| Year |
Citation |
Score |
| 2023 |
Zhou L, Yang L, Feng Y, Chen S. Pooled screening with next-generation gene editing tools. Current Opinion in Biomedical Engineering. 28. PMID 38222973 DOI: 10.1016/j.cobme.2023.100479 |
0.454 |
|
| 2023 |
Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M. The H2Bub1-deposition complex is required for human and mouse cardiogenesis. Development (Cambridge, England). 150. PMID 38038666 DOI: 10.1242/dev.201899 |
0.343 |
|
| 2023 |
Zhou X, Renauer PA, Zhou L, Fang SY, Chen S. Applications of CRISPR technology in cellular immunotherapy. Immunological Reviews. PMID 37449673 DOI: 10.1111/imr.13241 |
0.313 |
|
| 2023 |
Zhang L, Park JJ, Dong MB, Arsala D, Xia S, Chen J, Sosa D, Atlas JE, Long M, Chen S. Human gene age dating reveals an early and rapid evolutionary construction of the adaptive immune system. Genome Biology and Evolution. PMID 37170918 DOI: 10.1093/gbe/evad081 |
0.798 |
|
| 2023 |
Dong MB, Tang K, Zhou X, Shen J, Chen K, Kim HR, Zhou J, Cao H, Vandenbulcke E, Zhang Y, Chow RD, Du A, Suzuki K, Fang SY, Majety M, ... ... Chen S, et al. Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering. Biorxiv : the Preprint Server For Biology. PMID 36993642 DOI: 10.1101/2023.03.14.532657 |
0.329 |
|
| 2022 |
Park JJ, Codina A, Ye L, Lam S, Guo J, Clark P, Zhou X, Peng L, Chen S. Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity. Journal of Hematology & Oncology. 15: 172. PMID 36456981 DOI: 10.1186/s13045-022-01389-y |
0.323 |
|
| 2021 |
Xia S, VanKuren NW, Chen C, Zhang L, Kemkemer C, Shao Y, Jia H, Lee U, Advani AS, Gschwend A, Vibranovski MD, Chen S, Zhang YE, Long M. Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development. Plos Genetics. 17: e1009654. PMID 34242211 DOI: 10.1371/journal.pgen.1009654 |
0.829 |
|
| 2020 |
Wang G, Chow RD, Zhu L, Bai Z, Ye L, Zhang F, Renauer PA, Dong MB, Dai X, Zhang X, Du Y, Cheng Y, Niu L, Chu Z, Kim K, ... ... Chen S, et al. CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade. Cancer Discovery. PMID 32887696 DOI: 10.1158/2159-8290.Cd-19-1448 |
0.333 |
|
| 2019 |
Wang G, Chow RD, Bai Z, Zhu L, Errami Y, Dai X, Dong MB, Ye L, Zhang X, Renauer PA, Park JJ, Shen L, Ye H, Fuchs CS, Chen S. Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity. Nature Immunology. PMID 31611701 DOI: 10.1038/S41590-019-0500-4 |
0.448 |
|
| 2019 |
Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S. In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma. Nature Biotechnology. PMID 31548728 DOI: 10.1038/S41587-019-0246-4 |
0.305 |
|
| 2019 |
Chow RD, Wang G, Ye L, Codina A, Kim HR, Shen L, Dong MB, Errami Y, Chen S. In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens. Nature Methods. PMID 30962622 DOI: 10.1038/S41592-019-0371-5 |
0.396 |
|
| 2019 |
Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, ... ... Chen S, et al. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Systems. PMID 30797773 DOI: 10.1016/J.Cels.2019.01.004 |
0.328 |
|
| 2019 |
Wang G, Chow R, Bai Z, Ye L, Chen S. Abstract B095: Mapping the genetic features of immune checkpoint responsiveness using AAV-CRISPR mediated in vivo screen Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B095 |
0.318 |
|
| 2018 |
Ye L, Wang C, Hong L, Sun N, Chen D, Chen S, Han F. Programmable DNA repair with CRISPRa/i enhanced homology-directed repair efficiency with a single Cas9. Cell Discovery. 4: 46. PMID 30062046 DOI: 10.1038/S41421-018-0049-7 |
0.414 |
|
| 2018 |
Chow RD, Kim HR, Chen S. Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion. Nature Communications. 9: 1903. PMID 29765043 DOI: 10.1038/S41467-018-04158-Z |
0.332 |
|
| 2018 |
Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science Advances. 4: eaao5508. PMID 29503867 DOI: 10.1126/Sciadv.Aao5508 |
0.346 |
|
| 2017 |
Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, ... ... Chen S, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature Neuroscience. PMID 28805815 DOI: 10.1038/Nn.4620 |
0.429 |
|
| 2016 |
Yi S, Chen S, Zhang L, Sahni N. Signal Transduction and Regulation: Insights into Evolution. Biomed Research International. 2016: 8604245. PMID 27525280 DOI: 10.1155/2016/8604245 |
0.381 |
|
| 2015 |
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/J.Cell.2015.02.038 |
0.422 |
|
| 2014 |
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55. PMID 25263330 DOI: 10.1016/J.Cell.2014.09.014 |
0.367 |
|
| 2014 |
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 514: 380-4. PMID 25119044 DOI: 10.1038/Nature13589 |
0.466 |
|
| 2014 |
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889 |
0.31 |
|
| 2014 |
Yin H, Xue W, Chen S, Bogorad RL, Benedetti E, Grompe M, Koteliansky V, Sharp PA, Jacks T, Anderson DG. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nature Biotechnology. 32: 551-3. PMID 24681508 DOI: 10.1038/Nbt.2884 |
0.341 |
|
| 2013 |
Long M, VanKuren NW, Chen S, Vibranovski MD. New gene evolution: little did we know. Annual Review of Genetics. 47: 307-33. PMID 24050177 DOI: 10.1146/Annurev-Genet-111212-133301 |
0.812 |
|
| 2013 |
Chen S, Krinsky BH, Long M. New genes as drivers of phenotypic evolution. Nature Reviews. Genetics. 14: 645-60. PMID 23949544 DOI: 10.1038/Nrg3521 |
0.821 |
|
| 2013 |
Chen S, Krinsky BH, Long M. Erratum: New genes as drivers of phenotypic evolution Nature Reviews Genetics. 14: 744-744. DOI: 10.1038/Nrg3584 |
0.811 |
|
| 2012 |
Ni X, Zhang YE, Nègre N, Chen S, Long M, White KP. Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome. Plos Biology. 10: e1001420. PMID 23139640 DOI: 10.1371/Journal.Pbio.1001420 |
0.615 |
|
| 2012 |
Chen S, Spletter M, Ni X, White KP, Luo L, Long M. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Cell Reports. 1: 118-32. PMID 22832161 DOI: 10.1016/J.Celrep.2011.12.010 |
0.651 |
|
| 2012 |
Chen S, Ni X, Krinsky BH, Zhang YE, Vibranovski MD, White KP, Long M. Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene. The Embo Journal. 31: 2798-809. PMID 22543869 DOI: 10.1038/Emboj.2012.108 |
0.792 |
|
| 2011 |
Chen S, Yang H, Krinsky BH, Zhang A, Long M. Roles of young serine-endopeptidase genes in survival and reproduction revealed rapid evolution of phenotypic effects at adult stages. Fly. 5: 345-51. PMID 21946255 DOI: 10.4161/Fly.5.4.17808 |
0.795 |
|
| 2011 |
Chen Y, Dai H, Chen S, Zhang L, Long M. Highly tissue specific expression of Sphinx supports its male courtship related role in Drosophila melanogaster. Plos One. 6: e18853. PMID 21541324 DOI: 10.1371/Journal.Pone.0018853 |
0.73 |
|
| 2010 |
Chen S, Zhang YE, Long M. New genes in Drosophila quickly become essential. Science (New York, N.Y.). 330: 1682-5. PMID 21164016 DOI: 10.1126/Science.1196380 |
0.764 |
|
| 2008 |
Dai H, Chen Y, Chen S, Mao Q, Kennedy D, Landback P, Eyre-Walker A, Du W, Long M. The evolution of courtship behaviors through the origination of a new gene in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 105: 7478-83. PMID 18508971 DOI: 10.1073/Pnas.0800693105 |
0.778 |
|
| 2003 |
Chen X, Feng Q, Wu Z, Liu Y, Huang K, Shi R, Chen S, Lu W, Ding M, Collins RA, Fung YW, Lau LT, Yu AC, Chen J. RNA-dependent RNA polymerase gene sequence from foot-and-mouth disease virus in Hong Kong. Biochemical and Biophysical Research Communications. 308: 899-905. PMID 12927804 DOI: 10.1016/S0006-291X(03)01511-0 |
0.415 |
|
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