| Year |
Citation |
Score |
| 2023 |
Miyamoto DK, Curnutt NM, Park SM, Stavropoulos A, Kharas MG, Woo CM. Design and Development of IKZF2 and CK1α Dual Degraders. Journal of Medicinal Chemistry. PMID 38085607 DOI: 10.1021/acs.jmedchem.3c01736 |
0.309 |
|
| 2023 |
Luo H, Cortés-López M, Tam CL, Xiao M, Wakiro I, Chu KL, Pierson A, Chan M, Chang K, Yang X, Fecko D, Han G, Ahn EE, Morris QD, Landau DA, ... Kharas MG, et al. SON is an essential mA target for hematopoietic stem cell fate. Cell Stem Cell. 30: 1658-1673.e10. PMID 38065069 DOI: 10.1016/j.stem.2023.11.006 |
0.434 |
|
| 2023 |
Moreira ARS, Lim J, Urbaniak A, Banik J, Bronson K, Lagasse A, Hardy L, Haney A, Allensworth M, Miles TK, Gies A, Byrum SD, Wilczynska A, Boehm U, Kharas M, et al. Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle. Endocrinology. 164. PMID 37477898 DOI: 10.1210/endocr/bqad113 |
0.346 |
|
| 2023 |
Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu KL, Joshi S, Barin E, Schurer A, Chan M, Chang K, Han GYQ, Pierson AJ, Xiao M, Yang X, Kuehm LM, ... ... Kharas MG, et al. RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature Communications. 14: 2290. PMID 37085479 DOI: 10.1038/s41467-023-38001-x |
0.812 |
|
| 2023 |
Kotini AG, Carcamo S, Cruz-Rodriguez N, Olszewska M, Wang T, Demircioglu D, Chang CJ, Bernard E, Chao MP, Majeti R, Luo H, Kharas MG, Hasson D, Papapetrou EP. Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia. Blood Cancer Discovery. OF1-OF18. PMID 37067914 DOI: 10.1158/2643-3230.BCD-22-0167 |
0.341 |
|
| 2023 |
Park SM, Miyamoto DK, Han GYQ, Chan M, Curnutt NM, Tran NL, Velleca A, Kim JH, Schurer A, Chang K, Xu W, Kharas MG, Woo CM. Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells. Cancer Cell. PMID 36898380 DOI: 10.1016/j.ccell.2023.02.010 |
0.362 |
|
| 2023 |
Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, ... ... Kharas MG, et al. mutation yields supercompetitive B cells primed for malignant transformation. Science (New York, N.Y.). 379: eabj7412. PMID 36656933 DOI: 10.1126/science.abj7412 |
0.799 |
|
| 2022 |
Erazo T, Evans CM, Zakheim D, Chu KL, Refermat AY, Asgari Z, Yang X, Da Silva Ferreira M, Mehta S, Russo MV, Knezevic A, Zhang XP, Chen Z, Fennell M, Garippa R, ... ... Kharas MG, et al. TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma. Nature Communications. 13: 5676. PMID 36167829 DOI: 10.1038/s41467-022-33137-8 |
0.64 |
|
| 2022 |
Klatt MG, Dao T, Yang Z, Liu J, Mun SS, Dacek MM, Luo H, Gardner TJ, Bourne CM, Peraro L, Aretz ZEH, Korontsvit T, Lau M, Kharas MG, Liu C, et al. A TCR Mimic CAR T Cell Specific for NDC80 Is Broadly Reactive With Solid Tumors and Hematological Malignancies. Blood. PMID 35427421 DOI: 10.1182/blood.2021012882 |
0.307 |
|
| 2021 |
Prieto C, Nguyen DTT, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E, Velleca A, Rohwetter T, Chow A, Taggart J, Savino AM, Hoskova K, Dhodapkar M, ... ... Kharas MG, et al. Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia. Nature Cancer. 2: 741-757. PMID 34458856 DOI: 10.1038/s43018-021-00220-w |
0.746 |
|
| 2021 |
Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT, Mo S, Barin E, Velleca A, Rohwetter TM, Patel DJ, Jaffrey SR, Kharas MG. N-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation. Cancer Cell. PMID 34048709 DOI: 10.1016/j.ccell.2021.04.017 |
0.8 |
|
| 2021 |
Granatiero V, Sayles NM, Savino AM, Konrad C, Kharas MG, Kawamata H, Manfredi G. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1 astrocytes. Autophagy. 1-14. PMID 33749521 DOI: 10.1080/15548627.2021.1899682 |
0.751 |
|
| 2021 |
Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 162. PMID 33570120 DOI: 10.1210/endocr/bqaa245 |
0.354 |
|
| 2021 |
Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 162. PMID 33508117 DOI: 10.1210/endocr/bqaa245 |
0.354 |
|
| 2021 |
Palacios F, Yan XJ, Ferrer G, Chen SS, Vergani S, Yang X, Gardner J, Barrientos JC, Rock P, Burack R, Kolitz JE, Allen SL, Kharas MG, Abdel-Wahab O, Rai KR, et al. Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target. Leukemia. PMID 33504942 DOI: 10.1038/s41375-020-01115-y |
0.49 |
|
| 2020 |
Savino AM, Fernandes SI, Olivares O, Zemlyansky A, Cousins A, Markert EK, Barel S, Geron I, Frishman L, Birger Y, Eckert C, Tumanov S, MacKay G, Kamphorst JJ, Herzyk P, ... ... Kharas MG, et al. Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment is dependent on Stearoyl CoA desaturase. Nature Cancer. 1: 998-1009. PMID 33479702 DOI: 10.1038/s43018-020-00115-2 |
0.748 |
|
| 2020 |
Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the anterior pituitary cell lineage regulator POU1F1 by the stem cell determinant Musashi. Endocrinology. PMID 33373440 DOI: 10.1210/endocr/bqaa245 |
0.347 |
|
| 2020 |
Jeong S, Savino AM, Chirayil R, Barin E, Cheng Y, Park SM, Schurer A, Mullarky E, Cantley LC, Kharas MG, Keshari KR. High Fructose Drives the Serine Synthesis Pathway in Acute Myeloid Leukemic Cells. Cell Metabolism. PMID 33357456 DOI: 10.1016/j.cmet.2020.12.005 |
0.8 |
|
| 2020 |
Lee SG, Muralidhar Kalidindi T, Lou H, Gangangari K, Punzalan B, Bitton A, Lee C, Park S, Bodei L, Kharas M, Singh VK, Pillarsetty N, Larson SM. Gamma-Tocotrienol loaded liposomes as radioprotection from hematopoietic side effects caused by radiotherapeutic drugs. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32826318 DOI: 10.2967/Jnumed.120.244681 |
0.322 |
|
| 2020 |
Cheng Y, Luo H, Kharas MG. Rubbing Out Leukemia Stem Cells by Erasing the Eraser. Cell Stem Cell. 27: 3-5. PMID 32619516 DOI: 10.1016/j.stem.2020.06.009 |
0.79 |
|
| 2020 |
Wesely J, Kotini AG, Izzo F, Luo H, Yuan H, Sun J, Georgomanoli M, Zviran A, Deslauriers AG, Dusaj N, Nimer SD, Leslie C, Landau DA, Kharas MG, Papapetrou EP. Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells. Cell Reports. 31: 107688. PMID 32492433 DOI: 10.1016/J.Celrep.2020.107688 |
0.443 |
|
| 2020 |
Nguyen DTT, Lu Y, Chu KL, Yang X, Park SM, Choo ZN, Chin CR, Prieto C, Schurer A, Barin E, Savino AM, Gourkanti S, Patel P, Vu LP, Leslie CS, ... Kharas MG, et al. HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells. Nature Communications. 11: 2026. PMID 32332729 DOI: 10.1038/S41467-020-15814-8 |
0.781 |
|
| 2020 |
Moreira ARS, Lagasse AN, Haney AC, Avaritt N, Byrum S, Boehm U, Kharas MG, Lengner CJ, MacNicol MC, Childs GV, MacNicol AM, Odle AK. SAT-292 Musashi: A Novel Regulator of the Gonadotrope Transcriptome Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1487 |
0.387 |
|
| 2020 |
Nguyen DT, Prieto C, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E, Chow A, Taggart J, Hoskova K, Dhodapkar M, Schurer A, Barlowe TS, Vu L, ... ... Kharas MG, et al. Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia Blood. 136: 15-15. DOI: 10.1182/BLOOD-2020-142229 |
0.469 |
|
| 2019 |
Prieto C, Kharas MG. RNA Regulators in Leukemia and Lymphoma. Cold Spring Harbor Perspectives in Medicine. PMID 31615866 DOI: 10.1101/cshperspect.a034967 |
0.81 |
|
| 2019 |
Cheng Y, Luo H, Izzo F, Pickering BF, Nguyen D, Myers R, Schurer A, Gourkanti S, Brüning JC, Vu LP, Jaffrey SR, Landau DA, Kharas MG. mA RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Reports. 28: 1703-1716.e6. PMID 31412241 DOI: 10.1016/J.Celrep.2019.07.032 |
0.801 |
|
| 2019 |
Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A, Schurer A, Park SM, Rotsides CZ, Taggart J, Rizzi A, Naden LN, Chou T, Gourkanti S, Cappel D, ... ... Kharas MG, et al. Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nature Communications. 10: 2691. PMID 31217428 DOI: 10.1038/S41467-019-10523-3 |
0.818 |
|
| 2019 |
Vu LP, Cheng Y, Kharas MG. The Biology of mA RNA Methylation in Normal and Malignant Hematopoiesis. Cancer Discovery. 9: 25-33. PMID 30578356 DOI: 10.1158/2159-8290.CD-18-0959 |
0.821 |
|
| 2019 |
Allensworth-James M, Odle A, Silva Moreira AR, Miles T, Haney A, Kharas M, Lengner C, MacNicol M, MacNicol A, Childs G. OR24-3 Persistence of Progenitor Cell Markers Following the Selective Ablation of Musashi in Somatotropes Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or24-3 |
0.4 |
|
| 2018 |
Park SM, Cho H, Thornton AM, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Taggart J, Chow A, Schurer A, Gruet A, Witkin MD, Kim JH, Shevach EM, Krivtsov A, ... ... Kharas MG, et al. IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation. Cell Stem Cell. PMID 30472158 DOI: 10.1016/J.Stem.2018.10.016 |
0.415 |
|
| 2018 |
Sengupta U, Montalbano M, McAllen S, Minuesa G, Kharas M, Kayed R. Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease. Acta Neuropathologica Communications. 6: 113. PMID 30367664 DOI: 10.1186/S40478-018-0615-0 |
0.312 |
|
| 2018 |
Vu LP, Kharas MG. Targeting the Residual Leukemia Cells after Chemotherapy. Cancer Cell. 34: 353-355. PMID 30205040 DOI: 10.1016/j.ccell.2018.08.012 |
0.731 |
|
| 2018 |
Ramaswamy K, Forbes L, Minuesa G, Gindin T, Brown F, Kharas MG, Krivtsov AV, Armstrong SA, Still E, de Stanchina E, Knoechel B, Koche R, Kentsis A. Peptidomimetic blockade of MYB in acute myeloid leukemia. Nature Communications. 9: 110. PMID 29317678 DOI: 10.1038/s41467-017-02618-6 |
0.379 |
|
| 2018 |
Nguyen D, Lu Y, Choo Z, Chin C, Prieto C, Gourkanti S, Leslie C, Kharas MG. The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells Blood. 132: 884-884. DOI: 10.1182/Blood-2018-99-118949 |
0.841 |
|
| 2018 |
Cheng Y, Luo H, Izzo F, Pickering BF, Vu LP, Schurer A, Gourkanti S, Jaffrey SR, Landau DA, Kharas MG. m6A Maintains Hematopoietic Stem and Progenitor Cell Identity Blood. 132: 327-327. DOI: 10.1182/Blood-2018-99-117191 |
0.846 |
|
| 2018 |
Park S, Cho H, Thornton A, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Chow A, Taggart J, Schurer A, Gruet A, Witkin M, Kim JH, Shevach E, Krivstov A, ... ... Kharas MG, et al. IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells Blood. 132: 3881-3881. DOI: 10.1182/Blood-2018-99-115034 |
0.454 |
|
| 2018 |
Prieto C, Nguyen D, Vu LP, Perez A, Gourkanti S, Schurer A, Chou T, Chow A, Taggart J, Barlowe TS, Leslie C, Kharas MG. RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α Blood. 132: 883-883. DOI: 10.1182/Blood-2018-99-112543 |
0.805 |
|
| 2018 |
Wesely J, Kotini AG, Georgomanoli M, Luo H, Yuan H, Izzo F, Landau DA, Leslie C, Kharas MG, Papapetrou EP. A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells Blood. 132: 772-772. DOI: 10.1182/Blood-2018-99-111506 |
0.477 |
|
| 2017 |
Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, Schulman J, Famulare C, Patel M, Klimek VM, Garrett-Bakelman FE, ... ... Kharas MG, et al. The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nature Medicine. PMID 28920958 DOI: 10.1038/Nm.4416 |
0.822 |
|
| 2017 |
Kharas MG, Lengner CJ. Stem Cells, Cancer, and MUSASHI in Blood and Guts. Trends in Cancer. 3: 347-356. PMID 28718412 DOI: 10.1016/j.trecan.2017.03.007 |
0.37 |
|
| 2017 |
Kharas MG, Janes MR, Scarfone VM, Lilly MB, Knight ZA, Shokat KM, Fruman DA. Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells. The Journal of Clinical Investigation. 127: 2438. PMID 28569734 DOI: 10.1172/JCI95182 |
0.771 |
|
| 2017 |
Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, ... ... Kharas MG, et al. Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells. Nature Genetics. PMID 28436985 DOI: 10.1038/Ng.3854 |
0.833 |
|
| 2017 |
Vu LP, Pickering BF, Cheng Y, Sara Z, Nguyen D, Minuesa G, Chou T, Chow A, MacKay M, Famulare C, Patel M, Garret-Bakelman F, Melnick A, Carroll M, Mason C, ... ... Kharas MG, et al. m6a Regulates Differentiation State and mRNA Translation in Myeloid Leukemia Blood. 130: 791-791. DOI: 10.1182/BLOOD.V130.SUPPL_1.791.791 |
0.502 |
|
| 2017 |
Vu L, Prieto C, Amin EM, Minuesa G, Chhangawala S, Vidal MC, Krivtsov A, Chou T, Chow A, Barlowe T, Taggart J, Tivnan P, Deering RP, Chu LP, Gonen M, ... ... Kharas MG, et al. Abstract IA13: RNA regulators and the control of self-renewal Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Hemmal17-Ia13 |
0.526 |
|
| 2016 |
Yousefi M, Li N, Nakauka-Ddamba A, Wang S, Davidow K, Schoenberger J, Yu Z, Jensen ST, Kharas MG, Lengner CJ. Msi RNA-binding proteins control reserve intestinal stem cell quiescence. The Journal of Cell Biology. PMID 27799368 DOI: 10.1083/Jcb.201604119 |
0.398 |
|
| 2016 |
Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, ... ... Kharas MG, et al. MSI2 is required for maintaining activated myelodysplastic syndrome stem cells. Nature Communications. 7: 10739. PMID 26898884 DOI: 10.1038/Ncomms10739 |
0.82 |
|
| 2016 |
Vu LP, Prieto C, Amin E, Minuesa G, Chhangawala S, Vidal MJ, Krivtsov AV, Chou T, Barlowe T, Taggart J, Tivnan P, Deering RP, Gonen M, Figueroa ME, Paietta E, ... ... Kharas MG, et al. RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program Blood. 128: 739-739. DOI: 10.1182/Blood.V128.22.739.739 |
0.529 |
|
| 2015 |
Wang S, Li N, Yousefi M, Nakauka-Ddamba A, Li F, Parada K, Rao S, Minuesa G, Katz Y, Gregory BD, Kharas MG, Yu Z, Lengner CJ. Transformation of the intestinal epithelium by the MSI2 RNA-binding protein. Nature Communications. 6: 6517. PMID 25774828 DOI: 10.1038/Ncomms7517 |
0.401 |
|
| 2015 |
Park SM, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe TS, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa ME, Paietta E, Fernandez HF, Tallman MS, Melnick A, ... ... Kharas MG, et al. Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. The Journal of Clinical Investigation. 125: 1286-98. PMID 25664853 DOI: 10.1172/Jci78440 |
0.769 |
|
| 2015 |
Ho T, Taggart J, Amin E, Xu H, Barlowe T, Perez AR, Tivnan P, Okabe R, Lengner C, Verma A, Roboz GJ, Guzman ML, Leslie CS, Nimer SD, Kharas MG. MSI2 Is Required for Maintaining the Activated Myelodysplastic Syndrome Stem Cell Blood. 126: 714-714. DOI: 10.1182/Blood.V126.23.714.714 |
0.399 |
|
| 2015 |
Park SM, Thornton A, Vu LP, Chhangawala S, Minuesa G, Barlowe T, Taggart J, Tivnan P, Kim T, Shevach E, Leslie CS, Kharas MG. IKZF2, a Novel Target of MSI2 RNA-Binding Protein Plays an Oncogenic Role in Myeloid Leukemia Blood. 126: 440-440. DOI: 10.1182/BLOOD.V126.23.440.440 |
0.477 |
|
| 2014 |
Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, et al. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. The Journal of Experimental Medicine. 211: 605-12. PMID 24616378 DOI: 10.1084/Jem.20131033 |
0.378 |
|
| 2014 |
Park SM, Deering RP, Lu Y, Tivnan P, Lianoglou S, Al-Shahrour F, Ebert BL, Hacohen N, Leslie C, Daley GQ, Lengner CJ, Kharas MG. Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. The Journal of Experimental Medicine. 211: 71-87. PMID 24395885 DOI: 10.1084/Jem.20130736 |
0.602 |
|
| 2014 |
Park SM, Gönen M, Vu LP, Minuesa G, Tivnan P, Barlowe T, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa M, Paietta EM, Tallman MS, Melnick AM, Levine RL, ... ... Kharas MG, et al. Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program Blood. 124: 836-836. DOI: 10.1182/Blood.V124.21.836.836 |
0.464 |
|
| 2014 |
Amin EM, Kharas MG. The Riboproteome Orchestrates Self-Renewal and Cell Fate in Leukemia Cancer Stem Cells. 417-434. DOI: 10.1002/9781118356203.ch31 |
0.413 |
|
| 2013 |
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, et al. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 24: 45-58. PMID 23770013 DOI: 10.1016/J.Ccr.2013.05.004 |
0.453 |
|
| 2013 |
Park S, Deering RP, Lu Y, Patrick T, Shenoy V, Lianoglou S, Al-Shahrour F, Leslie C, Ebert BL, Lengner C, Daley GQ, Kharas MG. Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells Blood. 122: 468-468. DOI: 10.1182/Blood.V122.21.468.468 |
0.558 |
|
| 2012 |
Park SM, Deering R, Lu Y, Tivnan P, Shenoy V, Lianoglou S, Al-Shahrour F, Leslie C, Ebert BL, Lengner C, Daley GQ, Kharas MG. Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate. Blood. 120: 2324-2324. DOI: 10.1182/Blood.V120.21.2324.2324 |
0.657 |
|
| 2012 |
Järås M, Miller PG, Chu L, Schneider RK, Puram RV, Al-Shahrour F, Fink E, Hartwell KA, McConkey M, Cowley G, Mullally A, Kharas MG, Ebert BL. Casein Kinase 1 Alpha Maintains Normal and Leukemic Stem Cells by Regulating p53 Activity Blood. 120: 209-209. DOI: 10.1182/blood.v120.21.209.209 |
0.416 |
|
| 2011 |
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell. 147: 81-94. PMID 21962509 DOI: 10.1016/J.Cell.2011.08.033 |
0.425 |
|
| 2011 |
Brigham PMGS, Miller W, Al-Shahrour F, Hartwell KA, Chu LP, Marcus J, Puram RV, Puissant A, Callahan K, Ashton JM, McConkey ME, Poveromo L, Cowley G, Kharas MG, Labelle M, et al. In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling Blood. 118: 758-758. DOI: 10.1182/Blood.V118.21.758.758 |
0.445 |
|
| 2011 |
Kharas MG, Lengner C, Al-Shahrour F, Ebert BL, Daley GQ. Msi2 Maintains Normal Hematopoietic Stem Cell Self-Renewal Blood. 118: 222-222. DOI: 10.1182/Blood.V118.21.222.222 |
0.606 |
|
| 2010 |
Kharas MG, Daley GQ. From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond. Genes & Cancer. 1: 1164-9. PMID 21779439 DOI: 10.1177/1947601911407327 |
0.42 |
|
| 2010 |
Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, Morgan K, Tam W, Paktinat M, Okabe R, Gozo M, Einhorn W, Lane SW, Scholl C, Fröhling S, et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine. 16: 903-8. PMID 20616797 DOI: 10.1038/Nm.2187 |
0.614 |
|
| 2010 |
Mullally A, Lane SW, Ball B, Megerdichian C, Okabe R, Al-Shahrour F, Paktinat M, Haydu JE, Housman E, Lord AM, Wernig G, Kharas MG, Mercher T, Kutok JL, Gilliland DG, et al. Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells Cancer Cell. 17: 584-596. PMID 20541703 DOI: 10.1016/j.ccr.2010.05.015 |
0.349 |
|
| 2010 |
Kharas MG, Okabe R, Ganis JJ, Gozo M, Khandan T, Paktinat M, Gilliland DG, Gritsman K. Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice. Blood. 115: 1406-15. PMID 20008787 DOI: 10.1182/Blood-2009-06-229443 |
0.412 |
|
| 2009 |
Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, et al. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 4: 559-67. PMID 19497284 DOI: 10.1016/J.Stem.2009.03.016 |
0.369 |
|
| 2009 |
Oak JS, Deane JA, Kharas MG, Luo J, Lane TE, Cantley LC, Fruman DA. Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase (Proceedings of the National Academy of Sciences of the United States of America (2009) 103, 45, (16882-16887) 10.1073/pnas. 0607984103) Proceedings of the National Academy of Sciences of the United States of America. 106: 10871. DOI: 10.1073/Pnas.0905401106 |
0.772 |
|
| 2008 |
Morgan K, Kharas M, Dzierzak E, Gilliland DG. Isolation of early hematopoietic stem cells from murine yolk sac and AGM. Journal of Visualized Experiments : Jove. PMID 19066546 DOI: 10.3791/789 |
0.465 |
|
| 2008 |
Kharas MG, Janes MR, Scarfone VM, Lilly MB, Knight ZA, Shokat KM, Fruman DA. Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells. The Journal of Clinical Investigation. 118: 3038-50. PMID 18704194 DOI: 10.1172/Jci33337 |
0.786 |
|
| 2008 |
Yusuf I, Kharas MG, Chen J, Peralta RQ, Maruniak A, Sareen P, Yang VW, Kaestner KH, Fruman DA. KLF4 is a FOXO target gene that suppresses B cell proliferation. International Immunology. 20: 671-81. PMID 18375530 DOI: 10.1093/Intimm/Dxn024 |
0.827 |
|
| 2008 |
Morgan K, Kharas M, Dzierzak E, Gilliland DG. Isolation of early hematopoietic stem cells from murine Yolk Sac and AGM Journal of Visualized Experiments. DOI: 10.3791/789 |
0.359 |
|
| 2008 |
Kharas M, Manis J, Gilliland DG, Raffel GD. Ott1 (Rbm15) Is Required for the Large to Small Pre B-Cell Transition Blood. 112: 706-706. DOI: 10.1182/Blood.V112.11.706.706 |
0.446 |
|
| 2008 |
Zhang IH, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Okabe R, Armstrong SA, Ghilardi N, Gould S, deSauvage FJ, McMahon AP, Gilliland DG. Hedgehog Signaling Is Dispensable for Adult Murine Hematopoiesis and Leukemogenesis. Blood. 112: 1391-1391. DOI: 10.1182/blood.v112.11.1391.1391 |
0.317 |
|
| 2007 |
Donahue AC, Kharas MG, Fruman DA. Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. Methods in Enzymology. 434: 131-54. PMID 17954246 DOI: 10.1016/S0076-6879(07)34008-1 |
0.789 |
|
| 2007 |
Deane JA, Kharas MG, Oak JS, Stiles LN, Luo J, Moore TI, Ji H, Rommel C, Cantley LC, Lane TE, Fruman DA. T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Blood. 109: 2894-902. PMID 17164340 DOI: 10.1182/Blood-2006-07-038620 |
0.797 |
|
| 2007 |
Kharas MG, Yusuf I, Scarfone VM, Yang VW, Segre JA, Huettner CS, Fruman DA. KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood. 109: 747-55. PMID 16954505 DOI: 10.1182/Blood-2006-03-011106 |
0.822 |
|
| 2007 |
Cornejo MG, Kharas MG, Lee B, Moore SA, Gilliland G, Mercher T. Constitutive JAK3 Activation as a Mouse Model for Human Peripheral T-Cell Lymphoma. Blood. 110: 1612-1612. DOI: 10.1182/blood.v110.11.1612.1612 |
0.38 |
|
| 2006 |
Oak JS, Deane JA, Kharas MG, Luo J, Lane TE, Cantley LC, Fruman DA. Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase. Proceedings of the National Academy of Sciences of the United States of America. 103: 16882-7. PMID 17071741 DOI: 10.1073/Pnas.0607984103 |
0.79 |
|
| 2005 |
Cruz R, Hedden L, Boyer D, Kharas MG, Fruman DA, Lee-Fruman KK. S6 kinase 2 potentiates interleukin-3-driven cell proliferation. Journal of Leukocyte Biology. 78: 1378-85. PMID 16204634 DOI: 10.1189/Jlb.0405225 |
0.576 |
|
| 2005 |
Kharas MG, Fruman DA. ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors. Cancer Research. 65: 2047-53. PMID 15781610 DOI: 10.1158/0008-5472.Can-04-3888 |
0.573 |
|
| 2004 |
Yusuf I, Zhu X, Kharas MG, Chen J, Fruman DA. Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors. Blood. 104: 784-7. PMID 15069012 DOI: 10.1182/Blood-2003-09-3071 |
0.823 |
|
| 2004 |
Kharas MG, Deane JA, Wong S, O'Bosky KR, Rosenberg N, Witte ON, Fruman DA. Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells. Blood. 103: 4268-75. PMID 14976048 DOI: 10.1182/Blood-2003-07-2193 |
0.809 |
|
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