et al. Chemical genetics screen identifies COPB2 tool compounds that alters ER stress response and induces RTK dysregulation in lung cancer cells. Journal of Molecular Biology. 167294. PMID 34662547 DOI: 10.1016/j.jmb.2021.167294  0.333
2021 Cheung CC, Smith AC, Albadine R, Bigras G, Bojarski A, Couture C, Cutz JC, Huang WY, Ionescu D, Itani D, Izevbaye I, Karsan A, Kelly MM, Knoll J, Kwan K, ... ... Tsao MS, et al. Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 160: 127-135. PMID 34509095 DOI: 10.1016/j.lungcan.2021.08.003  0.356
2021 Melosky B, Wheatley-Price P, Juergens RA, Sacher A, Leighl NB, Tsao MS, Cheema P, Snow S, Liu G, Card PB, Chu Q. The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). PMID 34353680 DOI: 10.1016/j.lungcan.2021.06.002  0.314
2021 Rosen JC, Weiss J, Pham NA, Li Q, Martins-Filho SN, Wang Y, Tsao MS, Moghal N. Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts. Translational Oncology. 14: 101179. PMID 34284202 DOI: 10.1016/j.tranon.2021.101179  0.394
2021 Fung AS, Karimi M, Michiels S, Seymour L, Brambilla E, Le-Chevalier T, Soria JC, Kratzke R, Graziano SL, Devarakonda S, Govindan R, Tsao MS, Shepherd FA. Prognostic and predictive effect of gene copy number and mutation status in early stage non-small cell lung cancer patients. Translational Lung Cancer Research. 10: 826-838. PMID 33718025 DOI: 10.21037/tlcr-20-927  0.353
2020 Huo KG, D'Arcangelo E, Tsao MS. Patient-derived cell line, xenograft and organoid models in lung cancer therapy. Translational Lung Cancer Research. 9: 2214-2232. PMID 33209645 DOI: 10.21037/Tlcr-20-154  0.446
2020 Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bossé Y, Lam S, Tsao MS, Tardon A, Chen C, Doherty J, Goodman G, Bojesen SE, Landi MT, et al. Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer. Genetic Epidemiology. PMID 32924180 DOI: 10.1002/Gepi.22358  0.414
2020 Derouet MF, Allen J, Wilson GW, Ng C, Radulovich N, Kalimuthu S, Tsao MS, Darling GE, Yeung JC. Towards personalized induction therapy for esophageal adenocarcinoma: organoids derived from endoscopic biopsy recapitulate the pre-treatment tumor. Scientific Reports. 10: 14514. PMID 32884042 DOI: 10.1093/Dote/Doaa087.86  0.348
2020 Yoon JY, Nayyar R, Quest G, Pabedinskas D, Pal P, Tsao MS, Schwock J, Ko HM. PD-L1 lineage-specific quantification in malignant pleural effusions of lung adenocarcinoma by flow cytometry. Lung Cancer (Amsterdam, Netherlands). 148: 55-61. PMID 32799091 DOI: 10.1016/J.Lungcan.2020.07.013  0.302
2020 Reis PP, Drigo SA, Carvalho RF, Lopez Lapa RM, Felix TF, Patel D, Cheng D, Pintilie M, Liu G, Tsao MS. Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways. Cancers. 12. PMID 32726984 DOI: 10.3390/Cancers12082071  0.356
2020 Bueno R, Richards WG, Harpole DH, Ballman KV, Tsao MS, Chen Z, Wang X, Chen G, Chirieac LR, Chui MH, Franklin WA, Giordano TJ, Govindan R, Joshi MB, Merrick DT, et al. Multi-institutional prospective validation of prognostic mRNA signatures in early stage squamous lung cancer (Alliance). Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32717408 DOI: 10.1016/J.Jtho.2020.07.005  0.417
2020 Lou SK, Ko HM, Kinoshita T, MacDonald S, Weiss J, Czarnecka-Kujawa K, Boerner SL, Yasufuku K, Tsao MS, Schwock J. Implementation of PD-L1 22C3 IHC pharmDxTM in Cell Block Preparations of Lung Cancer: Concordance with Surgical Resections and Technical Validation of CytoLyt® Prefixation. Acta Cytologica. 1-11. PMID 32599583 DOI: 10.1159/000508628  0.355
2020 Gagné A, Orain M, Ionescu D, Tsao MS, Joubert D, Joubert P. Comprehensive assessment of PD-L1 immunohistochemistry on paired tissue and cytology specimens from non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 146: 276-284. PMID 32593917 DOI: 10.1016/J.Lungcan.2020.06.002  0.322
2020 Fares AF, Lok BH, Zhang T, Cabanero M, Lau SCM, Stockley T, Patel D, Bradbury PA, Sacher A, Yasufuku K, Morash BA, Sabatini PJB, Nguyen LN, Leighl NB, Tsao MS, et al. ALK-rearranged lung adenocarcinoma transformation into high-grade large cell neuroendocrine carcinoma: Clinical and molecular description of two cases. Lung Cancer (Amsterdam, Netherlands). PMID 32546380 DOI: 10.1016/J.Lungcan.2020.06.005  0.383
2020 Shi R, Filho SNM, Li M, Fares A, Weiss J, Pham NA, Ludkovski O, Raghavan V, Li Q, Ravi D, Cabanero M, Moghal N, Leighl NB, Bradbury P, Sacher A, ... ... Tsao MS, et al. BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer. Lung Cancer (Amsterdam, Netherlands). 146: 78-85. PMID 32521388 DOI: 10.1016/J.Lungcan.2020.05.018  0.392
2020 Farhan M, Silva M, Li S, Yan F, Fang J, Peng T, Hu J, Tsao MS, Little P, Zheng W. The role of FOXOs and autophagy in cancer and metastasis-Implications in therapeutic development. Medicinal Research Reviews. PMID 32474970 DOI: 10.1002/Med.21695  0.374
2020 Martins-Filho SN, Weiss J, Pham NA, Li Q, Cabanero M, Fares A, Stewart EL, Shi R, Patel D, Pal P, McConnell J, Bradbury PA, Sacher AG, Leighl NB, Grindlay A, ... ... Tsao MS, et al. EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models. Lung Cancer (Amsterdam, Netherlands). 145: 144-151. PMID 32447118 DOI: 10.1016/J.Lungcan.2020.03.022  0.435
2020 Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, ... ... Tsao MS, et al. Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications. 11: 2220. PMID 32393777 DOI: 10.1038/S41467-020-15905-6  0.316
2020 Schmid S, Stewart EL, Martins-Filho SN, Cabanero M, Wang A, Bao H, Wu X, Patel D, Chen Z, Law JH, Bradbury PA, Shepherd FA, Leighl N, Tsao MS, Pugh T, et al. Early Detection of Multiple Resistance Mechanisms by ctDNA Profiling in a Patient With EGFR-mutant Lung Adenocarcinoma Treated With Osimertinib. Clinical Lung Cancer. PMID 32389504 DOI: 10.1016/J.Cllc.2020.03.009  0.383
2020 Golaraei A, Mostaço-Guidolin LB, Raja V, Navab R, Wang T, Sakashita S, Yasufuku K, Tsao MS, Wilson BC, Barzda V. Polarimetric second-harmonic generation microscopy of the hierarchical structure of collagen in stage I-III non-small cell lung carcinoma. Biomedical Optics Express. 11: 1851-1863. PMID 32341852 DOI: 10.1364/Boe.387744  0.366
2020 Hai J, Zhang H, Zhou J, Wu Z, Chen T, Papadopoulos E, Dowling CM, Pyon V, Pan Y, Liu JB, Bronson RT, Silver H, Lizotte PH, Deng J, Campbell JD, ... ... Tsao MS, et al. Generation of genetically engineered mouse lung organoid models for squamous cell lung cancers allows for the study of combinatorial immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32209571 DOI: 10.1158/1078-0432.Ccr-19-1627  0.42
2020 Juergens RA, Hao D, Ellis PM, Tu D, Mates M, Kollmannsberger C, Bradbury PA, Tehfe M, Wheatley-Price P, Robinson A, Bebb G, Laskin J, Goffin J, Hilton J, Tomiak A, ... ... Tsao MS, et al. A phase IB study of durvalumab with or without tremelimumab and platinum-doublet chemotherapy in advanced solid tumours: Canadian Cancer Trials Group Study IND226. Lung Cancer (Amsterdam, Netherlands). 143: 1-11. PMID 32169783 DOI: 10.1016/J.Lungcan.2020.02.016  0.331
2020 Saraon P, Snider J, Kalaidzidis Y, Wybenga-Groot LE, Weiss K, Rai A, Radulovich N, Drecun L, Vučković N, Vučetić A, Wong V, Thériault B, Pham NA, Park JH, Datti A, ... ... Tsao MS, et al. A drug discovery platform to identify compounds that inhibit EGFR triple mutants. Nature Chemical Biology. PMID 32094923 DOI: 10.1038/S41589-020-0484-2  0.316
2020 Rudkowski JL, Pond GR, Tremblay A, Johnston M, Goss G, Nicholas G, Martel S, Bhatia R, Liu G, Schmidt H, Tammemagi MC, Atkar-Khattra S, Tsao MS, Lam S, Goffin JR. Trial marketing in the Pan-Canadian Early Detection of Lung Cancer Study. Clinical Trials (London, England). 1740774519895966. PMID 31894702 DOI: 10.1177/1740774519895966  0.356
2020 Gauthier M, Karimi M, Michiels S, Seymour L, Brambilla E, Chevalier TL, Soria J, Kratzke RA, Graziano SL, Govindan R, Tsao M, Shepherd FA. Role of the total mutation burden (TMB) and tumor-infiltrating lymphocytes (TILs) on the development of second primary cancer after complete resection of non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E21092  0.465
2020 Fung AS, Karimi M, Michiels S, Seymour L, Brambilla E, Chevalier TL, Soria J, Kratzke RA, Graziano SL, Devarakonda S, Govindan R, Tsao M, Shepherd FA. Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer (NSCLC) patients. Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E21080  0.414
2020 Lau SC, Wong SW, Wang BX, Patel D, Fares AF, Tsao M, Bradbury PA, Liu G, Leighl NB, Shepherd FA, Ohashi PS, Sacher AG. Rapid expansion of M-MDSCs and association with high levels of plasma TSLP and primary resistance to PD-1 inhibitors in metastatic NSCLC. Journal of Clinical Oncology. 38: 3084-3084. DOI: 10.1200/Jco.2020.38.15_Suppl.3084  0.342
2020 Lau SC, Soleimani S, Wong SW, Pedersen S, Wang BX, Elkrief A, Patel D, Fares AF, Jao K, Daaboul N, Hakozaki T, Bradbury PA, Liu G, Leighl NB, Tsao M, et al. TCR clonality and Treg frequency as predictors of outcome in stage III NSCLC treated with durvalumab. Journal of Clinical Oncology. 38: 3050-3050. DOI: 10.1200/Jco.2020.38.15_Suppl.3050  0.36
2019 Edwards JG, Chansky K, van Schil P, Nicholson AG, Boubia S, Brambilla E, Donnington J, Galateau-Sallé F, Hoffman H, Infante M, Marino M, Marom E, Nakajima J, Ostrowski M, Travis WD, ... Tsao MS, et al. The IASLC Lung Cancer Staging Project: Analysis of Resection Margin Status and Proposals for Residual Tumor (R) Descriptors for Non-Small Cell Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 31731014 DOI: 10.1016/J.Jtho.2019.10.019  0.436
2019 Shi R, Radulovich N, Ng C, Liu N, Notsuda H, Cabanero M, N Martins-Filho S, Raghavan V, Li Q, Mer AS, Rosen JC, Li M, Wang YH, Tamblyn L, Pham NA, ... ... Tsao MS, et al. Organoid cultures as preclinical models of non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31694835 DOI: 10.1158/1078-0432.Ccr-19-1376  0.455
2019 Cheung CC, Barnes P, Bigras G, Boerner S, Butany J, Calabrese F, Couture C, Deschenes J, El-Zimaity H, Fischer G, Fiset PO, Garratt J, Geldenhuys L, Gilks CB, Ilie M, ... ... Tsao MS, et al. Fit-For-Purpose PD-L1 Biomarker Testing For Patient Selection in Immuno-Oncology: Guidelines For Clinical Laboratories From the Canadian Association of Pathologists-Association Canadienne Des Pathologistes (CAP-ACP). Applied Immunohistochemistry & Molecular Morphology : Aimm. PMID 31584451 DOI: 10.1097/Pai.0000000000000800  0.362
2019 Marchevsky AM, Khoor A, Walts AE, Nicholson AG, Zhang YZ, Roggli V, Carney J, Roden AC, Tazelaar HD, Larsen BT, LeStang N, Chirieac LR, Klebe S, Tsao MS, De Perrot M, et al. Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31485011 DOI: 10.1038/S41379-019-0352-3  0.312
2019 Joseph J, Radulovich N, Wang T, Raghavan V, Zhu CQ, Tsao MS. Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma. Oncogene. PMID 31477830 DOI: 10.1038/S41388-019-0985-1  0.441
2019 Ji L, Zhang R, Chen J, Xue Q, Moghal N, Tsao MS. PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC. Scientific Reports. 9: 12437. PMID 31455821 DOI: 10.1038/S41598-019-48763-4  0.401
2019 Fiset PO, Labbé C, Young K, Craddock KJ, Smith AC, Tanguay J, Pintilie M, Wang R, Torlakovic E, Cheung C, da Cunha Santos G, Ko HM, Boerner SL, Hwang DM, Leighl NB, ... Tsao MS, et al. Anaplastic lymphoma kinase 5A4 immunohistochemistry as a diagnostic assay in lung cancer: A Canadian reference testing center's results in population-based reflex testing. Cancer. PMID 31390053 DOI: 10.1002/Cncr.32422  0.337
2019 Ishizawa K, Yamanaka M, Saiki Y, Miyauchi E, Fukushige S, Akaishi T, Asao A, Mimori T, Saito R, Tojo Y, Yamashita R, Abe M, Sakurada A, Pham NA, Li M, ... ... Tsao MS, et al. CD45+CD326+ Cells are predictive of poor prognosis in Non-Small Cell Lung Cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31383733 DOI: 10.1158/1078-0432.Ccr-19-0545  0.401
2019 Wang D, Pham NA, Freeman TM, Raghavan V, Navab R, Chang J, Zhu CQ, Ly D, Tong J, Wouters BG, Pintilie M, Moran MF, Liu G, Shepherd FA, Tsao MS. Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer. Cancers. 11. PMID 31330989 DOI: 10.3390/Cancers11071009  0.468
2019 Lee SL, Cabanero M, Hyrcza M, Butler M, Liu FF, Hansen A, Huang SH, Tsao MS, Song Y, Lu L, Xu W, Chepeha DB, Goldstein DP, Weinreb I, Bratman SV. Computer-assisted image analysis of the tumor microenvironment on an oral tongue squamous cell carcinoma tissue microarray. Clinical and Translational Radiation Oncology. 17: 32-39. PMID 31193592 DOI: 10.1016/J.Ctro.2019.05.001  0.342
2019 Mer AS, Ba-Alawi W, Smirnov P, Wang YX, Brew B, Ortmann J, Tsao MS, Cescon DW, Goldenberg A, Haibe-Kains B. Integrative pharmacogenomics analysis of patient-derived xenografts. Cancer Research. PMID 31142512 DOI: 10.1158/0008-5472.Can-19-0349  0.327
2019 Melosky B, Juergens R, Hirsh V, McLeod D, Leighl N, Tsao MS, Card PB, Chu Q. Amplifying Outcomes: Checkpoint Inhibitor Combinations in First-Line Non-Small Cell Lung Cancer. The Oncologist. PMID 31138727 DOI: 10.1634/Theoncologist.2019-0027  0.454
2019 Zeltz C, Pasko E, Cox TR, Navab R, Tsao MS. LOXL1 Is Regulated by Integrin α11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity. Cancers. 11. PMID 31121900 DOI: 10.3390/Cancers11050705  0.434
2019 Hao J, Zeltz C, Pintilie M, Li Q, Sakashita S, Wang T, Cabanero M, Martins-Filho SN, Wang DY, Pasko E, Venkat K, Joseph J, Raghavan V, Zhu CQ, Wang YH, ... ... Tsao MS, et al. Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion. Neoplasia (New York, N.Y.). 21: 482-493. PMID 30978569 DOI: 10.1016/J.Neo.2019.03.009  0.504
2019 Wang H, Sun L, Sang Y, Yang X, Tian G, Wang Z, Fang J, Sun W, Zhou L, Jia L, Tsao MS, Shi H, Lin D. A study of ALK-positive pulmonary squamous-cell carcinoma: From diagnostic methodologies to clinical efficacy. Lung Cancer (Amsterdam, Netherlands). 130: 135-142. PMID 30885334 DOI: 10.1016/J.Lungcan.2019.02.015  0.395
2019 Fang L, Ly D, Wang SS, Lee JB, Kang H, Xu H, Yao J, Tsao MS, Liu W, Zhang L. Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade. Journal of Experimental & Clinical Cancer Research : Cr. 38: 123. PMID 30857561 DOI: 10.1186/S13046-019-1126-Y  0.425
2019 Yao J, Ly D, Dervovic D, Fang L, Lee JB, Kang H, Wang YH, Pham NA, Pan H, Tsao MS, Zhang L. Human double negative T cells target lung cancer via ligand-dependent mechanisms that can be enhanced by IL-15. Journal For Immunotherapy of Cancer. 7: 17. PMID 30670085 DOI: 10.1186/S40425-019-0507-2  0.433
2019 Gendoo DMA, Denroche RE, Zhang A, Radulovich N, Jang GH, Lemire M, Fischer S, Chadwick D, Lungu IM, Ibrahimov E, Cao PJ, Stein LD, Wilson JM, Bartlett JMS, Tsao MS, et al. Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer. Plos Computational Biology. 15: e1006596. PMID 30629588 DOI: 10.1371/Journal.Pcbi.1006596  0.33
2019 Mamatjan Y, Cabanero M, Weiss J, Zuccato J, Sorotsky H, Tsao MS, Aldape KD, Zadeh G, Shepherd FA. Methylation profiling of EGFR mutant primary and metastatic lung cancer with brain metastasis. Journal of Clinical Oncology. 37: e20574-e20574. DOI: 10.1200/Jco.2019.37.15_Suppl.E20574  0.312
2019 Yu H, Merrick DT, Tsao M, Richards WG, Chirieac LR, Watson MA, Rivard CJ, Harpole DH, Bueno R, Bokhoven Av, Tan A, Hirsch FR, Franklin WA. Abstract 4550: Correlations between tumor mutation burden, inflammatory profile and histological characteristics of tumor microenvironment in early-stage squamous cell lung carcinoma Cancer Research. 79: 4550-4550. DOI: 10.1158/1538-7445.Sabcs18-4550  0.405
2019 Mer AS, Ba-alawi W, Smirnov P, Wang YX, Brew B, Tsao M, Cescon D, Goldenberg A, Haibe-Kains B. Abstract 3378: Systematic pharmacogenomic analysis of large patient derived xenografts data Cancer Research. 79: 3378-3378. DOI: 10.1158/1538-7445.Am2019-3378  0.375
2018 Tomasini P, Mascaux C, Jao K, Labbe C, Kamel-Reid S, Stockley T, Hwang DM, Leighl NB, Liu G, Bradbury PA, Pintilie M, Tsao MS, Shepherd FA. Effect of Coexisting KRAS and TP53 Mutations in Patients Treated With Chemotherapy for Non-small-cell Lung Cancer. Clinical Lung Cancer. PMID 30770327 DOI: 10.1016/J.Cllc.2018.12.009  0.449
2018 Dai J, Li Z, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, van der Heijden EHFM, Duell E, Rennert G, James MD, Yuan JM, Field JK, ... ... Tsao MS, et al. Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci. Carcinogenesis. PMID 30590402 DOI: 10.1093/Carcin/Bgy187  0.329
2018 Yatabe Y, Dacic S, Borczuk AC, Warth A, Russell PA, Lantuejoul S, Beasley MB, Thunnissen E, Pelosi G, Rekhtman N, Bubendorf L, Mino-Kenudson M, Yoshida A, Geisinger KR, Noguchi M, ... ... Tsao MS, et al. Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 30572031 DOI: 10.1016/j.jtho.2018.12.005  0.356
2018 Seymour L, Le Teuff G, Brambilla E, Shepherd FA, Soria JC, Kratzke R, Graziano S, Douillard JY, Rosell R, Reiman A, Lacas B, Lueza B, Aviel-Ronen S, McLeer A, Le Chevalier T, ... ... Tsao MS, et al. LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry-based Biomarkers in Resected Non-small-cell Lung Cancer. Clinical Lung Cancer. PMID 30414783 DOI: 10.1016/J.Cllc.2018.10.001  0.46
2018 Tammemagi M, Ritchie AJ, Atkar-Khattra S, Dougherty B, Sanghera C, Mayo JR, Yuan R, Manos D, McWilliams AM, Schmidt H, Gingras M, Pasian S, Stewart L, Tsai S, Seely JM, ... ... Tsao MS, et al. Predicting Malignancy Risk of Screen Detected Lung Nodules - Mean Diameter or Volume. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 30368011 DOI: 10.1016/J.Jtho.2018.10.006  0.347
2018 Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, ... ... Tsao MS, et al. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nature Communications. 9: 3927. PMID 30254314 DOI: 10.1038/S41467-018-05890-2  0.372
2018 Lee DH, Tsao MS, Kambartel KO, Isobe H, Huang MS, Barrios CH, Khattak A, de Marinis F, Kothari S, Arunachalam A, Cao X, Burke T, Valladares A, de Castro J. Molecular testing and treatment patterns for patients with advanced non-small cell lung cancer: PIvOTAL observational study. Plos One. 13: e0202865. PMID 30148862 DOI: 10.1371/journal.pone.0202865  0.337
2018 Devarakonda S, Rotolo F, Tsao MS, Lanc I, Brambilla E, Masood A, Olaussen KA, Fulton R, Sakashita S, McLeer-Florin A, Ding K, Le Teuff G, Shepherd FA, Pignon JP, Graziano SL, et al. Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018781963. PMID 30106638 DOI: 10.1200/JCO.2018.78.1963  0.357
2018 Shi R, Li M, Raghavan V, Tam S, Cabanero M, Pham NA, Shepherd FA, Moghal N, Tsao MS. Targeting the CDK4/6-Rb pathway enhances response to PI3K inhibition in PIK3CA mutant lung squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30093452 DOI: 10.1158/1078-0432.Ccr-18-0717  0.432
2018 Jao K, Tomasini P, Kamel-Reid S, Korpanty GJ, Mascaux C, Sakashita S, Labbé C, Leighl NB, Liu G, Feld R, Bradbury PA, Hwang DM, Pintilie M, Tsao MS, Shepherd FA. The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 123: 22-29. PMID 30089591 DOI: 10.1016/J.Lungcan.2018.06.023  0.463
2018 Rotolo F, Zhu CQ, Brambilla E, Graziano SL, Olaussen K, Le-Chevalier T, Pignon JP, Kratzke R, Soria JC, Shepherd FA, Seymour L, Michiels S, Tsao MS. Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer. Translational Lung Cancer Research. 7: 416-427. PMID 30050779 DOI: 10.21037/Tlcr.2018.05.01  0.458
2018 Korpanty GJ, Kamel-Reid S, Pintilie M, Hwang DM, Zer A, Liu G, Leighl NB, Feld R, Siu LL, Bedard PL, Tsao MS, Shepherd FA. Lung cancer in never smokers from the Princess Margaret Cancer Centre. Oncotarget. 9: 22559-22570. PMID 29854298 DOI: 10.18632/Oncotarget.25176  0.419
2018 Tsao MS, Yoon JY. The eighth TNM classification for lung cancer-What is next? Lung Cancer (Amsterdam, Netherlands). PMID 29724454 DOI: 10.1016/J.Lungcan.2018.04.018  0.417
2018 Dhont L, Pintilie M, Kaufman E, Navab R, Tam S, Burny A, Shepherd F, Belayew A, Tsao MS, Mascaux C. Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC). Bmc Cancer. 18: 429. PMID 29661164 DOI: 10.1186/S12885-018-4215-Y  0.494
2018 Gebregiworgis T, Marshall CB, Nishikawa T, Radulovich N, Sandi MJ, Fang Z, Rottapel R, Tsao MS, Ikura M. Multiplexed real-time NMR GTPase assay for simultaneous monitoring of multiple GEF activities from human cancer cells and organoids. Journal of the American Chemical Society. PMID 29543440 DOI: 10.1021/Jacs.7B13703  0.39
2018 Mascaux C, Tsao MS, Hirsch FR. Genomic Testing in Lung Cancer: Past, Present, and Future. Journal of the National Comprehensive Cancer Network : Jnccn. 16: 323-334. PMID 29523671 DOI: 10.6004/Jnccn.2017.7019  0.442
2018 Tokar T, Pastrello C, Ramnarine VR, Zhu CQ, Craddock KJ, Pikor LA, Vucic EA, Vary S, Shepherd FA, Tsao MS, Lam WL, Jurisica I. Differentially expressed microRNAs in lung adenocarcinoma invert effects of copy number aberrations of prognostic genes. Oncotarget. 9: 9137-9155. PMID 29507679 DOI: 10.18632/Oncotarget.24070  0.417
2018 Yoshimoto M, Ludkovski O, Good J, Pereira C, Gooding RJ, McGowan-Jordan J, Boag A, Evans A, Tsao MS, Nuin P, Squire JA. Use of multicolor fluorescence in situ hybridization to detect deletions in clinical tissue sections. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29339834 DOI: 10.1038/S41374-017-0007-2  0.327
2018 Sorotsky H, Moskovitz M, Weiss J, Pintilie M, Leighl NB, Bradbury PA, Liu G, Kia A, Cabanero M, Pugh TJ, Torti D, Tsao MS, Torchia J, Shepherd FA. The effect of prior smoking history on the molecular profile of EGFR mutant (EGFRm) non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 36: 8533-8533. DOI: 10.1200/jco.2018.36.15_suppl.8533  0.323
2018 Perdrizet K, Stockley T, Tsao MS, Morganstein J, Kamel-Reid S, Ranich L, Shepherd FA, Liu G, Bradbury PA, Hwang D, Pal P, Schwock J, Boerner SL, Law JH, Leighl NB. Upfront next generation sequencing in NSCLC: A publicly funded perspective. Journal of Clinical Oncology. 36: 12062-12062. DOI: 10.1200/Jco.2018.36.15_Suppl.12062  0.315
2018 Gebregiworgis T, Marshall CB, Kano Y, Radulovich N, Tsao M, Ohh M, Ikura M. Abstract 4360: Altering the regulation of KRAS GTPase cycle via Src and SHP2 creates a potential therapeutic vulnerability for pancreatic cancer Cancer Research. 78: 4360-4360. DOI: 10.1158/1538-7445.Am2018-4360  0.366
2018 Kano Y, Gebregiworgis T, Marshall CB, Radulovich N, Poon BP, Zhang Z, Tsao M, Ikura M, Ohh M. 833 - Tyrosyl Phosphorylation of Kras Disrupts the Gtpase Cycle and Inhibits Pancreatic Cancer Cell Growth Gastroenterology. 154: S-173. DOI: 10.1016/S0016-5085(18)30991-0  0.365
2018 Gagné A, Orain M, Ionescu D, Tsao M, Joubert D, Joubert P. P2.09-02 Comprehensive Assessment of PD-L1 Immunohistochemistry on Paired Tissue and Cytology Specimens in Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 13. DOI: 10.1016/J.Jtho.2018.08.1299  0.39
2017 Brana I, Pham NA, Kim L, Sakashita S, Li M, Ng C, Wang Y, Loparco P, Sierra R, Wang L, Clarke BA, Neel BG, Siu LL, Tsao MS. Novel combinations of PI3K-mTOR inhibitors with dacomitinib or chemotherapy in PTEN-deficient patient-derived tumor xenografts. Oncotarget. 8: 84659-84670. PMID 29156674 DOI: 10.18632/Oncotarget.19109  0.403
2017 Chiu JW, Krzyzanowska MK, Serra S, Knox JJ, Dhani NC, Mackay H, Hedley D, Moore M, Liu G, Burkes RL, Brezden-Masley C, Roehrl MH, Craddock KJ, Tsao MS, Zhang T, et al. Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience. Clinical Colorectal Cancer. PMID 29128266 DOI: 10.1016/J.Clcc.2017.10.010  0.371
2017 Tammemagi MC, Schmidt H, Martel S, McWilliams A, Goffin JR, Johnston MR, Nicholas G, Tremblay A, Bhatia R, Liu G, Soghrati K, Yasufuku K, Hwang DM, Laberge F, Gingras M, ... ... Tsao MS, et al. Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study. The Lancet. Oncology. PMID 29055736 DOI: 10.1016/S1470-2045(17)30597-1  0.414
2017 Leighl NB, Tsao MS, Liu G, Tu D, Ho C, Shepherd FA, Murray N, Goffin JR, Nicholas G, Sakashita S, Chen Z, Kim L, Powers J, Seymour L, Goss G, et al. A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196. Oncotarget. 8: 69651-69662. PMID 29050231 DOI: 10.18632/Oncotarget.18753  0.428
2017 Kim L, Saieg M, Di Maio M, Gallo C, Butts C, Ciardiello F, Feld R, Cheng D, Gebbia V, Burgio MA, Alam Y, Signoriello S, Rossi A, Leighl N, Maione P, ... ... Tsao MS, et al. Biomarker analysis of the phase 3 TORCH trial for first line erlotinib versus chemotherapy in advanced non-small cell lung cancer patients. Oncotarget. 8: 57528-57536. PMID 28915692 DOI: 10.18632/oncotarget.15725  0.331
2017 Labbé C, Cabanero M, Korpanty GJ, Tomasini P, Doherty MK, Mascaux C, Jao K, Pitcher B, Wang R, Pintilie M, Leighl NB, Feld R, Liu G, Bradbury PA, Kamel-Reid S, ... Tsao MS, et al. Prognostic and predictive effects of TP53 co-mutation in patients with EGFR-mutated non-small cell lung cancer (NSCLC). Lung Cancer (Amsterdam, Netherlands). 111: 23-29. PMID 28838393 DOI: 10.1200/Jco.2016.34.15_Suppl.11585  0.422
2017 Hai J, Liu S, Bufe L, Do K, Chen T, Wang X, Ng C, Li S, Tsao MS, Shapiro GI, Wong KK. Synergy of WEE1 and mTOR inhibition in mutant KRAS-driven lung cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28821559 DOI: 10.1158/1078-0432.Ccr-17-1098  0.46
2017 Kim BR, Coyaud E, Laurent E, St-Germain J, Van de Laar E, Tsao MS, Raught B, Moghal N. Identification of the SOX2 interactome by BioID reveals EP300 as a mediator of SOX2-dependent squamous differentiation and lung squamous cell carcinoma growth. Molecular & Cellular Proteomics : McP. PMID 28794006 DOI: 10.1074/Mcp.M116.064451  0.44
2017 Ly D, Zhu CQ, Cabanero M, Tsao MS, Zhang L. Role for high-affinity IgE receptor in prognosis of lung adenocarcinoma patients. Cancer Immunology Research. PMID 28775209 DOI: 10.1158/2326-6066.Cir-16-0392  0.473
2017 Leighl NB, Tsao MS, Liu G, Tu D, Ho C, Shepherd FA, Murray N, Goffin JR, Nicholas G, Sakashita S, Chen Z, Kim L, Powers J, Seymour L, Goss G, et al. A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196. Oncotarget. PMID 28706139 DOI: 10.18632/oncotarget.18753  0.316
2017 Lewis AM, Ough M, Du J, Tsao MS, Oberley LW, Cullen JJ. Targeting NAD(P)H:Quinone Oxidoreductase (NQO1) in Pancreatic Cancer. Molecular Carcinogenesis. 56: 1825-1834. PMID 28639725 DOI: 10.1002/Mc.20199  0.394
2017 McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, ... ... Tsao MS, et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nature Genetics. PMID 28604730 DOI: 10.1038/Ng.3892  0.435
2017 Shepherd FA, Lacas B, Le Teuff G, Hainaut P, Jänne PA, Pignon JP, Le Chevalier T, Seymour L, Douillard JY, Graziano S, Brambilla E, Pirker R, Filipits M, Kratzke R, Soria JC, ... Tsao MS, et al. Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016712893. PMID 28453411 DOI: 10.1200/Jco.2016.71.2893  0.423
2017 Kim L, Saieg M, Di Maio M, Gallo C, Butts C, Ciardiello F, Feld R, Cheng D, Gebbia V, Burgio MA, Alam Y, Signoriello S, Rossi A, Leighl N, Maione P, ... ... Tsao MS, et al. Biomarker analysis of the phase 3 TORCH trial for first line erlotinib versus chemotherapy in advanced non-small cell lung cancer patients. Oncotarget. PMID 28427160 DOI: 10.18632/oncotarget.15725  0.331
2017 Notsuda H, Bradbury PA, Tsao MS. HER2 Transmembrane Domain Mutations: Rare New Target for Non-Small Cell Lung Cancer Therapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 12: 422-424. PMID 28215721 DOI: 10.1016/J.Jtho.2017.01.007  0.422
2017 Juergens RA, Bratman SV, Tsao MS, Laurie SA, Sara Kuruvilla M, Razak AR, Hansen AR. Biology and patterns of response to EGFR-inhibition in squamous cell cancers of the lung and head & neck. Cancer Treatment Reviews. 54: 43-57. PMID 28192747 DOI: 10.1016/J.Ctrv.2017.01.003  0.382
2017 Hai J, Zhu CQ, Wang T, Organ SL, Shepherd FA, Tsao MS. TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung Cancer. Scientific Reports. 7: 39692. PMID 28059079 DOI: 10.1038/Srep39692  0.503
2017 Barnes TA, Laskin JJ, Cheema PK, Liu G, Iqbal M, Rothenstein J, Burkes RL, Owen SP, Laurence D, Carvalhana I, Markin L, Wong L, Perera-Low N, Sawczak M, Tsao M, et al. Patients’ willingness to pay for blood-based EGFR T790M testing: Results from a Canadian validation study of circulating DNA T790M testing. Journal of Clinical Oncology. 35: e18329-e18329. DOI: 10.1200/Jco.2017.35.15_Suppl.E18329  0.365
2017 Ly D, Zhu C, Cabanero M, Tsao M, Zhang L. Abstract A64: Mast cell expressed FcϵR beta subunit (MS4A2) is prognostic in lung adenocarcinoma Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A64  0.475
2017 Kothari S, Arunachalam A, Tsao M, Lee D, Kambartel K, Isobe H, Huang M, Escosteguy Barrios C, Khattak A, de Marinis F, Cao X, Burke T, Lopez M, De Castro J. Utilization and Treatment Patterns Among Patients with Advanced Non-Small Cell Lung Cancer Receiving Predictive Molecular Biomarker (BMX) Tests Value in Health. 20: A400. DOI: 10.1016/J.Jval.2017.08.012  0.431
2016 Zer A, Moskovitz M, Hwang DM, Hershko-Klement A, Fridel L, Korpanty GJ, Dudnik E, Peled N, Shochat T, Leighl NB, Liu G, Feld R, Burkes R, Wollner M, Tsao MS, et al. ALK-Rearranged Non-Small-Cell Lung Cancer Is Associated With a High Rate of Venous Thromboembolism. Clinical Lung Cancer. PMID 27913214 DOI: 10.1016/J.Cllc.2016.10.007  0.461
2016 Kim BR, Van de Laar E, Cabanero M, Tarumi S, Hasenoeder S, Wang D, Virtanen C, Suzuki T, Bandarchi B, Sakashita S, Pham NA, Lee S, Keshavjee S, Waddell TK, Tsao MS, et al. SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis. Plos Biology. 14: e1002581. PMID 27880766 DOI: 10.1371/Journal.Pbio.1002581  0.378
2016 Liu G, Cuffe S, Liang S, Azad AK, Cheng L, Brhane Y, Qiu X, Cescon DW, Bruce JP, Chen Z, Cheng D, Patel D, Tse BC, Laurie SA, Goss GD, ... ... Tsao MS, et al. BRM Promoter Polymorphisms, Risk and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and NCIC CTG BR.24 trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27827316 DOI: 10.1158/1078-0432.Ccr-16-1640  0.377
2016 Stockley TL, Oza AM, Berman HK, Leighl NB, Knox JJ, Shepherd FA, Chen EX, Krzyzanowska MK, Dhani N, Joshua AM, Tsao MS, Serra S, Clarke B, Roehrl MH, Zhang T, et al. Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial. Genome Medicine. 8: 109. PMID 27782854 DOI: 10.1186/S13073-016-0364-2  0.341
2016 Wang D, Pham NA, Tong J, Sakashita S, Allo G, Kim L, Yanagawa N, Raghavan V, Wei Y, To C, Trinh QM, Starmans MH, Chan-Seng-Yue MA, Chadwick D, Li L, ... ... Tsao MS, et al. Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors. International Journal of Cancer. PMID 27750381 DOI: 10.1002/Ijc.30472  0.417
2016 Wang T, Notta F, Navab R, Joseph J, Ibrahimov E, Xu J, Zhu CQ, Borgida A, Gallinger S, Tsao MS. Senescent Carcinoma-associated Fibroblasts Upregulate IL8 to Enhance Pro-metastatic Phenotypes. Molecular Cancer Research : McR. PMID 27678171 DOI: 10.1158/1541-7786.Mcr-16-0192  0.39
2016 Shi R, Varella-Garcia M, Li M, Ludkovski O, Danesh A, Ng C, Pham NA, Pugh T, Shepherd FA, Tsao MS. An anaplastic lymphoma kinase (ALK) immunohistochemistry negative but fluorescence in situ hybridization (FISH) positive lung adenocarcinoma is resistant to Crizotinib. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27613526 DOI: 10.1016/J.Jtho.2016.08.139  0.361
2016 Wong KM, Ding K, Li S, Bradbury P, Tsao MS, Der SD, Shepherd FA, Chung C, Ng R, Seymour L, Leighl NB. A Cost-Effectiveness Analysis of Using the JBR.10-Based 15-Gene Expression Signature to Guide Adjuvant Chemotherapy in Early Stage Non-Small-Cell Lung Cancer. Clinical Lung Cancer. PMID 27502323 DOI: 10.1016/J.Cllc.2016.06.009  0.425
2016 Lohse I, Rasowski J, Cao P, Pintilie M, Do T, Tsao MS, Hill RP, Hedley DW. Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302. Oncotarget. PMID 27248663 DOI: 10.18632/Oncotarget.9654  0.331
2016 Zer A, Hershko-Klement A, Hwang D, Korpanty G, Leighl N, Liu G, Feld R, Burkes R, Tsao M, Shepherd F. 176P: ALK-rearranged non-small cell lung cancer is associated with a high rate of venous thromboembolism. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 11: S134. PMID 27198314 DOI: 10.1016/S1556-0864(16)30286-6  0.438
2016 Tremblay A, Taghizadeh N, McWilliams AM, MacEachern P, Stather DR, Soghrati K, Puksa S, Goffin JR, Yasufuku K, Amjadi K, Nicholas G, Martel S, Laberge F, Johnston M, Shepherd FA, ... ... Tsao MS, et al. Low Prevalence of High Grade Lesions Detected with Autofluorescence Bronchoscopy in the Setting of Lung Cancer Screening in the Pan-Canadian Lung Cancer Screening Study. Chest. PMID 27142184 DOI: 10.1016/J.Chest.2016.04.019  0.404
2016 Rayson D, Lupichuk S, Potvin K, Dent S, Shenkier T, Dhesy-Thind S, Ellard SL, Prady C, Salim M, Farmer P, Allo G, Tsao MS, Allan A, Ludkovski O, Bonomi M, et al. Canadian Cancer Trials Group IND197: a phase II study of foretinib in patients with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2-negative recurrent or metastatic breast cancer. Breast Cancer Research and Treatment. PMID 27116183 DOI: 10.1007/S10549-016-3812-1  0.401
2016 Sacher AG, Le LW, Lara-Guerra H, Waddell TK, Sakashita S, Chen Z, Kim L, Zhang T, Kamel-Reid S, Salvarrey A, Darling G, Yasufuku K, Keshavjee S, De Perrot M, Shepherd FA, ... ... Tsao M, et al. A window of opportunity study of potential tumor and soluble biomarkers of response to preoperative erlotinib in early stage non-small cell lung cancer. Oncotarget. PMID 27028852 DOI: 10.18632/Oncotarget.8350  0.322
2016 Tsao AS, Scagliotti GV, Bunn PA, Carbone DP, Warren GW, Bai C, de Koning HJ, Yousaf-Khan AU, McWilliams A, Tsao MS, Adusumilli PS, Rami-Porta R, Asamura H, Van Schil PE, Darling GE, et al. Scientific Advances in Lung Cancer 2015. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27013409 DOI: 10.1016/J.Jtho.2016.03.012  0.348
2016 Martin P, Stewart E, Pham NA, Mascaux C, Panchal D, Li M, Kim L, Sakashita S, Wang D, Sykes J, Friess T, Shepherd FA, Liu G, Tsao MS. Cetuximab Inhibits T790M-Mediated Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in a Lung Adenocarcinoma Patient-Derived Xenograft Mouse Model. Clinical Lung Cancer. PMID 26926157 DOI: 10.1016/J.Cllc.2016.01.002  0.404
2016 Ma X, Le Teuff G, Lacas B, Tsao MS, Graziano S, Pignon JP, Douillard JY, Le Chevalier T, Seymour L, Filipits M, Pirker R, Janne P, Shepherd FA, Brambilla E, Soria JC, et al. Prognostic and predictive effect of TP53 mutations in non-small cell lung cancer patients from adjuvant cisplatin-based therapy randomized trials: a LACE-bio pooled analysis. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26899019 DOI: 10.1016/j.jtho.2016.02.002  0.361
2016 Brambilla E, Le Teuff G, Marguet S, Lantuejoul S, Dunant A, Graziano S, Pirker R, Douillard JY, Le Chevalier T, Filipits M, Rosell R, Kratzke R, Popper H, Soria JC, Shepherd FA, ... ... Tsao MS, et al. Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 34: 1223-30. PMID 26834066 DOI: 10.1200/JCO.2015.63.0970  0.367
2016 Cuffe S, Azad AK, Qiu X, Qiu X, Brhane Y, Kuang Q, Marsh S, Savas S, Chen Z, Cheng D, Leighl NB, Goss G, Laurie SA, Seymour L, Bradbury PA, ... ... Tsao MS, et al. ABCC2 polymorphisms and survival in the Princess Margaret cohort study and the NCIC clinical trials group BR.24 trial of platinum-treated advanced stage non-small cell lung cancer patients. Cancer Epidemiology. 41: 50-56. PMID 26816351 DOI: 10.1016/J.Canep.2015.12.012  0.343
2016 Kato T, Wada H, Patel P, Hu HP, Lee D, Ujiie H, Hirohashi K, Nakajima T, Sato M, Kaji M, Kaga K, Matsui Y, Tsao MS, Yasufuku K. Overexpression of KIF23 predicts clinical outcome in primary lung cancer patients. Lung Cancer (Amsterdam, Netherlands). 92: 53-61. PMID 26775597 DOI: 10.1016/J.Lungcan.2015.11.018  0.469
2016 Cabanero M, Tsao M. Taking action on actionable mutations: a French initiative on universality in precision cancer care Translational Cancer Research. 5. DOI: 10.21037/7739  0.419
2016 Bedard PL, Oza A, Clarke B, Tsao M, Leighl NB, Chen EX, Razak A, Berman HK, Serra S, Roehrl M, Califaretti N, Trinkaus M, Zhang T, Sukhai MA, Milea A, et al. Abstract PR03: Molecular profiling of advanced solid tumors at Princess Margaret Cancer Centre and patient outcomes with genotype-matched clinical trials Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pmsclingen15-Pr03  0.378
2016 Pham N, Wang D, Tong J, Zhu C, Li L, Zhang W, Shi R, Sakashita S, Pintilie M, Moran MF, Liu G, Tsao M. Abstract B32: Fidelity of genomic and proteomic features of patient-derived xenografts of lung cancers Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-B32  0.503
2015 Cannell IG, Merrick KA, Morandell S, Zhu CQ, Braun CJ, Grant RA, Cameron ER, Tsao MS, Hemann MT, Yaffe MB. A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy. Cancer Cell. 28: 831. PMID 28843280 DOI: 10.1016/J.Ccell.2015.11.003  0.333
2015 Zer A, Ding K, Lee SM, Goss GD, Seymour L, Ellis PM, Hackshaw A, Bradbury PA, Han L, O'Callaghan CJ, Tsao MS, Shepherd FA. Pooled Analysis of the Prognostic and Predictive Value of KRAS Mutation Status and Mutation Subtype in Patients with Non-Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26749487 DOI: 10.1016/J.Jtho.2015.11.010  0.392
2015 Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JH, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, ... ... Tsao MS, et al. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1243-60. PMID 26291008 DOI: 10.1097/JTO.0000000000000630  0.328
2015 Hai J, Sakashita S, Allo G, Ludkovski O, Ng C, Shepherd FA, Tsao MS. Inhibiting MDM2-p53 Interaction Suppresses Tumor Growth in Patient-Derived Non-Small Cell Lung Cancer Xenograft Models. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1172-80. PMID 26200271 DOI: 10.1097/Jto.0000000000000584  0.435
2015 Stewart EL, Mascaux C, Pham NA, Sakashita S, Sykes J, Kim L, Yanagawa N, Allo G, Ishizawa K, Wang D, Zhu CQ, Li M, Ng C, Liu N, Pintilie M, ... ... Tsao MS, et al. Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26124487 DOI: 10.1200/Jco.2014.60.1492  0.394
2015 Huang S, Reitze NJ, Ewing AL, McCreary S, Uihlein AH, Brower SL, Wang D, Wang T, Gabrin MJ, Keating KE, Mulligan J, Wilson C, Davison T, McKenzie S, Tsao MS, et al. Analytical Performance of a 15-Gene Prognostic Assay for Early-Stage Non-Small-Cell Lung Carcinoma Using RNA-Stabilized Tissue. The Journal of Molecular Diagnostics : Jmd. 17: 438-45. PMID 25960256 DOI: 10.1016/J.Jmoldx.2015.03.005  0.34
2015 Tsao MS, Marguet S, Le Teuff G, Lantuejoul S, Shepherd FA, Seymour L, Kratzke R, Graziano SL, Popper HH, Rosell R, Douillard JY, Le-Chevalier T, Pignon JP, Soria JC, Brambilla EM. Subtype Classification of Lung Adenocarcinoma Predicts Benefit From Adjuvant Chemotherapy in Patients Undergoing Complete Resection. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 3439-46. PMID 25918286 DOI: 10.1200/JCO.2014.58.8335  0.301
2015 Stewart EL, Tan SZ, Liu G, Tsao MS. Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations-a review. Translational Lung Cancer Research. 4: 67-81. PMID 25806347 DOI: 10.3978/J.Issn.2218-6751.2014.11.06  0.43
2015 Cescon DW, She D, Sakashita S, Zhu CQ, Pintilie M, Shepherd FA, Tsao MS. NRF2 Pathway Activation and Adjuvant Chemotherapy Benefit in Lung Squamous Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2499-505. PMID 25739673 DOI: 10.1158/1078-0432.Ccr-14-2206  0.426
2015 Leung JM, Mayo J, Tan W, Tammemagi CM, Liu G, Peacock S, Shepherd FA, Goffin J, Goss G, Nicholas G, Tremblay A, Johnston M, Martel S, Laberge F, Bhatia R, ... ... Tsao MS, et al. Plasma pro-surfactant protein B and lung function decline in smokers. The European Respiratory Journal. 45: 1037-45. PMID 25614175 DOI: 10.1183/09031936.00184214  0.336
2015 Starmans MH, Pintilie M, Chan-Seng-Yue M, Moon NC, Haider S, Nguyen F, Lau SK, Liu N, Kasprzyk A, Wouters BG, Der SD, Shepherd FA, Jurisica I, Penn LZ, Tsao MS, et al. Integrating RAS status into prognostic signatures for adenocarcinomas of the lung. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1477-86. PMID 25609067 DOI: 10.1158/1078-0432.Ccr-14-1749  0.391
2015 Tsao MS, Shepherd FA, Brambilla E, Soria JC. Predictive versus prognostic value of lung adenocarcinoma classification Journal of Clinical Oncology. 33: 225-226. PMID 25488962 DOI: 10.1200/Jco.2014.58.7022  0.397
2015 Jao K, Tomasini P, Kamel-Reid S, Tsao MS, Korpanty GJ, Mascaux C, Liu G, Leighl NB, Feld R, Bradbury PA, Ennis M, Shepherd FA. Prognostic effect of single versus multiple somatic mutations in non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 33: 7521-7521. DOI: 10.1200/Jco.2015.33.15_Suppl.7521  0.327
2015 Lohse I, Cao P, Ibrahimov E, Tsao M, Hedley DW. Abstract A106: BRCA mutation sensitizes pancreatic tumors to treatment with cisplatin Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A106  0.382
2015 Lohse I, Rasowski J, Cao P, Pintilie M, Do T, Ibrahimov E, Tsao M, Hill RP, Hedley DW. Abstract A102: Combination treatment with hypoxia-activated prodrug TH-302 and radiation reduce pancreatic tumor initiating cells and tumor growth in patient-derived xenografts Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A102  0.341
2015 Zhang W, Taylor P, Li L, Wei Y, Tong J, Ignatchenko V, Pham N, Kislinger T, Tsao M, Moran M. Abstract 1822: Proteome signatures distinguish lung cancer subtypes, define metabolism states, and have prognostic impact Cancer Research. 75: 1822-1822. DOI: 10.1158/1538-7445.Am2015-1822  0.485
2015 Hai J, Sakashita S, Allo G, Ludkovski O, Ng C, Shepherd FA, Tsao MS. Inhibiting MDM2-p53 interaction suppresses tumor growth in patient-derived non-small cell lung cancer xenograft models Journal of Thoracic Oncology. 10: 1172-1180. DOI: 10.1097/JTO.0000000000000584  0.345
2014 Zhu CQ, Tsao MS. Prognostic markers in lung cancer: is it ready for prime time? Translational Lung Cancer Research. 3: 149-58. PMID 25806294 DOI: 10.3978/J.Issn.2218-6751.2014.06.09  0.455
2014 Van de Laar E, Clifford M, Hasenoeder S, Kim BR, Wang D, Lee S, Paterson J, Vu NM, Waddell TK, Keshavjee S, Tsao MS, Ailles L, Moghal N. Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respiratory Research. 15: 160. PMID 25551685 DOI: 10.1186/S12931-014-0160-8  0.41
2014 Ellis PM, Shepherd FA, Millward M, Perrone F, Seymour L, Liu G, Sun S, Cho BC, Morabito A, Leighl NB, Stockler MR, Lee CW, Wierzbicki R, Cohen V, Blais N, ... ... Tsao MS, et al. Dacomitinib compared with placebo in pretreated patients with advanced or metastatic non-small-cell lung cancer (NCIC CTG BR.26): a double-blind, randomised, phase 3 trial. The Lancet. Oncology. 15: 1379-88. PMID 25439692 DOI: 10.1016/S1470-2045(14)70472-3  0.355
2014 Li L, Wei Y, To C, Zhu CQ, Tong J, Pham NA, Taylor P, Ignatchenko V, Ignatchenko A, Zhang W, Wang D, Yanagawa N, Li M, Pintilie M, Liu G, ... ... Tsao MS, et al. Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact. Nature Communications. 5: 5469. PMID 25429762 DOI: 10.1038/Ncomms6469  0.307
2014 Tsao MS, Travis WD, Brambilla E, Nicholson AG, Noguchi M, Hirsch FR. Forty years of the international association for study of lung cancer pathology committee. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1740-9. PMID 25393791 DOI: 10.1097/Jto.0000000000000356  0.443
2014 Radulovich N, Leung L, Ibrahimov E, Navab R, Sakashita S, Zhu CQ, Kaufman E, Lockwood WW, Thu KL, Fedyshyn Y, Moffat J, Lam WL, Tsao MS. Coiled-coil domain containing 68 (CCDC68) demonstrates a tumor-suppressive role in pancreatic ductal adenocarcinoma. Oncogene. PMID 25381825 DOI: 10.1038/Onc.2014.357  0.578
2014 Golaraei A, Cisek R, Krouglov S, Navab R, Niu C, Sakashita S, Yasufuku K, Tsao MS, Wilson BC, Barzda V. Characterization of collagen in non-small cell lung carcinoma with second harmonic polarization microscopy. Biomedical Optics Express. 5: 3562-7. PMID 25360372 DOI: 10.1364/Boe.5.003562  0.413
2014 Tsoref D, Welch S, Lau S, Biagi J, Tonkin K, Martin LA, Ellard S, Ghatage P, Elit L, Mackay HJ, Allo G, Tsao MS, Kamel-Reid S, Eisenhauer EA, Oza AM. Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer. Gynecologic Oncology. 135: 184-9. PMID 25173583 DOI: 10.1016/J.Ygyno.2014.06.033  0.388
2014 Thunnissen E, Noguchi M, Aisner S, Beasley MB, Brambilla E, Chirieac LR, Chung JH, Dacic S, Geisinger KR, Hirsch FR, Ishikawa Y, Kerr KM, Lantejoul S, Matsuno Y, Minami Y, ... ... Tsao MS, et al. Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1354-62. PMID 25122431 DOI: 10.1097/JTO.0000000000000264  0.354
2014 Cutz JC, Craddock KJ, Torlakovic E, Brandao G, Carter RF, Bigras G, Deschenes J, Izevbaye I, Xu Z, Greer W, Yatabe Y, Ionescu D, Karsan A, Jung S, Fraser RS, ... ... Tsao MS, et al. Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1255-63. PMID 25122422 DOI: 10.1097/Jto.0000000000000239  0.389
2014 Cressman S, Lam S, Tammemagi MC, Evans WK, Leighl NB, Regier DA, Bolbocean C, Shepherd FA, Tsao MS, Manos D, Liu G, Atkar-Khattra S, Cromwell I, Johnston MR, Mayo JR, et al. Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1449-58. PMID 25105438 DOI: 10.1097/Jto.0000000000000283  0.347
2014 Kim L, Tsao MS. Tumour tissue sampling for lung cancer management in the era of personalised therapy: what is good enough for molecular testing? The European Respiratory Journal. 44: 1011-22. PMID 25102961 DOI: 10.1183/09031936.00197013  0.327
2014 Shiau CJ, Babwah JP, da Cunha Santos G, Sykes JR, Boerner SL, Geddie WR, Leighl NB, Wei C, Kamel-Reid S, Hwang DM, Tsao MS. Sample features associated with success rates in population-based EGFR mutation testing. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 947-56. PMID 24922009 DOI: 10.1097/Jto.0000000000000196  0.422
2014 Azad AK, Qiu X, Boyd K, Kuang Q, Emami M, Perera N, Palepu P, Patel D, Chen Z, Cheng D, Feld R, Leighl NB, Shepherd FA, Tsao MS, Xu W, et al. A genetic sequence variant (GSV) at susceptibility loci of 5p15.33 (TERT-CLPTM1L) is associated with survival outcome in locally advanced and metastatic non-small-cell lung cancer (NSCLC). Lung Cancer (Amsterdam, Netherlands). 84: 289-94. PMID 24679952 DOI: 10.1016/J.Lungcan.2014.03.008  0.451
2014 Cooper W, Fox S, O'Toole S, Morey A, Frances G, Pavlakis N, O'Byrne K, Dettrick A, Leong T, Rathi V, Spagnolo D, Hemmings C, Singh M, Moffat D, Tsao MS, et al. National Working Group Meeting on ALK diagnostics in lung cancer. Asia-Pacific Journal of Clinical Oncology. 10: 11-7. PMID 24673736 DOI: 10.1111/Ajco.12190  0.458
2014 Boyer M, Tsao MS, Jänne P, Ramalingam S, Pitman Lowenthal S, Alam M. Preparing for tomorrow: molecular diagnostics and the changing nonsmall cell lung cancer landscape. Asia-Pacific Journal of Clinical Oncology. 10: 2-10. PMID 24673735 DOI: 10.1111/Ajco.12189  0.467
2014 Petschnigg J, Groisman B, Kotlyar M, Taipale M, Zheng Y, Kurat CF, Sayad A, Sierra JR, Mattiazzi Usaj M, Snider J, Nachman A, Krykbaeva I, Tsao MS, Moffat J, Pawson T, et al. The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nature Methods. 11: 585-92. PMID 24658140 DOI: 10.1038/Nmeth.2895  0.335
2014 Djalalov S, Beca J, Hoch JS, Krahn M, Tsao MS, Cutz JC, Leighl NB. Cost effectiveness of EML4-ALK fusion testing and first-line crizotinib treatment for patients with advanced ALK-positive non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1012-9. PMID 24567430 DOI: 10.1200/JCO.2013.53.1186  0.301
2014 Organ SL, Hai J, Radulovich N, Marshall CB, Leung L, Sasazuki T, Shirasawa S, Zhu CQ, Navab R, Ikura M, Tsao MS. p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line. Plos One. 9: e86103. PMID 24465899 DOI: 10.1371/Journal.Pone.0086103  0.546
2014 Zhang W, Wei Y, Ignatchenko V, Li L, Sakashita S, Pham NA, Taylor P, Tsao MS, Kislinger T, Moran MF. Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches. Proteomics. 14: 795-803. PMID 24453208 DOI: 10.1002/Pmic.201300382  0.314
2014 Bitanihirwe BKY, Meerang M, Friess M, Soltermann A, Frischknecht L, Thies S, Felley-Bosco E, Tsao MS, Allo G, De Perrot M, Seifert B, Moch H, Stahel R, Weder W, Opitz I. PI3K/mTOR signaling in mesothelioma patients treated with induction chemotherapy followed by extrapleural pneumonectomy Journal of Thoracic Oncology. 9: 239-247. PMID 24419422 DOI: 10.1097/Jto.0000000000000055  0.35
2014 Field JK, Aberle DR, Altorki N, Baldwin DR, Dresler C, Duffy SW, Goldstraw P, Hirsch FR, Pedersen JH, de Koning HJ, Mulshine JL, Sullivan DC, Tsao MS, Travis WD. The International Association Study Lung Cancer (IASLC) Strategic Screening Advisory Committee (SSAC) response to the USPSTF recommendations. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 141-3. PMID 24419409 DOI: 10.1097/Jto.0000000000000060  0.383
2014 Der SD, Sykes J, Pintilie M, Zhu CQ, Strumpf D, Liu N, Jurisica I, Shepherd FA, Tsao MS. Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 59-64. PMID 24305008 DOI: 10.1097/Jto.0000000000000042  0.462
2014 Laurie SA, Goss GD, Shepherd FA, Reaume MN, Nicholas G, Philip L, Wang L, Schwock J, Hirsh V, Oza A, Tsao MS, Wright JJ, Leighl NB. A phase II trial of saracatinib, an inhibitor of src kinases, in previously-treated advanced non-small-cell lung cancer: the princess margaret hospital phase II consortium. Clinical Lung Cancer. 15: 52-7. PMID 24169259 DOI: 10.1016/J.Cllc.2013.08.001  0.396
2014 Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, ... ... Tsao MS, et al. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene. 33: 4464-73. PMID 24096489 DOI: 10.1038/Onc.2013.396  0.49
2014 Chiu JW, Bedard PL, Roehrl MH, Serra S, Kryzanowska MK, Knox JJ, Mackay H, Hedley DW, Moore MJ, Liu G, Dhani NC, Kamel-Reid S, Torlakovic E, Wang T, Tsao M, et al. Molecular profiling of patients (pts) with advanced colorectal cancer (CRC): Princess Margaret Cancer Centre experience. Journal of Clinical Oncology. 32: 459-459. DOI: 10.1200/Jco.2014.32.3_Suppl.459  0.343
2014 Deschenes J, Cutz J, Bigras G, Craddock KJ, Torlakovic E, Izevbaye I, Gaspo R, Tsao M. Canadian ALK (CALK): A multicenter, prospective study of concurrent ALK immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) in NSCLC. Journal of Clinical Oncology. 32: 8070-8070. DOI: 10.1200/Jco.2014.32.15_Suppl.8070  0.353
2014 Zer A, Cutz J, Sekhon HS, Hwang DM, Sit C, Binnie M, Brade AM, Chung T, Kamel-Reid S, Narinder P, Tsao M, Waddell TK, Santos GdC, Patel M, Carter RF, et al. A targeted intervention to improve awareness to molecular testing in NSCLC. Journal of Clinical Oncology. 32: 6547-6547. DOI: 10.1200/Jco.2014.32.15_Suppl.6547  0.313
2014 Brana I, She D, Chau NG, Pham N, Kim L, Sakashita S, Ng C, Zhu C, Razak ARA, Chen E, Wang L, Perz-Ordonez B, Winquist E, Hotte SJ, Tsao M, et al. Preoperative window-of-opportunity (WOO) study of dacomitinib (Dac) in patients (Pts) with resectable oral cavity squamous cell carcinoma (OCC): Generation of a gene expression signature (DGS) as a predictor of Dac activity. Journal of Clinical Oncology. 32: 6041-6041. DOI: 10.1200/Jco.2014.32.15_Suppl.6041  0.357
2014 Navab R, Hao J, Sakashita S, Wang D, Pintilier M, Wang Y, Zhu C, Venkat K, Jurisica I, Tsao M. Abstract 4800: Heterogeneity of cancer associated fibroblasts in non-small cell lung cancer is defined by the level of collagen gel contraction activity Cancer Research. 74: 4800-4800. DOI: 10.1158/1538-7445.Am2014-4800  0.513
2014 Joseph J, Radulovich N, Tsao M. Abstract 1553: Rho guanine nucleotide exchange factor (ARHGEF) 10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma Cancer Research. 74: 1553-1553. DOI: 10.1158/1538-7445.Am2014-1553  0.45
2014 Stewart EL, Mascaux C, Shakashita S, Panchal D, Wang D, Li M, Pham N, Leighl N, Liu G, Shepherd FA, Tsao M. Abstract 1184: Modeling mechanisms of resistance of epidermal growth factor receptor (EGFR) mutations to targeted drugs through patient-derived xenografts (PDX) of non-small cell lung cancer (NSCLC) Cancer Research. 74: 1184-1184. DOI: 10.1158/1538-7445.Am2014-1184  0.421
2013 Leung L, Radulovich N, Zhu CQ, Wang D, To C, Ibrahimov E, Tsao MS. Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis. Plos One. 8: e84366. PMID 24386371 DOI: 10.1371/Journal.Pone.0084366  0.583
2013 Thunnissen E, Beliën JA, Kerr KM, Chung JH, Flieder DB, Noguchi M, Yatabe Y, Hwang DM, Lely RJ, Hartemink KJ, Meijer-Jorna LB, Tsao MS. In compressed lung tissue microscopic sections of adenocarcinoma in situ may mimic papillary adenocarcinoma. Archives of Pathology & Laboratory Medicine. 137: 1792-7. PMID 24283861 DOI: 10.5858/Arpa.2012-0613-Sa  0.359
2013 Craddock KJ, Ludkovski O, Sykes J, Shepherd FA, Tsao MS. Prognostic value of fibroblast growth factor receptor 1 gene locus amplification in resected lung squamous cell carcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 1371-7. PMID 24077455 DOI: 10.1097/Jto.0B013E3182A46Fe9  0.404
2013 Dokouhaki P, Schuh NW, Joe B, Allen CA, Der SD, Tsao MS, Zhang L. NKG2D regulates production of soluble TRAIL by ex vivo expanded human γδ T cells. European Journal of Immunology. 43: 3175-82. PMID 24019170 DOI: 10.1002/Eji.201243150  0.409
2013 McWilliams A, Tammemagi MC, Mayo JR, Roberts H, Liu G, Soghrati K, Yasufuku K, Martel S, Laberge F, Gingras M, Atkar-Khattra S, Berg CD, Evans K, Finley R, Yee J, ... ... Tsao MS, et al. Probability of cancer in pulmonary nodules detected on first screening CT. The New England Journal of Medicine. 369: 910-9. PMID 24004118 DOI: 10.1056/Nejmoa1214726  0.339
2013 Goss GD, O'Callaghan C, Lorimer I, Tsao MS, Masters GA, Jett J, Edelman MJ, Lilenbaum R, Choy H, Khuri F, Pisters K, Gandara D, Kernstine K, Butts C, Noble J, et al. Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3320-6. PMID 23980091 DOI: 10.1200/Jco.2013.51.1816  0.341
2013 Coe BP, Thu KL, Aviel-Ronen S, Vucic EA, Gazdar AF, Lam S, Tsao MS, Lam WL. Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer. Plos One. 8: e71670. PMID 23967231 DOI: 10.1371/journal.pone.0071670  0.356
2013 John T, Starmans MH, Chen YT, Russell PA, Barnett SA, White SC, Mitchell PL, Walkiewicz M, Azad A, Lambin P, Tsao MS, Deb S, Altorki N, Wright G, Knight S, et al. The role of Cancer-Testis antigens as predictive and prognostic markers in non-small cell lung cancer. Plos One. 8: e67876. PMID 23935846 DOI: 10.1371/Journal.Pone.0067876  0.481
2013 Tsao MS, Jablons DM. Molecular prognostication of non-small cell lung cancer. Seminars in Thoracic and Cardiovascular Surgery. 25: 4-7. PMID 23800523 DOI: 10.1053/J.Semtcvs.2013.01.007  0.466
2013 Shepherd FA, Domerg C, Hainaut P, Jänne PA, Pignon JP, Graziano S, Douillard JY, Brambilla E, Le Chevalier T, Seymour L, Bourredjem A, Le Teuff G, Pirker R, Filipits M, Rosell R, ... ... Tsao MS, et al. Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2173-81. PMID 23630215 DOI: 10.1200/JCO.2012.48.1390  0.336
2013 Martin P, Leighl NB, Tsao MS, Shepherd FA. KRAS mutations as prognostic and predictive markers in non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 530-42. PMID 23524403 DOI: 10.1097/Jto.0B013E318283D958  0.444
2013 Friboulet L, Olaussen KA, Pignon JP, Shepherd FA, Tsao MS, Graziano S, Kratzke R, Douillard JY, Seymour L, Pirker R, Filipits M, André F, Solary E, Ponsonnailles F, Robin A, et al. ERCC1 isoform expression and DNA repair in non-small-cell lung cancer. The New England Journal of Medicine. 368: 1101-10. PMID 23514287 DOI: 10.1056/NEJMoa1214271  0.349
2013 Dua P, Kang HS, Hong SM, Tsao MS, Kim S, Lee DK. Alkaline phosphatase ALPPL-2 is a novel pancreatic carcinoma-associated protein. Cancer Research. 73: 1934-45. PMID 23467613 DOI: 10.1158/0008-5472.Can-12-3682  0.421
2013 Craddock KJ, Lam WL, Tsao MS. Applications of array-CGH for lung cancer. Methods in Molecular Biology (Clifton, N.J.). 973: 297-324. PMID 23412798 DOI: 10.1007/978-1-62703-281-0_19  0.432
2013 Yanagawa N, Wang A, Kohler D, Santos Gda C, Sykes J, Xu J, Pintilie M, Tsao MS. Human papilloma virus genome is rare in North American non-small cell lung carcinoma patients. Lung Cancer (Amsterdam, Netherlands). 79: 215-20. PMID 23254264 DOI: 10.1016/J.Lungcan.2012.11.018  0.353
2013 Xu J, Knox JJ, Ibrahimov E, Chen E, Serra S, Tsao M, Cao P, Vines D, Green DE, Metran-Nascente C, McNamara MG, Hedley DW. Sequence dependence of MEK inhibitor AZD6244 combined with gemcitabine for the treatment of biliary cancer Clinical Cancer Research. 19: 118-127. PMID 23091117 DOI: 10.1158/1078-0432.Ccr-12-2557  0.376
2013 Huang S, Ewing AL, Reitze NJ, Uihlein AH, Wang D, Gabrin MJ, Keating KE, Mulligan J, Wilson C, Davison T, McKenzie S, Tsao M, Shepherd FA, Brower SL. Performance of a prognostic genomic signature for early-stage NSCLC in matched fresh frozen and RNA-stabilized tissue. Journal of Clinical Oncology. 31: 7532-7532. DOI: 10.1200/Jco.2013.31.15_Suppl.7532  0.333
2013 Sacher AG, Lara-Guerra H, Waddell TK, Kim L, Chen Z, Salvarrey A, Darling G, Yasufuku K, Keshavjee S, de Perrot M, Shepherd FA, Liu G, Tsao MS, Leighl NB. Surgery for early non-small cell lung cancer with preoperative erlotinib (SELECT): A correlative biomarker study. Journal of Clinical Oncology. 31: 7516-7516. DOI: 10.1200/Jco.2013.31.15_Suppl.7516  0.317
2013 Bedard PL, Oza AM, Tsao M, Leighl NB, Shepherd FA, Chen EX, Tannock I, Krzyzanowska MK, Dhani NC, Clarke B, Berman HK, Serra S, Craddock KJ, Chadwick D, Zhang T, et al. Princess Margaret Cancer Centre (PMCC) Integrated Molecular Profiling in Advanced Cancers Trial (IMPACT) using genotyping and targeted next-generation sequencing (NGS). Journal of Clinical Oncology. 31: 11002-11002. DOI: 10.1200/Jco.2013.31.15_Suppl.11002  0.386
2013 Yoshimoto M, Ludkovski O, Good J, Gooding RJ, McGowan-Jordan J, Boag A, Evans A, Tsao M, Nuin P, Squire JA. Abstract 63: Incorporation of flanking probes reduces truncation losses for fluorescence in situ hybridization analysis of recurrent genomic deletions in tumor sections. Cancer Research. 73: 63-63. DOI: 10.1158/1538-7445.Am2013-63  0.346
2013 Hai J, Tsao M. Abstract 1979: Tripartite motif 14 (TRIM14) is a putative tumor suppressor gene in non-small-cell lung cancer. Cancer Research. 73: 1979-1979. DOI: 10.1158/1538-7445.Am2013-1979  0.509
2013 Lohse I, Cao P, Do T, Ibrahimov E, Tsao M, Hedley DW. Abstract B282: The PLK-4 inhibitor CFI-400945 reduces tumor growth in patient-derived pancreatic xenografts. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B282  0.387
2013 Djalalov S, Beca J, Hoch J, Krahn M, Tsao M, Cutz J, Leighl N. Cost-Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients with Advanced ALK Positive Non-Small Cell Lung Cancer in a Publicly Funded System (Ontario, Canada) Value in Health. 16: A410. DOI: 10.1016/J.JVAL.2013.08.503  0.313
2013 Djalalov S, Hoch J, Beca J, Krahn M, Tsao M, Cutz J, Leighl N. Cost-Effectiveness Of Eml4-Alk Fusion Testing In Combination With Crizotinib Treatment For Patients With Advanced Non-Small Cell Lung Cancer Living In Ontario Value in Health. 16: A142. DOI: 10.1016/J.Jval.2013.03.696  0.316
2012 Starmans MH, Pintilie M, John T, Der SD, Shepherd FA, Jurisica I, Lambin P, Tsao MS, Boutros PC. Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies. Genome Medicine. 4: 84. PMID 23146350 DOI: 10.1186/Gm385  0.388
2012 Carbone DP, Ding K, Roder H, Grigorieva J, Roder J, Tsao MS, Seymour L, Shepherd FA. Prognostic and predictive role of the VeriStrat plasma test in patients with advanced non-small-cell lung cancer treated with erlotinib or placebo in the NCIC Clinical Trials Group BR.21 trial. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1653-60. PMID 23059783 DOI: 10.1097/Jto.0B013E31826C1155  0.346
2012 Leung L, Radulovich N, Zhu CQ, Organ S, Bandarchi B, Pintilie M, To C, Panchal D, Tsao MS. Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma. Plos One. 7: e46677. PMID 23056397 DOI: 10.1371/Journal.Pone.0046677  0.548
2012 Yanagawa N, Leduc C, Kohler D, Saieg MA, John T, Sykes J, Yoshimoto M, Pintilie M, Squire J, Shepherd FA, Tsao MS. Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1513-21. PMID 22982652 DOI: 10.1097/Jto.0B013E3182641D4F  0.442
2012 da Cunha Santos G, Lai SW, Saieg MA, Geddie WR, Pintilie M, Tsao MS, Boerner SL, Hwang D. Cyto-histologic agreement in pathologic subtyping of non small cell lung carcinoma: review of 602 fine needle aspirates with follow-up surgical specimens over a nine year period and analysis of factors underlying failure to subtype. Lung Cancer (Amsterdam, Netherlands). 77: 501-6. PMID 22656670 DOI: 10.1016/J.Lungcan.2012.05.091  0.415
2012 Lockwood WW, Wilson IM, Coe BP, Chari R, Pikor LA, Thu KL, Solis LM, Nunez MI, Behrens C, Yee J, English J, Murray N, Tsao MS, Minna JD, Gazdar AF, et al. Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development. Plos One. 7: e37775. PMID 22629454 DOI: 10.1371/journal.pone.0037775  0.46
2012 John T, Yanagawa N, Kohler D, Craddock KJ, Bandarchi-Chamkhaleh B, Pintilie M, Sykes J, To C, Li M, Panchal D, Chen W, Shepherd FA, Tsao MS. Characterization of lymphomas developing in immunodeficient mice implanted with primary human non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1101-8. PMID 22617243 DOI: 10.1097/Jto.0B013E3182519D4D  0.438
2012 Cuffe S, Bourredjem A, Graziano S, Pignon JP, Domerg C, Ezzalfani M, Seymour L, Strevel E, Burkes R, Capelletti M, Jänne PA, Tsao MS, Shepherd FA. A pooled exploratory analysis of the effect of tumor size and KRAS mutations on survival benefit from adjuvant platinum-based chemotherapy in node-negative non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 963-72. PMID 22588152 DOI: 10.1097/Jto.0B013E31824Fe9E6  0.367
2012 Iakovlev V, Siegel ER, Tsao MS, Haun RS. Expression of kallikrein-related peptidase 7 predicts poor prognosis in patients with unresectable pancreatic ductal adenocarcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 1135-42. PMID 22573795 DOI: 10.1158/1055-9965.Epi-11-1079  0.318
2012 Hembrough T, Thyparambil S, Liao WL, Darfler MM, Abdo J, Bengali KM, Taylor P, Tong J, Lara-Guerra H, Waddell TK, Moran MF, Tsao MS, Krizman DB, Burrows J. Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue. Clinical Proteomics. 9: 5. PMID 22554165 DOI: 10.1186/1559-0275-9-5  0.356
2012 Fehringer G, Liu G, Pintilie M, Sykes J, Cheng D, Liu N, Chen Z, Seymour L, Der SD, Shepherd FA, Tsao MS, Hung RJ. Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumor tissue. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 1097-104. PMID 22539604 DOI: 10.1158/1055-9965.Epi-11-1123-T  0.437
2012 Kamel-Reid S, Chong G, Ionescu DN, Magliocco AM, Spatz A, Tsao M, Weng X, Young S, Zhang T, Soulieres D. EGFR tyrosine kinase mutation testing in the treatment of non-small-cell lung cancer. Current Oncology (Toronto, Ont.). 19: e67-74. PMID 22514499 DOI: 10.3747/Co.19.862  0.421
2012 Allibhai Z, Cho BCJ, Taremi M, Atallah S, Hope A, Hwang D, Keshavjee S, Tsao M, Yasufuku K, Kim S, Bezjak A. Surgical salvage following stereotactic body radiotherapy for early-stage NSCLC European Respiratory Journal. 39: 1039-1042. PMID 22467727 DOI: 10.1183/09031936.00075811  0.316
2012 Hai J, Zhu CQ, Bandarchi B, Wang YH, Navab R, Shepherd FA, Jurisica I, Tsao MS. L1 cell adhesion molecule promotes tumorigenicity and metastatic potential in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1914-24. PMID 22307136 DOI: 10.1158/1078-0432.Ccr-11-2893  0.485
2012 Dubinski W, Leighl NB, Tsao MS, Hwang DM. Ancillary testing in lung cancer diagnosis. Pulmonary Medicine. 2012: 249082. PMID 22263108 DOI: 10.1155/2012/249082  0.324
2012 Lara-Guerra H, Chung CT, Schwock J, Pintilie M, Hwang DM, Leighl NB, Waddell TK, Tsao MS. Histopathological and immunohistochemical features associated with clinical response to neoadjuvant gefitinib therapy in early stage non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 76: 235-41. PMID 22112291 DOI: 10.1016/J.Lungcan.2011.10.020  0.446
2012 Organ SL, Sierra JR, Tsao M. Therapeutic potential of c-MET inhibitors: background and clinical data Clinical Investigation. 2: 301-315. DOI: 10.4155/Cli.12.11  0.348
2012 Azad AK, Qiu X, Cuffe S, Qiu X, Boyd K, Kuang Q, Emami M, Perera N, Palepu PR, Patel D, Chen Z, Cheng D, Feld R, Leighl NB, Shepherd FA, ... Tsao MS, et al. Genetic sequence variant (GSV) in TERT-CLPTM1L (5p15.33 locus) and survival in platinum-treated stage-IV non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 30: 1535-1535. DOI: 10.1200/Jco.2012.30.15_Suppl.1535  0.345
2012 Ibrahimov E, Pham N, Meng F, Sukhram M, Chadwick D, Serra S, Shaw P, Rowsell C, Law C, McPherson J, Gallinger S, Tsao M. Abstract B91: Primary tumor xenograft establishment from pancreatic resection specimens. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B91  0.381
2012 Leung L, Radulovich N, Park CJ, To C, Ibrahimov E, Bandarchi B, Tsao M. Abstract B102: Expression of KRASG12V and loss of Smad4 contribute to pancreatic duct cell carcinogenesis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B102  0.416
2012 Begley KN, Mukhopadhyay D, Petersen GM, Protopopov A, Thayer S, Chin L, Ibrahimov E, Shaw P, Hudson T, Gallinger S, Tsao M, Stein L, McPherson JD, Muthuswamy L, Beck T, et al. Abstract A9: The pancreatic ductal adenocarcinoma project at the Ontario Institute for Cancer Research. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A9  0.357
2012 Moran MF, To C, Wei Y, Li L, Taylor P, Ignatchenko V, Strumpf D, Tong J, Pham N, Jurisica I, Muthuswamy L, Kislinger T, Tsao M. Abstract 5127: Characterization of lung cancers by integrated genomic and proteomic analysis Cancer Research. 72: 5127-5127. DOI: 10.1158/1538-7445.Am2012-5127  0.454
2012 To C, Strumpf D, Panchal D, Li M, Pham N, Xie W, Yanagawa N, Bandarchi B, Chui MH, Der S, Shepherd FA, Kislinger T, Moran M, Jurisica I, Muthuswamy L, ... Tsao M, et al. Abstract 5069: Genomic profiles of primary non-small cell lung cancer (NSCLC) xenograft tumors identify distinct gene signatures associated with histological subtypes Cancer Research. 72: 5069-5069. DOI: 10.1158/1538-7445.Am2012-5069  0.489
2012 Wong S, Kotlyar M, Strumpf D, Cercone N, Shepherd FA, Tsao M, Jurisica I. Abstract 4912: Systematic, comparative network analysis on non-small cell lung cancer Cancer Research. 72: 4912-4912. DOI: 10.1158/1538-7445.Am2012-4912  0.46
2012 Wei Y, Taylor P, Tong J, Pham N, Li M, Panchal D, To C, Chui MH, Tsao M, Kislinger T, Moran MF. Abstract 4805: Distinctive phospho-proteome signatures in non-small cell lung carcinoma tumors Cancer Research. 72: 4805-4805. DOI: 10.1158/1538-7445.Am2012-4805  0.411
2012 Fehringer G, Liu G, Pintilie M, Sykes J, Liu N, Cheng D, Chen Z, Seymour L, Der SD, Shepherd FA, Tsao M, Hung RJ. Abstract 4210: Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumor tissue Cancer Research. 72: 4210-4210. DOI: 10.1158/1538-7445.Am2012-4210  0.443
2012 Sierra R, Chang A, Moffat J, Neel BG, Tsao M. Abstract B34: Overcoming resistance to EGFR-Tyrosine Kinase Inhibitor therapy in non-small cell lung cancer Clinical Cancer Research. 18: B34-B34. DOI: 10.1158/1538-7445.Am2012-1232  0.448
2012 Thu KL, Hubaux R, Aviel-Ronen S, MacAulay CE, Tsao M, Lam S, Lam WL, Coe BP. Abstract A29: Genomic alteration of E2F/Rb activates EZH2 in small cell lung cancer Clinical Cancer Research. 18: A29-A29. DOI: 10.1158/1078-0432.12Aacriaslc-A29  0.459
2012 Janne PA, Shepherd FA, Domerg C, Teuff GL, Kratzke R, Hainaut P, Pignon J, Rosell R, Soria J, Tsao M. Prognostic and Predictive Values of KRAS in EGFR-Based Subgroups and Combined With p53 in Completely Resected Non-Small Cell Lung Cancer (NSCLC): A Lace-Bio Study Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)32761-7  0.347
2011 Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, ... ... Tsao MS, et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discovery. 1: 78-89. PMID 22328973 DOI: 10.1158/2159-8274.Cd-11-0005  0.392
2011 Organ SL, Tsao MS. An overview of the c-MET signaling pathway. Therapeutic Advances in Medical Oncology. 3: S7-S19. PMID 22128289 DOI: 10.1177/1758834011422556  0.331
2011 Sierra JR, Tsao MS. c-MET as a potential therapeutic target and biomarker in cancer. Therapeutic Advances in Medical Oncology. 3: S21-35. PMID 22128285 DOI: 10.1177/1758834011422557  0.372
2011 Starczynowski DT, Lockwood WW, Deléhouzée S, Chari R, Wegrzyn J, Fuller M, Tsao MS, Lam S, Gazdar AF, Lam WL, Karsan A. TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. The Journal of Clinical Investigation. 121: 4095-105. PMID 21911935 DOI: 10.1172/Jci58818  0.379
2011 Salto-Tellez M, Tsao MS, Shih JY, Thongprasert S, Lu S, Chang GC, Au JS, Chou TY, Lee JS, Shi YK, Radzi A, Kang JH, Kim SW, Tan SY, Yang JC. Clinical and testing protocols for the analysis of epidermal growth factor receptor mutations in East Asian patients with non-small cell lung cancer: a combined clinical-molecular pathological approach. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 1663-9. PMID 21869714 DOI: 10.1097/JTO.0b013e318227816a  0.334
2011 Oza AM, Elit L, Tsao MS, Kamel-Reid S, Biagi J, Provencher DM, Gotlieb WH, Hoskins PJ, Ghatage P, Tonkin KS, Mackay HJ, Mazurka J, Sederias J, Ivy P, Dancey JE, et al. Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3278-85. PMID 21788564 DOI: 10.1200/Jco.2010.34.1578  0.379
2011 Ellis PM, Blais N, Soulieres D, Ionescu DN, Kashyap M, Liu G, Melosky B, Reiman T, Romeo P, Shepherd FA, Tsao MS, Leighl NB. A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 1379-91. PMID 21709590 DOI: 10.1097/Jto.0B013E318220Cb8E  0.482
2011 Organ SL, Tong J, Taylor P, St-Germain JR, Navab R, Moran MF, Tsao MS. Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer. Journal of Proteome Research. 10: 3200-11. PMID 21609022 DOI: 10.1021/Pr200238T  0.36
2011 Navab R, Strumpf D, Bandarchi B, Zhu CQ, Pintilie M, Ramnarine VR, Ibrahimov E, Radulovich N, Leung L, Barczyk M, Panchal D, To C, Yun JJ, Der S, Shepherd FA, ... ... Tsao MS, et al. Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 7160-5. PMID 21474781 DOI: 10.1073/Pnas.1014506108  0.65
2011 Radulovich N, Leung L, Tsao MS. Modified gateway system for double shRNA expression and Cre/lox based gene expression. Bmc Biotechnology. 11: 24. PMID 21418658 DOI: 10.1186/1472-6750-11-24  0.524
2011 Allen TD, Zhu CQ, Jones KD, Yanagawa N, Tsao MS, Bishop JM. Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer. Cancer Research. 71: 2212-21. PMID 21406400 DOI: 10.1158/0008-5472.Can-10-3590  0.487
2011 Chau NG, Perez-Ordonez B, Zhang K, Pham NA, Ho J, Zhang T, Ludkovski O, Wang L, Chen EX, Tsao MS, Kamel-Reid S, Siu LL. The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Head & Neck Oncology. 3: 11. PMID 21352589 DOI: 10.1186/1758-3284-3-11  0.353
2011 Tsao MS, Sakurada A, Ding K, Aviel-Ronen S, Ludkovski O, Liu N, Le Maître A, Gandara D, Johnson DH, Rigas JR, Seymour L, Shepherd FA. Prognostic and predictive value of epidermal growth factor receptor tyrosine kinase domain mutation status and gene copy number for adjuvant chemotherapy in non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 139-47. PMID 21107284 DOI: 10.1097/JTO.0b013e3181fd83a4  0.352
2011 John T, Kohler D, Pintilie M, Yanagawa N, Pham NA, Li M, Panchal D, Hui F, Meng F, Shepherd FA, Tsao MS. The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 134-41. PMID 21081655 DOI: 10.1158/1078-0432.Ccr-10-2224  0.486
2011 Misquitta-Ali CM, Cheng E, O'Hanlon D, Liu N, McGlade CJ, Tsao MS, Blencowe BJ. Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer. Molecular and Cellular Biology. 31: 138-50. PMID 21041478 DOI: 10.1128/MCB.00709-10  0.371
2011 da Cunha Santos G, Shepherd FA, Tsao MS. EGFR mutations and lung cancer. Annual Review of Pathology. 6: 49-69. PMID 20887192 DOI: 10.1146/annurev-pathol-011110-130206  0.318
2011 Wei Y, Tong J, Taylor P, Strumpf D, Ignatchenko V, Pham NA, Yanagawa N, Liu G, Jurisica I, Shepherd FA, Tsao MS, Kislinger T, Moran MF. Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures. Journal of Proteome Research. 10: 161-74. PMID 20815376 DOI: 10.1021/Pr100491E  0.402
2011 D. Der S, Navab R, Ishizawa K, Tsao M. Genomic and Cellular Pathology of Lung Cancer Current Respiratory Medicine Reviews. 7: 313-322. DOI: 10.2174/157339811797189740  0.403
2011 Wei Y, Taylor P, Tong J, Strumpf D, Ignatchenko V, Pham NA, Thyparambil S, Tsao M, Kislinger T, Moran MF. Abstract 5097: Proteomic characterization of non-small cell lung cancer (NSCLC): Discovery and validation of NSCLC protein signatures and signaling networks Cancer Research. 71: 5097-5097. DOI: 10.1158/1538-7445.Am2011-5097  0.481
2011 Hembrough T, Thyparambil S, Krizman D, Darfler M, Wei Y, Taylor P, Tong J, Pham N, Jasani B, Adams R, Tsao M, Moran M, Burrows J. Abstract 4919: Multiplexed EGFR signaling pathway analysis in FFPE tissue using quantitative mass spectrometry Cancer Research. 71: 4919-4919. DOI: 10.1158/1538-7445.Am2011-4919  0.427
2011 Dhani NC, Schwock J, Cao PM, Tsao M, Hedley DW. Abstract 2431: Inhibition of metastasis through therapeutic targeting of focal adhesion kinase (FAK) in pancreatic cancer Cancer Research. 71: 2431-2431. DOI: 10.1158/1538-7445.Am2011-2431  0.43
2011 Hai J, Zhu C, Der S, Jurisica I, Tsao M. Abstract 1404: L1CAM in non-small-cell lung carcinoma Cancer Research. 71: 1404-1404. DOI: 10.1158/1538-7445.Am2011-1404  0.513
2010 da Cunha Santos G, Liu N, Tsao MS, Kamel-Reid S, Chin K, Geddie WR. Detection of EGFR and KRAS mutations in fine-needle aspirates stored on Whatman FTA cards: is this the tool for biobanking cytological samples in the molecular era? Cancer Cytopathology. 118: 450-6. PMID 21240995 DOI: 10.1002/Cncy.20102  0.435
2010 Tsao MS. Fibroblast growth factor inhibitors Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5. PMID 21102237 DOI: 10.1097/01.Jto.0000391364.18141.9D  0.471
2010 Addison CL, Ding K, Zhao H, Maître AL, Goss GD, Seymour L, Tsao MS, Shepherd FA, Bradbury PA. Plasma transforming growth factor α and amphiregulin protein levels in NCIC clinical trials group BR.21 Journal of Clinical Oncology. 28: 5247-5256. PMID 21079146 DOI: 10.1200/Jco.2010.31.0805  0.349
2010 Du J, Liu J, Smith BJ, Tsao MS, Cullen JJ. Role of Rac1-dependent NADPH oxidase in the growth of pancreatic cancer. Cancer Gene Therapy. 18: 135-43. PMID 21037555 DOI: 10.1038/Cgt.2010.64  0.396
2010 Boutros PC, Pintilie M, John T, Starmans MH, Der SD, Shepherd FA, Tsao MS, Jurisica I. Re: Gene expression-based prognostic signatures in lung cancer: ready for clinical use? Journal of the National Cancer Institute. 102: 1677-8; author reply. PMID 20921041 DOI: 10.1093/Jnci/Djq385  0.432
2010 da Cunha Santos G, Dhani N, Tu D, Chin K, Ludkovski O, Kamel-Reid S, Squire J, Parulekar W, Moore MJ, Tsao MS. Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer: National Cancer Institute of Canada Clinical Trials Group Study PA.3. Cancer. 116: 5599-607. PMID 20824720 DOI: 10.1002/cncr.25393  0.316
2010 Zhu CQ, Ding K, Strumpf D, Weir BA, Meyerson M, Pennell N, Thomas RK, Naoki K, Ladd-Acosta C, Liu N, Pintilie M, Der S, Seymour L, Jurisica I, Shepherd FA, ... Tsao MS, et al. Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4417-24. PMID 20823422 DOI: 10.1200/Jco.2009.26.4325  0.367
2010 Chari R, Lonergan KM, Pikor LA, Coe BP, Zhu CQ, Chan TH, MacAulay CE, Tsao MS, Lam S, Ng RT, Lam WL. A sequence-based approach to identify reference genes for gene expression analysis. Bmc Medical Genomics. 3: 32. PMID 20682026 DOI: 10.1186/1755-8794-3-32  0.386
2010 Lockwood WW, Chari R, Coe BP, Thu KL, Garnis C, Malloff CA, Campbell J, Williams AC, Hwang D, Zhu CQ, Buys TP, Yee J, English JC, Macaulay C, Tsao MS, et al. Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. Plos Medicine. 7: e1000315. PMID 20668658 DOI: 10.1371/Journal.Pmed.1000315  0.394
2010 Hirte H, Oza A, Swenerton K, Ellard SL, Grimshaw R, Fisher B, Tsao M, Seymour L. A phase II study of erlotinib (OSI-774) given in combination with carboplatin in patients with recurrent epithelial ovarian cancer (NCIC CTG IND.149). Gynecologic Oncology. 118: 308-12. PMID 20646751 DOI: 10.1016/J.Ygyno.2010.05.005  0.41
2010 Brenner DR, Hung RJ, Tsao MS, Shepherd FA, Johnston MR, Narod S, Rubenstein W, McLaughlin JR. Lung cancer risk in never-smokers: a population-based case-control study of epidemiologic risk factors. Bmc Cancer. 10: 285. PMID 20546590 DOI: 10.1186/1471-2407-10-285  0.331
2010 Dokouhaki P, Han M, Joe B, Li M, Johnston MR, Tsao MS, Zhang L. Adoptive immunotherapy of cancer using ex vivo expanded human γδ T cells: A new approach Cancer Letters. 297: 126-136. PMID 20537791 DOI: 10.1016/J.Canlet.2010.05.005  0.357
2010 Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... ... Tsao MS, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822  0.387
2010 Lonergan KM, Chari R, Coe BP, Wilson IM, Tsao MS, Ng RT, Macaulay C, Lam S, Lam WL. Transcriptome profiles of carcinoma-in-situ and invasive non-small cell lung cancer as revealed by SAGE. Plos One. 5: e9162. PMID 20161782 DOI: 10.1371/Journal.Pone.0009162  0.431
2010 Bradbury PA, Tu D, Seymour L, Isogai PK, Zhu L, Ng R, Mittmann N, Tsao MS, Evans WK, Shepherd FA, Leighl NB. Economic analysis: randomized placebo-controlled clinical trial of erlotinib in advanced non-small cell lung cancer. Journal of the National Cancer Institute. 102: 298-306. PMID 20160168 DOI: 10.1093/Jnci/Djp518  0.371
2010 Radulovich N, Pham NA, Strumpf D, Leung L, Xie W, Jurisica I, Tsao MS. Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma. Molecular Cancer. 9: 24. PMID 20113529 DOI: 10.1186/1476-4598-9-24  0.497
2010 Shepherd FA, Tsao MS. Epidermal growth factor receptor biomarkers in non-small-cell lung cancer: A riddle, wrapped in a mystery, inside an enigma Journal of Clinical Oncology. 28: 903-905. PMID 20100955 DOI: 10.1200/Jco.2009.26.3996  0.438
2010 Sridhar SS, Hotte SJ, Chin JL, Hudes GR, Gregg R, Trachtenberg J, Wang L, Tran-Thanh D, Pham NA, Tsao MS, Hedley D, Dancey JE, Moore MJ. A multicenter phase II clinical trial of lapatinib (GW572016) in hormonally untreated advanced prostate cancer. American Journal of Clinical Oncology. 33: 609-13. PMID 20042973 DOI: 10.1097/Coc.0B013E3181Beac33  0.34
2010 Navab R, Liu J, Seiden-Long I, Shih W, Li M, Bandarchi B, Chen Y, Lau D, Zu YF, Cescon D, Zhu CQ, Organ S, Ibrahimov E, Ohanessian D, Tsao MS. Co-overexpression of Met and hepatocyte growth factor promotes systemic metastasis in NCI-H460 non-small cell lung carcinoma cells. Neoplasia (New York, N.Y.). 11: 1292-300. PMID 20019837 DOI: 10.1593/Neo.09622  0.456
2010 Menezes RJ, Roberts HC, Paul NS, McGregor M, Chung TB, Patsios D, Weisbrod G, Herman S, Pereira A, McGregor A, Dong Z, Sitartchouk I, Boerner S, Tsao MS, Keshavjee S, et al. Lung cancer screening using low-dose computed tomography in at-risk individuals: the Toronto experience. Lung Cancer (Amsterdam, Netherlands). 67: 177-83. PMID 19427055 DOI: 10.1016/J.Lungcan.2009.03.030  0.338
2010 Organ SL, Tong J, Taylor P, Navab R, Germain JS, Moran MF, Tsao M. Abstract 5566: Phosphoproteomic profiling of Met / K-Ras signaling in colorectal cancer by label-free LTQ-Orbitrap mass spectrometry Cancer Research. 70: 5566-5566. DOI: 10.1158/1538-7445.Am10-5566  0.326
2010 Hai J, Radulovich N, Zhu C, Der SD, Jurisica I, Tsao M. Abstract 5049: Functional significance ofL1CAMin non-small cell lung cancer Cancer Research. 70: 5049-5049. DOI: 10.1158/1538-7445.Am10-5049  0.506
2010 Leung LH, Radulovich N, Tsao M. Abstract 3133: In vitro modeling of human pancreatic duct epithelial cell transformation Cancer Research. 70: 3133-3133. DOI: 10.1158/1538-7445.Am10-3133  0.417
2010 Twumasi-Ankrah P, Ding K, Seymour L, Shepherd FA, Tsao M. Abstract 1998: Asparseprognostic gene signature for stage IB and II patients with completely resected non-small cell lung cancer Cancer Research. 70: 1998-1998. DOI: 10.1158/1538-7445.Am10-1998  0.366
2010 Radulovich N, Leung L, Navab R, Thu K, Lam W, Tsao M. Abstract 1091: The role for retinoblastoma-like p130 (RBL2) and DNA damage response in human pancreatic cancer cells Cancer Research. 70: 1091-1091. DOI: 10.1158/1538-7445.Am10-1091  0.629
2009 John T, Li M, Panchal D, Hui F, Meng F, Bandarchi-Chamkhaleh B, Kohler D, Zhu C, Shepherd FA, Tsao M. Correlation of primary tumor engraftment in immune deficient mice and relapse rate in patients with early-stage non-small cell lung carcinoma (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 11082. PMID 27963173 DOI: 10.1200/Jco.2009.27.15_Suppl.11082  0.425
2009 Lara-Guerra H, Waddell TK, Salvarrey MA, Joshua AM, Chung CT, Paul N, Boerner S, Sakurada A, Ludkovski O, Ma C, Squire J, Liu G, Shepherd FA, Tsao MS, Leighl NB. Phase II study of preoperative gefitinib in clinical stage I non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 6229-36. PMID 19884551 DOI: 10.1200/Jco.2009.22.3370  0.455
2009 Zhu CQ, Pintilie M, John T, Strumpf D, Shepherd FA, Der SD, Jurisica I, Tsao MS. Understanding prognostic gene expression signatures in lung cancer. Clinical Lung Cancer. 10: 331-40. PMID 19808191 DOI: 10.3816/Clc.2009.N.045  0.429
2009 Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, ... ... Tsao MS, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics. 41: 1238-42. PMID 19801978 DOI: 10.1038/Ng.465  0.362
2009 Coate LE, John T, Tsao MS, Shepherd FA. Molecular predictive and prognostic markers in non-small-cell lung cancer. The Lancet. Oncology. 10: 1001-10. PMID 19796752 DOI: 10.1016/S1470-2045(09)70155-X  0.444
2009 Geismann C, Morscheck M, Koch D, Bergmann F, Ungefroren H, Arlt A, Tsao MS, Bachem MG, Altevogt P, Sipos B, Fölsch UR, Schäfer H, Müerköster SS. Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer. Cancer Research. 69: 4517-26. PMID 19435915 DOI: 10.1158/0008-5472.Can-08-3493  0.332
2009 Ellis PM, Morzycki W, Melosky B, Butts C, Hirsh V, Krasnoshtein F, Murray N, Shepherd FA, Soulieres D, Tsao MS, Goss G. The role of the epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small-cell lung cancer: a Canadian national consensus statement. Current Oncology (Toronto, Ont.). 16: 27-48. PMID 19229369 DOI: 10.3747/Co.V16I1.393  0.404
2009 Boutros PC, Lau SK, Pintilie M, Liu N, Shepherd FA, Der SD, Tsao MS, Penn LZ, Jurisica I. Prognostic gene signatures for non-small-cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 106: 2824-8. PMID 19196983 DOI: 10.1073/Pnas.0809444106  0.462
2009 Anraku M, Waddell TK, de Perrot M, Lewis SJ, Pierre AF, Darling GE, Johnston MR, Zener RE, Rampersaud YR, Shepherd FA, Leighl N, Bezjak A, Sun AY, Hwang DM, Tsao MS, et al. Induction chemoradiotherapy facilitates radical resection of T4 non-small cell lung cancer invading the spine. The Journal of Thoracic and Cardiovascular Surgery. 137: 441-447.e1. PMID 19185167 DOI: 10.1016/J.Jtcvs.2008.09.035  0.41
2009 Buys TP, Aviel-Ronen S, Waddell TK, Lam WL, Tsao MS. Defining genomic alteration boundaries for a combined small cell and non-small cell lung carcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 227-39. PMID 19179901 DOI: 10.1097/Jto.0B013E3181952678  0.393
2009 Tomasini R, Tsuchihara K, Tsuda C, Lau SK, Wilhelm M, Rufini A, Tsao MS, Iovanna JL, Jurisicova A, Melino G, Mak TW. TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proceedings of the National Academy of Sciences of the United States of America. 106: 797-802. PMID 19139399 DOI: 10.1073/Pnas.0812096106  0.357
2009 Sakurada A, Tsao MS. Predictive biomarkers for EGFR therapy Idrugs. 12: 34-38. PMID 19127503  0.31
2009 Lo M, Tsao MS, Hedley D, Ling V. Gene expression profiling of adenosine triphosphate-binding cassette transporters in response to K-ras activation and hypoxia in human pancreatic cancer cell cultures. Pancreas. 38: 85-93. PMID 19117087 DOI: 10.1097/Mpa.0B013E318184Aa8A  0.314
2009 Chau NG, Perez‐Ordonez B, Zhang K, Pham N, Ho J, Zhang T, Wang L, Tsao M, Kamel‐Reid S, Siu LL. Abstract B32: Retrospective correlative study between EGFRvIII, HPV, p16, c‐MET and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B32  0.374
2008 Dahele M, Hwang D, Peressotti C, Sun L, Kusano M, Okhai S, Darling G, Yaffe M, Caldwell C, Mah K, Hornby J, Ehrlich L, Raphael S, Tsao M, Behzadi A, et al. Developing a methodology for three-dimensional correlation of PET-CT images and whole-mount histopathology in non-small-cell lung cancer. Current Oncology (Toronto, Ont.). 15: 62-9. PMID 19008992 DOI: 10.3747/Co.V15I5.349  0.302
2008 Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes & Development. 22: 2677-91. PMID 18805989 DOI: 10.1101/Gad.1695308  0.329
2008 Müerköster SS, Werbing V, Koch D, Sipos B, Ammerpohl O, Kalthoff H, Tsao MS, Fölsch UR, Schäfer H. Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. International Journal of Cancer. Journal International Du Cancer. 123: 1751-60. PMID 18649362 DOI: 10.1002/Ijc.23703  0.367
2008 Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Giordano TJ, Misek DE, Chang AC, Zhu CQ, Strumpf D, Hanash S, et al. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nature Medicine. 14: 822-7. PMID 18641660 DOI: 10.1038/Nm.1790  0.315
2008 Aviel-Ronen S, Coe BP, Lau SK, da Cunha Santos G, Zhu CQ, Strumpf D, Jurisica I, Lam WL, Tsao MS. Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features. Proceedings of the National Academy of Sciences of the United States of America. 105: 10155-60. PMID 18632575 DOI: 10.1073/Pnas.0709618105  0.371
2008 Zhu CQ, da Cunha Santos G, Ding K, Sakurada A, Cutz JC, Liu N, Zhang T, Marrano P, Whitehead M, Squire JA, Kamel-Reid S, Seymour L, Shepherd FA, Tsao MS. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4268-75. PMID 18626007 DOI: 10.1200/Jco.2007.14.8924  0.379
2008 Aviel-Ronen S, Lau SK, Pintilie M, Lau D, Liu N, Tsao MS, Jothy S. Glypican-3 is overexpressed in lung squamous cell carcinoma, but not in adenocarcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 817-25. PMID 18469798 DOI: 10.1038/modpathol.2008.37  0.339
2008 Sakurada A, Lara-Guerra H, Liu N, Shepherd FA, Tsao MS. Tissue heterogeneity of EGFR mutation in lung adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 527-9. PMID 18449007 DOI: 10.1097/Jto.0B013E318168Be93  0.335
2008 Anraku M, Cunningham KS, Yun Z, Tsao MS, Zhang L, Keshavjee S, Johnston MR, de Perrot M. Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma. The Journal of Thoracic and Cardiovascular Surgery. 135: 823-9. PMID 18374762 DOI: 10.1016/J.Jtcvs.2007.10.026  0.339
2008 Radulovich N, Qian JY, Tsao MS. Human pancreatic duct epithelial cell model for KRAS transformation. Methods in Enzymology. 439: 1-13. PMID 18374152 DOI: 10.1016/S0076-6879(07)00401-6  0.379
2008 Pham NA, Schwock J, Iakovlev V, Pond G, Hedley DW, Tsao MS. Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis. Bmc Cancer. 8: 43. PMID 18254976 DOI: 10.1186/1471-2407-8-43  0.339
2008 Seiden-Long I, Navab R, Shih W, Li M, Chow J, Zhu CQ, Radulovich N, Saucier C, Tsao MS. Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells. Carcinogenesis. 29: 647-55. PMID 18192688 DOI: 10.1093/Carcin/Bgn009  0.39
2008 Salahshor S, Naidoo R, Serra S, Shih W, Tsao MS, Chetty R, Woodgett JR. Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 271-81. PMID 18084253 DOI: 10.1038/Modpathol.3800990  0.359
2007 Lau SK, Boutros PC, Pintilie M, Blackhall FH, Zhu CQ, Strumpf D, Johnston MR, Darling G, Keshavjee S, Waddell TK, Liu N, Lau D, Penn LZ, Shepherd FA, Jurisica I, ... ... Tsao MS, et al. Three-gene prognostic classifier for early-stage non small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 5562-9. PMID 18065728 DOI: 10.1200/Jco.2007.12.0352  0.353
2007 Tsao MS, Aviel-Ronen S, Ding K, Lau D, Liu N, Sakurada A, Whitehead M, Zhu CQ, Livingston R, Johnson DH, Rigas J, Seymour L, Winton T, Shepherd FA. Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 5240-7. PMID 18024870 DOI: 10.1200/Jco.2007.12.6953  0.303
2007 Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... ... Tsao MS, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358  0.304
2007 Wang C, Navab R, Iakovlev V, Leng Y, Zhang J, Tsao MS, Siminovitch K, McCready DR, Done SJ. Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion. Molecular Cancer Research : McR. 5: 1031-9. PMID 17951403 DOI: 10.1158/1541-7786.Mcr-06-0391  0.35
2007 Zhu CQ, Popova SN, Brown ER, Barsyte-Lovejoy D, Navab R, Shih W, Li M, Lu M, Jurisica I, Penn LZ, Gullberg D, Tsao MS. Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 11754-9. PMID 17600088 DOI: 10.1073/Pnas.0703040104  0.382
2007 Tsao MS, Liu G, Shepherd FA. Serum proteomic classifier for predicting response to epidermal growth factor receptor inhibitor therapy: have we built a better mousetrap? Journal of the National Cancer Institute. 99: 826-827. PMID 17551136 DOI: 10.1093/Jnci/Djk221  0.387
2007 Corson TW, Zhu CQ, Lau SK, Shepherd FA, Tsao MS, Gallie BL. KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3229-34. PMID 17545527 DOI: 10.1158/1078-0432.Ccr-07-0393  0.464
2007 Welch S, Hirte HW, Carey MS, Hotte SJ, Tsao MS, Brown S, Pond GR, Dancey JE, Oza AM. UCN-01 in combination with topotecan in patients with advanced recurrent ovarian cancer: a study of the Princess Margaret Hospital Phase II consortium. Gynecologic Oncology. 106: 305-10. PMID 17537491 DOI: 10.1016/J.Ygyno.2007.02.018  0.341
2007 Sève P, Lai R, Ding K, Winton T, Butts C, Mackey J, Dumontet C, Dabbagh L, Aviel-Ronen S, Seymour L, Whitehead M, Tsao MS, Shepherd FA, Reiman T. Class III beta-tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: analysis of NCIC JBR.10. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 994-9. PMID 17289895 DOI: 10.1158/1078-0432.Ccr-06-1503  0.434
2007 Zhu C, Popova S, Brown ER, Barsyte-Lovejoy D, Navab R, Shih W, Li M, Penn L, Gullberg D, Tsao M. P2-036: Novel mechanism of collagen-tumor cell interaction by integrin alpha-11 expression by cancer associated fibroblasts in non-small cell lung cancer cells Journal of Thoracic Oncology. 2: S496. DOI: 10.1097/01.Jto.0000283478.00088.2C  0.466
2007 Lockwood WW, Chari R, Coe BP, Buys TP, English JC, Yee J, Tsao M, MacAulay C, Lam S, Lam WL. A6-06: Integrative genomic and gene expression analysis of NSCLC identifies subtype-specific signatures of pathway disruption Journal of Thoracic Oncology. 2: S328. DOI: 10.1097/01.Jto.0000283130.99810.Bc  0.305
2006 Liu J, Costello PC, Pham NA, Pintillie M, Jabali M, Sanghera J, Tsao MS, Johnston MR. Integrin-linked kinase inhibitor KP-392 demonstrates clinical benefitsin an orthotopic human non-small cell lung cancer model Journal of Thoracic Oncology. 1: 771-779. PMID 17409959 DOI: 10.1097/01243894-200610000-00004  0.332
2006 Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS. K-ras mutations in non-small-cell lung carcinoma: a review. Clinical Lung Cancer. 8: 30-8. PMID 16870043 DOI: 10.3816/Clc.2006.N.030  0.38
2006 Lonergan KM, Chari R, Deleeuw RJ, Shadeo A, Chi B, Tsao MS, Jones S, Marra M, Ling V, Ng R, Macaulay C, Lam S, Lam WL. Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. American Journal of Respiratory Cell and Molecular Biology. 35: 651-61. PMID 16809635 DOI: 10.1165/Rcmb.2006-0056Oc  0.391
2006 Costa DB, Dayaram T, D'Alo F, Wouters BJ, Tenen DG, Meyerson M, Tsao MS, Halmos B. C/EBP alpha mutations in lung cancer. Lung Cancer (Amsterdam, Netherlands). 53: 253-4. PMID 16765476 DOI: 10.1016/J.Lungcan.2006.04.011  0.368
2006 Sakurada A, Shepherd FA, Tsao MS. Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations. Clinical Lung Cancer. S138-44. PMID 16764754 DOI: 10.3816/Clc.2006.S.005  0.445
2006 Townsley CA, Major P, Siu LL, Dancey J, Chen E, Pond GR, Nicklee T, Ho J, Hedley D, Tsao M, Moore MJ, Oza AM. Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer. British Journal of Cancer. 94: 1136-43. PMID 16570047 DOI: 10.1038/Sj.Bjc.6603055  0.367
2006 Shepherd FA, Tsao MS. Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy [1] Journal of Clinical Oncology. 24: 1219-1220. PMID 16505443 DOI: 10.1200/Jco.2005.04.4420  0.39
2006 Allen T, van Tuyl M, Iyengar P, Jothy S, Post M, Tsao MS, Lobe CG. Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Cancer Research. 66: 1294-301. PMID 16452182 DOI: 10.1158/0008-5472.Can-05-1634  0.442
2006 Tang PA, Tsao M, Moore MJ. A review of erlotinib and its clinical use Expert Opinion On Pharmacotherapy. 7: 177-193. PMID 16433583 DOI: 10.1517/14656566.7.2.177  0.404
2006 Liu J, Costello PC, Pham N, Pintillie M, Jabali M, Sanghera J, Tsao M, Johnston MR. Integrin-Linked Kinase Inhibitor KP-392 Demonstrates Clinical Benefitsin an Orthotopic Human Non-small Cell Lung Cancer Model Journal of Thoracic Oncology. 1: 771-779. DOI: 10.1016/S1556-0864(15)30405-6  0.409
2005 Mackay H, Hedley D, Major P, Townsley C, Mackenzie M, Vincent M, Degendorfer P, Tsao MS, Nicklee T, Birle D, Wright J, Siu L, Moore M, Oza A. A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5526-33. PMID 16061869 DOI: 10.1158/1078-0432.Ccr-05-0081  0.379
2005 Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, Lorimer I, Zhang T, Liu N, Daneshmand M, Marrano P, da Cunha Santos G, Lagarde A, Richardson F, Seymour L, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. The New England Journal of Medicine. 353: 133-44. PMID 16014883 DOI: 10.1056/Nejmoa050736  0.48
2005 Winton T, Livingston R, Johnson D, Rigas J, Johnston M, Butts C, Cormier Y, Goss G, Inculet R, Vallieres E, Fry W, Bethune D, Ayoub J, Ding K, Seymour L, ... ... Tsao MS, et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. The New England Journal of Medicine. 352: 2589-97. PMID 15972865 DOI: 10.1056/Nejmoa043623  0.357
2005 Garnis C, Davies JJ, Buys TP, Tsao MS, MacAulay C, Lam S, Lam WL. Chromosome 5p aberrations are early events in lung cancer: implication of glial cell line-derived neurotrophic factor in disease progression. Oncogene. 24: 4806-12. PMID 15870700 DOI: 10.1038/Sj.Onc.1208643  0.458
2005 Kim RH, Peters M, Jang Y, Shi W, Pintilie M, Fletcher GC, DeLuca C, Liepa J, Zhou L, Snow B, Binari RC, Manoukian AS, Bray MR, Liu FF, Tsao MS, et al. DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell. 7: 263-73. PMID 15766664 DOI: 10.1016/J.Ccr.2005.02.010  0.452
2005 Al-Aynati MM, Radulovich N, Ho J, Tsao MS. Overexpression of G1-S cyclins and cyclin-dependent kinases during multistage human pancreatic duct cell carcinogenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 6598-605. PMID 15475449 DOI: 10.1158/1078-0432.Ccr-04-0524  0.328
2005 Shih W, Chetty R, Tsao M. Expression profiling by microarrays in colorectal cancer (Review). Oncology Reports. 13: 517-524. DOI: 10.3892/Or.13.3.517  0.396
2004 Cully M, Elia A, Ong SH, Stambolic V, Pawson T, Tsao MS, Mak TW. grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 15358-63. PMID 15492213 DOI: 10.1073/Pnas.0406613101  0.317
2004 Blackhall FH, Wigle DA, Jurisica I, Pintilie M, Liu N, Darling G, Johnston MR, Keshavjee S, Waddell T, Winton T, Shepherd FA, Tsao MS. Validating the prognostic value of marker genes derived from a non-small cell lung cancer microarray study. Lung Cancer (Amsterdam, Netherlands). 46: 197-204. PMID 15474668 DOI: 10.1016/J.Lungcan.2004.04.002  0.325
2004 Hagihara A, Miyamoto K, Furuta J, Hiraoka N, Wakazono K, Seki S, Fukushima S, Tsao MS, Sugimura T, Ushijima T. Identification of 27 5' CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers. Oncogene. 23: 8705-10. PMID 15467763 DOI: 10.1038/Sj.Onc.1207783  0.38
2004 Navab R, Gonzalez-Santos JM, Johnston MR, Liu J, Brodt P, Tsao MS, Hu J. Expression of chicken ovalbumin upstream promoter-transcription factor II enhances invasiveness of human lung carcinoma cells. Cancer Research. 64: 5097-105. PMID 15289311 DOI: 10.1158/0008-5472.Can-03-1185  0.461
2004 Liu J, Blackhall F, Seiden-Long I, Jurisica I, Navab R, Liu N, Radulovich N, Wigle D, Sultan M, Hu J, Tsao MS, Johnston MR. Modeling of lung cancer by an orthotopically growing H460SM variant cell line reveals novel candidate genes for systemic metastasis. Oncogene. 23: 6316-24. PMID 15247903 DOI: 10.1038/Sj.Onc.1207795  0.465
2004 Gray PJ, Bearss DJ, Han H, Nagle R, Tsao MS, Dean N, Von Hoff DD. Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer Molecular Cancer Therapeutics. 3: 641-646. PMID 15141022  0.307
2004 Zhu CQ, Blackhall FH, Pintilie M, Iyengar P, Liu N, Ho J, Chomiak T, Lau D, Winton T, Shepherd FA, Tsao MS. Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1984-91. PMID 15041716 DOI: 10.1158/1078-0432.Ccr-03-0470  0.458
2003 Shi W, Zhang X, Pintilie M, Ma N, Miller N, Banerjee D, Tsao MS, Mak T, Fyles A, Liu FF. Dysregulated PTEN-PKB and negative receptor status in human breast cancer. International Journal of Cancer. 104: 195-203. PMID 12569575 DOI: 10.1002/Ijc.10909  0.355
2002 Iyengar P, Tsao MS. Clinical relevance of molecular markers in lung cancer Surgical Oncology. 11: 167-179. PMID 12450553 DOI: 10.1016/S0960-7404(02)00047-6  0.322
2002 Wang KK, Liu N, Radulovich N, Wigle DA, Johnston MR, Shepherd FA, Minden MD, Tsao MS. Novel candidate tumor marker genes for lung adenocarcinoma. Oncogene. 21: 7598-604. PMID 12386823 DOI: 10.1038/sj.onc.1205953  0.363
2002 Wigle DA, Jurisica I, Radulovich N, Pintilie M, Rossant J, Liu N, Lu C, Woodgett J, Seiden I, Johnston M, Keshavjee S, Darling G, Winton T, Breitkreutz BJ, Jorgenson P, ... ... Tsao MS, et al. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Research. 62: 3005-8. PMID 12036904  0.351
2002 To C, Seiden I, Liu N, Wigle D, Tsao MS. High expression of Met/hepatocyte growth factor receptor suppresses tumorigenicity in NCI-H1264 lung carcinoma cells. Experimental Cell Research. 273: 45-53. PMID 11795945 DOI: 10.1006/excr.2001.5433  0.326
2001 Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, Mak TW. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nature Genetics. 29: 396-403. PMID 11726926 DOI: 10.1038/Ng782  0.334
2001 Tsao M, Yang Y, Marcus A, Liu N, Mou L. Hepatocyte growth factor is predominantly expressed by the carcinoma cells in non–small-cell lung cancer Human Pathology. 32: 57-65. PMID 11172296 DOI: 10.1053/Hupa.2001.21133  0.494
2000 Ouyang H, Mou L, Luk C, Liu N, Karaskova J, Squire J, Tsao M. Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype American Journal of Pathology. 157: 1623-1631. PMID 11073822 DOI: 10.1016/S0002-9440(10)64800-6  0.348
2000 Hsieh ETK, Shepherd FA, Tsao M. Co-expression of epidermal growth factor receptor and transforming growth factor-α is independent of ras mutations in lung adenocarcinoma Lung Cancer. 29: 151-157. PMID 10963846 DOI: 10.1016/S0169-5002(00)00116-1  0.381
2000 Yi S, Tsao MS. Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line Neoplasia. 2: 226-234. PMID 10935508 DOI: 10.1038/Sj.Neo.7900080  0.448
2000 Tammemagi MC, Mclaughlin JR, Mullen JBM, Bull SB, Johnston MR, Tsao MS, Casson AG. A study of smoking, p53 tumor suppressor gene alterations and non-small cell lung cancer Annals of Epidemiology. 10: 176-185. PMID 10813511 DOI: 10.1016/S1047-2797(99)00048-4  0.362
2000 Thomas P, Khokha R, Shepherd FA, Feld R, Tsao MS. Differential expression of matrix metalloproteinases and their inhibitors in non-small cell lung cancer. The Journal of Pathology. 190: 150-6. PMID 10657012 DOI: 10.1002/(Sici)1096-9896(200002)190:2<150::Aid-Path510>3.3.Co;2-N  0.322
2000 Michael M, Babic B, Khokha R, Tsao M, Ho J, Pintilie M, Leco K, Chamberlain D, Shepherd FA. Expression and prognostic significance of metalloproteinases and their tissue inhibitors in patients with small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17: 1802-8. PMID 10561218 DOI: 10.1200/Jco.1999.17.6.1802  0.422
1999 Chlenski A, Ketels KV, Engeriser JL, Talamonti MS, Tsao M, Koutnikova H, Oyasu R, Scarpelli DG. zo‐2 gene alternative promoters in normal and neoplastic human pancreatic duct cells International Journal of Cancer. 83: 349-358. PMID 10495427 DOI: 10.1002/(Sici)1097-0215(19991029)83:3<349::Aid-Ijc10>3.0.Co;2-C  0.371
1999 Yang Y, Mou L, Liu N, Tsao M. Autotaxin Expression in Non–Small-Cell Lung Cancer American Journal of Respiratory Cell and Molecular Biology. 21: 216-222. PMID 10423404 DOI: 10.1165/Ajrcmb.21.2.3667  0.433
1999 Chlenski A, Ketels KV, Tsao MS, Talamonti MS, Anderson MR, Oyasu R, Scarpelli DG. Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma. International Journal of Cancer. Journal International Du Cancer. 82: 137-44. PMID 10360833 DOI: 10.1002/(Sici)1097-0215(19990702)82:1<137::Aid-Ijc23>3.0.Co;2-F  0.316
1998 Tsao M, Liu N, Chen J, Pappas J, Ho J, To C, Viallet J, Park M, Zhu H. Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers Lung Cancer. 20: 1-16. PMID 9699182 DOI: 10.1016/S0169-5002(98)00007-5  0.499
1998 Liu N, Furukawa T, Kobari M, Tsao M. Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma. American Journal of Pathology. 153: 263-269. PMID 9665487 DOI: 10.1016/S0002-9440(10)65567-8  0.379
1998 To C, Tsao MS. Effect of RAS oncogene activation on Met/hepatocyte growth factor receptor over-expression in non-small cell lung cancer cells Faseb Journal. 12.  0.316
1997 Casson AG, Wilson SM, Mccart JA, O'Malley FP, Ozcelik H, Tsao MS, Chambers AF. ras mutation and expression of the ras-regulated genes osteopontin and cathepsin L in human esophageal cancer International Journal of Cancer. 72: 739-745. PMID 9311587 DOI: 10.1002/(Sici)1097-0215(19970904)72:5<739::Aid-Ijc6>3.0.Co;2-T  0.404
1996 Marcus VA, Viloria J, Owen D, Tsao MS. Malignant rhabdoid tumor of the colon: Report of a case with molecular analysis Diseases of the Colon and Rectum. 39: 1322-1326. PMID 8918447 DOI: 10.1007/Bf02055131  0.337
1996 Viallet J, Tsao MS, Gallant G. Etoposide and doxorubicin antagonize the in vitro activity of paclitaxel in human non-small cell lung cancer cell lines Lung Cancer. 15: 93-101. PMID 8865127 DOI: 10.1016/0169-5002(96)00574-0  0.306
1996 Tsao MS, Zhu H, Viallet J. Autocrine growth loop of the epidermal growth factor receptor in normal and immortalized human bronchial epithelial cells Experimental Cell Research. 223: 268-273. PMID 8601403 DOI: 10.1006/Excr.1996.0081  0.373
1993 Liu C, Tsao MS. Proto-oncogene and growth factor/receptor expression in the establishment of primary human non-small cell lung carcinoma cell lines American Journal of Pathology. 142: 413-423. PMID 8382008  0.305
1993 Tsao MS. Enhanced expression of alpha-fetoprotein gene in cultured rat liver epithelial cells treated with N-methyl-N’-nitro-N-nitrosoguanidine Pathobiology. 61: 25-30. PMID 7692873 DOI: 10.1159/000163756  0.34
1992 Chang K, Pai LH, Pass H, Pogrebniak HW, Tsao MS, Pastan I, Willingham MC. Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma. The American Journal of Surgical Pathology. 16: 259-68. PMID 1599018 DOI: 10.1097/00000478-199203000-00006  0.356
1992 Wang N, Liu C, Emond J, Tsao M. Annulate Lamellae in a Large Cell Lung Carcinoma Cell Line with High Expression of Tyrosine Kinase Receptor and Proto-Oncogenes Ultrastructural Pathology. 16: 439-449. PMID 1354400 DOI: 10.3109/01913129209057829  0.405
1991 Phillips NC, Tsao MS. Liposomal muramyl dipeptide therapy of experimental M5076 liver metastases in mice Cancer Immunology Immunotherapy. 33: 85-90. PMID 2036662 DOI: 10.1007/Bf01742534  0.32
1991 Batist G, Woo A, Tsao MS. Effect of proliferative state on glutathione s-transferase isoenzyme in cultured rat liver epithelial cells Carcinogenesis. 12: 2031-2034. PMID 1934287 DOI: 10.1093/Carcin/12.11.2031  0.346
1991 Tsao MS, Fraser RS. Primary pulmonary adenocarcinoma with enteric differentiation. Cancer. 68: 1754-7. PMID 1913519 DOI: 10.1002/1097-0142(19911015)68:8<1754::Aid-Cncr2820680818>3.0.Co;2-E  0.356
1989 Tsao MS, Duong M, Batist G. Glutathione and glutathione S-transferases in clones of cultured rat liver epithelial cells that express varying activity of γ-glutamyl transpeptidase Molecular Carcinogenesis. 2: 144-149. PMID 2477028 DOI: 10.1002/Mc.2940020307  0.307
1987 Tsao MS, Duguid WP. Establishment of propagable epithelial cell lines from normal adult rat pancreas Experimental Cell Research. 168: 365-375. PMID 3803447 DOI: 10.1016/0014-4827(87)90009-7  0.316
1987 Byrne JC, Tsao MS, Fraser RS, Howley PM. Human papillomavirus-11 DNA in a patient with chronic laryngotracheobronchial papillomatosis and metastatic squamous-cell carcinoma of the lung. The New England Journal of Medicine. 317: 873-8. PMID 2442608 DOI: 10.1056/Nejm198710013171406  0.319
1984 Tsao MS, Smith JD, Nelson KG, Grisham JW. A diploid epithelial cell line from normal adult rat liver with phenotypic properties of 'oval' cells Experimental Cell Research. 154: 38-52. PMID 6468534 DOI: 10.1016/0014-4827(84)90666-9  0.3
1983 Tsao M, Bilbao J, Richardson P, Finlayson M. Cauda equina paraganglioma. Canadian Journal of Neurological Sciences. 10: 266-269. PMID 6228290 DOI: 10.1017/S0317167100045133  0.329
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